KEGG   PATHWAY: rno04060
Entry
rno04060                    Pathway                                
Name
Cytokine-cytokine receptor interaction - Rattus norvegicus (rat)
Description
Cytokines are soluble extracellular proteins or glycoproteins that are crucial intercellular regulators and mobilizers of cells engaged in innate as well as adaptive inflammatory host defenses, cell growth, differentiation, cell death, angiogenesis, and development and repair processes aimed at the restoration of homeostasis. Cytokines are released by various cells in the body, usually in response to an activating stimulus, and they induce responses through binding to specific receptors on the cell surface of target cells. Cytokines can be grouped by structure into different families and their receptors can likewise be grouped.
Class
Environmental Information Processing; Signaling molecules and interaction
Pathway map
rno04060  Cytokine-cytokine receptor interaction
rno04060

Organism
Rattus norvegicus (rat) [GN:rno]
Gene
100124593  Cxcr6; C-X-C chemokine receptor type 6 [KO:K04191]
100911249  Ifnl1; interferon lambda-2 [KO:K22669]
100911527  Ifna4l1; interferon alpha-11-like [KO:K05414]
100912314  [KO:K05414]
100912356  [KO:K05414]
103693341  Tnfrsf13b; tumor necrosis factor receptor superfamily member 13B [KO:K05150]
114103  Il5ra; interleukin-5 receptor subunit alpha precursor [KO:K05067]
114105  Cxcl2; C-X-C motif chemokine 2 precursor [KO:K05505]
114492  Ccl28; C-C motif chemokine 28 precursor [KO:K05513]
116465  Ifngr1; interferon gamma receptor 1 precursor [KO:K05132]
116472  Il17b; interleukin-17B precursor [KO:K05490]
116553  Il13; interleukin-13 precursor [KO:K05435]
116558  Il9; interleukin-9 precursor [KO:K05432]
116562  Il2; interleukin-2 precursor [KO:K05429]
116630  Csf2; granulocyte-macrophage colony-stimulating factor precursor [KO:K05427]
116637  Ccl4; C-C motif chemokine 4 precursor [KO:K12964]
116996  Il16; pro-interleukin-16 [KO:K22628]
117022  Il1r2; interleukin-1 receptor type 2 precursor [KO:K04387]
117027  Ccr3; C-C chemokine receptor type 3 [KO:K04178]
117029  Ccr5; C-C chemokine receptor type 5 [KO:K04180]
117516  Tnfsf11; tumor necrosis factor ligand superfamily member 11 [KO:K05473]
117518  Ccl17; C-C motif chemokine 17 precursor [KO:K21083]
117539  Il10ra; interleukin-10 receptor subunit alpha precursor [KO:K05134]
117551  Ccl22; C-C motif chemokine 22 precursor [KO:K21095]
134487075  [KO:K05414]
134487077  [KO:K05414]
140590  Bmpr2; bone morphogenetic protein receptor type-2 precursor [KO:K04671] [EC:2.7.11.30]
140924  Il2rg; cytokine receptor common subunit gamma precursor [KO:K05070]
155140  Il23a; interleukin-23 subunit alpha precursor [KO:K05426]
156767  Tnfrsf1b; tumor necrosis factor receptor superfamily member 1B precursor [KO:K05141]
170819  Il24; interleukin-24 precursor [KO:K22668]
171040  Il11; interleukin-11 precursor [KO:K05417]
171054  Ccr4; C-C chemokine receptor type 4 [KO:K04179]
171056  Cx3cr1; CX3C chemokine receptor 1 [KO:K04192]
171060  Il13ra2; interleukin-13 receptor subunit alpha-2 precursor [KO:K05077]
171081  Csf2rb; cytokine receptor common subunit beta precursor [KO:K04738]
