KEGG ORTHOLOGY: K12169

ORTHOLOGY: K12169

Entry

K12169                      KO

Symbol

KPC1, RNF123

Name

Kip1 ubiquitination-promoting complex protein 1 [EC:2.3.2.27]

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system
    K12169  KPC1, RNF123; Kip1 ubiquitination-promoting complex protein 1
Enzymes [BR:ko01000]
2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.27  RING-type E3 ubiquitin transferase
     K12169  KPC1, RNF123; Kip1 ubiquitination-promoting complex protein 1
Ubiquitin system [BR:ko04121]
Ubiquitin ligases (E3)
  Single Ring-finger type E3
   Other single Ring-finger type E3
    K12169  KPC1, RNF123; Kip1 ubiquitination-promoting complex protein 1
  Multi subunit type E3
   KPC complex
    K12169  KPC1, RNF123; Kip1 ubiquitination-promoting complex protein 1

Genes

HSA:	63891(RNF123)

PTR:	743926(RNF123)

PPS:	100985440(RNF123)

GGO:	101141234(RNF123)

PON:	100434857(RNF123)

PPYG:

129033324(RNF123)

NLE:	100582102(RNF123)

HMH:	116473452(RNF123)

SSYN:

129481681(RNF123)

MCC:	705340(RNF123)

MCF:	102120447(RNF123)

MTHB:

126948628

MNI:	105480449(RNF123)

CSAB:

103227641(RNF123)

CATY:

105573698(RNF123)

PANU:

101017558(RNF123)

TGE:	112617334(RNF123)

MLEU:

105540342(RNF123)

RRO:	104667281(RNF123)

RBB:	108526981(RNF123)

TFN:	117081480(RNF123)

PTEH:

111555408(RNF123)

CANG:

105509697(RNF123)

CJC:	100397334(RNF123)

SBQ:	101042718(RNF123)

CIMI:

108284773(RNF123)

ANAN:

105727651(RNF123)

CSYR:

103265511(RNF123)

MMUR:

105874965(RNF123)

LCAT:

123623264(RNF123)

PCOQ:

105823689(RNF123)

OGA:	100957183(RNF123)

MMU:	84585(Rnf123)

MCAL:

110301127(Rnf123)

MPAH:

110328016(Rnf123)

RNO:	100190936(Rnf123)

MCOC:

116072011(Rnf123)

ANU:	117693198(Rnf123)

ASYL:

127688546(Rnf123)

MUN:	110564986(Rnf123)

CGE:	100760863(Rnf123)

MAUA:

101836810(Rnf123)

PROB:

127236688(Rnf123)

PLEU:

114705226(Rnf123)

PMAV:

102920814(Rnf123)

MORG:

121464196(Rnf123)

MFOT:

126499807

AAMP:

119809746(Rnf123)

NGI:	103750181(Rnf123)

HGL:	101717442(Rnf123)

CPOC:

100730766(Rnf123)

CCAN:

109692696(Rnf123)

DORD:

105994574(Rnf123)

DSP:	122095639(Rnf123)

DMER:

138815839 138824083

PLOP:

125342557(Rnf123)

NCAR:

124993378

MMMA:

107143472(Rnf123)

ITI:	101969880(Rnf123)

OCU:

100337984

OPI:	101527371(RNF123)

OCZ:	121165707(RNF123)

TUP:	102482987(RNF123)

GVR:	103589548(RNF123)

CFA:	484767(RNF123)

CLUD:

112665790(RNF123)

VVP:	112911375(RNF123)

VLG:	121496039(RNF123)

NPO:	129521847(RNF123)

AML:	100475229(RNF123)

UMR:	103675096(RNF123)

UAH:	113256882(RNF123)

UAR:	123798666(RNF123)

ELK:

111143774

LLV:

125079981

MPUF:

101676335(RNF123)

MNP:	132011325(RNF123)

MLK:	131823934(RNF123)

NVS:	122909419(RNF123)

ORO:	101386583(RNF123)

EJU:	114224994(RNF123)

ZCA:	113916810(RNF123)

MLX:	118005199(RNF123)

NSU:	110577542(RNF123)

LWW:

102725814

FCA:	101086379(RNF123)

PYU:	121011203(RNF123)

PCOO:

112852553(RNF123)

PBG:	122488714(RNF123)

PVIV:

125160670(RNF123)

LRUF:

124523145

LGF:	123607492(RNF123)

AJU:

106979190

PTG:	102954474(RNF123)

PPAD:

109247809(RNF123)

PUC:

125929354

PLEZ:

122214348(RNF123)

HHV:	120229401(RNF123)

