KEGG   PATHWAY: maua04024
Entry
maua04024                   Pathway                                
Name
cAMP signaling pathway - Mesocricetus auratus (golden hamster)
Description
cAMP is one of the most common and universal second messengers, and its formation is promoted by adenylyl cyclase (AC) activation after ligation of G protein-coupled receptors (GPCRs) by ligands including hormones, neurotransmitters, and other signaling molecules. cAMP regulates pivotal physiologic processes including metabolism, secretion, calcium homeostasis, muscle contraction, cell fate, and gene transcription. cAMP acts directly on three main targets: protein kinase A (PKA), the exchange protein activated by cAMP (Epac), and cyclic nucleotide-gated ion channels (CNGCs). PKA modulates, via phosphorylation, a number of cellular substrates, including transcription factors, ion channels, transporters, exchangers, intracellular Ca2+ -handling proteins, and the contractile machinery. Epac proteins function as guanine nucleotide exchange factors (GEFs) for both Rap1 and Rap2. Various effector proteins, including adaptor proteins implicated in modulation of the actin cytoskeleton, regulators of G proteins of the Rho family, and phospholipases, relay signaling downstream from Rap.
Class
Environmental Information Processing; Signal transduction
Pathway map
maua04024  cAMP signaling pathway
maua04024

Other DBs
GO: 0019933
Organism
Mesocricetus auratus (golden hamster) [GN:maua]
Gene
101827292  VIP peptides isoform X1 [KO:K05264]
101827824  Crh; corticoliberin [KO:K05256]
101835965  Cga; glycoprotein hormones alpha chain precursor [KO:K08522]
101844504  Lhb; luteinizing hormone beta polypeptide precursor [KO:K08521]
101844503  Gpha2; glycoprotein hormone alpha-2 isoform X1 [KO:K25483]
106021363  Gphb5; glycoprotein hormone beta-5 [KO:K25484]
101830447  Tshb; thyrotropin subunit beta [KO:K05251]
101822777  Pomc; pro-opiomelanocortin [KO:K05228]
106021062  Gcg; pro-glucagon isoform X1 [KO:K05259]
101827768  gastric inhibitory polypeptide [KO:K05258]
101838709  Fshb; follitropin subunit beta precursor [KO:K05250]
101838783  Nppa; natriuretic peptides A [KO:K12334]
101837445  Adcyap1; pituitary adenylate cyclase-activating polypeptide isoform X1 [KO:K05262]
101830640  Adrb1; beta-1 adrenergic receptor [KO:K04141]
101836719  Adrb2; beta-2 adrenergic receptor [KO:K04142]
101843956  Drd1; D(1A) dopamine receptor [KO:K04144]
101833579  Drd5; D(1B) dopamine receptor [KO:K05840]
101824159  Adora2a; adenosine receptor A2a [KO:K04266]
101836030  Htr4; 5-hydroxytryptamine receptor 4 isoform X1 [KO:K04160]
101833956  Htr6; 5-hydroxytryptamine receptor 6 [KO:K04162]
101826580  Ptger2; prostaglandin E2 receptor EP2 subtype isoform X1 [KO:K04259]
101835337  Adcyap1r1; pituitary adenylate cyclase-activating polypeptide type I receptor isoform X1 [KO:K04587]
101838533  Vipr2; vasoactive intestinal polypeptide receptor 2 [KO:K04590]
101829697  Crhr1; corticotropin-releasing factor receptor 1 precursor [KO:K04578]
101840384  Crhr2; corticotropin-releasing factor receptor 2 isoform X5 [KO:K04579]
101835084  Lhcgr; lutropin-choriogonadotropic hormone receptor isoform X1 [KO:K04248]
101843573  Tshr; thyrotropin receptor [KO:K04249]
101825745  Mc2r; adrenocorticotropic hormone receptor [KO:K04200]
101827751  Glp1r; glucagon-like peptide 1 receptor [KO:K04581]
