KEGG   PATHWAY: tng04010
Entry
tng04010                    Pathway                                
Name
MAPK signaling pathway - Tetraodon nigroviridis (spotted green pufferfish)
Description
The mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in various cellular functions, including cell proliferation, differentiation and migration. Mammals express at least four distinctly regulated groups of MAPKs, extracellular signal-related kinases (ERK)-1/2, Jun amino-terminal kinases (JNK1/2/3), p38 proteins (p38alpha/beta/gamma/delta) and ERK5, that are activated by specific MAPKKs: MEK1/2 for ERK1/2, MKK3/6 for the p38, MKK4/7 (JNKK1/2) for the JNKs, and MEK5 for ERK5. Each MAPKK, however, can be activated by more than one MAPKKK, increasing the complexity and diversity of MAPK signalling. Presumably each MAPKKK confers responsiveness to distinct stimuli. For example, activation of ERK1/2 by growth factors depends on the MAPKKK c-Raf, but other MAPKKKs may activate ERK1/2 in response to pro-inflammatory stimuli.
Class
Environmental Information Processing; Signal transduction
Pathway map
tng04010  MAPK signaling pathway
tng04010

Other DBs
GO: 0000165
Organism
Tetraodon nigroviridis (spotted green pufferfish) [GN:tng]
Gene
GSTEN00023728G001  unnamed protein product [KO:K04344]
GSTEN00021312G001  unnamed protein product [KO:K04344]
GSTEN00009266G001  unnamed protein product [KO:K04849]
GSTEN00022583G001  unnamed protein product [KO:K04851]
GSTEN00027380G001  unnamed protein product [KO:K04851]
GSTEN00016193G001  unnamed protein product [KO:K04852]
GSTEN00028843G001  unnamed protein product [KO:K04852]
GSTEN00026488G001  unnamed protein product [KO:K04853]
GSTEN00023513G001  unnamed protein product [KO:K04853]
GSTEN00013197G001  unnamed protein product [KO:K04854]
GSTEN00021853G001  unnamed protein product [KO:K04855]
GSTEN00034807G001  unnamed protein product [KO:K04856]
GSTEN00023741G001  unnamed protein product [KO:K04856]
GSTEN00028107G001  unnamed protein product [KO:K04857]
GSTEN00015785G001  unnamed protein product [KO:K04857]
GSTEN00035534G001  unnamed protein product [KO:K04858]
GSTEN00020826G001  unnamed protein product [KO:K04858]
GSTEN00027409G001  unnamed protein product [KO:K04859]
GSTEN00027514G001  unnamed protein product [KO:K04859]
GSTEN00027968G001  unnamed protein product [KO:K04860]
GSTEN00027377G001  unnamed protein product [KO:K04860]
GSTEN00007786G001  unnamed protein product [KO:K04861]
GSTEN00014505G001  unnamed protein product [KO:K04861]
GSTEN00004325G001  unnamed protein product [KO:K04862]
GSTEN00031767G001  unnamed protein product [KO:K04863]
GSTEN00028127G001  unnamed protein product [KO:K04864]
GSTEN00029194G001  unnamed protein product [KO:K04865]
GSTEN00027037G001  unnamed protein product [KO:K04865]
GSTEN00001995G001  unnamed protein product [KO:K04866]
GSTEN00022457G001  unnamed protein product [KO:K04866]
GSTEN00038173G001  unnamed protein product [KO:K04866]
GSTEN00034821G001  unnamed protein product [KO:K04867]
GSTEN00021237G001  unnamed protein product [KO:K04867]
GSTEN00021868G001  unnamed protein product [KO:K04868]
GSTEN00022459G001  unnamed protein product [KO:K04869]
GSTEN00026371G001  unnamed protein product [KO:K04870]
GSTEN00015423G001  unnamed protein product [KO:K04871]
GSTEN00033733G001  unnamed protein product [KO:K04871]
