ORTHOLOGY: K07994
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Entry
K07994 KO
Symbol
MMP13
Name
matrix metalloproteinase-13 (collagenase 3) [EC:3.4.24.-]
Pathway
map04657
IL-17 signaling pathway
map04926
Relaxin signaling pathway
map04928
Parathyroid hormone synthesis, secretion and action
Disease
H00479
Metaphyseal dysplasias
H02187
Spondyloepimetaphyseal dysplasia
Brite
KEGG Orthology (KO) [BR:
ko00001
]
09150 Organismal Systems
09151 Immune system
04657 IL-17 signaling pathway
K07994 MMP13; matrix metalloproteinase-13 (collagenase 3)
09152 Endocrine system
04926 Relaxin signaling pathway
K07994 MMP13; matrix metalloproteinase-13 (collagenase 3)
04928 Parathyroid hormone synthesis, secretion and action
K07994 MMP13; matrix metalloproteinase-13 (collagenase 3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors
K07994 MMP13; matrix metalloproteinase-13 (collagenase 3)
Peptidases and inhibitors [BR:
ko01002
]
Metallo peptidases
Family M10
K07994 MMP13; matrix metalloproteinase-13 (collagenase 3)
BRITE hierarchy
Genes
HSA:
4322
(MMP13)
PTR:
451513
(MMP13)
PPS:
100994591
(MMP13)
GGO:
101133827
(MMP13)
PON:
103888514
(MMP13)
PPYG:
129007823
(MMP13)
NLE:
100584961
(MMP13)
HMH:
116477423
(MMP13)
SSYN:
129479564
(MMP13)
MCC:
703980
(MMP13)
MCF:
102144082
(MMP13)
MTHB:
126935447
MNI:
105493702
(MMP13)
CSAB:
103248347
(MMP13)
CATY:
105588768
(MMP13)
PANU:
101002189
(MMP13)
TGE:
112606431
(MMP13)
MLEU:
105542747
(MMP13)
RRO:
104674670
(MMP13)
RBB:
108514066
(MMP13)
TFN:
117079909
(MMP13)
PTEH:
111540074
(MMP13)
CANG:
105500948
(MMP13)
CJC:
100396943
(MMP13)
SBQ:
101050615
(MMP13)
CIMI:
108315433
(MMP13)
ANAN:
105719542
(MMP13)
CSYR:
103260632
(MMP13)
MMUR:
105874591
(MMP13)
LCAT:
123641000
(MMP13)
PCOQ:
105822160
(MMP13)
OGA:
100952543
(MMP13)
MMU:
17386
(Mmp13)
MCAL:
110301676
(Mmp13)
MPAH:
110327961
(Mmp13)
RNO:
171052
(Mmp13)
MCOC:
116072138
(Mmp13)
ANU:
117699975
(Mmp13)
MUN:
110558087
(Mmp13)
CGE:
100759377
(Mmp13)
MAUA:
101823919
(Mmp13)
PROB:
127232929
(Mmp13)
PLEU:
114708023
(Mmp13)
MORG:
121451801
(Mmp13)
MFOT:
126493292
AAMP:
119810342
(Mmp13)
NGI:
103731596
(Mmp13)
HGL:
101699013
(Mmp13)
CPOC:
100731756
(Mmp13)
CCAN:
109689283
(Mmp13)
DORD:
105980666
(Mmp13)
DSP:
122110309
(Mmp13)
PLOP:
125348067
(Mmp13)
NCAR:
124960055
MMMA:
107145999
(Mmp13)
OCU:
100008685
(MMP13)
OPI:
101527896
TUP:
102488239
(MMP13)
GVR:
103600375
(MMP13)
CFA:
403763
(MMP13)
CLUD:
112671435
(MMP13)
VVP:
112925938
(MMP13)
VLG:
121500393
(MMP13)
NPO:
129497416
(MMP13)
AML:
100478671
(MMP13)
UMR:
103662450
(MMP13)
UAH:
113260133
(MMP13)
UAR:
123792505
(MMP13)
ELK:
111153761
LLV:
125079958
MPUF:
101687929
(MMP13)
MNP:
132013246
(MMP13)
MLK:
131834673
(MMP13)
NVS:
122913957
(MMP13)
ORO:
101368693
(MMP13)
EJU:
114211385
(MMP13)
ZCA:
113914517
(MMP13)
MLX:
118013058
(MMP13)
NSU:
110586243
