KEGG   PATHWAY: mni05162
Entry
mni05162                    Pathway                                
Name
Measles - Macaca nemestrina (pig-tailed macaque)
Description
Measles virus (MV) is highly contagious virus that leads infant death worldwide. Humans are the unique natural reservoir for this virus. MV infection is characterized by virus-induced immune suppression that can lead to increased susceptibility to secondary bacterial and viral infections. The P, V and C proteins act as virulence factors to suppress innate immune response in host by inhibiting signaling for both type I IFN induction and JAK/STAT-mediated interferon-stimulated gene (ISG) induction. Moreover,  H protein expressed on viral particles and binding to SLAM or CD46,  as well as N protein liberated from infected cells and interacting with Fc-gamma R, causes an inhibition of IL-12 synthesis in dendritic cells. IL-12 is a key cytokine inducing cellular immune responses to protect host from the harm caused by pathogenic infections.
Class
Human Diseases; Infectious disease: viral
Pathway map
mni05162  Measles
mni05162

Organism
Macaca nemestrina (pig-tailed macaque) [GN:mni]
Gene
105484874  CD46; membrane cofactor protein isoform X1 [KO:K04007]
105476700  MSN; moesin isoform X1 [KO:K05763]
105498180  SLAMF1; signaling lymphocytic activation molecule isoform X1 [KO:K06536]
105484282  CD209 antigen [KO:K06563]
105484318  LOW QUALITY PROTEIN: CD209 antigen [KO:K06563]
105485638  DDX58; probable ATP-dependent RNA helicase DDX58 isoform X1 [KO:K12646] [EC:5.6.2.6]
105483341  IFIH1; interferon-induced helicase C domain-containing protein 1 [KO:K12647] [EC:5.6.2.6]
105481575  MAVS; mitochondrial antiviral-signaling protein isoform X1 [KO:K12648]
105467377  TRAF3; TNF receptor-associated factor 3 isoform X1 [KO:K03174]
105484842  IKBKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform X1 [KO:K07211] [EC:2.7.11.10]
105473459  TBK1; serine/threonine-protein kinase TBK1 [KO:K05410] [EC:2.7.11.10]
105497189  IRF3; interferon regulatory factor 3 isoform X1 [KO:K05411]
105478402  CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1 [KO:K04467] [EC:2.7.11.10]
105476527  IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1 [KO:K07209] [EC:2.7.11.10]
105471007  LOW QUALITY PROTEIN: NF-kappa-B essential modulator-like [KO:K07210]
105495392  NFKBIB; NF-kappa-B inhibitor beta isoform X1 [KO:K02581]
105477978  NFKBIA; NF-kappa-B inhibitor alpha [KO:K04734]
105486337  NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X3 [KO:K02580]
105469585  RELA; transcription factor p65 isoform X1 [KO:K04735]
105478130  TLR7; toll-like receptor 7 [KO:K05404]
105480535  toll-like receptor 9 isoform X1 [KO:K10161]
105480196  MYD88; myeloid differentiation primary response protein MyD88 [KO:K04729]
105467308  IRAK1; interleukin-1 receptor-associated kinase 1 [KO:K04730] [EC:2.7.11.1]
105470108  IRAK4; interleukin-1 receptor-associated kinase 4 isoform X1 [KO:K04733] [EC:2.7.11.1]
105494145  IRF7; interferon regulatory factor 7 isoform X1 [KO:K09447]
105465888  IFNA21; LOW QUALITY PROTEIN: interferon alpha-21 [KO:K05414]
105498418  interferon alpha-1/13-like [KO:K05414]
105498422  IFNA8; interferon alpha-8 [KO:K05414]
105498424  interferon alpha-6 [KO:K05414]
105498425  interferon alpha-1/13 [KO:K05414]
105498426  interferon alpha-2 [KO:K05414]
105498430  interferon alpha-4 [KO:K05414]
