KEGG   PATHWAY: pteh05162
Entry
pteh05162                   Pathway                                
Name
Measles - Piliocolobus tephrosceles (Ugandan red Colobus)
Description
Measles virus (MV) is highly contagious virus that leads infant death worldwide. Humans are the unique natural reservoir for this virus. MV infection is characterized by virus-induced immune suppression that can lead to increased susceptibility to secondary bacterial and viral infections. The P, V and C proteins act as virulence factors to suppress innate immune response in host by inhibiting signaling for both type I IFN induction and JAK/STAT-mediated interferon-stimulated gene (ISG) induction. Moreover,  H protein expressed on viral particles and binding to SLAM or CD46,  as well as N protein liberated from infected cells and interacting with Fc-gamma R, causes an inhibition of IL-12 synthesis in dendritic cells. IL-12 is a key cytokine inducing cellular immune responses to protect host from the harm caused by pathogenic infections.
Class
Human Diseases; Infectious disease: viral
Pathway map
pteh05162  Measles
pteh05162

Organism
Piliocolobus tephrosceles (Ugandan red Colobus) [GN:pteh]
Gene
111531166  membrane cofactor protein isoform X1 [KO:K04007]
113225220  LOW QUALITY PROTEIN: membrane cofactor protein-like [KO:K04007]
111531189  MSN; moesin [KO:K05763]
111543880  SLAMF1; signaling lymphocytic activation molecule isoform X1 [KO:K06536]
113223271  CD209 antigen-like protein 2 [KO:K06563]
113223273  CD209 antigen-like protein 2 [KO:K06563]
113219586  CD209 antigen-like protein 2 [KO:K06563]
113223276  CD209 antigen-like protein 2 [KO:K06563]
111522618  LOW QUALITY PROTEIN: CD209 antigen [KO:K06563]
111537232  DDX58; probable ATP-dependent RNA helicase DDX58 isoform X1 [KO:K12646] [EC:5.6.2.6]
111546062  IFIH1; interferon-induced helicase C domain-containing protein 1 isoform X1 [KO:K12647] [EC:5.6.2.6]
111548059  MAVS; mitochondrial antiviral-signaling protein isoform X1 [KO:K12648]
111538162  TRAF3; TNF receptor-associated factor 3 isoform X1 [KO:K03174]
111522719  IKBKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform X1 [KO:K07211] [EC:2.7.11.10]
111551230  TBK1; serine/threonine-protein kinase TBK1 [KO:K05410] [EC:2.7.11.10]
111539247  serine/threonine-protein kinase TBK1-like [KO:K05410] [EC:2.7.11.10]
111519959  IRF3; interferon regulatory factor 3 isoform X1 [KO:K05411]
111538794  CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1 [KO:K04467] [EC:2.7.11.10]
111544093  IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1 [KO:K07209] [EC:2.7.11.10]
111554041  NFKBIB; NF-kappa-B inhibitor beta isoform X1 [KO:K02581]
111524454  NFKBIA; NF-kappa-B inhibitor alpha [KO:K04734]
111547971  NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1 [KO:K02580]
111522422  RELA; transcription factor p65 isoform X1 [KO:K04735]
111531682  TLR7; toll-like receptor 7 isoform X1 [KO:K05404]
111528754  toll-like receptor 9 isoform X1 [KO:K10161]
111523175  MYD88; myeloid differentiation primary response protein MyD88 isoform X1 [KO:K04729]
111531307  IRAK1; interleukin-1 receptor-associated kinase 1 [KO:K04730] [EC:2.7.11.1]
111520209  IRAK4; interleukin-1 receptor-associated kinase 4 isoform X1 [KO:K04733] [EC:2.7.11.1]
111520580  IRF7; interferon regulatory factor 7 isoform X1 [KO:K09447]
111537187  interferon alpha-14 [KO:K05414]
111537188  interferon alpha-6 [KO:K05414]
111537189  interferon alpha-2 [KO:K05414]
111537190  interferon alpha-8 [KO:K05414]
111537191  interferon alpha-1/13 [KO:K05414]