101831592  Gpr119; glucose-dependent insulinotropic receptor [KO:K08424]
101835340  Fshr; follicle-stimulating hormone receptor precursor [KO:K04247]
101827695  Npr1; atrial natriuretic peptide receptor 1 isoform X1 [KO:K12323] [EC:4.6.1.2]
101834728  Gnas; guanine nucleotide-binding protein G(s) subunit alpha [KO:K04632]
101834284  neuroendocrine secretory protein 55 [KO:K04632]
101823078  Edn1; endothelin-1 [KO:K16366]
101842555  Edn2; endothelin-2 [KO:K16367]
101837967  Edn3; endothelin-3 [KO:K05227]
101822745  Sst; somatostatin [KO:K05237]
101841245  Npy; pro-neuropeptide Y [KO:K05232]
101826236  Ghrl; appetite-regulating hormone isoform X1 [KO:K05254]
121140244  oxytocin-neurophysin 1-like [KO:K05243]
121140522  oxytocin-neurophysin 1-like [KO:K05243]
101823140  Htr1d; 5-hydroxytryptamine receptor 1D [KO:K04153]
101828602  Htr1a; 5-hydroxytryptamine receptor 1A [KO:K04153]
101827066  Htr1f; 5-hydroxytryptamine receptor 1F [KO:K04153]
101840272  Htr1b; 5-hydroxytryptamine receptor 1B [KO:K04153]
101828505  Chrm1; muscarinic acetylcholine receptor M1 [KO:K04129]
101844151  Chrm2; muscarinic acetylcholine receptor M2 [KO:K04130]
101823722  Drd2; D(2) dopamine receptor [KO:K04145]
101823351  Gabbr1; gamma-aminobutyric acid type B receptor subunit 1 isoform X1 [KO:K04615]
101829101  Gabbr2; gamma-aminobutyric acid type B receptor subunit 2 isoform X1 [KO:K04615]
101823380  Adora1; adenosine receptor A1 isoform X1 [KO:K04265]
101832204  Ednra; endothelin-1 receptor [KO:K04197]
101838563  Npy1r; neuropeptide Y receptor type 1 [KO:K04204]
101824516  Sstr1; somatostatin receptor type 1 [KO:K04217]
101831657  Sstr2; somatostatin receptor type 2 isoform X2 [KO:K04218]
101842186  Sstr5; somatostatin receptor type 5 [KO:K04221]
101827697  Hcar1; hydroxycarboxylic acid receptor 1 [KO:K08401]
106021990  Hcar2; hydroxycarboxylic acid receptor 2 [KO:K08402]
101835275  Ffar2; free fatty acid receptor 2 [KO:K04328]
101826981  Sucnr1; succinate receptor 1 [KO:K10042]
101837737  Ptger3; prostaglandin E2 receptor EP3 subtype isoform X1 [KO:K04260]
101833814  Oxtr; oxytocin receptor [KO:K04229]
101826609  Ghsr; growth hormone secretagogue receptor type 1 [KO:K04284]
101832028  Gnai2; guanine nucleotide-binding protein G(i) subunit alpha-2 [KO:K04630]
101831676  Gnai3; guanine nucleotide-binding protein G(i) subunit alpha-3 [KO:K04630]
101828746  Gnai1; guanine nucleotide-binding protein G(i) subunit alpha-1 [KO:K04630]
101822607  Adcy1; adenylate cyclase type 1 [KO:K08041] [EC:4.6.1.1]
101836580  Adcy2; adenylate cyclase type 2 isoform X2 [KO:K08042] [EC:4.6.1.1]
101844476  Adcy3; LOW QUALITY PROTEIN: adenylate cyclase type 3 [KO:K08043] [EC:4.6.1.1]
101841504  Adcy4; adenylate cyclase type 4 [KO:K08044] [EC:4.6.1.1]
101827234  Adcy5; adenylate cyclase type 5 [KO:K08045] [EC:4.6.1.1]
101835563  Adcy6; LOW QUALITY PROTEIN: adenylate cyclase type 6 [KO:K08046] [EC:4.6.1.1]
101839314  Adcy7; adenylate cyclase type 7 isoform X2 [KO:K08047] [EC:4.6.1.1]
101827170  Adcy8; adenylate cyclase type 8 isoform X1 [KO:K08048] [EC:4.6.1.1]
101842546  Adcy9; adenylate cyclase type 9 isoform X2 [KO:K08049] [EC:4.6.1.1]
101832361  Adcy10; adenylate cyclase type 10 [KO:K11265] [EC:4.6.1.1]
101826392  Cnga1; cGMP-gated cation channel alpha-1 [KO:K04948]
101823343  Cnga2; cyclic nucleotide-gated olfactory channel [KO:K04949]
