KEGG   PATHWAY: shr04060
Entry
shr04060                    Pathway                                
Name
Cytokine-cytokine receptor interaction - Sarcophilus harrisii (Tasmanian devil)
Description
Cytokines are soluble extracellular proteins or glycoproteins that are crucial intercellular regulators and mobilizers of cells engaged in innate as well as adaptive inflammatory host defenses, cell growth, differentiation, cell death, angiogenesis, and development and repair processes aimed at the restoration of homeostasis. Cytokines are released by various cells in the body, usually in response to an activating stimulus, and they induce responses through binding to specific receptors on the cell surface of target cells. Cytokines can be grouped by structure into different families and their receptors can likewise be grouped.
Class
Environmental Information Processing; Signaling molecules and interaction
Pathway map
shr04060  Cytokine-cytokine receptor interaction
shr04060

Organism
Sarcophilus harrisii (Tasmanian devil) [GN:shr]
Gene
100913243  IL22RA1; interleukin-22 receptor subunit alpha-1 [KO:K05138]
100913252  IL1R2; interleukin-1 receptor type 2 isoform X1 [KO:K04387]
100913275  IL2RB; interleukin-2 receptor subunit beta [KO:K05069]
100913307  IL6ST; interleukin-6 receptor subunit beta isoform X1 [KO:K05060]
100913351  [KO:K04180]
100913352  TGFBR2; TGF-beta receptor type-2 [KO:K04388] [EC:2.7.11.30]
100913438  ACVRL1; serine/threonine-protein kinase receptor R3 isoform X1 [KO:K13594] [EC:2.7.11.30]
100913471  IL34; interleukin-34 isoform X1 [KO:K22633]
100913486  CCL21; C-C motif chemokine 21 [KO:K16062]
100913505  IFNLR1; interferon lambda receptor 1 [KO:K05140]
100913514  [KO:K04386]
100913616  [KO:K04180]
100913702  ACVR1B; activin receptor type-1B isoform X1 [KO:K13567] [EC:2.7.11.30]
100913777  IL1RL2; interleukin-1 receptor-like 2 isoform X1 [KO:K05172]
100913844  TGFBR1; TGF-beta receptor type-1 isoform X1 [KO:K04674] [EC:2.7.11.30]
100914043  IL1RL1; interleukin-1 receptor-like 1 [KO:K05171]
100914129  LEPR; leptin receptor isoform X2 [KO:K05062]
100914201  IL12A; interleukin-12 subunit alpha [KO:K05406]
100914254  BMP7; bone morphogenetic protein 7 [KO:K16621]
100914298  IL18R1; interleukin-18 receptor 1 isoform X1 [KO:K05173]
100914299  [KO:K22669]
100914334  CLCF1; cardiotrophin-like cytokine factor 1 [KO:K05421]
100914374  TNFRSF1B; tumor necrosis factor receptor superfamily member 1B isoform X1 [KO:K05141]
100914443  [KO:K05415]
100914565  [KO:K22669]
100914610  TNFRSF6B; tumor necrosis factor receptor superfamily member 6B [KO:K05143]
100914627  TNFRSF12A; tumor necrosis factor receptor superfamily member 12A [KO:K05149]
100914681  IL4; interleukin-4 [KO:K05430]
100914694  TNFRSF11A; LOW QUALITY PROTEIN: tumor necrosis factor receptor superfamily member 11A [KO:K05147]
100914703  [KO:K05414]
100914748  ACKR4; atypical chemokine receptor 4 [KO:K04186]
100914910  TGFB2; transforming growth factor beta-2 proprotein [KO:K13376]
100914965  [KO:K05414]
100914986  [KO:K05507]
100915124  RELL2; RELT-like protein 2 isoform X1 [KO:K26541]
100915178  IL26; interleukin-26 [KO:K05446]
100915440  [KO:K05505]
100915478  IL7R; interleukin-7 receptor subunit alpha isoform X1 [KO:K05072]
100915784  [KO:K12964]
100915999  PRLR; prolactin receptor [KO:K05081]
