KEGG   PATHWAY: pale04024
Entry
pale04024                   Pathway                                
Name
cAMP signaling pathway - Pteropus alecto (black flying fox)
Description
cAMP is one of the most common and universal second messengers, and its formation is promoted by adenylyl cyclase (AC) activation after ligation of G protein-coupled receptors (GPCRs) by ligands including hormones, neurotransmitters, and other signaling molecules. cAMP regulates pivotal physiologic processes including metabolism, secretion, calcium homeostasis, muscle contraction, cell fate, and gene transcription. cAMP acts directly on three main targets: protein kinase A (PKA), the exchange protein activated by cAMP (Epac), and cyclic nucleotide-gated ion channels (CNGCs). PKA modulates, via phosphorylation, a number of cellular substrates, including transcription factors, ion channels, transporters, exchangers, intracellular Ca2+ -handling proteins, and the contractile machinery. Epac proteins function as guanine nucleotide exchange factors (GEFs) for both Rap1 and Rap2. Various effector proteins, including adaptor proteins implicated in modulation of the actin cytoskeleton, regulators of G proteins of the Rho family, and phospholipases, relay signaling downstream from Rap.
Class
Environmental Information Processing; Signal transduction
Pathway map
pale04024  cAMP signaling pathway
pale04024

Other DBs
GO: 0019933
Organism
Pteropus alecto (black flying fox) [GN:pale]
Gene
102898768  VIP; VIP peptides isoform X1 [KO:K05264]
102889005  VIP peptides [KO:K05264]
102898593  VIP peptides-like [KO:K05264]
102888210  CRH; corticoliberin [KO:K05256]
102890788  CGA; glycoprotein hormones alpha chain [KO:K08522]
102884710  lutropin subunit beta [KO:K08521]
102895144  GPHA2; glycoprotein hormone alpha-2 [KO:K25483]
102898688  GPHB5; glycoprotein hormone beta-5 [KO:K25484]
102887106  TSHB; thyrotropin subunit beta [KO:K05251]
102881636  POMC; pro-opiomelanocortin [KO:K05228]
102887866  GCG; glucagon isoform X1 [KO:K05259]
102880715  GIP; gastric inhibitory polypeptide isoform X1 [KO:K05258]
102897414  FSHB; follitropin subunit beta [KO:K05250]
102881128  NPPA; natriuretic peptides A [KO:K12334]
102882083  ADCYAP1; pituitary adenylate cyclase-activating polypeptide [KO:K05262]
102880796  ADRB1; beta-1 adrenergic receptor [KO:K04141]
102882861  ADRB2; beta-2 adrenergic receptor [KO:K04142]
102897814  DRD1; D(1A) dopamine receptor [KO:K04144]
102891476  DRD5; D(1B) dopamine receptor [KO:K05840]
102886314  ADORA2A; LOW QUALITY PROTEIN: adenosine receptor A2a [KO:K04266]
102882116  HTR4; 5-hydroxytryptamine receptor 4 isoform X2 [KO:K04160]
102895204  HTR6; 5-hydroxytryptamine receptor 6 [KO:K04162]
102884861  PTGER2; prostaglandin E2 receptor EP2 subtype [KO:K04259]
102888820  ADCYAP1R1; pituitary adenylate cyclase-activating polypeptide type I receptor isoform X7 [KO:K04587]
102880972  VIPR2; vasoactive intestinal polypeptide receptor 2 [KO:K04590]
102878226  CRHR1; corticotropin-releasing factor receptor 1 isoform X1 [KO:K04578]
102888327  CRHR2; corticotropin-releasing factor receptor 2 [KO:K04579]
102892001  LHCGR; lutropin-choriogonadotropic hormone receptor [KO:K04248]
102879305  TSHR; thyrotropin receptor isoform X1 [KO:K04249]
102898827  MC2R; adrenocorticotropic hormone receptor [KO:K04200]