BTA:	514160(RNF123)

BOM:	102269626(RNF123)

BIU:	109575996(RNF123)

BBUB:

102406777(RNF123)

BBIS:

104997290(RNF123)

CHX:	102179711(RNF123)

OAS:	101117200(RNF123)

BTAX:

128045454(RNF123)

CSUM:

138087488(RNF123)

ODA:	120868219(RNF123)

CCAD:

122425033(RNF123)

MREE:

136166822(RNF123)

OVR:	110152357(RNF123)

MBEZ:

129547842(RNF123)

SSC:	100513177(RNF123)

CFR:	102505148(RNF123)

CBAI:

105080252(RNF123)

CDK:	105087669(RNF123)

VPC:	102536919(RNF123)

BACU:

103017212(RNF123)

BMUS:

118903751(RNF123)

LVE:	103078591(RNF123)

OOR:	101276983(RNF123)

LALB:

132527004(RNF123)

GMF:	115858863(RNF123)

DDP:	132432297(RNF123)

DLE:	111174386(RNF123)

PCAD:

102979149(RNF123)

PSIU:

116761693(RNF123)

PPHC:

136128968(RNF123)

NASI:

112395063(RNF123)

ECB:	100053010(RNF123)

EPZ:	103553420(RNF123)

EAI:	106830696(RNF123)

MYB:	102261468(RNF123)

MYD:	102769340(RNF123)

MMYO:

118668471(RNF123)

MLF:	102437381(RNF123)

MDT:	132215848(RNF123)

MYUM:

138992461(RNF123)

PKL:	118715661(RNF123)

EFUS:

103298769(RNF123)

MNA:	107529455(RNF123)

DRO:	112309567(RNF123)

SHON:

118989469(RNF123)

AJM:	119036672(RNF123)

PDIC:

114501398(RNF123)

PHAS:

123830426(RNF123)

MMF:	118633157(RNF123)

PPAM:

129087697(RNF123)

HAI:	109375965(RNF123)

RFQ:	117036803(RNF123)

PALE:

102894058(RNF123)

PGIG:

120582357(RNF123)

PVP:	105302423(RNF123)

RAY:	107513355(RNF123)

MJV:	108393339(RNF123)

TOD:	119260260(RNF123)

SARA:

101557818(RNF123)

SFUM:

130037291(RNF123)

SETR:

126014116(RNF123)

LAV:	100675372(RNF123)

TMU:

101359500

ETF:	101659887(RNF123)

DNM:	101445253(RNF123)

MDO:	100028024(RNF123)

GAS:	123248810(RNF123)

SHR:	100923234(RNF123)

AFZ:

127554671

PCW:	110217032(RNF123)

TVP:	118830911(RNF123)

PBRV:

138167083(RNF123)

MLAO:

141495992(RNF123)

OAA:	100089761(RNF123)

TACU:

119950066(RNF123)

GGA:	415923(RNF123)

PCOC:

116241091(RNF123)

MGP:	100545952(RNF123) 104913098

CJO:	107319585(RNF123)

TPAI:

128078283(RNF123)

LMUT:

125698534(RNF123)

NMEL:

110405003(RNF123)

APLA:

101792473(RNF123)

ACYG:

106048753(RNF123)

CATA:

118253678(RNF123)

AFUL:

116492970(RNF123)

TGU:	100224034(RNF123)

LSR:	110469934(RNF123)

SCAN:

103817121(RNF123)

PMOA:

120495755(RNF123)

OTC:	121347196(RNF123)

PRUF:

121350345(RNF123)

ATRC:

139596027(RNF123)

GFR:	102041052(RNF123)

FAB:	101813051(RNF123)

OMA:	130258213(RNF123)

PHI:	102102071(RNF123)

PMAJ:

107210380(RNF123)

CCAE:

111935208(RNF123)

CCW:	104683198(RNF123)

CBRC:

103614242(RNF123)

ACOE:

138117300(RNF123)

ETL:	114058744(RNF123)

ZAB:	102061442(RNF123)

ZLE:	135453059(RNF123)

ACHL:

103798815(RNF123)

SVG:	106849251(RNF123)

MMEA:

130574696(RNF123)

HRT:	120758337(RNF123)

SATI:

136366129(RNF123)

CCIC:

134048670(RNF123)

FPG:	101916231(RNF123)

FCH:	102054985(RNF123)

CCRI:

104163526(RNF123)

NNT:	104408953(RNF123)

SHAB:

115614522(RNF123)

ACUN:

113484778(RNF123)

TALA:

104357391(RNF123)

ACHC:

115333238(RNF123)

HALD:

104315082(RNF123)