171106  Il1rl2; interleukin-1 receptor-like 2 precursor [KO:K05172]
171333  Il12rb1; interleukin-12 receptor subunit beta-1 precursor [KO:K05063]
171334  Il12rb2; interleukin-12 receptor subunit beta-2 precursor [KO:K05064]
171369  Cd40; tumor necrosis factor receptor superfamily member 5 precursor [KO:K03160]
171371  Xcl1; lymphotactin precursor [KO:K05507]
171499  Crlf2; cytokine receptor-like factor 2 precursor [KO:K05078]
171551  Cxcl3; C-X-C motif chemokine 3 precursor [KO:K05505]
171556  Prl5a1; prolactin-5A1 precursor [KO:K05439]
24335  Epo; erythropoietin precursor [KO:K05437]
24336  Epor; erythropoietin receptor precursor [KO:K05079]
24391  Gh1; somatotropin precursor [KO:K05438]
24481  Ifnb1; interferon beta precursor [KO:K05415]
24493  Il1a; interleukin-1 alpha [KO:K04383]
24494  Il1b; interleukin-1 beta [KO:K04519]
24495  Il3; interleukin-3 precursor [KO:K04736]
24497  Il5; interleukin-5 precursor [KO:K05428]
24498  Il6; interleukin-6 precursor [KO:K05405]
24499  Il6r; interleukin-6 receptor subunit alpha precursor [KO:K05055]
24500  Il9r; interleukin-9 receptor [KO:K05073]
24504  Inha; inhibin alpha chain precursor [KO:K05500]
24536  Lepr; leptin receptor precursor [KO:K05062]
245920  Cxcl10; C-X-C motif chemokine 10 precursor [KO:K12671]
245921  Acvr1c; activin receptor type-1C precursor [KO:K13568] [EC:2.7.11.30]
24596  Ngfr; tumor necrosis factor receptor superfamily member 16 precursor [KO:K02583]
245983  Il11ra1; interleukin-11 receptor subunit alpha precursor [KO:K05056]
246097  Fas; tumor necrosis factor receptor superfamily member 6 precursor [KO:K04390]
246144  Il3ra; interleukin-3 receptor subunit alpha precursor [KO:K04737]
246358  Ppbp; platelet basic protein precursor [KO:K10029]
24657  Prl6a1; prolactin-6A1 precursor [KO:K05439]
246759  Cxcl9; C-X-C motif chemokine 9 precursor [KO:K05416]
246775  Tnfsf10; tumor necrosis factor ligand superfamily member 10 [KO:K04721]
24683  Prl; prolactin precursor [KO:K05439]
24684  Prlr; prolactin receptor isoform a precursor [KO:K05081]
24770  Ccl2; C-C motif chemokine 2 precursor [KO:K14624]
24772  Cxcl12; stromal cell-derived factor 1 isoform beta precursor [KO:K10031]
24835  Tnf; tumor necrosis factor [KO:K03156]
24932  Cd4; T-cell surface glycoprotein CD4 precursor [KO:K06454]
25008  Lta; lymphotoxin-alpha precursor [KO:K05468]
25069  Tnfrsf8; tumor necrosis factor receptor superfamily member 8 precursor [KO:K05145]
25084  Il4r; interleukin-4 receptor subunit alpha precursor [KO:K05071]
25196  Inhbb; inhibin beta B chain precursor [KO:K22687]
25205  Il6st; interleukin-6 receptor subunit beta precursor [KO:K05060]
25235  Ghr; growth hormone receptor precursor [KO:K05080]
25237  Acvrl1; serine/threonine-protein kinase receptor R3 precursor [KO:K13594] [EC:2.7.11.30]
252833  Gdf7; growth/differentiation factor 7 isoform 2 precursor [KO:K20013]
252834  Gdf6; growth/differentiation factor 6 precursor [KO:K20012]
252835  Gdf5; growth/differentiation factor 5 preproprotein [KO:K04664]
252878  Tnfsf15; tumor necrosis factor ligand superfamily member 15 [KO:K05478]
25296  Bmp4; bone morphogenetic protein 4 precursor [KO:K04662]
