KEGG   PATHWAY: tge05168
Entry
tge05168                    Pathway                                
Name
Herpes simplex virus 1 infection - Theropithecus gelada (gelada)
Description
Herpes simplex virus 1(HSV-1) is a common human pathogen, which initially infects orofacial mucosal surfaces. The virus replicates in epithelial cells at these sites, causing clinically overt disease characterized by vesicular lesions. HSV-1 then penetrates to the nervous system and establishes latency in sensory neurons. Throughout the lifetime of the host, HSV-1 may reactivate from its latent state and reinitiate a lytic infection cycle. HSV-1 has developed various mechanisms to escape its host innate immune responses and increased its capacity to replicate and to persist. ICP34.5, ICP0, ICP27, Us11 and Vhs (UL41) are the proteins involved in viral interference.
Class
Human Diseases; Infectious disease: viral
Pathway map
tge05168  Herpes simplex virus 1 infection
tge05168

Organism
Theropithecus gelada (gelada) [GN:tge]
Gene
112623174  LTA; lymphotoxin-alpha [KO:K05468]
112613108  TNFSF14; tumor necrosis factor ligand superfamily member 14 isoform X1 [KO:K05477]
112617618  TNFRSF14; tumor necrosis factor receptor superfamily member 14 [KO:K05152]
112608018  TRAF2; TNF receptor-associated factor 2 [KO:K03173] [EC:2.3.2.27]
112610017  TRAF5; TNF receptor-associated factor 5 isoform X1 [KO:K09849]
112629970  IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1 [KO:K07209] [EC:2.7.11.10]
112632013  CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1 [KO:K04467] [EC:2.7.11.10]
112616513  IKBKG; NF-kappa-B essential modulator isoform X1 [KO:K07210]
112616847  NF-kappa-B essential modulator-like [KO:K07210]
112628601  NFKBIA; NF-kappa-B inhibitor alpha [KO:K04734]
112624752  NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1 [KO:K02580]
112605794  RELA; transcription factor p65 isoform X1 [KO:K04735]
112605791  BIRC2; baculoviral IAP repeat-containing protein 2 isoform X1 [KO:K16060]
112605792  BIRC3; baculoviral IAP repeat-containing protein 3 [KO:K16060]
112609760  CCL2; C-C motif chemokine 2 [KO:K14624]
112606895  NECTIN1; nectin-1 isoform X1 [KO:K06081]
112612476  NECTIN2; nectin-2 isoform X1 [KO:K06531]
112621400  paired immunoglobulin-like type 2 receptor alpha isoform X1 [KO:K15411]
112635452  PTPN11; tyrosine-protein phosphatase non-receptor type 11 isoform X1 [KO:K07293] [EC:3.1.3.48]
112633971  ITGA5; integrin alpha-5 [KO:K06484]
112609798  ITGB3; integrin beta-3 isoform X1 [KO:K06493]
112633533  SRC; proto-oncogene tyrosine-protein kinase Src [KO:K05704] [EC:2.7.10.2]
112608327  SYK; tyrosine-protein kinase SYK isoform X1 [KO:K05855] [EC:2.7.10.2]
112608008  CARD9; caspase recruitment domain-containing protein 9 isoform X1 [KO:K12794]
112612899  IRF3; interferon regulatory factor 3 isoform X1 [KO:K05411]
112608413  IFNB1; interferon beta [KO:K05415]
112610199  TP53; cellular tumor antigen p53 isoform X1 [KO:K04451]
112612406  C3; complement C3 [KO:K03990]
112607645  C5; complement C5 isoform X1 [KO:K03994]
112615729  CFP; properdin [KO:K15412]
112624698  TLR2; toll-like receptor 2 [KO:K10159]
112619672  TLR9; toll-like receptor 9 [KO:K10161]
112618384  MYD88; myeloid differentiation primary response protein MyD88 isoform X1 [KO:K04729]
112606379  IRF7; interferon regulatory factor 7 isoform X1 [KO:K09447]
112625447  TLR3; toll-like receptor 3 [KO:K05401]
112613598  TICAM1; TIR domain-containing adapter molecule 1 [KO:K05842]
112617260  interleukin-1 receptor-associated kinase 4 [KO:K04733] [EC:2.7.11.1]
112617282  interleukin-1 receptor-associated kinase 4 [KO:K04733] [EC:2.7.11.1]
112615074  IRAK1; interleukin-1 receptor-associated kinase 1 isoform X1 [KO:K04730] [EC:2.7.11.1]
112607412  TRAF6; TNF receptor-associated factor 6 [KO:K03175] [EC:2.3.2.27]
112622899  MAP3K7; mitogen-activated protein kinase kinase kinase 7 isoform X1 [KO:K04427] [EC:2.7.11.25]
112633811  TAB1; TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 isoform X1 [KO:K04403]
112622975  TAB2; TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 [KO:K04404]
112604696  IL1B; interleukin-1 beta isoform X1 [KO:K04519]
112609075  CCL5; C-C motif chemokine 5 [KO:K12499]
112621592  IL6; interleukin-6 isoform X1 [KO:K05405]
112622917  TNF; tumor necrosis factor [KO:K03156]
112619066  IL12A; interleukin-12 subunit alpha isoform X1 [KO:K05406]
112626411  IL12B; interleukin-12 subunit beta [KO:K05425]
112607797  DDX58; probable ATP-dependent RNA helicase DDX58 isoform X1 [KO:K12646] [EC:5.6.2.6]
112636165  IFIH1; interferon-induced helicase C domain-containing protein 1 [KO:K12647] [EC:5.6.2.6]
112632848  MAVS; mitochondrial antiviral-signaling protein isoform X1 [KO:K12648]
112629252  TRAF3; TNF receptor-associated factor 3 isoform X1 [KO:K03174]
112606745  IKBKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform X1 [KO:K07211] [EC:2.7.11.10]
112635245  TBK1; serine/threonine-protein kinase TBK1 [KO:K05410] [EC:2.7.11.10]
112608216  interferon alpha-17 [KO:K05414]
112608221  IFNA21; interferon alpha-21 [KO:K05414]
112608232  interferon alpha-10 [KO:K05414]
112608255  interferon alpha-2 [KO:K05414]
112608259  interferon alpha-14 [KO:K05414]
112608273  interferon alpha-1/13 [KO:K05414]
112608278  LOW QUALITY PROTEIN: interferon alpha-6-like [KO:K05414]
112608298  interferon alpha-8 [KO:K05414]
112617922  interferon alpha-1/13-like [KO:K05414]
112622071  CGAS; cyclic GMP-AMP synthase [KO:K17834] [EC:2.7.7.86]
