Entry Name Hormone signaling - Lemur catta (Ring-tailed lemur)
Class Environmental Information Processing; Signaling molecules and interactionBRITE hierarchy
Pathway map Organism Lemur catta (Ring-tailed lemur) [GN:
lcat ]
Gene 123620564 CRHR1; corticotropin-releasing factor receptor 1 isoform X1 [KO:K04578 ]
123620748 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 [KO:K04549 ]
123620957 STAT5B; signal transducer and activator of transcription 5B isoform X1 [KO:K11224 ]
123620960 STAT3; signal transducer and activator of transcription 3 isoform X1 [KO:K04692 ]
123620973 RAMP2; receptor activity-modifying protein 2 isoform X1 [KO:K08448 ]
123621953 SMAD4; mothers against decapentaplegic homolog 4 isoform X1 [KO:K04501 ]
123622057 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 [KO:K05858 ] [EC:3.1.4.11 ]
123622065 PLCB1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1 [KO:K05858 ] [EC:3.1.4.11 ]
123622596 SSTR4; LOW QUALITY PROTEIN: somatostatin receptor type 4 [KO:K04220 ]
123622795 GNB5; guanine nucleotide-binding protein subunit beta-5 [KO:K04539 ]
123623119 VIPR1; vasoactive intestinal polypeptide receptor 1 isoform X1 [KO:K04589 ]
123623249 GNAI2; guanine nucleotide-binding protein G(i) subunit alpha-2 [KO:K04630 ]
123623353 PTH1R; parathyroid hormone/parathyroid hormone-related peptide receptor isoform X1 [KO:K04585 ]
123623917 GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 [KO:K04544 ]
123623946 GIPR; gastric inhibitory polypeptide receptor isoform X1 [KO:K04580 ]
123624151 GNRHR; gonadotropin-releasing hormone receptor isoform X1 [KO:K04280 ]
123624366 PLCB2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X1 [KO:K05858 ] [EC:3.1.4.11 ]
123625313 GNAO1; guanine nucleotide-binding protein G(o) subunit alpha isoform X1 [KO:K04534 ]
123627584 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 [KO:K04541 ]
123629856 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1 [KO:K00922 ] [EC:2.7.1.153 ]
123630278 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922 ] [EC:2.7.1.153 ]
123630284 GNB4; guanine nucleotide-binding protein subunit beta-4 [KO:K04538 ]
123631427 GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 [KO:K04547 ]
123631510 GNA12; guanine nucleotide-binding protein subunit alpha-12 [KO:K04346 ]
123631640 GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 [KO:K04537 ]
123633190 GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 [KO:K04543 ]
123633362 GNA15; guanine nucleotide-binding protein subunit alpha-15 isoform X1 [KO:K04637 ]
123633418 GNA11; guanine nucleotide-binding protein subunit alpha-11 [KO:K04635 ]
123634506 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform [KO:K00922 ] [EC:2.7.1.153 ]
123635002 GNAI3; guanine nucleotide-binding protein G(i) subunit alpha-3 [KO:K04630 ]
123635536 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 [KO:K04347 ]
123636000 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 [KO:K04536 ]
123636434 FSHR; follicle-stimulating hormone receptor isoform X1 [KO:K04247 ]
123637148 GNG14; LOW QUALITY PROTEIN: putative guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-14 [KO:K04347 ]
123639706 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta [KO:K02649 ]
123640104 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 [KO:K07825 ]
123640470 RAPGEF3; rap guanine nucleotide exchange factor 3 isoform X1 [KO:K08014 ]
123640683 SLCO1C1; solute carrier organic anion transporter family member 1C1 isoform X1 [KO:K08747 ]
123641343 GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 [KO:K04540 ]
123641430 PLCB3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 isoform X1 [KO:K05858 ] [EC:3.1.4.11 ]
123642350 CCKBR; LOW QUALITY PROTEIN: gastrin/cholecystokinin type B receptor [KO:K04195 ]
123644016 SLC40A1; solute carrier family 40 member 1 isoform X1 [KO:K14685 ]
123644044 RAPGEF4; rap guanine nucleotide exchange factor 4 isoform X1 [KO:K04351 ]