(MMP13)
LWW:
102733693
(MMP13)
FCA:
493679
(MMP13)
PYU:
121020772
(MMP13)
PCOO:
112866154
(MMP13)
PBG:
122482893
(MMP13)
PVIV:
125175965
(MMP13)
LRUF:
124505582
PTG:
102969710
(MMP13)
PPAD:
109257531
(MMP13)
PUC:
125910747
AJU:
106976506
HHV:
120223086
(MMP13)
BTA:
281914
(MMP13)
BOM:
102288041
(MMP13)
BIU:
109568743
(MMP13)
BBUB:
102413613
(MMP13)
BBIS:
104987811
(MMP13)
CHX:
102170069
(MMP13)
OAS:
443113
(MMP13)
BTAX:
128060461
(MMP13)
ODA:
120876146
(MMP13)
CCAD:
122449996
(MMP13)
MBEZ:
129553536
(MMP13)
SSC:
397346
(MMP13)
CFR:
102516544
(MMP13)
CBAI:
105067592
(MMP13)
CDK:
105087166
(MMP13)
VPC:
102527929
(MMP13)
BACU:
103010343
(MMP13)
BMUS:
118899400
(MMP13)
LVE:
103089578
(MMP13)
OOR:
101270492
(MMP13)
DLE:
111167571
PCAD:
102983217
(MMP13)
PSIU:
116757942
(MMP13)
NASI:
112415748
(MMP13)
ECB:
100009711
(MMP13)
EPZ:
103561913
(MMP13)
EAI:
106843119
(MMP13)
MYD:
102769947
(MMP13)
MMYO:
118664457
(MMP13)
MLF:
102427353
102431911
MDT:
132240618
(MMP13)
PKL:
118713359
(MMP13)
EFUS:
103292969
(MMP13)
MNA:
107532385
(MMP13)
DRO:
112317542
(MMP13)
SHON:
118975696
(MMP13)
AJM:
119046925
(MMP13)
PDIC:
114500088
(MMP13)
PHAS:
123805472
(MMP13)
MMF:
118628046
(MMP13)
PPAM:
129086167
(MMP13)
RFQ:
117030437
(MMP13)
PALE:
102886632
(MMP13)
PGIG:
120599659
(MMP13)
PVP:
105297439
(MMP13)
RAY:
107504653
(MMP13)
MJV:
108391133
(MMP13)
TOD:
119239978
(MMP13)
SARA:
101544591
(MMP13)
SETR:
126016079
(MMP13)
LAV:
100660883
(MMP13)
TMU:
101340756
ETF:
101654942
101655679
(MMP13)
DNM:
101412853
(MMP13)
MDO:
100012553
(MMP13)
GAS:
123238996
(MMP13)
SHR:
100915582
(MMP13)
AFZ:
127554927
PCW:
110214933
(MMP13)
TVP:
118838145
(MMP13)
OAA:
100078875
100078901
GGA:
395683
(MMP13)
PCOC:
116230617
CJO:
107308401
TPAI:
128074809
LMUT:
125695520
NMEL:
110389854
APLA:
101794528
ACYG:
106034120
CATA:
118245926
AFUL:
116502332
TGU:
100217703
LSR:
110470056
SCAN:
103827286
PMOA:
120506626
OTC:
121342527
PRUF:
121364178
GFR:
102045050
(MMP13)
FAB:
101806016
(MMP13)
OMA:
130251554
PHI:
102111493
PMAJ:
107204357
CCAE:
111924318
CCW:
104690060
CBRC:
103617948
ETL:
114067047
ZAB:
102069627
ZLE:
135457592
ACHL:
103811759
(MMP13)
SVG:
106859370
MMEA:
130576289
HRT:
120748575
SATI:
136357574
FPG:
101924923
(MMP13)
FCH:
102050771
CCRI:
104156255
(MMP13)
NNT:
104406825
(MMP13)
SHAB:
115603853
ACUN:
113477002
TALA:
104362839
ACHC:
115353593
HALD:
104314244
(MMP13)
HLE:
104828447
(MMP13)
AGEN:
126048147
GCL:
127018223
CSTI:
104556372
LDI:
104347142
(MMP13)
MNB:
103768527
(MMP13)
DPUB:
104296912
(MMP13)
AVIT:
104267156
(MMP13)
BRHI:
104489344
(MMP13)
EGZ:
104128903
NNI:
104023067
PCRI:
104025921
(MMP13)
PCAO:
104045334
(MMP13)
PADL:
103915450
AFOR:
103895108
FGA:
104082506
(MMP13)
GSTE:
104251887
(MMP13)
CLV:
102089243
MUI:
104537559
(MMP13)
PGUU:
104459490
(MMP13)
PLET:
104617750
(MMP13)
EHS:
104503919
