KEGG   PATHWAY: scam04010
Entry
scam04010                   Pathway                                
Name
MAPK signaling pathway - Struthio camelus australis (South African ostrich)
Description
The mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in various cellular functions, including cell proliferation, differentiation and migration. Mammals express at least four distinctly regulated groups of MAPKs, extracellular signal-related kinases (ERK)-1/2, Jun amino-terminal kinases (JNK1/2/3), p38 proteins (p38alpha/beta/gamma/delta) and ERK5, that are activated by specific MAPKKs: MEK1/2 for ERK1/2, MKK3/6 for the p38, MKK4/7 (JNKK1/2) for the JNKs, and MEK5 for ERK5. Each MAPKK, however, can be activated by more than one MAPKKK, increasing the complexity and diversity of MAPK signalling. Presumably each MAPKKK confers responsiveness to distinct stimuli. For example, activation of ERK1/2 by growth factors depends on the MAPKKK c-Raf, but other MAPKKKs may activate ERK1/2 in response to pro-inflammatory stimuli.
Class
Environmental Information Processing; Signal transduction
Pathway map
scam04010  MAPK signaling pathway
scam04010

Disease
H02157  Short-rib thoracic dysplasia
Other DBs
GO: 0000165
Organism
Struthio camelus australis (South African ostrich) [GN:scam]
Gene
104137877  PDGFB; platelet-derived growth factor subunit B isoform X1 [KO:K17386]
104137883  ATF4; cyclic AMP-dependent transcription factor ATF-4 [KO:K04374]
104137958  TAB1; TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 [KO:K04403]
104137959  CACNA1I; LOW QUALITY PROTEIN: voltage-dependent T-type calcium channel subunit alpha-1I [KO:K04856]
104138015  EGF; pro-epidermal growth factor isoform X1 [KO:K04357]
104138161  FGF8; fibroblast growth factor 8 [KO:K04358]
104138216  FGFR4; fibroblast growth factor receptor 4 [KO:K05095] [EC:2.7.10.1]
104138345  FGF20; fibroblast growth factor 20 [KO:K04358]
104138549  KDR; vascular endothelial growth factor receptor 2 [KO:K05098] [EC:2.7.10.1]
104138567  GRB2; growth factor receptor-bound protein 2 [KO:K04364]
104138636  [KO:K04386]
104138710  MAP4K4; LOW QUALITY PROTEIN: mitogen-activated protein kinase kinase kinase kinase 4 [KO:K04407] [EC:2.7.11.1]
104138745  CACNB4; voltage-dependent L-type calcium channel subunit beta-4 isoform X1 [KO:K04865]
104138865  MAPK1; LOW QUALITY PROTEIN: mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
104138943  PAK2; serine/threonine-protein kinase PAK 2 [KO:K04410] [EC:2.7.11.1]
104139169  PRKCB; protein kinase C beta type [KO:K19662] [EC:2.7.11.13]
104139179  CACNG3; voltage-dependent calcium channel gamma-3 subunit [KO:K04868]
104139220  MAP2K5; dual specificity mitogen-activated protein kinase kinase 5 isoform X1 [KO:K04463] [EC:2.7.12.2]
104139226  MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 isoform X1 [KO:K04368] [EC:2.7.12.2]
104139269  PTPN7; tyrosine-protein phosphatase non-receptor type 7 isoform X1 [KO:K18019] [EC:3.1.3.48]
104139284  CACNA1S; voltage-dependent L-type calcium channel subunit alpha-1S [KO:K04857]
104139401  MAPK13; mitogen-activated protein kinase 13 [KO:K04441] [EC:2.7.11.24]
104139403  MAPK14; mitogen-activated protein kinase 14 [KO:K04441] [EC:2.7.11.24]
104139422  DUSP7; dual specificity protein phosphatase 7 [KO:K04459] [EC:3.1.3.16 3.1.3.48]