111526141  interferon alpha-10 [KO:K05414]
111526147  IFNB1; interferon beta [KO:K05415]
111553190  TLR2; toll-like receptor 2 [KO:K10159]
111550322  TLR4; toll-like receptor 4 [KO:K10160]
111521878  TRAF6; TNF receptor-associated factor 6 [KO:K03175] [EC:2.3.2.27]
111541300  CSNK2A2; casein kinase II subunit alpha' [KO:K03097] [EC:2.7.11.1]
111548112  CSNK2A1; casein kinase II subunit alpha [KO:K03097] [EC:2.7.11.1]
111523947  CSNK2B; casein kinase II subunit beta isoform X1 [KO:K03115]
111525526  TNFAIP3; tumor necrosis factor alpha-induced protein 3 [KO:K11859] [EC:3.4.19.12]
111538092  MAP3K7; mitogen-activated protein kinase kinase kinase 7 isoform X1 [KO:K04427] [EC:2.7.11.25]
111523666  TAB2; TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 isoform X1 [KO:K04404]
111530867  MAPK10; mitogen-activated protein kinase 10 isoform X1 [KO:K04440] [EC:2.7.11.24]
111535725  MAPK9; mitogen-activated protein kinase 9 isoform X1 [KO:K04440] [EC:2.7.11.24]
111554538  MAPK8; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
111523160  JUN; transcription factor AP-1 [KO:K04448]
111521118  FOS; proto-oncogene c-Fos [KO:K04379]
111528223  IL1A; interleukin-1 alpha [KO:K04383]
111528224  IL1B; interleukin-1 beta [KO:K04519]
111545050  IL6; interleukin-6 isoform X1 [KO:K05405]
111550126  IL12A; interleukin-12 subunit alpha [KO:K05406]
111547191  IL12B; interleukin-12 subunit beta [KO:K05425]
111525309  IFNAR1; interferon alpha/beta receptor 1 isoform X1 [KO:K05130]
111525288  IFNAR2; interferon alpha/beta receptor 2 isoform X1 [KO:K05131]
111535498  RACK1; receptor of activated protein C kinase 1 [KO:K14753]
111541367  JAK1; tyrosine-protein kinase JAK1 isoform X1 [KO:K11217] [EC:2.7.10.2]
111527746  TYK2; non-receptor tyrosine-protein kinase TYK2 [KO:K11219] [EC:2.7.10.2]
111546340  STAT1; signal transducer and activator of transcription 1-alpha/beta [KO:K11220]
111541846  STAT2; signal transducer and activator of transcription 2 isoform X1 [KO:K11221]
111552934  IRF9; interferon regulatory factor 9 [KO:K04693]
111537215  OAS1; 2'-5'-oligoadenylate synthase 1 [KO:K14216] [EC:2.7.7.84]
111537227  OAS3; 2'-5'-oligoadenylate synthase 3 [KO:K14216] [EC:2.7.7.84]
111537233  OAS2; 2'-5'-oligoadenylate synthase 2 [KO:K14216] [EC:2.7.7.84]
111543727  ADAR; LOW QUALITY PROTEIN: double-stranded RNA-specific adenosine deaminase [KO:K12968] [EC:3.5.4.37]
111526193  MX2; interferon-induced GTP-binding protein Mx2 isoform X1 [KO:K14754]
111526222  MX1; interferon-induced GTP-binding protein Mx1 [KO:K14754]
111530515  EIF2AK1; eukaryotic translation initiation factor 2-alpha kinase 1 isoform X1 [KO:K16194] [EC:2.7.11.1]
111545386  EIF2AK2; interferon-induced, double-stranded RNA-activated protein kinase isoform X1 [KO:K16195] [EC:2.7.11.1]
111528197  EIF2AK3; eukaryotic translation initiation factor 2-alpha kinase 3 isoform X1 [KO:K08860] [EC:2.7.11.1]
111524249  EIF2AK4; eIF-2-alpha kinase GCN2 isoform X1 [KO:K16196] [EC:2.7.11.1]
111531666  RAB9A; ras-related protein Rab-9A [KO:K07899]
111535134  RAB9B; ras-related protein Rab-9B [KO:K07900]
113222861  heat shock 70 kDa protein 1 [KO:K03283]
111523910  heat shock 70 kDa protein 1 [KO:K03283]
111525033  HSPA6; LOW QUALITY PROTEIN: heat shock 70 kDa protein 6 [KO:K03283]
111523908  heat shock 70 kDa protein 1 [KO:K03283]
111523909  heat shock 70 kDa protein 1-like [KO:K03283]
111540268  HSPA8; heat shock cognate 71 kDa protein [KO:K03283]
111551065  EIF3H; eukaryotic translation initiation factor 3 subunit H [KO:K03247]