HLE:	104828097(RNF123)

AGEN:

126049690

HHAR:

128136744(RNF123)

GCL:

127021461

LDI:	104345393(RNF123)

MNB:	103775233(RNF123)

DPUB:

104306645(RNF123)

PPUS:

135182369(RNF123)

AVIT:

104270416(RNF123)

BRHI:

104491811(RNF123)

EGZ:	104132568(RNF123)

NNI:	104022963(RNF123)

PCRI:

104032165(RNF123)

PCAO:

104053416(RNF123)

PADL:

103922951(RNF123)

AFOR:

103900493(RNF123)

FGA:	104081887(RNF123)

CBOR:

142086349(RNF123)

GSTE:

104259655(RNF123)

CBOY:

140658265(RNF123)

MAME:

142415680(RNF123)

CLV:	102087958(RNF123)

CNIC:

135992890(RNF123)

MUI:	104539645(RNF123)

PLET:

104623621(RNF123)

EHS:	104506050(RNF123)

CMAC:

104473535(RNF123)

CUCA:

104059051(RNF123)

TEO:	104377915(RNF123)

BREG:

104629311(RNF123)

OHA:	104332236(RNF123)

ACAR:

104528300(RNF123)

CPEA:

104388096(RNF123)

CVF:	104283060(RNF123)

RTD:	128915630(RNF123)

CRID:

134521721(RNF123)

LMIC:

141749203(RNF123)

AAM:	106492172(RNF123)

AROW:

112960618(RNF123)

NPD:	112949137(RNF123)

TGT:	104577136(RNF123)

DNE:	112986991(RNF123)

SCAM:

104147842(RNF123)

ASN:	102376205(RNF123)

AMJ:	102576644(RNF123)

CPOO:

109318310(RNF123)

GGN:	109289194(RNF123)

CIZ:	142018984(RNF123)

CMY:	102942394(RNF123)

CCAY:

125639447(RNF123)

DCC:	119858244(RNF123)

CPIC:

101933630(RNF123)

TST:	117879813(RNF123)

CABI:

116816498(RNF123)

MRV:	120409292(RNF123)

ACS:	100560040(rnf123)

ASAO:

132769094(RNF123)

PVT:	110076990(RNF123)

SUND:

121922592(RNF123)

PBI:

103053241

PMUR:

107288690(RNF123)

CTIG:

120303994(RNF123)

TSR:	106541879(RNF123)

PGUT:

117679304(RNF123)

PCAE:

139312377(RNF123)

APRI:

131193004(RNF123)

PTEX:

113454465(RNF123)

NSS:	113415774(RNF123)

VKO:	123034259(RNF123)

PMUA:

114591494(RNF123)

PRAF:

128408115(RNF123)

ZVI:	118080548(RNF123)

HCG:	128345221(RNF123)

GJA:	107107160(RNF123)

STOW:

125430285(RNF123)

EMC:	129328825(RNF123)

XLA:	108714587(rnf123.L) 108715029(rnf123.S)

XTR:	100127191(rnf123)

NPR:	108803586(RNF123)

RTEM:

120944993(RNF123)

ACAT:

141102733(RNF123)

PADS:

140336879(RNF123)

BBUF:

120978970(RNF123)

BGAR:

122922656(RNF123)

DTC:	141069381(RNF123)

PWL:	138259259(RNF123)

MUO:	115471597(RNF123)

GSH:	117351339(RNF123)

DRE:	101884269(rnf123)

SRX:	107719710 107726274

SANH:

107661915 107703774(rnf123)

SGH:	107551355 107592836

CCAR:

CAUA:

CGIB:

PTET:

LROH:

GRF:

OMC:

PPRM:

RKG:

MAMB:

CIDE:

CERY:

MASI:

TROS:

TDW:

MANU:

129453404(rnf123)

PDAB:

135740908(rnf123)

IPU:

108254904

IFU:

128625228

PHYP:

113538129(rnf123)

SMEO:

TFD:

TVC:

CGAR:

NGRA:

TRN:

AMEX:

CMAO:

EEE:	113572382(rnf123)

CHAR:

105903027

SPIL:

134092031

ASAD:

121707433

TRU:	105419888(rnf123)

TFS:

130525016

TNG:	GSTEN00006135G001

LCO:	104937645(rnf123)

TBEN:

117482497

PGEO:

117440629(rnf123)

EMAC:

ELY:

EFO:

SLUC:

PFLV:

114554266(rnf123)

GAT:

PPUG:

AFB:

CLUM:

PSWI:

CANA:

CVE:

MSAM:

SCHU:

CUD:

SPUL:

ALAT:

ASTR:

MZE:	101465391(rnf123)

ONL:	100704567(rnf123)

OAU:

116322120

OLA:	101163564(rnf123)

OML:

112144882

CSAI:

133449533

XMA:	102219009(rnf123)

XCO:	114135156(rnf123)

XHE:	116710325(rnf123)

PRET:

103464247(rnf123)

PFOR:

103129722(rnf123)

PLAI:

106936948(rnf123)

PMEI:

106909283(rnf123)

GAF:

122834528

PPRL:

129355126 129356267

CVG:	107101544(rnf123) 107103902

CTUL:

119794296

GMU:

124856502

NFU:	107384847(rnf123)

KMR:

108228487

ALIM:

106511477(rnf123)

NWH:

AOCE:

EJA:

BFRE:

MCEP:

CSEM:

103386854(rnf123)

POV:	109644829(rnf123)

SSEN:

SSOE:

HHIP:

HSP:

PPLT:

SMAU:

LCF:

SDU:	111219497(rnf123)

SLAL:

111656515(rnf123)

XGL:

120807266

HCQ:	109522277(rnf123)

SSCV:

SBIA:

PEE:

PTAO:

BPEC:

110171132(rnf123)

ENY:	140365578(rnf123)

MALB:

109966927(rnf123)

BSPL:

114855172

SJO:

128355425

TTY:

137180858

GMH:	115557536(rnf123)

SASA:

106583775(rnf123)

STRU:

115149998(rnf123)

OTW:

112255369

OMY:

110529055

OGO:

124025296

ONE:	115131901(rnf123)

OKI:	109891460(rnf123)

OKE:

118399730

OMM:

135541322

OCLA:

139413907

SALP:

112070933(rnf123)

SNH:

120065512

SFON:

129815776

CCLU:

121578809

ELS:	105025489(rnf123)

OEP:

134019280

SFM:	108918421(rnf123)

PKI:	111843631(rnf123)

AANG:

118211011

AROT:

135237671

CCOG:

133110234

LOC:	102695723(rnf123)

PSPA:

121297967

ARUT:

117413968

PSEX:

120541440

LCM:	102357870(RNF123)

CMK:

103176755

CPLA:

122559128

CPUN:

140483925(rnf123)

HOC:

132822416

SCAU:

119973187

STOZ:

140388221(rnf123)

LERI:

129704606

HAKA:

140741964(rnf123)

PMRN:

116949270(RNF123)

LRJ:	133342504(RNF123)

BFO:

BBEL:

CIN:

SCLV:

SPU:

AFIL:

SKO:

PFLL:

DME:	Dmel_CG6752(Kpc1)

DER:

6552892

DSE:

6606317

DSI:	Dsimw501_GD20379(Dsim_GD20379)

DYA:	Dyak_GE26408

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI23662

DAZ:

108621320

DNV:

108649710

DHE:

111598632

DVI:	6629717(Kpc1)

CCAT:

BOD:

BDR:

RZE:

AOQ:

ALUD:

TDA:

MDE:

SCAC:

LCQ:

LSQ:

CVJ:	135949614(Kpc1)

GFS:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AMAP:

AFUN:

AMOU:

AMRS:

AALI:

ACOS:

AAG:

AALB:

ASUA:

CQU:	CpipJ_CPIJ012519

CPII:

CNS:

BCOO:

LLL:

PPAP:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BHUN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

ACOC:

MZT:

CCOA:

TCZ:

TSEP:

PBAR:

VEM:

COBS:

TLN:

HST:

DQU:

CFO:

FEX:

PMEC:

LHU:	105668623(Kpc1)

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

CTYP:

FAS:

DAM:

AGIF:

VCAN:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

BMOR:

MSEX:

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PXU:

BPHI:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

ONU:

ATRA:

GMW:

PXY:

CSTB:

CFUM:

API:

DNX:

RMD:

ACOO:

DVT:

BTAB:

DCI:

NLU:

LDA:

HVI:

MQU:

PHU:	Phum_PHUM177460

FOC:

TPAL:

ZNE:

CSEC:

PAME:

138712406(Kpc1)

BROR:

IEL:

HAMR:

FCD:

PVM:	113809315(Kpc1)

PJA:

PCHN:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

MNZ:

MRJ:

PORN:

HAZT:

OOT:

DSV:

DALB:

RSAN:

RMP:

VDE:

VJA:

GOE:

TUT:

CSCU:

CVS:

PTEP:

ABRU:

UDV:

SDM:

LGI:	LOTGIDRAFT_234381

PVUL:

PCAN:

LSAX:

BARL:

BGT:

GAE:

HRF:

HRJ:

HASI:

HCRA:

CRG:

CANU:

CVN:

OED:

MYI:

PMAX:

AIRR:

YBA:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

OSN:

LJP:

LAK:

LLON:

NVE:

EPA:	110244868 110253255

ATEN:

116298235 116304426

ADF:	107338925 107356059 107357631

AMIL:

MCAZ:

MFOO:

PDAM:

SPIS:

DGT:	114521872 114539304

XEN:

124433851

HMG:	100208776 100209144

HSY:

130625440

RES:

135692783

TAD:	TRIADDRAFT_58620

ATH:	AT2G22010(RKP)

ALY:

9314651

CRB:

17890505

CSAT:

104702746 104713649 104751849

EUS:	EUTSA_v10000015mg

BRP:

103842484

BNA:	106415060 106429081

BOE:

RSZ:

THJ:

CPAP:

CIT:

CIC:	CICLE_v10024728mg

PVY:

MINC:

TCC:

GRA:

GHI:	107914376 121208246

GAB:

HSYR:

DZI:

EGR:

RARG:

GMX:	100792381 100800617

GSJ:	114410149 114415715

PVU:

VRA:

VAR:

VUN:

VUM:

CCAJ:

APRC:

MTR:

TPRA:

CAM:

PSAT:

VVO:

LJA:

ADU:

AIP:

AHF:	112733252 112791231

LANG:

109326934 109361450

PCIN:

129307975

QSA:	O6P43_023273

FVE:	101300765 101308189

AANS:

RCN:

PPER:

PMUM:

PAVI:

PDUL:

MDM:	103405618 103454705

MSYL:

126605375 126620854

PXB:	103926685 103934790

PCOX:

ZJU:

MNT:

CSAV:

CSV:

CMO:

BHJ:

MCHA:

CMAX:

CMOS:

CPEP:

RCU:

MEAN:

JCU:

HBR:

MESC:

POP:	7457129 7486334

PEU:	105123865 105126439

PALZ:

118039286 118043506

PNZ:	133673386 133693586

JRE:

CILL:

CAVE:

AGLU:

QSU:

QLO:

CSAA:

TWL:

VVI:

VRI:

SLY:

SPEN:

SOT:

SSTN:

SDUL:

CANN:

LBB:

NTA:

NSY:

NTO:

NAU:

INI:

ITR:

SIND:

OEU:	111367633 111382685

EGT:

SSPL:

SMIL:

SHIS:

APAN:

HPUM:

PHUA:

PEBU:

PTAB:

HAN:	110885141 110903694

ECAD:

LSV:

CCAV:

DCR:

CSIN:

RVL:

AEW:

DLT:

BVG:

SOE:

CQI:	110703190 110724113

ATRI:

SLAF:

MOF:

NNU:

MING:

TSS:	122668009 122668959

PSOM:

OSA:

OBR:

OGL:

SBI:

ZMA:

MFLO:

SITA:

SVS:

PVIR:

PHAI:

PAUA:

TANG:

PDA:

EGU:

MUS:

ZOF:	121982236 121982237

DCT:

PEQ:

AOF:

MSIN:

ACAK:

NCOL:

ATR:

CJF:

SMO:	SELMODRAFT_149782 SELMODRAFT_161247

PPP:	112289691 112294415 112295279

CRE:	CHLRE_12g519150v5

CSL:	COCSUDRAFT_48964

MIS:	MICPUN_59463

MPP:	MICPUCDRAFT_57960

MBR:	MONBRDRAFT_29379

SRE:	PTSG_03239

EHI:	EHI_161890(321.t00009)

EDI:	EDI_060600

EIV:	EIN_198060

ACAN:

ACA1_366770

GTT:	GUITHDRAFT_115482

» show all

Reference

PMID:21229311

Authors

Zhao J, Zhang S, Wu X, Huan W, Liu Z, Wei H, Shen A, Teng H

Title

KPC1 expression and essential role after acute spinal cord injury in adult rat.

Journal

Neurochem Res 36:549-58 (2011)
DOI:10.1007/s11064-010-0377-y

Sequence

[rno:100190936]

Reference

PMID:15531880

Authors

Kamura T, Hara T, Matsumoto M, Ishida N, Okumura F, Hatakeyama S, Yoshida M, Nakayama K, Nakayama KI

Title

Cytoplasmic ubiquitin ligase KPC regulates proteolysis of p27(Kip1) at G1 phase.

Journal

Nat Cell Biol 6:1229-35 (2004)
DOI:10.1038/ncb1194

Sequence

[hsa:63891]

LinkDB

DBGET integrated database retrieval system