KEGG   PATHWAY: tge04060
Entry
tge04060                    Pathway                                
Name
Cytokine-cytokine receptor interaction - Theropithecus gelada (gelada)
Description
Cytokines are soluble extracellular proteins or glycoproteins that are crucial intercellular regulators and mobilizers of cells engaged in innate as well as adaptive inflammatory host defenses, cell growth, differentiation, cell death, angiogenesis, and development and repair processes aimed at the restoration of homeostasis. Cytokines are released by various cells in the body, usually in response to an activating stimulus, and they induce responses through binding to specific receptors on the cell surface of target cells. Cytokines can be grouped by structure into different families and their receptors can likewise be grouped.
Class
Environmental Information Processing; Signaling molecules and interaction
Pathway map
tge04060  Cytokine-cytokine receptor interaction
tge04060

Organism
Theropithecus gelada (gelada) [GN:tge]
Gene
112604609  IL1RN; interleukin-1 receptor antagonist protein isoform X1 [KO:K05481]
112604621  IL1RL1; interleukin-1 receptor-like 1 isoform X1 [KO:K05171]
112604622  IL18R1; interleukin-18 receptor 1 isoform X1 [KO:K05173]
112604696  IL1B; interleukin-1 beta isoform X1 [KO:K04519]
112604767  IL1R2; interleukin-1 receptor type 2 [KO:K04387]
112604839  IL1A; interleukin-1 alpha [KO:K04383]
112604908  IL1R1; interleukin-1 receptor type 1 isoform X1 [KO:K04386]
112604921  EDAR; tumor necrosis factor receptor superfamily member EDAR isoform X1 [KO:K05162]
112604983  IL36RN; interleukin-36 receptor antagonist protein [KO:K05483]
112605002  IL36G; interleukin-36 gamma isoform X1 [KO:K05487]
112605013  IL1F10; interleukin-1 family member 10 isoform X1 [KO:K05488]
112605044  IL1RL2; interleukin-1 receptor-like 2 isoform X1 [KO:K05172]
112605075  IL18RAP; interleukin-18 receptor accessory protein [KO:K05174]
112605084  BMP10; bone morphogenetic protein 10 [KO:K22670]
112605126  GDF7; growth/differentiation factor 7 [KO:K20013]
112605137  IL37; interleukin-37 isoform X1 [KO:K05485]
112605220  IL36A; interleukin-36 alpha [KO:K05484]
112605287  IL36B; interleukin-36 beta [KO:K05486]
112605332  MPL; thrombopoietin receptor [KO:K05082]
112605466  CSF1; macrophage colony-stimulating factor 1 isoform X1 [KO:K05453]
112605580  IL18; interleukin-18 [KO:K05482]
112605656  IL20; interleukin-20 isoform X1 [KO:K22667]
112605730  IL19; interleukin-19 isoform X1 [KO:K05444]
112605784  CNTF; ciliary neurotrophic factor [KO:K05420]
112606138  IL10RA; interleukin-10 receptor subunit alpha [KO:K05134]
112606322  RELT; tumor necrosis factor receptor superfamily member 19L [KO:K05156]
112606501  CXCR5; C-X-C chemokine receptor type 5 [KO:K04190]
112606995  CLCF1; cardiotrophin-like cytokine factor 1 isoform X1 [KO:K05421]
112607640  IL11RA; interleukin-11 receptor subunit alpha isoform X1 [KO:K05056]
112607642  CCL27; C-C motif chemokine 27 [KO:K16598]
112607818  IL12RB2; interleukin-12 receptor subunit beta-2 isoform X1 [KO:K05064]
112608019  CNTFR; ciliary neurotrophic factor receptor subunit alpha [KO:K05059]
112608056  CCL19; C-C motif chemokine 19 isoform X1 [KO:K05512]
112608136  TNFSF8; tumor necrosis factor ligand superfamily member 8 isoform X1 [KO:K05471]
112608164  TGFBR1; TGF-beta receptor type-1 isoform X1 [KO:K04674] [EC:2.7.11.30]