GSTEN00015421G001  unnamed protein product [KO:K04872]
GSTEN00033735G001  unnamed protein product [KO:K04872]
GSTEN00015422G001  unnamed protein product [KO:K04873]
GSTEN00033734G001  unnamed protein product [KO:K04873]
GSTEN00019760G001  unnamed protein product [KO:K04345] [EC:2.7.11.11]
GSTEN00026232G001  unnamed protein product [KO:K04345] [EC:2.7.11.11]
GSTEN00022860G001  unnamed protein product [KO:K04345] [EC:2.7.11.11]
GSTEN00016205G001  unnamed protein product [KO:K04345] [EC:2.7.11.11]
GSTEN00009847G001  unnamed protein product [KO:K19662] [EC:2.7.11.13]
GSTEN00021867G001  unnamed protein product [KO:K19662] [EC:2.7.11.13]
GSTEN00015420G001  unnamed protein product [KO:K19663] [EC:2.7.11.13]
GSTEN00015763G001  unnamed protein product [KO:K04346]
GSTEN00013392G001  unnamed protein product [KO:K04347]
GSTEN00009662G001  unnamed protein product [KO:K04348] [EC:3.1.3.16]
GSTEN00019008G001  unnamed protein product [KO:K04348] [EC:3.1.3.16]
GSTEN00034888G001  unnamed protein product [KO:K04348] [EC:3.1.3.16]
GSTEN00013810G001  unnamed protein product [KO:K04348] [EC:3.1.3.16]
GSTEN00010354G001  unnamed protein product [KO:K04348] [EC:3.1.3.16]
GSTEN00018677G001  unnamed protein product [KO:K06268]
GSTEN00007813G001  unnamed protein product [KO:K06268]
GSTEN00021454G001  unnamed protein product [KO:K04349]
GSTEN00035642G001  unnamed protein product [KO:K04349]
GSTEN00025307G001  unnamed protein product [KO:K12326]
GSTEN00028605G001  unnamed protein product [KO:K12326]
GSTEN00028606G001  unnamed protein product [KO:K12326]
GSTEN00035197G001  unnamed protein product [KO:K04350]
GSTEN00032355G001  unnamed protein product [KO:K04350]
GSTEN00001427G001  unnamed protein product [KO:K12361]
GSTEN00024432G001  unnamed protein product [KO:K08018]
GSTEN00028720G001  unnamed protein product [KO:K04352]
GSTEN00013536G001  unnamed protein product [KO:K04353]
GSTEN00023474G001  unnamed protein product [KO:K04353]
GSTEN00012332G001  unnamed protein product [KO:K07836]
GSTEN00024402G001  unnamed protein product [KO:K04357]
GSTEN00027441G001  unnamed protein product [KO:K08774]
GSTEN00017026G001  unnamed protein product [KO:K18496]
GSTEN00033767G001  unnamed protein product [KO:K18496]
GSTEN00024480G001  unnamed protein product [KO:K18497]
GSTEN00030976G001  unnamed protein product [KO:K04358]
GSTEN00005561G001  unnamed protein product [KO:K04358]
GSTEN00005197G001  unnamed protein product [KO:K04358]
GSTEN00021543G001  unnamed protein product [KO:K04358]
GSTEN00012081G001  unnamed protein product [KO:K04358]
GSTEN00005377G001  unnamed protein product [KO:K04358]
GSTEN00020123G001  unnamed protein product [KO:K04358]
GSTEN00016775G001  unnamed protein product [KO:K04358]
GSTEN00017034G001  unnamed protein product [KO:K04358]
GSTEN00019182G001  unnamed protein product [KO:K04358]
GSTEN00024466G001  unnamed protein product [KO:K04358]
GSTEN00029595G001  unnamed protein product [KO:K04358]
GSTEN00035824G001  unnamed protein product [KO:K04358]
GSTEN00026526G001  unnamed protein product [KO:K04358]
GSTEN00017348G001  unnamed protein product [KO:K04358]
GSTEN00021542G001  unnamed protein product [KO:K22428]
GSTEN00016774G001  unnamed protein product [KO:K22428]
GSTEN00033889G001  unnamed protein product [KO:K02582]
GSTEN00027982G001  unnamed protein product [KO:K02582]
GSTEN00007157G001  unnamed protein product [KO:K04355]