252963  Il13ra1; interleukin-13 receptor subunit alpha-1 precursor [KO:K05076]
25325  Il10; interleukin-10 precursor [KO:K05443]
25341  Tnfrsf11b; tumor necrosis factor receptor superfamily member 11B precursor [KO:K05148]
25366  Acvr2b; activin receptor type-2B precursor [KO:K13596] [EC:2.7.11.30]
25378  Amh; muellerian-inhibiting factor precursor [KO:K04665]
25385  Faslg; tumor necrosis factor ligand superfamily member 6 [KO:K04389]
25466  Il1rap; interleukin-1 receptor accessory protein precursor [KO:K04723]
25542  Ccl3; C-C motif chemokine 3 precursor [KO:K05408]
25556  Il1rl1; interleukin-1 receptor-like 1 isoform Fit-1M precursor [KO:K05171]
25572  Tnfrsf4; tumor necrosis factor receptor superfamily member 4 precursor [KO:K05142]
25608  Lep; leptin precursor [KO:K05424]
25610  Csf3; granulocyte colony-stimulating factor precursor [KO:K05423]
25625  Tnfrsf1a; tumor necrosis factor receptor superfamily member 1A precursor [KO:K03158]
25644  Bmp6; bone morphogenetic protein 6 precursor [KO:K16620]
25647  Il7; interleukin-7 precursor [KO:K05431]
25663  Il1r1; interleukin-1 receptor type 1 precursor [KO:K04386]
25667  Bmp3; bone morphogenetic protein 3 precursor [KO:K05496]
25670  Il15; interleukin-15 preproprotein [KO:K05433]
25704  Il2ra; interleukin-2 receptor subunit alpha precursor [KO:K05068]
25707  Cntf; ciliary neurotrophic factor [KO:K05420]
25712  Ifng; interferon gamma precursor [KO:K04687]
25717  Tgfb3; transforming growth factor beta-3 proprotein preproprotein [KO:K13377]
25746  Il2rb; interleukin-2 receptor subunit beta precursor [KO:K05069]
282832  Ccr9; C-C chemokine receptor type 9 [KO:K04184]
287034  Tnfrsf17; tumor necrosis factor receptor superfamily member 17 [KO:K05153]
287287  Il4; interleukin-4 precursor [KO:K05430]
287437  Tnfsf13; tumor necrosis factor ligand superfamily member 13 [KO:K05475]
287561  Ccl7; C-C motif chemokine 7 precursor [KO:K05509]
287562  Ccl12; C-C motif chemokine ligand 12 precursor [KO:K14624]
287673  Ccr7; C-C chemokine receptor type 7 precursor [KO:K04182]
287910  Ccl6; C-C motif chemokine 6 precursor [KO:K05510]
288264  Ifnar1; interferon alpha/beta receptor 1 isoform 1 precursor [KO:K05130]
288593  Ccl24; C-C motif chemokine 24 precursor [KO:K21097]
288905  Il27ra; interleukin-27 receptor subunit alpha precursor [KO:K19598]
289635  Rell1; RELT-like protein 1 precursor [KO:K26541]
289747  Osm; oncostatin-M precursor [KO:K05418]
290300  Tnfrsf19; tumor necrosis factor receptor superfamily member 19 precursor [KO:K05155]
290921  Gdf2; growth/differentiation factor 2 precursor [KO:K05503]
29152  Mstn; growth/differentiation factor 8 precursor [KO:K05497]
29197  Il18; interleukin-18 [KO:K05482]
29200  Inhba; inhibin beta A chain preproprotein [KO:K04667]
29201  Ctf1; cardiotrophin-1 [KO:K05422]
29263  Acvr2a; activin receptor type-2A precursor [KO:K04670] [EC:2.7.11.30]
293515  Ctf2; cardiotrophin-2 precursor [KO:K24382]
29363  Cxcr5; C-X-C chemokine receptor type 5 [KO:K04190]
29373  Bmp2; bone morphogenetic protein 2 precursor [KO:K21283]
29381  Acvr1b; activin receptor type-1B precursor [KO:K13567] [EC:2.7.11.30]
29385  Cxcr2; C-X-C chemokine receptor type 2 [KO:K05050]
