| Entry |
|
| Name |
Regulation of actin cytoskeleton - Mirounga leonina (Southern elephant seal) |
| Class |
Cellular Processes; Cell motility
|
| Pathway map |
| mlx04810 | Regulation of actin cytoskeleton |

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| Other DBs |
|
| Organism |
Mirounga leonina (Southern elephant seal) [GN: mlx]
|
| Gene |
| 117997778 | PPP1R12C; protein phosphatase 1 regulatory subunit 12C isoform X1 [KO:K17457] |
| 117998070 | ARHGEF1; rho guanine nucleotide exchange factor 1 isoform X1 [KO:K12330] |
| 117998664 | PDGFB; platelet-derived growth factor subunit B isoform X1 [KO:K17386] |
| 117998715 | RAC2; ras-related C3 botulinum toxin substrate 2 isoform X1 [KO:K07860] |
| 117999262 | PDGFA; platelet-derived growth factor subunit A isoform X1 [KO:K04359] |
| 117999301 | GNA12; guanine nucleotide-binding protein subunit alpha-12 [KO:K04346] |
| 117999338 | RAC1; ras-related C3 botulinum toxin substrate 1 isoform X1 [KO:K04392] |
| 117999604 | MYLPF; myosin regulatory light chain 2, skeletal muscle isoform [KO:K12758] |
| 117999804 | FGD1; FYVE, RhoGEF and PH domain-containing protein 1 [KO:K05720] |
| 118001589 | WASF1; wiskott-Aldrich syndrome protein family member 1 [KO:K05753] |
| 118004424 | PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153] |
| 118005796 | GNG14; putative guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-14 [KO:K04347] |
| 118006042 | PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta [KO:K02649] |
| 118006556 | PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153] |
| 118008531 | PPP1R12A; protein phosphatase 1 regulatory subunit 12A isoform X1 [KO:K06270] |
| 118009226 | ARHGEF7; rho guanine nucleotide exchange factor 7 isoform X1 [KO:K13710] |
| 118009576 | SPATA13; spermatogenesis-associated protein 13 isoform X1 [KO:K05769] |
| 118012587 | ARHGEF4; LOW QUALITY PROTEIN: rho guanine nucleotide exchange factor 4 [KO:K05769] |
| 118013325 | ARHGEF12; rho guanine nucleotide exchange factor 12 isoform X1 [KO:K07532] |
| 118013389 | ARHGEF6; rho guanine nucleotide exchange factor 6 isoform X1 [KO:K05729] |
| 118014193 | PPP1R12B; protein phosphatase 1 regulatory subunit 12B isoform X1 [KO:K12329] |
| 118016004 | CYFIP2; cytoplasmic FMR1-interacting protein 2 isoform X1 [KO:K05749] |
| 118016863 | PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649] |
| 118016912 | IQGAP2; ras GTPase-activating-like protein IQGAP2 isoform X1 [KO:K05767] |
| 118017539 | VAV2; guanine nucleotide exchange factor VAV2 isoform X1 [KO:K05730] |
| 118017688 | ARPC5L; actin-related protein 2/3 complex subunit 5-like protein [KO:K05754] |
| 118018453 | ARPC3; actin-related protein 2/3 complex subunit 3 isoform X1 [KO:K05756] |
| 118018471 | MYL2; myosin regulatory light chain 2, ventricular/cardiac muscle isoform isoform X1 [KO:K10351] |
| 118018814 | TIAM1; LOW QUALITY PROTEIN: T-lymphoma invasion and metastasis-inducing protein 1 [KO:K05731] |
| 118019289 | GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 [KO:K04347] |
| 118019468 | PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma [KO:K02649] |
| 118019818 | WASF2; wiskott-Aldrich syndrome protein family member 2 [KO:K05748] |
| 118019913 | CDC42; cell division control protein 42 homolog isoform X1 [KO:K04393] |
| 118020028 | PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1 [KO:K00922] [EC:2.7.1.153] |
| 118022565 | FGF2; LOW QUALITY PROTEIN: fibroblast growth factor 2 [KO:K18497] |
| 118022944 | CYFIP1; cytoplasmic FMR1-interacting protein 1 isoform X1 [KO:K05749] |
| 118023079 | IQGAP1; ras GTPase-activating-like protein IQGAP1 isoform X1 [KO:K16848] |
| 118023562 | BCAR1; breast cancer anti-estrogen resistance protein 1 isoform X1 [KO:K05726] |
| 118024184 | BAIAP2; brain-specific angiogenesis inhibitor 1-associated protein 2 isoform X1 [KO:K05627] |
| 118024340 | GNA13; guanine nucleotide-binding protein subunit alpha-13 [KO:K04639] |
| 118024428 | RAC3; ras-related C3 botulinum toxin substrate 3 isoform X1 [KO:K07861] |
| 118024560 | MYL7; myosin regulatory light chain 2, atrial isoform [KO:K12754] |
| 118026392 | FGD3; FYVE, RhoGEF and PH domain-containing protein 3 [KO:K05722] |
|
| Compound |
| C00681 | 1-Acyl-sn-glycerol 3-phosphate |
| C04637 | 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate |
| C05981 | Phosphatidylinositol-3,4,5-trisphosphate |
| C11554 | 1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate |
|
| Reference |
|
| Authors |
Burridge K, Wennerberg K. |
| Title |
Rho and Rac take center stage. |
| Journal |
|
| Reference |
|
| Authors |
Schmitz AA, Govek EE, Bottner B, Van Aelst L. |
| Title |
Rho GTPases: signaling, migration, and invasion. |
| Journal |
|
| Reference |
|
| Authors |
Takai Y, Sasaki T, Matozaki T. |
| Title |
Small GTP-binding proteins. |
| Journal |
|
| Reference |
|
| Authors |
Pollard TD. |
| Title |
The cytoskeleton, cellular motility and the reductionist agenda. |
| Journal |
|
| Reference |
|
| Authors |
Ridley AJ, Schwartz MA, Burridge K, Firtel RA, Ginsberg MH, Borisy G, Parsons JT, Horwitz AR. |
| Title |
Cell migration: integrating signals from front to back. |
| Journal |
|
| Reference |
|
| Authors |
Sastry SK, Burridge K. |
| Title |
Focal adhesions: a nexus for intracellular signaling and cytoskeletal dynamics. |
| Journal |
|
| Reference |
|
| Authors |
Fukata M, Nakagawa M, Kuroda S, Kaibuchi K. |
| Title |
Cell adhesion and Rho small GTPases. |
| Journal |
J Cell Sci 112 ( Pt 24):4491-500 (1999) |
Related pathway |
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| KO pathway |
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