KEGG   PATHWAY: ecra05168
Entry
ecra05168                   Pathway                                
Name
Herpes simplex virus 1 infection - Etheostoma cragini (Arkansas darter)
Description
Herpes simplex virus 1(HSV-1) is a common human pathogen, which initially infects orofacial mucosal surfaces. The virus replicates in epithelial cells at these sites, causing clinically overt disease characterized by vesicular lesions. HSV-1 then penetrates to the nervous system and establishes latency in sensory neurons. Throughout the lifetime of the host, HSV-1 may reactivate from its latent state and reinitiate a lytic infection cycle. HSV-1 has developed various mechanisms to escape its host innate immune responses and increased its capacity to replicate and to persist. ICP34.5, ICP0, ICP27, Us11 and Vhs (UL41) are the proteins involved in viral interference.
Class
Human Diseases; Infectious disease: viral
Pathway map
ecra05168  Herpes simplex virus 1 infection
ecra05168

Organism
Etheostoma cragini (Arkansas darter) [GN:ecra]
Gene
117946791  tnfb; tumor necrosis factor b (TNF superfamily, member 2) [KO:K05468]
117958760  tnfsf14; tumor necrosis factor ligand superfamily member 14 [KO:K05477]
117959338  tumor necrosis factor ligand superfamily member 10-like isoform X1 [KO:K05477]
117947200  tumor necrosis factor receptor superfamily member 14-like isoform X1 [KO:K05152]
117947201  tumor necrosis factor receptor superfamily member 14-like isoform X1 [KO:K05152]
117948240  tumor necrosis factor receptor superfamily member 14-like [KO:K05152]
117945290  TNF receptor-associated factor 2-like isoform X1 [KO:K03173] [EC:2.3.2.27]
117958915  traf2b; TNF receptor-associated factor 2 [KO:K03173] [EC:2.3.2.27]
117959390  TNF receptor-associated factor 2-like [KO:K03173] [EC:2.3.2.27]
117945478  ikbkb; inhibitor of nuclear factor kappa-B kinase subunit beta [KO:K07209] [EC:2.7.11.10]
117936511  inhibitor of nuclear factor kappa-B kinase subunit alpha-like [KO:K04467] [EC:2.7.11.10]
117960217  inhibitor of nuclear factor kappa-B kinase subunit alpha-like isoform X1 [KO:K04467] [EC:2.7.11.10]
117947160  ikbkg; NF-kappa-B essential modulator isoform X1 [KO:K07210]
117961674  NF-kappa-B inhibitor alpha-like [KO:K04734]
117935665  nfkbiab; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b isoform X1 [KO:K04734]
117934772  rela; transcription factor p65 isoform X1 [KO:K04735]
117955162  birc2; baculoviral IAP repeat-containing protein 2 [KO:K16060]
117955167  nectin1a; nectin cell adhesion molecule 1a isoform X1 [KO:K06081]
117952899  si:ch211-214p13.3; nectin-1 [KO:K06081]
117941654  nectin1b; nectin cell adhesion molecule 1b isoform X1 [KO:K06081]
117946230  nectin-2-like isoform X1 [KO:K06531]
117959143  ptpn11a; tyrosine-protein phosphatase non-receptor type 11 isoform X1 [KO:K07293] [EC:3.1.3.48]
117947049  tyrosine-protein phosphatase non-receptor type 11-like isoform X1 [KO:K07293] [EC:3.1.3.48]
117942798  integrin alpha-5-like [KO:K06484]
117946995  itga5; integrin alpha-5 [KO:K06484]
117936817  integrin beta-3-like [KO:K06493]
117958412  itgb3a; integrin beta-3a [KO:K06493]
117943574  proto-oncogene tyrosine-protein kinase Src-like isoform X1 [KO:K05704] [EC:2.7.10.2]
117947225  src; proto-oncogene tyrosine-protein kinase Src isoform X1 [KO:K05704] [EC:2.7.10.2]
117959692  syk; tyrosine-protein kinase SYK [KO:K05855] [EC:2.7.10.2]
