KEGG   PATHWAY: aml04060
Entry
aml04060                    Pathway                                
Name
Cytokine-cytokine receptor interaction - Ailuropoda melanoleuca (giant panda)
Description
Cytokines are soluble extracellular proteins or glycoproteins that are crucial intercellular regulators and mobilizers of cells engaged in innate as well as adaptive inflammatory host defenses, cell growth, differentiation, cell death, angiogenesis, and development and repair processes aimed at the restoration of homeostasis. Cytokines are released by various cells in the body, usually in response to an activating stimulus, and they induce responses through binding to specific receptors on the cell surface of target cells. Cytokines can be grouped by structure into different families and their receptors can likewise be grouped.
Class
Environmental Information Processing; Signaling molecules and interaction
Pathway map
aml04060  Cytokine-cytokine receptor interaction
aml04060

Organism
Ailuropoda melanoleuca (giant panda) [GN:aml]
Gene
105240106  CCL1; C-C motif chemokine 1 [KO:K05514]
105238779  CCL25; C-C motif chemokine 25 isoform X1 [KO:K13072]
100481549  CCL19; C-C motif chemokine 19 [KO:K05512]
100480794  CCL21; C-C motif chemokine 21 isoform X1 [KO:K16062]
100469047  C-C motif chemokine 3 [KO:K05408]
100469295  C-C motif chemokine 3 isoform X1 [KO:K05408]
100464006  regakine-1-like [KO:K05408]
100468796  C-C motif chemokine 4 [KO:K12964]
100470736  CCL17; C-C motif chemokine 17 [KO:K21083]
100470232  CCL22; C-C motif chemokine 22 [KO:K21095]
100463753  CCL5; C-C motif chemokine 5 [KO:K12499]
100474856  C-C motif chemokine 8 [KO:K16596]
100467253  CCL16; C-C motif chemokine 16 [KO:K21093]
100468009  C-C motif chemokine 14-like isoform X1 [KO:K05511]
117795398  C-C motif chemokine 15-like isoform X1 [KO:K05511]
100475112  C-C motif chemokine 13 [KO:K16595]
100474600  C-C motif chemokine 7 [KO:K05509]
100474348  C-C motif chemokine 2 [KO:K14624]
100465518  CCL24; C-C motif chemokine 24 [KO:K21097]
100465767  CCL26; C-C motif chemokine 26 [KO:K21096]
100480543  CCL27; C-C motif chemokine 27 [KO:K16598]
109488513  uncharacterized protein LOC109488513 isoform X2 [KO:K16598]
100474043  CCL28; C-C motif chemokine 28 [KO:K05513]
105239958  CCL20; C-C motif chemokine 20 isoform X1 [KO:K14625]
100463732  growth-regulated alpha protein [KO:K05505]
100466241  growth-regulated protein homolog gamma-like isoform X1 [KO:K05505]
100471490  growth-regulated alpha protein [KO:K05505]
100472054  CXCL8; interleukin-8 [KO:K10030]
100484431  platelet basic protein isoform X1 [KO:K10029]
100484936  platelet factor 4-like [KO:K05407]
100469185  CXCL9; C-X-C motif chemokine 9 isoform X2 [KO:K05416]
100469693  CXCL10; C-X-C motif chemokine 10 [KO:K12671]
100469949  CXCL11; C-X-C motif chemokine 11 [KO:K12672]
105234669  CXCL13; C-X-C motif chemokine 13 [KO:K10032]
100482629  CXCL12; stromal cell-derived factor 1 isoform X2 [KO:K10031]
100470282  CXCL16; C-X-C motif chemokine 16 [KO:K10035]
