KEGG   PATHWAY: oas05164
Entry
oas05164                    Pathway                                
Name
Influenza A - Ovis aries (sheep)
Description
Influenza is a contagious respiratory disease caused by influenza virus infection. Influenza A virus is responsible for both annual seasonal epidemics and periodic worldwide pandemics. Novel strains that cause pandemics arise from avian influenza virus by genetic reassortment among influenza viruses and two surface glycoproteins HA and NA form the basis of serologically distinct virus types. The innate immune system recognizes invaded virus through multiple mechanisms. Viral non-structural NS1 protein is a multifunctional virulence factor that interfere IFN-mediated antiviral response. It inhibits IFN production by blocking activation of transcription factors such as NF-kappa B and IRF3. NS1 further inhibits the activation of IFN-induced antiviral genes. PB1-F2 protein is another virulence factor that induce apoptosis of infected cells, which results in life-threatening bronchiolitis.
Class
Human Diseases; Infectious disease: viral
Pathway map
oas05164  Influenza A
oas05164

Organism
Ovis aries (sheep) [GN:oas]
Gene
100144429  tryptase-2 precursor [KO:K01340] [EC:3.4.21.59]
443433  TPSB2; tryptase beta-2 precursor [KO:K01340] [EC:3.4.21.59]
101112066  PLG; plasminogen [KO:K01315] [EC:3.4.21.7]
101112559  PRSS2; trypsin-2 isoform X1 [KO:K01312] [EC:3.4.21.4]
101111795  serine protease 1 [KO:K01312] [EC:3.4.21.4]
101112049  serine protease 1 [KO:K01312] [EC:3.4.21.4]
101120216  TMPRSS2; transmembrane protease serine 2 isoform X2 [KO:K09633] [EC:3.4.21.122]
101121197  TMPRSS4; transmembrane protease serine 4 isoform X2 [KO:K09635] [EC:3.4.21.-]
101120751  TMPRSS11D; transmembrane protease serine 11D [KO:K09641] [EC:3.4.21.-]
101118410  PRKCB; protein kinase C beta type isoform X1 [KO:K19662] [EC:2.7.11.13]
105602911  2'-5'-oligoadenylate synthase 1 [KO:K14216] [EC:2.7.7.84]
101109915  2'-5'-oligoadenylate synthase 2 isoform X1 [KO:K14216] [EC:2.7.7.84]
101112122  2'-5'-oligoadenylate synthase 3-like isoform X2 [KO:K14216] [EC:2.7.7.84]
101103495  RNASEL; 2-5A-dependent ribonuclease [KO:K01165]
101122104  DNAJB1; dnaJ homolog subfamily B member 1 [KO:K09507]
101110685  DNAJC3; dnaJ homolog subfamily C member 3 [KO:K09523]
101121673  EIF2AK2; interferon-induced, double-stranded RNA-activated protein kinase isoform X1 [KO:K16195] [EC:2.7.11.1]
101102204  eukaryotic translation initiation factor 2 subunit 1 [KO:K03237]
101113414  EIF2S1; eukaryotic translation initiation factor 2 subunit 1 [KO:K03237]
105603981  eukaryotic translation initiation factor 2 subunit 1-like [KO:K03237]
101122873  TRIM25; E3 ubiquitin/ISG15 ligase TRIM25 [KO:K10652] [EC:2.3.2.27]
101107257  RIGI; antiviral innate immune response receptor RIG-I [KO:K12646] [EC:5.6.2.6]
101106234  IFIH1; interferon-induced helicase C domain-containing protein 1 [KO:K12647] [EC:5.6.2.6]
101108417  NLRX1; NLR family member X1 isoform X1 [KO:K12653]
101119838  MAVS; mitochondrial antiviral-signaling protein isoform X1 [KO:K12648]
101111143  CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1 [KO:K04467] [EC:2.7.11.10]
780484  IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X2 [KO:K07209] [EC:2.7.11.10]
101107332  IKBKG; NF-kappa-B essential modulator isoform X3 [KO:K07210]
101113618  NFKBIB; NF-kappa-B inhibitor beta [KO:K02581]
780520  NFKBIA; NF-kappa-B inhibitor alpha [KO:K04734]
101108228  NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X2 [KO:K02580]
101102191  RELA; transcription factor p65 [KO:K04735]
101114034  CALCOCO2; calcium-binding and coiled-coil domain-containing protein 2 [KO:K21348]