117941351  caspase recruitment domain-containing protein 9-like [KO:K12794]
117937301  irf3; interferon regulatory factor 3 isoform X1 [KO:K05411]
117962210  tp53; cellular tumor antigen p53 [KO:K04451]
117944825  c5; complement C5 isoform X1 [KO:K03994]
117962114  LOW QUALITY PROTEIN: toll-like receptor 2 type-2 [KO:K10159]
117945977  tlr18; toll-like receptor 18 [KO:K10159]
117937605  myd88; myeloid differentiation primary response protein MyD88 [KO:K04729]
117949266  irf7; interferon regulatory factor 7 [KO:K09447]
117954573  tlr3; toll-like receptor 3 isoform X1 [KO:K05401]
117954779  ticam1; TIR domain-containing adapter molecule 1 [KO:K05842]
117949437  irak4; interleukin-1 receptor-associated kinase 4 isoform X1 [KO:K04733] [EC:2.7.11.1]
117948342  traf6; TNF receptor-associated factor 6 isoform X1 [KO:K03175] [EC:2.3.2.27]
117935477  mitogen-activated protein kinase kinase kinase 7-like [KO:K04427] [EC:2.7.11.25]
117961374  map3k7; mitogen-activated protein kinase kinase kinase 7 isoform X1 [KO:K04427] [EC:2.7.11.25]
117952378  tab1; TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 isoform X1 [KO:K04403]
117961933  tab2; TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 isoform X1 [KO:K04404]
117944585  interleukin-1 beta-like [KO:K04519]
117956362  il6; interleukin-6 [KO:K05405]
117957260  tumor necrosis factor-like [KO:K03156]
117942332  il12a; interleukin-12 subunit alpha [KO:K05406]
117954544  interleukin-12 subunit alpha-like [KO:K05406]
117956129  il12bb; interleukin-12 subunit beta isoform X1 [KO:K05425]
117945492  si:dkey-88e18.2; interleukin-12 subunit beta [KO:K05425]
117951870  il12ba; interleukin 12Ba isoform X1 [KO:K05425]
117953458  ifih1; interferon-induced helicase C domain-containing protein 1 [KO:K12647] [EC:5.6.2.6]
117935773  protein transport protein SEC31-like [KO:K12648]
117940992  LOW QUALITY PROTEIN: TNF receptor-associated factor 3-like [KO:K03174]
117943776  ikbke; inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform X1 [KO:K07211] [EC:2.7.11.10]
117936743  ifnphi4; interferon phi 4 [KO:K05414]
117940493  interferon a3-like [KO:K05414]
117956958  LOW QUALITY PROTEIN: cyclic GMP-AMP synthase [KO:K17834] [EC:2.7.7.86]
117960151  cgas; cyclic GMP-AMP synthase isoform X1 [KO:K17834] [EC:2.7.7.86]
117952059  sting1; stimulator of interferon genes protein isoform X1 [KO:K12654]
117961634  serine/threonine-protein phosphatase PP1-beta catalytic subunit-like [KO:K06269] [EC:3.1.3.16]
117934824  serine/threonine-protein phosphatase PP1-beta catalytic subunit [KO:K06269] [EC:3.1.3.16]
117936151  serine/threonine-protein phosphatase PP1-beta catalytic subunit-like [KO:K06269] [EC:3.1.3.16]
117944293  ppp1cc; serine/threonine-protein phosphatase PP1-gamma catalytic subunit A [KO:K06269] [EC:3.1.3.16]
117957592  ppp1caa; protein phosphatase 1, catalytic subunit, alpha isozyme a [KO:K06269] [EC:3.1.3.16]
117937322  ppp1cab; protein phosphatase 1, catalytic subunit, alpha isozyme b [KO:K06269] [EC:3.1.3.16]
117937035  eif2ak1; eukaryotic translation initiation factor 2-alpha kinase 1 isoform X1 [KO:K16194] [EC:2.7.11.1]
117960114  interferon-induced, double-stranded RNA-activated protein kinase-like isoform X1 [KO:K16195] [EC:2.7.11.1]
117960115  eukaryotic translation initiation factor 2-alpha kinase 3-like [KO:K16195] [EC:2.7.11.1]
117960116  eif2ak2; interferon-induced, double-stranded RNA-activated protein kinase [KO:K16195] [EC:2.7.11.1]