100478539  CXCL14; C-X-C motif chemokine 14 [KO:K10033]
100473806  CXCL17; C-X-C motif chemokine 17 [KO:K22627]
100482046  cytokine SCM-1 beta [KO:K22675]
100470482  CX3CL1; fractalkine isoform X2 [KO:K05508]
100480862  IL2; interleukin-2 precursor [KO:K05429]
100482473  IL4; interleukin-4 precursor [KO:K05430]
100481194  IL7; interleukin-7 [KO:K05431]
105237562  IL9; interleukin-9 [KO:K05432]
100484790  IL15; interleukin-15 precursor [KO:K05433]
100480614  IL21; interleukin-21 [KO:K05434]
100474287  TSLP; thymic stromal lymphopoietin [KO:K05436]
100473242  interleukin-3 [KO:K04736]
100482219  IL5; interleukin-5 [KO:K05428]
100473502  uncharacterized protein LOC100473502 [KO:K05427]
109488324  CSF2; granulocyte-macrophage colony-stimulating factor [KO:K05427]
100474520  IL13; LOW QUALITY PROTEIN: interleukin-13 [KO:K05435]
100483785  EPO; erythropoietin [KO:K05437]
100471532  GH1; somatotropin precursor [KO:K05438]
100481524  PRL; prolactin precursor [KO:K05439]
100469915  THPO; thrombopoietin isoform X2 [KO:K06854]
100481290  CSF3; granulocyte colony-stimulating factor [KO:K05423]
100474605  LEP; leptin precursor [KO:K05424]
100477151  IL6; interleukin-6 precursor [KO:K05405]
117803984  interleukin-6-like [KO:K05405]
100478943  IL11; interleukin-11 [KO:K05417]
100470471  IL12A; interleukin-12 subunit alpha isoform X2 [KO:K05406]
100477772  IL12B; interleukin-12 subunit beta [KO:K05425]
100471919  IL23A; interleukin-23 subunit alpha [KO:K05426]
100472637  IL27; interleukin-27 subunit alpha [KO:K22629]
100464948  EBI3; interleukin-27 subunit beta isoform X2 [KO:K24476]
100479792  IL31; interleukin-31 [KO:K22631]
100470361  CLCF1; cardiotrophin-like cytokine factor 1 [KO:K05421]
100477429  CNTF; ciliary neurotrophic factor [KO:K05420]
100482951  CTF1; cardiotrophin-1 [KO:K24382]
100483416  LIF; leukemia inhibitory factor isoform X2 [KO:K05419]
100483167  OSM; oncostatin-M [KO:K05418]
100481671  IL10; interleukin-10 [KO:K05443]
100483678  IL19; interleukin-19 isoform X2 [KO:K05444]
100483429  IL20; interleukin-20 [KO:K22667]
100483182  IL24; interleukin-24 [KO:K22668]
100480746  IL22; interleukin-22 [KO:K05445]
100482502  IL26; interleukin-26 [KO:K05446]
100466034  IFNL3; interferon lambda-3 [KO:K22669]
100482725  interferon lambda-1 [KO:K05447]
100469032  interferon lambda-1 [KO:K05447]
100476812  interferon alpha-2 [KO:K05414]
100477312  interferon alpha-1/2 [KO:K05414]
100477562  LOW QUALITY PROTEIN: interferon alpha-1/2 [KO:K05414]
100478321  interferon alpha-1/2 [KO:K05414]
100478068  interferon alpha-like [KO:K05414]
100476556  IFNB1; interferon beta [KO:K05415]
100475503  IFNK; interferon kappa [KO:K05441]
100471673  IFNE; LOW QUALITY PROTEIN: interferon epsilon [KO:K05442]
100462659  IFNG; interferon gamma precursor [KO:K04687]
100481122  IL1A; interleukin-1 alpha [KO:K04383]
100480874  IL1B; interleukin-1 beta [KO:K04519]
100480371  IL1RN; interleukin-1 receptor antagonist protein isoform X2 [KO:K05481]
