KEGG   PATHWAY: shr04024
Entry
shr04024                    Pathway                                
Name
cAMP signaling pathway - Sarcophilus harrisii (Tasmanian devil)
Description
cAMP is one of the most common and universal second messengers, and its formation is promoted by adenylyl cyclase (AC) activation after ligation of G protein-coupled receptors (GPCRs) by ligands including hormones, neurotransmitters, and other signaling molecules. cAMP regulates pivotal physiologic processes including metabolism, secretion, calcium homeostasis, muscle contraction, cell fate, and gene transcription. cAMP acts directly on three main targets: protein kinase A (PKA), the exchange protein activated by cAMP (Epac), and cyclic nucleotide-gated ion channels (CNGCs). PKA modulates, via phosphorylation, a number of cellular substrates, including transcription factors, ion channels, transporters, exchangers, intracellular Ca2+ -handling proteins, and the contractile machinery. Epac proteins function as guanine nucleotide exchange factors (GEFs) for both Rap1 and Rap2. Various effector proteins, including adaptor proteins implicated in modulation of the actin cytoskeleton, regulators of G proteins of the Rho family, and phospholipases, relay signaling downstream from Rap.
Class
Environmental Information Processing; Signal transduction
Pathway map
shr04024  cAMP signaling pathway
shr04024

Other DBs
GO: 0019933
Organism
Sarcophilus harrisii (Tasmanian devil) [GN:shr]
Gene
105750494  VIP; VIP peptides [KO:K05264]
100915564  CRH; corticoliberin [KO:K05256]
111718575  corticoliberin-like [KO:K05256]
100915093  CGA; LOW QUALITY PROTEIN: glycoprotein hormones alpha chain [KO:K08522]
100925701  LHB; lutropin subunit beta [KO:K08521]
116419976  GPHA2; glycoprotein hormone alpha-2 [KO:K25483]
100914604  GPHB5; glycoprotein hormone beta-5 [KO:K25484]
100927019  TSHB; thyrotropin subunit beta [KO:K05251]
100925922  POMC; pro-opiomelanocortin [KO:K05228]
100934688  GCG; glucagon isoform X1 [KO:K05259]
105750388  GIP; gastric inhibitory polypeptide [KO:K05258]
100913282  FSHB; follitropin subunit beta [KO:K05250]
100928886  NPPA; natriuretic peptides A [KO:K12334]
100917392  ADCYAP1; pituitary adenylate cyclase-activating polypeptide isoform X2 [KO:K05262]
116421895  ADRB1; beta-1 adrenergic receptor [KO:K04141]
100928854  ADRB2; beta-2 adrenergic receptor [KO:K04142]
100928335  DRD1; D(1A) dopamine receptor [KO:K04144]
100920062  DRD5; D(1B) dopamine receptor [KO:K05840]
116420902  ADORA2A; adenosine receptor A2a [KO:K04266]
100931189  HTR4; 5-hydroxytryptamine receptor 4 [KO:K04160]
105750230  HTR6; 5-hydroxytryptamine receptor 6 [KO:K04162]
105749702  ADCYAP1R1; pituitary adenylate cyclase-activating polypeptide type I receptor isoform X1 [KO:K04587]
100927879  VIPR2; vasoactive intestinal polypeptide receptor 2 [KO:K04590]
100919690  CRHR1; corticotropin-releasing factor receptor 1 [KO:K04578]
100932343  corticotropin-releasing factor receptor 2 [KO:K04579]
100918852  LHCGR; lutropin-choriogonadotropic hormone receptor isoform X1 [KO:K04248]
100918071  TSHR; thyrotropin receptor [KO:K04249]
100915134  MC2R; adrenocorticotropic hormone receptor [KO:K04200]
100934009  GLP1R; glucagon-like peptide 1 receptor [KO:K04581]
100930342  GIPR; gastric inhibitory polypeptide receptor [KO:K04580]
100919982  GPR119; glucose-dependent insulinotropic receptor [KO:K08424]