102880230  GLP1R; glucagon-like peptide 1 receptor [KO:K04581]
102889144  GIPR; gastric inhibitory polypeptide receptor [KO:K04580]
102891459  GPR119; glucose-dependent insulinotropic receptor [KO:K08424]
102891598  FSHR; follicle-stimulating hormone receptor isoform X1 [KO:K04247]
102879793  NPR1; LOW QUALITY PROTEIN: atrial natriuretic peptide receptor 1 [KO:K12323] [EC:4.6.1.2]
102889764  guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas [KO:K04632]
102884106  neuroendocrine secretory protein 55-like [KO:K04632]
102895320  EDN1; endothelin-1 [KO:K16366]
102881495  EDN2; endothelin-2 [KO:K16367]
102887980  SST; somatostatin [KO:K05237]
102878070  NPY; pro-neuropeptide Y [KO:K05232]
102891071  GHRL; appetite-regulating hormone [KO:K05254]
102897715  OXT; oxytocin-neurophysin 1 [KO:K05243]
102886462  HTR1D; 5-hydroxytryptamine receptor 1D [KO:K04153]
102893659  HTR1A; 5-hydroxytryptamine receptor 1A [KO:K04153]
102891031  HTR1E; 5-hydroxytryptamine receptor 1E [KO:K04153]
102878625  HTR1B; 5-hydroxytryptamine receptor 1B [KO:K04153]
102881524  HTR1F; 5-hydroxytryptamine receptor 1F [KO:K04153]
102885993  CHRM1; muscarinic acetylcholine receptor M1 [KO:K04129]
102883382  CHRM2; muscarinic acetylcholine receptor M2 [KO:K04130]
102883304  DRD2; D(2) dopamine receptor [KO:K04145]
102896532  GABBR1; gamma-aminobutyric acid type B receptor subunit 1 isoform X1 [KO:K04615]
102881192  GABBR2; gamma-aminobutyric acid type B receptor subunit 2 [KO:K04615]
102881697  ADORA1; adenosine receptor A1 [KO:K04265]
102898148  EDNRA; endothelin-1 receptor [KO:K04197]
102894502  NPY1R; neuropeptide Y receptor type 1 [KO:K04204]
102887676  SSTR1; somatostatin receptor type 1 [KO:K04217]
102887916  SSTR2; somatostatin receptor type 2 [KO:K04218]
102891462  SSTR5; somatostatin receptor type 5 [KO:K04221]
102879900  HCAR1; hydroxycarboxylic acid receptor 1 [KO:K08401]
102880145  hydroxycarboxylic acid receptor 2 [KO:K08402]
102880787  free fatty acid receptor 2 [KO:K04328]
102891682  SUCNR1; succinate receptor 1 [KO:K10042]
102890353  PTGER3; prostaglandin E2 receptor EP3 subtype isoform X1 [KO:K04260]
102879673  OXTR; oxytocin receptor [KO:K04229]
102885425  GHSR; growth hormone secretagogue receptor type 1 [KO:K04284]
102892785  GNAI3; guanine nucleotide-binding protein G(k) subunit alpha [KO:K04630]
102885642  GNAI1; guanine nucleotide-binding protein G(i) subunit alpha-1 [KO:K04630]
102898665  GNAI2; guanine nucleotide-binding protein G(i) subunit alpha-2 [KO:K04630]
102887497  ADCY1; adenylate cyclase type 1 [KO:K08041] [EC:4.6.1.1]
102893265  ADCY2; adenylate cyclase type 2 [KO:K08042] [EC:4.6.1.1]
102886232  ADCY3; adenylate cyclase type 3 [KO:K08043] [EC:4.6.1.1]
102890575  ADCY4; adenylate cyclase type 4 [KO:K08044] [EC:4.6.1.1]
102897495  ADCY5; adenylate cyclase type 5 [KO:K08045] [EC:4.6.1.1]
102890588  ADCY6; adenylate cyclase type 6 isoform X2 [KO:K08046] [EC:4.6.1.1]
102881535  ADCY7; adenylate cyclase type 7 [KO:K08047] [EC:4.6.1.1]
102896789  ADCY8; adenylate cyclase type 8 isoform X1 [KO:K08048] [EC:4.6.1.1]
102885676  ADCY9; adenylate cyclase type 9 [KO:K08049] [EC:4.6.1.1]
102889468  ADCY10; adenylate cyclase type 10 [KO:K11265] [EC:4.6.1.1]
102889521  CNGA1; cGMP-gated cation channel alpha-1 [KO:K04948]
102892553  CNGA2; cyclic nucleotide-gated olfactory channel [KO:K04949]
102895735  CNGA3; cyclic nucleotide-gated cation channel alpha-3 [KO:K04950]