104139531  PDGFRA; platelet-derived growth factor receptor alpha [KO:K04363] [EC:2.7.10.1]
104139533  KIT; mast/stem cell growth factor receptor Kit [KO:K05091] [EC:2.7.10.1]
104139584  FGF5; fibroblast growth factor 5 [KO:K04358]
104139599  MAP3K2; mitogen-activated protein kinase kinase kinase 2 isoform X1 [KO:K04420] [EC:2.7.11.25]
104139604  MRAS; ras-related protein M-Ras isoform X1 [KO:K07831]
104139746  TRAF2; TNF receptor-associated factor 2 isoform X1 [KO:K03173] [EC:2.3.2.27]
104139778  CACNA1B; voltage-dependent N-type calcium channel subunit alpha-1B isoform X1 [KO:K04849]
104140173  EFNA5; ephrin-A5 [KO:K05462]
104140194  RAC3; ras-related C3 botulinum toxin substrate 3 isoform X1 [KO:K07861]
104140308  TGFB2; transforming growth factor beta-2 [KO:K13376]
104140318  DUSP10; dual specificity protein phosphatase 10 [KO:K20216] [EC:3.1.3.16 3.1.3.48]
104140441  FIGF; vascular endothelial growth factor D [KO:K05449]
104140467  RPS6KA3; ribosomal protein S6 kinase alpha-3 [KO:K04373] [EC:2.7.11.1]
104140561  FGF10; fibroblast growth factor 10 isoform X1 [KO:K04358]
104140707  PTPRR; receptor-type tyrosine-protein phosphatase R [KO:K04458] [EC:3.1.3.48]
104141153  AKT2; RAC-beta serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
104141200  [KO:K04855]
104141238  DUSP3; dual specificity protein phosphatase 3 [KO:K17614] [EC:3.1.3.16 3.1.3.48]
104141399  PPM1A; protein phosphatase 1A [KO:K04457] [EC:3.1.3.16]
104141575  PGF; placenta growth factor [KO:K16859]
104141645  TAOK3; serine/threonine-protein kinase TAO3 isoform X1 [KO:K04429] [EC:2.7.11.1]
104141696  STK4; serine/threonine-protein kinase 4 [KO:K04411]
104141776  PPP3CB; serine/threonine-protein phosphatase 2B catalytic subunit beta isoform isoform X1 [KO:K04348] [EC:3.1.3.16]
104141812  NFKB2; nuclear factor NF-kappa-B p100 subunit [KO:K04469]
104142047  RAP1B; ras-related protein Rap-1b [KO:K07836]
104142191  NRK; nik-related protein kinase isoform X1 [KO:K04407] [EC:2.7.11.1]
104142203  PDGFRB; platelet-derived growth factor receptor beta [KO:K05089] [EC:2.7.10.1]
104142216  CSF1R; macrophage colony-stimulating factor 1 receptor [KO:K05090] [EC:2.7.10.1]
104142243  FLT4; LOW QUALITY PROTEIN: vascular endothelial growth factor receptor 3 [KO:K05097] [EC:2.7.10.1]
104142260  MAPK8IP3; C-Jun-amino-terminal kinase-interacting protein 3 [KO:K04436]
104142306  RAP1A; ras-related protein Rap-1A [KO:K04353]
104142331  MAPKAPK2; MAP kinase-activated protein kinase 2 [KO:K04443] [EC:2.7.11.1]
104142339  ELK4; ETS domain-containing protein Elk-4 isoform X1 [KO:K04376]
104142361  NGF; beta-nerve growth factor [KO:K02582]
104142365  NRAS; GTPase NRas [KO:K07828]
104142382  MAPK9; mitogen-activated protein kinase 9 isoform X1 [KO:K04440] [EC:2.7.11.24]
104142447  [KO:K04459] [EC:3.1.3.16 3.1.3.48]
104142462  DUSP1; dual specificity protein phosphatase 1 [KO:K21278] [EC:3.1.3.16 3.1.3.48]
104142613  PLA2G4A; cytosolic phospholipase A2 [KO:K16342] [EC:3.1.1.4]
104142697  FASLG; tumor necrosis factor ligand superfamily member 6 [KO:K04389]
104142729  CACNA1E; voltage-dependent R-type calcium channel subunit alpha-1E [KO:K04852]
104142946  SRF; serum response factor isoform X1 [KO:K04378]