112626617  TMEM173; stimulator of interferon genes protein [KO:K12654]
112606994  PPP1CA; serine/threonine-protein phosphatase PP1-alpha catalytic subunit isoform X1 [KO:K06269] [EC:3.1.3.16]
112636950  PPP1CB; serine/threonine-protein phosphatase PP1-beta catalytic subunit isoform X1 [KO:K06269] [EC:3.1.3.16]
112604670  serine/threonine-protein phosphatase PP1-gamma catalytic subunit [KO:K06269] [EC:3.1.3.16]
112634287  PPP1CC; serine/threonine-protein phosphatase PP1-gamma catalytic subunit [KO:K06269] [EC:3.1.3.16]
112621777  EIF2AK1; eukaryotic translation initiation factor 2-alpha kinase 1 isoform X1 [KO:K16194] [EC:2.7.11.1]
112605212  EIF2AK2; interferon-induced, double-stranded RNA-activated protein kinase isoform X1 [KO:K16195] [EC:2.7.11.1]
112605118  EIF2AK3; eukaryotic translation initiation factor 2-alpha kinase 3 isoform X1 [KO:K08860] [EC:2.7.11.1]
112627816  EIF2AK4; eIF-2-alpha kinase GCN2 [KO:K16196] [EC:2.7.11.1]
112629021  EIF2S1; eukaryotic translation initiation factor 2 subunit 1 [KO:K03237]
112633998  EIF2B1; translation initiation factor eIF-2B subunit alpha isoform X1 [KO:K03239]
112629259  EIF2B2; translation initiation factor eIF-2B subunit beta [KO:K03754]
112636275  EIF2B3; translation initiation factor eIF-2B subunit gamma isoform X1 [KO:K03241]
112636930  EIF2B4; translation initiation factor eIF-2B subunit delta isoform X1 [KO:K03680]
112618280  EIF2B5; translation initiation factor eIF-2B subunit epsilon isoform X1 [KO:K03240]
112634074  OAS3; 2'-5'-oligoadenylate synthase 3 [KO:K14216] [EC:2.7.7.84]
112634075  OAS2; 2'-5'-oligoadenylate synthase 2 [KO:K14216] [EC:2.7.7.84]
112634076  OAS1; 2'-5'-oligoadenylate synthase 1 isoform X1 [KO:K14216] [EC:2.7.7.84]
112631975  RNASEL; 2-5A-dependent ribonuclease [KO:K01165]
112615066  HCFC1; host cell factor 1 isoform X1 [KO:K14966]
112635324  HCFC2; host cell factor 2 [KO:K27390]
112606519  POU2F3; POU domain, class 2, transcription factor 3 isoform X1 [KO:K09364]
112622584  POU2F1; POU domain, class 2, transcription factor 1 isoform X1 [KO:K09364]
112612109  POU2F2; POU domain, class 2, transcription factor 2 isoform X1 [KO:K09364]
112620838  IFNAR1; interferon alpha/beta receptor 1 isoform X1 [KO:K05130]
112620495  IFNAR2; interferon alpha/beta receptor 2 isoform X1 [KO:K05131]
112610241  SOCS3; suppressor of cytokine signaling 3 [KO:K04696]
112620491  JAK1; tyrosine-protein kinase JAK1 isoform X1 [KO:K11217] [EC:2.7.10.2]
112613284  TYK2; non-receptor tyrosine-protein kinase TYK2 [KO:K11219] [EC:2.7.10.2]
112635950  STAT1; signal transducer and activator of transcription 1-alpha/beta isoform X1 [KO:K11220]
112634334  STAT2; signal transducer and activator of transcription 2 isoform X1 [KO:K11221]
112629242  IRF9; interferon regulatory factor 9 [KO:K04693]
112606334  ZNF195; zinc finger protein 195 isoform X1 [KO:K09228]
112606390  ZNF214; zinc finger protein 214 isoform X1 [KO:K09228]
112612616  zinc finger protein 845 isoform X1 [KO:K09228]
112612639  ZNF615; zinc finger protein 615 isoform X1 [KO:K09228]
112612657  ZNF749; zinc finger protein 749 isoform X1 [KO:K09228]
112612659  zinc finger protein 772 isoform X1 [KO:K09228]
112612689  ZNF667; zinc finger protein 667 isoform X1 [KO:K09228]
112612697  ZNF846; zinc finger protein 846 isoform X1 [KO:K09228]
112612706  ZNF543; zinc finger protein 543 isoform X1 [KO:K09228]
112612710  ZNF614; zinc finger protein 614 [KO:K09228]
112612713  ZNF175; zinc finger protein 175 [KO:K09228]
112612716  ZFP82; zinc finger protein 82 homolog isoform X1 [KO:K09228]
112612726  ZNF304; LOW QUALITY PROTEIN: zinc finger protein 304 [KO:K09228]
112612733  ZNF471; zinc finger protein 471 isoform X1 [KO:K09228]
112612738  ZNF14; zinc finger protein 14 [KO:K09228]
112612741  ZNF181; zinc finger protein 181 isoform X1 [KO:K09228]
112612742  ZNF302; zinc finger protein 302 isoform X1 [KO:K09228]
112612744  ZNF613; zinc finger protein 613 isoform X1 [KO:K09228]
112612754  ZNF562; zinc finger protein 562 [KO:K09228]
112612756  LOW QUALITY PROTEIN: zinc finger protein 433-like [KO:K09228]
112612759  ZNF878; zinc finger protein 878 [KO:K09228]
112612793  ZNF792; zinc finger protein 792 [KO:K09228]
112612808  ZNF556; zinc finger protein 556 [KO:K09228]
112612811  ZNF460; zinc finger protein 460 isoform X1 [KO:K09228]
112612815  LOW QUALITY PROTEIN: zinc finger protein 208-like [KO:K09228]
112612816  LOW QUALITY PROTEIN: zinc finger protein 43-like [KO:K09228]
112612817  LOW QUALITY PROTEIN: zinc finger protein 724-like [KO:K09228]
112612818  LOW QUALITY PROTEIN: zinc finger protein 85-like [KO:K09228]
112612819  ZNF738; protein ZNF738 isoform X1 [KO:K09228]
112612820  LOW QUALITY PROTEIN: zinc finger protein 100-like [KO:K09228]
112612821  zinc finger protein 676-like isoform X1 [KO:K09228]
112612822  zinc finger protein 93-like [KO:K09228]
112612823  ZNF257; zinc finger protein 257 isoform X1 [KO:K09228]
112612824  LOW QUALITY PROTEIN: zinc finger protein 714-like [KO:K09228]
112612826  LOW QUALITY PROTEIN: zinc finger protein 737-like [KO:K09228]
112612827  LOW QUALITY PROTEIN: zinc finger protein 431-like [KO:K09228]
112612828  zinc finger protein 253-like isoform X1 [KO:K09228]
112612829  ZNF682; zinc finger protein 682 isoform X1 [KO:K09228]
112612830  LOW QUALITY PROTEIN: zinc finger protein 506-like [KO:K09228]
112612839  zinc finger protein 737-like [KO:K09228]
112612886  ZNF77; zinc finger protein 77 [KO:K09228]
112612891  ZNF557; zinc finger protein 557 [KO:K09228]