102890337  CNGA4; cyclic nucleotide-gated cation channel alpha-4 isoform X2 [KO:K04951]
102885570  CNGB1; cyclic nucleotide-gated cation channel beta-1 [KO:K04952]
102896744  CNGB3; LOW QUALITY PROTEIN: cyclic nucleotide-gated cation channel beta-3 [KO:K04953]
102894226  CALM2; calmodulin-2 isoform X1 [KO:K02183]
102897273  CALM3; calmodulin-3 [KO:K02183]
102886058  CALM1; calmodulin-1 [KO:K02183]
102884196  CALML6; calmodulin-like protein 6 [KO:K02183]
102891673  calmodulin-like [KO:K02183]
102893109  CALML4; LOW QUALITY PROTEIN: calmodulin-like protein 4 [KO:K02183]
102881744  calmodulin-like [KO:K02183]
102888982  CAMK2B; calcium/calmodulin-dependent protein kinase type II subunit beta [KO:K04515] [EC:2.7.11.17]
102888385  CAMK2A; calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1 [KO:K04515] [EC:2.7.11.17]
102880869  CAMK2D; calcium/calmodulin-dependent protein kinase type II subunit delta [KO:K04515] [EC:2.7.11.17]
102896030  CAMK2G; calcium/calmodulin-dependent protein kinase type II subunit gamma [KO:K04515] [EC:2.7.11.17]
102879333  CAMK4; calcium/calmodulin-dependent protein kinase type IV [KO:K05869] [EC:2.7.11.17]
102885230  BVES; blood vessel epicardial substance [KO:K21108]
102881943  POPDC2; popeye domain-containing protein 2 [KO:K26206]
102885479  POPDC3; popeye domain-containing protein 3 [KO:K26207]
102885724  KCNK2; potassium channel subfamily K member 2 isoform X2 [KO:K04913]
102886947  HCN2; potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 [KO:K04955]
102893537  HCN4; potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 [KO:K04957]
102883988  ABCC4; multidrug resistance-associated protein 4 isoform X1 [KO:K05673]
102895678  RAPGEF3; rap guanine nucleotide exchange factor 3 isoform X2 [KO:K08014]
102884268  rap guanine nucleotide exchange factor 4 [KO:K04351]
102881941  RRAS; ras-related protein R-Ras [KO:K07829]
102881508  RRAS2; ras-related protein R-Ras2 [KO:K07830]
102884736  PLD1; phospholipase D1 isoform X1 [KO:K01115] [EC:3.1.4.4]
102894598  PLD2; phospholipase D2 isoform X1 [KO:K01115] [EC:3.1.4.4]
102898319  PLCE1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1 [KO:K05860] [EC:3.1.4.11]
102885064  MAPK10; mitogen-activated protein kinase 10 isoform X5 [KO:K04440] [EC:2.7.11.24]
102890689  MAPK9; mitogen-activated protein kinase 9 isoform X1 [KO:K04440] [EC:2.7.11.24]
102892777  MAPK8; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
102879271  RAP1A; ras-related protein Rap-1A [KO:K04353]
102883778  RAP1B; ras-related protein Rap-1b [KO:K07836]
102883973  TIAM1; LOW QUALITY PROTEIN: T-lymphoma invasion and metastasis-inducing protein 1 [KO:K05731]
102883521  VAV1; proto-oncogene vav [KO:K05730]
102886772  VAV3; guanine nucleotide exchange factor VAV3 [KO:K05730]
102884766  VAV2; guanine nucleotide exchange factor VAV2 [KO:K05730]
102897644  RAC1; ras-related C3 botulinum toxin substrate 1 isoform X1 [KO:K04392]
102885507  RAC2; ras-related C3 botulinum toxin substrate 2 [KO:K07860]
102887421  RAC3; ras-related C3 botulinum toxin substrate 3 [KO:K07861]
102880323  PAK1; LOW QUALITY PROTEIN: serine/threonine-protein kinase PAK 1 [KO:K04409] [EC:2.7.11.1]
102897313  ARAP3; arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X3 [KO:K12490]
102891515  RHOA; transforming protein RhoA [KO:K04513]