104143004  PRKACB; cAMP-dependent protein kinase catalytic subunit beta isoform X1 [KO:K04345] [EC:2.7.11.11]
104143275  CACNB2; voltage-dependent L-type calcium channel subunit beta-2 isoform X1 [KO:K04863]
104143307  MECOM; MDS1 and EVI1 complex locus protein EVI1 isoform X1 [KO:K04462] [EC:2.1.1.367]
104143515  HSPA8; heat shock cognate 71 kDa protein [KO:K03283]
104143610  MKNK1; MAP kinase-interacting serine/threonine-protein kinase 1 isoform X1 [KO:K04372] [EC:2.7.11.1]
104143715  HRAS; GTPase HRas [KO:K02833]
104143748  INS; insulin [KO:K04526]
104143761  STMN1; stathmin [KO:K04381]
104143763  PTPN5; tyrosine-protein phosphatase non-receptor type 5 isoform X1 [KO:K18018] [EC:3.1.3.48]
104143779  DUSP8; dual specificity protein phosphatase 8 [KO:K04459] [EC:3.1.3.16 3.1.3.48]
104143784  IGF2; insulin-like growth factor II [KO:K13769]
104143845  KITLG; kit ligand [KO:K05461]
104143881  DUSP6; dual specificity protein phosphatase 6 [KO:K21946] [EC:3.1.3.16 3.1.3.48]
104144138  MAP3K7; mitogen-activated protein kinase kinase kinase 7 isoform X1 [KO:K04427] [EC:2.7.11.25]
104144401  FGF6; fibroblast growth factor 6 [KO:K04358]
104144404  FGF23; fibroblast growth factor 23 [KO:K22428]
104144412  NTF3; neurotrophin-3 isoform X1 [KO:K04356]
104144489  AKT1; RAC-alpha serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
104144580  TGFB3; transforming growth factor beta-3 [KO:K13377]
104144707  HGF; hepatocyte growth factor [KO:K05460]
104144708  CACNA2D1; voltage-dependent calcium channel subunit alpha-2/delta-1 [KO:K04858]
104144724  CRK; adapter molecule crk [KO:K04438]
104144774  MAP3K3; mitogen-activated protein kinase kinase kinase 3 isoform X1 [KO:K04421] [EC:2.7.11.25]
104144795  STK3; serine/threonine-protein kinase 3 [KO:K04412]
104144997  PPM1B; protein phosphatase 1B isoform X1 [KO:K04461] [EC:3.1.3.16]
104145156  MAPK10; mitogen-activated protein kinase 10 [KO:K04440] [EC:2.7.11.24]
104145158  TGFBR1; TGF-beta receptor type-1 [KO:K04674] [EC:2.7.11.30]
104145212  VEGFC; vascular endothelial growth factor C isoform X1 [KO:K05449]
104145229  CASP3; caspase-3 isoform X1 [KO:K02187] [EC:3.4.22.56]
104145497  ANGPT2; angiopoietin-2 isoform X1 [KO:K05466]
104145513  SOS2; son of sevenless homolog 2 [KO:K03099]
104145525  MAP3K12; mitogen-activated protein kinase kinase kinase 12 [KO:K04423] [EC:2.7.11.25]
104145570  [KO:K08018]
104145629  PDGFC; platelet-derived growth factor C [KO:K05450]
104145644  MAPKAPK5; MAP kinase-activated protein kinase 5 isoform X1 [KO:K04442] [EC:2.7.11.1]
104145645  [KO:K04388] [EC:2.7.11.30]
104145759  MAP2K2; dual specificity mitogen-activated protein kinase kinase 2 isoform X1 [KO:K04369] [EC:2.7.12.2]
104145788  FGFR2; fibroblast growth factor receptor 2 isoform X1 [KO:K05093] [EC:2.7.10.1]
104146010  MAPK8; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
104146044  FAS; tumor necrosis factor receptor superfamily member 6 [KO:K04390]
104146182  INSR; insulin receptor [KO:K04527] [EC:2.7.10.1]
104146290  TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein [KO:K03171]
104146403  NFATC3; nuclear factor of activated T-cells, cytoplasmic 3 [KO:K17333]
104146435  PDGFD; platelet-derived growth factor D isoform X1 [KO:K05450]
104146608  DUSP16; dual specificity protein phosphatase 16 [KO:K04459] [EC:3.1.3.16 3.1.3.48]