100916021  [KO:K16622]
100916024  CCL20; C-C motif chemokine 20 isoform X1 [KO:K14625]
100916471  TNFSF13; tumor necrosis factor ligand superfamily member 13 [KO:K05475]
100916478  [KO:K12964]
100916578  XCR1; chemokine XC receptor 1 [KO:K04193]
100916609  BMP4; bone morphogenetic protein 4 [KO:K04662]
100916709  IL5RA; interleukin-5 receptor subunit alpha isoform X1 [KO:K05067]
100916737  [KO:K12964]
100916836  [KO:K04178]
100916950  CSF1R; macrophage colony-stimulating factor 1 receptor [KO:K05090] [EC:2.7.10.1]
100917003  [KO:K12964]
100917236  TNFSF9; tumor necrosis factor ligand superfamily member 9 [KO:K05472]
100917263  [KO:K12964]
100917626  IL16; pro-interleukin-16 isoform X2 [KO:K22628]
100917661  IL27; interleukin-27 subunit alpha [KO:K22629]
100917694  CCR10; C-C chemokine receptor type 10 [KO:K04185]
100917781  [KO:K12964]
100917948  IL3RA; interleukin-3 receptor subunit alpha isoform X1 [KO:K04737]
100917955  IL10; LOW QUALITY PROTEIN: interleukin-10 [KO:K05443]
100918041  [KO:K05408]
100918070  CD40LG; CD40 ligand [KO:K03161]
100918216  IL19; interleukin-19 [KO:K05444]
100918228  [KO:K04176]
100918439  EBI3; interleukin-27 subunit beta [KO:K24476]
100918476  IL20; interleukin-20 [KO:K22667]
100918537  ACVR2A; activin receptor type-2A isoform X1 [KO:K04670] [EC:2.7.11.30]
100918574  CXCL12; stromal cell-derived factor 1 isoform X2 [KO:K10031]
100918625  IL17D; interleukin-17D [KO:K05492]
100918670  CNTF; ciliary neurotrophic factor [KO:K05420]
100918737  IL24; interleukin-24 [KO:K22668]
100918755  NODAL; nodal homolog [KO:K04666]
100918871  CD70; CD70 antigen [KO:K05470]
100918907  [KO:K14624]
100918968  IL17RB; LOW QUALITY PROTEIN: interleukin-17 receptor B [KO:K05165]
100919001  IL20RA; interleukin-20 receptor subunit alpha [KO:K05136]
100919064  IFNAR1; LOW QUALITY PROTEIN: interferon alpha/beta receptor 1 [KO:K05130]
100919171  [KO:K05408]
100919327  IL10RB; interleukin-10 receptor subunit beta [KO:K05135]
100919342  ACKR3; atypical chemokine receptor 3 [KO:K04304]
100919390  AMH; muellerian-inhibiting factor [KO:K04665]
100919776  FASLG; tumor necrosis factor ligand superfamily member 6 isoform X1 [KO:K04389]
100919788  TNFRSF1A; tumor necrosis factor receptor superfamily member 1A [KO:K03158]
100919934  [KO:K05482]
100919996  IL1F10; interleukin-1 family member 10 [KO:K05488]
100920316  LTBR; tumor necrosis factor receptor superfamily member 3 [KO:K03159]
100920492  BMPR1B; bone morphogenetic protein receptor type-1B isoform X1 [KO:K13578] [EC:2.7.11.30]
100920573  CD27; CD27 antigen [KO:K05144]
100920716  IL18; interleukin-18 [KO:K05482]
100920794  IL21R; interleukin-21 receptor isoform X3 [KO:K05075]
100920968  [KO:K05414]
100921316  CCL19; C-C motif chemokine 19 [KO:K05512]
100921354  TNFRSF21; tumor necrosis factor receptor superfamily member 21 isoform X1 [KO:K05157]
100921581  [KO:K16598]
100921616  LTA; lymphotoxin-alpha [KO:K05468]
100921741  CCL22; C-C motif chemokine 22 [KO:K21095]
100921841  GALT; galactose-1-phosphate uridylyltransferase isoform X1 [KO:K05056]
100921875  TNF; tumor necrosis factor [KO:K03156]
100921946  [KO:K04175]
100922003  CX3CL1; fractalkine [KO:K05508]
100922104  IL4R; interleukin-4 receptor subunit alpha isoform X1 [KO:K05071]
100922136  LTB; lymphotoxin-beta isoform X1 [KO:K03157]