29397  Ccl11; eotaxin precursor [KO:K16597]
294503  Nodal; nodal homolog precursor [KO:K04666]
29454  Gdf11; growth/differentiation factor 11 precursor [KO:K22679]
29455  Gdf15; growth/differentiation factor 15 precursor [KO:K05504]
294797  Il7r; interleukin-7 receptor subunit alpha precursor [KO:K05072]
29530  Amhr2; anti-Muellerian hormone type-2 receptor precursor [KO:K04672] [EC:2.7.11.30]
29538  Ccl20; C-C motif chemokine 20 precursor [KO:K14625]
29591  Tgfbr1; TGF-beta receptor type-1 precursor [KO:K04674] [EC:2.7.11.30]
296541  Il36a; interleukin-36 alpha [KO:K05484]
296872  Eda2r; tumor necrosis factor receptor superfamily member 27 [KO:K05163]
297520  Il17rc; interleukin-17 receptor C precursor [KO:K05166]
297604  Ltbr; tumor necrosis factor receptor superfamily member 3 precursor [KO:K03159]
298006  Ccl21; C-C motif chemokine 21 precursor [KO:K16062]
298205  Ifna4; interferon, alpha 4 precursor [KO:K05414]
298210  Ifna5; interferon alpha-1 precursor [KO:K05414]
298213  Ifna2; interferon alpha family, gene 2 precursor [KO:K05414]
298518  Csf3r; granulocyte colony-stimulating factor receptor precursor [KO:K05061]
301066  Ccr8; C-C chemokine receptor type 8 [KO:K04183]
301086  Xcr1; chemokine XC receptor 1 [KO:K04193]
301088  Ccr1l1; C-C chemokine receptor 1-like protein 1 [KO:K04176]
301132  Cd70; CD70 antigen [KO:K05470]
301133  Tnfsf14; tumor necrosis factor ligand superfamily member 14 [KO:K05477]
301289  Il17a; interleukin-17A precursor [KO:K05489]
301291  Il17f; interleukin-17F precursor [KO:K05494]
301365  Il18r1; interleukin-18 receptor 1 precursor [KO:K05173]
302424  Eda; ectodysplasin-A [KO:K05480]
302965  Tnfrsf12a; tumor necrosis factor receptor superfamily member 12A precursor [KO:K05149]
304091  Il10rb; interleukin-10 receptor subunit beta precursor [KO:K05135]
305236  Cxcl11; C-X-C motif chemokine 11 precursor [KO:K12672]
306247  Il17rb; interleukin-17 receptor B isoform 1 [KO:K05165]
306351  Gdf1; embryonic growth/differentiation factor 1 precursor [KO:K05495]
306748  Cxcl14; C-X-C motif chemokine 14 precursor [KO:K10033]
307403  Csf1r; macrophage colony-stimulating factor 1 receptor precursor [KO:K05090] [EC:2.7.10.1]
308163  Ccr6; C-C chemokine receptor type 6 [KO:K04181]
308436  Cxcl17; C-X-C motif chemokine 17 precursor [KO:K22627]
308716  Il20ra; interleukin-20 receptor subunit alpha precursor [KO:K05136]
308977  Il21r; interleukin-21 receptor precursor [KO:K05075]
310132  Osmr; oncostatin-M-specific receptor subunit beta precursor [KO:K05057]
310738  Ngf; beta-nerve growth factor precursor [KO:K02582]
310914  Bmpr1b; bone morphogenetic protein receptor type-1B [KO:K13578] [EC:2.7.11.30]
311783  Il36rn; interleukin-36 receptor antagonist protein [KO:K05483]
312679  Il17ra; interleukin-17 receptor A [KO:K05164]
313152  Ifnk; interferon kappa precursor [KO:K05441]
313173  Cntfr; ciliary neurotrophic factor receptor subunit alpha precursor [KO:K05059]
315824  Bmp5; bone morphogenetic protein 5 precursor [KO:K04663]
316256  Tnfrsf21; tumor necrosis factor receptor superfamily member 21 precursor [KO:K05157]
353218  Tnfsf9; tumor necrosis factor ligand superfamily member 9 [KO:K05472]