GSTEN00014675G001  unnamed protein product [KO:K04526]
GSTEN00008749G001  unnamed protein product [KO:K04526]
GSTEN00023793G001  unnamed protein product [KO:K05459]
GSTEN00019790G001  unnamed protein product [KO:K13769]
GSTEN00034853G001  unnamed protein product [KO:K04359]
GSTEN00033366G001  unnamed protein product [KO:K04359]
GSTEN00034840G001  unnamed protein product [KO:K17386]
GSTEN00024421G001  unnamed protein product [KO:K05450]
GSTEN00009365G001  unnamed protein product [KO:K05450]
GSTEN00025637G001  unnamed protein product [KO:K05461]
GSTEN00012177G001  unnamed protein product [KO:K05448]
GSTEN00017362G001  unnamed protein product [KO:K05448]
GSTEN00020306G001  unnamed protein product [KO:K16859]
GSTEN00006242G001  unnamed protein product [KO:K05449]
GSTEN00035532G001  unnamed protein product [KO:K05460]
GSTEN00020823G001  unnamed protein product [KO:K05460]
GSTEN00032925G001  unnamed protein product [KO:K05465]
GSTEN00017520G001  unnamed protein product [KO:K05466]
GSTEN00030667G001  unnamed protein product [KO:K05466]
GSTEN00032578G001  unnamed protein product [KO:K05462]
GSTEN00032580G001  unnamed protein product [KO:K05462]
GSTEN00035674G001  unnamed protein product [KO:K05462]
GSTEN00033951G001  unnamed protein product [KO:K05462]
GSTEN00030897G001  unnamed protein product [KO:K05462]
GSTEN00008283G001  unnamed protein product [KO:K05462]
GSTEN00017238G001  unnamed protein product [KO:K05452]
GSTEN00029381G001  unnamed protein product [KO:K05452]
GSTEN00027733G001  unnamed protein product [KO:K25414]
GSTEN00025328G001  unnamed protein product [KO:K04361] [EC:2.7.10.1]
GSTEN00025331G001  unnamed protein product [KO:K04361] [EC:2.7.10.1]
GSTEN00027642G001  unnamed protein product [KO:K04361] [EC:2.7.10.1]
GSTEN00035042G001  unnamed protein product [KO:K05083] [EC:2.7.10.1]
GSTEN00028067G001  unnamed protein product [KO:K05084] [EC:2.7.10.1]
GSTEN00027265G001  unnamed protein product [KO:K05084] [EC:2.7.10.1]
GSTEN00030469G001  unnamed protein product [KO:K05085] [EC:2.7.10.1]
GSTEN00015851G001  unnamed protein product [KO:K05085] [EC:2.7.10.1]
GSTEN00034863G001  unnamed protein product [KO:K04362] [EC:2.7.10.1]
GSTEN00025402G001  unnamed protein product [KO:K04362] [EC:2.7.10.1]
GSTEN00025098G001  unnamed protein product [KO:K05093] [EC:2.7.10.1]
GSTEN00023332G001  unnamed protein product [KO:K05094] [EC:2.7.10.1]
GSTEN00014622G001  unnamed protein product [KO:K05095] [EC:2.7.10.1]
GSTEN00035027G001  unnamed protein product [KO:K02583]
GSTEN00034081G001  unnamed protein product [KO:K02583]
GSTEN00019520G001  unnamed protein product [KO:K03176] [EC:2.7.10.1]
GSTEN00029370G001  unnamed protein product [KO:K04360] [EC:2.7.10.1]
GSTEN00014464G001  unnamed protein product [KO:K04360] [EC:2.7.10.1]
GSTEN00027765G001  unnamed protein product [KO:K04527] [EC:2.7.10.1]
GSTEN00028880G001  unnamed protein product [KO:K04527] [EC:2.7.10.1]
GSTEN00035595G001  unnamed protein product [KO:K05087] [EC:2.7.10.1]
GSTEN00022424G001  unnamed protein product [KO:K05087] [EC:2.7.10.1]
GSTEN00032764G001  unnamed protein product [KO:K04363] [EC:2.7.10.1]
GSTEN00026578G001  unnamed protein product [KO:K05089] [EC:2.7.10.1]
GSTEN00014570G001  unnamed protein product [KO:K05089] [EC:2.7.10.1]
GSTEN00014572G001  unnamed protein product [KO:K05090] [EC:2.7.10.1]
GSTEN00026580G001  unnamed protein product [KO:K05090] [EC:2.7.10.1]
