KEGG   PATHWAY: epz05132
Entry
epz05132                    Pathway                                
Name
Salmonella infection - Equus przewalskii (Przewalski's horse)
Description
Salmonella infection usually presents as a self-limiting gastroenteritis or the more severe typhoid fever and bacteremia. The common disease-causing Salmonella species in human is a single species, Salmonella enterica, which has numerous serovars.
Following intestinal colonization Salmonella inject effector proteins into the host cells using a type III secretion system (T3SS), T3SS1. Then a small group of effector proteins induce rearrangement of the actin cytoskeleton resulting in membrane ruffles and rapid internalization of the bacteria.The T3SS2 is responsible for translocating effector proteins that direct Salmonella-containing vacuole (SCV) maturation. The majority of the bacteria are known to survive and replicate in SCV.
Class
Human Diseases; Infectious disease: bacterial
Pathway map
epz05132  Salmonella infection
epz05132

Organism
Equus przewalskii (Przewalski's horse) [GN:epz]
Gene
103553382  PODXL; podocalyxin like [KO:K06817]
103567341  PTPRC; protein tyrosine phosphatase, receptor type C [KO:K06478] [EC:3.1.3.48]
103559349  RAB5A; RAB5A, member RAS oncogene family [KO:K07887]
103560194  RAB5B; RAB5B, member RAS oncogene family [KO:K07888]
103550370  RAB5C; RAB5C, member RAS oncogene family [KO:K07889]
103543294  phosphatidylinositol 3-kinase catalytic subunit type 3-like [KO:K00914] [EC:2.7.1.137]
103540291  RAB7A; RAB7A, member RAS oncogene family [KO:K07897]
103553830  RAB7B; RAB7B, member RAS oncogene family [KO:K07898]
103554687  PLEKHM1; pleckstrin homology and RUN domain containing M1 [KO:K23282]
103546652  VPS11; VPS11, CORVET/HOPS core subunit [KO:K20179]
103555820  VPS16; VPS16, CORVET/HOPS core subunit [KO:K20180]
103564730  VPS18; VPS18, CORVET/HOPS core subunit [KO:K20181]
103541188  VPS33A; VPS33A, CORVET/HOPS core subunit [KO:K20182]
103549944  VPS39; VPS39, HOPS complex subunit [KO:K20183]
103563898  VPS41; VPS41, HOPS complex subunit [KO:K20184]
103562601  RILP; Rab interacting lysosomal protein [KO:K13883]
103556450  DYNC1H1; dynein cytoplasmic 1 heavy chain 1 [KO:K10413]
103555009  DYNC1I1; dynein cytoplasmic 1 intermediate chain 1 [KO:K10415]
103555657  DYNC1I2; dynein cytoplasmic 1 intermediate chain 2 [KO:K10415]
103542646  DYNC1LI2; dynein cytoplasmic 1 light intermediate chain 2 [KO:K10416]
103564814  DYNC1LI1; dynein cytoplasmic 1 light intermediate chain 1 [KO:K10416]
103547789  DYNC2LI1; dynein cytoplasmic 2 light intermediate chain 1 [KO:K10417]
103540545  DYNLL1; dynein light chain LC8-type 1 [KO:K10418]
103546334  DYNLL2; dynein light chain LC8-type 2 [KO:K10418]
103553778  DYNLRB1; dynein light chain roadblock-type 1 [KO:K10419]
103541814  DYNLRB2; dynein light chain roadblock-type 2 [KO:K10419]
103554095  DYNLT1; dynein light chain Tctex-type 1 [KO:K10420]
103540977  DYNLT3; dynein light chain Tctex-type 3 [KO:K10420]
103564989  DCTN1; dynactin subunit 1 [KO:K04648]
103559781  DCTN2; dynactin subunit 2 [KO:K10424]
103542633  DCTN3; dynactin subunit 3 [KO:K10425]
103549108  DCTN4; dynactin subunit 4 [KO:K10426]
103562659  DCTN5; dynactin subunit 5 [KO:K10427]
103543569  DCTN6; dynactin subunit 6 [KO:K10428]
103558144  ACTR1A; ARP1 actin-related protein 1 homolog A, centractin alpha [KO:K16575]