102891465  AFDN; afadin [KO:K05702]
102889227  PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
102880320  PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
102889576  PIK3CD; LOW QUALITY PROTEIN: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform [KO:K00922] [EC:2.7.1.153]
102879163  PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
102891637  phosphatidylinositol 3-kinase regulatory subunit gamma isoform X3 [KO:K02649]
102879453  PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta [KO:K02649]
102885144  AKT1; RAC-alpha serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
102879337  AKT3; RAC-gamma serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
102898305  AKT2; LOW QUALITY PROTEIN: RAC-beta serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
102878393  BRAF; serine/threonine-protein kinase B-raf isoform X2 [KO:K04365] [EC:2.7.11.1]
102893439  RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1 [KO:K04366] [EC:2.7.11.1]
102897122  MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 isoform X1 [KO:K04368] [EC:2.7.12.2]
102879034  MAP2K2; dual specificity mitogen-activated protein kinase kinase 2 [KO:K04369] [EC:2.7.12.2]
102895390  MAPK1; mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
102885749  MAPK3; mitogen-activated protein kinase 3 [KO:K04371] [EC:2.7.11.24]
102886679  PRKACA; cAMP-dependent protein kinase catalytic subunit alpha [KO:K04345] [EC:2.7.11.11]
102877853  PRKACB; cAMP-dependent protein kinase catalytic subunit beta isoform X1 [KO:K04345] [EC:2.7.11.11]
102886873  PPP1R1B; protein phosphatase 1 regulatory subunit 1B isoform X1 [KO:K15494]
102892254  PPP1CA; serine/threonine-protein phosphatase PP1-alpha catalytic subunit [KO:K06269] [EC:3.1.3.16]
102881448  PPP1CB; serine/threonine-protein phosphatase PP1-beta catalytic subunit [KO:K06269] [EC:3.1.3.16]
102887827  PPP1CC; serine/threonine-protein phosphatase PP1-gamma catalytic subunit [KO:K06269] [EC:3.1.3.16]
102888198  CREB1; cyclic AMP-responsive element-binding protein 1 isoform X1 [KO:K05870]
102878515  CREB3L4; cyclic AMP-responsive element-binding protein 3-like protein 4 [KO:K09048]
102894633  CREB3L1; cyclic AMP-responsive element-binding protein 3-like protein 1 isoform X1 [KO:K09048]
102882888  CREB3L2; cyclic AMP-responsive element-binding protein 3-like protein 2 isoform X1 [KO:K09048]
102886510  CREB3; cyclic AMP-responsive element-binding protein 3 isoform X1 [KO:K09048]
102879289  CREB3L3; cyclic AMP-responsive element-binding protein 3-like protein 3 [KO:K09048]
102884583  CREB5; cyclic AMP-responsive element-binding protein 5 isoform X1 [KO:K09047]
102886172  CREBBP; LOW QUALITY PROTEIN: CREB-binding protein [KO:K04498] [EC:2.3.1.48]
102881042  EP300; histone acetyltransferase p300 [KO:K04498] [EC:2.3.1.48]
102896087  BDNF; brain-derived neurotrophic factor isoform X1 [KO:K04355]
102891428  FOS; proto-oncogene c-Fos [KO:K04379]
102896121  JUN; transcription factor AP-1 [KO:K04448]
102894872  GLI3; transcriptional activator GLI3 isoform X1 [KO:K06230]
102889893  GLI1; zinc finger protein GLI1 isoform X1 [KO:K16797]
102884350  PTCH1; LOW QUALITY PROTEIN: protein patched homolog 1 [KO:K06225]
102880475  HHIP; hedgehog-interacting protein [KO:K06231]
102891056  NFKBIA; NF-kappa-B inhibitor alpha [KO:K04734]
102880692  NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1 [KO:K02580]