100480625  interleukin-36 receptor antagonist protein isoform X1 [KO:K05483]
100483708  interleukin-36 beta isoform X1 [KO:K05486]
100483962  interleukin-36 gamma isoform X1 [KO:K05487]
100483461  IL1F10; interleukin-1 family member 10 isoform X1 [KO:K05488]
100484109  IL18; interleukin-18 [KO:K05482]
100479637  IL33; interleukin-33 [KO:K12967]
100483488  IL17A; interleukin-17A [KO:K05489]
100465566  IL17F; interleukin-17F isoform X2 [KO:K05494]
100473778  IL17B; interleukin-17B isoform X1 [KO:K05490]
100467294  IL17C; interleukin-17C [KO:K05491]
105240206  IL17D; interleukin-17D [KO:K05492]
100470437  IL25; interleukin-25 [KO:K05493]
100467740  IL16; pro-interleukin-16 isoform X3 [KO:K22628]
105234917  IL32; LOW QUALITY PROTEIN: interleukin-32 [KO:K22632]
100464498  IL34; interleukin-34 isoform X1 [KO:K22633]
100467411  CSF1; macrophage colony-stimulating factor 1 isoform X2 [KO:K05453]
100471563  TNF; tumor necrosis factor [KO:K03156]
100471816  LTA; lymphotoxin-alpha [KO:K05468]
100467628  LTB; lymphotoxin-beta isoform X1 [KO:K03157]
100472140  TNFSF14; tumor necrosis factor ligand superfamily member 14 [KO:K05477]
100468235  FASLG; tumor necrosis factor ligand superfamily member 6 [KO:K04389]
100473862  TNFSF15; tumor necrosis factor ligand superfamily member 15 isoform X1 [KO:K05478]
100463573  TNFSF10; tumor necrosis factor ligand superfamily member 10 [KO:K04721]
100475055  EDA; ectodysplasin-A isoform X3 [KO:K05480]
100469695  NGF; beta-nerve growth factor [KO:K02582]
100483079  TNFSF11; tumor necrosis factor ligand superfamily member 11 [KO:K05473]
117796995  tumor necrosis factor ligand superfamily member 12-like [KO:K05474]
100475352  CD70; CD70 antigen isoform X1 [KO:K05470]
100473610  TNFSF8; tumor necrosis factor ligand superfamily member 8 [KO:K05471]
100467917  CD40LG; CD40 ligand [KO:K03161]
105241361  TNFSF9; tumor necrosis factor ligand superfamily member 9 [KO:K05472]
100468487  TNFSF4; tumor necrosis factor ligand superfamily member 4 [KO:K05469]
100471754  TNFSF18; tumor necrosis factor ligand superfamily member 18 [KO:K05479]
100466355  tumor necrosis factor ligand superfamily member 13 isoform X1 [KO:K05475]
100475623  TNFSF13B; tumor necrosis factor ligand superfamily member 13B [KO:K05476]
100470703  TGFB1; transforming growth factor beta-1 proprotein isoform X1 [KO:K13375]
100463584  TGFB2; transforming growth factor beta-2 proprotein isoform X2 [KO:K13376]
100475861  TGFB3; transforming growth factor beta-3 proprotein isoform X1 [KO:K13377]
100477875  GDF15; growth/differentiation factor 15 [KO:K05504]
100484152  GDF2; growth/differentiation factor 2 [KO:K05503]
100478772  BMP10; bone morphogenetic protein 10 [KO:K22670]
100470029  INHA; inhibin alpha chain [KO:K05500]
100468139  BMP3; bone morphogenetic protein 3 [KO:K05496]
100484403  GDF10; growth/differentiation factor 10 [KO:K22674]
100476179  GDF11; growth/differentiation factor 11 [KO:K22679]
100472102  MSTN; growth/differentiation factor 8 [KO:K05497]