112612893  ZNF101; zinc finger protein 101 isoform X1 [KO:K09228]
112612910  ZNF573; zinc finger protein 573 isoform X1 [KO:K09228]
112612915  ZNF709; zinc finger protein 709 [KO:K09228]
112612938  zinc finger protein 324A [KO:K09228]
112612939  ZNF324B; LOW QUALITY PROTEIN: zinc finger protein 324B [KO:K09228]
112612959  ZNF554; zinc finger protein 554 [KO:K09228]
112612963  ZNF132; zinc finger protein 132 isoform X1 [KO:K09228]
112612969  zinc finger protein 816-like isoform X1 [KO:K09228]
112612983  ZNF317; zinc finger protein 317 isoform X1 [KO:K09228]
112620576  LOW QUALITY PROTEIN: zinc finger protein 716-like [KO:K09228]
112620614  ZNF777; zinc finger protein 777 isoform X1 [KO:K09228]
112620615  ZNF746; zinc finger protein 746 isoform X1 [KO:K09228]
112620654  zinc finger protein 680-like isoform X1 [KO:K09228]
112620800  ZNF736; zinc finger protein 736 [KO:K09228]
112634977  ZNF605; zinc finger protein 605 [KO:K09228]
112634979  zinc finger protein 239-like [KO:K09228]
112635414  ZNF84; zinc finger protein 84 [KO:K09228]
112612992  zinc finger protein 850 isoform X1 [KO:K09228]
112612994  ZNF585A; zinc finger protein 585A isoform X1 [KO:K09228]
112612995  ZNF585B; zinc finger protein 585B isoform X1 [KO:K09228]
112612996  ZNF420; zinc finger protein 420 isoform X1 [KO:K09228]
112612997  ZNF568; zinc finger protein 568 isoform X1 [KO:K09228]
112612998  HKR1; Krueppel-related zinc finger protein 1 isoform X1 [KO:K09228]
112612999  ZNF567; zinc finger protein 567 isoform X1 [KO:K09228]
112613000  ZNF790; zinc finger protein 790 [KO:K09228]
112613001  ZNF527; zinc finger protein 527 isoform X1 [KO:K09228]
112613003  ZNF383; zinc finger protein 383 isoform X1 [KO:K09228]
112613004  ZNF829; zinc finger protein 829 isoform X1 [KO:K09228]
112613012  ZNF530; zinc finger protein 530 isoform X1 [KO:K09228]
112613054  ZNF30; zinc finger protein 30 isoform X1 [KO:K09228]
112613089  ZFP28; zinc finger protein 28 homolog [KO:K09228]
112613090  ZNF470; zinc finger protein 470 [KO:K09228]
112613094  ZNF114; zinc finger protein 114 isoform X1 [KO:K09228]
112613111  zinc finger protein 211 isoform X1 [KO:K09228]
112613116  ZNF559; zinc finger protein 559 isoform X1 [KO:K09228]
112613118  ZNF177; zinc finger protein 177 isoform X1 [KO:K09228]
112613123  ZNF529; zinc finger protein 529 isoform X1 [KO:K09228]
112613124  ZNF382; zinc finger protein 382 isoform X1 [KO:K09228]
112613174  zinc finger protein 560 isoform X1 [KO:K09228]
112613175  ZNF426; zinc finger protein 426 isoform X1 [KO:K09228]
112613177  ZNF561; zinc finger protein 561 isoform X1 [KO:K09228]
112613178  LOW QUALITY PROTEIN: zinc finger protein 562-like [KO:K09228]
112613184  ZNF17; zinc finger protein 17 isoform X1 [KO:K09228]
112613185  zinc finger protein 548 isoform X1 [KO:K09228]
112613187  ZNF547; zinc finger protein 547 [KO:K09228]
112613196  ZNF699; zinc finger protein 699 [KO:K09228]
112613201  ZNF791; zinc finger protein 791 isoform X1 [KO:K09228]
112613213  ZNF780A; LOW QUALITY PROTEIN: zinc finger protein 780A [KO:K09228]
112613214  zinc finger protein 780B [KO:K09228]
112613249  ZNF649; zinc finger protein 649 isoform X1 [KO:K09228]
112613250  ZNF577; zinc finger protein 577 [KO:K09228]
112613283  ZNF490; zinc finger protein 490 isoform X1 [KO:K09228]
112613288  ZNF565; zinc finger protein 565 isoform X1 [KO:K09228]
112620905  ZNF786; zinc finger protein 786 isoform X1 [KO:K09228]
112621023  ZNF853; zinc finger protein 853 [KO:K09228]
112621084  zinc finger protein 107-like isoform X1 [KO:K09228]
112621086  LOW QUALITY PROTEIN: zinc finger protein 85-like [KO:K09228]
112621211  zinc finger protein 679 [KO:K09228]
112635564  ZNF695; zinc finger protein 695 [KO:K09228]
112635740  ZFP69; zinc finger protein ZFP69 isoform X1 [KO:K09228]
112613370  ZNF583; zinc finger protein 583 isoform X1 [KO:K09228]
112613371  ZNF582; zinc finger protein 582 isoform X1 [KO:K09228]
112613373  zinc finger protein OZF-like isoform X1 [KO:K09228]
112613384  ZNF805; zinc finger protein 805 [KO:K09228]
112613393  ZNF283; zinc finger protein 283 isoform X1 [KO:K09228]
112613394  zinc finger protein 404 [KO:K09228]
112613404  LOW QUALITY PROTEIN: zinc finger protein 544-like [KO:K09228]
112613406  ZNF8; zinc finger protein 8 [KO:K09228]
112613418  zinc finger protein 799 isoform X1 [KO:K09228]
112613419  ZNF563; zinc finger protein 563 isoform X1 [KO:K09228]
112613434  LOW QUALITY PROTEIN: zinc finger protein 761-like [KO:K09228]
112613506  zinc finger protein 808-like isoform X1 [KO:K09228]
112613507  LOW QUALITY PROTEIN: zinc finger protein 888-like [KO:K09228]
112613522  ZNF841; zinc finger protein 841 isoform X1 [KO:K09228]
112613523  ZNF432; zinc finger protein 432 [KO:K09228]
112613543  ZNF566; zinc finger protein 566 isoform X1 [KO:K09228]
112613548  ZNF44; zinc finger protein 44 isoform X1 [KO:K09228]
112613549  zinc finger protein 709-like [KO:K09228]
112613569  ZNF836; zinc finger protein 836 [KO:K09228]
112613570  ZNF616; zinc finger protein 616 [KO:K09228]
112613588  ZNF555; zinc finger protein 555 isoform X1 [KO:K09228]
112613589  ZNF57; zinc finger protein 57 isoform X1 [KO:K09228]
112613590  ZNF416; zinc finger protein 416 isoform X1 [KO:K09228]
112613591  ZIK1; zinc finger protein interacting with ribonucleoprotein K isoform X1 [KO:K09228]
112613609  ZNF564; zinc finger protein 564 isoform X1 [KO:K09228]
112613612  ZIM3; zinc finger imprinted 3 [KO:K09228]
112613613  ZNF234; zinc finger protein 234 isoform X1 [KO:K09228]