(MMP13)
CMAC:
104485073
(MMP13)
CUCA:
104064702
TEO:
104382170
(MMP13)
BREG:
104633764
OHA:
104333035
ACAR:
104522623
CPEA:
104390274
CVF:
104290310
RTD:
128914369
AAM:
106495501
AROW:
112971958
NPD:
112943712
TGT:
104571782
(MMP13)
DNE:
112988756
SCAM:
104151758
(MMP13)
ASN:
102380725
AMJ:
102567734
(MMP13)
CPOO:
109306731
GGN:
109303409
PSS:
102447259
(MMP13)
CMY:
102940155
CCAY:
125633976
DCC:
119858204
CPIC:
101949768
TST:
117871169
CABI:
116837661
MRV:
120395453
(MMP13)
ACS:
100552256
(mmp13)
ASAO:
132772195
PVT:
110089075
SUND:
121925183
121926849
PBI:
103059603
103067176
PMUR:
107286360
107286367
CTIG:
120313880
120313883
TSR:
106544080
106544084
PGUT:
117660875
117663932
APRI:
131199400
131200055
PTEX:
113440405
113440481
NSS:
113417306
113417323
VKO:
123029181
123029251
PMUA:
114595665
PRAF:
128412590
ZVI:
118085534
HCG:
128350838
128352361
GJA:
107119160
STOW:
125431541
125431543
125431963
EMC:
129325830
129326302
XLA:
108709982
379369
(mmp7.L)
379552
(MGC68994)
379564
(mmp13.S)
397823
(mmp13l.L)
398056
(mmp13l.S)
XTR:
100489108
100490019
(mmp13l)
101731804
116408605
116408897
448575
(mmp7)
613098
(mmp13)
NPR:
108786931
108795958
108795959
108795961
RTEM:
120928205
120929028
120929029
120929030
120929031
120929040
BBUF:
120994011
120996395
120996400
120996402
BGAR:
122930904
122931167
122931326
122931358
MUO:
115467866
(MMP7)
115467869
115469592
GSH:
117362380
117362383
117362703
(MMP7)
DRE:
100006896
(mmp13b)
SRX:
107730823
(mmp13)
107743428
107743466
107743483
107758590
107758621
107758623
SANH:
107653688
107653699
107653700
107679505
107679523
107680321
107683448
(mmp13)
SGH:
107565251
107565252
107565253
107570350
107582278
107583420
107583435
107583436
CCAR:
109049256
109049259
109049263
109049493
109060460
109060466
109060721
CAUA:
113053906
113053908
113054505
113054506
113058598
113059025
113069599
113069600
113110012
113110013
CGIB:
127965938
128020970
128020978
128021525
128028628
PTET:
122331835
122331836
122358574
(mmp13b)
LROH:
127159418
127159419
127172466
127172467
127177394
(mmp13b)
OMC:
131537583
131548385
131548386
131554257
(mmp13b)
PPRM:
120478831
(mmp13b)
120483227
120483228
RKG:
130078786
130078958
130104350
(mmp13b)
MAMB:
125249640
(mmp13b)
125262253
(mmp13a)
125262254
125262255
CIDE:
127496229
127521216
127521219
CERY:
137004683
(mmp13b)
137028326
137028606
MASI:
127422068
127432428
TROS:
130546334
130565240
(mmp13b)
TDW:
130411905
130428433
(mmp13b)
MANU:
129437365
(mmp13b)
IPU:
100526826
(mmp13)
108276914
108276915
108276916
108277431
(mmp13b)
IFU:
128620325
128621773
(mmp13b)
PHYP:
113539152
113544715
113544717
113544733
113544739
113544865
SMEO:
124393966
124394698
(mmp13b)
TFD:
113645257
(mmp13b)
113650205
113650236
TVC:
132857773
(mmp13b)
132863436
TRN:
134334222
(mmp13b)
AMEX:
103036002
(mmp13b)
103038343
103038651
103041846