554258  TLR3; toll-like receptor 3 precursor [KO:K05401]
101111016  TICAM1; TIR domain-containing adapter molecule 1 [KO:K05842]
100036758  TRAF3; TNF receptor-associated factor 3 isoform X1 [KO:K03174]
101110830  TBK1; serine/threonine-protein kinase TBK1 [KO:K05410] [EC:2.7.11.10]
101116923  IKBKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform X1 [KO:K07211] [EC:2.7.11.10]
780485  IRF3; interferon regulatory factor 3 [KO:K05411]
101110136  EP300; histone acetyltransferase p300 isoform X1 [KO:K04498] [EC:2.3.1.48]
101123600  CREBBP; CREB-binding protein [KO:K04498] [EC:2.3.1.48]
554263  TLR4; toll-like receptor 4 precursor [KO:K10160]
554254  TLR7; toll-like receptor 7 precursor [KO:K05404]
678682  MYD88; myeloid differentiation primary response protein MyD88 [KO:K04729]
100216438  IRAK4; interleukin-1 receptor-associated kinase 4 [KO:K04733] [EC:2.7.11.1]
101103683  IRF7; interferon regulatory factor 7 isoform X1 [KO:K09447]
443404  IL1A; interleukin-1 alpha precursor [KO:K04383]
443539  IL1B; interleukin-1 beta precursor [KO:K04519]
443406  IL6; interleukin-6 precursor [KO:K05405]
443064  IL12A; interleukin-12 subunit alpha precursor [KO:K05406]
443472  IL12B; interleukin-12 subunit beta precursor [KO:K05425]
443540  TNF; tumor necrosis factor [KO:K03156]
443418  CXCL8; interleukin-8 precursor [KO:K10030]
101120093  C-C motif chemokine 2 [KO:K14624]
101115553  CCL5; C-C motif chemokine 5 [KO:K12499]
442997  CXCL10; C-X-C motif chemokine 10 precursor [KO:K12671]
443045  ICAM1; intercellular adhesion molecule 1 precursor [KO:K06490]
101111435  interferon alpha-H-like [KO:K05414]
105601948  interferon alpha-H-like [KO:K05414]
492823  IFN1; interferon alpha-1 [KO:K05414]
101102963  interferon alpha-H-like [KO:K05414]
101105135  interferon alpha-H [KO:K05414]
101103872  interferon alpha-2-like [KO:K05414]
114113084  interferon alpha-14-like [KO:K05414]
114113089  interferon alpha-2-like [KO:K05414]
114113090  interferon alpha-H-like [KO:K05414]
114112827  interferon alpha-3-like [KO:K05414]
101105632  interferon alpha-H-like [KO:K05414]
121818512  interferon alpha-2-like [KO:K05414]
101103702  interferon beta-2-like [KO:K05415]
101103376  interferon beta-2-like [KO:K05415]
101103623  interferon beta-2 [KO:K05415]
114113004  interferon beta-2-like [KO:K05415]
114113016  interferon beta-2-like [KO:K05415]
114113206  interferon beta-2-like [KO:K05415]
114112819  interferon beta-2-like [KO:K05415]
114112835  interferon beta-2-like [KO:K05415]
114112840  interferon beta-2-like [KO:K05415]
114112883  interferon beta-2 [KO:K05415]
114112830  interferon beta-2-like [KO:K05415]
121818657  interferon beta-2-like [KO:K05415]
443126  IFNAR1; interferon alpha/beta receptor 1 precursor [KO:K05130]
443363  IFNAR2; interferon alpha/beta receptor 2 precursor [KO:K05131]
101110716  JAK1; tyrosine-protein kinase JAK1 [KO:K11217] [EC:2.7.10.2]
101117248  TYK2; non-receptor tyrosine-protein kinase TYK2 [KO:K11219] [EC:2.7.10.2]
100294595  SOCS3; suppressor of cytokine signaling 3 [KO:K04696]
100307049  STAT1; signal transducer and activator of transcription 1-alpha/beta [KO:K11220]
101108211  STAT2; signal transducer and activator of transcription 2 isoform X1 [KO:K11221]
101116656  IRF9; interferon regulatory factor 9 isoform X3 [KO:K04693]
443146  MX1; interferon-induced GTP-binding protein Mx1 [KO:K14754]
780441  MX2; interferon-induced GTP-binding protein Mx2 [KO:K14754]
101111580  PML; protein PML isoform X1 [KO:K10054] [EC:2.3.2.-]
443396  IFNG; interferon gamma precursor [KO:K04687]
101112907  IFNGR1; interferon gamma receptor 1 isoform X2 [KO:K05132]
101122484  IFNGR2; interferon gamma receptor 2 isoform X2 [KO:K05133]