112613624  ZNF558; zinc finger protein 558 isoform X1 [KO:K09228]
112613630  ZNF226; zinc finger protein 226 isoform X1 [KO:K09228]
112621330  ZNF212; zinc finger protein 212 isoform X1 [KO:K09228]
112621349  LOW QUALITY PROTEIN: zinc finger protein 669-like [KO:K09228]
112621406  ZNF12; zinc finger protein 12 isoform X1 [KO:K09228]
112621439  ZNF282; zinc finger protein 282 [KO:K09228]
112621454  putative zinc finger protein 735 [KO:K09228]
112621509  ZNF398; zinc finger protein 398 isoform X1 [KO:K09228]
112621531  ZNF783; protein ZNF783 [KO:K09228]
112621609  LOW QUALITY PROTEIN: zinc finger protein 736-like [KO:K09228]
112621737  ZNF425; zinc finger protein 425 [KO:K09228]
112621780  ZNF316; zinc finger protein 316 [KO:K09228]
112613813  ZNF768; zinc finger protein 768 [KO:K09228]
112613814  ZNF689; zinc finger protein 689 [KO:K09228]
112613815  ZNF764; zinc finger protein 764 isoform X1 [KO:K09228]
112613818  ZNF688; zinc finger protein 688 isoform X1 [KO:K09228]
112613974  ZFP90; zinc finger protein 90 homolog isoform X1 [KO:K09228]
112629690  ZNF7; zinc finger protein 7 isoform X1 [KO:K09228]
112629691  ZNF250; zinc finger protein 250 isoform X1 [KO:K09228]
112629692  ZNF34; zinc finger protein 34 isoform X1 [KO:K09228]
112629693  ZNF517; zinc finger protein 517 isoform X1 [KO:K09228]
112607981  ZNF79; zinc finger protein 79 isoform X1 [KO:K09228]
112608028  ZNF658; zinc finger protein 658 isoform X1 [KO:K09228]
112608135  ZNF782; zinc finger protein 782 isoform X1 [KO:K09228]
112608145  ZFP37; zinc finger protein 37 homolog isoform X1 [KO:K09228]
112608261  ZNF484; zinc finger protein 484 isoform X1 [KO:K09228]
112614283  ZNF19; zinc finger protein 19 isoform X1 [KO:K09228]
112614291  ZNF778; zinc finger protein 778 isoform X1 [KO:K09228]
112614292  zinc finger protein 85-like isoform X1 [KO:K09228]
112614348  ZNF597; zinc finger protein 597 [KO:K09228]
112614468  ZSCAN32; zinc finger and SCAN domain-containing protein 32 isoform X1 [KO:K09228]
112630036  ZNF707; zinc finger protein 707 isoform X1 [KO:K09228]
112630224  ZNF596; zinc finger protein 596 [KO:K09228]
112608563  LOW QUALITY PROTEIN: zinc finger protein 669-like [KO:K09228]
112608622  ZNF169; zinc finger protein 169 isoform X1 [KO:K09228]
112608665  ZNF189; zinc finger protein 189 isoform X1 [KO:K09228]
112608743  ZNF510; zinc finger protein 510 isoform X1 [KO:K09228]
112614681  zinc finger protein 267 isoform X1 [KO:K09228]
112614693  ZFP1; zinc finger protein 1 homolog isoform X1 [KO:K09228]
112614764  ZNF200; zinc finger protein 200 [KO:K09228]
112614801  ZNF205; zinc finger protein 205 [KO:K09228]
112614840  ZNF23; zinc finger protein 23 isoform X1 [KO:K09228]
112614983  ZNF81; zinc finger protein 81 [KO:K09228]
112623080  ZNF184; zinc finger protein 184 isoform X1 [KO:K09228]
112623248  ZNF311; zinc finger protein 311 isoform X1 [KO:K09228]
112623411  ZFP57; zinc finger protein 57 homolog [KO:K09228]
112630543  zinc finger protein 252-like isoform X1 [KO:K09228]
112630657  ZNF705D; LOW QUALITY PROTEIN: zinc finger protein 705D [KO:K09228]
112630763  ZNF251; zinc finger protein 251 isoform X1 [KO:K09228]
112630777  ZNF623; zinc finger protein 623 [KO:K09228]
112631016  zinc finger protein 25-like [KO:K09228]
112631095  zinc finger protein 37A [KO:K09228]
112631096  LOW QUALITY PROTEIN: zinc finger protein 37A-like [KO:K09228]
112608950  ZNF286A; zinc finger protein 286A isoform X1 [KO:K09228]
112615666  ZNF182; zinc finger protein 182 isoform X1 [KO:K09228]
112615801  ZNF41; zinc finger protein 41 isoform X1 [KO:K09228]
112615806  ZNF674; zinc finger protein 674 isoform X1 [KO:K09228]
112615808  ZNF157; zinc finger protein 157 [KO:K09228]
112615935  ZNF630; zinc finger protein 630 isoform X1 [KO:K09228]
112624212  ZNF721; LOW QUALITY PROTEIN: zinc finger protein 721 [KO:K09228]
112624213  LOW QUALITY PROTEIN: zinc finger protein 141-like [KO:K09228]
112624214  ZNF718; LOW QUALITY PROTEIN: zinc finger protein 718 [KO:K09228]
112616421  ZNF275; zinc finger protein 275 [KO:K09228]
112616543  ZFP92; zinc finger protein 92 homolog [KO:K09228]
112624660  zinc finger protein 595 isoform X1 [KO:K09228]
112631824  ZNF248; zinc finger protein 248 isoform X1 [KO:K09228]
112631942  zinc finger protein 33B isoform X1 [KO:K09228]
112632044  ZNF25; zinc finger protein 25 isoform X1 [KO:K09228]
112616911  zinc finger protein 562 [KO:K09228]
112617052  zinc finger protein 436 [KO:K09228]
112617384  LOW QUALITY PROTEIN: zinc finger protein 669-like [KO:K09228]
112617453  zinc finger protein 436-like [KO:K09228]
112632104  ZNF33B; zinc finger protein 33B isoform X1 [KO:K09228]
112617639  zinc finger protein 669-like [KO:K09228]
112617840  zinc finger protein 669-like [KO:K09228]
112618312  LOW QUALITY PROTEIN: zinc finger protein 669-like [KO:K09228]
112625272  zinc finger protein 717-like [KO:K09228]
112633024  ZNF334; zinc finger protein 334 isoform X1 [KO:K09228]
112626200  ZNF454; zinc finger protein 454 [KO:K09228]
112633247  ZNF74; zinc finger protein 74 isoform X1 [KO:K09228]
112618785  ZNF860; LOW QUALITY PROTEIN: zinc finger protein 860 [KO:K09228]
112619015  ZNF619; zinc finger protein 619 isoform X1 [KO:K09228]
112626368  ZNF354B; zinc finger protein 354B [KO:K09228]
112633573  ZNF343; zinc finger protein 343 isoform X1 [KO:K09228]
112633665  ZNF133; zinc finger protein 133 isoform X1 [KO:K09228]
112604650  ZNF514; zinc finger protein 514 [KO:K09228]
112604651  ZNF2; zinc finger protein 2 isoform X1 [KO:K09228]