112608178  CCL21; C-C motif chemokine 21 [KO:K16062]
112608216  [KO:K05414]
112608221  IFNA21; interferon alpha-21 [KO:K05414]
112608232  [KO:K05414]
112608255  [KO:K05414]
112608259  [KO:K05414]
112608273  [KO:K05414]
112608278  [KO:K05414]
112608298  [KO:K05414]
112608331  IFNE; interferon epsilon [KO:K05442]
112608413  IFNB1; interferon beta [KO:K05415]
112608586  IFNK; interferon kappa [KO:K05441]
112608588  IL33; interleukin-33 isoform X1 [KO:K12967]
112608614  NGF; beta-nerve growth factor [KO:K02582]
112608624  IFNW1; interferon omega-1 [KO:K05440]
112608739  TNFSF15; tumor necrosis factor ligand superfamily member 15 [KO:K05478]
112608993  TNFRSF1B; tumor necrosis factor receptor superfamily member 1B [KO:K05141]
112609001  [KO:K05150]
112609075  CCL5; C-C motif chemokine 5 [KO:K12499]
112609093  CCR10; C-C chemokine receptor type 10 [KO:K04185]
112609372  CCR7; C-C chemokine receptor type 7 isoform X1 [KO:K04182]
112609379  [KO:K05511]
112609380  CCL15; C-C motif chemokine 15 [KO:K05511]
112609381  CCL14; LOW QUALITY PROTEIN: C-C motif chemokine 14 [KO:K21092]
112609431  NGFR; tumor necrosis factor receptor superfamily member 16 isoform X1 [KO:K02583]
112609473  CXCL16; C-X-C motif chemokine 16 [KO:K10035]
112609557  TNFSF13; tumor necrosis factor ligand superfamily member 13 isoform X1 [KO:K05475]
112609558  [KO:K05474]
112609571  CCL8; C-C motif chemokine 8 isoform X1 [KO:K16596]
112609572  CCL13; C-C motif chemokine 13 [KO:K16595]
112609620  CSF3; granulocyte colony-stimulating factor isoform X1 [KO:K05423]
112609631  [KO:K12964]
112609653  TNFRSF13B; tumor necrosis factor receptor superfamily member 13B isoform X1 [KO:K05150]
112609657  [KO:K12964]
112609685  CCL18; C-C motif chemokine 18 [KO:K21094]
112609759  CCL7; C-C motif chemokine 7 isoform X1 [KO:K05509]
112609760  CCL2; C-C motif chemokine 2 [KO:K14624]
112609761  CCL11; eotaxin [KO:K16597]
112609927  [KO:K12964]
112610039  CCL1; C-C motif chemokine 1 [KO:K05514]
112610251  BMP8A; bone morphogenetic protein 8A [KO:K16622]
112610313  CCL16; C-C motif chemokine 16 [KO:K21093]
112610860  TNFSF13B; tumor necrosis factor ligand superfamily member 13B isoform X1 [KO:K05476]
112610939  TNFSF11; tumor necrosis factor ligand superfamily member 11 isoform X1 [KO:K05473]
112611001  TNFRSF19; tumor necrosis factor receptor superfamily member 19 isoform X1 [KO:K05155]
112611109  IL17D; interleukin-17D [KO:K05492]
112611536  TNFRSF11A; tumor necrosis factor receptor superfamily member 11A isoform X1 [KO:K05147]
112611562  XCL1; lymphotactin [KO:K05507]
112612052  GDF15; growth/differentiation factor 15 [KO:K05504]
112612143  CXCL17; C-X-C motif chemokine 17 [KO:K22627]
112612158  TGFB1; transforming growth factor beta-1 isoform X1 [KO:K13375]
112612265  AMH; muellerian-inhibiting factor [KO:K04665]
112612553  EBI3; interleukin-27 subunit beta [KO:K24476]
112612571  IL27RA; interleukin-27 receptor subunit alpha [KO:K19598]
112612645  EPOR; erythropoietin receptor [KO:K05079]
112612745  IL12RB1; interleukin-12 receptor subunit beta-1 isoform X1 [KO:K05063]
112612943  [KO:K22669]
112613061  CD70; CD70 antigen [KO:K05470]
112613093  [KO:K22669]
112613108  TNFSF14; tumor necrosis factor ligand superfamily member 14 isoform X1 [KO:K05477]
112613127  TNFSF9; tumor necrosis factor ligand superfamily member 9 [KO:K05472]