100918339  FSHR; follicle-stimulating hormone receptor [KO:K04247]
100921526  NPR1; atrial natriuretic peptide receptor 1 isoform X1 [KO:K12323] [EC:4.6.1.2]
100930666  GNAS; guanine nucleotide-binding protein G(s) subunit alpha [KO:K04632]
100918955  EDN1; endothelin-1 [KO:K16366]
100933911  EDN2; endothelin-2 [KO:K16367]
100929370  EDN3; endothelin-3 [KO:K05227]
100927677  SST; somatostatin [KO:K05237]
100925985  NPY; pro-neuropeptide Y [KO:K05232]
100925855  GHRL; appetite-regulating hormone [KO:K05254]
100935082  OXT; LOW QUALITY PROTEIN: oxytocin-neurophysin 1 [KO:K05243]
100923440  HTR1B; 5-hydroxytryptamine receptor 1B [KO:K04153]
100922195  HTR1A; 5-hydroxytryptamine receptor 1A [KO:K04153]
100922896  HTR1D; 5-hydroxytryptamine receptor 1D isoform X1 [KO:K04153]
100929316  HTR1F; 5-hydroxytryptamine receptor 1F [KO:K04153]
100914839  HTR1E; 5-hydroxytryptamine receptor 1E [KO:K04153]
100919191  CHRM1; muscarinic acetylcholine receptor M1 [KO:K04129]
100925629  CHRM2; muscarinic acetylcholine receptor M2 [KO:K04130]
100915321  DRD2; D(2) dopamine receptor [KO:K04145]
100914912  GABBR1; gamma-aminobutyric acid type B receptor subunit 1 isoform X1 [KO:K04615]
100915569  GABBR2; gamma-aminobutyric acid type B receptor subunit 2 [KO:K04615]
100921347  ADORA1; adenosine receptor A1 isoform X1 [KO:K04265]
100918230  EDNRA; endothelin-1 receptor [KO:K04197]
100922666  NPY1R; neuropeptide Y receptor type 1 [KO:K04204]
100931277  SSTR1; somatostatin receptor type 1 [KO:K04217]
100925617  SSTR2; somatostatin receptor type 2 [KO:K04218]
100933805  SSTR5; somatostatin receptor type 5 isoform X1 [KO:K04221]
100930681  HCAR1; hydroxycarboxylic acid receptor 1 [KO:K08401]
100930415  HCAR2; hydroxycarboxylic acid receptor 2 [KO:K08402]
100925599  LOW QUALITY PROTEIN: free fatty acid receptor 2 [KO:K04328]
116423024  FFAR2; free fatty acid receptor 2 [KO:K04328]
100929923  SUCNR1; succinate receptor 1 [KO:K10042]
116423723  PTGER3; prostaglandin E2 receptor EP3 subtype isoform X1 [KO:K04260]
100928438  OXTR; oxytocin receptor [KO:K04229]
100927855  GHSR; growth hormone secretagogue receptor type 1 [KO:K04284]
100914706  GNAI2; guanine nucleotide-binding protein G(i) subunit alpha-2 [KO:K04630]
100928725  GNAI3; guanine nucleotide-binding protein G(i) subunit alpha [KO:K04630]
100916740  GNAI1; guanine nucleotide-binding protein G(i) subunit alpha-1 isoform X1 [KO:K04630]
100922193  ADCY1; adenylate cyclase type 1 [KO:K08041] [EC:4.6.1.1]
100922434  ADCY2; adenylate cyclase type 2 [KO:K08042] [EC:4.6.1.1]
100925657  ADCY3; adenylate cyclase type 3 [KO:K08043] [EC:4.6.1.1]
100920243  ADCY4; adenylate cyclase type 4 isoform X1 [KO:K08044] [EC:4.6.1.1]
100932634  ADCY6; adenylate cyclase type 6 isoform X1 [KO:K08046] [EC:4.6.1.1]
100929278  ADCY7; adenylate cyclase type 7 isoform X3 [KO:K08047] [EC:4.6.1.1]
100923926  ADCY8; adenylate cyclase type 8 isoform X1 [KO:K08048] [EC:4.6.1.1]
100926025  ADCY9; adenylate cyclase type 9 isoform X2 [KO:K08049] [EC:4.6.1.1]
100913418  ADCY10; adenylate cyclase type 10 isoform X1 [KO:K11265] [EC:4.6.1.1]
100932724  CNGA1; LOW QUALITY PROTEIN: cGMP-gated cation channel alpha-1 [KO:K04948]
100914161  CNGA2; cyclic nucleotide-gated olfactory channel [KO:K04949]
100917502  CNGA3; cyclic nucleotide-gated cation channel alpha-3 [KO:K04950]
