KEGG   PATHWAY: umr04024
Entry
umr04024                    Pathway                                
Name
cAMP signaling pathway - Ursus maritimus (polar bear)
Description
cAMP is one of the most common and universal second messengers, and its formation is promoted by adenylyl cyclase (AC) activation after ligation of G protein-coupled receptors (GPCRs) by ligands including hormones, neurotransmitters, and other signaling molecules. cAMP regulates pivotal physiologic processes including metabolism, secretion, calcium homeostasis, muscle contraction, cell fate, and gene transcription. cAMP acts directly on three main targets: protein kinase A (PKA), the exchange protein activated by cAMP (Epac), and cyclic nucleotide-gated ion channels (CNGCs). PKA modulates, via phosphorylation, a number of cellular substrates, including transcription factors, ion channels, transporters, exchangers, intracellular Ca2+ -handling proteins, and the contractile machinery. Epac proteins function as guanine nucleotide exchange factors (GEFs) for both Rap1 and Rap2. Various effector proteins, including adaptor proteins implicated in modulation of the actin cytoskeleton, regulators of G proteins of the Rho family, and phospholipases, relay signaling downstream from Rap.
Class
Environmental Information Processing; Signal transduction
Pathway map
umr04024  cAMP signaling pathway
umr04024

Other DBs
GO: 0019933
Organism
Ursus maritimus (polar bear) [GN:umr]
Gene
103666900  VIP peptides [KO:K05264]
103677518  CRH; corticoliberin [KO:K05256]
103659748  CGA; glycoprotein hormones alpha chain [KO:K08522]
103657111  lutropin subunit beta [KO:K08521]
103672403  GPHB5; glycoprotein hormone beta-5 [KO:K25484]
103669418  TSHB; thyrotropin subunit beta [KO:K05251]
121101079  POMC; pro-opiomelanocortin [KO:K05228]
103659505  GCG; pro-glucagon [KO:K05259]
103661039  gastric inhibitory polypeptide [KO:K05258]
103659360  follitropin subunit beta [KO:K05250]
103666859  NPPA; natriuretic peptides A [KO:K12334]
103662738  ADCYAP1; pituitary adenylate cyclase-activating polypeptide isoform X1 [KO:K05262]
121101313  ADRB1; beta-1 adrenergic receptor [KO:K04141]
103664828  ADRB2; beta-2 adrenergic receptor [KO:K04142]
103664469  DRD1; D(1A) dopamine receptor [KO:K04144]
103658352  DRD5; D(1B) dopamine receptor [KO:K05840]
103669201  ADORA2A; adenosine receptor A2a [KO:K04266]
103664829  HTR4; 5-hydroxytryptamine receptor 4 [KO:K04160]
103666599  HTR6; 5-hydroxytryptamine receptor 6 [KO:K04162]
103672874  PTGER2; prostaglandin E2 receptor EP2 subtype [KO:K04259]
103658947  ADCYAP1R1; pituitary adenylate cyclase-activating polypeptide type I receptor [KO:K04587]
103660917  VIPR2; vasoactive intestinal polypeptide receptor 2 [KO:K04590]
103665890  LOW QUALITY PROTEIN: corticotropin-releasing factor receptor 1 [KO:K04578]
103658941  CRHR2; corticotropin-releasing factor receptor 2 [KO:K04579]
103671770  LHCGR; lutropin-choriogonadotropic hormone receptor [KO:K04248]
103670618  TSHR; thyrotropin receptor [KO:K04249]
103680476  MC2R; adrenocorticotropic hormone receptor [KO:K04200]
103680883  GLP1R; glucagon-like peptide 1 receptor [KO:K04581]
103657192  GIPR; gastric inhibitory polypeptide receptor isoform X1 [KO:K04580]
103672931  glucose-dependent insulinotropic receptor [KO:K08424]
103671771  FSHR; follicle-stimulating hormone receptor isoform X1 [KO:K04247]