112613144  IFNL1; interferon lambda-1 [KO:K05447]
112613480  IL11; interleukin-11 isoform X1 [KO:K05417]
112613581  GDF1; embryonic growth/differentiation factor 1 [KO:K05495]
112613955  IL17C; interleukin-17C [KO:K05491]
112614024  TNFRSF12A; tumor necrosis factor receptor superfamily member 12A isoform X1 [KO:K05149]
112614151  [KO:K05422]
112614152  [KO:K24382]
112614212  IL34; interleukin-34 isoform X1 [KO:K22633]
112614323  CCL17; C-C motif chemokine 17 [KO:K21083]
112614329  IL21R; interleukin-21 receptor isoform X1 [KO:K05075]
112614384  CCL22; C-C motif chemokine 22 [KO:K21095]
112614423  IL4R; interleukin-4 receptor subunit alpha isoform X1 [KO:K05071]
112614466  TNFRSF17; tumor necrosis factor receptor superfamily member 17 [KO:K05153]
112614521  CX3CL1; fractalkine isoform X1 [KO:K05508]
112614578  IL27; interleukin-27 subunit alpha isoform X1 [KO:K22629]
112615453  IL2RG; cytokine receptor common subunit gamma isoform X1 [KO:K05070]
112615512  EDA; ectodysplasin-A isoform X1 [KO:K05480]
112615823  IL13RA1; interleukin-13 receptor subunit alpha-1 [KO:K05076]
112615847  CXCR3; C-X-C chemokine receptor type 3 isoform X1 [KO:K04188]
112615895  IL13RA2; interleukin-13 receptor subunit alpha-2 [KO:K05077]
112615949  CSF2RA; granulocyte-macrophage colony-stimulating factor receptor subunit alpha [KO:K05066]
112615960  CD40LG; CD40 ligand isoform X1 [KO:K03161]
112616014  IL9R; interleukin-9 receptor [KO:K05073]
112616380  CRLF2; cytokine receptor-like factor 2 [KO:K05078]
112616381  IL3RA; interleukin-3 receptor subunit alpha [KO:K04737]
112616541  BMP15; bone morphogenetic protein 15 [KO:K05498]
112616618  EDA2R; tumor necrosis factor receptor superfamily member 27 isoform X1 [KO:K05163]
112616891  [KO:K05505]
112616996  [KO:K13072]
112617116  [KO:K22687]
112617155  [KO:K22687]
112617362  [KO:K13072]
112617465  [KO:K05438]
112617528  [KO:K05438]
112617548  [KO:K22702]
112617618  TNFRSF14; tumor necrosis factor receptor superfamily member 14 [KO:K05152]
112617625  [KO:K05438]
112617626  [KO:K05438]
112617660  [KO:K05438]
112617661  [KO:K05438]
112617667  [KO:K05438]
112617688  [KO:K22669]
112617750  [KO:K05507]
112617897  [KO:K05408]
112617922  [KO:K05414]
112618147  ACKR4; atypical chemokine receptor 4 [KO:K04186]
112618287  THPO; thrombopoietin isoform X1 [KO:K06854]
112618545  TGFBR2; TGF-beta receptor type-2 isoform X1 [KO:K04388] [EC:2.7.11.30]
112618699  CCR2; C-C chemokine receptor type 2 [KO:K04177]
112618703  CCR5; C-C chemokine receptor type 5 [KO:K04180]
112618715  CX3CR1; CX3C chemokine receptor 1 [KO:K04192]
112618728  IL17RB; interleukin-17 receptor B isoform X1 [KO:K05165]
112618803  CCR1; C-C chemokine receptor type 1 [KO:K04176]
112618894  CXCR6; C-X-C chemokine receptor type 6 isoform X1 [KO:K04191]
112618898  TNFSF10; tumor necrosis factor ligand superfamily member 10 isoform X1 [KO:K04721]
112618906  ACVR2B; activin receptor type-2B [KO:K13596] [EC:2.7.11.30]
112618973  IL5RA; interleukin-5 receptor subunit alpha isoform X1 [KO:K05067]
112619043  CCR9; C-C chemokine receptor type 9 isoform X1 [KO:K04184]
112619066  IL12A; interleukin-12 subunit alpha isoform X1 [KO:K05406]
112619126  CCR3; C-C chemokine receptor type 3 isoform X1 [KO:K04178]
112619169  XCR1; chemokine XC receptor 1 [KO:K04193]
112619204  IL20RB; interleukin-20 receptor subunit beta [KO:K05137]
