Entry |
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Name |
Regulation of actin cytoskeleton - Pan paniscus (bonobo) |
Class |
Cellular Processes; Cell motility
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Pathway map |
pps04810 | Regulation of actin cytoskeleton |
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Other DBs |
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Organism |
Pan paniscus (bonobo) [GN: pps]
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Gene |
100991389 | PDGFA; platelet-derived growth factor subunit A isoform X1 [KO:K04359] |
100984583 | PDGFB; platelet-derived growth factor subunit B isoform X1 [KO:K17386] |
103782638 | CHRM2; muscarinic acetylcholine receptor M2 isoform X2 [KO:K04130] |
100979240 | CHRM4; muscarinic acetylcholine receptor M4 isoform X2 [KO:K04132] |
100979605 | GNA12; guanine nucleotide-binding protein subunit alpha-12 isoform X1 [KO:K04346] |
100988877 | GNA13; guanine nucleotide-binding protein subunit alpha-13 isoform X1 [KO:K04639] |
100992242 | GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 [KO:K04347] |
100977283 | FGD1; FYVE, RhoGEF and PH domain-containing protein 1 isoform X1 [KO:K05720] |
100981246 | FGD3; FYVE, RhoGEF and PH domain-containing protein 3 [KO:K05722] |
100980143 | BCAR1; breast cancer anti-estrogen resistance protein 1 isoform X13 [KO:K05726] |
100980038 | SOS2; LOW QUALITY PROTEIN: son of sevenless homolog 2 [KO:K03099] |
100974851 | ARHGEF6; rho guanine nucleotide exchange factor 6 isoform X3 [KO:K05729] |
100989732 | PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1 [KO:K00922] [EC:2.7.1.153] |
100990828 | PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153] |
100990108 | PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1 [KO:K00922] [EC:2.7.1.153] |
100994315 | PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649] |
100986080 | PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1 [KO:K02649] |
100969981 | PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta [KO:K02649] |
100989733 | VAV3; guanine nucleotide exchange factor VAV3 isoform X2 [KO:K05730] |
100971161 | VAV2; guanine nucleotide exchange factor VAV2 isoform X1 [KO:K05730] |
100967869 | TIAM1; rho guanine nucleotide exchange factor TIAM1 isoform X1 [KO:K05731] |
100972918 | ARHGEF1; rho guanine nucleotide exchange factor 1 isoform X15 [KO:K12330] |
100981550 | ARHGEF12; rho guanine nucleotide exchange factor 12 isoform X1 [KO:K07532] |
100976112 | RAC1; ras-related C3 botulinum toxin substrate 1 isoform X2 [KO:K04392] |
100988790 | RAC3; ras-related C3 botulinum toxin substrate 3 isoform X1 [KO:K07861] |
100990246 | CDC42; cell division control protein 42 homolog isoform X3 [KO:K04393] |
100981749 | ARHGEF7; rho guanine nucleotide exchange factor 7 isoform X7 [KO:K13710] |
100989468 | PPP1R12A; protein phosphatase 1 regulatory subunit 12A isoform X1 [KO:K06270] |
100970244 | PPP1R12B; protein phosphatase 1 regulatory subunit 12B isoform X6 [KO:K12329] |
100967966 | PPP1R12C; protein phosphatase 1 regulatory subunit 12C isoform X1 [KO:K17457] |
100973169 | MYL2; myosin regulatory light chain 2, ventricular/cardiac muscle isoform [KO:K10351] |
100981324 | MYL7; myosin regulatory light chain 2, atrial isoform [KO:K12754] |
100976973 | LOW QUALITY PROTEIN: phosphatidylinositol 4-phosphate 5-kinase type-1 alpha-like [KO:K00889] [EC:2.7.1.68] |
100974306 | BAIAP2; brain-specific angiogenesis inhibitor 1-associated protein 2 isoform X1 [KO:K05627] |
100968966 | CYFIP1; cytoplasmic FMR1-interacting protein 1 isoform X2 [KO:K05749] |
100982761 | CYFIP2; cytoplasmic FMR1-interacting protein 2 isoform X2 [KO:K05749] |
100968230 | ARPC4; actin-related protein 2/3 complex subunit 4 isoform X3 [KO:K05755] |
100991419 | ARPC5L; actin-related protein 2/3 complex subunit 5-like protein [KO:K05754] |
100985354 | IQGAP1; ras GTPase-activating-like protein IQGAP1 isoform X1 [KO:K16848] |
100974131 | IQGAP3; ras GTPase-activating-like protein IQGAP3 isoform X1 [KO:K05767] |
100974171 | IQGAP2; ras GTPase-activating-like protein IQGAP2 isoform X2 [KO:K05767] |
100981046 | SPATA13; spermatogenesis-associated protein 13 isoform X6 [KO:K05769] |
100988721 | ARHGEF4; rho guanine nucleotide exchange factor 4 isoform X1 [KO:K05769] |
|
Compound |
C00681 | 1-Acyl-sn-glycerol 3-phosphate |
C04637 | 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate |
C05981 | Phosphatidylinositol-3,4,5-trisphosphate |
C11554 | 1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate |
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Reference |
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Authors |
Burridge K, Wennerberg K. |
Title |
Rho and Rac take center stage. |
Journal |
|
Reference |
|
Authors |
Schmitz AA, Govek EE, Bottner B, Van Aelst L. |
Title |
Rho GTPases: signaling, migration, and invasion. |
Journal |
|
Reference |
|
Authors |
Takai Y, Sasaki T, Matozaki T. |
Title |
Small GTP-binding proteins. |
Journal |
|
Reference |
|
Authors |
Pollard TD. |
Title |
The cytoskeleton, cellular motility and the reductionist agenda. |
Journal |
|
Reference |
|
Authors |
Ridley AJ, Schwartz MA, Burridge K, Firtel RA, Ginsberg MH, Borisy G, Parsons JT, Horwitz AR. |
Title |
Cell migration: integrating signals from front to back. |
Journal |
|
Reference |
|
Authors |
Sastry SK, Burridge K. |
Title |
Focal adhesions: a nexus for intracellular signaling and cytoskeletal dynamics. |
Journal |
|
Reference |
|
Authors |
Fukata M, Nakagawa M, Kuroda S, Kaibuchi K. |
Title |
Cell adhesion and Rho small GTPases. |
Journal |
J Cell Sci 112 ( Pt 24):4491-500 (1999) |
Related pathway |
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KO pathway |
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LinkDB |
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