GSTEN00006766G001  unnamed protein product [KO:K05091] [EC:2.7.10.1]
GSTEN00032762G001  unnamed protein product [KO:K05091] [EC:2.7.10.1]
GSTEN00023864G001  unnamed protein product [KO:K05096] [EC:2.7.10.1]
GSTEN00031226G001  unnamed protein product [KO:K05096] [EC:2.7.10.1]
GSTEN00017100G001  unnamed protein product [KO:K05097] [EC:2.7.10.1]
GSTEN00032761G001  unnamed protein product [KO:K05098] [EC:2.7.10.1]
GSTEN00029819G001  unnamed protein product [KO:K05099] [EC:2.7.10.1]
GSTEN00020611G001  unnamed protein product [KO:K05103] [EC:2.7.10.1]
GSTEN00027500G001  unnamed protein product [KO:K05103] [EC:2.7.10.1]
GSTEN00024538G001  unnamed protein product [KO:K05126] [EC:2.7.10.1]
GSTEN00006471G001  unnamed protein product [KO:K04364]
GSTEN00018287G001  unnamed protein product [KO:K03099]
GSTEN00035791G001  unnamed protein product [KO:K03099]
GSTEN00008944G001  unnamed protein product [KO:K03099]
GSTEN00003165G001  unnamed protein product [KO:K02833]
GSTEN00021499G001  unnamed protein product [KO:K02833]
GSTEN00022812G001  unnamed protein product [KO:K07827]
GSTEN00017804G001  unnamed protein product [KO:K07830]
GSTEN00014485G001  unnamed protein product [KO:K07831]
GSTEN00020048G001  unnamed protein product [KO:K08845] [EC:2.7.11.1]
GSTEN00013902G001  unnamed protein product [KO:K04365] [EC:2.7.11.1]
GSTEN00023725G001  unnamed protein product [KO:K04366] [EC:2.7.11.1]
GSTEN00016020G001  unnamed protein product [KO:K04368] [EC:2.7.12.2]
GSTEN00004843G001  unnamed protein product [KO:K04369] [EC:2.7.12.2]
GSTEN00013453G001  unnamed protein product [KO:K04370]
GSTEN00028566G001  unnamed protein product [KO:K04371] [EC:2.7.11.24]
GSTEN00021811G001  unnamed protein product [KO:K04371] [EC:2.7.11.24]
GSTEN00019259G001  unnamed protein product [KO:K04372] [EC:2.7.11.1]
GSTEN00012634G001  unnamed protein product [KO:K04372] [EC:2.7.11.1]
GSTEN00032087G001  unnamed protein product [KO:K04373] [EC:2.7.11.1]
GSTEN00029331G001  unnamed protein product [KO:K04373] [EC:2.7.11.1]
GSTEN00025809G001  unnamed protein product [KO:K04373] [EC:2.7.11.1]
GSTEN00021675G001  unnamed protein product [KO:K04374]
GSTEN00003483G001  unnamed protein product [KO:K04375]
GSTEN00014173G001  unnamed protein product [KO:K04376]
GSTEN00031807G001  unnamed protein product [KO:K04377]
GSTEN00004148G001  unnamed protein product [KO:K04378]
GSTEN00025109G001  unnamed protein product [KO:K04378]
GSTEN00030333G001  unnamed protein product [KO:K04379]
GSTEN00022291G001  unnamed protein product [KO:K04380]
GSTEN00018347G001  unnamed protein product [KO:K04381]
GSTEN00006129G001  unnamed protein product [KO:K04381]
GSTEN00023831G001  unnamed protein product [KO:K04381]
GSTEN00033633G001  unnamed protein product [KO:K16342] [EC:3.1.1.4]
GSTEN00035186G001  unnamed protein product [KO:K13375]
GSTEN00011872G001  unnamed protein product [KO:K13376]
GSTEN00031190G001  unnamed protein product [KO:K13376]
GSTEN00032323G001  unnamed protein product [KO:K13377]
GSTEN00030322G001  unnamed protein product [KO:K13377]
GSTEN00015334G001  unnamed protein product [KO:K03158]
GSTEN00021168G001  unnamed protein product [KO:K04723]
GSTEN00000177G001  unnamed protein product [KO:K04674] [EC:2.7.11.30]
GSTEN00000178G001  unnamed protein product [KO:K04674] [EC:2.7.11.30]
GSTEN00035077G001  unnamed protein product [KO:K04674] [EC:2.7.11.30]