123646016 GNA14; guanine nucleotide-binding protein subunit alpha-14 isoform X1 [KO:K04636 ]
123646308 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha [KO:K04634 ]
123646542 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 isoform X1 [KO:K04545 ]
123647043 CRHR2; corticotropin-releasing factor receptor 2 isoform X1 [KO:K04579 ]
123647150 GNAI1; guanine nucleotide-binding protein G(i) subunit alpha-1 [KO:K04630 ]
123647151 GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1 [KO:K04548 ]
123647191 VIPR2; vasoactive intestinal polypeptide receptor 2 isoform X1 [KO:K04590 ]
123647376 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 [KO:K04546 ]
123648081 NPR3; atrial natriuretic peptide receptor 3 isoform X1 [KO:K12325 ]
123648578 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649 ]
123649118 SMAD9; mothers against decapentaplegic homolog 9 isoform X1 [KO:K16791 ]
123650582 GNA13; guanine nucleotide-binding protein subunit alpha-13 isoform X1 [KO:K04639 ]
Compound C16048 Glucagon-like peptide 1
C16125 Calcitonin gene-related peptide 1
C16126 Calcitonin gene-related peptide 2
Reference Authors Trubacova R, Drastichova Z, Novotny J
Title Biochemical and physiological insights into TRH receptor-mediated signaling.
Journal Reference Authors Velez EJ, Unniappan S
Title A Comparative Update on the Neuroendocrine Regulation of Growth Hormone in Vertebrates.
Journal Reference Authors Kumar U
Title Somatostatin and Somatostatin Receptors in Tumour Biology.
Journal Reference Authors Kahnamouyi S, Nouri M, Farzadi L, Darabi M, Hosseini V, Mehdizadeh A
Title The role of mitogen-activated protein kinase-extracellular receptor kinase pathway in female fertility outcomes: a focus on pituitary gonadotropins regulation.
Journal Reference Authors Deussing JM, Chen A
Title The Corticotropin-Releasing Factor Family: Physiology of the Stress Response.
Journal Reference Authors Li Y, Yuan Q, He X, Zhang Y, You C, Wu C, Li J, Xu HE, Zhao LH
Title Molecular mechanism of prolactin-releasing peptide recognition and signaling via its G protein-coupled receptor.
Journal Reference Authors Wang C, Wang Q, Ji B, Pan Y, Xu C, Cheng B, Bai B, Chen J
Title The Orexin/Receptor System: Molecular Mechanism and Therapeutic Potential for Neurological Diseases.
Journal Reference Authors Bencze J, Pocsai K, Murnyak B, Gergely PA, Juhasz B, Szilvassy Z, Hortobagyi T
Title The Melanin-concentrating Hormone System in Human, Rodent and Avian Brain.
Journal Reference Authors Lin YT, Hsu KS
Title Oxytocin receptor signaling in the hippocampus: Role in regulating neuronal excitability, network oscillatory activity, synaptic plasticity and social memory.
Journal Reference Authors Perisic M, Woolcock K, Hering A, Mendel H, Muttenthaler M
Title Oxytocin and vasopressin signaling in health and disease.
Journal Reference Authors Che T, Roth BL
Title Molecular basis of opioid receptor signaling.
Journal Reference Authors Jing L, Zhang Q
Title Intrathyroidal feedforward and feedback network regulating thyroid hormone synthesis and secretion.
Journal Reference Authors Hu B, Li H, Zhang X
Title A Balanced Act: The Effects of GH-GHR-IGF1 Axis on Mitochondrial Function.
Journal Reference Authors Gloaguen P, Crepieux P, Heitzler D, Poupon A, Reiter E
Title Mapping the follicle-stimulating hormone-induced signaling networks.
Journal Reference Authors Johnson GP, Jonas KC
Title Mechanistic insight into how gonadotropin hormone receptor complexes direct signalingdagger.
Journal Reference Authors Wu CS, Cioanca AV, Gelmi MC, Wen L, Di Girolamo N, Zhu L, Natoli R, Conway RM, Petsoglou C, Jager MJ, McCluskey PJ, Madigan MC
Title The multifunctional human ocular melanocortin system.
Journal Reference Authors Standing D, Dandawate P, Anant S
Title Prolactin receptor signaling: A novel target for cancer treatment - Exploring anti-PRLR signaling strategies.