360548  Tnfsf12; tumor necrosis factor ligand superfamily member 12 [KO:K05474]
360579  Ccl9; C-C motif chemokine 9 precursor [KO:K22671]
360697  Ifngr2; interferon gamma receptor 2 precursor [KO:K05133]
360750  Ccl25; C-C motif chemokine 25 precursor [KO:K13072]
360918  Pf4; platelet factor 4 precursor [KO:K05407]
361313  Rell2; RELT-like protein 2 [KO:K26541]
361615  Relt; tumor necrosis factor receptor superfamily member 19L precursor [KO:K05156]
361749  Il33; interleukin-33 [KO:K12967]
361795  Ltb; lymphotoxin-beta [KO:K03157]
362076  Il36b; interleukin-36 beta [KO:K05486]
362077  Il1f10; interleukin-1 family member 10 [KO:K05488]
362417  Il17re; interleukin-17 receptor E precursor [KO:K05168]
362505  Ccl27; C-C motif chemokine 27 [KO:K16598]
362506  Ccl19; C-C motif chemokine 19 precursor [KO:K05512]
362628  Ifnlr1; interferon lambda receptor 1 precursor [KO:K05140]
362629  Il22ra1; interleukin-22 receptor subunit alpha-1 [KO:K05138]
363682  Ccr10; C-C chemokine receptor type 10 [KO:K04185]
364031  Tnfsf18; tumor necrosis factor ligand superfamily member 18 [KO:K05479]
365368  Il27; interleukin-27 subunit alpha [KO:K22629]
365395  Clcf1; cardiotrophin-like cytokine factor 1 isoform 1 precursor [KO:K05421]
365581  Edar; tumor necrosis factor receptor superfamily member EDAR precursor [KO:K05162]
365769  Il21; interleukin-21 precursor [KO:K05434]
366455  Mpl; thrombopoietin receptor precursor [KO:K05082]
366518  Tnfrsf14; tumor necrosis factor receptor superfamily member 14 precursor [KO:K05152]
373540  Il18rap; interleukin-18 receptor accessory protein precursor [KO:K05174]
497942  Cxcl16; C-X-C motif chemokine 16 precursor [KO:K10035]
498206  Tnfrsf11a; tumor necrosis factor receptor superfamily member 11A precursor [KO:K05147]
498335  Cxcl13; C-X-C motif chemokine 13 isoform 2 precursor [KO:K10032]
498666  Tnfsf13b; tumor necrosis factor ligand superfamily member 13B [KO:K05476]
498951  Il34; interleukin-34 precursor [KO:K22633]
499744  Il36g; interleukin-36 gamma [KO:K05487]
500245  Bmp10; bone morphogenetic protein 10 precursor [KO:K22670]
500311  Gdf3; growth/differentiation factor 3 precursor [KO:K22672]
500318  Cd27; CD27 antigen precursor [KO:K05144]
500491  Ifna16l1; interferon, alpha 16-like 1 precursor [KO:K05414]
500590  Tnfrsf9; tumor necrosis factor receptor superfamily member 9 precursor [KO:K05146]
500592  Tnfrsf25; tumor necrosis factor receptor superfamily member 25 precursor [KO:K05160]
500598  Tnfrsf18; tumor necrosis factor receptor superfamily member 18 precursor [KO:K05154]
500836  Il22; interleukin-22 precursor [KO:K05445]
500910  Tnfrsf13c; tumor necrosis factor receptor superfamily member 13C [KO:K05151]
501043  Il20rb; interleukin-20 receptor subunit beta [KO:K05137]
501996  Il25; interleukin-25 [KO:K05493]
502959  Ifna1l1; similar to put. precursor MuIFN-alpha 5 precursor [KO:K05414]
502961  Ifna4l2; similar to Interferon alpha-1 precursor [KO:K05414]
54258  Cxcr1; C-X-C chemokine receptor type 1 [KO:K04175]
57301  Ccr1; C-C chemokine receptor type 1 [KO:K04176]
59086  Tgfb1; transforming growth factor beta-1 proprotein precursor [KO:K13375]
59302  Bmp15; bone morphogenetic protein 15 precursor [KO:K05498]