112619237  CCR4; C-C chemokine receptor type 4 [KO:K04179]
112619249  CCR8; C-C chemokine receptor type 8 [KO:K04183]
112619626  IL17RE; interleukin-17 receptor E [KO:K05168]
112619628  IL17RC; interleukin-17 receptor C isoform X1 [KO:K05166]
112619670  IL1RAP; interleukin-1 receptor accessory protein isoform X1 [KO:K04723]
112620311  IFNGR2; interferon gamma receptor 2 [KO:K05133]
112620495  IFNAR2; interferon alpha/beta receptor 2 isoform X1 [KO:K05131]
112620496  IL10RB; interleukin-10 receptor subunit beta [KO:K05135]
112620838  IFNAR1; interferon alpha/beta receptor 1 isoform X1 [KO:K05130]
112621058  CCL26; C-C motif chemokine 26 [KO:K21096]
112621082  LEP; leptin isoform X1 [KO:K05424]
112621270  EPO; erythropoietin isoform X1 [KO:K05437]
112621340  CCL24; C-C motif chemokine 24 [KO:K21097]
112621372  INHBA; inhibin beta A chain [KO:K04667]
112621592  IL6; interleukin-6 isoform X1 [KO:K05405]
112621817  LEPR; leptin receptor isoform X1 [KO:K05062]
112622266  PRL; prolactin [KO:K05439]
112622388  IFNGR1; interferon gamma receptor 1 isoform X1 [KO:K05132]
112622803  BMP5; bone morphogenetic protein 5 isoform X1 [KO:K04663]
112622917  TNF; tumor necrosis factor [KO:K03156]
112623174  LTA; lymphotoxin-alpha [KO:K05468]
112623282  CCR6; C-C chemokine receptor type 6 [KO:K04181]
112623300  TNFRSF21; tumor necrosis factor receptor superfamily member 21 [KO:K05157]
112623379  IL17A; interleukin-17A [KO:K05489]
112623444  BMP6; bone morphogenetic protein 6 [KO:K16620]
112623541  IL17F; interleukin-17F [KO:K05494]
112623605  LTB; lymphotoxin-beta isoform X1 [KO:K03157]
112623795  IL20RA; interleukin-20 receptor subunit alpha isoform X1 [KO:K05136]
112624237  BMPR1B; bone morphogenetic protein receptor type-1B isoform X1 [KO:K13578] [EC:2.7.11.30]
112624312  [KO:K05506]
112624313  [KO:K05506]
112624478  CXCL8; interleukin-8 [KO:K10030]
112624594  CXCL9; C-X-C motif chemokine 9 isoform X1 [KO:K05416]
112624653  [KO:K05505]
112624697  [KO:K05505]
112624754  CXCL11; C-X-C motif chemokine 11 isoform X1 [KO:K12672]
112624755  CXCL10; C-X-C motif chemokine 10 [KO:K12671]
112624776  CXCL13; C-X-C motif chemokine 13 [KO:K10032]
112624783  IL15; interleukin-15 isoform X1 [KO:K05433]
112624904  IL2; interleukin-2 [KO:K05429]
112624923  CXCL6; C-X-C motif chemokine 6 [KO:K05506]
112625021  PPBP; platelet basic protein [KO:K10029]
112625022  [KO:K05505]
112625023  BMP3; bone morphogenetic protein 3 [KO:K05496]
112625032  RELL1; RELT-like protein 1 [KO:K26541]
112625044  IL21; interleukin-21 [KO:K05434]
112625248  [KO:K05505]
112625256  PF4; platelet factor 4 isoform X1 [KO:K05407]
112625331  [KO:K05407]
112625413  TNFRSF4; tumor necrosis factor receptor superfamily member 4 [KO:K05142]
112625468  TNFRSF18; tumor necrosis factor receptor superfamily member 18 isoform X1 [KO:K05154]
112625809  IL5; interleukin-5 [KO:K05428]
112625906  IL6ST; interleukin-6 receptor subunit beta isoform X1 [KO:K05060]
112625944  CSF3R; granulocyte colony-stimulating factor receptor isoform X1 [KO:K05061]
112625968  CSF1R; macrophage colony-stimulating factor 1 receptor [KO:K05090] [EC:2.7.10.1]
112625988  [KO:K16622]
112626005  IL7R; interleukin-7 receptor subunit alpha [KO:K05072]
112626058  GHR; growth hormone receptor isoform X1 [KO:K05080]
112626411  IL12B; interleukin-12 subunit beta [KO:K05425]
