KEGG   PATHWAY: mcal05167
Entry
mcal05167                   Pathway                                
Name
Kaposi sarcoma-associated herpesvirus infection - Mus caroli (Ryukyu mouse)
Description
Kaposi sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus 8 (HHV-8), is the most recently identified human tumor virus, and is associated with the pathogenesis of Kaposi's sarcoma (KS), primary effusion lymphoma (PEL), and Multicentric Castleman's disease (MCD). Like all other herpesviruses, KSHV displays two modes of life cycle, latency and lytic replication, which are characterized by the patterns of viral gene expression. Genes expressed in latency (LANA, v-cyclin, v-FLIP, Kaposins A, B and C and viral miRNAs) are mainly thought to facilitate the establishment of life long latency in its host and survival against the host innate, and adaptive immune surveillance mechanisms. Among the viral proteins shown to be expressed during lytic replication are potent signaling molecules such as vGPCR, vIL6, vIRFs, vCCLs, K1 and K15, which have been implicated experimentally in the angiogenic and inflammatory phenotype observed in KS lesions. Several of these latent viral and lytic proteins are known to transform host cells, linking KSHV with the development of severe human malignancies.
Class
Human Diseases; Infectious disease: viral
Pathway map
mcal05167  Kaposi sarcoma-associated herpesvirus infection
mcal05167

Organism
Mus caroli (Ryukyu mouse) [GN:mcal]
Gene
110312494  C3; complement C3 [KO:K03990]
110300361  Tlr3; toll-like receptor 3 [KO:K05401]
110283813  Ticam1; TIR domain-containing adapter molecule 1 [KO:K05842]
110306954  Traf3; TNF receptor-associated factor 3 [KO:K03174]
110301565  Ikbke; inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform X1 [KO:K07211] [EC:2.7.11.10]
110303265  Tbk1; serine/threonine-protein kinase TBK1 [KO:K05410] [EC:2.7.11.10]
110297922  Irf7; interferon regulatory factor 7 isoform X1 [KO:K09447]
110293074  interferon alpha-12 [KO:K05414]
110288626  interferon alpha-7 [KO:K05414]
110288627  interferon alpha-4 [KO:K05414]
110288628  interferon alpha-5-like [KO:K05414]
110292605  interferon alpha-11 [KO:K05414]
110293011  interferon alpha-12-like [KO:K05414]
110293017  interferon alpha-9 [KO:K05414]
110293025  interferon alpha-1-like [KO:K05414]
110292939  interferon alpha-9-like [KO:K05414]
110292945  interferon alpha-1-like [KO:K05414]
110292969  interferon alpha-9-like [KO:K05414]
110292975  interferon alpha-1 [KO:K05414]
110292981  interferon alpha-2-like [KO:K05414]
110298322  Irf3; interferon regulatory factor 3 [KO:K05411]
110310313  Ep300; LOW QUALITY PROTEIN: histone acetyltransferase p300 [KO:K04498] [EC:2.3.1.48]
110311224  Crebbp; CREB-binding protein isoform X1 [KO:K04498] [EC:2.3.1.48]
110293791  Ifnb1; interferon beta [KO:K05415]
110311756  Ifnar1; interferon alpha/beta receptor 1 [KO:K05130]
110311924  Ifnar2; interferon alpha/beta receptor 2 isoform X2 [KO:K05131]
110292243  Jak1; tyrosine-protein kinase JAK1 [KO:K11217] [EC:2.7.10.2]
110302481  Tyk2; non-receptor tyrosine-protein kinase TYK2 [KO:K11219] [EC:2.7.10.2]
110304843  Stat1; signal transducer and activator of transcription 1-alpha/beta isoform X1 [KO:K11220]
110302854  Stat2; signal transducer and activator of transcription 2 isoform X1 [KO:K11221]
110309049  Irf9; LOW QUALITY PROTEIN: interferon regulatory factor 9 [KO:K04693]
110312307  Eif2ak2; interferon-induced, double-stranded RNA-activated protein kinase [KO:K16195] [EC:2.7.11.1]