GSTEN00012314G001  unnamed protein product [KO:K04388] [EC:2.7.11.30]
GSTEN00025846G001  unnamed protein product [KO:K04388] [EC:2.7.11.30]
GSTEN00035878G001  unnamed protein product [KO:K04388] [EC:2.7.11.30]
GSTEN00009736G001  unnamed protein product [KO:K04392]
GSTEN00024153G001  unnamed protein product [KO:K04392]
GSTEN00034813G001  unnamed protein product [KO:K07860]
GSTEN00023599G001  unnamed protein product [KO:K04393]
GSTEN00004992G001  unnamed protein product [KO:K04393]
GSTEN00014160G001  unnamed protein product [KO:K04393]
GSTEN00017689G001  unnamed protein product [KO:K03171]
GSTEN00013715G001  unnamed protein product [KO:K02187] [EC:3.4.22.56]
GSTEN00025207G001  unnamed protein product [KO:K03173] [EC:2.3.2.27]
GSTEN00020052G001  unnamed protein product [KO:K03173] [EC:2.3.2.27]
GSTEN00017168G001  unnamed protein product [KO:K03173] [EC:2.3.2.27]
GSTEN00033726G001  unnamed protein product [KO:K02308]
GSTEN00009038G001  unnamed protein product [KO:K04730] [EC:2.7.11.1]
GSTEN00029683G001  unnamed protein product [KO:K04733] [EC:2.7.11.1]
GSTEN00018197G001  unnamed protein product [KO:K03175] [EC:2.3.2.27]
GSTEN00013393G001  unnamed protein product [KO:K04402]
GSTEN00030892G001  unnamed protein product [KO:K04402]
GSTEN00004743G001  unnamed protein product [KO:K04402]
GSTEN00004790G001  unnamed protein product [KO:K04402]
GSTEN00031910G001  unnamed protein product [KO:K04402]
GSTEN00034825G001  unnamed protein product [KO:K04403]
GSTEN00003790G001  unnamed protein product [KO:K04404]
GSTEN00007940G001  unnamed protein product [KO:K04405]
GSTEN00029186G001  unnamed protein product [KO:K04407] [EC:2.7.11.1]
GSTEN00005875G001  unnamed protein product [KO:K04409] [EC:2.7.11.1]
GSTEN00035962G001  unnamed protein product [KO:K04410] [EC:2.7.11.1]
GSTEN00032714G001  unnamed protein product [KO:K04410] [EC:2.7.11.1]
GSTEN00013203G001  unnamed protein product [KO:K04410] [EC:2.7.11.1]
GSTEN00009280G001  unnamed protein product [KO:K04411]
GSTEN00017365G001  unnamed protein product [KO:K04412]
GSTEN00008453G001  unnamed protein product [KO:K04414] [EC:2.7.11.1]
GSTEN00016563G001  unnamed protein product [KO:K04415] [EC:2.7.11.25]
GSTEN00006262G001  unnamed protein product [KO:K04419] [EC:2.7.11.25]
GSTEN00003091G001  unnamed protein product [KO:K04420] [EC:2.7.11.25]
GSTEN00031843G001  unnamed protein product [KO:K04420] [EC:2.7.11.25]
GSTEN00023918G001  unnamed protein product [KO:K04421] [EC:2.7.11.25]
GSTEN00027814G001  unnamed protein product [KO:K04421] [EC:2.7.11.25]
GSTEN00035806G001  unnamed protein product [KO:K04417] [EC:2.7.11.25]
GSTEN00014792G001  unnamed protein product [KO:K04418] [EC:2.7.11.25]
GSTEN00031546G001  unnamed protein product [KO:K17534] [EC:2.7.11.25]
GSTEN00023658G001  unnamed protein product [KO:K04423] [EC:2.7.11.25]
GSTEN00027624G001  unnamed protein product [KO:K04423] [EC:2.7.11.25]
GSTEN00030516G001  unnamed protein product [KO:K04422] [EC:2.7.11.25]
GSTEN00031439G001  unnamed protein product [KO:K04424] [EC:2.7.11.25]
GSTEN00020952G001  unnamed protein product [KO:K04424] [EC:2.7.11.25]
GSTEN00010129G001  unnamed protein product [KO:K04427] [EC:2.7.11.25]
GSTEN00030726G001  unnamed protein product [KO:K04428] [EC:2.7.11.25]
GSTEN00007195G001  unnamed protein product [KO:K04429] [EC:2.7.11.1]
GSTEN00030054G001  unnamed protein product [KO:K04429] [EC:2.7.11.1]