103561438  ACTR1B; ARP1 actin-related protein 1 homolog B, centractin beta [KO:K16575]
103564367  ACTR10; actin-related protein 10 homolog [KO:K16576]
103548881  TUBAL3; tubulin alpha like 3 [KO:K07374]
103549035  tubulin alpha-3 chain [KO:K07374]
103552206  tubulin alpha-1C chain [KO:K07374]
103552226  tubulin alpha-1C chain-like [KO:K07374]
103557442  TUBA4A; tubulin alpha 4a [KO:K07374]
103541363  TUBA8; tubulin alpha 8 [KO:K07374]
103567863  tubulin alpha-3 chain-like [KO:K07374]
103557184  TUBB6; tubulin beta 6 class V [KO:K07375]
103541425  tubulin beta-3 chain-like [KO:K07375]
103556319  tubulin beta-2B chain [KO:K07375]
103563572  tubulin beta chain [KO:K07375]
103567168  TUBB; tubulin beta class I [KO:K07375]
103565407  TUBB1; tubulin beta 1 class VI [KO:K07375]
103542209  tubulin beta chain-like [KO:K07375]
103555070  FYCO1; FYVE and coiled-coil domain containing 1 [KO:K21954]
103560595  ARL8B; ADP ribosylation factor like GTPase 8B [KO:K07955]
103567459  ARL8A; ADP ribosylation factor like GTPase 8A [KO:K07955]
103552941  PLEKHM2; pleckstrin homology and RUN domain containing M2 [KO:K15348]
103558759  KIF5C; kinesin family member 5C [KO:K10396]
103560162  KIF5B; kinesin family member 5B [KO:K10396]
103559780  KIF5A; kinesin family member 5A [KO:K10396]
103548162  KLC4; kinesin light chain 4 [KO:K10407]
103559532  KLC2; kinesin light chain 2 [KO:K10407]
103567005  KLC3; kinesin light chain 3 [KO:K10407]
103563409  KLC1; kinesin light chain 1 [KO:K10407]
103568022  ACBD3; acyl-CoA binding domain containing 3 [KO:K23935]
103553409  RHOA; ras homolog family member A [KO:K04513]
103542483  M6PR; mannose-6-phosphate receptor, cation dependent [KO:K10089]
103543558  RAB9A; RAB9A, member RAS oncogene family [KO:K07899]
103543114  RAB9B; RAB9B, member RAS oncogene family [KO:K07900]
103566356  GCC2; GRIP and coiled-coil domain containing 2 [KO:K20282]
103567237  STX10; syntaxin 10 [KO:K23937]
103547830  PFN4; profilin family member 4 [KO:K05759]
103539970  PFN3; profilin 3 [KO:K05759]
103543790  profilin-1-like [KO:K05759]
103560657  PFN1; profilin 1 [KO:K05759]
103563312  PFN2; profilin 2 [KO:K05759]
103544977  filamin-A-like [KO:K04437]
103566054  EXOC7; exocyst complex component 7 [KO:K07195]
103558592  EXOC5; exocyst complex component 5 [KO:K19984]
103565564  exocyst complex component 4-like [KO:K06111]
103542063  exocyst complex component 2-like [KO:K17637]
103563476  RALA; RAS like proto-oncogene A [KO:K07834]
103551082  ACTG1; actin gamma 1 [KO:K05692]
103547895  ACTB; actin beta [KO:K05692]
103547920  S100A10; S100 calcium binding protein A10 [KO:K17274]
103546756  ANXA2; annexin A2 [KO:K17092]
103541061  protein AHNAK2-like [KO:K23934]
103558928  AHNAK; AHNAK nucleoprotein [KO:K23934]
103540565  protein AHNAK2-like [KO:K23934]
103552435  RHOJ; ras homolog family member J [KO:K07864]
103555967  rho guanine nucleotide exchange factor 26-like [KO:K13744]
103544431  rho-related GTP-binding protein RhoG-like [KO:K07863]
103558524  RHOG; ras homolog family member G [KO:K07863]
103561467  ELMO1; engulfment and cell motility 1 [KO:K12366]
103551915  ELMO2; engulfment and cell motility 2 [KO:K18985]
103557393  ROCK2; Rho associated coiled-coil containing protein kinase 2 [KO:K17388] [EC:2.7.11.1]
103544050  myosin regulatory light chain 2, ventricular/cardiac muscle isoform-like [KO:K10351]
103566770  myosin light chain 5-like [KO:K12753]
103554942  MYL7; myosin light chain 7 [KO:K12754]