101833600  Cnga3; cyclic nucleotide-gated cation channel alpha-3 [KO:K04950]
101827472  Cnga4; cyclic nucleotide-gated cation channel alpha-4 [KO:K04951]
101841738  cyclic nucleotide-gated cation channel beta-1 [KO:K04952]
101843736  Cngb3; LOW QUALITY PROTEIN: cyclic nucleotide-gated cation channel beta-3 [KO:K04953]
121135759  Calml6; calmodulin-like protein 6 [KO:K02183]
101825969  calmodulin-1-like [KO:K02183]
101840179  calmodulin-like protein 3 [KO:K02183]
101840457  calmodulin-4 [KO:K02183]
101823161  Calm3; calmodulin-3 [KO:K02183]
101832379  Calm2; calmodulin-2 [KO:K02183]
101828975  Calm1; calmodulin-1 [KO:K02183]
121136988  calmodulin-alpha-like [KO:K02183]
101834468  Calml4; calmodulin-like protein 4 [KO:K02183]
101833206  calmodulin-A-like [KO:K02183]
101830635  Camk2g; calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X5 [KO:K04515] [EC:2.7.11.17]
101833722  Camk2b; calcium/calmodulin-dependent protein kinase type II subunit beta isoform X13 [KO:K04515] [EC:2.7.11.17]
101833285  Camk2d; calcium/calmodulin-dependent protein kinase type II subunit delta isoform X1 [KO:K04515] [EC:2.7.11.17]
101841273  Camk2a; calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1 [KO:K04515] [EC:2.7.11.17]
101841141  Camk4; calcium/calmodulin-dependent protein kinase type IV isoform X2 [KO:K05869] [EC:2.7.11.17]
101840262  Bves; blood vessel epicardial substance [KO:K21108]
101835759  Popdc2; popeye domain-containing protein 2 isoform X1 [KO:K26206]
101840537  Popdc3; popeye domain-containing protein 3 [KO:K26207]
101834841  Kcnk2; potassium channel subfamily K member 2 isoform X1 [KO:K04913]
101843899  Hcn2; potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 isoform X1 [KO:K04955]
101833056  Hcn4; LOW QUALITY PROTEIN: potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 [KO:K04957]
101836554  Abcc4; multidrug resistance-associated protein 4 [KO:K05673]
101828520  Rapgef3; rap guanine nucleotide exchange factor 3 isoform X4 [KO:K08014]
101839349  Rapgef4; rap guanine nucleotide exchange factor 4 isoform X4 [KO:K04351]
101826841  Rras; ras-related protein R-Ras [KO:K07829]
101833340  Rras2; ras-related protein R-Ras2 [KO:K07830]
101842050  Pld2; phospholipase D2 [KO:K01115] [EC:3.1.4.4]
101827579  Pld1; phospholipase D1 isoform X1 [KO:K01115] [EC:3.1.4.4]
101832834  Plce1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X4 [KO:K05860] [EC:3.1.4.11]
101832187  Mapk9; mitogen-activated protein kinase 9 isoform X1 [KO:K04440] [EC:2.7.11.24]
101827071  Mapk8; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
101841730  Mapk10; mitogen-activated protein kinase 10 isoform X1 [KO:K04440] [EC:2.7.11.24]
101841364  Rap1a; ras-related protein Rap-1A isoform X1 [KO:K04353]
101823756  Rap1b; ras-related protein Rap-1b [KO:K07836]
101830242  Tiam1; T-lymphoma invasion and metastasis-inducing protein 1 isoform X1 [KO:K05731]
101829386  Vav2; guanine nucleotide exchange factor VAV2 isoform X6 [KO:K05730]
101838062  Vav3; guanine nucleotide exchange factor VAV3 isoform X2 [KO:K05730]
101822781  Vav1; proto-oncogene vav [KO:K05730]
101841113  Rac1; ras-related C3 botulinum toxin substrate 1 isoform X2 [KO:K04392]
101824666  Rac2; ras-related C3 botulinum toxin substrate 2 [KO:K07860]
101835840  Rac3; ras-related C3 botulinum toxin substrate 3 isoform X1 [KO:K07861]
101843056  Pak1; serine/threonine-protein kinase PAK 1 [KO:K04409] [EC:2.7.11.1]