117960117  interferon-induced, double-stranded RNA-activated protein kinase-like [KO:K16195] [EC:2.7.11.1]
117936371  eif2ak3; eukaryotic translation initiation factor 2-alpha kinase 3 [KO:K08860] [EC:2.7.11.1]
117935379  eif2ak4; eIF-2-alpha kinase GCN2 [KO:K16196] [EC:2.7.11.1]
117961920  eif2s1b; eukaryotic translation initiation factor 2 subunit 1b [KO:K03237]
117959181  eif2b1; translation initiation factor eIF-2B subunit alpha [KO:K03239]
117961722  eif2b2; translation initiation factor eIF-2B subunit beta [KO:K03754]
117954506  eif2b3; translation initiation factor eIF-2B subunit gamma [KO:K03241]
117961397  eif2b4; translation initiation factor eIF-2B subunit delta isoform X1 [KO:K03680]
117953785  eif2b5; translation initiation factor eIF-2B subunit epsilon [KO:K03240]
117942906  hcfc1a; LOW QUALITY PROTEIN: host cell factor 1a [KO:K14966]
117938619  hcfc2; host cell factor 2 isoform X1 [KO:K27390]
117955766  pou2f3; POU domain, class 2, transcription factor 3 [KO:K09364]
117956668  POU domain, class 2, transcription factor 1 isoform X1 [KO:K09364]
117946206  pou2f2a; POU domain, class 2, transcription factor 2 isoform X1 [KO:K09364]
117953350  pou2f1b; POU domain, class 2, transcription factor 1b isoform X1 [KO:K09364]
117952422  crfb2; LOW QUALITY PROTEIN: cytokine receptor family member b2 [KO:K05131]
117936464  socs3b; suppressor of cytokine signaling 3b [KO:K04696]
117958510  socs3a; suppressor of cytokine signaling 3a [KO:K04696]
117950246  jak1; tyrosine-protein kinase JAK1 isoform X1 [KO:K11217] [EC:2.7.10.2]
117957661  tyk2; non-receptor tyrosine-protein kinase TYK2 [KO:K11219] [EC:2.7.10.2]
117953178  LOW QUALITY PROTEIN: signal transducer and activator of transcription 1-alpha/beta-like [KO:K11220]
117939468  stat1a; signal transducer and activator of transcription 1a isoform X1 [KO:K11220]
117943306  stat2; signal transducer and activator of transcription 2 isoform X1 [KO:K11221]
117938059  irf9; interferon regulatory factor 9 isoform X1 [KO:K04693]
117942369  si:dkey-182i3.10; zinc finger protein 850 [KO:K09228]
117942692  zinc finger protein 239-like [KO:K09228]
117935163  zinc finger protein 235-like [KO:K09228]
117943181  gastrula zinc finger protein XlCGF57.1-like [KO:K09228]
117949720  zinc finger protein OZF-like isoform X1 [KO:K09228]
117949734  zinc finger and SCAN domain-containing protein 22-like isoform X1 [KO:K09228]
117949742  zinc finger protein 90-like isoform X1 [KO:K09228]
117949749  gastrula zinc finger protein XlCGF57.1-like [KO:K09228]
117956467  zinc finger protein 484-like [KO:K09228]
117956475  gastrula zinc finger protein XlCGF26.1-like isoform X1 [KO:K09228]
117956476  gastrula zinc finger protein XlCGF57.1-like isoform X1 [KO:K09228]
117956478  zinc finger protein 32-like [KO:K09228]
117956479  zinc finger protein 2 homolog isoform X1 [KO:K09228]
117956484  zinc finger protein 467-like isoform X1 [KO:K09228]
117956504  zinc finger protein 37 homolog [KO:K09228]
117956547  zinc finger protein 271-like isoform X1 [KO:K09228]
117936629  zinc finger protein 135-like [KO:K09228]
117936630  zinc finger protein 572-like [KO:K09228]
117944619  zinc finger protein OZF-like isoform X1 [KO:K09228]
117944644  gastrula zinc finger protein XlCGF57.1-like isoform X1 [KO:K09228]
117944647  B-cell CLL/lymphoma 6 member B protein-like isoform X1 [KO:K09228]
117937232  zinc finger protein 572-like [KO:K09228]
