Entry |
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Name |
Regulation of actin cytoskeleton - Cervus canadensis (wapiti) |
Class |
Cellular Processes; Cell motility
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Pathway map |
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Other DBs |
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Organism |
Cervus canadensis (wapiti) [GN: ccad]
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Gene |
122422171 | EGF; LOW QUALITY PROTEIN: pro-epidermal growth factor [KO:K04357] |
122433132 | PDGFA; platelet-derived growth factor subunit A isoform X1 [KO:K04359] |
122432743 | GNA12; guanine nucleotide-binding protein subunit alpha-12 isoform X1 [KO:K04346] |
122426182 | GNA13; guanine nucleotide-binding protein subunit alpha-13 [KO:K04639] |
122435562 | FGD1; FYVE, RhoGEF and PH domain-containing protein 1 [KO:K05720] |
122431744 | FGD3; FYVE, RhoGEF and PH domain-containing protein 3 isoform X1 [KO:K05722] |
122421110 | BCAR1; breast cancer anti-estrogen resistance protein 1 isoform X1 [KO:K05726] |
122436027 | ARHGEF6; rho guanine nucleotide exchange factor 6 isoform X1 [KO:K05729] |
122451688 | PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1 [KO:K00922] [EC:2.7.1.153] |
122444906 | PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153] |
122440740 | PIK3R2; LOW QUALITY PROTEIN: phosphatidylinositol 3-kinase regulatory subunit beta [KO:K02649] |
122454626 | PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649] |
122437038 | PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1 [KO:K02649] |
122442367 | VAV2; guanine nucleotide exchange factor VAV2 isoform X1 [KO:K05730] |
122428727 | TIAM1; rho guanine nucleotide exchange factor TIAM1 isoform X1 [KO:K05731] |
122446062 | LOW QUALITY PROTEIN: dual specificity mitogen-activated protein kinase kinase 2-like [KO:K04369] [EC:2.7.12.2] |
122420164 | ARHGEF1; rho guanine nucleotide exchange factor 1 isoform X1 [KO:K12330] |
122450130 | ARHGEF12; rho guanine nucleotide exchange factor 12 isoform X1 [KO:K07532] |
122433321 | RAC1; ras-related C3 botulinum toxin substrate 1 isoform X1 [KO:K04392] |
122426807 | CDC42; cell division control protein 42 homolog isoform X1 [KO:K04393] |
122447533 | ARHGEF7; rho guanine nucleotide exchange factor 7 isoform X1 [KO:K13710] |
122427569 | PPP1R12A; protein phosphatase 1 regulatory subunit 12A isoform X1 [KO:K06270] |
122452339 | PPP1R12B; protein phosphatase 1 regulatory subunit 12B isoform X1 [KO:K12329] |
122420802 | PPP1R12C; protein phosphatase 1 regulatory subunit 12C isoform X1 [KO:K17457] |
122423562 | MYL2; myosin regulatory light chain 2, ventricular/cardiac muscle isoform [KO:K10351] |
122438532 | MYL7; myosin regulatory light chain 2, atrial isoform [KO:K12754] |
122437006 | myosin regulatory light chain 2, smooth muscle major isoform-like isoform X1 [KO:K12755] |
122432784 | MYLPF; myosin regulatory light chain 2, skeletal muscle isoform [KO:K12758] |
122438249 | BAIAP2; brain-specific angiogenesis inhibitor 1-associated protein 2 isoform X1 [KO:K05627] |
122438593 | WASL; neural Wiskott-Aldrich syndrome protein isoform X1 [KO:K23612] |
122426073 | WASF2; wiskott-Aldrich syndrome protein family member 2 [KO:K05748] |
122439633 | CYFIP2; cytoplasmic FMR1-interacting protein 2 isoform X1 [KO:K05749] |
122453733 | CYFIP1; cytoplasmic FMR1-interacting protein 1 isoform X1 [KO:K05749] |
122422652 | WASF1; wiskott-Aldrich syndrome protein family member 1 isoform X1 [KO:K05753] |
122441667 | LOW QUALITY PROTEIN: actin-related protein 2/3 complex subunit 1A-like [KO:K05757] |
122442158 | ARPC5L; actin-related protein 2/3 complex subunit 5-like protein [KO:K05754] |
122452100 | ARPC5; actin-related protein 2/3 complex subunit 5 isoform X1 [KO:K05754] |
122442987 | IQGAP2; ras GTPase-activating-like protein IQGAP2 isoform X1 [KO:K05767] |
122432024 | IQGAP3; ras GTPase-activating-like protein IQGAP3 isoform X1 [KO:K05767] |
122439955 | APC2; adenomatous polyposis coli protein 2 isoform X1 [KO:K02085] |
122447183 | SPATA13; spermatogenesis-associated protein 13 isoform X1 [KO:K05769] |
122453544 | ARHGEF4; rho guanine nucleotide exchange factor 4 isoform X1 [KO:K05769] |
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Compound |
C00681 | 1-Acyl-sn-glycerol 3-phosphate |
C04637 | 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate |
C05981 | Phosphatidylinositol-3,4,5-trisphosphate |
C11554 | 1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate |
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Reference |
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Authors |
Burridge K, Wennerberg K. |
Title |
Rho and Rac take center stage. |
Journal |
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Reference |
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Authors |
Schmitz AA, Govek EE, Bottner B, Van Aelst L. |
Title |
Rho GTPases: signaling, migration, and invasion. |
Journal |
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Reference |
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Authors |
Takai Y, Sasaki T, Matozaki T. |
Title |
Small GTP-binding proteins. |
Journal |
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Reference |
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Authors |
Pollard TD. |
Title |
The cytoskeleton, cellular motility and the reductionist agenda. |
Journal |
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Reference |
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Authors |
Ridley AJ, Schwartz MA, Burridge K, Firtel RA, Ginsberg MH, Borisy G, Parsons JT, Horwitz AR. |
Title |
Cell migration: integrating signals from front to back. |
Journal |
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Reference |
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Authors |
Sastry SK, Burridge K. |
Title |
Focal adhesions: a nexus for intracellular signaling and cytoskeletal dynamics. |
Journal |
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Reference |
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Authors |
Fukata M, Nakagawa M, Kuroda S, Kaibuchi K. |
Title |
Cell adhesion and Rho small GTPases. |
Journal |
J Cell Sci 112 ( Pt 24):4491-500 (1999) |
Related pathway |
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KO pathway |
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LinkDB |
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