112611842  ZNF45; zinc finger protein 45 [KO:K09228]
112611844  zinc finger protein 20-like isoform X1 [KO:K09228]
112611845  ZNF700; zinc finger protein 700 isoform X1 [KO:K09228]
112611846  ZNF441; zinc finger protein 441 isoform X1 [KO:K09228]
112611847  ZNF823; zinc finger protein 823 isoform X1 [KO:K09228]
112611849  zinc finger protein 69 isoform X1 [KO:K09228]
112611850  zinc finger protein 136 isoform X1 [KO:K09228]
112611852  ZNF20; zinc finger protein 20 isoform X1 [KO:K09228]
112611853  zinc finger protein 440 isoform X1 [KO:K09228]
112611882  zinc finger protein 506-like [KO:K09228]
112611884  zinc finger protein 723-like [KO:K09228]
112611908  zinc finger protein 345-like [KO:K09228]
112611914  ZNF528; LOW QUALITY PROTEIN: zinc finger protein 528 [KO:K09228]
112611916  ZNF534; LOW QUALITY PROTEIN: zinc finger protein 534 [KO:K09228]
112611921  LOW QUALITY PROTEIN: zinc finger protein 765-like [KO:K09228]
112611974  ZNF546; zinc finger protein 546 [KO:K09228]
112611983  ZFP14; zinc finger protein 14 homolog [KO:K09228]
112611991  zinc finger protein 492-like [KO:K09228]
112611993  zinc finger protein 726-like [KO:K09228]
112612017  ZNF606; zinc finger protein 606 isoform X1 [KO:K09228]
112612020  ZNF135; zinc finger protein 135 isoform X1 [KO:K09228]
112612054  zinc finger protein 91-like isoform X1 [KO:K09228]
112612055  ZNF519; zinc finger protein 519 isoform X1 [KO:K09228]
112612057  zinc finger protein 726 isoform X1 [KO:K09228]
112612061  zinc finger protein 675 isoform X1 [KO:K09228]
112612062  zinc finger protein 492 isoform X1 [KO:K09228]
112612065  zinc finger protein 627 isoform X1 [KO:K09228]
112612071  LOW QUALITY PROTEIN: putative zinc finger protein 730 [KO:K09228]
112612167  ZNF224; zinc finger protein 224 isoform X1 [KO:K09228]
112612168  ZNF225; zinc finger protein 225 [KO:K09228]
112612169  zinc finger protein 155 isoform X1 [KO:K09228]
112612171  ZNF221; zinc finger protein 221 [KO:K09228]
112612172  ZNF284; zinc finger protein 284 isoform X1 [KO:K09228]
112612173  ZNF223; zinc finger protein 223 isoform X1 [KO:K09228]
112612174  ZNF222; zinc finger protein 222 isoform X1 [KO:K09228]
112612194  zinc finger protein 30 homolog isoform X1 [KO:K09228]
112612196  ZNF569; zinc finger protein 569 isoform X1 [KO:K09228]
112612197  ZNF607; zinc finger protein 607 isoform X1 [KO:K09228]
112612198  ZNF540; zinc finger protein 540 isoform X1 [KO:K09228]
112612199  zinc finger protein 570 isoform X1 [KO:K09228]
112612200  ZNF793; zinc finger protein 793 [KO:K09228]
112612225  ZNF112; zinc finger protein 112 isoform X1 [KO:K09228]
112612227  ZNF229; zinc finger protein 229 isoform X1 [KO:K09228]
112612228  ZNF227; zinc finger protein 227 isoform X1 [KO:K09228]
112612229  ZNF235; zinc finger protein 235 isoform X1 [KO:K09228]
112612230  ZNF233; LOW QUALITY PROTEIN: zinc finger protein 233 [KO:K09228]
112612231  ZNF549; zinc finger protein 549 isoform X1 [KO:K09228]
112612232  ZNF285; zinc finger protein 285 isoform X1 [KO:K09228]
112612233  zinc finger protein 550 [KO:K09228]
112612244  ZNF256; zinc finger protein 256 [KO:K09228]
112612246  ZNF418; zinc finger protein 418 [KO:K09228]
112612247  ZNF417; zinc finger protein 417 isoform X1 [KO:K09228]
112612248  zinc finger protein 587-like isoform X1 [KO:K09228]
112612249  zinc finger protein 552 isoform X1 [KO:K09228]
112619190  ZNF589; zinc finger protein 589 isoform X1 [KO:K09228]
112619348  ZNF662; zinc finger protein 662 [KO:K09228]
112626767  ZNF300; zinc finger protein 300 isoform X1 [KO:K09228]
112626839  LOW QUALITY PROTEIN: zinc finger protein 705A-like [KO:K09228]
112626892  ZNF879; zinc finger protein 879 [KO:K09228]
112626893  ZNF354C; zinc finger protein 354C [KO:K09228]
112627131  ZNF354A; zinc finger protein 354A isoform X1 [KO:K09228]
112634293  RBAK; RB-associated KRAB zinc finger protein isoform X1 [KO:K09228]
112634329  zinc finger protein 268 isoform X1 [KO:K09228]
112634330  ZNF891; zinc finger protein 891 [KO:K09228]
112634331  ZNF140; zinc finger protein 140 isoform X1 [KO:K09228]
112605314  ZFP69B; zinc finger protein ZFP69B isoform X1 [KO:K09228]
112605349  zinc finger protein 682-like isoform X1 [KO:K09228]
112605362  ZNF670; zinc finger protein 670 isoform X1 [KO:K09228]
112605375  ZNF669; zinc finger protein 669 [KO:K09228]
112605383  ZNF124; zinc finger protein 124 isoform X1 [KO:K09228]
112612395  LOW QUALITY PROTEIN: zinc finger protein 813-like [KO:K09228]
112612396  zinc finger protein 845-like isoform X1 [KO:K09228]
112612436  ZNF160; zinc finger protein 160 isoform X1 [KO:K09228]
112612437  ZNF347; zinc finger protein 347 isoform X1 [KO:K09228]
112612439  zinc finger protein 600 isoform X1 [KO:K09228]
112612440  zinc finger protein 888 isoform X1 [KO:K09228]
112612441  ZNF665; zinc finger protein 665 isoform X1 [KO:K09228]
112612442  zinc finger protein 888-like isoform X1 [KO:K09228]
112612443  zinc finger protein 611 isoform X1 [KO:K09228]
112612444  zinc finger protein 816-like [KO:K09228]
112612447  ZNF415; zinc finger protein 415 isoform X1 [KO:K09228]
112612448  zinc finger protein 320-like [KO:K09228]
112612449  zinc finger protein 468 isoform X1 [KO:K09228]
112612450  ZNF677; zinc finger protein 677 [KO:K09228]
112612454  ZNF320; zinc finger protein 320 [KO:K09228]
112612455  zinc finger protein 813-like [KO:K09228]
112612470  zinc finger protein 480-like [KO:K09228]
112612472  zinc finger protein 610 isoform X1 [KO:K09228]