117937358  oocyte zinc finger protein XlCOF6.1-like isoform X1 [KO:K09228]
117945425  zinc finger protein 184-like isoform X1 [KO:K09228]
117945627  gastrula zinc finger protein XlCGF57.1 [KO:K09228]
117945802  zinc finger protein 814-like [KO:K09228]
117958645  zinc finger protein 436-like [KO:K09228]
117938268  zinc finger protein 239-like [KO:K09228]
117952414  zinc finger protein 239-like [KO:K09228]
117938587  zinc finger protein 420-like [KO:K09228]
117938609  zinc finger protein 250-like isoform X1 [KO:K09228]
117938725  zinc finger protein 11-like [KO:K09228]
117952741  zinc finger protein 335-like isoform X1 [KO:K09228]
117952834  zinc finger protein 271-like [KO:K09228]
117938813  zinc finger protein ZFMSA12A-like isoform X1 [KO:K09228]
117938923  zinc finger protein 2 homolog [KO:K09228]
117946892  im:7147486; zinc finger protein 836 [KO:K09228]
117946903  si:dkeyp-84f3.5; zinc finger protein 208 [KO:K09228]
117959592  oocyte zinc finger protein XlCOF6-like isoform X1 [KO:K09228]
117959971  zinc finger protein 484-like [KO:K09228]
117939487  gastrula zinc finger protein XlCGF57.1-like isoform X1 [KO:K09228]
117939491  gastrula zinc finger protein XlCGF57.1-like isoform X1 [KO:K09228]
117939505  zinc finger protein 501-like isoform X1 [KO:K09228]
117939510  zinc finger protein 664-like [KO:K09228]
117939511  zinc finger protein 771-like [KO:K09228]
117939522  gastrula zinc finger protein XlCGF7.1-like [KO:K09228]
117953635  gastrula zinc finger protein XlCGF57.1-like isoform X1 [KO:K09228]
117953780  zinc finger protein 665-like [KO:K09228]
117953782  zinc finger protein ZFMSA12A-like [KO:K09228]
117939833  zinc finger protein 497-like [KO:K09228]
117940106  zinc finger and SCAN domain-containing protein 2-like [KO:K09228]
117940107  zinc finger and SCAN domain-containing protein 2-like [KO:K09228]
117940643  zinc finger protein 2-like [KO:K09228]
117947698  zinc finger protein OZF-like isoform X1 [KO:K09228]
117947700  zinc finger protein 391-like [KO:K09228]
117941483  gastrula zinc finger protein XlCGF17.1-like [KO:K09228]
117941882  oocyte zinc finger protein XlCOF6-like [KO:K09228]
117949578  zinc finger protein 239-like isoform X1 [KO:K09228]
117957916  gastrula zinc finger protein XlCGF26.1-like [KO:K09228]
117935024  zinc finger protein 239-like [KO:K09228]
117960046  ifngr1l; interferon gamma receptor 1-like isoform X1 [KO:K05132]
117952104  ifngr1; interferon gamma receptor 1 [KO:K05132]
117944332  jak2b; tyrosine-protein kinase JAK2 [KO:K04447] [EC:2.7.10.2]
117959539  jak2a; tyrosine-protein kinase JAK2a isoform X1 [KO:K04447] [EC:2.7.10.2]
117956851  daxx; death domain-associated protein 6 [KO:K02308]
117945671  tap1; antigen peptide transporter 1 [KO:K05653] [EC:7.4.2.14]
117956712  tap2a; antigen peptide transporter 2a [KO:K05654] [EC:7.4.2.14]
117936512  tap2t; antigen peptide transporter 2 [KO:K05654] [EC:7.4.2.14]
117956853  tapbp.1; TAP binding protein (tapasin), tandem duplicate 1 [KO:K08058]
117948534  pdia3; protein disulfide-isomerase A3 [KO:K08056] [EC:5.3.4.1]
117950568  calreticulin-like [KO:K08057]
117951123  calr; calreticulin [KO:K08057]
117954521  calreticulin-like [KO:K08057]
117957034  fibronectin type III domain-containing protein 1-like isoform X1 [KO:K06751]
117957213  saoe class I histocompatibility antigen, A alpha chain-like [KO:K06751]