105465886  IFNB1; interferon beta [KO:K05415]
105463507  TLR2; toll-like receptor 2 [KO:K10159]
105487117  TLR4; toll-like receptor 4 precursor [KO:K10160]
105471571  TRAF6; TNF receptor-associated factor 6 [KO:K03175] [EC:2.3.2.27]
105496130  CSNK2A1; casein kinase II subunit alpha isoform X1 [KO:K03097] [EC:2.7.11.1]
105491514  CSNK2A2; casein kinase II subunit alpha' [KO:K03097] [EC:2.7.11.1]
105497628  CSNK2B; casein kinase II subunit beta isoform X1 [KO:K03115]
105465697  TNFAIP3; tumor necrosis factor alpha-induced protein 3 [KO:K11859] [EC:3.4.19.12]
105496641  MAP3K7; mitogen-activated protein kinase kinase kinase 7 isoform X1 [KO:K04427] [EC:2.7.11.25]
105489001  TAB2; TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 isoform X1 [KO:K04404]
105486663  MAPK8; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
105479668  MAPK10; mitogen-activated protein kinase 10 isoform X1 [KO:K04440] [EC:2.7.11.24]
105484084  MAPK9; mitogen-activated protein kinase 9 [KO:K04440] [EC:2.7.11.24]
105495146  JUN; transcription factor AP-1 [KO:K04448]
105495778  FOS; proto-oncogene c-Fos [KO:K04379]
105471785  IL1A; interleukin-1 alpha [KO:K04383]
105471787  IL1B; interleukin-1 beta [KO:K04519]
105475680  IL6; interleukin-6 isoform X1 [KO:K05405]
105488536  IL12A; interleukin-12 subunit alpha [KO:K05406]
105482347  IL12B; interleukin-12 subunit beta [KO:K05425]
105472707  IFNAR2; interferon alpha/beta receptor 2 isoform X1 [KO:K05131]
105483960  RACK1; receptor of activated protein C kinase 1 [KO:K14753]
105498461  JAK1; tyrosine-protein kinase JAK1 isoform X1 [KO:K11217] [EC:2.7.10.2]
105475871  TYK2; non-receptor tyrosine-protein kinase TYK2 isoform X1 [KO:K11219] [EC:2.7.10.2]
105468204  STAT1; signal transducer and activator of transcription 1-alpha/beta [KO:K11220]
105474140  STAT2; signal transducer and activator of transcription 2 [KO:K11221]
105477854  IRF9; interferon regulatory factor 9 [KO:K04693]
105493729  OAS3; LOW QUALITY PROTEIN: 2'-5'-oligoadenylate synthase 3 [KO:K14216] [EC:2.7.7.84]
105493381  OAS2; 2'-5'-oligoadenylate synthase 2 [KO:K14216] [EC:2.7.7.84]
105493382  OAS1; 2'-5'-oligoadenylate synthase 1 [KO:K14216] [EC:2.7.7.84]
105497976  ADAR; double-stranded RNA-specific adenosine deaminase isoform X1 [KO:K12968] [EC:3.5.4.37]
105472602  MX1; interferon-induced GTP-binding protein Mx1 [KO:K14754]
105472607  MX2; interferon-induced GTP-binding protein Mx2 [KO:K14754]
105498124  EIF2AK1; eukaryotic translation initiation factor 2-alpha kinase 1 [KO:K16194] [EC:2.7.11.1]
105464848  EIF2AK2; LOW QUALITY PROTEIN: interferon-induced, double-stranded RNA-activated protein kinase [KO:K16195] [EC:2.7.11.1]
105496025  EIF2AK3; eukaryotic translation initiation factor 2-alpha kinase 3 [KO:K08860] [EC:2.7.11.1]
105492461  EIF2AK4; eIF-2-alpha kinase GCN2 isoform X1 [KO:K16196] [EC:2.7.11.1]
105478142  RAB9A; ras-related protein Rab-9A [KO:K07899]
105499752  RAB9B; ras-related protein Rab-9B isoform X1 [KO:K07900]
105476325  HSPA8; heat shock cognate 71 kDa protein [KO:K03283]
105497606  HSPA1L; heat shock 70 kDa protein 1-like [KO:K03283]
105497607  heat shock 70 kDa protein 1 isoform X1 [KO:K03283]
105498221  HSPA6; LOW QUALITY PROTEIN: heat shock 70 kDa protein 6 [KO:K03283]
105498547  LOW QUALITY PROTEIN: heat shock cognate 71 kDa protein-like [KO:K03283]