112612501  ZNF551; zinc finger protein 551 isoform X1 [KO:K09228]
112612502  ZNF671; zinc finger protein 671 [KO:K09228]
112612504  ZNF154; zinc finger protein 154 [KO:K09228]
112612528  ZNF333; zinc finger protein 333 isoform X1 [KO:K09228]
112612559  ZNF473; zinc finger protein 473 isoform X1 [KO:K09228]
112612569  ZNF180; zinc finger protein 180 isoform X1 [KO:K09228]
112612570  ZNF350; zinc finger protein 350 isoform X1 [KO:K09228]
112612602  ZNF584; zinc finger protein 584 isoform X1 [KO:K09228]
112612608  ZNF599; zinc finger protein 599 [KO:K09228]
112619776  ZNF621; zinc finger protein 621 isoform X1 [KO:K09228]
112619777  ZNF620; zinc finger protein 620 isoform X1 [KO:K09228]
112620099  ZNF3; zinc finger protein 3 isoform X1 [KO:K09228]
112620148  ZNF713; zinc finger protein 713 [KO:K09228]
112620178  LOW QUALITY PROTEIN: zinc finger protein 91-like [KO:K09228]
112620181  zinc finger protein 273 [KO:K09228]
112634616  ZNF26; zinc finger protein 26 isoform X1 [KO:K09228]
112634722  ZNF684; zinc finger protein 684 isoform X1 [KO:K09228]
112634821  ZNF641; zinc finger protein 641 isoform X1 [KO:K09228]
112611854  ZNF625; zinc finger protein 625 isoform X1 [KO:K09228]
112612058  zinc finger protein 724-like isoform X1 [KO:K09228]
112612397  zinc finger protein 761 [KO:K09228]
112612471  zinc finger protein 880-like [KO:K09228]
112612503  ZNF776; zinc finger protein 776 isoform X1 [KO:K09228]
112613176  zinc finger protein 266 isoform X1 [KO:K09228]
112613409  ZNF497; zinc finger protein 497 [KO:K09228]
112613615  zinc finger protein 28-like isoform X1 [KO:K09228]
112613817  zinc finger protein 764-like isoform X1 [KO:K09228]
112614683  ZNF720; putative protein ZNF720 isoform X1 [KO:K09228]
112620179  ZNF92; zinc finger protein 92 isoform X1 [KO:K09228]
112631673  ZNF485; zinc finger protein 485 isoform X1 [KO:K09228]
112632603  ZNF678; LOW QUALITY PROTEIN: zinc finger protein 678 [KO:K09228]
112613383  ZNF264; zinc finger protein 264 [KO:K09228]
112612060  zinc finger protein 681 [KO:K09228]
112612445  zinc finger protein 813-like isoform X1 [KO:K09228]
112612250  ZNF586; zinc finger protein 586 [KO:K09228]
112613254  BST2; bone marrow stromal antigen 2 [KO:K06731]
112634767  IFNG; interferon gamma [KO:K04687]
112622388  IFNGR1; interferon gamma receptor 1 isoform X1 [KO:K05132]
112620311  IFNGR2; interferon gamma receptor 2 [KO:K05133]
112608270  JAK2; tyrosine-protein kinase JAK2 isoform X1 [KO:K04447] [EC:2.7.10.2]
112623229  DAXX; death domain-associated protein 6 isoform X1 [KO:K02308]
112635928  SP100; nuclear autoantigen Sp-100 [KO:K15413]
112627469  PML; protein PML isoform X1 [KO:K10054] [EC:2.3.2.-]
112623507  TAP1; antigen peptide transporter 1 isoform X1 [KO:K05653] [EC:7.4.2.14]
112623508  TAP2; antigen peptide transporter 2 isoform X1 [KO:K05654] [EC:7.4.2.14]
112623232  TAPBP; tapasin isoform X1 [KO:K08058]
112627423  PDIA3; protein disulfide-isomerase A3 [KO:K08056] [EC:5.3.4.1]
112629733  calreticulin isoform X1 [KO:K08057]
112612583  CALR; LOW QUALITY PROTEIN: calreticulin [KO:K08057]
112622167  LOW QUALITY PROTEIN: patr class I histocompatibility antigen, A-108 alpha chain-like [KO:K06751]
112622184  popy class I histocompatibility antigen, alpha chain E-like isoform X1 [KO:K06751]
112622185  popy class I histocompatibility antigen, alpha chain E-like isoform X1 [KO:K06751]
112622400  HLA class I histocompatibility antigen, A-3 alpha chain isoform X1 [KO:K06751]
112622401  class I histocompatibility antigen, Gogo-B*0101 alpha chain isoform X1 [KO:K06751]
112622403  HLA class I histocompatibility antigen, B-14 alpha chain isoform X1 [KO:K06751]
112622405  HLA class I histocompatibility antigen, A-11 alpha chain-like isoform X1 [KO:K06751]
112622406  class I histocompatibility antigen, Gogo-B*0102 alpha chain-like isoform X1 [KO:K06751]
112622407  class I histocompatibility antigen, Gogo-B*0101 alpha chain-like isoform X1 [KO:K06751]
112622412  HLA class I histocompatibility antigen, B-14 alpha chain-like isoform X1 [KO:K06751]
112622432  LOW QUALITY PROTEIN: class I histocompatibility antigen, Gogo-B*0103 alpha chain-like [KO:K06751]
112616913  class I histocompatibility antigen, Gogo-B*0103 alpha chain-like isoform X1 [KO:K06751]
112616914  HLA class I histocompatibility antigen, Cw-12 alpha chain-like [KO:K06751]
112617631  HLA class I histocompatibility antigen, A-74 alpha chain-like [KO:K06751]
112617695  HLA class I histocompatibility antigen, B-14 alpha chain-like [KO:K06751]
112617731  HLA class I histocompatibility antigen, A-11 alpha chain-like isoform X1 [KO:K06751]
112617747  class I histocompatibility antigen, Gogo-B*0101 alpha chain-like isoform X1 [KO:K06751]
112617766  HLA class I histocompatibility antigen, B-40 alpha chain-like [KO:K06751]
112617801  HLA class I histocompatibility antigen, B-14 alpha chain-like isoform X1 [KO:K06751]
112617929  class I histocompatibility antigen, Gogo-B*0103 alpha chain-like [KO:K06751]
112617939  mamu class I histocompatibility antigen, alpha chain F isoform X1 [KO:K06751]
112627727  B2M; beta-2-microglobulin isoform X1 [KO:K08055]
112622042  HLA class II histocompatibility antigen, DP beta 1 chain isoform X1 [KO:K06752]
112622043  LOW QUALITY PROTEIN: HLA class II histocompatibility antigen, DP beta 1 chain-like [KO:K06752]
112622088  HLA class II histocompatibility antigen, DRB1-9 beta chain isoform X1 [KO:K06752]
112622413  HLA class II histocompatibility antigen, DRB1-1 beta chain-like isoform X1 [KO:K06752]