101826958  Arap3; LOW QUALITY PROTEIN: arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 [KO:K12490]
101833518  transforming protein RhoA-like [KO:K04513]
101831918  Rhoa; transforming protein RhoA [KO:K04513]
101823227  Afdn; afadin isoform X1 [KO:K05702]
101823280  Pik3cb; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
101828739  Pik3cd; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X4 [KO:K00922] [EC:2.7.1.153]
101843471  Pik3ca; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
101829045  Pik3r2; phosphatidylinositol 3-kinase regulatory subunit beta isoform X2 [KO:K02649]
101835039  Pik3r1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
101831400  phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1 [KO:K02649]
101842312  Akt2; RAC-beta serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
101825464  Akt1; RAC-alpha serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
101840296  Akt3; RAC-gamma serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
101823512  Braf; serine/threonine-protein kinase B-raf isoform X1 [KO:K04365] [EC:2.7.11.1]
101843997  Raf1; RAF proto-oncogene serine/threonine-protein kinase isoform X2 [KO:K04366] [EC:2.7.11.1]
101831139  Map2k1; dual specificity mitogen-activated protein kinase kinase 1 isoform X1 [KO:K04368] [EC:2.7.12.2]
101822879  Map2k2; dual specificity mitogen-activated protein kinase kinase 2 isoform X1 [KO:K04369] [EC:2.7.12.2]
101825943  Mapk1; mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
101841668  Mapk3; LOW QUALITY PROTEIN: mitogen-activated protein kinase 3 [KO:K04371] [EC:2.7.11.24]
101841299  Prkacb; cAMP-dependent protein kinase catalytic subunit beta isoform X1 [KO:K04345] [EC:2.7.11.11]
101840885  Prkaca; cAMP-dependent protein kinase catalytic subunit alpha isoform X1 [KO:K04345] [EC:2.7.11.11]
101841550  Ppp1r1b; protein phosphatase 1 regulatory subunit 1B [KO:K15494]
101827540  Ppp1ca; serine/threonine-protein phosphatase PP1-alpha catalytic subunit [KO:K06269] [EC:3.1.3.16]
101825320  Ppp1cb; serine/threonine-protein phosphatase PP1-beta catalytic subunit [KO:K06269] [EC:3.1.3.16]
101843083  Ppp1cc; serine/threonine-protein phosphatase PP1-gamma catalytic subunit [KO:K06269] [EC:3.1.3.16]
101838929  Creb1; cyclic AMP-responsive element-binding protein 1 [KO:K05870]
101823321  Creb3l3; cyclic AMP-responsive element-binding protein 3-like protein 3 isoform X2 [KO:K09048]
101837749  Creb3l1; cyclic AMP-responsive element-binding protein 3-like protein 1 [KO:K09048]
101844692  Creb3l2; cyclic AMP-responsive element-binding protein 3-like protein 2 isoform X2 [KO:K09048]
101834652  Creb3; cyclic AMP-responsive element-binding protein 3 isoform X1 [KO:K09048]
101826865  Creb3l4; cyclic AMP-responsive element-binding protein 3-like protein 4 isoform X1 [KO:K09048]
101844837  Creb5; cyclic AMP-responsive element-binding protein 5 isoform X2 [KO:K09047]
101838297  Ep300; histone acetyltransferase p300 isoform X1 [KO:K04498] [EC:2.3.1.48]
101842987  CREB-binding protein isoform X1 [KO:K04498] [EC:2.3.1.48]
101837384  Bdnf; LOW QUALITY PROTEIN: brain-derived neurotrophic factor [KO:K04355]
101831721  Fos; proto-oncogene c-Fos [KO:K04379]
101829259  Jun; transcription factor AP-1 [KO:K04448]
101832795  Gli3; transcriptional activator GLI3 isoform X1 [KO:K06230]
101832916  Gli1; zinc finger protein GLI1 isoform X1 [KO:K16797]