100922206  [KO:K05050]
100922240  CXCL10; C-X-C motif chemokine 10 [KO:K12671]
100922264  CCL17; LOW QUALITY PROTEIN: C-C motif chemokine 17 [KO:K21083]
100922350  IL1B; interleukin-1 beta [KO:K04519]
100922441  EPOR; erythropoietin receptor isoform X1 [KO:K05079]
100922547  INHBB; inhibin beta B chain [KO:K22687]
100922616  IL27RA; interleukin-27 receptor subunit alpha [KO:K19598]
100922868  [KO:K05487]
100922992  [KO:K05438]
100923143  CNTFR; ciliary neurotrophic factor receptor subunit alpha [KO:K05059]
100923154  TNFRSF19; tumor necrosis factor receptor superfamily member 19 [KO:K05155]
100923185  CD4; T-cell surface glycoprotein CD4 precursor [KO:K06454]
100923207  IL13RA2; interleukin-13 receptor subunit alpha-2 isoform X2 [KO:K05077]
100923393  IL36RN; LOW QUALITY PROTEIN: interleukin-36 receptor antagonist protein [KO:K05483]
100923594  RELT; tumor necrosis factor receptor superfamily member 19L [KO:K05156]
100923652  [KO:K05481]
100923822  CXCL14; C-X-C motif chemokine 14 [KO:K10033]
100924125  TNFRSF25; tumor necrosis factor receptor superfamily member 25 [KO:K05160]
100924161  RELL1; RELT-like protein 1 [KO:K26541]
100924490  EPO; erythropoietin [KO:K05437]
100924612  BMP10; bone morphogenetic protein 10 [KO:K22670]
100924664  IL6R; interleukin-6 receptor subunit alpha [KO:K05055]
100924883  INHBA; inhibin beta A chain [KO:K04667]
100925102  [KO:K12964]
100925305  TNFSF8; tumor necrosis factor ligand superfamily member 8 [KO:K05471]
100925445  CSF3; LOW QUALITY PROTEIN: granulocyte colony-stimulating factor [KO:K05423]
100925684  IL20RB; interleukin-20 receptor subunit beta [KO:K05137]
100925781  BMPR2; bone morphogenetic protein receptor type-2 isoform X1 [KO:K04671] [EC:2.7.11.30]
100926242  CCR4; C-C chemokine receptor type 4 isoform X1 [KO:K04179]
100926362  CCL28; C-C motif chemokine 28 [KO:K05513]
100926390  TNFSF13B; tumor necrosis factor ligand superfamily member 13B [KO:K05476]
100926419  GDF11; growth/differentiation factor 11 [KO:K22679]
100926507  CX3CR1; CX3C chemokine receptor 1 [KO:K04192]
100926512  IL15; interleukin-15 isoform X1 [KO:K05433]
100926770  CCR8; C-C chemokine receptor type 8 [KO:K04183]
100926905  IL10RA; interleukin-10 receptor subunit alpha isoform X1 [KO:K05134]
100927086  NGFR; tumor necrosis factor receptor superfamily member 16 [KO:K02583]
100927255  TNFRSF9; tumor necrosis factor receptor superfamily member 9 [KO:K05146]
100927655  GHR; growth hormone receptor isoform X1 [KO:K05080]
100927876  IL17RA; interleukin-17 receptor A [KO:K05164]
100928279  ACVR1; activin receptor type-1 [KO:K04675] [EC:2.7.11.30]
100928319  BMPR1A; bone morphogenetic protein receptor type-1A [KO:K04673] [EC:2.7.11.30]
100928499  CXCR3; C-X-C chemokine receptor type 3 [KO:K04188]
100928707  CSF3R; granulocyte colony-stimulating factor receptor [KO:K05061]
100928781  [KO:K05422]
100928822  IL17A; interleukin-17A [KO:K05489]
100929077  IL17F; interleukin-17F [KO:K05494]
100929544  BMP6; bone morphogenetic protein 6 [KO:K16620]
100929576  IFNGR2; interferon gamma receptor 2 [KO:K05133]
100929617  TGFB3; transforming growth factor beta-3 proprotein [KO:K13377]
100929623  IL17B; interleukin-17B [KO:K05490]
100929763  AMHR2; anti-Muellerian hormone type-2 receptor [KO:K04672] [EC:2.7.11.30]
100929781  IL2RG; cytokine receptor common subunit gamma isoform X2 [KO:K05070]