117941490  major histocompatibility complex class I-related gene protein-like [KO:K06751]
117938548  beta-2-microglobulin-like [KO:K08055]
117938549  beta-2-microglobulin-like [KO:K08055]
117943653  HLA class II histocompatibility antigen, DQ beta 1 chain-like isoform X1 [KO:K06752]
117943654  rano class II histocompatibility antigen, B alpha chain-like [KO:K06752]
117945682  H-2 class II histocompatibility antigen, E-S beta chain-like [KO:K06752]
117945683  H-2 class II histocompatibility antigen, A-U alpha chain-like isoform X1 [KO:K06752]
117951180  cd74a; CD74 molecule, major histocompatibility complex, class II invariant chain a isoform X1 [KO:K06505]
117950011  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform-like [KO:K00922] [EC:2.7.1.153]
117940919  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform-like [KO:K00922] [EC:2.7.1.153]
117947614  pik3cd; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
117954189  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
117941822  pik3cb; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
117950300  phosphatidylinositol 3-kinase regulatory subunit gamma-like isoform X1 [KO:K02649]
117950796  pik3r3b; phosphoinositide-3-kinase, regulatory subunit 3b (gamma) [KO:K02649]
117944918  phosphatidylinositol 3-kinase regulatory subunit alpha-like isoform X1 [KO:K02649]
117959815  pik3r1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
117953620  pik3r2; phosphatidylinositol 3-kinase regulatory subunit beta isoform X1 [KO:K02649]
117954000  phosphatidylinositol 3-kinase regulatory subunit gamma-like [KO:K02649]
117934639  akt3b; RAC-gamma serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
117955971  RAC-beta serine/threonine-protein kinase-like [KO:K04456] [EC:2.7.11.1]
117936379  akt1; RAC-alpha serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
117959968  akt3a; RAC-gamma serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
117941951  akt2; RAC-beta serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
117944830  tsc1a; TSC complex subunit 1a isoform X1 [KO:K07206]
117959348  tsc1b; TSC complex subunit 1b [KO:K07206]
117958819  tsc2; tuberin isoform X1 [KO:K07207]
117944078  rhebl1; ras homolog, mTORC1 binding like 1 [KO:K07208]
117954566  rheb; GTP-binding protein Rheb [KO:K07208]
117947276  mtor; serine/threonine-protein kinase mTOR isoform X1 [KO:K07203] [EC:2.7.11.1]
117945052  eukaryotic translation initiation factor 4E-binding protein 1-like [KO:K07205]
117959637  eukaryotic translation initiation factor 4E-binding protein 2-like [KO:K07205]
117943737  srpk1b; SRSF protein kinase 1b isoform X1 [KO:K15409] [EC:2.7.11.1]
117947166  srpk1a; SRSF protein kinase 1a isoform X1 [KO:K15409] [EC:2.7.11.1]
117955181  serine/arginine-rich splicing factor 1 [KO:K12890]
117941848  srsf1a; serine/arginine-rich splicing factor 1A [KO:K12890]
117936466  srsf2a; serine and arginine rich splicing factor 2a [KO:K12891]
117958498  srsf2b; serine/arginine-rich splicing factor 2b isoform X1 [KO:K12891]
117943611  srsf3a; serine/arginine-rich splicing factor 3a [KO:K12892]
117943760  serine/arginine-rich splicing factor 3 [KO:K12892]
117961762  srsf5b; serine and arginine rich splicing factor 5b [KO:K12893]
117935424  srsf5a; serine and arginine rich splicing factor 5a isoform X1 [KO:K12893]
117956617  srsf4; serine/arginine-rich splicing factor 4 [KO:K12893]
117947695  serine/arginine-rich splicing factor 6-like [KO:K12893]