100915851  CNGA4; cyclic nucleotide-gated cation channel alpha-4 [KO:K04951]
111721454  CNGB1; cyclic nucleotide-gated cation channel beta-1 [KO:K04952]
100919916  CNGB3; cyclic nucleotide-gated cation channel beta-3 [KO:K04953]
100929017  CALM1; calmodulin-1 isoform X2 [KO:K02183]
100920429  CALM2; calmodulin-2 [KO:K02183]
105750699  calmodulin-A [KO:K02183]
100935134  CALM3; calmodulin-3 isoform X1 [KO:K02183]
100925046  CALML4; calmodulin-like protein 4 [KO:K02183]
116419081  calmodulin [KO:K02183]
116423459  calmodulin-like [KO:K02183]
116423460  calmodulin-like [KO:K02183]
100934917  CAMK2A; calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1 [KO:K04515] [EC:2.7.11.17]
100916233  CAMK2G; calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X1 [KO:K04515] [EC:2.7.11.17]
100913975  CAMK2D; calcium/calmodulin-dependent protein kinase type II subunit delta isoform X1 [KO:K04515] [EC:2.7.11.17]
100918427  CAMK2B; calcium/calmodulin-dependent protein kinase type II subunit beta isoform X1 [KO:K04515] [EC:2.7.11.17]
100920792  CAMK4; calcium/calmodulin-dependent protein kinase type IV [KO:K05869] [EC:2.7.11.17]
100933664  BVES; blood vessel epicardial substance isoform X1 [KO:K21108]
100919593  POPDC2; popeye domain-containing protein 2 isoform X1 [KO:K26206]
105750465  POPDC3; popeye domain-containing protein 3 [KO:K26207]
100935232  KCNK2; potassium channel subfamily K member 2 isoform X1 [KO:K04913]
100916176  HCN2; potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 [KO:K04955]
100921984  HCN4; LOW QUALITY PROTEIN: potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 [KO:K04957]
100919152  ABCC4; multidrug resistance-associated protein 4 [KO:K05673]
100925807  RAPGEF3; rap guanine nucleotide exchange factor 3 isoform X1 [KO:K08014]
100933298  RAPGEF4; rap guanine nucleotide exchange factor 4 isoform X1 [KO:K04351]
100925964  RRAS; LOW QUALITY PROTEIN: ras-related protein R-Ras [KO:K07829]
100935072  RRAS2; ras-related protein R-Ras2 [KO:K07830]
100926651  PLD1; phospholipase D1 isoform X1 [KO:K01115] [EC:3.1.4.4]
100914579  PLD2; phospholipase D2 [KO:K01115] [EC:3.1.4.4]
100917022  LOW QUALITY PROTEIN: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 [KO:K05860] [EC:3.1.4.11]
100930815  MAPK8; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
100928480  MAPK10; mitogen-activated protein kinase 10 isoform X1 [KO:K04440] [EC:2.7.11.24]
100924267  MAPK9; mitogen-activated protein kinase 9 isoform X1 [KO:K04440] [EC:2.7.11.24]
100935403  RAP1A; ras-related protein Rap-1A isoform X2 [KO:K04353]
100920135  RAP1B; ras-related protein Rap-1b [KO:K07836]
100920711  TIAM1; T-lymphoma invasion and metastasis-inducing protein 1 isoform X1 [KO:K05731]
100919264  VAV3; guanine nucleotide exchange factor VAV3 [KO:K05730]
100933888  VAV1; proto-oncogene vav isoform X1 [KO:K05730]
100926184  VAV2; guanine nucleotide exchange factor VAV2 isoform X1 [KO:K05730]
100919657  RAC1; ras-related C3 botulinum toxin substrate 1 isoform X1 [KO:K04392]
100932383  RAC2; ras-related C3 botulinum toxin substrate 2 [KO:K07860]
100924669  RAC3; ras-related C3 botulinum toxin substrate 3 isoform X1 [KO:K07861]
100928883  PAK1; serine/threonine-protein kinase PAK 1 [KO:K04409] [EC:2.7.11.1]
100928929  ARAP3; arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X1 [KO:K12490]
100921931  RHOA; transforming protein RhoA [KO:K04513]