101113909  JAK2; tyrosine-protein kinase JAK2 [KO:K04447] [EC:2.7.10.2]
101106564  CIITA; MHC class II transactivator isoform X1 [KO:K08060] [EC:2.7.11.1]
100144749  DYA; MHC class II antigen DY alpha precursor [KO:K06752]
101108696  SLA class II histocompatibility antigen, DQ haplotype D alpha chain-like [KO:K06752]
101108962  DQA; HLA class II histocompatibility antigen, DQ alpha 2 chain precursor [KO:K06752]
101119342  OVAR-DRB1; DLA class II histocompatibility antigen, DR-1 beta chain-like precursor [KO:K06752]
101109747  mamu class II histocompatibility antigen, DR alpha chain-like precursor [KO:K06752]
101108961  DLA class II histocompatibility antigen, DR-1 beta chain-like isoform X2 [KO:K06752]
101109219  HLA class II histocompatibility antigen, DO beta chain isoform X1 [KO:K06752]
101109746  HLA class II histocompatibility antigen, DM beta chain isoform X2 [KO:K06752]
101110545  HLA class II histocompatibility antigen, DO alpha chain [KO:K06752]
101116099  HLA class II histocompatibility antigen, DM alpha chain isoform X2 [KO:K06752]
101114758  LOW QUALITY PROTEIN: DLA class II histocompatibility antigen, DR-1 beta chain [KO:K06752]
101118514  boLa class II histocompatibility antigen, DQB*0101 beta chain isoform X2 [KO:K06752]
101120392  boLa class II histocompatibility antigen, DQB*0101 beta chain isoform X2 [KO:K06752]
101115073  rano class II histocompatibility antigen, A beta chain isoform X1 [KO:K06752]
101107699  NLRP3; NACHT, LRR and PYD domains-containing protein 3 isoform X1 [KO:K12800]
101105208  apoptosis-associated speck-like protein containing a CARD [KO:K12799]
101117013  CASP1; caspase-1 isoform X1 [KO:K01370] [EC:3.4.22.36]
443206  IL18; interleukin-18 [KO:K05482]
101116705  IL33; interleukin-33 isoform X1 [KO:K12967]
101123247  PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1 [KO:K02649]
101111546  PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta isoform X2 [KO:K02649]
101121455  PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X3 [KO:K02649]
101109759  PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
101110015  PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
101117348  PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X3 [KO:K00922] [EC:2.7.1.153]
101118462  AKT3; RAC-gamma serine/threonine-protein kinase isoform X2 [KO:K04456] [EC:2.7.11.1]
101119242  AKT2; RAC-beta serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
100294652  AKT1; RAC-alpha serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
100147798  CCND3; G1/S-specific cyclin-D3 [KO:K10152]
100144756  CDK4; cyclin-dependent kinase 4 [KO:K02089] [EC:2.7.11.22]
100144761  CDK6; cyclin-dependent kinase 6 isoform X1 [KO:K02091] [EC:2.7.11.22]
101114153  TNFSF10; tumor necrosis factor ligand superfamily member 10 isoform X1 [KO:K04721]
100135696  FASLG; tumor necrosis factor ligand superfamily member 6 [KO:K04389]
100144426  FAS; tumor necrosis factor receptor superfamily member 6 precursor [KO:K04390]
100135698  TNFRSF1A; tumor necrosis factor receptor superfamily member 1A precursor [KO:K03158]
101111042  TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein [KO:K03171]
101116783  FADD; FAS-associated death domain protein [KO:K02373]
101107334  CASP8; caspase-8 isoform X1 [KO:K04398] [EC:3.4.22.61]
101117837  BID; BH3-interacting domain death agonist isoform X2 [KO:K04726]
443059  BAX; apoptosis regulator BAX isoform X1 [KO:K02159]
443062  BAK1; bcl-2 homologous antagonist/killer [KO:K14021]
100145866  VDAC1; voltage-dependent anion-selective channel protein 1 [KO:K05862]
100147787  SLC25A4; ADP/ATP translocase 1 [KO:K05863]
100147789  SLC25A6; ADP/ATP translocase 3 [KO:K05863]
101122465  SLC25A31; ADP/ATP translocase 4 [KO:K05863]