100463717  INHBA; inhibin beta A chain [KO:K04667]
100484001  INHBB; LOW QUALITY PROTEIN: inhibin beta B chain [KO:K22687]
100478281  embryonic growth/differentiation factor 1 [KO:K05495]
100474590  GDF3; LOW QUALITY PROTEIN: growth/differentiation factor 3 [KO:K22672]
100484470  LOW QUALITY PROTEIN: growth/differentiation factor 3-like [KO:K22672]
100481810  NODAL; nodal homolog isoform X1 [KO:K04666]
100482975  GDF9; growth/differentiation factor 9 isoform X1 [KO:K22673]
100477882  INHBC; inhibin beta C chain [KO:K22688]
100478138  INHBE; inhibin beta E chain [KO:K22689]
105240549  AMH; LOW QUALITY PROTEIN: muellerian-inhibiting factor [KO:K04665]
100465860  BMP2; bone morphogenetic protein 2 isoform X2 [KO:K21283]
100477715  BMP4; bone morphogenetic protein 4 isoform X1 [KO:K04662]
100483924  GDF5; growth/differentiation factor 5 [KO:K04664]
117803774  GDF6; growth/differentiation factor 6 [KO:K20012]
105235739  GDF7; growth/differentiation factor 7 [KO:K20013]
100473231  BMP15; bone morphogenetic protein 15 [KO:K05498]
100483844  BMP5; bone morphogenetic protein 5 [KO:K04663]
100481406  BMP6; bone morphogenetic protein 6 [KO:K16620]
100475946  BMP7; bone morphogenetic protein 7 [KO:K16621]
100466781  BMP8A; bone morphogenetic protein 8A [KO:K16622]
100481381  CCR8; C-C chemokine receptor type 8 [KO:K04183]
100464037  CCR9; C-C chemokine receptor type 9 [KO:K04184]
100478180  ACKR4; atypical chemokine receptor 4 [KO:K04186]
100464680  CCR7; C-C chemokine receptor type 7 isoform X1 [KO:K04182]
100475059  CCR4; C-C chemokine receptor type 4 [KO:K04179]
100465045  C-C chemokine receptor type 5 [KO:K04180]
100464796  C-C chemokine receptor type 3 [KO:K04178]
100484065  CCR2; C-C chemokine receptor type 2 [KO:K04177]
100483811  C-C chemokine receptor type 1 [KO:K04176]
100480758  CCR10; C-C chemokine receptor type 10 isoform X2 [KO:K04185]
100481089  CCR6; C-C chemokine receptor type 6 [KO:K04181]
100470159  C-X-C chemokine receptor type 2 isoform X1 [KO:K04175]
100470409  CXCR2; LOW QUALITY PROTEIN: C-X-C chemokine receptor type 2 [KO:K05050]
100466219  C-X-C chemokine receptor type 2 [KO:K05050]
100475682  CXCR3; C-X-C chemokine receptor type 3 [KO:K04188]
100466449  CXCR5; C-X-C chemokine receptor type 5 isoform X1 [KO:K04190]
100468194  CXCR4; C-X-C chemokine receptor type 4 [KO:K04189]
100470730  ACKR3; atypical chemokine receptor 3 isoform X2 [KO:K04304]
100464292  CXCR6; C-X-C chemokine receptor type 6 [KO:K04191]
100464543  XCR1; chemokine XC receptor 1 [KO:K04193]
100481132  CX3CR1; CX3C chemokine receptor 1 [KO:K04192]
100466247  IL2RA; interleukin-2 receptor subunit alpha isoform X3 [KO:K05068]
100478292  IL2RB; interleukin-2 receptor subunit beta [KO:K05069]
100468126  IL2RG; cytokine receptor common subunit gamma isoform X2 [KO:K05070]
100476095  IL4R; interleukin-4 receptor subunit alpha isoform X1 [KO:K05071]
100477617  IL7R; interleukin-7 receptor subunit alpha [KO:K05072]
105238043  IL9R; interleukin-9 receptor [KO:K05073]