102878395  RELA; transcription factor p65 [KO:K04735]
102888164  SOX9; transcription factor SOX-9 [KO:K18435]
102893860  AMH; muellerian-inhibiting factor [KO:K04665]
102878006  PPARA; peroxisome proliferator-activated receptor alpha [KO:K07294]
102892373  ACOX3; peroxisomal acyl-coenzyme A oxidase 3 isoform X2 [KO:K00232] [EC:1.3.3.6]
102896015  ACOX1; peroxisomal acyl-coenzyme A oxidase 1 isoform X1 [KO:K00232] [EC:1.3.3.6]
102880857  NFATC1; nuclear factor of activated T-cells, cytoplasmic 1 isoform X1 [KO:K04446]
102886001  F2R; proteinase-activated receptor 1 [KO:K03914]
102877892  BAD; bcl2-associated agonist of cell death isoform X1 [KO:K02158]
102889858  LIPE; hormone-sensitive lipase isoform X1 [KO:K07188] [EC:3.1.1.79]
102879861  ROCK1; rho-associated protein kinase 1 isoform X1 [KO:K04514] [EC:2.7.11.1]
102897424  ROCK2; rho-associated protein kinase 2 [KO:K17388] [EC:2.7.11.1]
102898474  PPP1R12A; protein phosphatase 1 regulatory subunit 12A isoform X3 [KO:K06270]
102886777  MYL9; myosin regulatory light polypeptide 9 [KO:K12755]
102889585  TNNI3; troponin I, cardiac muscle isoform X1 [KO:K12044]
102885812  PLN; cardiac phospholamban [KO:K05852]
102885489  ATP2A2; sarcoplasmic/endoplasmic reticulum calcium ATPase 2 [KO:K05853] [EC:7.2.2.10]
102885534  ATP2A3; sarcoplasmic/endoplasmic reticulum calcium ATPase 3 [KO:K05853] [EC:7.2.2.10]
102884591  ATP2A1; sarcoplasmic/endoplasmic reticulum calcium ATPase 1 [KO:K05853] [EC:7.2.2.10]
102877858  RYR2; LOW QUALITY PROTEIN: ryanodine receptor 2 [KO:K04962]
102894415  GRIN1; glutamate receptor ionotropic, NMDA 1 [KO:K05208]
102898336  GRIN2A; glutamate receptor ionotropic, NMDA 2A [KO:K05209]
102882716  GRIN2B; glutamate receptor ionotropic, NMDA 2B [KO:K05210]
102881285  GRIN2C; LOW QUALITY PROTEIN: glutamate receptor ionotropic, NMDA 2C [KO:K05211]
102887718  GRIN2D; glutamate receptor ionotropic, NMDA 2D [KO:K05212]
102895744  GRIN3A; glutamate receptor ionotropic, NMDA 3A isoform X2 [KO:K05213]
102889943  GRIN3B; LOW QUALITY PROTEIN: glutamate receptor ionotropic, NMDA 3B [KO:K05214]
102897005  GRIA1; glutamate receptor 1 isoform X1 [KO:K05197]
102891151  GRIA2; glutamate receptor 2 isoform X1 [KO:K05198]
102892117  LOW QUALITY PROTEIN: glutamate receptor 3 [KO:K05199]
102887651  GRIA4; glutamate receptor 4 isoform X1 [KO:K05200]
102884577  CFTR; cystic fibrosis transmembrane conductance regulator [KO:K05031] [EC:5.6.1.6]
102893697  ATP1A3; sodium/potassium-transporting ATPase subunit alpha-3 [KO:K01539] [EC:7.2.2.13]
102884868  ATP1A4; sodium/potassium-transporting ATPase subunit alpha-4 [KO:K01539] [EC:7.2.2.13]
102885125  sodium/potassium-transporting ATPase subunit alpha-2 [KO:K01539] [EC:7.2.2.13]
102888359  ATP1A1; sodium/potassium-transporting ATPase subunit alpha-1 [KO:K01539] [EC:7.2.2.13]
102891547  ATP1B4; protein ATP1B4 isoform X1 [KO:K01540]
102894054  ATP1B1; sodium/potassium-transporting ATPase subunit beta-1 [KO:K01540]
102889357  ATP1B2; sodium/potassium-transporting ATPase subunit beta-2 [KO:K01540]
102896850  ATP1B3; sodium/potassium-transporting ATPase subunit beta-3 [KO:K01540]
102891289  FXYD2; sodium/potassium-transporting ATPase subunit gamma isoform X2 [KO:K01538]
102877856  FXYD1; phospholemman [KO:K13360]
102888463  SLC9A1; sodium/hydrogen exchanger 1 [KO:K05742]