110312562  Mapk13; mitogen-activated protein kinase 13 [KO:K04441] [EC:2.7.11.24]
110310902  Mapk12; mitogen-activated protein kinase 12 [KO:K04441] [EC:2.7.11.24]
110310903  Mapk11; mitogen-activated protein kinase 11 isoform X2 [KO:K04441] [EC:2.7.11.24]
110312437  Mapk14; mitogen-activated protein kinase 14 isoform X1 [KO:K04441] [EC:2.7.11.24]
110294905  Mapkapk2; MAP kinase-activated protein kinase 2 isoform X1 [KO:K04443] [EC:2.7.11.1]
110304684  Map2k6; dual specificity mitogen-activated protein kinase kinase 6 isoform X1 [KO:K04433] [EC:2.7.12.2]
110298302  Zfp36; mRNA decay activator protein ZFP36 [KO:K15308]
110295330  Il6; interleukin-6 [KO:K05405]
110305989  Csf2; granulocyte-macrophage colony-stimulating factor [KO:K05427]
110302271  Ccr3; C-C chemokine receptor type 3 [KO:K04178]
110302023  C-C chemokine receptor type 5 [KO:K04180]
110302114  C-C chemokine receptor type 1 [KO:K04176]
110302544  C-C chemokine receptor 1-like protein 1 [KO:K04176]
110302548  Ccr4; C-C chemokine receptor type 4 [KO:K04179]
110302581  Ccr8; C-C chemokine receptor type 8 [KO:K04183]
110285655  Fas; tumor necrosis factor receptor superfamily member 6 isoform X1 [KO:K04390]
110298222  Fadd; FAS-associated death domain protein [KO:K02373]
110291975  Casp8; caspase-8 [KO:K04398] [EC:3.4.22.61]
110297919  Bax; apoptosis regulator BAX isoform X1 [KO:K02159]
110283660  Bak1; bcl-2 homologous antagonist/killer [KO:K14021]
110303728  cytochrome c, somatic-like [KO:K08738]
110309371  cytochrome c, testis-specific [KO:K08738]
110296815  cytochrome c, somatic [KO:K08738]
110293440  Casp9; caspase-9 [KO:K04399] [EC:3.4.22.62]
110299851  Casp3; caspase-3 [KO:K02187] [EC:3.4.22.56]
110296205  Tnfrsf1a; tumor necrosis factor receptor superfamily member 1A [KO:K03158]
110300541  Tradd; tumor necrosis factor receptor type 1-associated DEATH domain protein [KO:K03171]
110289986  Traf2; TNF receptor-associated factor 2 isoform X1 [KO:K03173] [EC:2.3.2.27]
110285285  Chuk; inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1 [KO:K04467] [EC:2.7.11.10]
110300158  Ikbkb; inhibitor of nuclear factor kappa-B kinase subunit beta [KO:K07209] [EC:2.7.11.10]
110287188  Ikbkg; NF-kappa-B essential modulator isoform X4 [KO:K07210]
110306864  Nfkbia; NF-kappa-B inhibitor alpha [KO:K04734]
110291231  Nfkb1; nuclear factor NF-kappa-B p105 subunit isoform X1 [KO:K02580]
110285703  Rela; transcription factor p65 [KO:K04735]
110305297  Tp53; cellular tumor antigen p53 isoform X1 [KO:K04451]
110283679  Cdkn1a; cyclin-dependent kinase inhibitor 1 [KO:K06625]
110303132  Cdk4; cyclin-dependent kinase 4 isoform X1 [KO:K02089] [EC:2.7.11.22]
110294345  Cdk6; cyclin-dependent kinase 6 [KO:K02091] [EC:2.7.11.22]
110309179  Rb1; retinoblastoma-associated protein [KO:K06618]
110289983  E2f1; transcription factor E2F1 [KO:K17454]
110293508  E2f2; transcription factor E2F2 isoform X1 [KO:K09389]
110308034  E2f3; transcription factor E2F3 isoform X1 [KO:K06620]
110287975  class I histocompatibility antigen, Gogo-A*0501 alpha chain-like isoform X1 [KO:K06751]
110312557  H-2 class I histocompatibility antigen, Q10 alpha chain-like isoform X1 [KO:K06751]
110283877  H-2 class I histocompatibility antigen, Q10 alpha chain-like [KO:K06751]
110288427  LOW QUALITY PROTEIN: H-2 class I histocompatibility antigen, K-B alpha chain-like [KO:K06751]
110288489  H-2 class I histocompatibility antigen, D-K alpha chain-like [KO:K06751]