100147788  SLC25A5; ADP/ATP translocase 2 [KO:K05863]
106990363  cytochrome c-like [KO:K08738]
106990092  cytochrome c [KO:K08738]
101117527  cytochrome c [KO:K08738]
114108777  cytochrome c [KO:K08738]
101104844  cytochrome c-like [KO:K08738]
101110611  cytochrome c-like [KO:K08738]
101111101  cytochrome c-like [KO:K08738]
101113375  cytochrome c-like [KO:K08738]
101118037  cytochrome c-like [KO:K08738]
101123328  cytochrome c-like [KO:K08738]
105602596  cytochrome c-like [KO:K08738]
105603035  cytochrome c-like [KO:K08738]
114113248  cytochrome c-like [KO:K08738]
114115222  cytochrome c [KO:K08738]
114115598  cytochrome c-like [KO:K08738]
114115604  cytochrome c-like [KO:K08738]
114115652  cytochrome c-like [KO:K08738]
114117847  cytochrome c-like [KO:K08738]
101107359  cytochrome c [KO:K08738]
100135699  APAF1; apoptotic protease-activating factor 1 isoform X2 [KO:K02084]
101110953  CASP9; caspase-9 isoform X2 [KO:K04399] [EC:3.4.22.62]
443031  CASP3; caspase-3 isoform X1 [KO:K02187] [EC:3.4.22.56]
105604798  CPSF4; cleavage and polyadenylation specificity factor subunit 4 isoform X4 [KO:K14404]
101108854  PABPN1L; embryonic polyadenylate-binding protein 2 [KO:K14396]
105608566  PABPN1; LOW QUALITY PROTEIN: polyadenylate-binding protein 2 [KO:K14396]
101120992  nuclear RNA export factor 2-like [KO:K14284]
101123536  nuclear RNA export factor 3-like isoform X1 [KO:K14284]
101115327  NXF1; nuclear RNA export factor 1 [KO:K14284]
101116890  LOW QUALITY PROTEIN: nuclear RNA export factor 3-like [KO:K14284]
105601901  LOW QUALITY PROTEIN: nuclear RNA export factor 3-like [KO:K14284]
101103747  NXT1; NTF2-related export protein 1 [KO:K14285]
105604278  NTF2-related export protein 2-like [KO:K14285]
101109079  NTF2-related export protein 2 [KO:K14285]
105605624  NXT2; NTF2-related export protein 2 isoform X2 [KO:K14285]
101122300  HNRNPUL1; heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform X1 [KO:K15047]
101117864  RAE1; mRNA export factor RAE1 isoform X2 [KO:K14298]
101117360  NUP98; nuclear pore complex protein Nup98-Nup96 isoform X1 [KO:K14297]
101115013  RSAD2; S-adenosylmethionine-dependent nucleotide dehydratase RSAD2 [KO:K15045]
101119093  FDPS; farnesyl pyrophosphate synthase isoform X1 [KO:K00787] [EC:2.5.1.1 2.5.1.10]
101110074  PRKCA; protein kinase C alpha type isoform X1 [KO:K02677] [EC:2.7.11.13]
101103190  RAF1; RAF proto-oncogene serine/threonine-protein kinase [KO:K04366] [EC:2.7.11.1]
101123635  MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 isoform X2 [KO:K04368] [EC:2.7.12.2]
101113846  MAP2K2; dual specificity mitogen-activated protein kinase kinase 2 isoform X1 [KO:K04369] [EC:2.7.12.2]
101115485  MAPK1; mitogen-activated protein kinase 1 isoform X2 [KO:K04371] [EC:2.7.11.24]
101123008  MAPK3; mitogen-activated protein kinase 3 [KO:K04371] [EC:2.7.11.24]
443340  ACTG1; actin, cytoplasmic 2 [KO:K05692]
443052  ACTB; actin, cytoplasmic 1 [KO:K05692]
780464  RAB11A; ras-related protein Rab-11A [KO:K07904]
101103562  RAB11B; ras-related protein Rab-11B [KO:K07905]
101118599  XPO1; exportin-1 isoform X1 [KO:K14290]
101113813  KPNA1; importin subunit alpha-5 [KO:K23940]
101106952  KPNA2; importin subunit alpha-1 [KO:K15043]
101114078  KPNA7; importin subunit alpha-8 [KO:K15043]
101104721  LOW QUALITY PROTEIN: importin subunit alpha-1-like [KO:K15043]
101104498  KPNA5; importin subunit alpha-6 [KO:K15042]
101117141  KPNA6; importin subunit alpha-7 isoform X2 [KO:K15042]
Compound
C00027  Hydrogen peroxide
C00080  H+
C05981  Phosphatidylinositol-3,4,5-trisphosphate
Reference
PMID:24225499
  Authors
Edinger TO, Pohl MO, Stertz S
  Title
Entry of influenza A virus: host factors and antiviral targets.