103557622  MYL9; myosin light chain 9 [KO:K12755]
103551717  MYL10; myosin light chain 10 [KO:K12756]
103559953  myosin regulatory light chain 12B [KO:K12757]
103559954  myosin regulatory light polypeptide 9 [KO:K12757]
103547213  MYLPF; myosin light chain, phosphorylatable, fast skeletal muscle [KO:K12758]
103542336  FHOD1; formin homology 2 domain containing 1 [KO:K23938]
103558482  CDC42; cell division cycle 42 [KO:K04393]
103552260  ras-related C3 botulinum toxin substrate 1-like [KO:K04392]
103553219  NCKAP1; NCK associated protein 1 [KO:K05750]
103563244  NCKAP1L; NCK associated protein 1 like [KO:K05750]
103547651  CYFIP2; cytoplasmic FMR1 interacting protein 2 [KO:K05749]
103560861  ABI1; abl interactor 1 [KO:K23649]
103561460  BRK1; BRICK1, SCAR/WAVE actin nucleating complex subunit [KO:K05752]
103561699  WASF3; WAS protein family member 3 [KO:K06083]
103560803  ACTR2; ARP2 actin related protein 2 homolog [KO:K17260]
103561014  ACTR3; ARP3 actin related protein 3 homolog [KO:K18584]
103541825  ACTR3B; ARP3 actin related protein 3 homolog B [KO:K18584]
103548324  ARPC1A; actin related protein 2/3 complex subunit 1A [KO:K05757]
103548326  ARPC1B; actin related protein 2/3 complex subunit 1B [KO:K05757]
103564147  ARPC2; actin related protein 2/3 complex subunit 2 [KO:K05758]
103541523  ARPC3; actin related protein 2/3 complex subunit 3 [KO:K05756]
103566630  ARPC4; actin related protein 2/3 complex subunit 4 [KO:K05755]
103552052  ARPC5; actin related protein 2/3 complex subunit 5 [KO:K05754]
103556334  ARPC5L; actin related protein 2/3 complex subunit 5 like [KO:K05754]
103553799  PAK1; p21 (RAC1) activated kinase 1 [KO:K04409] [EC:2.7.11.1]
103566208  PAK3; p21 (RAC1) activated kinase 3 [KO:K05733] [EC:2.7.11.1]
103563647  MYO6; myosin VI [KO:K10358]
103549076  PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta [KO:K00922] [EC:2.7.1.153]
103554655  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform-like [KO:K00922] [EC:2.7.1.153]
103552150  PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha [KO:K00922] [EC:2.7.1.153]
103557800  PIK3CG; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma [KO:K21289] [EC:2.7.1.153]
103565099  phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma-like [KO:K00923] [EC:2.7.1.154]
103557140  PIK3C2A; phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha [KO:K00923] [EC:2.7.1.154]
103567844  phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta-like [KO:K00923] [EC:2.7.1.154]
103551448  CYTH1; cytohesin 1 [KO:K18441]
103555775  CYTH3; cytohesin 3 [KO:K18441]
103541382  CYTH2; cytohesin 2 [KO:K18441]
103564459  CYTH4; cytohesin 4 [KO:K18441]
103556125  ARF6; ADP ribosylation factor 6 [KO:K07941]
103565871  ARF1; ADP ribosylation factor 1 [KO:K07937]
103552911  ADP-ribosylation factor 2 [KO:K07937]
103552337  SNX33; sorting nexin 33 [KO:K17923]
103558182  SNX18; sorting nexin 18 [KO:K17923]
103559642  SNX9; sorting nexin 9 [KO:K17923]
103560646  WASL; Wiskott-Aldrich syndrome like [KO:K23612]
103562422  DNM2; dynamin 2 [KO:K23484] [EC:3.6.5.5]
103551263  TLR6; toll like receptor 6 [KO:K10169]
103553736  TLR2; toll like receptor 2 [KO:K10159]
103549023  TIRAP; TIR domain containing adaptor protein [KO:K05403]
103557961  MYD88; myeloid differentiation primary response 88 [KO:K04729]
103548018  CD14; CD14 molecule [KO:K04391]
103562040  TLR4; toll like receptor 4 [KO:K10160]