104146717  CACNA1G; voltage-dependent T-type calcium channel subunit alpha-1G isoform X1 [KO:K04854]
104146769  CACNG4; voltage-dependent calcium channel gamma-4 subunit [KO:K04869]
104146770  CACNG5; voltage-dependent calcium channel gamma-5 subunit [KO:K04870]
104146828  CACNG1; voltage-dependent calcium channel gamma-1 subunit [KO:K04866]
104146830  PRKCA; protein kinase C alpha type [KO:K02677] [EC:2.7.11.13]
104146835  MAP2K6; dual specificity mitogen-activated protein kinase kinase 6 [KO:K04433] [EC:2.7.12.2]
104146859  MAP3K1; LOW QUALITY PROTEIN: mitogen-activated protein kinase kinase kinase 1 [KO:K04416] [EC:2.7.11.25]
104146982  [KO:K04453]
104147043  EGFR; epidermal growth factor receptor isoform X1 [KO:K04361] [EC:2.7.10.1]
104147075  BDNF; brain-derived neurotrophic factor isoform X1 [KO:K04355]
104147176  MAP3K8; mitogen-activated protein kinase kinase kinase 8 [KO:K04415] [EC:2.7.11.25]
104147228  [KO:K04360] [EC:2.7.10.1]
104147270  CACNA1C; LOW QUALITY PROTEIN: voltage-dependent L-type calcium channel subunit alpha-1C [KO:K04850]
104147350  IGF1; insulin-like growth factor I isoform X1 [KO:K05459]
104147383  CACNA2D4; voltage-dependent calcium channel subunit alpha-2/delta-4 [KO:K04861]
104147394  BRAF; serine/threonine-protein kinase B-raf [KO:K04365] [EC:2.7.11.1]
104147407  PPP5C; serine/threonine-protein phosphatase 5 [KO:K04460] [EC:3.1.3.16]
104147419  TEK; LOW QUALITY PROTEIN: angiopoietin-1 receptor [KO:K05121] [EC:2.7.10.1]
104147506  CDC25B; M-phase inducer phosphatase 2 [KO:K05866] [EC:3.1.3.48]
104147585  MAP2K4; dual specificity mitogen-activated protein kinase kinase 4 isoform X1 [KO:K04430] [EC:2.7.12.2]
104147799  [KO:K17534] [EC:2.7.11.25]
104147828  GDNF; glial cell line-derived neurotrophic factor [KO:K05452]
104147858  MAPKAPK3; MAP kinase-activated protein kinase 3 [KO:K04444] [EC:2.7.11.1]
104147923  RPS6KA2; ribosomal protein S6 kinase alpha-2 isoform X1 [KO:K04373] [EC:2.7.11.1]
104148037  IL1B; interleukin-1 beta [KO:K04519]
104148096  CACNB1; LOW QUALITY PROTEIN: voltage-dependent L-type calcium channel subunit beta-1 [KO:K04862]
104148253  FGF7; fibroblast growth factor 7 [KO:K04358]
104148380  IGF1R; insulin-like growth factor 1 receptor [KO:K05087] [EC:2.7.10.1]
104148531  [KO:K04424] [EC:2.7.11.25]
104148543  ATF2; cyclic AMP-dependent transcription factor ATF-2 [KO:K04450]
104148747  FGFR1; LOW QUALITY PROTEIN: fibroblast growth factor receptor 1 [KO:K04362] [EC:2.7.10.1]
104148759  IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [KO:K07209] [EC:2.7.11.10]
104148783  MYD88; myeloid differentiation primary response protein MyD88 [KO:K04729]
104148795  IL1RAP; interleukin-1 receptor accessory protein isoform X1 [KO:K04723]
104148951  MAPT; microtubule-associated protein tau isoform X1 [KO:K04380]
104148985  RPS6KA1; ribosomal protein S6 kinase alpha-1 isoform X1 [KO:K04373] [EC:2.7.11.1]
104149443  ANGPT1; angiopoietin-1 [KO:K05465]
104149540  CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1 [KO:K04467] [EC:2.7.11.10]
104149649  RAC1; ras-related C3 botulinum toxin substrate 1 [KO:K04392]
104149676  FGF2; fibroblast growth factor 2 [KO:K18497]
104149874  DUSP4; dual specificity protein phosphatase 4 [KO:K04459] [EC:3.1.3.16 3.1.3.48]