  Journal
J Gen Virol 95:263-77 (2014)
DOI:10.1099/vir.0.059477-0
Reference
PMID:19565019
  Authors
Kido H, Okumura Y, Takahashi E, Pan HY, Wang S, Chida J, Le TQ, Yano M
  Title
Host envelope glycoprotein processing proteases are indispensable for entry into human cells by seasonal and highly pathogenic avian influenza viruses.
  Journal
J Mol Genet Med 3:167-75 (2008)
Reference
PMID:27751627
  Authors
Ramakrishnan B, Viswanathan K, Tharakaraman K, Dancik V, Raman R, Babcock GJ, Shriver Z, Sasisekharan R
  Title
A Structural and Mathematical Modeling Analysis of the Likelihood of Antibody-Dependent Enhancement in Influenza.
  Journal
Trends Microbiol 24:933-943 (2016)
DOI:10.1016/j.tim.2016.09.003
Reference
PMID:18588994
  Authors
Thanh TT, van Doorn HR, de Jong MD
  Title
Human H5N1 influenza: current insight into pathogenesis.
  Journal
Int J Biochem Cell Biol 40:2671-4 (2008)
DOI:10.1016/j.biocel.2008.05.019
Reference
PMID:23977434
  Authors
Michael P, Brabant D, Bleiblo F, Ramana CV, Rutherford M, Khurana S, Tai TC, Kumar A, Kumar A
  Title
Influenza A induced cellular signal transduction pathways.
  Journal
J Thorac Dis 5 Suppl 2:S132-41 (2013)
DOI:10.3978/j.issn.2072-1439.2013.07.42
Reference
PMID:20020828
  Authors
Hale BG, Albrecht RA, Garcia-Sastre A
  Title
Innate immune evasion strategies of influenza viruses.
  Journal
Future Microbiol 5:23-41 (2010)
DOI:10.2217/fmb.09.108
Reference
PMID:21698289
  Authors
Sharma K, Tripathi S, Ranjan P, Kumar P, Garten R, Deyde V, Katz JM, Cox NJ, Lal RB, Sambhara S, Lal SK
  Title
Influenza A virus nucleoprotein exploits Hsp40 to inhibit PKR activation.
  Journal
PLoS One 6:e20215 (2011)
DOI:10.1371/journal.pone.0020215
Reference
PMID:19782761
  Authors
Ehrhardt C, Seyer R, Hrincius ER, Eierhoff T, Wolff T, Ludwig S
  Title
Interplay between influenza A virus and the innate immune signaling.
  Journal
Microbes Infect 12:81-7 (2010)
DOI:10.1016/j.micinf.2009.09.007
Reference
PMID:23170167
  Authors
van de Sandt CE, Kreijtz JH, Rimmelzwaan GF
  Title
Evasion of influenza A viruses from innate and adaptive immune responses.
  Journal
Viruses 4:1438-76 (2012)
DOI:10.3390/v4091438
Reference
PMID:30487536
  Authors
Long JS, Mistry B, Haslam SM, Barclay WS
  Title
Host and viral determinants of influenza A virus species specificity.