100934446  AFDN; afadin isoform X1 [KO:K05702]
100929811  PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
100932099  PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
105749979  PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform [KO:K00922] [EC:2.7.1.153]
100926892  PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta [KO:K02649]
100924976  PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X2 [KO:K02649]
100935230  PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1 [KO:K02649]
100917987  AKT1; RAC-alpha serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
100913262  AKT3; RAC-gamma serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
100925440  AKT2; RAC-beta serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
100934801  BRAF; serine/threonine-protein kinase B-raf isoform X1 [KO:K04365] [EC:2.7.11.1]
100935202  RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X2 [KO:K04366] [EC:2.7.11.1]
100921899  MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 isoform X1 [KO:K04368] [EC:2.7.12.2]
100917396  MAP2K2; dual specificity mitogen-activated protein kinase kinase 2 isoform X1 [KO:K04369] [EC:2.7.12.2]
100934330  MAPK3; mitogen-activated protein kinase 3 [KO:K04371] [EC:2.7.11.24]
100913231  MAPK1; mitogen-activated protein kinase 1 isoform X1 [KO:K04371] [EC:2.7.11.24]
100929360  cAMP-dependent protein kinase catalytic subunit alpha [KO:K04345] [EC:2.7.11.11]
100915481  PRKACA; cAMP-dependent protein kinase catalytic subunit alpha [KO:K04345] [EC:2.7.11.11]
100934183  PRKACB; cAMP-dependent protein kinase catalytic subunit beta isoform X2 [KO:K04345] [EC:2.7.11.11]
100913731  cAMP-dependent protein kinase catalytic subunit alpha-like [KO:K04345] [EC:2.7.11.11]
100915687  PPP1R1B; protein phosphatase 1 regulatory subunit 1B [KO:K15494]
100930570  PPP1CB; serine/threonine-protein phosphatase PP1-beta catalytic subunit [KO:K06269] [EC:3.1.3.16]
100915116  PPP1CA; serine/threonine-protein phosphatase PP1-alpha catalytic subunit [KO:K06269] [EC:3.1.3.16]
100920526  PPP1CC; serine/threonine-protein phosphatase PP1-gamma catalytic subunit isoform X1 [KO:K06269] [EC:3.1.3.16]
100913327  CREB1; cyclic AMP-responsive element-binding protein 1 isoform X1 [KO:K05870]
100926416  CREB3L2; cyclic AMP-responsive element-binding protein 3-like protein 2 [KO:K09048]
100913890  CREB3L1; cyclic AMP-responsive element-binding protein 3-like protein 1 [KO:K09048]
100916355  CREB3; cyclic AMP-responsive element-binding protein 3 [KO:K09048]
100917654  CREB3L3; cyclic AMP-responsive element-binding protein 3-like protein 3 isoform X1 [KO:K09048]
100923082  CREB3L4; cyclic AMP-responsive element-binding protein 3-like protein 4 [KO:K09048]
100922067  CREB5; cyclic AMP-responsive element-binding protein 5 isoform X1 [KO:K09047]
100921187  EP300; histone acetyltransferase p300 isoform X1 [KO:K04498] [EC:2.3.1.48]
100926283  CREBBP; CREB-binding protein isoform X2 [KO:K04498] [EC:2.3.1.48]
100934810  BDNF; brain-derived neurotrophic factor isoform X2 [KO:K04355]
100924435  FOS; proto-oncogene c-Fos [KO:K04379]
116423739  JUN; transcription factor AP-1 [KO:K04448]
100929554  GLI3; transcriptional activator GLI3 [KO:K06230]
100930638  GLI1; zinc finger protein GLI1 isoform X1 [KO:K16797]
100934585  PTCH1; protein patched homolog 1 isoform X1 [KO:K06225]
100922845  HHIP; hedgehog-interacting protein isoform X1 [KO:K06231]