104149939  [KO:K09784]
104149946  AREG; amphiregulin [KO:K09782]
104150004  NTRK2; BDNF/NT-3 growth factors receptor isoform X1 [KO:K04360] [EC:2.7.10.1]
104150063  AKT3; RAC-gamma serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
104150110  MEF2C; myocyte-specific enhancer factor 2C isoform X1 [KO:K04454]
104150199  RAC2; ras-related C3 botulinum toxin substrate 2 [KO:K07860]
104150209  CACNG2; voltage-dependent calcium channel gamma-2 subunit isoform X1 [KO:K04867]
104150283  GADD45G; growth arrest and DNA damage-inducible protein GADD45 gamma [KO:K04402]
104150358  PPP3CC; LOW QUALITY PROTEIN: serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform [KO:K04348] [EC:3.1.3.16]
104150403  [KO:K16342] [EC:3.1.1.4]
104150404  [KO:K16342] [EC:3.1.1.4]
104150405  [KO:K16342] [EC:3.1.1.4]
104150416  MAPK8IP1; C-Jun-amino-terminal kinase-interacting protein 1 [KO:K04434]
104150425  PLA2G4B; cytosolic phospholipase A2 beta [KO:K16342] [EC:3.1.1.4]
104150428  [KO:K16342] [EC:3.1.1.4]
104150429  [KO:K16342] [EC:3.1.1.4]
104150430  [KO:K16342] [EC:3.1.1.4]
104150431  [KO:K16342] [EC:3.1.1.4]
104150432  [KO:K16342] [EC:3.1.1.4]
104150433  [KO:K16342] [EC:3.1.1.4]
104150464  RRAS2; ras-related protein R-Ras2 [KO:K07830]
104150537  RASA1; ras GTPase-activating protein 1 [KO:K04352]
104150762  [KO:K04421] [EC:2.7.11.25]
104150824  MAP2K3; dual specificity mitogen-activated protein kinase kinase 3 isoform X1 [KO:K04432] [EC:2.7.12.2]
104150857  MAP3K14; mitogen-activated protein kinase kinase kinase 14 [KO:K04466] [EC:2.7.11.25]
104150953  [KO:K05096] [EC:2.7.10.1]
104151181  TAB2; TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 [KO:K04404]
104151229  [KO:K04429] [EC:2.7.11.1]
104151349  FGFR3; fibroblast growth factor receptor 3 isoform X1 [KO:K05094] [EC:2.7.10.1]
104151524  MAPK11; mitogen-activated protein kinase 11 [KO:K04441] [EC:2.7.11.24]
104151532  MAPK12; mitogen-activated protein kinase 12 [KO:K04441] [EC:2.7.11.24]
104151588  FLT3; receptor-type tyrosine-protein kinase FLT3 [KO:K05092] [EC:2.7.10.1]
104151612  FGF9; fibroblast growth factor 9 [KO:K04358]
104151645  FLT1; vascular endothelial growth factor receptor 1 [KO:K05096] [EC:2.7.10.1]
104151681  RASGRP3; ras guanyl-releasing protein 3 isoform X1 [KO:K12362]
104151745  VEGFA; vascular endothelial growth factor A [KO:K05448]
104151818  MAP4K3; mitogen-activated protein kinase kinase kinase kinase 3 isoform X1 [KO:K04406] [EC:2.7.11.1]
104151819  SOS1; son of sevenless homolog 1 [KO:K03099]
104151871  PPP3R1; calcineurin subunit B type 1 [KO:K06268]
104152239  CRKL; crk-like protein [KO:K04438]
104152347  RPS6KA6; ribosomal protein S6 kinase alpha-6 isoform X1 [KO:K04373] [EC:2.7.11.1]
104152391  [KO:K03283]
104152532  TGFBR2; TGF-beta receptor type-2 [KO:K04388] [EC:2.7.11.30]
104152622  RET; proto-oncogene tyrosine-protein kinase receptor Ret [KO:K05126] [EC:2.7.10.1]
104152703  RAF1; RAF proto-oncogene serine/threonine-protein kinase [KO:K04366] [EC:2.7.11.1]
104152729  CACNA2D3; voltage-dependent calcium channel subunit alpha-2/delta-3 isoform X1 [KO:K04860]
104152762  CACNA1D; voltage-dependent L-type calcium channel subunit alpha-1D [KO:K04851]
104152779  PAK1; serine/threonine-protein kinase PAK 1 [KO:K04409] [EC:2.7.11.1]