110288539  LOW QUALITY PROTEIN: H-2 class I histocompatibility antigen, Q10 alpha chain-like [KO:K06751]
110312198  H-2 class I histocompatibility antigen, L-D alpha chain-like isoform X4 [KO:K06751]
110312199  H-2 class I histocompatibility antigen, D-B alpha chain-like isoform X1 [KO:K06751]
110312200  H-2 class I histocompatibility antigen, D-37 alpha chain [KO:K06751]
110312202  H-2 class I histocompatibility antigen, alpha chain-like isoform X1 [KO:K06751]
110312220  H-2 class I histocompatibility antigen, Q10 alpha chain-like [KO:K06751]
110312221  LOW QUALITY PROTEIN: H-2 class I histocompatibility antigen, Q10 alpha chain-like [KO:K06751]
110312222  H-2 class I histocompatibility antigen, TLA(B) alpha chain-like [KO:K06751]
110287620  H-2 class I histocompatibility antigen, D-B alpha chain isoform X1 [KO:K06751]
110287649  H-2 class I histocompatibility antigen, D-K alpha chain-like [KO:K06751]
110287664  HLA class I histocompatibility antigen, A-25 alpha chain-like isoform X1 [KO:K06751]
110289160  H-2 class I histocompatibility antigen, K-K alpha chain-like [KO:K06751]
110288607  HLA class I histocompatibility antigen, A-32 alpha chain-like [KO:K06751]
110288635  H-2 class I histocompatibility antigen, Q7 alpha chain-like isoform X1 [KO:K06751]
110283629  H-2 class I histocompatibility antigen, TLA(B) alpha chain isoform X1 [KO:K06751]
110283630  H-2 class I histocompatibility antigen, D-K alpha chain-like isoform X1 [KO:K06751]
110288692  H-2 class I histocompatibility antigen, Q7 alpha chain-like [KO:K06751]
110283690  class I histocompatibility antigen, Non-RT1.A alpha-1 chain-like isoform X3 [KO:K06751]
110283724  H-2 class I histocompatibility antigen, Q7 alpha chain-like [KO:K06751]
110283726  HLA class I histocompatibility antigen, A-25 alpha chain-like isoform X1 [KO:K06751]
110283727  HLA class I histocompatibility antigen, A-24 alpha chain-like isoform X1 [KO:K06751]
110283728  HLA class I histocompatibility antigen, B-15 alpha chain-like isoform X1 [KO:K06751]
110283729  HLA class I histocompatibility antigen, A-25 alpha chain-like isoform X1 [KO:K06751]
110283730  HLA class I histocompatibility antigen, A-24 alpha chain-like isoform X1 [KO:K06751]
110312399  H-2 class I histocompatibility antigen, Q9 alpha chain-like [KO:K06751]
110312424  H-2 class I histocompatibility antigen, D-B alpha chain-like isoform X2 [KO:K06751]
110288817  HLA class I histocompatibility antigen, A-25 alpha chain-like isoform X1 [KO:K06751]
110303040  Ifngr1; interferon gamma receptor 1 [KO:K05132]
110301325  Icam1; intercellular adhesion molecule 1 [KO:K06490]
110311303  Cd86; T-lymphocyte activation antigen CD86 isoform X1 [KO:K05413]
110299956  Uba52; ubiquitin-60S ribosomal protein L40 [KO:K02927]
110304504  ubiquitin-like [KO:K02927]
110293569  ubiquitin-like [KO:K02977]
110305141  Rps27a; ubiquitin-40S ribosomal protein S27a [KO:K02977]
110304706  Becn1; beclin-1 isoform X1 [KO:K08334]
110309163  Atg14; beclin 1-associated autophagy-related key regulator [KO:K17889]
110284734  Pik3c3; phosphatidylinositol 3-kinase catalytic subunit type 3 isoform X1 [KO:K00914] [EC:2.7.1.137]
110311422  Atg3; ubiquitin-like-conjugating enzyme ATG3 [KO:K08343]
110299884  Map1lc3b; microtubule-associated proteins 1A/1B light chain 3B [KO:K10435]
110308937  Map1lc3a; microtubule-associated proteins 1A/1B light chain 3A [KO:K10435]
110292306  Gnb1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 [KO:K04536]