112622414  HLA class II histocompatibility antigen, DRB1-10 beta chain-like isoform X1 [KO:K06752]
112622415  HLA class II histocompatibility antigen, DR beta 5 chain isoform X1 [KO:K06752]
112622416  HLA class II histocompatibility antigen, DP alpha 1 chain [KO:K06752]
112622558  HLA class II histocompatibility antigen, DP alpha 1 chain-like [KO:K06752]
112622838  HLA class II histocompatibility antigen, DO alpha chain isoform X1 [KO:K06752]
112622959  mamu class II histocompatibility antigen, DR alpha chain isoform X1 [KO:K06752]
112623006  HLA class II histocompatibility antigen, DM beta chain isoform X1 [KO:K06752]
112623007  HLA class II histocompatibility antigen, DM alpha chain isoform X1 [KO:K06752]
112623510  HLA class II histocompatibility antigen, DO beta chain [KO:K06752]
112623518  HLA class II histocompatibility antigen, DQ beta 1 chain isoform X1 [KO:K06752]
112623519  HLA class II histocompatibility antigen, DQ alpha 2 chain [KO:K06752]
112626003  CD74; HLA class II histocompatibility antigen gamma chain isoform X1 [KO:K06505]
112618874  PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
112634042  PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform [KO:K00922] [EC:2.7.1.153]
112619294  PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
112614522  PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1 [KO:K02649]
112625914  PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
112612001  PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta isoform X1 [KO:K02649]
112629473  AKT1; RAC-alpha serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
112609286  AKT3; RAC-gamma serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
112612288  AKT2; RAC-beta serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
112607854  TSC1; hamartin isoform X1 [KO:K07206]
112614277  TSC2; tuberin isoform X1 [KO:K07207]
112620291  RHEB; GTP-binding protein Rheb [KO:K07208]
112623568  MTOR; serine/threonine-protein kinase mTOR [KO:K07203] [EC:2.7.11.1]
112630672  EIF4EBP1; eukaryotic translation initiation factor 4E-binding protein 1 [KO:K07205]
112622982  SRPK1; SRSF protein kinase 1 isoform X1 [KO:K15409] [EC:2.7.11.1]
112608943  SRSF1; serine/arginine-rich splicing factor 1 [KO:K12890]
112606576  serine/arginine-rich splicing factor 8-like isoform X1 [KO:K12891]
112606748  SRSF8; serine/arginine-rich splicing factor 8 isoform X1 [KO:K12891]
112610349  SRSF2; serine/arginine-rich splicing factor 2 isoform X1 [KO:K12891]
112623310  SRSF3; serine/arginine-rich splicing factor 3 [KO:K12892]
112629273  SRSF5; serine/arginine-rich splicing factor 5 isoform X1 [KO:K12893]
112617438  serine/arginine-rich splicing factor 4 [KO:K12893]
112632811  SRSF6; serine/arginine-rich splicing factor 6 isoform X1 [KO:K12893]
112610706  serine/arginine-rich splicing factor 4-like [KO:K12893]
112636915  SRSF7; serine/arginine-rich splicing factor 7 isoform X1 [KO:K12896]
112635523  SRSF9; serine/arginine-rich splicing factor 9 isoform X1 [KO:K21123]
112615458  nuclear RNA export factor 2 [KO:K14284]
112615530  NXF3; nuclear RNA export factor 3 isoform X1 [KO:K14284]
112616002  nuclear RNA export factor 2-like [KO:K14284]
112606081  NXF1; nuclear RNA export factor 1 [KO:K14284]
112609424  ALYREF; THO complex subunit 4 [KO:K12881]
112636918  FASLG; tumor necrosis factor ligand superfamily member 6 isoform X1 [KO:K04389]
112631569  FAS; tumor necrosis factor receptor superfamily member 6 isoform X1 [KO:K04390]
112635096  TNFRSF1A; tumor necrosis factor receptor superfamily member 1A isoform X1 [KO:K03158]
112614422  TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein isoform X1 [KO:K03171]
112606728  FADD; FAS-associated death domain protein [KO:K02373]
112636264  CASP8; caspase-8 isoform X1 [KO:K04398] [EC:3.4.22.61]
112632621  BID; BH3-interacting domain death agonist isoform X1 [KO:K04726]
112613606  BAX; apoptosis regulator BAX isoform X1 [KO:K02159]
112622824  BAK1; bcl-2 homologous antagonist/killer isoform X1 [KO:K14021]
112606473  BAD; bcl2-associated agonist of cell death isoform X1 [KO:K02158]
112611529  BCL2; apoptosis regulator Bcl-2 isoform X1 [KO:K02161]
112632856  BCL2L1; bcl-2-like protein 1 isoform X1 [KO:K04570]
112620387  cytochrome c, somatic [KO:K08738]
112621297  cytochrome c [KO:K08738]
112622774  cytochrome c-like [KO:K08738]
112623008  cytochrome c-like [KO:K08738]
112608628  cytochrome c-like [KO:K08738]
112614550  cytochrome c-like [KO:K08738]
112625466  cytochrome c [KO:K08738]
112611588  cytochrome c-like [KO:K08738]
112626808  cytochrome c-like [KO:K08738]
112634215  cytochrome c-like [KO:K08738]
112605628  cytochrome c-like [KO:K08738]
112618713  cytochrome c-like [KO:K08738]
112634060  APAF1; apoptotic protease-activating factor 1 isoform X1 [KO:K02084]
112628633  CASP9; caspase-9 isoform X1 [KO:K04399] [EC:3.4.22.62]
112622580  LOW QUALITY PROTEIN: caspase-3-like [KO:K02187] [EC:3.4.22.56]
112625066  CASP3; caspase-3 isoform X1 [KO:K02187] [EC:3.4.22.56]
Compound
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C20640  Cyclic GMP-AMP
C20935  2-5A
Reference
  Authors
Granger SW, Rickert S
  Title
LIGHT-HVEM signaling and the regulation of T cell-mediated immunity.
  Journal
Cytokine Growth Factor Rev 14:289-96 (2003)
DOI:10.1016/S1359-6101(03)00031-5
Reference
  Authors
Steinberg MW, Shui JW, Ware CF, Kronenberg M
  Title
Regulating the mucosal immune system: the contrasting roles of LIGHT, HVEM, and their various partners.