GSTEN00017262G001  unnamed protein product [KO:K04429] [EC:2.7.11.1]
GSTEN00021736G001  unnamed protein product [KO:K04430] [EC:2.7.12.2]
GSTEN00021246G001  unnamed protein product [KO:K04430] [EC:2.7.12.2]
GSTEN00026353G001  unnamed protein product [KO:K04431] [EC:2.7.12.2]
GSTEN00018597G001  unnamed protein product [KO:K04433] [EC:2.7.12.2]
GSTEN00018222G001  unnamed protein product [KO:K04434]
GSTEN00008510G001  unnamed protein product [KO:K04434]
GSTEN00033315G001  unnamed protein product [KO:K04435]
GSTEN00033316G001  unnamed protein product [KO:K04435]
GSTEN00021804G001  unnamed protein product [KO:K04436]
GSTEN00008691G001  unnamed protein product [KO:K04437]
GSTEN00002679G001  unnamed protein product [KO:K04438]
GSTEN00002027G001  unnamed protein product [KO:K04438]
GSTEN00026698G001  unnamed protein product [KO:K04438]
GSTEN00011655G001  unnamed protein product [KO:K04438]
GSTEN00021161G001  unnamed protein product [KO:K04439]
GSTEN00006671G001  unnamed protein product [KO:K04439]
GSTEN00014682G001  unnamed protein product [KO:K04439]
GSTEN00019882G001  unnamed protein product [KO:K04440] [EC:2.7.11.24]
GSTEN00014434G001  unnamed protein product [KO:K04440] [EC:2.7.11.24]
GSTEN00030625G001  unnamed protein product [KO:K04440] [EC:2.7.11.24]
GSTEN00001777G001  unnamed protein product [KO:K04441] [EC:2.7.11.24]
GSTEN00015915G001  unnamed protein product [KO:K04441] [EC:2.7.11.24]
GSTEN00028159G001  unnamed protein product [KO:K04441] [EC:2.7.11.24]
GSTEN00020585G001  unnamed protein product [KO:K04441] [EC:2.7.11.24]
GSTEN00006610G001  unnamed protein product [KO:K04441] [EC:2.7.11.24]
GSTEN00013269G001  unnamed protein product [KO:K04441] [EC:2.7.11.24]
GSTEN00013270G001  unnamed protein product [KO:K04441] [EC:2.7.11.24]
GSTEN00030940G001  unnamed protein product [KO:K04442] [EC:2.7.11.1]
GSTEN00014009G001  unnamed protein product [KO:K04443] [EC:2.7.11.1]
GSTEN00027280G001  unnamed protein product [KO:K04444] [EC:2.7.11.1]
GSTEN00013642G001  unnamed protein product [KO:K04444] [EC:2.7.11.1]
GSTEN00035718G001  unnamed protein product [KO:K04445] [EC:2.7.11.1]
GSTEN00030003G001  unnamed protein product [KO:K16510] [EC:2.7.11.1]
GSTEN00004162G001  unnamed protein product [KO:K04446]
GSTEN00021435G001  unnamed protein product [KO:K17333]
GSTEN00020512G001  unnamed protein product [KO:K04448]
GSTEN00015028G001  unnamed protein product [KO:K04448]
GSTEN00013845G001  unnamed protein product [KO:K04448]
GSTEN00019308G001  unnamed protein product [KO:K04449]
GSTEN00019217G001  unnamed protein product [KO:K04451]
GSTEN00013575G001  unnamed protein product [KO:K04452]
GSTEN00030422G001  unnamed protein product [KO:K04453]
GSTEN00025373G001  unnamed protein product [KO:K04454]
GSTEN00028730G001  unnamed protein product [KO:K04454]
GSTEN00016260G001  unnamed protein product [KO:K04455]
GSTEN00029064G001  unnamed protein product [KO:K04455]
GSTEN00003798G001  unnamed protein product [KO:K04456] [EC:2.7.11.1]
GSTEN00016324G001  unnamed protein product [KO:K04456] [EC:2.7.11.1]
GSTEN00009507G001  unnamed protein product [KO:K04456] [EC:2.7.11.1]
GSTEN00007800G001  unnamed protein product [KO:K04456] [EC:2.7.11.1]
GSTEN00022201G001  unnamed protein product [KO:K04457] [EC:3.1.3.16]
GSTEN00032227G001  unnamed protein product [KO:K04457] [EC:3.1.3.16]