111519917  EIF2S1; eukaryotic translation initiation factor 2 subunit 1 [KO:K03237]
111524565  RCHY1; RING finger and CHY zinc finger domain-containing protein 1 isoform X1 [KO:K10144] [EC:2.3.2.27]
111527100  TP53; cellular tumor antigen p53 isoform X1 [KO:K04451]
111544596  TP73; tumor protein p73 isoform X1 [KO:K10148]
111520160  bcl-2-binding component 3, isoforms 1/2 [KO:K10132]
111539343  FASLG; tumor necrosis factor ligand superfamily member 6 [KO:K04389]
111551313  FAS; tumor necrosis factor receptor superfamily member 6 isoform X1 [KO:K04390]
111541333  TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein isoform X1 [KO:K03171]
111522332  FADD; FAS-associated death domain protein [KO:K02373]
111547169  CASP8; caspase-8 isoform X1 [KO:K04398] [EC:3.4.22.61]
111527587  BID; BH3-interacting domain death agonist isoform X1 [KO:K04726]
111520083  BAX; apoptosis regulator BAX isoform X1 [KO:K02159]
111542928  BAK1; bcl-2 homologous antagonist/killer [KO:K14021]
111528437  BCL2; apoptosis regulator Bcl-2 isoform X1 [KO:K02161]
111548123  BCL2L1; bcl-2-like protein 1 isoform X1 [KO:K04570]
111522294  BAD; bcl2-associated agonist of cell death [KO:K02158]
111528103  cytochrome c-like [KO:K08738]
111541425  cytochrome c [KO:K08738]
111551227  cytochrome c-like [KO:K08738]
111551298  cytochrome c-like [KO:K08738]
111551797  cytochrome c [KO:K08738]
111551867  cytochrome c [KO:K08738]
111543337  cytochrome c-like [KO:K08738]
111543628  cytochrome c-like [KO:K08738]
111534452  cytochrome c-like [KO:K08738]
111545049  cytochrome c-like [KO:K08738]
111555014  cytochrome c-like [KO:K08738]
111524229  cytochrome c [KO:K08738]
111525268  cytochrome c-like [KO:K08738]
111539464  cytochrome c-like [KO:K08738]
111526887  cytochrome c-like [KO:K08738]
111540111  cytochrome c-like [KO:K08738]
111520510  APAF1; apoptotic protease-activating factor 1 isoform X1 [KO:K02084]
111527287  CASP9; caspase-9 isoform X1 [KO:K04399] [EC:3.4.22.62]
111551382  caspase-3-like isoform X1 [KO:K02187] [EC:3.4.22.56]
111548479  CASP3; caspase-3 isoform X1 [KO:K02187] [EC:3.4.22.56]
111552085  CDKN1B; cyclin-dependent kinase inhibitor 1B isoform X1 [KO:K06624]
111522272  CCND1; G1/S-specific cyclin-D1 [KO:K04503]
111535839  CCND2; G1/S-specific cyclin-D2 [KO:K10151]
111543039  CCND3; G1/S-specific cyclin-D3 isoform X1 [KO:K10152]
111553938  CCNE1; G1/S-specific cyclin-E1 isoform X1 [KO:K06626]
111549709  CCNE2; G1/S-specific cyclin-E2 isoform X1 [KO:K06626]
111541790  CDK4; cyclin-dependent kinase 4 [KO:K02089] [EC:2.7.11.22]
111552475  CDK6; cyclin-dependent kinase 6 [KO:K02091] [EC:2.7.11.22]
111541872  CDK2; cyclin-dependent kinase 2 [KO:K02206] [EC:2.7.11.22]
113223191  uncharacterized protein LOC113223191 [KO:K10785]
113223192  uncharacterized protein LOC113223192 [KO:K10785]
113223196  uncharacterized protein LOC113223196 [KO:K10785]
113223197  uncharacterized protein LOC113223197 [KO:K10785]
113223207  uncharacterized protein LOC113223207 [KO:K10785]
113223208  uncharacterized protein LOC113223208 [KO:K10785]
113223211  uncharacterized protein LOC113223211 [KO:K10785]
113223212  uncharacterized protein LOC113223212 [KO:K10785]
111540206  CD3D; T-cell surface glycoprotein CD3 delta chain isoform X1 [KO:K06450]
111540204  CD3E; T-cell surface glycoprotein CD3 epsilon chain [KO:K06451]
111540205  CD3G; T-cell surface glycoprotein CD3 gamma chain [KO:K06452]
111547516  CD28; T-cell-specific surface glycoprotein CD28 isoform X1 [KO:K06470]
111546287  IL2; interleukin-2 [KO:K05429]