101823482  Ptch1; protein patched homolog 1 isoform X1 [KO:K06225]
101828564  LOW QUALITY PROTEIN: hedgehog-interacting protein [KO:K06231]
101835014  Nfkbia; NF-kappa-B inhibitor alpha [KO:K04734]
101839499  Nfkb1; nuclear factor NF-kappa-B p105 subunit isoform X1 [KO:K02580]
101831177  Rela; transcription factor p65 isoform X1 [KO:K04735]
101832183  Sox9; transcription factor SOX-9 [KO:K18435]
101826563  Amh; muellerian-inhibiting factor isoform X1 [KO:K04665]
101827388  Ppara; peroxisome proliferator-activated receptor alpha [KO:K07294]
101838571  Acox1; peroxisomal acyl-coenzyme A oxidase 1 isoform X1 [KO:K00232] [EC:1.3.3.6]
101841437  Acox3; peroxisomal acyl-coenzyme A oxidase 3 isoform X1 [KO:K00232] [EC:1.3.3.6]
101844781  Nfatc1; nuclear factor of activated T-cells, cytoplasmic 1 isoform X1 [KO:K04446]
101844170  F2r; proteinase-activated receptor 1 [KO:K03914]
101836153  Bad; bcl2-associated agonist of cell death isoform X1 [KO:K02158]
101825806  Lipe; hormone-sensitive lipase isoform X3 [KO:K07188] [EC:3.1.1.79]
101843167  Rock1; rho-associated protein kinase 1 isoform X1 [KO:K04514] [EC:2.7.11.1]
101838535  Rock2; rho-associated protein kinase 2 isoform X1 [KO:K17388] [EC:2.7.11.1]
101822552  Ppp1r12a; protein phosphatase 1 regulatory subunit 12A isoform X1 [KO:K06270]
101837553  Myl9; myosin regulatory light polypeptide 9 [KO:K12755]
101830909  Tnni3; troponin I, cardiac muscle [KO:K12044]
101844657  Pln; cardiac phospholamban [KO:K05852]
101841211  Atp2a2; sarcoplasmic/endoplasmic reticulum calcium ATPase 2 [KO:K05853] [EC:7.2.2.10]
101828431  Atp2a3; sarcoplasmic/endoplasmic reticulum calcium ATPase 3 isoform X1 [KO:K05853] [EC:7.2.2.10]
101824306  Atp2a1; sarcoplasmic/endoplasmic reticulum calcium ATPase 1 isoform X1 [KO:K05853] [EC:7.2.2.10]
101841801  Ryr2; ryanodine receptor 2 isoform X1 [KO:K04962]
101827090  Grin1; glutamate receptor ionotropic, NMDA 1 isoform X1 [KO:K05208]
101824116  Grin2a; glutamate receptor ionotropic, NMDA 2A [KO:K05209]
101824692  Grin2b; glutamate receptor ionotropic, NMDA 2B [KO:K05210]
101826172  Grin2c; LOW QUALITY PROTEIN: glutamate receptor ionotropic, NMDA 2C [KO:K05211]
101822703  Grin2d; glutamate receptor ionotropic, NMDA 2D [KO:K05212]
101834481  Grin3a; glutamate receptor ionotropic, NMDA 3A [KO:K05213]
101838616  Grin3b; glutamate receptor ionotropic, NMDA 3B [KO:K05214]
101836867  Gria1; glutamate receptor 1 isoform X1 [KO:K05197]
101828199  Gria2; glutamate receptor 2 isoform X6 [KO:K05198]
101823120  Gria3; glutamate receptor 3 isoform X1 [KO:K05199]
101822769  Gria4; glutamate receptor 4 isoform X7 [KO:K05200]
101831516  Cftr; cystic fibrosis transmembrane conductance regulator [KO:K05031] [EC:5.6.1.6]
101828152  Atp1a3; LOW QUALITY PROTEIN: sodium/potassium-transporting ATPase subunit alpha-3 [KO:K01539] [EC:7.2.2.13]
101828029  Atp1a1; sodium/potassium-transporting ATPase subunit alpha-1 [KO:K01539] [EC:7.2.2.13]
101844313  Atp1a2; LOW QUALITY PROTEIN: sodium/potassium-transporting ATPase subunit alpha-2 [KO:K01539] [EC:7.2.2.13]
101844581  sodium/potassium-transporting ATPase subunit alpha-4 isoform X1 [KO:K01539] [EC:7.2.2.13]
101844422  Atp1b4; protein ATP1B4 [KO:K01540]
101828802  Atp1b1; sodium/potassium-transporting ATPase subunit beta-1 [KO:K01540]
101833660  Atp1b2; sodium/potassium-transporting ATPase subunit beta-2 [KO:K01540]