112626412  IL4; interleukin-4 isoform X1 [KO:K05430]
112626443  IL13; interleukin-13 isoform X1 [KO:K05435]
112626449  CCL28; C-C motif chemokine 28 isoform X1 [KO:K05513]
112626452  TSLP; thymic stromal lymphopoietin [KO:K05436]
112626456  CSF2; granulocyte-macrophage colony-stimulating factor [KO:K05427]
112626517  LIFR; leukemia inhibitory factor receptor [KO:K05058]
112626520  RELL2; RELT-like protein 2 isoform X1 [KO:K26541]
112626557  IL17B; interleukin-17B [KO:K05490]
112626566  IL9; interleukin-9 [KO:K05432]
112626603  OSMR; oncostatin-M-specific receptor subunit beta [KO:K05057]
112626632  IL3; interleukin-3 [KO:K04736]
112626700  PRLR; prolactin receptor isoform X1 [KO:K05081]
112626795  IL6R; interleukin-6 receptor subunit alpha isoform X1 [KO:K05055]
112626948  GDF9; growth/differentiation factor 9 isoform X1 [KO:K22673]
112627004  IL31RA; LOW QUALITY PROTEIN: interleukin-31 receptor subunit alpha [KO:K22630]
112627838  IL16; pro-interleukin-16 isoform X1 [KO:K22628]
112629250  IL25; interleukin-25 isoform X1 [KO:K05493]
112629301  TGFB3; transforming growth factor beta-3 [KO:K13377]
112629358  BMP4; bone morphogenetic protein 4 isoform X1 [KO:K04662]
112629711  GDF6; growth/differentiation factor 6 [KO:K20012]
112630107  TNFRSF10A; tumor necrosis factor receptor superfamily member 10A [KO:K04722]
112630480  IL7; interleukin-7 isoform X1 [KO:K05431]
112630684  TNFRSF25; tumor necrosis factor receptor superfamily member 25 isoform X1 [KO:K05160]
112630735  TNFRSF10B; tumor necrosis factor receptor superfamily member 10B isoform X1 [KO:K04722]
112630758  TNFRSF11B; tumor necrosis factor receptor superfamily member 11B [KO:K05148]
112631178  NODAL; nodal homolog isoform X1 [KO:K04666]
112631190  IL15RA; interleukin-15 receptor subunit alpha isoform X1 [KO:K05074]
112631569  FAS; tumor necrosis factor receptor superfamily member 6 isoform X1 [KO:K04390]
112631584  CXCL12; stromal cell-derived factor 1 isoform X1 [KO:K10031]
112631620  IL2RA; interleukin-2 receptor subunit alpha isoform X1 [KO:K05068]
112631663  GDF10; growth/differentiation factor 10 isoform X1 [KO:K22674]
112631744  BMPR1A; bone morphogenetic protein receptor type-1A isoform X1 [KO:K04673] [EC:2.7.11.30]
112631982  GDF2; growth/differentiation factor 2 [KO:K05503]
112633021  IL24; interleukin-24 isoform X1 [KO:K22668]
112633025  CD40; tumor necrosis factor receptor superfamily member 5 isoform X1 [KO:K03160]
112633076  CSF2RB; cytokine receptor common subunit beta isoform X1 [KO:K04738]
112633158  LIF; leukemia inhibitory factor [KO:K05419]
112633180  BMP2; bone morphogenetic protein 2 [KO:K21283]
112633193  [KO:K05151]
112633311  GDF5; growth/differentiation factor 5 [KO:K04664]
112633333  OSM; oncostatin-M isoform X1 [KO:K05418]
112633515  IL2RB; interleukin-2 receptor subunit beta isoform X1 [KO:K05069]
112633540  IFNLR1; interferon lambda receptor 1 isoform X1 [KO:K05140]
112633620  BMP7; bone morphogenetic protein 7 isoform X1 [KO:K16621]
112633773  IL17RA; interleukin-17 receptor A isoform X1 [KO:K05164]
112634032  INHBE; inhibin beta E chain isoform X1 [KO:K22689]
112634108  CD27; CD27 antigen isoform X1 [KO:K05144]
112634139  CD4; T-cell surface glycoprotein CD4 isoform X1 [KO:K06454]
112634338  IL23A; interleukin-23 subunit alpha [KO:K05426]
112634698  IL23R; interleukin-23 receptor [KO:K05065]
112634767  IFNG; interferon gamma [KO:K04687]