111554868  IL2RA; interleukin-2 receptor subunit alpha isoform X1 [KO:K05068]
111549045  IL2RB; interleukin-2 receptor subunit beta isoform X1 [KO:K05069]
111533635  IL2RG; cytokine receptor common subunit gamma [KO:K05070]
111554247  PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta [KO:K02649]
111539891  PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
111548774  PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma [KO:K02649]
111521403  PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
111544647  PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
111523340  PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
111542832  CBLB; E3 ubiquitin-protein ligase CBL-B isoform X1 [KO:K22517] [EC:2.3.2.27]
111554120  AKT2; RAC-beta serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
111545216  AKT3; RAC-gamma serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
111538340  AKT1; RAC-alpha serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
111543871  GSK3B; glycogen synthase kinase-3 beta isoform X1 [KO:K03083] [EC:2.7.11.26]
111554242  JAK3; tyrosine-protein kinase JAK3 isoform X1 [KO:K11218] [EC:2.7.10.2]
111537369  signal transducer and activator of transcription 3 isoform X1 [KO:K04692]
111537370  STAT5A; signal transducer and activator of transcription 5A [KO:K11223]
111537374  STAT5B; signal transducer and activator of transcription 5B isoform X1 [KO:K11224]
111533804  FCGR2B; low affinity immunoglobulin gamma Fc region receptor II-b isoform X2 [KO:K12560]
Compound
C05981  Phosphatidylinositol-3,4,5-trisphosphate
Reference
PMID:19203113
  Authors
Schneider-Schaulies S, Schneider-Schaulies J
  Title
Measles virus-induced immunosuppression.
  Journal
Curr Top Microbiol Immunol 330:243-69 (2009)
DOI:10.1007/978-3-540-70617-5_12
Reference
PMID:19203114
  Authors
Hahm B
  Title
Hostile communication of measles virus with host innate immunity and dendritic cells.
  Journal
Curr Top Microbiol Immunol 330:271-87 (2009)
DOI:10.1007/978-3-540-70617-5_13
Reference
PMID:19198566
  Authors
Gerlier D, Valentin H
  Title
Measles virus interaction with host cells and impact on innate immunity.
  Journal
Curr Top Microbiol Immunol 329:163-91 (2009)
DOI:10.1007/978-3-540-70523-9_8
Reference
PMID:16690907
  Authors
Schneider-Schaulies S, Dittmer U
  Title
Silencing T cells or T-cell silencing: concepts in virus-induced immunosuppression.
  Journal
J Gen Virol 87:1423-38 (2006)
DOI:10.1099/vir.0.81713-0
Reference
PMID:22049305
  Authors
Avota E, Gassert E, Schneider-Schaulies S
  Title
Cytoskeletal dynamics: concepts in measles virus replication and immunomodulation.
  Journal
Viruses 3:102-17 (2011)
DOI:10.3390/v3020102
Reference
PMID:27854326
  Authors
Jiang Y, Qin Y, Chen M
  Title
Host-Pathogen Interactions in Measles Virus Replication and Anti-Viral Immunity.
  Journal
Viruses 8:E308 (2016)
DOI:10.3390/v8110308
Reference
PMID:18922877
  Authors
Pfaller CK, Conzelmann KK
  Title
Measles virus V protein is a decoy substrate for IkappaB kinase alpha and prevents Toll-like receptor 7/9-mediated interferon induction.
  Journal
J Virol 82:12365-73 (2008)
DOI:10.1128/JVI.01321-08
Reference
PMID:17720800
  Authors
Yokota S, Okabayashi T, Yokosawa N, Fujii N
  Title
Measles virus P protein suppresses Toll-like receptor signal through up-regulation of ubiquitin-modifying enzyme A20.
  Journal
FASEB J 22:74-83 (2008)
DOI:10.1096/fj.07-8976com
Reference
PMID:23146309
  Authors
Delpeut S, Noyce RS, Siu RW, Richardson CD
  Title
Host factors and measles virus replication.