100929797  GDF6; growth/differentiation factor 6 [KO:K20012]
100929823  IL18RAP; interleukin-18 receptor accessory protein [KO:K05174]
100930117  INHBC; inhibin beta C chain [KO:K22688]
100930199  LEP; leptin [KO:K05424]
100930278  CSF1; macrophage colony-stimulating factor 1 isoform X2 [KO:K05453]
100930279  NGF; beta-nerve growth factor [KO:K02582]
100930374  INHBE; inhibin beta E chain [KO:K22689]
100930500  IL17RE; interleukin-17 receptor E isoform X1 [KO:K05168]
100930564  GDF5; growth/differentiation factor 5 [KO:K04664]
100930670  GDF10; growth/differentiation factor 10 [KO:K22674]
100930764  IL17RC; interleukin-17 receptor C isoform X1 [KO:K05166]
100930811  BMP3; bone morphogenetic protein 3 [KO:K05496]
100930891  IL23R; interleukin-23 receptor [KO:K05065]
100930920  IL13RA1; interleukin-13 receptor subunit alpha-1 [KO:K05076]
100931037  ACVR1C; activin receptor type-1C isoform X2 [KO:K13568] [EC:2.7.11.30]
100931043  INHA; LOW QUALITY PROTEIN: inhibin alpha chain [KO:K05500]
100931154  IL12RB2; interleukin-12 receptor subunit beta-2 [KO:K05064]
100931461  TNFRSF11B; tumor necrosis factor receptor superfamily member 11B [KO:K05148]
100931911  [KO:K02583]
100932026  BMP5; bone morphogenetic protein 5 [KO:K04663]
100932090  MSTN; growth/differentiation factor 8 [KO:K05497]
100932234  IL17C; interleukin-17C [KO:K05491]
100932342  TNFSF14; tumor necrosis factor ligand superfamily member 14 isoform X1 [KO:K05477]
100932486  IL12B; interleukin-12 subunit beta [KO:K05425]
100932607  TGFB1; LOW QUALITY PROTEIN: transforming growth factor beta-1 proprotein [KO:K13375]
100932842  PRL; prolactin [KO:K05439]
100932896  GDF3; growth/differentiation factor 3 [KO:K22672]
100933140  IL1RAP; interleukin-1 receptor accessory protein isoform X1 [KO:K04723]
100933153  CCR6; C-C chemokine receptor type 6 [KO:K04181]
100933427  IL23A; interleukin-23 subunit alpha [KO:K05426]
100933600  CXCL8; interleukin-8 [KO:K10030]
100933894  ACVR2B; activin receptor type-2B [KO:K13596] [EC:2.7.11.30]
100934043  IL5; interleukin-5 [KO:K05428]
100934273  [KO:K21096]
100934302  EDA; ectodysplasin-A [KO:K05480]
100934321  OSMR; oncostatin-M-specific receptor subunit beta [KO:K05057]
100934326  LIF; leukemia inhibitory factor [KO:K05419]
100934336  CXCR4; C-X-C chemokine receptor type 4 isoform X1 [KO:K04189]
100934443  CCR7; C-C chemokine receptor type 7 [KO:K04182]
100934473  EDA2R; tumor necrosis factor receptor superfamily member 27 [KO:K05163]
100934563  GDF9; growth/differentiation factor 9 [KO:K22673]
100934579  LIFR; leukemia inhibitory factor receptor [KO:K05058]
100935026  TNFRSF17; tumor necrosis factor receptor superfamily member 17 isoform X1 [KO:K05153]
100935038  EDAR; tumor necrosis factor receptor superfamily member EDAR isoform X1 [KO:K05162]
100935068  [KO:K05429]
100935094  BMP2; bone morphogenetic protein 2 [KO:K21283]
100935199  [KO:K24382]
100935278  IL31RA; interleukin-31 receptor subunit alpha isoform X1 [KO:K22630]
100935349  CD40; tumor necrosis factor receptor superfamily member 5 [KO:K03160]
105749071  [KO:K04722]
105749132  IL1A; interleukin-1 alpha [KO:K04383]
105749159  IL9; LOW QUALITY PROTEIN: interleukin-9 [KO:K05432]
105749219  FAS; tumor necrosis factor receptor superfamily member 6 [KO:K04390]