112634879  IL22RA1; interleukin-22 receptor subunit alpha-1 [KO:K05138]
112634880  IL31; interleukin-31 [KO:K22631]
112634895  AMHR2; anti-Muellerian hormone type-2 receptor isoform X1 [KO:K04672] [EC:2.7.11.30]
112634913  IL22; interleukin-22 [KO:K05445]
112635063  GDF3; growth/differentiation factor 3 [KO:K22672]
112635085  ACVR1B; activin receptor type-1B isoform X1 [KO:K13567] [EC:2.7.11.30]
112635096  TNFRSF1A; tumor necrosis factor receptor superfamily member 1A isoform X1 [KO:K03158]
112635097  LTBR; tumor necrosis factor receptor superfamily member 3 isoform X1 [KO:K03159]
112635207  INHBC; inhibin beta C chain [KO:K22688]
112635364  IL26; interleukin-26 [KO:K05446]
112635457  TNFRSF8; tumor necrosis factor receptor superfamily member 8 isoform X1 [KO:K05145]
112635473  ACVRL1; serine/threonine-protein kinase receptor R3 isoform X1 [KO:K13594] [EC:2.7.11.30]
112635505  GDF11; growth/differentiation factor 11 [KO:K22679]
112635766  TNFSF18; tumor necrosis factor ligand superfamily member 18 [KO:K05479]
112635809  MSTN; growth/differentiation factor 8 [KO:K05497]
112635816  ACVR2A; activin receptor type-2A isoform X1 [KO:K04670] [EC:2.7.11.30]
112636031  BMPR2; bone morphogenetic protein receptor type-2 [KO:K04671] [EC:2.7.11.30]
112636052  TNFRSF9; tumor necrosis factor receptor superfamily member 9 [KO:K05146]
112636087  CXCR2; C-X-C chemokine receptor type 2 [KO:K05050]
112636140  IL10; interleukin-10 [KO:K05443]
112636213  CCL20; C-C motif chemokine 20 isoform X1 [KO:K14625]
112636214  ACVR1C; activin receptor type-1C isoform X1 [KO:K13568] [EC:2.7.11.30]
112636221  TNFSF4; tumor necrosis factor ligand superfamily member 4 isoform X1 [KO:K05469]
112636293  INHA; inhibin alpha chain [KO:K05500]
112636300  TGFB2; transforming growth factor beta-2 isoform X1 [KO:K13376]
112636377  CXCR4; LOW QUALITY PROTEIN: C-X-C chemokine receptor type 4 [KO:K04189]
112636566  ACVR1; activin receptor type-1 [KO:K04675] [EC:2.7.11.30]
112636637  CXCR1; C-X-C chemokine receptor type 1 isoform X1 [KO:K04175]
112636678  ACKR3; atypical chemokine receptor 3 isoform X1 [KO:K04304]
112636706  [KO:K05507]
112636918  FASLG; tumor necrosis factor ligand superfamily member 6 isoform X1 [KO:K04389]
Reference
PMID:24892271
  Authors
Turner MD, Nedjai B, Hurst T, Pennington DJ
  Title
Cytokines and chemokines: At the crossroads of cell signalling and inflammatory disease.
  Journal
Biochim Biophys Acta 1843:2563-2582 (2014)
DOI:10.1016/j.bbamcr.2014.05.014
Reference
PMID:21106488
  Authors
Brocker C, Thompson D, Matsumoto A, Nebert DW, Vasiliou V
  Title
Evolutionary divergence and functions of the human interleukin (IL) gene family.
  Journal
Hum Genomics 5:30-55 (2010)
DOI:10.1186/1479-7364-5-1-30
Reference
PMID:27577879
  Authors
Akdis M, Aab A, Altunbulakli C, Azkur K, Costa RA, Crameri R, Duan S, Eiwegger T, Eljaszewicz A, Ferstl R, Frei R, Garbani M, Globinska A, Hess L, Huitema C, Kubo T, Komlosi Z, Konieczna P, Kovacs N, Kucuksezer UC, Meyer N, Morita H, Olzhausen J, O'Mahony L, Pezer M, Prati M, Rebane A, Rhyner C, Rinaldi A, Sokolowska M, Stanic B, Sugita K, Treis A, van de Veen W, Wanke K, Wawrzyniak M, Wawrzyniak P, Wirz OF, Zakzuk JS, Akdis CA
  Title
Interleukins (from IL-1 to IL-38), interferons, transforming growth factor beta, and TNF-alpha: Receptors, functions, and roles in diseases.