103668723  NPR1; atrial natriuretic peptide receptor 1 isoform X1 [KO:K12323] [EC:4.6.1.2]
103670935  LOW QUALITY PROTEIN: guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas [KO:K04632]
103670936  neuroendocrine secretory protein 55 [KO:K04632]
103664910  EDN1; endothelin-1 [KO:K16366]
103670843  EDN2; endothelin-2 [KO:K16367]
103670960  endothelin-3 [KO:K05227]
103676039  SST; somatostatin [KO:K05237]
103658894  NPY; pro-neuropeptide Y [KO:K05232]
103669560  GHRL; appetite-regulating hormone isoform X3 [KO:K05254]
121104541  OXT; oxytocin-neurophysin 1 [KO:K05243]
103659720  HTR1E; 5-hydroxytryptamine receptor 1E [KO:K04153]
103675496  HTR1F; 5-hydroxytryptamine receptor 1F [KO:K04153]
103657404  HTR1B; 5-hydroxytryptamine receptor 1B [KO:K04153]
103663640  HTR1A; 5-hydroxytryptamine receptor 1A [KO:K04153]
103666567  HTR1D; 5-hydroxytryptamine receptor 1D [KO:K04153]
103678244  CHRM1; muscarinic acetylcholine receptor M1 [KO:K04129]
103669054  CHRM2; LOW QUALITY PROTEIN: muscarinic acetylcholine receptor M2 [KO:K04130]
103662377  DRD2; D(2) dopamine receptor isoform X2 [KO:K04145]
103681979  GABBR1; gamma-aminobutyric acid type B receptor subunit 1 [KO:K04615]
103678622  GABBR2; gamma-aminobutyric acid type B receptor subunit 2 [KO:K04615]
103657790  ADORA1; adenosine receptor A1 [KO:K04265]
103658004  EDNRA; endothelin-1 receptor [KO:K04197]
103658112  NPY1R; neuropeptide Y receptor type 1 [KO:K04204]
103665905  SSTR1; somatostatin receptor type 1 [KO:K04217]
103665691  SSTR2; somatostatin receptor type 2 [KO:K04218]
103668466  SSTR5; somatostatin receptor type 5 [KO:K04221]
103661147  HCAR1; hydroxycarboxylic acid receptor 1 [KO:K08401]
103661146  hydroxycarboxylic acid receptor 2 [KO:K08402]
103682504  FFAR2; free fatty acid receptor 2 [KO:K04328]
103682502  free fatty acid receptor 2-like [KO:K04328]
103677793  SUCNR1; succinate receptor 1 [KO:K10042]
103663132  PTGER3; prostaglandin E2 receptor EP3 subtype isoform X1 [KO:K04260]
121102387  OXTR; oxytocin receptor [KO:K04229]
103676206  GHSR; growth hormone secretagogue receptor type 1 [KO:K04284]
103658775  GNAI1; guanine nucleotide-binding protein G(i) subunit alpha-1 [KO:K04630]
103674803  GNAI2; guanine nucleotide-binding protein G(i) subunit alpha-2 [KO:K04630]
103675000  GNAI3; guanine nucleotide-binding protein G(i) subunit alpha-3 [KO:K04630]
103674675  ADCY1; adenylate cyclase type 1 [KO:K08041] [EC:4.6.1.1]
103679250  ADCY2; adenylate cyclase type 2 [KO:K08042] [EC:4.6.1.1]
103671685  ADCY3; adenylate cyclase type 3 [KO:K08043] [EC:4.6.1.1]
103679331  ADCY4; adenylate cyclase type 4 isoform X2 [KO:K08044] [EC:4.6.1.1]
103678826  ADCY5; adenylate cyclase type 5 [KO:K08045] [EC:4.6.1.1]
103675618  ADCY6; adenylate cyclase type 6 [KO:K08046] [EC:4.6.1.1]
103673916  ADCY7; adenylate cyclase type 7 isoform X1 [KO:K08047] [EC:4.6.1.1]
103661704  ADCY8; adenylate cyclase type 8 [KO:K08048] [EC:4.6.1.1]
103668547  ADCY9; adenylate cyclase type 9 [KO:K08049] [EC:4.6.1.1]
103667527  ADCY10; adenylate cyclase type 10 [KO:K11265] [EC:4.6.1.1]
103664172  adenylate cyclase type 10-like [KO:K11265] [EC:4.6.1.1]
103672710  CNGA1; cGMP-gated cation channel alpha-1 [KO:K04948]
103662567  CNGA2; cyclic nucleotide-gated olfactory channel [KO:K04949]
103671185  CNGA3; cyclic nucleotide-gated cation channel alpha-3 isoform X1 [KO:K04950]