102883130  ORAI1; calcium release-activated calcium channel protein 1 isoform X1 [KO:K16056]
102885387  ATP2B1; plasma membrane calcium-transporting ATPase 1 isoform X2 [KO:K05850] [EC:7.2.2.10]
102889420  ATP2B2; plasma membrane calcium-transporting ATPase 2 isoform X1 [KO:K05850] [EC:7.2.2.10]
102878692  ATP2B4; plasma membrane calcium-transporting ATPase 4 isoform X1 [KO:K05850] [EC:7.2.2.10]
102883154  ATP2B3; plasma membrane calcium-transporting ATPase 3 isoform X1 [KO:K05850] [EC:7.2.2.10]
102882682  CACNA1C; voltage-dependent L-type calcium channel subunit alpha-1C isoform X2 [KO:K04850]
102888351  CACNA1D; voltage-dependent L-type calcium channel subunit alpha-1D [KO:K04851]
102893611  CACNA1F; voltage-dependent L-type calcium channel subunit alpha-1F isoform X1 [KO:K04853]
102896136  CACNA1S; voltage-dependent L-type calcium channel subunit alpha-1S [KO:K04857]
102888167  PDE3A; cGMP-inhibited 3',5'-cyclic phosphodiesterase A isoform X1 [KO:K19021] [EC:3.1.4.17]
102894289  PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B [KO:K13296] [EC:3.1.4.17]
102898973  PDE4D; cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X4 [KO:K13293] [EC:3.1.4.53]
102895121  PDE4A; cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform X1 [KO:K13293] [EC:3.1.4.53]
102883499  PDE4B; cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1 [KO:K13293] [EC:3.1.4.53]
102883433  PDE4C; cAMP-specific 3',5'-cyclic phosphodiesterase 4C [KO:K13293] [EC:3.1.4.53]
102889492  PDE10A; cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A [KO:K18438] [EC:3.1.4.17 3.1.4.35]
Compound
C00020  AMP
C00042  Succinate
C00076  Calcium cation
C00080  H+
C00165  Diacylglycerol
C00186  (S)-Lactate
C00212  Adenosine
C00238  Potassium cation
C00288  HCO3-
C00334  4-Aminobutanoate
C00416  Phosphatidate
C00547  L-Noradrenaline
C00575  3',5'-Cyclic AMP
C00584  Prostaglandin E2
C00698  Cl-
C00780  Serotonin
C00788  L-Adrenaline
C01089  (R)-3-Hydroxybutanoate
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01312  Prostaglandin I2
C01330  Sodium cation
C01996  Acetylcholine
C03758  Dopamine
C20792  Oleoylethanolamide
C20793  3-Hydroxyoctanoate
Reference
PMID:11493633
  Authors
Fimia GM, Sassone-Corsi P
  Title
Cyclic AMP signalling.
  Journal
J Cell Sci 114:1971-2 (2001)
Reference
PMID:18323530
  Authors
Serezani CH, Ballinger MN, Aronoff DM, Peters-Golden M
  Title
Cyclic AMP: master regulator of innate immune cell function.
  Journal
Am J Respir Cell Mol Biol 39:127-32 (2008)
DOI:10.1165/rcmb.2008-0091TR
Reference
PMID:24281338
  Authors
Oldenburger A, Maarsingh H, Schmidt M
  Title
Multiple facets of cAMP signalling and physiological impact: cAMP compartmentalization in the lung.
  Journal
Pharmaceuticals (Basel) 5:1291-331 (2012)
DOI:10.3390/ph5121291
Reference
PMID:24613710
  Authors
Ahuja M, Jha A, Maleth J, Park S, Muallem S
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Related
pathway
pale00071  Fatty acid degradation
pale04015  Rap1 signaling pathway
pale04020  Calcium signaling pathway
pale04151  PI3K-Akt signaling pathway
pale04210  Apoptosis
pale04260  Cardiac muscle contraction
pale04340  Hedgehog signaling pathway
pale04720  Long-term potentiation
pale04740  Olfactory transduction
pale04972  Pancreatic secretion
pale04976  Bile secretion
KO pathway
ko04024   
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