GSTEN00014819G001  unnamed protein product [KO:K04457] [EC:3.1.3.16]
GSTEN00003441G001  unnamed protein product [KO:K04458] [EC:3.1.3.48]
GSTEN00038501G001  unnamed protein product [KO:K18018] [EC:3.1.3.48]
GSTEN00017097G001  unnamed protein product [KO:K21278] [EC:3.1.3.16 3.1.3.48]
GSTEN00028595G001  unnamed protein product [KO:K04459] [EC:3.1.3.16 3.1.3.48]
GSTEN00024767G001  unnamed protein product [KO:K04459] [EC:3.1.3.16 3.1.3.48]
GSTEN00020021G001  unnamed protein product [KO:K04459] [EC:3.1.3.16 3.1.3.48]
GSTEN00005061G001  unnamed protein product [KO:K04459] [EC:3.1.3.16 3.1.3.48]
GSTEN00012867G001  unnamed protein product [KO:K04459] [EC:3.1.3.16 3.1.3.48]
GSTEN00027610G001  unnamed protein product [KO:K04459] [EC:3.1.3.16 3.1.3.48]
GSTEN00023717G001  unnamed protein product [KO:K04459] [EC:3.1.3.16 3.1.3.48]
GSTEN00029811G001  unnamed protein product [KO:K21946] [EC:3.1.3.16 3.1.3.48]
GSTEN00030399G001  unnamed protein product [KO:K20216] [EC:3.1.3.16 3.1.3.48]
GSTEN00026928G001  unnamed protein product [KO:K17614] [EC:3.1.3.16 3.1.3.48]
GSTEN00021067G001  unnamed protein product [KO:K17614] [EC:3.1.3.16 3.1.3.48]
GSTEN00011148G001  unnamed protein product [KO:K17614] [EC:3.1.3.16 3.1.3.48]
GSTEN00014338G001  unnamed protein product [KO:K04461] [EC:3.1.3.16]
GSTEN00009552G001  unnamed protein product [KO:K04461] [EC:3.1.3.16]
GSTEN00016340G001  unnamed protein product [KO:K03283]
GSTEN00034205G001  unnamed protein product [KO:K03283]
GSTEN00007190G001  unnamed protein product [KO:K03283]
GSTEN00007191G001  unnamed protein product [KO:K03283]
GSTEN00007193G001  unnamed protein product [KO:K03283]
GSTEN00028179G001  unnamed protein product [KO:K03283]
GSTEN00018103G001  unnamed protein product [KO:K04463] [EC:2.7.12.2]
GSTEN00028301G001  unnamed protein product [KO:K04464] [EC:2.7.11.24]
GSTEN00013617G001  unnamed protein product [KO:K04465]
GSTEN00023538G001  unnamed protein product [KO:K04465]
GSTEN00022300G001  unnamed protein product [KO:K04466] [EC:2.7.11.25]
GSTEN00021996G001  unnamed protein product [KO:K04466] [EC:2.7.11.25]
GSTEN00022283G001  unnamed protein product [KO:K04467] [EC:2.7.11.10]
GSTEN00030651G001  unnamed protein product [KO:K04467] [EC:2.7.11.10]
GSTEN00029571G001  unnamed protein product [KO:K07209] [EC:2.7.11.10]
GSTEN00004906G001  unnamed protein product [KO:K07210]
GSTEN00006817G001  unnamed protein product [KO:K04468] [EC:2.7.11.24]
GSTEN00004800G001  unnamed protein product [KO:K04468] [EC:2.7.11.24]
GSTEN00003769G001  unnamed protein product [KO:K02580]
GSTEN00003770G001  unnamed protein product [KO:K02580]
GSTEN00024998G001  unnamed protein product [KO:K04469]
GSTEN00001997G001  unnamed protein product [KO:K04735]
GSTEN00000890G001  unnamed protein product [KO:K04735]
GSTEN00005456G001  unnamed protein product [KO:K04735]
GSTEN00014803G001  unnamed protein product [KO:K09253]
Compound
C00076  Calcium cation
C00165  Diacylglycerol
C00338  Lipopolysaccharide
C00575  3',5'-Cyclic AMP
C01245  D-myo-Inositol 1,4,5-trisphosphate
Reference
PMID:11749383
  Authors
Chen Z, Gibson TB, Robinson F, Silvestro L, Pearson G, Xu B, Wright A, Vanderbilt C, Cobb MH.
  Title
MAP kinases.
  Journal
Chem Rev 101:2449-76 (2001)
DOI:10.1021/cr000241p
Reference
PMID:12191611
  Authors
Tanoue T, Nishida E.
  Title
Docking interactions in the mitogen-activated protein kinase cascades.
