Entry |
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Name |
Regulation of actin cytoskeleton - Ovis aries (sheep) |
Class |
Cellular Processes; Cell motility
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Pathway map |
oas04810 | Regulation of actin cytoskeleton |
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Other DBs |
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Organism |
Ovis aries (sheep) [GN: oas]
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Gene |
101104572 | LPAR2; LOW QUALITY PROTEIN: lysophosphatidic acid receptor 2 [KO:K04291] |
443306 | FGF2; fibroblast growth factor 2 precursor [KO:K18497] |
443074 | FGF10; fibroblast growth factor 10 precursor [KO:K04358] |
114110564 | PDGFA; platelet-derived growth factor subunit A isoform X2 [KO:K04359] |
443545 | PDGFB; platelet-derived growth factor subunit B precursor [KO:K17386] |
443189 | CHRM3; muscarinic acetylcholine receptor M3 isoform X1 [KO:K04131] |
101111070 | GNA12; guanine nucleotide-binding protein subunit alpha-12 isoform X1 [KO:K04346] |
101117003 | GNA13; guanine nucleotide-binding protein subunit alpha-13 [KO:K04639] |
106991180 | GNG14; putative guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-14 [KO:K04347] |
101115838 | GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 [KO:K04347] |
101117050 | FGD1; FYVE, RhoGEF and PH domain-containing protein 1 isoform X1 [KO:K05720] |
101107664 | FGD3; FYVE, RhoGEF and PH domain-containing protein 3 isoform X7 [KO:K05722] |
101117693 | BCAR1; breast cancer anti-estrogen resistance protein 1 isoform X1 [KO:K05726] |
101104043 | ARHGEF6; rho guanine nucleotide exchange factor 6 isoform X1 [KO:K05729] |
101109759 | PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153] |
101110015 | PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153] |
101117348 | PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X3 [KO:K00922] [EC:2.7.1.153] |
101123247 | PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1 [KO:K02649] |
101111546 | PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta isoform X2 [KO:K02649] |
101121455 | PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X3 [KO:K02649] |
101120709 | VAV3; guanine nucleotide exchange factor VAV3 isoform X5 [KO:K05730] |
101110137 | VAV2; guanine nucleotide exchange factor VAV2 isoform X1 [KO:K05730] |
101103280 | TIAM1; rho guanine nucleotide exchange factor TIAM1 isoform X1 [KO:K05731] |
101104265 | ARHGEF1; rho guanine nucleotide exchange factor 1 isoform X4 [KO:K12330] |
101117190 | ARHGEF12; rho guanine nucleotide exchange factor 12 isoform X2 [KO:K07532] |
101117354 | ARHGAP35; rho GTPase-activating protein 35 isoform X1 [KO:K05732] |
101107592 | RAC2; ras-related C3 botulinum toxin substrate 2 isoform X2 [KO:K07860] |
101112406 | RAC3; ras-related C3 botulinum toxin substrate 3 isoform X2 [KO:K07861] |
101116845 | ARHGEF7; rho guanine nucleotide exchange factor 7 isoform X1 [KO:K13710] |
641303 | PPP1R12A; protein phosphatase 1 regulatory subunit 12A isoform X5 [KO:K06270] |
101114596 | PPP1R12B; protein phosphatase 1 regulatory subunit 12B isoform X4 [KO:K12329] |
101122546 | PPP1R12C; protein phosphatase 1 regulatory subunit 12C isoform X1 [KO:K17457] |
100196904 | MYL2; myosin regulatory light chain 2, ventricular/cardiac muscle isoform [KO:K10351] |
101117156 | MYL7; myosin regulatory light chain 2, atrial isoform isoform X1 [KO:K12754] |
494435 | SLC9A1; sodium/hydrogen exchanger 1 isoform X1 [KO:K05742] |
101109895 | BAIAP2; brain-specific angiogenesis inhibitor 1-associated protein 2 isoform X1 [KO:K05627] |
101106932 | WASL; actin nucleation-promoting factor WASL isoform X1 [KO:K23612] |
101120599 | LOW QUALITY PROTEIN: actin-binding protein WASF2-like [KO:K05748] |
100188913 | CYFIP1; LOW QUALITY PROTEIN: cytoplasmic FMR1-interacting protein 1 [KO:K05749] |
101113558 | ARPC1B; actin-related protein 2/3 complex subunit 1B isoform X2 [KO:K05757] |
101105166 | LOW QUALITY PROTEIN: actin-related protein 2/3 complex subunit 1A-like [KO:K05757] |
101105028 | ARPC3; actin-related protein 2/3 complex subunit 3 isoform X2 [KO:K05756] |
105601868 | ARPC4; actin-related protein 2/3 complex subunit 4 isoform X2 [KO:K05755] |
100037671 | ARPC5L; actin-related protein 2/3 complex subunit 5-like protein [KO:K05754] |
101108447 | IQGAP3; ras GTPase-activating-like protein IQGAP3 isoform X1 [KO:K05767] |
101115458 | APC2; adenomatous polyposis coli protein 2 isoform X1 [KO:K02085] |
101104720 | ARHGEF4; LOW QUALITY PROTEIN: rho guanine nucleotide exchange factor 4 [KO:K05769] |
101116156 | SPATA13; spermatogenesis-associated protein 13 isoform X5 [KO:K05769] |
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Compound |
C00681 | 1-Acyl-sn-glycerol 3-phosphate |
C04637 | 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate |
C05981 | Phosphatidylinositol-3,4,5-trisphosphate |
C11554 | 1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate |
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Reference |
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Authors |
Burridge K, Wennerberg K. |
Title |
Rho and Rac take center stage. |
Journal |
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Reference |
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Authors |
Schmitz AA, Govek EE, Bottner B, Van Aelst L. |
Title |
Rho GTPases: signaling, migration, and invasion. |
Journal |
|
Reference |
|
Authors |
Takai Y, Sasaki T, Matozaki T. |
Title |
Small GTP-binding proteins. |
Journal |
|
Reference |
|
Authors |
Pollard TD. |
Title |
The cytoskeleton, cellular motility and the reductionist agenda. |
Journal |
|
Reference |
|
Authors |
Ridley AJ, Schwartz MA, Burridge K, Firtel RA, Ginsberg MH, Borisy G, Parsons JT, Horwitz AR. |
Title |
Cell migration: integrating signals from front to back. |
Journal |
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Reference |
|
Authors |
Sastry SK, Burridge K. |
Title |
Focal adhesions: a nexus for intracellular signaling and cytoskeletal dynamics. |
Journal |
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Reference |
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Authors |
Fukata M, Nakagawa M, Kuroda S, Kaibuchi K. |
Title |
Cell adhesion and Rho small GTPases. |
Journal |
J Cell Sci 112 ( Pt 24):4491-500 (1999) |
Related pathway |
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KO pathway |
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LinkDB |
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