105749415  IL12RB1; LOW QUALITY PROTEIN: interleukin-12 receptor subunit beta-1 [KO:K05063]
105749426  CCL25; C-C motif chemokine 25 [KO:K13072]
105749464  [KO:K05418]
105749505  TNFRSF13B; tumor necrosis factor receptor superfamily member 13B [KO:K05150]
105749532  [KO:K05073]
105749698  TSLP; LOW QUALITY PROTEIN: thymic stromal lymphopoietin [KO:K05436]
105749716  IL33; interleukin-33 [KO:K12967]
105749783  [KO:K05504]
105749994  CSF2RA; granulocyte-macrophage colony-stimulating factor receptor subunit alpha [KO:K05066]
105749995  [KO:K04737]
105749996  CRLF2; cytokine receptor-like factor 2 [KO:K05078]
105750026  TNFSF11; tumor necrosis factor ligand superfamily member 11 [KO:K05473]
105750042  TNFSF10; tumor necrosis factor ligand superfamily member 10 [KO:K04721]
105750087  IFNAR2; interferon alpha/beta receptor 2 isoform X1 [KO:K05131]
105750536  [KO:K05408]
105750562  THPO; thrombopoietin [KO:K06854]
105750580  [KO:K12964]
105750636  CXCL16; C-X-C motif chemokine 16 [KO:K10035]
105750683  IFNG; interferon gamma [KO:K04687]
105750684  CSF2RB; cytokine receptor common subunit beta isoform X1 [KO:K04738]
105750697  IL15RA; interleukin-15 receptor subunit alpha [KO:K05074]
105750698  IL2RA; interleukin-2 receptor subunit alpha isoform X1 [KO:K05068]
105750762  IL6; interleukin-6 [KO:K05405]
105750853  [KO:K12671]
105750855  CXCL13; C-X-C motif chemokine 13 [KO:K10032]
105751011  IL21; interleukin-21 [KO:K05434]
105751035  CXCL9; C-X-C motif chemokine 9 [KO:K05416]
111719790  [KO:K05482]
111719907  [KO:K05152]
111719911  TNFRSF8; tumor necrosis factor receptor superfamily member 8 isoform X1 [KO:K05145]
111719928  TNFRSF18; tumor necrosis factor receptor superfamily member 18 [KO:K05154]
111719929  TNFRSF4; tumor necrosis factor receptor superfamily member 4 [KO:K05142]
111720388  TNFSF4; tumor necrosis factor ligand superfamily member 4 [KO:K05469]
111720637  [KO:K05474]
111720800  [KO:K05514]
111720829  IL13; interleukin-13 [KO:K05435]
111720949  [KO:K05408]
111720994  IFNGR1; interferon gamma receptor 1 [KO:K05132]
111721210  TNFRSF13C; LOW QUALITY PROTEIN: tumor necrosis factor receptor superfamily member 13C [KO:K05151]
111721298  [KO:K10032]
111721697  TNFSF15; tumor necrosis factor ligand superfamily member 15 [KO:K05478]
116420274  BMP15; bone morphogenetic protein 15 [KO:K05498]
116420560  IL7; interleukin-7 [KO:K05431]
116420796  GDF1; embryonic growth/differentiation factor 1 [KO:K05495]
116420799  [KO:K05504]
116420987  [KO:K05414]
116420989  [KO:K05414]
116421208  GDF7; growth/differentiation factor 7 [KO:K20013]
116421930  GDF2; growth/differentiation factor 2 [KO:K05503]
116422421  CXCR5; C-X-C chemokine receptor type 5 isoform X1 [KO:K04190]
116422647  [KO:K22669]
116422648  [KO:K22669]
116422649  [KO:K22669]
116422650  [KO:K22669]
116422651  [KO:K22669]
116422895  CXCL17; C-X-C motif chemokine 17 [KO:K22627]
116423442  [KO:K12964]
Reference
  Authors
Turner MD, Nedjai B, Hurst T, Pennington DJ
  Title
Cytokines and chemokines: At the crossroads of cell signalling and inflammatory disease.
  Journal
Biochim Biophys Acta 1843:2563-2582 (2014)
DOI:10.1016/j.bbamcr.2014.05.014
Reference
  Authors
Brocker C, Thompson D, Matsumoto A, Nebert DW, Vasiliou V
  Title
Evolutionary divergence and functions of the human interleukin (IL) gene family.
