Entry
Name
Neuroactive ligand signaling - Oncorhynchus kisutch (coho salmon)
Description
Neuroactive ligand signaling is a process where receptors and ligands on the cell membrane initiate intracellular signaling pathways. It plays a crucial role in the development of various brain disorders.
Class
Environmental Information Processing; Signaling molecules and interaction
BRITE hierarchy
Pathway map
Organism
Oncorhynchus kisutch (coho salmon) [GN:
oki ]
Gene
109866053 gng4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 [KO:K04541 ]
109866544 gabrr1; gamma-aminobutyric acid receptor subunit rho-1 [KO:K05190 ]
109867359 slc1a2; excitatory amino acid transporter 2 isoform X1 [KO:K05613 ]
109869198 gnas; guanine nucleotide-binding protein G(s) subunit alpha [KO:K04632 ]
109873735 gng3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 [KO:K04540 ]
109880394 gng10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 [KO:K04545 ]
109882671 slc6a1; sodium- and chloride-dependent GABA transporter 1 [KO:K05034 ]
109882921 slc6a11; sodium- and chloride-dependent GABA transporter 3 [KO:K05044 ]
109896842 plcb3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 isoform X1 [KO:K05858 ] [EC:3.1.4.11 ]
109900392 plcb4; LOW QUALITY PROTEIN: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 [KO:K05858 ] [EC:3.1.4.11 ]
109902263 gnb4; guanine nucleotide-binding protein subunit beta-4 [KO:K04538 ]
109905347 gpr171; probable G-protein coupled receptor 171 isoform X2 [KO:K04299 ]
Compound
C16103 Agouti related protein (87-132)
Reference
Authors
Nimgampalle M, Chakravarthy H, Sharma S, Shree S, Bhat AR, Pradeepkiran JA, Devanathan V
Title
Neurotransmitter systems in the etiology of major neurological disorders: Emerging insights and therapeutic implications.
Journal
Reference
Authors
Malik AR, Willnow TE
Title
Excitatory Amino Acid Transporters in Physiology and Disorders of the Central Nervous System.
Journal
Reference
Authors
Higley MJ
Title
Localized GABAergic inhibition of dendritic Ca(2+) signalling.
Journal
Reference
Authors
Brambilla P, Perez J, Barale F, Schettini G, Soares JC
Title
GABAergic dysfunction in mood disorders.
Journal
Reference
Authors
Shimizu-Okabe C, Kobayashi S, Kim J, Kosaka Y, Sunagawa M, Okabe A, Takayama C
Title
Developmental Formation of the GABAergic and Glycinergic Networks in the Mouse Spinal Cord.
Journal
Reference
Authors
Wang Y, Tan B, Wang Y, Chen Z
Title
Cholinergic Signaling, Neural Excitability, and Epilepsy.
Journal
Reference
Authors
Channer B, Matt SM, Nickoloff-Bybel EA, Pappa V, Agarwal Y, Wickman J, Gaskill PJ
Title
Dopamine, Immunity, and Disease.
Journal
Reference
Authors
Savica R, Benarroch EE
Title
Dopamine receptor signaling in the forebrain: recent insights and clinical implications.
Journal
Reference
Authors
Pourhamzeh M, Moravej FG, Arabi M, Shahriari E, Mehrabi S, Ward R, Ahadi R, Joghataei MT
Title
The Roles of Serotonin in Neuropsychiatric Disorders.
Journal
Reference
Authors
Chhatar S, Lal G
Title
Role of adrenergic receptor signalling in neuroimmune communication.
Journal
Reference
Authors
Szukiewicz D
Title
Histaminergic System Activity in the Central Nervous System: The Role in Neurodevelopmental and Neurodegenerative Disorders.
Journal
Reference
Authors
Huang Z, Xie N, Illes P, Di Virgilio F, Ulrich H, Semyanov A, Verkhratsky A, Sperlagh B, Yu SG, Huang C, Tang Y
Title
From purines to purinergic signalling: molecular functions and human diseases.
Journal
Reference
Authors
Fields RD, Burnstock G
Title
Purinergic signalling in neuron-glia interactions.
Journal
Reference
Authors
Cawley NX, Li Z, Loh YP
Title
60 YEARS OF POMC: Biosynthesis, trafficking, and secretion of pro-opiomelanocortin-derived peptides.
Journal
Reference
Authors
Butler AA, Girardet C, Mavrikaki M, Trevaskis JL, Macarthur H, Marks DL, Farr SA
Title
A Life without Hunger: The Ups (and Downs) to Modulating Melanocortin-3 Receptor Signaling.
Journal
Reference
Authors
Toll L, Bruchas MR, Calo' G, Cox BM, Zaveri NT
Title
Nociceptin/Orphanin FQ Receptor Structure, Signaling, Ligands, Functions, and Interactions with Opioid Systems.
Journal
Reference
Authors
Campo A, Dufour S, Rousseau K
Title
Tachykinins, new players in the control of reproduction and food intake: A comparative review in mammals and teleosts.
Journal
Related pathway
oki04080 Neuroactive ligand-receptor interaction
KO pathway