100919027  NFKBIA; LOW QUALITY PROTEIN: NF-kappa-B inhibitor alpha [KO:K04734]
100917619  NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1 [KO:K02580]
100932473  RELA; transcription factor p65 [KO:K04735]
100926145  SOX9; transcription factor SOX-9 [KO:K18435]
100919390  AMH; muellerian-inhibiting factor [KO:K04665]
100917093  PPARA; peroxisome proliferator-activated receptor alpha [KO:K07294]
100926515  LOW QUALITY PROTEIN: peroxisomal acyl-coenzyme A oxidase 3-like [KO:K00232] [EC:1.3.3.6]
105750394  ACOX1; peroxisomal acyl-coenzyme A oxidase 1 isoform X1 [KO:K00232] [EC:1.3.3.6]
100926778  LOW QUALITY PROTEIN: peroxisomal acyl-coenzyme A oxidase 3-like [KO:K00232] [EC:1.3.3.6]
100926364  NFATC1; nuclear factor of activated T-cells, cytoplasmic 1 isoform X1 [KO:K04446]
100934757  F2R; proteinase-activated receptor 1 [KO:K03914]
100923199  BAD; bcl2-associated agonist of cell death isoform X1 [KO:K02158]
100926393  LIPE; hormone-sensitive lipase [KO:K07188] [EC:3.1.1.79]
100916611  ROCK1; rho-associated protein kinase 1 isoform X1 [KO:K04514] [EC:2.7.11.1]
100916865  ROCK2; rho-associated protein kinase 2 isoform X1 [KO:K17388] [EC:2.7.11.1]
100926931  PPP1R12A; protein phosphatase 1 regulatory subunit 12A isoform X1 [KO:K06270]
100917897  MYL9; myosin regulatory light polypeptide 9 [KO:K12755]
116422945  TNNI3; troponin I, cardiac muscle [KO:K12044]
100921965  PLN; cardiac phospholamban [KO:K05852]
100918964  ATP2A1; sarcoplasmic/endoplasmic reticulum calcium ATPase 1 isoform X1 [KO:K05853] [EC:7.2.2.10]
105750215  ATP2A3; sarcoplasmic/endoplasmic reticulum calcium ATPase 3 [KO:K05853] [EC:7.2.2.10]
100922099  ATP2A2; sarcoplasmic/endoplasmic reticulum calcium ATPase 2 isoform X1 [KO:K05853] [EC:7.2.2.10]
100916914  RYR2; ryanodine receptor 2 isoform X1 [KO:K04962]
100922600  GRIN1; glutamate receptor ionotropic, NMDA 1 isoform X3 [KO:K05208]
100920008  GRIN2A; glutamate receptor ionotropic, NMDA 2A isoform X1 [KO:K05209]
100926323  GRIN2B; glutamate receptor ionotropic, NMDA 2B [KO:K05210]
100922827  GRIN2C; glutamate receptor ionotropic, NMDA 2C isoform X1 [KO:K05211]
111720153  GRIN2D; LOW QUALITY PROTEIN: glutamate receptor ionotropic, NMDA 2D [KO:K05212]
100923411  GRIN3A; glutamate receptor ionotropic, NMDA 3A [KO:K05213]
100931204  GRIN3B; glutamate receptor ionotropic, NMDA 3B isoform X1 [KO:K05214]
100924175  GRIA1; glutamate receptor 1 isoform X1 [KO:K05197]
100927884  GRIA2; glutamate receptor 2 isoform X1 [KO:K05198]
100925736  GRIA3; glutamate receptor 3 isoform X2 [KO:K05199]
100929056  GRIA4; glutamate receptor 4 isoform X5 [KO:K05200]
100919086  CFTR; cystic fibrosis transmembrane conductance regulator [KO:K05031] [EC:5.6.1.6]
100922123  ATP1A3; sodium/potassium-transporting ATPase subunit alpha-3 [KO:K01539] [EC:7.2.2.13]
100928210  ATP1A1; sodium/potassium-transporting ATPase subunit alpha-1 [KO:K01539] [EC:7.2.2.13]
100914130  ATP1A2; sodium/potassium-transporting ATPase subunit alpha-2 [KO:K01539] [EC:7.2.2.13]
100918637  sodium/potassium-transporting ATPase subunit alpha-2-like isoform X2 [KO:K01539] [EC:7.2.2.13]
100935132  ATP1B3; sodium/potassium-transporting ATPase subunit beta-3 isoform X1 [KO:K01540]
100915285  ATP1B4; protein ATP1B4 [KO:K01540]
100915426  ATP1B2; sodium/potassium-transporting ATPase subunit beta-2 [KO:K01540]