105238122  IL15RA; interleukin-15 receptor subunit alpha isoform X1 [KO:K05074]
100467688  IL21R; interleukin-21 receptor [KO:K05075]
100470015  CRLF2; cytokine receptor-like factor 2 isoform X1 [KO:K05078]
105238362  IL3RA; interleukin-3 receptor subunit alpha [KO:K04737]
100477536  CSF2RB; cytokine receptor common subunit beta [KO:K04738]
100478972  IL5RA; interleukin-5 receptor subunit alpha [KO:K05067]
100469756  CSF2RA; granulocyte-macrophage colony-stimulating factor receptor subunit alpha [KO:K05066]
105238364  granulocyte-macrophage colony-stimulating factor receptor subunit alpha-like [KO:K05066]
100477299  IL13RA1; interleukin-13 receptor subunit alpha-1 [KO:K05076]
100473482  IL13RA2; interleukin-13 receptor subunit alpha-2 [KO:K05077]
100484014  EPOR; erythropoietin receptor [KO:K05079]
100422780  GHR; growth hormone receptor precursor [KO:K05080]
100481840  PRLR; prolactin receptor isoform X1 [KO:K05081]
100476412  MPL; thrombopoietin receptor isoform X1 [KO:K05082]
100464681  CSF3R; granulocyte colony-stimulating factor receptor [KO:K05061]
100470278  LEPR; leptin receptor [KO:K05062]
100471277  IL6R; interleukin-6 receptor subunit alpha isoform X1 [KO:K05055]
100483131  IL6ST; interleukin-6 receptor subunit beta isoform X1 [KO:K05060]
100481047  IL11RA; interleukin-11 receptor subunit alpha [KO:K05056]
100474774  IL12RB1; interleukin-12 receptor subunit beta-1 isoform X2 [KO:K05063]
100478166  IL12RB2; interleukin-12 receptor subunit beta-2 isoform X2 [KO:K05064]
100478419  IL23R; interleukin-23 receptor [KO:K05065]
100475725  IL27RA; interleukin-27 receptor subunit alpha [KO:K19598]
100483628  IL31RA; LOW QUALITY PROTEIN: interleukin-31 receptor subunit alpha [KO:K22630]
100478954  CNTFR; ciliary neurotrophic factor receptor subunit alpha isoform X1 [KO:K05059]
100463863  LIFR; leukemia inhibitory factor receptor isoform X1 [KO:K05058]
100465053  OSMR; oncostatin-M-specific receptor subunit beta isoform X1 [KO:K05057]
100469546  IL10RA; interleukin-10 receptor subunit alpha [KO:K05134]
109488333  IL10RB; interleukin-10 receptor subunit beta isoform X1 [KO:K05135]
100476037  IL20RA; interleukin-20 receptor subunit alpha isoform X2 [KO:K05136]
100472789  IL20RB; interleukin-20 receptor subunit beta [KO:K05137]
100478388  IL22RA1; interleukin-22 receptor subunit alpha-1 isoform X1 [KO:K05138]
100473416  IFNLR1; interferon lambda receptor 1 [KO:K05140]
100481921  IFNAR1; interferon alpha/beta receptor 1 [KO:K05130]
100482679  IFNAR2; interferon alpha/beta receptor 2 [KO:K05131]
100473768  IFNGR1; interferon gamma receptor 1 [KO:K05132]
100481672  IFNGR2; interferon gamma receptor 2 isoform X1 [KO:K05133]
100472991  IL1R1; interleukin-1 receptor type 1 isoform X1 [KO:K04386]
100472192  IL1RAP; interleukin-1 receptor accessory protein isoform X2 [KO:K04723]
100475938  IL1R2; interleukin-1 receptor type 2 isoform X2 [KO:K04387]
100476189  IL1RL2; LOW QUALITY PROTEIN: interleukin-1 receptor-like 2 [KO:K05172]