105475946  EIF3H; eukaryotic translation initiation factor 3 subunit H isoform X1 [KO:K03247]
105472858  EIF2S1; eukaryotic translation initiation factor 2 subunit 1 [KO:K03237]
105477274  RCHY1; RING finger and CHY zinc finger domain-containing protein 1 isoform X1 [KO:K10144] [EC:2.3.2.27]
105473688  TP53; cellular tumor antigen p53 [KO:K04451]
105496668  TP73; tumor protein p73 isoform X1 [KO:K10148]
105478601  BBC3; bcl-2-binding component 3 [KO:K10132]
105484428  FASLG; tumor necrosis factor ligand superfamily member 6 [KO:K04389]
105480710  FAS; tumor necrosis factor receptor superfamily member 6 precursor [KO:K04390]
105491441  TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein isoform X2 [KO:K03171]
105469733  FADD; FAS-associated death domain protein [KO:K02373]
105468105  CASP8; caspase-8 isoform X1 [KO:K04398] [EC:3.4.22.61]
105480751  BH3-interacting domain death agonist [KO:K04726]
105478665  BAX; apoptosis regulator BAX isoform X1 [KO:K02159]
105474465  BAK1; bcl-2 homologous antagonist/killer isoform X1 [KO:K14021]
105477002  BCL2; apoptosis regulator Bcl-2 [KO:K02161]
105496162  BCL2L1; bcl-2-like protein 1 isoform X1 [KO:K04570]
105469512  BAD; bcl2-associated agonist of cell death [KO:K02158]
105475711  cytochrome c [KO:K08738]
105495842  cytochrome c-like [KO:K08738]
105477037  cytochrome c-like [KO:K08738]
105486922  cytochrome c-like [KO:K08738]
105477715  cytochrome c-like [KO:K08738]
105487609  cytochrome c-like [KO:K08738]
105497820  cytochrome c-like [KO:K08738]
105491771  cytochrome c-like [KO:K08738]
112428088  cytochrome c-like [KO:K08738]
105485043  cytochrome c-like [KO:K08738]
105495023  cytochrome c-like [KO:K08738]
105463369  APAF1; apoptotic protease-activating factor 1 isoform X1 [KO:K02084]
105473212  CASP9; caspase-9 [KO:K04399] [EC:3.4.22.62]
105466747  CASP3; LOW QUALITY PROTEIN: caspase-3 [KO:K02187] [EC:3.4.22.56]
105492342  caspase-3-like isoform X1 [KO:K02187] [EC:3.4.22.56]
105482108  CDKN1B; cyclin-dependent kinase inhibitor 1B isoform X1 [KO:K06624]
105469727  CCND1; G1/S-specific cyclin-D1 [KO:K04503]
105484147  CCND2; G1/S-specific cyclin-D2 [KO:K10151]
105489611  CCND3; G1/S-specific cyclin-D3 isoform X1 [KO:K10152]
105497230  CCNE2; G1/S-specific cyclin-E2 isoform X1 [KO:K06626]
105487658  CCNE1; G1/S-specific cyclin-E1 isoform X1 [KO:K06626]
105474081  CDK4; cyclin-dependent kinase 4 [KO:K02089] [EC:2.7.11.22]
105475503  CDK6; cyclin-dependent kinase 6 isoform X1 [KO:K02091] [EC:2.7.11.22]
105474169  CDK2; cyclin-dependent kinase 2 isoform X1 [KO:K02206] [EC:2.7.11.22]
105471202  LOW QUALITY PROTEIN: uncharacterized protein LOC105471202 [KO:K10785]
105476413  CD3D; T-cell surface glycoprotein CD3 delta chain isoform X1 [KO:K06450]
105476414  CD3E; T-cell surface glycoprotein CD3 epsilon chain [KO:K06451]
105476412  CD3G; T-cell surface glycoprotein CD3 gamma chain isoform X1 [KO:K06452]
105468057  CD28; CD28 molecule precursor [KO:K06470]
105486135  IL2; interleukin-2 precursor [KO:K05429]
105494366  IL2RA; interleukin-2 receptor subunit alpha isoform X1 [KO:K05068]
105464497  IL2RB; interleukin-2 receptor subunit beta isoform X2 [KO:K05069]
105476651  IL2RG; cytokine receptor common subunit gamma [KO:K05070]
105475205  PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
105488082  PIK3R2; LOW QUALITY PROTEIN: phosphatidylinositol 3-kinase regulatory subunit beta [KO:K02649]