103681440  CNGA4; cyclic nucleotide-gated cation channel alpha-4 [KO:K04951]
103673885  CNGB1; LOW QUALITY PROTEIN: cyclic nucleotide-gated cation channel beta-1 [KO:K04952]
103661405  CNGB3; cyclic nucleotide-gated cation channel beta-3 [KO:K04953]
103670304  CALM1; calmodulin-1 isoform X1 [KO:K02183]
103682041  CALML6; calmodulin-like protein 6 [KO:K02183]
103676238  calmodulin [KO:K02183]
103676239  CALML3; calmodulin-like protein 3 [KO:K02183]
103671240  CALM2; calmodulin-2 [KO:K02183]
103679049  CALML4; calmodulin-like protein 4 isoform X3 [KO:K02183]
103657204  CALM3; calmodulin-3 [KO:K02183]
103661761  CAMK2D; calcium/calmodulin-dependent protein kinase type II subunit delta isoform X3 [KO:K04515] [EC:2.7.11.17]
103664598  CAMK2A; calcium/calmodulin-dependent protein kinase type II subunit alpha [KO:K04515] [EC:2.7.11.17]
103668027  CAMK2G; calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X1 [KO:K04515] [EC:2.7.11.17]
103674683  CAMK2B; calcium/calmodulin-dependent protein kinase type II subunit beta isoform X1 [KO:K04515] [EC:2.7.11.17]
103675811  CAMK4; calcium/calmodulin-dependent protein kinase type IV [KO:K05869] [EC:2.7.11.17]
103675858  BVES; blood vessel epicardial substance [KO:K21108]
103678787  POPDC2; popeye domain-containing protein 2 isoform X2 [KO:K26206]
103675857  POPDC3; popeye domain-containing protein 3 [KO:K26207]
103672450  KCNK2; potassium channel subfamily K member 2 [KO:K04913]
103681759  HCN2; LOW QUALITY PROTEIN: potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 [KO:K04955]
103679133  HCN4; potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 [KO:K04957]
103657592  ABCC4; multidrug resistance-associated protein 4 [KO:K05673]
103675595  RAPGEF3; rap guanine nucleotide exchange factor 3 [KO:K08014]
103659569  RAPGEF4; rap guanine nucleotide exchange factor 4 [KO:K04351]
103657130  RRAS; ras-related protein R-Ras isoform X2 [KO:K07829]
103682372  RRAS2; LOW QUALITY PROTEIN: ras-related protein R-Ras2 [KO:K07830]
103660447  phospholipase D2 isoform X1 [KO:K01115] [EC:3.1.4.4]
103676145  PLD1; phospholipase D1 [KO:K01115] [EC:3.1.4.4]
103667971  PLCE1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 [KO:K05860] [EC:3.1.4.11]
103676947  MAPK10; mitogen-activated protein kinase 10 isoform X1 [KO:K04440] [EC:2.7.11.24]
103679990  MAPK9; mitogen-activated protein kinase 9 isoform X1 [KO:K04440] [EC:2.7.11.24]
103667893  MAPK8; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
103675043  RAP1A; ras-related protein Rap-1A isoform X1 [KO:K04353]
103659828  ras-related protein Rap-1b-like [KO:K07836]
103656863  RAP1B; ras-related protein Rap-1b [KO:K07836]
103673212  TIAM1; T-lymphoma invasion and metastasis-inducing protein 1 isoform X1 [KO:K05731]
103681714  VAV1; proto-oncogene vav isoform X1 [KO:K05730]
103675192  VAV3; guanine nucleotide exchange factor VAV3 isoform X1 [KO:K05730]
103679942  VAV2; guanine nucleotide exchange factor VAV2 [KO:K05730]
103670095  RAC1; ras-related C3 botulinum toxin substrate 1 [KO:K04392]
103676407  RAC2; ras-related C3 botulinum toxin substrate 2 isoform X1 [KO:K07860]
103666008  RAC3; ras-related C3 botulinum toxin substrate 3 isoform X1 [KO:K07861]
103678069  PAK1; serine/threonine-protein kinase PAK 1 [KO:K04409] [EC:2.7.11.1]