111195015
CMAO:
118796781
(mmp13b)
118824747
EEE:
113580711
113580721
113580723
113582458
CHAR:
105901353
(mmp13b)
105904454
(mmp13a)
122129513
TRU:
101066804
(mmp13)
101074218
(mmpf1)
115246417
TFS:
130534785
(mmp13b)
130537202
TNG:
GSTEN00004922G001
GSTEN00005277G001
GSTEN00010534G001
LCO:
104930325
104940508
(mmp13)
109137323
109137325
NCC:
104951202
104958449
104961222
TBEN:
117468624
117468633
117468646
117470184
(mmp13b)
CGOB:
115017703
115018842
115018870
115018871
PGEO:
117457490
(mmp13b)
117458246
117458247
(mmp13a)
117458248
117458251
GACU:
117551706
117551748
117553038
117553040
117553041
EMAC:
134871928
134871929
134879896
ELY:
117260054
(mmp13b)
117271738
EFO:
125888814
(mmp13b)
125897981
PLEP:
121943346
(mmp13b)
121952849
SLUC:
116046519
(mmp13b)
116058151
116058152
116058153
116058154
ECRA:
117939516
(mmp13b)
117955247
117955249
ESP:
116687148
116700829
PFLV:
114552539
(mmp13)
114566697
114566802
114566803
114567151
GAT:
120822795
120826473
(mmp13b)
PPUG:
119214292
(mmp13b)
119215383
119215412
119215413
119215416
119215915
AFB:
129090978
(mmp13b)
129114046
(mmp13a)
CLUM:
117741716
(mmp13b)
117742356
(mmp13a)
PSWI:
130210783
(mmp13b)
MSAM:
119882335
(mmp13b)
119885379
119885380
119894759
119895698
119895700
119895701
119895927
119896105
119896167
SCHU:
122878670
122888377
(mmp13a)
122888378
CUD:
121518500
121518501
121518502
121518657
121518658
121518842
(mmp13a)
121524290
(mmp13b)
ALAT:
119006632
(mmp13b)
119031230
119031844
(mmp13a)
119031845
MZE:
101478797
101479082
101485790
(mmp13)
106674904
ONL:
100703220
100707792
(mmp13)
100711125
100711395
100711668
109203849
OAU:
116332788
(mmp13a)
116332796
116332799
116334917
(mmp13b)
120442346
OLA:
100049293
(coll)
101156669
101159886
OML:
112141134
112141141
112149560
(mmp13b)
CSAI:
133442260
(mmp13b)
133459872
(mmp13a)
XMA:
102217363
102233475
102236177
111610002
111610113
XCO:
114152677
114153710
114153711
114153712
114161342
XHE:
116728569
116728570
116728571
116729023
116729024
116737221
PRET:
103461519
103474778
108166865
PFOR:
103129780
103131708
103132926
103145369
PLAI:
106935241
106951556
106951597
106951598
PMEI:
106906143
106907731
106907733
106926287
106926288
GAF:
122832330
(mmp13b)
122844778
122845023
122845024
122845026
PPRL:
129359103
(mmp13b)
129370581
(mmp13a)
CVG:
107083472
107091373
CTUL:
119771820
(mmp13b)
119788057
119788060
GMU:
124875995
124876487
124884234
(mmp13b)
NFU:
107380717
(mmp13)
107386542
KMR:
108238146
(mmp13b)
108247969
108247974
ALIM:
106525662
106526501
106526514
NWH:
119411176
(mmp13b)
119420230
119420726
AOCE:
111569179
(mmp13)
111583608
111583609
111583610
MCEP:
125013571
(mmp13b)
125021843
125021844
125021845
125021847
125021849
125021850
125021852
125021853
CSEM:
103377666
103394800
103394801
POV:
109628329
109628434
109634449
SSEN:
122773088
122780194
122780195
HHIP:
117772330
(mmp13b)
117774303
117774304
117774305
117774306
117774640
HSP:
118106257
(mmp13b)
118121992
(mmp13a)
118121993
118121994
PPLT:
128440233
(mmp13b)
128456887
SMAU:
118299803
(mmp13b)
118301206
118301207
LCF:
108893138
108893262
108894065
(mmp13a)
108898845
(mmp13b)
SDU:
111222178
111222300
111222301
111233402
(mmp13)
SLAL:
111663530
111663531
111665438
(mmp13)
XGL:
120791998
(mmp13b)
120802389
120802390
120802391
HCQ:
109512889
(mmp13)
109531162
109531163
SSCV:
125972859
125982671
125982685
SBIA:
133492032
133504669
(mmp13b)
PEE:
133404876
(mmp13b)
133415844
PTAO:
133467023
133482703
(mmp13b)
BPEC:
110161929
(mmp13)
110169007
110169013
110169016
110169096
MALB:
109960358
(mmp13)
109972871
109972890
BSPL:
114868595
(mmp13b)
114869183
114869185
SJO:
128360310
(mmp13b)
128370843
SASA:
100136348
100195495
(mmp13)
106567924
106581219
106613110
STRU:
115148916
115154375
115163560
115206460
OTW:
112228595
112257809
112265628
112267198
OMY:
100135803
(mmp)
100136017
110507873
(mmp13b)
OGO:
123993906
124000314
124006442
124010222
ONE:
115104679
115135872
115136652
115141922
OKI:
109872935
109892118
109906097
109909707
OKE:
118390116
118394897
118397535
SALP:
111950692
111960703
111981523
111982623
SNH:
120018858
120029020
120044313
120057088
CCLU:
121567029
121568344
121574328
121574329
121579795
121579796
ELS:
105005971
105005972
105008444
105009335
105010505
105023807
(mmp13)
105030494
106023916
109615890
114828688
114833804
114839302
SFM:
108921331
108921509
108921532
108932197
108932305
114909087
PKI:
111844842
111860877
111860878
AANG:
118209207
(mmp13b)
118234926
118235358
LOC:
102684784
102692873
(mmp13)
PSPA:
121302619
(mmp13b)
121302833
121320395
ARUT:
117402261
117405119
117405366
117406119
117971219
117973054
PSEX:
120523305
120523306
120523307
120523313
120523314
120523315
120523316
120523317
(mmp13b)
LCM:
102359698
102359959
102360231
102360492
102361009
CMK:
103177581
(mmp13b)
103177584
RTP:
109928526
109936741
CPLA:
122550423
122550687
122551025
HOC:
132816338
132816610
132816756
LERI:
129698148
129698297
129716256
129716258
PMRN:
116950204
LRJ:
133348867
BBEL:
109483262
LPIC:
129269647
ARUN:
117292131
AJC:
117110049
BCOO:
119072402
NLO:
107219945
DVV:
126891206
PPYR:
116163037
116164204
116169129
DCI:
103523648
TPAL:
117640117
GAE:
121368721
ATEN:
116289243
PDAM:
113678765
113678772
HSY:
130625852
130628545
PARJ:
J4G78_04600
» show all
Taxonomy
UniProt
Reference
PMID:
8207000
Authors
Freije JM, Diez-Itza I, Balbin M, Sanchez LM, Blasco R, Tolivia J, Lopez-Otin C
Title
Molecular cloning and expression of collagenase-3, a novel human matrix metalloproteinase produced by breast carcinomas.
Journal
J Biol Chem 269:16766-73 (1994)
Sequence
[hsa:
4322
]
LinkDB
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DBGET
integrated database retrieval system