105494953  PIK3R3; LOW QUALITY PROTEIN: phosphatidylinositol 3-kinase regulatory subunit gamma [KO:K02649]
105478978  PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
105489973  PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
105469947  PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
105477589  CBLB; E3 ubiquitin-protein ligase CBL-B [KO:K22517] [EC:2.3.2.27]
105474669  AKT3; RAC-gamma serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
105489842  AKT1; RAC-alpha serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
105495343  AKT2; RAC-beta serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
105470323  GSK3B; glycogen synthase kinase-3 beta isoform X1 [KO:K03083] [EC:2.7.11.26]
105486722  JAK3; tyrosine-protein kinase JAK3 [KO:K11218] [EC:2.7.10.2]
105472413  STAT3; signal transducer and activator of transcription 3 [KO:K04692]
105472122  signal transducer and activator of transcription 5A [KO:K11223]
105472124  LOW QUALITY PROTEIN: signal transducer and activator of transcription 5B [KO:K11224]
105498217  FCGR2B; low affinity immunoglobulin gamma Fc region receptor II-b isoform X1 [KO:K12560]
Compound
C05981  Phosphatidylinositol-3,4,5-trisphosphate
Reference
PMID:19203113
  Authors
Schneider-Schaulies S, Schneider-Schaulies J
  Title
Measles virus-induced immunosuppression.
  Journal
Curr Top Microbiol Immunol 330:243-69 (2009)
DOI:10.1007/978-3-540-70617-5_12
Reference
PMID:19203114
  Authors
Hahm B
  Title
Hostile communication of measles virus with host innate immunity and dendritic cells.
  Journal
Curr Top Microbiol Immunol 330:271-87 (2009)
DOI:10.1007/978-3-540-70617-5_13
Reference
PMID:19198566
  Authors
Gerlier D, Valentin H
  Title
Measles virus interaction with host cells and impact on innate immunity.
  Journal
Curr Top Microbiol Immunol 329:163-91 (2009)
DOI:10.1007/978-3-540-70523-9_8
Reference
PMID:16690907
  Authors
Schneider-Schaulies S, Dittmer U
  Title
Silencing T cells or T-cell silencing: concepts in virus-induced immunosuppression.
  Journal
J Gen Virol 87:1423-38 (2006)
DOI:10.1099/vir.0.81713-0
Reference
PMID:22049305
  Authors
Avota E, Gassert E, Schneider-Schaulies S
  Title
Cytoskeletal dynamics: concepts in measles virus replication and immunomodulation.
  Journal
Viruses 3:102-17 (2011)
DOI:10.3390/v3020102
Reference
PMID:27854326
  Authors
Jiang Y, Qin Y, Chen M
  Title
Host-Pathogen Interactions in Measles Virus Replication and Anti-Viral Immunity.
  Journal
Viruses 8:E308 (2016)
DOI:10.3390/v8110308
Reference
PMID:18922877
  Authors
Pfaller CK, Conzelmann KK
  Title
Measles virus V protein is a decoy substrate for IkappaB kinase alpha and prevents Toll-like receptor 7/9-mediated interferon induction.
  Journal
J Virol 82:12365-73 (2008)
DOI:10.1128/JVI.01321-08
Reference
PMID:17720800
  Authors
Yokota S, Okabayashi T, Yokosawa N, Fujii N
  Title
Measles virus P protein suppresses Toll-like receptor signal through up-regulation of ubiquitin-modifying enzyme A20.
  Journal
FASEB J 22:74-83 (2008)
DOI:10.1096/fj.07-8976com
Reference
PMID:23146309
  Authors
Delpeut S, Noyce RS, Siu RW, Richardson CD
  Title
Host factors and measles virus replication.
  Journal
Curr Opin Virol 2:773-83 (2012)
DOI:10.1016/j.coviro.2012.10.008
Reference
PMID:26878224
  Authors
Shah M, Anwar MA, Kim JH, Choi S
  Title
Advances in Antiviral Therapies Targeting Toll-like Receptors.