  Journal
Curr Opin Virol 2:773-83 (2012)
DOI:10.1016/j.coviro.2012.10.008
Reference
PMID:26878224
  Authors
Shah M, Anwar MA, Kim JH, Choi S
  Title
Advances in Antiviral Therapies Targeting Toll-like Receptors.
  Journal
Expert Opin Investig Drugs 25:437-53 (2016)
DOI:10.1517/13543784.2016.1154040
Reference
PMID:12620806
  Authors
Yokota S, Saito H, Kubota T, Yokosawa N, Amano K, Fujii N
  Title
Measles virus suppresses interferon-alpha signaling pathway: suppression of Jak1 phosphorylation and association of viral accessory proteins, C and V, with interferon-alpha receptor complex.
  Journal
Virology 306:135-46 (2003)
DOI:10.1016/S0042-6822(02)00026-0
Reference
PMID:12804771
  Authors
Takeuchi K, Kadota SI, Takeda M, Miyajima N, Nagata K
  Title
Measles virus V protein blocks interferon (IFN)-alpha/beta but not IFN-gamma signaling by inhibiting STAT1 and STAT2 phosphorylation.
  Journal
FEBS Lett 545:177-82 (2003)
DOI:10.1016/S0014-5793(03)00528-3
Reference
PMID:12805463
  Authors
Palosaari H, Parisien JP, Rodriguez JJ, Ulane CM, Horvath CM
  Title
STAT protein interference and suppression of cytokine signal transduction by measles virus V protein.
  Journal
J Virol 77:7635-44 (2003)
DOI:10.1128/JVI.77.13.7635-7644.2003
Reference
PMID:14585342
  Authors
Shaffer JA, Bellini WJ, Rota PA
  Title
The C protein of measles virus inhibits the type I interferon response.
  Journal
Virology 315:389-97 (2003)
DOI:10.1016/S0042-6822(03)00537-3
Reference
PMID:16971451
  Authors
Carsillo T, Traylor Z, Choi C, Niewiesk S, Oglesbee M
  Title
hsp72, a host determinant of measles virus neurovirulence.
  Journal
J Virol 80:11031-9 (2006)
DOI:10.1128/JVI.01438-06
Reference
PMID:15914229
  Authors
Zhang X, Bourhis JM, Longhi S, Carsillo T, Buccellato M, Morin B, Canard B, Oglesbee M
  Title
Hsp72 recognizes a P binding motif in the measles virus N protein C-terminus.
  Journal
Virology 337:162-74 (2005)
DOI:10.1016/j.virol.2005.03.035
Reference
PMID:29712906
  Authors
Ke Z, Strauss JD, Hampton CM, Brindley MA, Dillard RS, Leon F, Lamb KM, Plemper RK, Wright ER
  Title
Promotion of virus assembly and organization by the measles virus matrix protein.
  Journal
Nat Commun 9:1736 (2018)
DOI:10.1038/s41467-018-04058-2
Reference
PMID:24155404
  Authors
Pfaller CK, Radeke MJ, Cattaneo R, Samuel CE
  Title
Measles virus C protein impairs production of defective copyback double-stranded viral RNA and activation of protein kinase R.
  Journal
J Virol 88:456-68 (2014)
DOI:10.1128/JVI.02572-13
Reference
PMID:17686838
  Authors
Sato H, Masuda M, Kanai M, Tsukiyama-Kohara K, Yoneda M, Kai C
  Title
Measles virus N protein inhibits host translation by binding to eIF3-p40.
  Journal
J Virol 81:11569-76 (2007)
DOI:10.1128/JVI.00570-07
Reference
PMID:19895323
  Authors
Sion-Vardy N, Lasarov I, Delgado B, Gopas J, Benharroch D, Ariad S
  Title
Measles virus: evidence for association with lung cancer.
  Journal
Exp Lung Res 35:701-12 (2009)
DOI:10.3109/01902140902853176
Reference
PMID:16140759
  Authors
Chen M, Cortay JC, Logan IR, Sapountzi V, Robson CN, Gerlier D
  Title
Inhibition of ubiquitination and stabilization of human ubiquitin E3 ligase PIRH2 by measles virus phosphoprotein.