110294718  Gnb2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 [KO:K04537]
110295995  Gnb3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 [KO:K07825]
110290992  Gnb4; guanine nucleotide-binding protein subunit beta-4 isoform X1 [KO:K04538]
110301552  Gnb5; guanine nucleotide-binding protein subunit beta-5 [KO:K04539]
110309306  Gng2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 [KO:K07826]
110285794  Gng3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 [KO:K04540]
110308267  Gng4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 [KO:K04541]
110291468  Gng5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 [KO:K04542]
110303682  Gng7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 [KO:K04543]
110299246  Gng8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 [KO:K04544]
110292758  Gng10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 [KO:K04545]
110296688  Gng11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 [KO:K04546]
110300627  Gng14; putative guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-14 [KO:K04347]
110296551  Gng12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 [KO:K04347]
110283696  Gng13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 [KO:K04547]
110296864  Gngt1; guanine nucleotide-binding protein G(T) subunit gamma-T1 [KO:K04548]
110305185  Gngt2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 [KO:K04549]
110297313  Hras; GTPase HRas isoform X2 [KO:K02833]
110296194  Kras; GTPase KRas isoform X1 [KO:K07827]
110290873  Nras; GTPase NRas [KO:K07828]
110296919  Raf1; RAF proto-oncogene serine/threonine-protein kinase isoform X1 [KO:K04366] [EC:2.7.11.1]
110301502  Map2k1; dual specificity mitogen-activated protein kinase kinase 1 [KO:K04368] [EC:2.7.12.2]
110303196  Map2k2; dual specificity mitogen-activated protein kinase kinase 2 isoform X1 [KO:K04369] [EC:2.7.12.2]
110297836  Mapk3; mitogen-activated protein kinase 3 [KO:K04371] [EC:2.7.11.24]
110311382  Mapk1; mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
110306746  Hif1a; hypoxia-inducible factor 1-alpha isoform X5 [KO:K08268]
110292423  Jun; transcription factor AP-1 [KO:K04448]
110307063  Fos; proto-oncogene c-Fos [KO:K04379]
110306848  Pik3cg; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform [KO:K21289] [EC:2.7.1.153]
110305901  Pik3r5; phosphoinositide 3-kinase regulatory subunit 5 [KO:K21290]
110304507  Pik3r6; phosphoinositide 3-kinase regulatory subunit 6 isoform X1 [KO:K21290]
110290798  Pik3ca; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
110292183  Pik3cd; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
110301355  Pik3cb; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
110308009  Pik3r1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
110299855  Pik3r2; phosphatidylinositol 3-kinase regulatory subunit beta isoform X1 [KO:K02649]
110292624  phosphatidylinositol 3-kinase regulatory subunit gamma [KO:K02649]
110297609  Akt2; RAC-beta serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
110294471  Akt3; RAC-gamma serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
110307022  Akt1; RAC-alpha serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
110292680  Mtor; serine/threonine-protein kinase mTOR [KO:K07203] [EC:2.7.11.1]
110312512  Prex1; phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein isoform X1 [KO:K12365]
110293965  Rac1; ras-related C3 botulinum toxin substrate 1 [KO:K04392]