  Journal
Semin Immunopathol 31:207-21 (2009)
DOI:10.1007/s00281-009-0157-4
Reference
  Authors
MacLeod IJ, Minson T
  Title
Binding of herpes simplex virus type-1 virions leads to the induction of intracellular signalling in the absence of virus entry.
  Journal
PLoS One 5:e9560 (2010)
DOI:10.1371/journal.pone.0009560
Reference
  Authors
Gianni T, Leoni V, Chesnokova LS, Hutt-Fletcher LM, Campadelli-Fiume G
  Title
alphavbeta3-integrin is a major sensor and activator of innate immunity to herpes simplex virus-1.
  Journal
Proc Natl Acad Sci U S A 109:19792-7 (2012)
DOI:10.1073/pnas.1212597109
Reference
  Authors
Gianni T, Campadelli-Fiume G
  Title
The epithelial alphavbeta3-integrin boosts the MYD88-dependent TLR2 signaling in response to viral and bacterial components.
  Journal
PLoS Pathog 10:e1004477 (2014)
DOI:10.1371/journal.ppat.1004477
Reference
  Authors
Spear PG
  Title
Herpes simplex virus: receptors and ligands for cell entry.
  Journal
Cell Microbiol 6:401-10 (2004)
DOI:10.1111/j.1462-5822.2004.00389.x
Reference
  Authors
Boutell C, Everett RD
  Title
The herpes simplex virus type 1 (HSV-1) regulatory protein ICP0 interacts with and Ubiquitinates p53.
  Journal
J Biol Chem 278:36596-602 (2003)
DOI:10.1074/jbc.M300776200
Reference
  Authors
Ma Y, He B
  Title
Recognition of herpes simplex viruses: toll-like receptors and beyond.
  Journal
J Mol Biol 426:1133-47 (2014)
DOI:10.1016/j.jmb.2013.11.012
Reference
  Authors
Su C, Zhan G, Zheng C
  Title
Evasion of host antiviral innate immunity by HSV-1, an update.
  Journal
Virol J 13:38 (2016)
DOI:10.1186/s12985-016-0495-5
Reference
  Authors
Melchjorsen J, Matikainen S, Paludan SR
  Title
Activation and evasion of innate antiviral immunity by herpes simplex virus.
  Journal
Viruses 1:737-59 (2009)
DOI:10.3390/v1030737
Reference
  Authors
Morrison LA
  Title
The Toll of herpes simplex virus infection.
  Journal
Trends Microbiol 12:353-6 (2004)
DOI:10.1016/j.tim.2004.06.001
Reference
  Authors
Zheng C
  Title
Evasion of Cytosolic DNA-Stimulated Innate Immune Responses by Herpes Simplex Virus 1.
  Journal
J Virol 92:e00099-17 (2018)
DOI:10.1128/JVI.00099-17
Reference
  Authors
Grandi P, Peruzzi P, Reinhart B, Cohen JB, Chiocca EA, Glorioso JC
  Title
Design and application of oncolytic HSV vectors for glioblastoma therapy.
  Journal
Expert Rev Neurother 9:505-17 (2009)
DOI:10.1586/ern.09.9
Reference
  Authors
Lussignol M, Queval C, Bernet-Camard MF, Cotte-Laffitte J, Beau I, Codogno P, Esclatine A
  Title
The herpes simplex virus 1 Us11 protein inhibits autophagy through its interaction with the protein kinase PKR.
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J Virol 87:859-71 (2013)
DOI:10.1128/JVI.01158-12
Reference
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Sanchez R, Mohr I
  Title
Inhibition of cellular 2'-5' oligoadenylate synthetase by the herpes simplex virus type 1 Us11 protein.
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J Virol 81:3455-64 (2007)
DOI:10.1128/JVI.02520-06
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Wysocka J, Herr W
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The herpes simplex virus VP16-induced complex: the makings of a regulatory switch.
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Trends Biochem Sci 28:294-304 (2003)
DOI:10.1016/S0968-0004(03)00088-4
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Fleming SB
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Viral Inhibition of the IFN-Induced JAK/STAT Signalling Pathway: Development of Live Attenuated Vaccines by Mutation of Viral-Encoded IFN-Antagonists.
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Vaccines (Basel) 4:E23 (2016)
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Yokota S, Yokosawa N, Okabayashi T, Suzutani T, Miura S, Jimbow K, Fujii N
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Induction of suppressor of cytokine signaling-3 by herpes simplex virus type 1 contributes to inhibition of the interferon signaling pathway.
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J Virol 78:6282-6 (2004)
DOI:10.1128/JVI.78.12.6282-6286.2004
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Gu H, Zheng Y, Roizman B
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Interaction of herpes simplex virus ICP0 with ND10 bodies: a sequential process of adhesion, fusion, and retention.
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J Virol 87:10244-54 (2013)
DOI:10.1128/JVI.01487-13
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Tavalai N, Stamminger T
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Interplay between Herpesvirus Infection and Host Defense by PML Nuclear Bodies.
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Viruses 1:1240-64 (2009)
DOI:10.3390/v1031240
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Horst D, Verweij MC, Davison AJ, Ressing ME, Wiertz EJ
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Viral evasion of T cell immunity: ancient mechanisms offering new applications.
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Curr Opin Immunol 23:96-103 (2011)
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Neumann J, Eis-Hubinger AM, Koch N
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Herpes simplex virus type 1 targets the MHC class II processing pathway for immune evasion.
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J Immunol 171:3075-83 (2003)
DOI:10.4049/jimmunol.171.6.3075
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Liu X, Cohen JI
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The role of PI3K/Akt in human herpesvirus infection: From the bench to the bedside.
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Virology 479-480:568-77 (2015)
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Vink EI, Smiley JR, Mohr I
  Title
Subversion of Host Responses to Energy Insufficiency by Us3 Supports Herpes Simplex Virus 1 Replication during Stress.
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J Virol 91:e00295-17 (2017)
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Sandri-Goldin RM
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The many roles of the regulatory protein ICP27 during herpes simplex virus infection.
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Front Biosci 13:5241-56 (2008)
DOI:10.2741/3078
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Sandri-Goldin RM
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Viral regulation of mRNA export.
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J Virol 78:4389-96 (2004)
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Yu X, He S
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The interplay between human herpes simplex virus infection and the apoptosis and necroptosis cell death pathways.
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Virol J 13:77 (2016)
DOI:10.1186/s12985-016-0528-0
Related
pathway
tge03040  Spliceosome
tge03050  Proteasome
tge04115  p53 signaling pathway
tge04151  PI3K-Akt signaling pathway
tge04210  Apoptosis
tge04610  Complement and coagulation cascades
tge04612  Antigen processing and presentation
tge04620  Toll-like receptor signaling pathway
tge04622  RIG-I-like receptor signaling pathway
tge04630  JAK-STAT signaling pathway
KO pathway
ko05168   
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