103663721  ARAP3; arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X1 [KO:K12490]
103674825  RHOA; transforming protein RhoA [KO:K04513]
103660799  AFDN; afadin isoform X1 [KO:K05702]
103678592  PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
103666874  PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform [KO:K00922] [EC:2.7.1.153]
103676125  PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
103675162  PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta [KO:K02649]
103663617  PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X3 [KO:K02649]
103670766  PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma [KO:K02649]
103666688  AKT3; RAC-gamma serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
103661038  AKT2; RAC-beta serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
103676878  AKT1; RAC-alpha serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
103669103  BRAF; serine/threonine-protein kinase B-raf isoform X1 [KO:K04365] [EC:2.7.11.1]
103669540  RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1 [KO:K04366] [EC:2.7.11.1]
103679064  MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 [KO:K04368] [EC:2.7.12.2]
103681834  MAP2K2; dual specificity mitogen-activated protein kinase kinase 2 [KO:K04369] [EC:2.7.12.2]
103669286  MAPK1; mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
103657827  MAPK3; mitogen-activated protein kinase 3 isoform X1 [KO:K04371] [EC:2.7.11.24]
103662972  PRKACB; cAMP-dependent protein kinase catalytic subunit beta isoform X1 [KO:K04345] [EC:2.7.11.11]
103682183  PRKACA; cAMP-dependent protein kinase catalytic subunit alpha [KO:K04345] [EC:2.7.11.11]
103661516  PPP1R1B; protein phosphatase 1 regulatory subunit 1B isoform X1 [KO:K15494]
103661277  PPP1CC; serine/threonine-protein phosphatase PP1-gamma catalytic subunit [KO:K06269] [EC:3.1.3.16]
103679611  PPP1CA; serine/threonine-protein phosphatase PP1-alpha catalytic subunit [KO:K06269] [EC:3.1.3.16]
103671909  PPP1CB; serine/threonine-protein phosphatase PP1-beta catalytic subunit [KO:K06269] [EC:3.1.3.16]
103659802  CREB1; cyclic AMP-responsive element-binding protein 1 isoform X1 [KO:K05870]
103681679  CREB3L3; cyclic AMP-responsive element-binding protein 3-like protein 3 [KO:K09048]
103668409  CREB3L4; cyclic AMP-responsive element-binding protein 3-like protein 4 isoform X1 [KO:K09048]
103667087  CREB3; cyclic AMP-responsive element-binding protein 3 [KO:K09048]
103669052  CREB3L2; cyclic AMP-responsive element-binding protein 3-like protein 2 isoform X1 [KO:K09048]
103672393  CREB3L1; cyclic AMP-responsive element-binding protein 3-like protein 1 [KO:K09048]
103658932  cyclic AMP-responsive element-binding protein 5 isoform X1 [KO:K09047]
103668810  CREB-binding protein [KO:K04498] [EC:2.3.1.48]
103674159  EP300; histone acetyltransferase p300 [KO:K04498] [EC:2.3.1.48]
103659367  BDNF; brain-derived neurotrophic factor [KO:K04355]
103671011  FOS; proto-oncogene c-Fos [KO:K04379]
103670861  JUN; transcription factor AP-1 [KO:K04448]
103674694  transcriptional activator GLI3 [KO:K06230]
103656579  GLI1; zinc finger protein GLI1 [KO:K16797]
103682234  PTCH1; LOW QUALITY PROTEIN: protein patched homolog 1 [KO:K06225]
103657987  hedgehog-interacting protein [KO:K06231]
103666055  NFKBIA; NF-kappa-B inhibitor alpha [KO:K04734]
103677947  NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1 [KO:K02580]