59304  Gdf9; growth/differentiation factor 9 precursor [KO:K22673]
60463  Ccr2; C-C chemokine receptor type 2 [KO:K04177]
60582  Il1rn; interleukin-1 receptor antagonist protein precursor [KO:K05481]
60584  Lif; leukemia inhibitory factor precursor [KO:K05419]
60628  Cxcr4; C-X-C chemokine receptor type 4 [KO:K04189]
60665  Cxcl6; C-X-C motif chemokine 5 precursor [KO:K05506]
64546  Il12b; interleukin-12 subunit beta precursor [KO:K05425]
64549  Inhbc; inhibin beta C chain precursor [KO:K22688]
652957  Csf2ra; granulocyte-macrophage colony-stimulating factor receptor subunit alpha precursor [KO:K05066]
679119  Bmp8b; bone morphogenetic protein 8B isoform X2 [KO:K16622]
680609  Ebi3; interleukin-27 subunit beta precursor [KO:K24476]
680931  Bmp8a; bone morphogenetic protein 8A precursor [KO:K16622]
681112  Il20; interleukin-20 [KO:K22667]
681145  Il19; interleukin-19 [KO:K05444]
683163  Tnfsf8; tumor necrosis factor ligand superfamily member 8 [KO:K05471]
685243  Ackr4; atypical chemokine receptor 4 [KO:K04186]
685840  Ifnl3; interferon lambda-2 [KO:K22669]
685958  Ccl26; C-C motif chemokine 26 precursor [KO:K21096]
686326  Ifnar2; interferon alpha and beta receptor subunit 2 isoform 1 precursor [KO:K05131]
688605  Ccl1; C-C motif chemokine 1 precursor [KO:K05514]
688621  Tslp; thymic stromal lymphopoietin isoform X1 [KO:K05436]
688622  Il31ra; interleukin-31 receptor subunit alpha precursor [KO:K22630]
689932  Il23r; interleukin-23 receptor isoform X1 [KO:K05065]
690028  Il31; interleukin-31 [KO:K22631]
690369  Il15ra; interleukin-15 receptor subunit alpha precursor [KO:K05074]
690894  Ifna1; interferon alpha family, gene 5 precursor [KO:K05414]
691516  Il17c; interleukin-17C precursor [KO:K05491]
691799  Il17d; interleukin-17D precursor [KO:K05492]
78965  Csf1; macrophage colony-stimulating factor 1 precursor [KO:K05453]
79216  Gdf10; growth/differentiation factor 10 precursor [KO:K22674]
79558  Acvr1; activin receptor type-1 precursor [KO:K04675] [EC:2.7.11.30]
81503  Cxcl1; growth-regulated alpha protein precursor [KO:K05505]
81507  Bmpr1a; bone morphogenetic protein receptor type-1A precursor [KO:K04673] [EC:2.7.11.30]
81680  Lifr; leukemia inhibitory factor receptor precursor [KO:K05058]
81780  Ccl5; C-C motif chemokine 5 precursor [KO:K12499]
81809  Tgfb2; transforming growth factor beta-2 proprotein precursor [KO:K13376]
81810  Tgfbr2; TGF-beta receptor type-2 precursor [KO:K04388] [EC:2.7.11.30]
81811  Thpol1; thrombopoietin precursor [KO:K06854]
83711  Inhbe; inhibin beta E chain precursor [KO:K22689]
84348  Ackr3; atypical chemokine receptor 3 [KO:K04304]
84349  Cd40lg; CD40 ligand [KO:K03161]
84405  Il12a; interleukin-12 subunit alpha precursor [KO:K05406]
84475  Cxcr3; C-X-C chemokine receptor type 3 [KO:K04188]
85272  Bmp7; bone morphogenetic protein 7 precursor [KO:K16621]
89808  Cx3cl1; fractalkine precursor [KO:K05508]
89814  Tnfsf4; tumor necrosis factor ligand superfamily member 4 [KO:K05469]
Reference
PMID:24892271
  Authors
Turner MD, Nedjai B, Hurst T, Pennington DJ
  Title
Cytokines and chemokines: At the crossroads of cell signalling and inflammatory disease.