100476694  IL18R1; interleukin-18 receptor 1 [KO:K05173]
100476941  IL18RAP; interleukin-18 receptor accessory protein isoform X1 [KO:K05174]
100476444  IL1RL1; interleukin-1 receptor-like 1 isoform X1 [KO:K05171]
100479218  IL17RA; interleukin-17 receptor A isoform X3 [KO:K05164]
100473461  IL17RC; interleukin-17 receptor C isoform X1 [KO:K05166]
100467954  IL17RB; interleukin-17 receptor B isoform X1 [KO:K05165]
100473718  IL17RE; interleukin-17 receptor E isoform X1 [KO:K05168]
100482689  CD4; T-cell surface glycoprotein CD4 isoform X2 [KO:K06454]
100472252  CSF1R; macrophage colony-stimulating factor 1 receptor isoform X2 [KO:K05090] [EC:2.7.10.1]
100479926  TNFRSF1A; tumor necrosis factor receptor superfamily member 1A [KO:K03158]
100473387  TNFRSF1B; tumor necrosis factor receptor superfamily member 1B isoform X1 [KO:K05141]
100479494  LTBR; tumor necrosis factor receptor superfamily member 3 isoform X1 [KO:K03159]
100476581  TNFRSF14; tumor necrosis factor receptor superfamily member 14 isoform X1 [KO:K05152]
100464518  TNFRSF6B; tumor necrosis factor receptor superfamily member 6B isoform X1 [KO:K05143]
100473767  FAS; tumor necrosis factor receptor superfamily member 6 [KO:K04390]
100472525  TNFRSF25; tumor necrosis factor receptor superfamily member 25 isoform X1 [KO:K05160]
105235183  tumor necrosis factor receptor superfamily member 10A-like [KO:K04722]
100467484  TNFRSF21; tumor necrosis factor receptor superfamily member 21 isoform X1 [KO:K05157]
100475348  EDAR; tumor necrosis factor receptor superfamily member EDAR isoform X2 [KO:K05162]
100482463  EDA2R; tumor necrosis factor receptor superfamily member 27 isoform X2 [KO:K05163]
100478241  NGFR; tumor necrosis factor receptor superfamily member 16 [KO:K02583]
100465761  TNFRSF11B; tumor necrosis factor receptor superfamily member 11B [KO:K05148]
100483336  TNFRSF11A; tumor necrosis factor receptor superfamily member 11A [KO:K05147]
100477370  TNFRSF12A; tumor necrosis factor receptor superfamily member 12A [KO:K05149]
100484193  CD27; CD27 antigen isoform X1 [KO:K05144]
100473132  TNFRSF8; tumor necrosis factor receptor superfamily member 8 isoform X1 [KO:K05145]
100476345  CD40; tumor necrosis factor receptor superfamily member 5 isoform X2 [KO:K03160]
100475396  TNFRSF9; tumor necrosis factor receptor superfamily member 9 isoform X1 [KO:K05146]
100469971  TNFRSF4; tumor necrosis factor receptor superfamily member 4 isoform X2 [KO:K05142]
100472974  TNFRSF18; tumor necrosis factor receptor superfamily member 18 isoform X1 [KO:K05154]
100464516  TNFRSF17; tumor necrosis factor receptor superfamily member 17 [KO:K05153]
100477179  TNFRSF13B; tumor necrosis factor receptor superfamily member 13B [KO:K05150]
100466414  TNFRSF19; tumor necrosis factor receptor superfamily member 19 [KO:K05155]
100480566  RELT; tumor necrosis factor receptor superfamily member 19L isoform X1 [KO:K05156]
100465880  RELL2; RELT-like protein 2 isoform X1 [KO:K26541]
100470287  RELL1; RELT-like protein 1 isoform X1 [KO:K26541]