103679584  RELA; transcription factor p65 [KO:K04735]
121104967  LOW QUALITY PROTEIN: transcription factor SOX-9-like [KO:K18435]
103665914  LOW QUALITY PROTEIN: transcription factor SOX-9 [KO:K18435]
121102581  AMH; LOW QUALITY PROTEIN: muellerian-inhibiting factor [KO:K04665]
103674025  PPARA; peroxisome proliferator-activated receptor alpha isoform X1 [KO:K07294]
103676728  ACOX3; peroxisomal acyl-coenzyme A oxidase 3 [KO:K00232] [EC:1.3.3.6]
103665753  ACOX1; peroxisomal acyl-coenzyme A oxidase 1 isoform X1 [KO:K00232] [EC:1.3.3.6]
103658473  NFATC1; nuclear factor of activated T-cells, cytoplasmic 1 isoform X1 [KO:K04446]
103679423  BAD; bcl2-associated agonist of cell death [KO:K02158]
103680155  LIPE; hormone-sensitive lipase [KO:K07188] [EC:3.1.1.79]
103662842  ROCK1; rho-associated protein kinase 1 isoform X3 [KO:K04514] [EC:2.7.11.1]
103660117  ROCK2; rho-associated protein kinase 2 [KO:K17388] [EC:2.7.11.1]
103680852  PPP1R12A; protein phosphatase 1 regulatory subunit 12A isoform X1 [KO:K06270]
103669791  MYL9; myosin regulatory light polypeptide 9 [KO:K12755]
103663457  PLN; cardiac phospholamban [KO:K05852]
103657815  ATP2A1; sarcoplasmic/endoplasmic reticulum calcium ATPase 1 isoform X3 [KO:K05853] [EC:7.2.2.10]
103667123  ATP2A3; sarcoplasmic/endoplasmic reticulum calcium ATPase 3 isoform X1 [KO:K05853] [EC:7.2.2.10]
103661275  ATP2A2; sarcoplasmic/endoplasmic reticulum calcium ATPase 2 [KO:K05853] [EC:7.2.2.10]
103662005  RYR2; ryanodine receptor 2 [KO:K04962]
103675310  GRIN1; glutamate receptor ionotropic, NMDA 1 isoform X1 [KO:K05208]
103668590  GRIN2A; glutamate receptor ionotropic, NMDA 2A [KO:K05209]
103677769  GRIN2B; glutamate receptor ionotropic, NMDA 2B [KO:K05210]
103665926  GRIN2C; glutamate receptor ionotropic, NMDA 2C [KO:K05211]
103657232  GRIN2D; glutamate receptor ionotropic, NMDA 2D [KO:K05212]
103678631  GRIN3A; glutamate receptor ionotropic, NMDA 3A [KO:K05213]
103681771  GRIN3B; glutamate receptor ionotropic, NMDA 3B [KO:K05214]
103664566  GRIA1; glutamate receptor 1 isoform X2 [KO:K05197]
103658055  GRIA2; glutamate receptor 2 isoform X1 [KO:K05198]
103680225  GRIA3; glutamate receptor 3 isoform X1 [KO:K05199]
103662439  GRIA4; glutamate receptor 4 isoform X1 [KO:K05200]
103676590  CFTR; cystic fibrosis transmembrane conductance regulator [KO:K05031] [EC:5.6.1.6]
103669413  ATP1A1; sodium/potassium-transporting ATPase subunit alpha-1 [KO:K01539] [EC:7.2.2.13]
103672113  ATP1A2; sodium/potassium-transporting ATPase subunit alpha-2 [KO:K01539] [EC:7.2.2.13]
103680185  ATP1A3; sodium/potassium-transporting ATPase subunit alpha-3 [KO:K01539] [EC:7.2.2.13]
103672049  sodium/potassium-transporting ATPase subunit alpha-4 [KO:K01539] [EC:7.2.2.13]
103669178  ATP1B1; sodium/potassium-transporting ATPase subunit beta-1 [KO:K01540]
103678432  ATP1B3; sodium/potassium-transporting ATPase subunit beta-3 isoform X1 [KO:K01540]
103660367  ATP1B2; sodium/potassium-transporting ATPase subunit beta-2 [KO:K01540]
103680217  ATP1B4; protein ATP1B4 [KO:K01540]
103682555  FXYD1; phospholemman [KO:K13360]
103666507  SLC9A1; sodium/hydrogen exchanger 1 [KO:K05742]
103661271  ORAI1; calcium release-activated calcium channel protein 1 [KO:K16056]
103660077  ATP2B1; plasma membrane calcium-transporting ATPase 1 isoform X1 [KO:K05850] [EC:7.2.2.10]