110294148  Mapk10; mitogen-activated protein kinase 10 isoform X1 [KO:K04440] [EC:2.7.11.24]
110308920  Mapk8; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
110304169  Mapk9; mitogen-activated protein kinase 9 isoform X1 [KO:K04440] [EC:2.7.11.24]
110311781  cell surface glycoprotein CD200 receptor 3 isoform X2 [KO:K21668]
110311845  Cd200r1; cell surface glycoprotein CD200 receptor 1 isoform X1 [KO:K21668]
110311868  cell surface glycoprotein CD200 receptor 2 [KO:K21668]
110311921  cell surface glycoprotein CD200 receptor 5-like [KO:K21668]
110308005  Syk; tyrosine-protein kinase SYK [KO:K05855] [EC:2.7.10.2]
110310031  Src; proto-oncogene tyrosine-protein kinase Src isoform X1 [KO:K05704] [EC:2.7.10.2]
110309091  Hck; tyrosine-protein kinase HCK isoform X1 [KO:K08893] [EC:2.7.10.2]
110304803  Map2k4; dual specificity mitogen-activated protein kinase kinase 4 isoform X1 [KO:K04430] [EC:2.7.12.2]
110299603  Map2k7; dual specificity mitogen-activated protein kinase kinase 7 isoform X1 [KO:K04431] [EC:2.7.12.2]
110300336  Plcg2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform X1 [KO:K05859] [EC:3.1.4.11]
110290454  Plcg1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [KO:K01116] [EC:3.1.4.11]
110296867  Itpr1; inositol 1,4,5-trisphosphate receptor type 1 isoform X1 [KO:K04958]
110295833  Itpr2; inositol 1,4,5-trisphosphate receptor type 2 [KO:K04959]
110312193  Itpr3; inositol 1,4,5-trisphosphate receptor type 3 [KO:K04960]
110286675  calmodulin-alpha-like [KO:K02183]
110308577  Calml3; calmodulin-like protein 3 [KO:K02183]
110308601  calmodulin-4 [KO:K02183]
110286582  calmodulin [KO:K02183]
110306434  Calm1; calmodulin-1 [KO:K02183]
110302040  Calml4; calmodulin-like protein 4 isoform X2 [KO:K02183]
110297869  Calm3; calmodulin-3 [KO:K02183]
110294847  calmodulin-like [KO:K02183]
110312637  Calm2; calmodulin-2 [KO:K02183]
110309045  Ppp3cb; serine/threonine-protein phosphatase 2B catalytic subunit beta isoform isoform X1 [KO:K04348] [EC:3.1.3.16]
110309273  Ppp3cc; serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform isoform X1 [KO:K04348] [EC:3.1.3.16]
110290686  Ppp3ca; serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X2 [KO:K04348] [EC:3.1.3.16]
110304839  Ppp3r1; calcineurin subunit B type 1 [KO:K06268]
110293037  Ppp3r2; calcineurin subunit B type 2 [KO:K06268]
110284760  Nfatc1; nuclear factor of activated T-cells, cytoplasmic 1 isoform X2 [KO:K04446]
110308382  Nfatc2; nuclear factor of activated T-cells, cytoplasmic 2 isoform X1 [KO:K17332]
110299723  Nfatc3; nuclear factor of activated T-cells, cytoplasmic 3 isoform X1 [KO:K17333]
110309052  Nfatc4; nuclear factor of activated T-cells, cytoplasmic 4 isoform X1 [KO:K17334]
110292340  prostaglandin G/H synthase 2 [KO:K11987] [EC:1.14.99.1]
110288090  LOW QUALITY PROTEIN: prostaglandin G/H synthase 2-like [KO:K11987] [EC:1.14.99.1]
110288092  prostaglandin G/H synthase 2-like [KO:K11987] [EC:1.14.99.1]
110288093  prostaglandin G/H synthase 2-like [KO:K11987] [EC:1.14.99.1]
110294442  C-X-C motif chemokine 3 [KO:K05505]
110294443  growth-regulated alpha protein [KO:K05505]
110295209  C-X-C motif chemokine 2 [KO:K05505]
110311695  Rcan1; calcipressin-1 isoform X1 [KO:K17901]
110291557  Fgf2; fibroblast growth factor 2 [KO:K18497]
110284402  Vegfa; vascular endothelial growth factor A isoform X1 [KO:K05448]
110310626  Pdgfb; platelet-derived growth factor subunit B isoform X1 [KO:K17386]
110300338  Angpt2; angiopoietin-2 [KO:K05466]