  Journal
J Allergy Clin Immunol 138:984-1010 (2016)
DOI:10.1016/j.jaci.2016.06.033
Reference
PMID:15500860
  Authors
Boulanger MJ, Garcia KC
  Title
Shared cytokine signaling receptors: structural insights from the gp130 system.
  Journal
Adv Protein Chem 68:107-46 (2004)
DOI:10.1016/S0065-3233(04)68004-1
Reference
PMID:16034365
  Authors
Allan SM, Tyrrell PJ, Rothwell NJ
  Title
Interleukin-1 and neuronal injury.
  Journal
Nat Rev Immunol 5:629-40 (2005)
DOI:10.1038/nri1664
Reference
PMID:23847622
  Authors
Lopetuso LR, Chowdhry S, Pizarro TT
  Title
Opposing Functions of Classic and Novel IL-1 Family Members in Gut Health and Disease.
  Journal
Front Immunol 4:181 (2013)
DOI:10.3389/fimmu.2013.00181
Reference
PMID:21349428
  Authors
Iwakura Y, Ishigame H, Saijo S, Nakae S
  Title
Functional specialization of interleukin-17 family members.
  Journal
Immunity 34:149-62 (2011)
DOI:10.1016/j.immuni.2011.02.012
Reference
PMID:17530315
  Authors
Fischer P, Hilfiker-Kleiner D
  Title
Survival pathways in hypertrophy and heart failure: the gp130-STAT3 axis.
  Journal
Basic Res Cardiol 102:279-97 (2007)
DOI:10.1007/s00395-007-0658-z
Reference
PMID:24381786
  Authors
Richards CD
  Title
The enigmatic cytokine oncostatin m and roles in disease.
  Journal
ISRN Inflamm 2013:512103 (2013)
DOI:10.1155/2013/512103
Reference
PMID:18926762
  Authors
Zhang Q, Putheti P, Zhou Q, Liu Q, Gao W
  Title
Structures and biological functions of IL-31 and IL-31 receptors.
  Journal
Cytokine Growth Factor Rev 19:347-56 (2008)
DOI:10.1016/j.cytogfr.2008.08.003
Reference
PMID:21155715
  Authors
Meenhuis A, Verwijmeren C, Roovers O, Touw IP
  Title
The deubiquitinating enzyme DUB2A enhances CSF3 signalling by attenuating lysosomal routing of the CSF3 receptor.
  Journal
Biochem J 434:343-51 (2011)
DOI:10.1042/BJ20101628
Reference
PMID:22410872
  Authors
de Weerd NA, Nguyen T
  Title
The interferons and their receptors--distribution and regulation.
  Journal
Immunol Cell Biol 90:483-91 (2012)
DOI:10.1038/icb.2012.9
Reference
PMID:12949498
  Authors
Aggarwal BB
  Title
Signalling pathways of the TNF superfamily: a double-edged sword.
  Journal
Nat Rev Immunol 3:745-56 (2003)
DOI:10.1038/nri1184
Reference
PMID:12189384
  Authors
Ashkenazi A
  Title
Targeting death and decoy receptors of the tumour-necrosis factor superfamily.
  Journal
Nat Rev Cancer 2:420-30 (2002)
DOI:10.1038/nrc821
Reference
PMID:26115564
  Authors
Seeger P, Musso T, Sozzani S
  Title
The TGF-beta superfamily in dendritic cell biology.
  Journal
Cytokine Growth Factor Rev 26:647-57 (2015)
DOI:10.1016/j.cytogfr.2015.06.002
Reference
PMID:23612460
  Authors
Wakefield LM, Hill CS
  Title
Beyond TGFbeta: roles of other TGFbeta superfamily members in cancer.
  Journal
Nat Rev Cancer 13:328-41 (2013)
DOI:10.1038/nrc3500
Reference
PMID:22710174
  Authors
Mueller TD, Nickel J
  Title
Promiscuity and specificity in BMP receptor activation.
  Journal
FEBS Lett 586:1846-59 (2012)
DOI:10.1016/j.febslet.2012.02.043
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