  Journal
J Virol 79:11824-36 (2005)
DOI:10.1128/JVI.79.18.11824-11836.2005
Reference
PMID:16699046
  Authors
Cruz CD, Palosaari H, Parisien JP, Devaux P, Cattaneo R, Ouchi T, Horvath CM
  Title
Measles virus V protein inhibits p53 family member p73.
  Journal
J Virol 80:5644-50 (2006)
DOI:10.1128/JVI.02400-05
Reference
PMID:10756053
  Authors
Servet-Delprat C, Vidalain PO, Azocar O, Le Deist F, Fischer A, Rabourdin-Combe C
  Title
Consequences of Fas-mediated human dendritic cell apoptosis induced by measles virus.
  Journal
J Virol 74:4387-93 (2000)
DOI:10.1128/JVI.74.9.4387-4393.2000
Reference
PMID:20601611
  Authors
Kushwah R, Hu J
  Title
Dendritic cell apoptosis: regulation of tolerance versus immunity.
  Journal
J Immunol 185:795-802 (2010)
DOI:10.4049/jimmunol.1000325
Reference
PMID:10590149
  Authors
Vidalain PO, Azocar O, Lamouille B, Astier A, Rabourdin-Combe C, Servet-Delprat C
  Title
Measles virus induces functional TRAIL production by human dendritic cells.
  Journal
J Virol 74:556-9 (2000)
DOI:10.1128/JVI.74.1.556-559.2000
Reference
PMID:11846228
  Authors
Vidalain PO, Azocar O, Rabourdin-Combe C, Servet-Delprat C
  Title
Measle virus-infected dendritic cells develop immunosuppressive and cytotoxic activities.
  Journal
Immunobiology 204:629-38 (2001)
DOI:10.1078/0171-2985-00102
Reference
PMID:10423127
  Authors
Engelking O, Fedorov LM, Lilischkis R, ter Meulen V, Schneider-Schaulies S
  Title
Measles virus-induced immunosuppression in vitro is associated with deregulation of G1 cell cycle control proteins.
  Journal
J Gen Virol 80 ( Pt 7):1599-608 (1999)
DOI:10.1099/0022-1317-80-7-1599
Reference
PMID:30510918
  Authors
Fan Y, Sanyal S, Bruzzone R
  Title
Breaking Bad: How Viruses Subvert the Cell Cycle.
  Journal
Front Cell Infect Microbiol 8:396 (2018)
DOI:10.3389/fcimb.2018.00396
Reference
PMID:20636817
  Authors
Griffin DE
  Title
Measles virus-induced suppression of immune responses.
  Journal
Immunol Rev 236:176-89 (2010)
DOI:10.1111/j.1600-065X.2010.00925.x
Reference
PMID:11385511
  Authors
Avota E, Avots A, Niewiesk S, Kane LP, Bommhardt U, ter Meulen V, Schneider-Schaulies S
  Title
Disruption of Akt kinase activation is important for immunosuppression induced by measles virus.
  Journal
Nat Med 7:725-31 (2001)
DOI:10.1038/89106
Reference
PMID:15308747
  Authors
Avota E, Muller N, Klett M, Schneider-Schaulies S
  Title
Measles virus interacts with and alters signal transduction in T-cell lipid rafts.
  Journal
J Virol 78:9552-9 (2004)
DOI:10.1128/JVI.78.17.9552-9559.2004
Reference
PMID:16963735
  Authors
Yanagi Y, Takeda M, Ohno S
  Title
Measles virus: cellular receptors, tropism and pathogenesis.
  Journal
J Gen Virol 87:2767-79 (2006)
DOI:10.1099/vir.0.82221-0
Reference
PMID:16237742
  Authors
Kerdiles YM, Sellin CI, Druelle J, Horvat B
  Title
Immunosuppression caused by measles virus: role of viral proteins.
  Journal
Rev Med Virol 16:49-63 (2006)
DOI:10.1002/rmv.486
Related
pathway
pteh04110  Cell cycle
pteh04115  p53 signaling pathway
pteh04120  Ubiquitin mediated proteolysis
pteh04210  Apoptosis
pteh04620  Toll-like receptor signaling pathway
pteh04622  RIG-I-like receptor signaling pathway
pteh04630  JAK-STAT signaling pathway
pteh04658  Th1 and Th2 cell differentiation
pteh04660  T cell receptor signaling pathway
KO pathway
ko05162   
LinkDB

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