103565249  LY96; lymphocyte antigen 96 [KO:K05400]
103559682  TLR5; toll like receptor 5 [KO:K10168]
103546489  TLR9; toll like receptor 9 [KO:K10161]
103545279  IRAK1; interleukin 1 receptor associated kinase 1 [KO:K04730] [EC:2.7.11.1]
103547487  IRAK4; interleukin 1 receptor associated kinase 4 [KO:K04733] [EC:2.7.11.1]
103560236  TRAF6; TNF receptor associated factor 6 [KO:K03175] [EC:2.3.2.27]
103548805  MAP3K7; mitogen-activated protein kinase kinase kinase 7 [KO:K04427] [EC:2.7.11.25]
103542619  TAB1; TGF-beta activated kinase 1 (MAP3K7) binding protein 1 [KO:K04403]
103548723  TAB2; TGF-beta activated kinase 1/MAP3K7 binding protein 2 [KO:K04404]
103565693  TAB3; TGF-beta activated kinase 1/MAP3K7 binding protein 3 [KO:K12793]
103543979  NF-kappa-B essential modulator-like [KO:K07210]
103567228  CHUK; conserved helix-loop-helix ubiquitous kinase [KO:K04467] [EC:2.7.11.10]
103562903  IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta [KO:K07209] [EC:2.7.11.10]
103546400  NFKBIA; NFKB inhibitor alpha [KO:K04734]
103556719  NFKB1; nuclear factor kappa B subunit 1 [KO:K02580]
103543692  RELA; RELA proto-oncogene, NF-kB subunit [KO:K04735]
103552757  NOD1; nucleotide binding oligomerization domain containing 1 [KO:K08727]
103564893  HSP90AB1; heat shock protein 90 alpha family class B member 1 [KO:K04079]
103556444  HSP90AA1; heat shock protein 90 alpha family class A member 1 [KO:K04079]
103562002  HSP90B1; heat shock protein 90 beta family member 1 [KO:K09487]
103564122  RIPK2; receptor interacting serine/threonine kinase 2 [KO:K08846] [EC:2.7.11.1]
103565846  exportin-2 [KO:K18423]
103564606  CSE1L; chromosome segregation 1 like [KO:K18423]
103548430  KPNA1; karyopherin subunit alpha 1 [KO:K23940]
103563285  KPNA3; karyopherin subunit alpha 3 [KO:K23583]
103563327  KPNA4; karyopherin subunit alpha 4 [KO:K23583]
103542686  40S ribosomal protein S3 [KO:K02985]
103542338  RPS3; ribosomal protein S3 [KO:K02985]
103567332  HRAS; HRas proto-oncogene, GTPase [KO:K02833]
103554541  RAF1; Raf-1 proto-oncogene, serine/threonine kinase [KO:K04366] [EC:2.7.11.1]
103549630  MAP2K1; mitogen-activated protein kinase kinase 1 [KO:K04368] [EC:2.7.12.2]
103543290  dual specificity mitogen-activated protein kinase kinase 2-like [KO:K04369] [EC:2.7.12.2]
103547261  MAPK3; mitogen-activated protein kinase 3 [KO:K04371] [EC:2.7.11.24]
103562408  MAPK1; mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
103563092  MAP2K3; mitogen-activated protein kinase kinase 3 [KO:K04432] [EC:2.7.12.2]
103564566  MAP2K6; mitogen-activated protein kinase kinase 6 [KO:K04433] [EC:2.7.12.2]
103565534  MAPK14; mitogen-activated protein kinase 14 [KO:K04441] [EC:2.7.11.24]
103563198  MAPK13; mitogen-activated protein kinase 13 [KO:K04441] [EC:2.7.11.24]
103559485  MAPK12; mitogen-activated protein kinase 12 [KO:K04441] [EC:2.7.11.24]
103559491  MAPK11; mitogen-activated protein kinase 11 [KO:K04441] [EC:2.7.11.24]
103567795  dual specificity mitogen-activated protein kinase kinase 4-like [KO:K04430] [EC:2.7.12.2]
103543808  MAP2K7; mitogen-activated protein kinase kinase 7 [KO:K04431] [EC:2.7.12.2]
103549414  MAPK8; mitogen-activated protein kinase 8 [KO:K04440] [EC:2.7.11.24]
103553980  MAPK10; mitogen-activated protein kinase 10 [KO:K04440] [EC:2.7.11.24]
103567629  MAPK9; mitogen-activated protein kinase 9 [KO:K04440] [EC:2.7.11.24]