100915602  ATP1B1; sodium/potassium-transporting ATPase subunit beta-1 [KO:K01540]
100929307  FXYD2; sodium/potassium-transporting ATPase subunit gamma isoform X2 [KO:K01538]
100927417  SLC9A1; sodium/hydrogen exchanger 1 [KO:K05742]
111719559  ORAI1; calcium release-activated calcium channel protein 1 [KO:K16056]
100922398  ATP2B4; plasma membrane calcium-transporting ATPase 4 isoform X3 [KO:K05850] [EC:7.2.2.10]
100921801  ATP2B1; plasma membrane calcium-transporting ATPase 1 isoform X1 [KO:K05850] [EC:7.2.2.10]
100926374  ATP2B2; plasma membrane calcium-transporting ATPase 2 isoform X1 [KO:K05850] [EC:7.2.2.10]
100930479  plasma membrane calcium-transporting ATPase 1-like [KO:K05850] [EC:7.2.2.10]
100914244  ATP2B3; plasma membrane calcium-transporting ATPase 3 isoform X3 [KO:K05850] [EC:7.2.2.10]
100926503  voltage-dependent L-type calcium channel subunit alpha-1C isoform X1 [KO:K04850]
100919750  CACNA1D; voltage-dependent L-type calcium channel subunit alpha-1D isoform X1 [KO:K04851]
100927554  CACNA1F; voltage-dependent L-type calcium channel subunit alpha-1F [KO:K04853]
100917433  CACNA1S; voltage-dependent L-type calcium channel subunit alpha-1S [KO:K04857]
100923530  PDE3A; cGMP-inhibited 3',5'-cyclic phosphodiesterase A isoform X1 [KO:K19021] [EC:3.1.4.17]
100934547  PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B isoform X1 [KO:K13296] [EC:3.1.4.17]
100931985  PDE4A; cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform X5 [KO:K13293] [EC:3.1.4.53]
100934368  PDE4B; cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1 [KO:K13293] [EC:3.1.4.53]
100915475  PDE4D; cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [KO:K13293] [EC:3.1.4.53]
100927911  PDE4C; cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X1 [KO:K13293] [EC:3.1.4.53]
100930276  PDE10A; cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A isoform X1 [KO:K18438] [EC:3.1.4.17 3.1.4.35]
Compound
C00020  AMP
C00042  Succinate
C00076  Calcium cation
C00080  H+
C00165  Diacylglycerol
C00186  (S)-Lactate
C00212  Adenosine
C00238  Potassium cation
C00288  HCO3-
C00334  4-Aminobutanoate
C00416  Phosphatidate
C00547  L-Noradrenaline
C00575  3',5'-Cyclic AMP
C00584  Prostaglandin E2
C00698  Cl-
C00780  Serotonin
C00788  L-Adrenaline
C01089  (R)-3-Hydroxybutanoate
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01312  Prostaglandin I2
C01330  Sodium cation
C01996  Acetylcholine
C03758  Dopamine
C20792  Oleoylethanolamide
C20793  3-Hydroxyoctanoate
Reference
PMID:11493633
  Authors
Fimia GM, Sassone-Corsi P
  Title
Cyclic AMP signalling.
  Journal
J Cell Sci 114:1971-2 (2001)
Reference
PMID:18323530
  Authors
Serezani CH, Ballinger MN, Aronoff DM, Peters-Golden M
  Title
Cyclic AMP: master regulator of innate immune cell function.
  Journal
Am J Respir Cell Mol Biol 39:127-32 (2008)
DOI:10.1165/rcmb.2008-0091TR
Reference
PMID:24281338
  Authors
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Related
pathway
shr00071  Fatty acid degradation
shr04015  Rap1 signaling pathway
shr04020  Calcium signaling pathway
shr04151  PI3K-Akt signaling pathway
shr04210  Apoptosis
shr04260  Cardiac muscle contraction
shr04340  Hedgehog signaling pathway
shr04720  Long-term potentiation
shr04740  Olfactory transduction
shr04972  Pancreatic secretion
shr04976  Bile secretion
KO pathway
ko04024   
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