  Journal
Biochim Biophys Acta 1843:2563-2582 (2014)
DOI:10.1016/j.bbamcr.2014.05.014
Reference
PMID:21106488
  Authors
Brocker C, Thompson D, Matsumoto A, Nebert DW, Vasiliou V
  Title
Evolutionary divergence and functions of the human interleukin (IL) gene family.
  Journal
Hum Genomics 5:30-55 (2010)
DOI:10.1186/1479-7364-5-1-30
Reference
PMID:27577879
  Authors
Akdis M, Aab A, Altunbulakli C, Azkur K, Costa RA, Crameri R, Duan S, Eiwegger T, Eljaszewicz A, Ferstl R, Frei R, Garbani M, Globinska A, Hess L, Huitema C, Kubo T, Komlosi Z, Konieczna P, Kovacs N, Kucuksezer UC, Meyer N, Morita H, Olzhausen J, O'Mahony L, Pezer M, Prati M, Rebane A, Rhyner C, Rinaldi A, Sokolowska M, Stanic B, Sugita K, Treis A, van de Veen W, Wanke K, Wawrzyniak M, Wawrzyniak P, Wirz OF, Zakzuk JS, Akdis CA
  Title
Interleukins (from IL-1 to IL-38), interferons, transforming growth factor beta, and TNF-alpha: Receptors, functions, and roles in diseases.
  Journal
J Allergy Clin Immunol 138:984-1010 (2016)
DOI:10.1016/j.jaci.2016.06.033
Reference
PMID:15500860
  Authors
Boulanger MJ, Garcia KC
  Title
Shared cytokine signaling receptors: structural insights from the gp130 system.
  Journal
Adv Protein Chem 68:107-46 (2004)
DOI:10.1016/S0065-3233(04)68004-1
Reference
PMID:16034365
  Authors
Allan SM, Tyrrell PJ, Rothwell NJ
  Title
Interleukin-1 and neuronal injury.
  Journal
Nat Rev Immunol 5:629-40 (2005)
DOI:10.1038/nri1664
Reference
PMID:23847622
  Authors
Lopetuso LR, Chowdhry S, Pizarro TT
  Title
Opposing Functions of Classic and Novel IL-1 Family Members in Gut Health and Disease.
  Journal
Front Immunol 4:181 (2013)
DOI:10.3389/fimmu.2013.00181
Reference
PMID:21349428
  Authors
Iwakura Y, Ishigame H, Saijo S, Nakae S
  Title
Functional specialization of interleukin-17 family members.
  Journal
Immunity 34:149-62 (2011)
DOI:10.1016/j.immuni.2011.02.012
Reference
PMID:17530315
  Authors
Fischer P, Hilfiker-Kleiner D
  Title
Survival pathways in hypertrophy and heart failure: the gp130-STAT3 axis.
  Journal
Basic Res Cardiol 102:279-97 (2007)
DOI:10.1007/s00395-007-0658-z
Reference
PMID:24381786
  Authors
Richards CD
  Title
The enigmatic cytokine oncostatin m and roles in disease.
  Journal
ISRN Inflamm 2013:512103 (2013)
DOI:10.1155/2013/512103
Reference
PMID:18926762
  Authors
Zhang Q, Putheti P, Zhou Q, Liu Q, Gao W
  Title
Structures and biological functions of IL-31 and IL-31 receptors.
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Cytokine Growth Factor Rev 19:347-56 (2008)
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