103548618  FOS; Fos proto-oncogene, AP-1 transcription factor subunit [KO:K04379]
103562469  TNF; tumor necrosis factor [KO:K03156]
103544835  IL1B; interleukin 1 beta [KO:K04519]
103561141  IL6; interleukin 6 [KO:K05405]
103566768  CXCL8; C-X-C motif chemokine ligand 8 [KO:K10030]
103552888  CTNNB1; catenin beta 1 [KO:K02105]
103543120  TCF7; transcription factor 7 (T-cell specific, HMG-box) [KO:K02620]
103548276  TCF7L1; transcription factor 7 like 1 [KO:K04490]
103564289  TCF7L2; transcription factor 7 like 2 [KO:K04491]
103557035  LEF1; lymphoid enhancer binding factor 1 [KO:K04492]
103567860  MYC; v-myc avian myelocytomatosis viral oncogene homolog [KO:K04377]
103543541  PKN1; protein kinase N1 [KO:K06071] [EC:2.7.11.13]
103560061  FBXO22; F-box protein 22 [KO:K10302]
103543154  SKP1; S-phase kinase associated protein 1 [KO:K03094]
103546993  TNFRSF1A; TNF receptor superfamily member 1A [KO:K03158]
103567822  TRAF2; TNF receptor associated factor 2 [KO:K03173] [EC:2.3.2.27]
103542683  TRADD; TNFRSF1A associated via death domain [KO:K03171]
103552625  BIRC3; baculoviral IAP repeat containing 3 [KO:K16060]
103552627  BIRC2; baculoviral IAP repeat containing 2 [KO:K16060]
103556321  RIPK1; receptor interacting serine/threonine kinase 1 [KO:K02861] [EC:2.7.11.1]
103547001  GAPDH; glyceraldehyde-3-phosphate dehydrogenase [KO:K00134] [EC:1.2.1.12]
103546356  TNFSF10; tumor necrosis factor superfamily member 10 [KO:K04721]
103552761  TNFRSF10B; TNF receptor superfamily member 10b [KO:K04722]
103566999  FADD; Fas associated via death domain [KO:K02373]
103565685  CASP8; caspase 8 [KO:K04398] [EC:3.4.22.61]
103561048  RIPK3; receptor interacting serine/threonine kinase 3 [KO:K08847] [EC:2.7.11.1]
103553312  BAX; BCL2 associated X, apoptosis regulator [KO:K02159]
103544222  BAK1; BCL2 antagonist/killer 1 [KO:K14021]
103547975  cytochrome c, testis-specific [KO:K08738]
103561978  cytochrome c [KO:K08738]
103550767  BCL2; BCL2, apoptosis regulator [KO:K02161]
103549132  CASP3; caspase 3 [KO:K02187] [EC:3.4.22.56]
103540204  CASP7; caspase 7 [KO:K04397] [EC:3.4.22.60]
103562207  RHOB; ras homolog family member B [KO:K07856]
103553457  RHOH; ras homolog family member H [KO:K07873]
103560497  AKT2; AKT serine/threonine kinase 2 [KO:K04456] [EC:2.7.11.1]
103540249  AKT1; AKT serine/threonine kinase 1 [KO:K04456] [EC:2.7.11.1]
103555421  AKT3; AKT serine/threonine kinase 3 [KO:K04456] [EC:2.7.11.1]
103560158  MLKL; mixed lineage kinase domain like pseudokinase [KO:K08849] [EC:2.7.11.1]
103546784  TXN; thioredoxin [KO:K03671]
103541846  TXN2; thioredoxin 2 [KO:K03671]
103565123  NACHT, LRR and PYD domains-containing protein 3-like [KO:K12800]
103564225  NAIP; NLR family apoptosis inhibitory protein [KO:K12807]
103567720  NLRC4; NLR family CARD domain containing 4 [KO:K12805]
103547248  apoptosis-associated speck-like protein containing a CARD [KO:K12799]
103559838  CASP1; caspase 1 [KO:K01370] [EC:3.4.22.36]
103565880  IL18; interleukin 18 [KO:K05482]
103559837  caspase-13-like [KO:K04394] [EC:3.4.22.57 3.4.22.64]
103559840  caspase-13-like [KO:K04394] [EC:3.4.22.57 3.4.22.64]
103561591  GSDMD; gasdermin D [KO:K20917]
Compound
C00338  Lipopolysaccharide
C01194  1-Phosphatidyl-D-myo-inositol
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
Reference
PMID:28875943
  Authors
Bernal-Bayard J, Ramos-Morales F
  Title
Molecular Mechanisms Used by Salmonella to Evade the Immune System.