  Journal
Hum Genomics 5:30-55 (2010)
DOI:10.1186/1479-7364-5-1-30
Reference
  Authors
Akdis M, Aab A, Altunbulakli C, Azkur K, Costa RA, Crameri R, Duan S, Eiwegger T, Eljaszewicz A, Ferstl R, Frei R, Garbani M, Globinska A, Hess L, Huitema C, Kubo T, Komlosi Z, Konieczna P, Kovacs N, Kucuksezer UC, Meyer N, Morita H, Olzhausen J, O'Mahony L, Pezer M, Prati M, Rebane A, Rhyner C, Rinaldi A, Sokolowska M, Stanic B, Sugita K, Treis A, van de Veen W, Wanke K, Wawrzyniak M, Wawrzyniak P, Wirz OF, Zakzuk JS, Akdis CA
  Title
Interleukins (from IL-1 to IL-38), interferons, transforming growth factor beta, and TNF-alpha: Receptors, functions, and roles in diseases.
  Journal
J Allergy Clin Immunol 138:984-1010 (2016)
DOI:10.1016/j.jaci.2016.06.033
Reference
  Authors
Boulanger MJ, Garcia KC
  Title
Shared cytokine signaling receptors: structural insights from the gp130 system.
  Journal
Adv Protein Chem 68:107-46 (2004)
DOI:10.1016/S0065-3233(04)68004-1
Reference
  Authors
Allan SM, Tyrrell PJ, Rothwell NJ
  Title
Interleukin-1 and neuronal injury.
  Journal
Nat Rev Immunol 5:629-40 (2005)
DOI:10.1038/nri1664
Reference
  Authors
Lopetuso LR, Chowdhry S, Pizarro TT
  Title
Opposing Functions of Classic and Novel IL-1 Family Members in Gut Health and Disease.
  Journal
Front Immunol 4:181 (2013)
DOI:10.3389/fimmu.2013.00181
Reference
  Authors
Iwakura Y, Ishigame H, Saijo S, Nakae S
  Title
Functional specialization of interleukin-17 family members.
  Journal
Immunity 34:149-62 (2011)
DOI:10.1016/j.immuni.2011.02.012
Reference
  Authors
Fischer P, Hilfiker-Kleiner D
  Title
Survival pathways in hypertrophy and heart failure: the gp130-STAT3 axis.
  Journal
Basic Res Cardiol 102:279-97 (2007)
DOI:10.1007/s00395-007-0658-z
Reference
  Authors
Richards CD
  Title
The enigmatic cytokine oncostatin m and roles in disease.
  Journal
ISRN Inflamm 2013:512103 (2013)
DOI:10.1155/2013/512103
Reference
  Authors
Zhang Q, Putheti P, Zhou Q, Liu Q, Gao W
  Title
Structures and biological functions of IL-31 and IL-31 receptors.
  Journal
Cytokine Growth Factor Rev 19:347-56 (2008)
DOI:10.1016/j.cytogfr.2008.08.003
Reference
  Authors
Meenhuis A, Verwijmeren C, Roovers O, Touw IP
  Title
The deubiquitinating enzyme DUB2A enhances CSF3 signalling by attenuating lysosomal routing of the CSF3 receptor.
  Journal
Biochem J 434:343-51 (2011)
DOI:10.1042/BJ20101628
Reference
  Authors
de Weerd NA, Nguyen T
  Title
The interferons and their receptors--distribution and regulation.
  Journal
Immunol Cell Biol 90:483-91 (2012)
DOI:10.1038/icb.2012.9
Reference
  Authors
Aggarwal BB
  Title
Signalling pathways of the TNF superfamily: a double-edged sword.
  Journal
Nat Rev Immunol 3:745-56 (2003)
DOI:10.1038/nri1184
Reference
  Authors
Ashkenazi A
  Title
Targeting death and decoy receptors of the tumour-necrosis factor superfamily.
  Journal
Nat Rev Cancer 2:420-30 (2002)
DOI:10.1038/nrc821
Reference
  Authors
Seeger P, Musso T, Sozzani S
  Title
The TGF-beta superfamily in dendritic cell biology.
  Journal
Cytokine Growth Factor Rev 26:647-57 (2015)
DOI:10.1016/j.cytogfr.2015.06.002
Reference
  Authors
Wakefield LM, Hill CS
  Title
Beyond TGFbeta: roles of other TGFbeta superfamily members in cancer.
  Journal
Nat Rev Cancer 13:328-41 (2013)
DOI:10.1038/nrc3500
Reference
  Authors
Mueller TD, Nickel J
  Title
Promiscuity and specificity in BMP receptor activation.
  Journal
FEBS Lett 586:1846-59 (2012)
DOI:10.1016/j.febslet.2012.02.043
KO pathway
ko04060   

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