Journal Reference Authors Mendoza A, Hollenberg AN
Title New insights into thyroid hormone action.
Journal Reference Authors Gupta P, Furness SGB, Bittencourt L, Hare DL, Wookey PJ
Title Building the case for the calcitonin receptor as a viable target for the treatment of glioblastoma.
Journal Reference Authors Lombardi G, Ziemann E, Banfi G, Corbetta S
Title Physical Activity-Dependent Regulation of Parathyroid Hormone and Calcium-Phosphorous Metabolism.
Journal Reference Authors Mani I, Pandey KN
Title Emerging concepts of receptor endocytosis and concurrent intracellular signaling: Mechanisms of guanylyl cyclase/natriuretic peptide receptor-A activation and trafficking.
Journal Reference Authors Perez DM
Title alpha(1)-Adrenergic Receptors in Neurotransmission, Synaptic Plasticity, and Cognition.
Journal Reference Authors Feng Y, Lu Y
Title Immunomodulatory Effects of Dopamine in Inflammatory Diseases.
Journal Reference Authors Colin M, Delaitre C, Foulquier S, Dupuis F
Title The AT(1)/AT(2) Receptor Equilibrium Is a Cornerstone of the Regulation of the Renin Angiotensin System beyond the Cardiovascular System.
Journal Reference Authors Bogdan AR, Miyazawa M, Hashimoto K, Tsuji Y
Title Regulators of Iron Homeostasis: New Players in Metabolism, Cell Death, and Disease.
Journal Reference Authors Rajoria B, Zhang X, Yee D
Title IGF-1 Stimulates Glycolytic ATP Production in MCF-7L Cells.
Journal Reference Authors Arneth B, Arneth R, Shams M
Title Metabolomics of Type 1 and Type 2 Diabetes.
Journal Reference Authors Kajani S, Laker RC, Ratkova E, Will S, Rhodes CJ
Title Hepatic glucagon action: beyond glucose mobilization.
Journal Reference Authors Silvestro M, Iannone LF, Orologio I, Tessitore A, Tedeschi G, Geppetti P, Russo A
Title Migraine Treatment: Towards New Pharmacological Targets.
Journal Reference Authors Elliott S, Sinclair A, Collins H, Rice L, Jelkmann W
Title Progress in detecting cell-surface protein receptors: the erythropoietin receptor example.
Journal Reference Authors van Loenen MR, Geenen B, Arnoldussen IAC, Kiliaan AJ
Title Ghrelin as a prominent endocrine factor in stress-induced obesity.
Journal Reference Authors Zeng Q, Ou L, Wang W, Guo DY
Title Gastrin, Cholecystokinin, Signaling, and Biological Activities in Cellular Processes.
Journal Reference Authors Takei Y
Title Evolution of the membrane/particulate guanylyl cyclase: From physicochemical sensors to hormone receptors.
Journal Reference Authors Seino Y, Fukushima M, Yabe D
Title GIP and GLP-1, the two incretin hormones: Similarities and differences.
Journal Reference Authors Langer I, Jeandriens J, Couvineau A, Sanmukh S, Latek D
Title Signal Transduction by VIP and PACAP Receptors.
Journal Reference Authors Kitazawa T, Kaiya H
Title Motilin Comparative Study: Structure, Distribution, Receptors, and Gastrointestinal Motility.
Journal Reference Authors Cate RL
Title Anti-Mullerian Hormone Signal Transduction involved in Mullerian Duct Regression.
Journal Reference Authors Rettberg JR, Yao J, Brinton RD
Title Estrogen: a master regulator of bioenergetic systems in the brain and body.
Journal Reference Authors Prossnitz ER, Barton M
Title The G protein-coupled oestrogen receptor GPER in health and disease: an update.
Journal Reference Authors Roy B, Palaniyandi SS
Title Tissue-specific role and associated downstream signaling pathways of adiponectin.
Journal Reference Authors Liu J, Lai F, Hou Y, Zheng R
Title Leptin signaling and leptin resistance.
Journal Reference Authors Kuter DJ
Title Treatment of chemotherapy-induced thrombocytopenia in patients with non-hematologic malignancies.
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