  Journal
Curr Issues Mol Biol 25:133-168 (2018)
DOI:10.21775/cimb.025.133
Reference
PMID:28848711
  Authors
Hume PJ, Singh V, Davidson AC, Koronakis V
  Title
Swiss Army Pathogen: The Salmonella Entry Toolkit.
  Journal
Front Cell Infect Microbiol 7:348 (2017)
DOI:10.3389/fcimb.2017.00348
Reference
PMID:31402916
  Authors
Wemyss MA, Pearson JS
  Title
Host Cell Death Responses to Non-typhoidal Salmonella Infection.
  Journal
Front Immunol 10:1758 (2019)
DOI:10.3389/fimmu.2019.01758
Reference
PMID:27974148
  Authors
Bierschenk D, Boucher D, Schroder K
  Title
Salmonella-induced inflammasome activation in humans.
  Journal
Mol Immunol 86:38-43 (2017)
DOI:10.1016/j.molimm.2016.11.009
Reference
PMID:29477730
  Authors
Pinaud L, Sansonetti PJ, Phalipon A
  Title
Host Cell Targeting by Enteropathogenic Bacteria T3SS Effectors.
  Journal
Trends Microbiol 26:266-283 (2018)
DOI:10.1016/j.tim.2018.01.010
Reference
PMID:25749450
  Authors
LaRock DL, Chaudhary A, Miller SI
  Title
Salmonellae interactions with host processes.
  Journal
Nat Rev Microbiol 13:191-205 (2015)
DOI:10.1038/nrmicro3420
Reference
PMID:17983751
  Authors
Ramsden AE, Holden DW, Mota LJ
  Title
Membrane dynamics and spatial distribution of Salmonella-containing vacuoles.
  Journal
Trends Microbiol 15:516-24 (2007)
DOI:10.1016/j.tim.2007.10.002
Reference
PMID:22702524
  Authors
van der Heijden J, Finlay BB
  Title
Type III effector-mediated processes in Salmonella infection.
  Journal
Future Microbiol 7:685-703 (2012)
DOI:10.2217/fmb.12.49
Reference
PMID:27222578
  Authors
Galan JE
  Title
Typhoid toxin provides a window into typhoid fever and the biology of Salmonella Typhi.
  Journal
Proc Natl Acad Sci U S A 113:6338-44 (2016)
DOI:10.1073/pnas.1606335113
Reference
PMID:19157959
  Authors
McGhie EJ, Brawn LC, Hume PJ, Humphreys D, Koronakis V
  Title
Salmonella takes control: effector-driven manipulation of the host.
  Journal
Curr Opin Microbiol 12:117-24 (2009)
DOI:10.1016/j.mib.2008.12.001
Reference
PMID:12675800
  Authors
Miao EA, Brittnacher M, Haraga A, Jeng RL, Welch MD, Miller SI
  Title
Salmonella effectors translocated across the vacuolar membrane interact with the actin cytoskeleton.
  Journal
Mol Microbiol 48:401-15 (2003)
DOI:10.1046/j.1365-2958.2003.t01-1-03456.x
Reference
PMID:17074883
  Authors
Patel JC, Galan JE
  Title
Differential activation and function of Rho GTPases during Salmonella-host cell interactions.
  Journal
J Cell Biol 175:453-63 (2006)
DOI:10.1083/jcb.200605144
Reference
PMID:18411289
  Authors
Wasylnka JA, Bakowski MA, Szeto J, Ohlson MB, Trimble WS, Miller SI, Brumell JH
  Title
Role for myosin II in regulating positioning of Salmonella-containing vacuoles and intracellular replication.
  Journal
Infect Immun 76:2722-35 (2008)
DOI:10.1128/IAI.00152-08
Reference
PMID:10499590
  Authors
Fu Y, Galan JE
  Title
A salmonella protein antagonizes Rac-1 and Cdc42 to mediate host-cell recovery after bacterial invasion.
  Journal
Nature 401:293-7 (1999)
DOI:10.1038/45829
Related
pathway
epz04010  MAPK signaling pathway
epz04064  NF-kappa B signaling pathway
epz04210  Apoptosis
epz04217  Necroptosis
epz04621  NOD-like receptor signaling pathway
KO pathway
ko05132   
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