117941965  srsf7a; serine and arginine rich splicing factor 7a isoform X1 [KO:K12896]
117959336  srsf9; serine/arginine-rich splicing factor 9 [KO:K21123]
117951649  zgc:153681; nuclear RNA export factor 1 isoform X1 [KO:K14284]
117956328  THO complex subunit 4-like [KO:K12881]
117957527  alyref; THO complex subunit 4 [KO:K12881]
117949987  faslg; tumor necrosis factor ligand superfamily member 6 [KO:K04389]
117951831  cd40lg; CD40 ligand [KO:K04389]
117960374  tumor necrosis factor receptor superfamily member 6-like [KO:K04390]
117946254  tnfrsf1a; tumor necrosis factor receptor superfamily member 1A isoform X1 [KO:K03158]
117947296  si:ch211-112c15.8; tumor necrosis factor receptor superfamily member 1A [KO:K03158]
117951222  tradd; tumor necrosis factor receptor type 1-associated DEATH domain protein [KO:K03171]
117942648  fadd; FAS-associated death domain protein [KO:K02373]
117953418  casp10; caspase-8 isoform X1 [KO:K04398] [EC:3.4.22.61]
117954805  casp8; caspase-8 [KO:K04398] [EC:3.4.22.61]
117954806  caspase-8-like [KO:K04398] [EC:3.4.22.61]
117949058  bida; BH3 interacting domain death agonist [KO:K04726]
117958554  apoptosis regulator BAX-like [KO:K02159]
117942138  zgc:153993; apoptosis regulator BAX [KO:K02159]
117957911  apoptosis regulator BAX-like isoform X1 [KO:K02159]
117934567  badb; BCL2 associated agonist of cell death b [KO:K02158]
117953749  bcl2b; apoptosis regulator Bcl-2 [KO:K02161]
117943312  bcl-2-like protein 1 [KO:K04570]
117947404  bcl2l1; bcl-2-like protein 1 [KO:K04570]
117953301  cytochrome c-like [KO:K08738]
117960327  cytochrome c [KO:K08738]
117938437  apaf1; apoptotic protease-activating factor 1 isoform X1 [KO:K02084]
117948337  casp9; caspase-9 isoform X1 [KO:K04399] [EC:3.4.22.62]
117951380  caspase-3-like isoform X1 [KO:K02187] [EC:3.4.22.56]
117960699  casp3a; caspase-3a [KO:K02187] [EC:3.4.22.56]
Compound
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C20640  Cyclic GMP-AMP
C20935  2-5A
Reference
PMID:12787566
  Authors
Granger SW, Rickert S
  Title
LIGHT-HVEM signaling and the regulation of T cell-mediated immunity.
  Journal
Cytokine Growth Factor Rev 14:289-96 (2003)
DOI:10.1016/S1359-6101(03)00031-5
Reference
PMID:19495760
  Authors
Steinberg MW, Shui JW, Ware CF, Kronenberg M
  Title
Regulating the mucosal immune system: the contrasting roles of LIGHT, HVEM, and their various partners.
  Journal
Semin Immunopathol 31:207-21 (2009)
DOI:10.1007/s00281-009-0157-4
Reference
PMID:20221426
  Authors
MacLeod IJ, Minson T
  Title
Binding of herpes simplex virus type-1 virions leads to the induction of intracellular signalling in the absence of virus entry.
  Journal
PLoS One 5:e9560 (2010)
DOI:10.1371/journal.pone.0009560
Reference
PMID:23150579
  Authors
Gianni T, Leoni V, Chesnokova LS, Hutt-Fletcher LM, Campadelli-Fiume G
  Title
alphavbeta3-integrin is a major sensor and activator of innate immunity to herpes simplex virus-1.
  Journal
Proc Natl Acad Sci U S A 109:19792-7 (2012)
DOI:10.1073/pnas.1212597109
Reference
PMID:25375272
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Related
pathway
ecra03040  Spliceosome
ecra03050  Proteasome
ecra04115  p53 signaling pathway
ecra04210  Apoptosis
ecra04620  Toll-like receptor signaling pathway
ecra04622  RIG-I-like receptor signaling pathway
KO pathway
ko05168   
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