  Journal
Expert Opin Investig Drugs 25:437-53 (2016)
DOI:10.1517/13543784.2016.1154040
Reference
PMID:12620806
  Authors
Yokota S, Saito H, Kubota T, Yokosawa N, Amano K, Fujii N
  Title
Measles virus suppresses interferon-alpha signaling pathway: suppression of Jak1 phosphorylation and association of viral accessory proteins, C and V, with interferon-alpha receptor complex.
  Journal
Virology 306:135-46 (2003)
DOI:10.1016/S0042-6822(02)00026-0
Reference
PMID:12804771
  Authors
Takeuchi K, Kadota SI, Takeda M, Miyajima N, Nagata K
  Title
Measles virus V protein blocks interferon (IFN)-alpha/beta but not IFN-gamma signaling by inhibiting STAT1 and STAT2 phosphorylation.
  Journal
FEBS Lett 545:177-82 (2003)
DOI:10.1016/S0014-5793(03)00528-3
Reference
PMID:12805463
  Authors
Palosaari H, Parisien JP, Rodriguez JJ, Ulane CM, Horvath CM
  Title
STAT protein interference and suppression of cytokine signal transduction by measles virus V protein.
  Journal
J Virol 77:7635-44 (2003)
DOI:10.1128/JVI.77.13.7635-7644.2003
Reference
PMID:14585342
  Authors
Shaffer JA, Bellini WJ, Rota PA
  Title
The C protein of measles virus inhibits the type I interferon response.
  Journal
Virology 315:389-97 (2003)
DOI:10.1016/S0042-6822(03)00537-3
Reference
PMID:16971451
  Authors
Carsillo T, Traylor Z, Choi C, Niewiesk S, Oglesbee M
  Title
hsp72, a host determinant of measles virus neurovirulence.
  Journal
J Virol 80:11031-9 (2006)
DOI:10.1128/JVI.01438-06
Reference
PMID:15914229
  Authors
Zhang X, Bourhis JM, Longhi S, Carsillo T, Buccellato M, Morin B, Canard B, Oglesbee M
  Title
Hsp72 recognizes a P binding motif in the measles virus N protein C-terminus.
  Journal
Virology 337:162-74 (2005)
DOI:10.1016/j.virol.2005.03.035
Reference
PMID:29712906
  Authors
Ke Z, Strauss JD, Hampton CM, Brindley MA, Dillard RS, Leon F, Lamb KM, Plemper RK, Wright ER
  Title
Promotion of virus assembly and organization by the measles virus matrix protein.
  Journal
Nat Commun 9:1736 (2018)
DOI:10.1038/s41467-018-04058-2
Reference
PMID:24155404
  Authors
Pfaller CK, Radeke MJ, Cattaneo R, Samuel CE
  Title
Measles virus C protein impairs production of defective copyback double-stranded viral RNA and activation of protein kinase R.
  Journal
J Virol 88:456-68 (2014)
DOI:10.1128/JVI.02572-13
Reference
PMID:17686838
  Authors
Sato H, Masuda M, Kanai M, Tsukiyama-Kohara K, Yoneda M, Kai C
  Title
Measles virus N protein inhibits host translation by binding to eIF3-p40.
  Journal
J Virol 81:11569-76 (2007)
DOI:10.1128/JVI.00570-07
Reference
PMID:19895323
  Authors
Sion-Vardy N, Lasarov I, Delgado B, Gopas J, Benharroch D, Ariad S
  Title
Measles virus: evidence for association with lung cancer.
  Journal
Exp Lung Res 35:701-12 (2009)
DOI:10.3109/01902140902853176
Reference
PMID:16140759
  Authors
Chen M, Cortay JC, Logan IR, Sapountzi V, Robson CN, Gerlier D
  Title
Inhibition of ubiquitination and stabilization of human ubiquitin E3 ligase PIRH2 by measles virus phosphoprotein.
  Journal
J Virol 79:11824-36 (2005)
DOI:10.1128/JVI.79.18.11824-11836.2005
Reference
PMID:16699046
  Authors
Cruz CD, Palosaari H, Parisien JP, Devaux P, Cattaneo R, Ouchi T, Horvath CM
  Title
Measles virus V protein inhibits p53 family member p73.