103657738  ATP2B4; plasma membrane calcium-transporting ATPase 4 isoform X1 [KO:K05850] [EC:7.2.2.10]
103669556  ATP2B2; plasma membrane calcium-transporting ATPase 2 isoform X1 [KO:K05850] [EC:7.2.2.10]
103679703  ATP2B3; plasma membrane calcium-transporting ATPase 3 isoform X1 [KO:K05850] [EC:7.2.2.10]
103675706  CACNA1C; voltage-dependent L-type calcium channel subunit alpha-1C isoform X1 [KO:K04850]
103674739  CACNA1D; voltage-dependent L-type calcium channel subunit alpha-1D isoform X1 [KO:K04851]
103667625  CACNA1F; voltage-dependent L-type calcium channel subunit alpha-1F isoform X1 [KO:K04853]
103657769  CACNA1S; voltage-dependent L-type calcium channel subunit alpha-1S [KO:K04857]
103677806  PDE3A; cGMP-inhibited 3',5'-cyclic phosphodiesterase A [KO:K19021] [EC:3.1.4.17]
103682384  PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B [KO:K13296] [EC:3.1.4.17]
103663044  PDE4B; cAMP-specific 3',5'-cyclic phosphodiesterase 4B [KO:K13293] [EC:3.1.4.53]
103663656  PDE4D; cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X2 [KO:K13293] [EC:3.1.4.53]
103674942  PDE4C; cAMP-specific 3',5'-cyclic phosphodiesterase 4C [KO:K13293] [EC:3.1.4.53]
103678723  PDE4A; cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform X1 [KO:K13293] [EC:3.1.4.53]
103663139  cAMP-specific 3',5'-cyclic phosphodiesterase 4B-like [KO:K13293] [EC:3.1.4.53]
103660816  PDE10A; cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A isoform X1 [KO:K18438] [EC:3.1.4.17 3.1.4.35]
Compound
C00020  AMP
C00042  Succinate
C00076  Calcium cation
C00080  H+
C00165  Diacylglycerol
C00186  (S)-Lactate
C00212  Adenosine
C00238  Potassium cation
C00288  HCO3-
C00334  4-Aminobutanoate
C00416  Phosphatidate
C00547  L-Noradrenaline
C00575  3',5'-Cyclic AMP
C00584  Prostaglandin E2
C00698  Cl-
C00780  Serotonin
C00788  L-Adrenaline
C01089  (R)-3-Hydroxybutanoate
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01312  Prostaglandin I2
C01330  Sodium cation
C01996  Acetylcholine
C03758  Dopamine
C20792  Oleoylethanolamide
C20793  3-Hydroxyoctanoate
Reference
PMID:11493633
  Authors
Fimia GM, Sassone-Corsi P
  Title
Cyclic AMP signalling.
  Journal
J Cell Sci 114:1971-2 (2001)
Reference
PMID:18323530
  Authors
Serezani CH, Ballinger MN, Aronoff DM, Peters-Golden M
  Title
Cyclic AMP: master regulator of innate immune cell function.
  Journal
Am J Respir Cell Mol Biol 39:127-32 (2008)
DOI:10.1165/rcmb.2008-0091TR
Reference
PMID:24281338
  Authors
Oldenburger A, Maarsingh H, Schmidt M
  Title
Multiple facets of cAMP signalling and physiological impact: cAMP compartmentalization in the lung.
  Journal
Pharmaceuticals (Basel) 5:1291-331 (2012)
DOI:10.3390/ph5121291
Reference
PMID:24613710
  Authors
Ahuja M, Jha A, Maleth J, Park S, Muallem S
  Title
cAMP and Ca signaling in secretory epithelia: Crosstalk and synergism.
  Journal
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Related
pathway
umr00071  Fatty acid degradation
umr04015  Rap1 signaling pathway
umr04020  Calcium signaling pathway
umr04151  PI3K-Akt signaling pathway
umr04210  Apoptosis
umr04260  Cardiac muscle contraction
umr04340  Hedgehog signaling pathway
umr04720  Long-term potentiation
umr04740  Olfactory transduction
umr04972  Pancreatic secretion
umr04976  Bile secretion
KO pathway
ko04024   
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