100475698  TGFBR1; TGF-beta receptor type-1 [KO:K04674] [EC:2.7.11.30]
100482939  TGFBR2; TGF-beta receptor type-2 isoform X1 [KO:K04388] [EC:2.7.11.30]
100482358  ACVRL1; serine/threonine-protein kinase receptor R3 [KO:K13594] [EC:2.7.11.30]
100472026  ACVR2A; activin receptor type-2A isoform X2 [KO:K04670] [EC:2.7.11.30]
100483427  BMPR2; bone morphogenetic protein receptor type-2 [KO:K04671] [EC:2.7.11.30]
100477787  ACVR2B; activin receptor type-2B isoform X1 [KO:K13596] [EC:2.7.11.30]
100482103  ACVR1B; activin receptor type-1B [KO:K13567] [EC:2.7.11.30]
100476073  ACVR1C; activin receptor type-1C [KO:K13568] [EC:2.7.11.30]
100476325  ACVR1; activin receptor type-1 isoform X1 [KO:K04675] [EC:2.7.11.30]
100475241  AMHR2; anti-Muellerian hormone type-2 receptor isoform X7 [KO:K04672] [EC:2.7.11.30]
100472999  BMPR1A; bone morphogenetic protein receptor type-1A [KO:K04673] [EC:2.7.11.30]
100467049  BMPR1B; bone morphogenetic protein receptor type-1B isoform X2 [KO:K13578] [EC:2.7.11.30]
Reference
  Authors
Turner MD, Nedjai B, Hurst T, Pennington DJ
  Title
Cytokines and chemokines: At the crossroads of cell signalling and inflammatory disease.
  Journal
Biochim Biophys Acta 1843:2563-2582 (2014)
DOI:10.1016/j.bbamcr.2014.05.014
Reference
  Authors
Brocker C, Thompson D, Matsumoto A, Nebert DW, Vasiliou V
  Title
Evolutionary divergence and functions of the human interleukin (IL) gene family.
  Journal
Hum Genomics 5:30-55 (2010)
DOI:10.1186/1479-7364-5-1-30
Reference
  Authors
Akdis M, Aab A, Altunbulakli C, Azkur K, Costa RA, Crameri R, Duan S, Eiwegger T, Eljaszewicz A, Ferstl R, Frei R, Garbani M, Globinska A, Hess L, Huitema C, Kubo T, Komlosi Z, Konieczna P, Kovacs N, Kucuksezer UC, Meyer N, Morita H, Olzhausen J, O'Mahony L, Pezer M, Prati M, Rebane A, Rhyner C, Rinaldi A, Sokolowska M, Stanic B, Sugita K, Treis A, van de Veen W, Wanke K, Wawrzyniak M, Wawrzyniak P, Wirz OF, Zakzuk JS, Akdis CA
  Title
Interleukins (from IL-1 to IL-38), interferons, transforming growth factor beta, and TNF-alpha: Receptors, functions, and roles in diseases.
  Journal
J Allergy Clin Immunol 138:984-1010 (2016)
DOI:10.1016/j.jaci.2016.06.033
Reference
  Authors
Boulanger MJ, Garcia KC
  Title
Shared cytokine signaling receptors: structural insights from the gp130 system.
  Journal
Adv Protein Chem 68:107-46 (2004)
DOI:10.1016/S0065-3233(04)68004-1
Reference
  Authors
Allan SM, Tyrrell PJ, Rothwell NJ
  Title
Interleukin-1 and neuronal injury.
  Journal
Nat Rev Immunol 5:629-40 (2005)
DOI:10.1038/nri1664
Reference
  Authors
Lopetuso LR, Chowdhry S, Pizarro TT
  Title
Opposing Functions of Classic and Novel IL-1 Family Members in Gut Health and Disease.
  Journal
Front Immunol 4:181 (2013)
DOI:10.3389/fimmu.2013.00181
Reference
  Authors
Iwakura Y, Ishigame H, Saijo S, Nakae S
  Title
Functional specialization of interleukin-17 family members.
  Journal
Immunity 34:149-62 (2011)
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