110307804  Il6st; interleukin-6 receptor subunit beta [KO:K05060]
110285435  Jak2; tyrosine-protein kinase JAK2 [KO:K04447] [EC:2.7.10.2]
110306201  Stat3; signal transducer and activator of transcription 3 isoform X1 [KO:K04692]
110311365  Gsk3b; glycogen synthase kinase-3 beta isoform X2 [KO:K03083] [EC:2.7.11.26]
110301052  Ctnnb1; catenin beta-1 [KO:K02105]
110304948  Tcf7; transcription factor 7 isoform X2 [KO:K02620]
110296038  Tcf7l1; transcription factor 7-like 1 isoform X2 [KO:K04490]
110285273  Tcf7l2; transcription factor 7-like 2 isoform X5 [KO:K04491]
110290892  Lef1; lymphoid enhancer-binding factor 1 isoform X1 [KO:K04492]
110285614  Creb1; cyclic AMP-responsive element-binding protein 1 isoform X2 [KO:K05870]
110298189  Ccnd1; G1/S-specific cyclin-D1 isoform X1 [KO:K04503]
110310583  Myc; myc proto-oncogene protein [KO:K04377]
Compound
C00076  Calcium cation
C00165  Diacylglycerol
C00350  Phosphatidylethanolamine
C01245  D-myo-Inositol 1,4,5-trisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
Reference
PMID:22403573
  Authors
Lee HR, Brulois K, Wong L, Jung JU
  Title
Modulation of Immune System by Kaposi's Sarcoma-Associated Herpesvirus: Lessons from Viral Evasion Strategies.
  Journal
Front Microbiol 3:44 (2012)
DOI:10.3389/fmicb.2012.00044
Reference
PMID:18948197
  Authors
Liang C, Lee JS, Jung JU
  Title
Immune evasion in Kaposi's sarcoma-associated herpes virus associated oncogenesis.
  Journal
Semin Cancer Biol 18:423-36 (2008)
DOI:10.1016/j.semcancer.2008.09.003
Reference
PMID:21040832
  Authors
Cai Q, Verma SC, Lu J, Robertson ES
  Title
Molecular biology of Kaposi's sarcoma-associated herpesvirus and related oncogenesis.
  Journal
Adv Virus Res 78:87-142 (2010)
DOI:10.1016/B978-0-12-385032-4.00003-3
Reference
PMID:16760382
  Authors
Rezaee SA, Cunningham C, Davison AJ, Blackbourn DJ
  Title
Kaposi's sarcoma-associated herpesvirus immune modulation: an overview.
  Journal
J Gen Virol 87:1781-804 (2006)
DOI:10.1099/vir.0.81919-0
Reference
PMID:19230674
  Authors
Areste C, Blackbourn DJ
  Title
Modulation of the immune system by Kaposi's sarcoma-associated herpesvirus.
  Journal
Trends Microbiol 17:119-29 (2009)
DOI:10.1016/j.tim.2008.12.001
Reference
PMID:16905191
  Authors
Mark L, Spiller OB, Villoutreix BO, Blom AM
  Title
Kaposi's sarcoma-associated herpes virus complement control protein: KCP--complement inhibition and more.
  Journal
Mol Immunol 44:11-22 (2007)
DOI:10.1016/j.molimm.2006.06.018
Reference
PMID:11500830
  Authors
Weber KS, Grone HJ, Rocken M, Klier C, Gu S, Wank R, Proudfoot AE, Nelson PJ, Weber C
  Title
Selective recruitment of Th2-type cells and evasion from a cytotoxic immune response mediated by viral macrophage inhibitory protein-II.
  Journal
Eur J Immunol 31:2458-66 (2001)
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Manipulation of glycogen-synthase kinase-3 activity in KSHV-associated cancers.
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pathway
mcal04010  MAPK signaling pathway
mcal04064  NF-kappa B signaling pathway
mcal04110  Cell cycle
mcal04115  p53 signaling pathway
mcal04140  Autophagy - animal
mcal04144  Endocytosis
mcal04151  PI3K-Akt signaling pathway
mcal04210  Apoptosis
mcal04310  Wnt signaling pathway
mcal04610  Complement and coagulation cascades
mcal04620  Toll-like receptor signaling pathway
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KO pathway
ko05167   
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