  Journal
Nat Rev Microbiol 17:67-81 (2019)
DOI:10.1038/s41579-018-0115-z
Reference
PMID:29556226
  Authors
Chen X, Liu S, Goraya MU, Maarouf M, Huang S, Chen JL
  Title
Host Immune Response to Influenza A Virus Infection.
  Journal
Front Immunol 9:320 (2018)
DOI:10.3389/fimmu.2018.00320
Reference
PMID:20130137
  Authors
Lu X, Masic A, Li Y, Shin Y, Liu Q, Zhou Y
  Title
The PI3K/Akt pathway inhibits influenza A virus-induced Bax-mediated apoptosis by negatively regulating the JNK pathway via ASK1.
  Journal
J Gen Virol 91:1439-49 (2010)
DOI:10.1099/vir.0.018465-0
Reference
PMID:18980544
  Authors
Ichinohe T, Iwasaki A, Hasegawa H
  Title
Innate sensors of influenza virus: clues to developing better intranasal vaccines.
  Journal
Expert Rev Vaccines 7:1435-45 (2008)
DOI:10.1586/14760584.7.9.1435
Reference
PMID:27231932
  Authors
Le Sage V, Cinti A, Amorim R, Mouland AJ
  Title
Adapting the Stress Response: Viral Subversion of the mTOR Signaling Pathway.
  Journal
Viruses 8:E152 (2016)
DOI:10.3390/v8060152
Reference
PMID:30510918
  Authors
Fan Y, Sanyal S, Bruzzone R
  Title
Breaking Bad: How Viruses Subvert the Cell Cycle.
  Journal
Front Cell Infect Microbiol 8:396 (2018)
DOI:10.3389/fcimb.2018.00396
Reference
PMID:21971186
  Authors
Varga ZT, Palese P
  Title
The influenza A virus protein PB1-F2: killing two birds with one stone?
  Journal
Virulence 2:542-6 (2011)
DOI:10.4161/viru.2.6.17812
Reference
PMID:30254192
  Authors
Atkin-Smith GK, Duan M, Chen W, Poon IKH
  Title
The induction and consequences of Influenza A virus-induced cell death.
  Journal
Cell Death Dis 9:1002 (2018)
DOI:10.1038/s41419-018-1035-6
Reference
PMID:30545063
  Authors
Nogales A, Martinez-Sobrido L, Topham DJ, DeDiego ML
  Title
Modulation of Innate Immune Responses by the Influenza A NS1 and PA-X Proteins.
  Journal
Viruses 10:E708 (2018)
DOI:10.3390/v10120708
Reference
PMID:21253874
  Authors
Dai X, Zhang L, Hong T
  Title
Host cellular signaling induced by influenza virus.
  Journal
Sci China Life Sci 54:68-74 (2011)
DOI:10.1007/s11427-010-4116-z
Reference
PMID:26008706
  Authors
Li J, Yu M, Zheng W, Liu W
  Title
Nucleocytoplasmic shuttling of influenza A virus proteins.
  Journal
Viruses 7:2668-82 (2015)
DOI:10.3390/v7052668
Reference
PMID:30079062
  Authors
Dou D, Revol R, Ostbye H, Wang H, Daniels R
  Title
Influenza A Virus Cell Entry, Replication, Virion Assembly and Movement.
  Journal
Front Immunol 9:1581 (2018)
DOI:10.3389/fimmu.2018.01581
Reference
PMID:23236273
  Authors
Paterson D, Fodor E
  Title
Emerging roles for the influenza A virus nuclear export protein (NEP).
  Journal
PLoS Pathog 8:e1003019 (2012)
DOI:10.1371/journal.ppat.1003019
Related
pathway
oas00900  Terpenoid backbone biosynthesis
oas03013  Nucleocytoplasmic transport
oas03015  mRNA surveillance pathway
oas04010  MAPK signaling pathway
oas04110  Cell cycle
oas04144  Endocytosis
oas04210  Apoptosis
oas04620  Toll-like receptor signaling pathway
oas04621  NOD-like receptor signaling pathway
oas04622  RIG-I-like receptor signaling pathway
oas04630  JAK-STAT signaling pathway
oas05416  Viral myocarditis
KO pathway
ko05164   
LinkDB

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