104152786  JUN; transcription factor AP-1 [KO:K04448]
104152832  MAP3K4; mitogen-activated protein kinase kinase kinase 4 [KO:K04428] [EC:2.7.11.25]
104152855  FGF19; fibroblast growth factor 19 [KO:K22603]
104152881  TRAF6; TNF receptor-associated factor 6 [KO:K03175] [EC:2.3.2.27]
104152892  FGF3; fibroblast growth factor 3 [KO:K04358]
104152904  RASGRF2; ras-specific guanine nucleotide-releasing factor 2 isoform X1 [KO:K12326]
104153020  ERBB4; receptor tyrosine-protein kinase erbB-4 [KO:K05085] [EC:2.7.10.1]
104153038  NFATC1; nuclear factor of activated T-cells, cytoplasmic 1 isoform X1 [KO:K04446]
104153171  MAP3K5; mitogen-activated protein kinase kinase kinase 5 [KO:K04426] [EC:2.7.11.25]
104153181  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 [KO:K04347]
104153228  RASA2; ras GTPase-activating protein 2 [KO:K08053]
104153326  IRAK4; LOW QUALITY PROTEIN: interleukin-1 receptor-associated kinase 4 [KO:K04733] [EC:2.7.11.1]
104153443  NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1 [KO:K02580]
104153493  LAMTOR3; ragulator complex protein LAMTOR3 [KO:K04370]
104153496  PPP3CA; serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform [KO:K04348] [EC:3.1.3.16]
104153533  MET; hepatocyte growth factor receptor [KO:K05099] [EC:2.7.10.1]
104153640  CDC42; cell division control protein 42 homolog isoform X1 [KO:K04393]
104153670  TNFRSF1A; tumor necrosis factor receptor superfamily member 1A [KO:K03158]
104153783  RPS6KA5; ribosomal protein S6 kinase alpha-5 isoform X1 [KO:K04445] [EC:2.7.11.1]
104153821  MAP3K9; mitogen-activated protein kinase kinase kinase 9 [KO:K04417] [EC:2.7.11.25]
104153876  RASGRP1; RAS guanyl-releasing protein 1 [KO:K04350]
104153963  GNA12; LOW QUALITY PROTEIN: guanine nucleotide-binding protein subunit alpha-12 [KO:K04346]
104153975  PDGFA; platelet-derived growth factor subunit A [KO:K04359]
104154040  FGF18; fibroblast growth factor 18 [KO:K04358]
104154112  KRAS; GTPase KRas isoform X1 [KO:K07827]
104154145  NF1; neurofibromin [KO:K08052]
104154155  NLK; serine/threonine-protein kinase NLK isoform X1 [KO:K04468] [EC:2.7.11.24]
104154207  MAP3K13; mitogen-activated protein kinase kinase kinase 13 isoform X1 [KO:K04422] [EC:2.7.11.25]
Compound
C00076  Calcium cation
C00165  Diacylglycerol
C00338  Lipopolysaccharide
C00575  3',5'-Cyclic AMP
C01245  D-myo-Inositol 1,4,5-trisphosphate
Reference
PMID:11749383
  Authors
Chen Z, Gibson TB, Robinson F, Silvestro L, Pearson G, Xu B, Wright A, Vanderbilt C, Cobb MH.
  Title
MAP kinases.
  Journal
Chem Rev 101:2449-76 (2001)
DOI:10.1021/cr000241p
Reference
PMID:12191611
  Authors
Tanoue T, Nishida E.
  Title
Docking interactions in the mitogen-activated protein kinase cascades.
  Journal
Pharmacol Ther 93:193-202 (2002)
DOI:10.1016/S0163-7258(02)00188-2
Reference
PMID:12947395
  Authors
Dent P, Yacoub A, Fisher PB, Hagan MP, Grant S.
  Title
MAPK pathways in radiation responses.
  Journal
Oncogene 22:5885-96 (2003)
DOI:10.1038/sj.onc.1206701
Reference
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pathway
scam04070  Phosphatidylinositol signaling system
scam04110  Cell cycle
scam04115  p53 signaling pathway
scam04210  Apoptosis
scam04310  Wnt signaling pathway
KO pathway
ko04010   

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