  Journal
J Virol 80:5644-50 (2006)
DOI:10.1128/JVI.02400-05
Reference
PMID:10756053
  Authors
Servet-Delprat C, Vidalain PO, Azocar O, Le Deist F, Fischer A, Rabourdin-Combe C
  Title
Consequences of Fas-mediated human dendritic cell apoptosis induced by measles virus.
  Journal
J Virol 74:4387-93 (2000)
DOI:10.1128/JVI.74.9.4387-4393.2000
Reference
PMID:20601611
  Authors
Kushwah R, Hu J
  Title
Dendritic cell apoptosis: regulation of tolerance versus immunity.
  Journal
J Immunol 185:795-802 (2010)
DOI:10.4049/jimmunol.1000325
Reference
PMID:10590149
  Authors
Vidalain PO, Azocar O, Lamouille B, Astier A, Rabourdin-Combe C, Servet-Delprat C
  Title
Measles virus induces functional TRAIL production by human dendritic cells.
  Journal
J Virol 74:556-9 (2000)
DOI:10.1128/JVI.74.1.556-559.2000
Reference
PMID:11846228
  Authors
Vidalain PO, Azocar O, Rabourdin-Combe C, Servet-Delprat C
  Title
Measle virus-infected dendritic cells develop immunosuppressive and cytotoxic activities.
  Journal
Immunobiology 204:629-38 (2001)
DOI:10.1078/0171-2985-00102
Reference
PMID:10423127
  Authors
Engelking O, Fedorov LM, Lilischkis R, ter Meulen V, Schneider-Schaulies S
  Title
Measles virus-induced immunosuppression in vitro is associated with deregulation of G1 cell cycle control proteins.
  Journal
J Gen Virol 80 ( Pt 7):1599-608 (1999)
DOI:10.1099/0022-1317-80-7-1599
Reference
PMID:30510918
  Authors
Fan Y, Sanyal S, Bruzzone R
  Title
Breaking Bad: How Viruses Subvert the Cell Cycle.
  Journal
Front Cell Infect Microbiol 8:396 (2018)
DOI:10.3389/fcimb.2018.00396
Reference
PMID:20636817
  Authors
Griffin DE
  Title
Measles virus-induced suppression of immune responses.
  Journal
Immunol Rev 236:176-89 (2010)
DOI:10.1111/j.1600-065X.2010.00925.x
Reference
PMID:11385511
  Authors
Avota E, Avots A, Niewiesk S, Kane LP, Bommhardt U, ter Meulen V, Schneider-Schaulies S
  Title
Disruption of Akt kinase activation is important for immunosuppression induced by measles virus.
  Journal
Nat Med 7:725-31 (2001)
DOI:10.1038/89106
Reference
PMID:15308747
  Authors
Avota E, Muller N, Klett M, Schneider-Schaulies S
  Title
Measles virus interacts with and alters signal transduction in T-cell lipid rafts.
  Journal
J Virol 78:9552-9 (2004)
DOI:10.1128/JVI.78.17.9552-9559.2004
Reference
PMID:16963735
  Authors
Yanagi Y, Takeda M, Ohno S
  Title
Measles virus: cellular receptors, tropism and pathogenesis.
  Journal
J Gen Virol 87:2767-79 (2006)
DOI:10.1099/vir.0.82221-0
Reference
PMID:16237742
  Authors
Kerdiles YM, Sellin CI, Druelle J, Horvat B
  Title
Immunosuppression caused by measles virus: role of viral proteins.
  Journal
Rev Med Virol 16:49-63 (2006)
DOI:10.1002/rmv.486
Related
pathway
mni04110  Cell cycle
mni04115  p53 signaling pathway
mni04120  Ubiquitin mediated proteolysis
mni04210  Apoptosis
mni04620  Toll-like receptor signaling pathway
mni04622  RIG-I-like receptor signaling pathway
mni04630  JAK-STAT signaling pathway
mni04658  Th1 and Th2 cell differentiation
mni04660  T cell receptor signaling pathway
KO pathway
ko05162   
LinkDB

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