  Journal
Pharmacol Ther 93:193-202 (2002)
DOI:10.1016/S0163-7258(02)00188-2
Reference
PMID:12947395
  Authors
Dent P, Yacoub A, Fisher PB, Hagan MP, Grant S.
  Title
MAPK pathways in radiation responses.
  Journal
Oncogene 22:5885-96 (2003)
DOI:10.1038/sj.onc.1206701
Reference
PMID:12676795
  Authors
Huang EJ, Reichardt LF.
  Title
Trk receptors: roles in neuronal signal transduction.
  Journal
Annu Rev Biochem 72:609-42 (2003)
DOI:10.1146/annurev.biochem.72.121801.161629
Reference
PMID:11369511
  Authors
Harper SJ, LoGrasso P.
  Title
Signalling for survival and death in neurones: the role of stress-activated kinases, JNK and p38.
  Journal
Cell Signal 13:299-310 (2001)
DOI:10.1016/S0898-6568(01)00148-6
Reference
PMID:12390245
  Authors
Takeda K, Ichijo H
  Title
Neuronal p38 MAPK signalling: an emerging regulator of cell fate and function in the nervous system.
  Journal
Genes Cells 7:1099-111 (2002)
DOI:10.1046/j.1365-2443.2002.00591.x
Reference
PMID:14597384
  Authors
Yang SH, Sharrocks AD, Whitmarsh AJ.
  Title
Transcriptional regulation by the MAP kinase signaling cascades.
  Journal
Gene 320:3-21 (2003)
DOI:10.1016/S0378-1119(03)00816-3
Reference
PMID:12566928
  Authors
Zhu X, Lee HG, Raina AK, Perry G, Smith MA.
  Title
The role of mitogen-activated protein kinase pathways in Alzheimer's disease.
  Journal
Neurosignals 11:270-81 (2002)
DOI:10.1159/000067426
Reference
PMID:12849693
  Authors
Cho H, Lee J, Kwak NJ, Lee KH, Rha S, Kim YH, Cho YY, Yang KH, Kim K, Lim Y.
  Title
Silica induces nuclear factor-kappaB activation through TAK1 and NIK in Rat2 cell line.
  Journal
Toxicol Lett 143:323-30 (2003)
DOI:10.1016/S0378-4274(03)00193-0
Reference
PMID:20602996
  Authors
Lemmon MA, Schlessinger J
  Title
Cell signaling by receptor tyrosine kinases.
  Journal
Cell 141:1117-34 (2010)
DOI:10.1016/j.cell.2010.06.011
Reference
PMID:22367796
  Authors
Skaper SD
  Title
The neurotrophin family of neurotrophic factors: an overview.
  Journal
Methods Mol Biol 846:1-12 (2012)
DOI:10.1007/978-1-61779-536-7_1
Reference
PMID:23085193
  Authors
Chu WM
  Title
Tumor necrosis factor.
  Journal
Cancer Lett 328:222-5 (2013)
DOI:10.1016/j.canlet.2012.10.014
Reference
PMID:22296764
  Authors
Newton K, Dixit VM
  Title
Signaling in innate immunity and inflammation.
  Journal
Cold Spring Harb Perspect Biol 4:a006049 (2012)
DOI:10.1101/cshperspect.a006049
Reference
PMID:19483709
  Authors
Gaestel M, Kotlyarov A, Kracht M
  Title
Targeting innate immunity protein kinase signalling in inflammation.
  Journal
Nat Rev Drug Discov 8:480-99 (2009)
DOI:10.1038/nrd2829
Reference
PMID:23664135
  Authors
Ajibade AA, Wang HY, Wang RF
  Title
Cell type-specific function of TAK1 in innate immune signaling.
  Journal
Trends Immunol 34:307-16 (2013)
DOI:10.1016/j.it.2013.03.007
Reference
PMID:24892271
  Authors
Turner MD, Nedjai B, Hurst T, Pennington DJ
  Title
Cytokines and chemokines: At the crossroads of cell signalling and inflammatory disease.
  Journal
Biochim Biophys Acta 1843:2563-2582 (2014)
DOI:10.1016/j.bbamcr.2014.05.014
Related
pathway
tng04070  Phosphatidylinositol signaling system
tng04110  Cell cycle
tng04115  p53 signaling pathway
tng04210  Apoptosis
tng04310  Wnt signaling pathway
KO pathway
ko04010   
LinkDB

DBGET integrated database retrieval system