101836917  Atp1b3; sodium/potassium-transporting ATPase subunit beta-3 isoform X1 [KO:K01540]
106021095  Fxyd2; sodium/potassium-transporting ATPase subunit gamma isoform X1 [KO:K01538]
101832822  Fxyd1; phospholemman isoform X2 [KO:K13360]
101829817  Slc9a1; sodium/hydrogen exchanger 1 [KO:K05742]
101830091  Orai1; calcium release-activated calcium channel protein 1 [KO:K16056]
101825024  Atp2b2; plasma membrane calcium-transporting ATPase 2 isoform X1 [KO:K05850] [EC:7.2.2.10]
101840779  Atp2b3; plasma membrane calcium-transporting ATPase 3 isoform X5 [KO:K05850] [EC:7.2.2.10]
101838198  Atp2b1; plasma membrane calcium-transporting ATPase 1 isoform X1 [KO:K05850] [EC:7.2.2.10]
121136402  LOW QUALITY PROTEIN: plasma membrane calcium-transporting ATPase 4-like [KO:K05850] [EC:7.2.2.10]
101826619  Atp2b4; plasma membrane calcium-transporting ATPase 4 isoform X1 [KO:K05850] [EC:7.2.2.10]
121138665  plasma membrane calcium-transporting ATPase 4 isoform X1 [KO:K05850] [EC:7.2.2.10]
101834428  Cacna1c; voltage-dependent L-type calcium channel subunit alpha-1C isoform X23 [KO:K04850]
101825756  Cacna1d; voltage-dependent L-type calcium channel subunit alpha-1D [KO:K04851]
101830198  Cacna1f; voltage-dependent L-type calcium channel subunit alpha-1F [KO:K04853]
101835763  Cacna1s; voltage-dependent L-type calcium channel subunit alpha-1S isoform X1 [KO:K04857]
101830782  Pde3a; cGMP-inhibited 3',5'-cyclic phosphodiesterase A isoform X1 [KO:K19021] [EC:3.1.4.17]
101837973  Pde3b; cGMP-inhibited 3',5'-cyclic phosphodiesterase B [KO:K13296] [EC:3.1.4.17]
101825925  Pde4b; cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X4 [KO:K13293] [EC:3.1.4.53]
101823873  Pde4d; cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [KO:K13293] [EC:3.1.4.53]
101832298  Pde4a; LOW QUALITY PROTEIN: cAMP-specific 3',5'-cyclic phosphodiesterase 4A [KO:K13293] [EC:3.1.4.53]
101844613  Pde4c; LOW QUALITY PROTEIN: cAMP-specific 3',5'-cyclic phosphodiesterase 4C [KO:K13293] [EC:3.1.4.53]
101835622  Pde10a; cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A isoform X1 [KO:K18438] [EC:3.1.4.17 3.1.4.35]
Compound
C00020  AMP
C00042  Succinate
C00076  Calcium cation
C00080  H+
C00165  Diacylglycerol
C00186  (S)-Lactate
C00212  Adenosine
C00238  Potassium cation
C00288  HCO3-
C00334  4-Aminobutanoate
C00416  Phosphatidate
C00547  L-Noradrenaline
C00575  3',5'-Cyclic AMP
C00584  Prostaglandin E2
C00698  Cl-
C00780  Serotonin
C00788  L-Adrenaline
C01089  (R)-3-Hydroxybutanoate
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01312  Prostaglandin I2
C01330  Sodium cation
C01996  Acetylcholine
C03758  Dopamine
C20792  Oleoylethanolamide
C20793  3-Hydroxyoctanoate
Reference
PMID:11493633
  Authors
Fimia GM, Sassone-Corsi P
  Title
Cyclic AMP signalling.
  Journal
J Cell Sci 114:1971-2 (2001)
Reference
PMID:18323530
  Authors
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Related
pathway
maua00071  Fatty acid degradation
maua04015  Rap1 signaling pathway
maua04020  Calcium signaling pathway
maua04151  PI3K-Akt signaling pathway
maua04210  Apoptosis
maua04260  Cardiac muscle contraction
maua04340  Hedgehog signaling pathway
maua04720  Long-term potentiation
maua04740  Olfactory transduction
maua04972  Pancreatic secretion
maua04976  Bile secretion
KO pathway
ko04024   
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