KEGG   PATHWAY: vpd02024
Entry
vpd02024                    Pathway                                
Name
Quorum sensing - Variovorax paradoxus B4
Description
Quorum sensing (QS) is a regulatory system that allows bacteria to share information about cell density and adjust gene expression accordingly. All QS bacteria produce and release chemical signal molecules called autoinducers (AIs) that increase in concentration as a function of cell density. The most commonly studied AIs belong to one of the following three categories: acylated homoserine lactones, also referred to as AI-1, used by Gram-negative bacteria; peptide signals, used by Gram-positive bacteria; and AI-2, used by both Gram-negative and Gram-positive bacteria. QS can be divided into at least 4 steps: production of AIs by the bacterial cell; release of AIs, either actively or passively, into the surrounding environment; recognition of AIs by specific receptors; and leading to changes in gene regulation once they exceed a threshold concentration. The processes controlled by QS include virulence, competence, conjugation, antibiotic production, motility, sporulation, and biofilm formation.
Class
Cellular Processes; Cellular community - prokaryotes
Pathway map
vpd02024  Quorum sensing
vpd02024

Other DBs
GO: 0009372
Organism
Variovorax paradoxus B4 [GN:vpd]
Gene
VAPA_1c23720  hfq; RNA chaperone Hfq [KO:K03666]
VAPA_1c07230  trpE; anthranilate synthase component 1 TrpE [KO:K01657] [EC:4.1.3.27]
VAPA_1c07250  trpG; anthranilate synthase component 2 TrpG [KO:K01658] [EC:4.1.3.27]
VAPA_2c00050  solI; acyl-homoserine-lactone synthase SolI [KO:K13061] [EC:2.3.1.184]
VAPA_1c09960  aroG; phospho-2-dehydro-3-deoxyheptonate aldolase AroG [KO:K01626] [EC:2.5.1.54]
VAPA_2c01630  aroG; phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitive [KO:K01626] [EC:2.5.1.54]
VAPA_2c04090  two component transcriptional regulator, sensor histidine kinase [KO:K07645] [EC:2.7.13.3]
VAPA_2c03790  qseC; putative sensor protein QseC [KO:K07645] [EC:2.7.13.3]
VAPA_2c03800  qseB; putative transcriptional regulatory protein QseB [KO:K07666]
VAPA_2c04080  two component transcriptional regulator, winged helix family [KO:K07666]
VAPA_1c10210  putative two component transcriptional regulator, sensor histidine kinase [KO:K07711] [EC:2.7.13.3]
VAPA_1c10190  putative two component sigma-54 specific transcriptional regulator [KO:K07715]
VAPA_1c43160  putative flagellar transcriptional activator FlhD [KO:K02403]
VAPA_1c43150  flhC; flagellar transcriptional activator FlhC [KO:K02402]
VAPA_1c51800  kdpE; putative KDP operon transcriptional regulatory protein KdpE [KO:K07667]
VAPA_1c41550  putative transcriptional regulator, DeoR family [KO:K11531]
VAPA_1c03670  putative ABC transporter, substrate-binding protein [KO:K02055]
VAPA_1c13320  putative ABC transporter, substrate-binding protein [KO:K02055]
VAPA_1c51420  putative ABC transporter, sulfate-binding protein [KO:K02055]
VAPA_2c12520  potD; putative ABC transporter, spermidine/putrescine-binding protein PotD [KO:K02055]
VAPA_1c36450  putative spermidine/putrescine ABC transporter, spermidine/putrescine-binding protein [KO:K02055]
VAPA_1c48510  potD1; putative ABC transporter, spermidine/putrescine-binding protein PotD [KO:K02055]
VAPA_1c50230  potD2; putative ABC transporter, spermidine/putrescine-binding protein PotD [KO:K02055]
VAPA_1c13290  ABC transporter, permease protein [KO:K02053]
VAPA_1c03710  ABC transporter, permease protein [KO:K02053]
VAPA_1c13300  ABC transporter, permease protein [KO:K02053]
VAPA_1c50260  potI; putative putrescine transport system, permease protein PotI [KO:K02053]
VAPA_1c51400  putative sulfate ABC transporter, permease protein [KO:K02053]
VAPA_1c51430  ABC transporter, permease protein [KO:K02053]
VAPA_2c12550  potC; putative spermidine/putrescine ABC transporter, permease protein PotC [KO:K02053]
VAPA_1c36470  putative spermidine/putrescine ABC transporter, permease protein [KO:K02053]
VAPA_1c48530  potC; putative spermidine/putrescine ABC transporter, permease protein PotC [KO:K02053]
VAPA_1c03720  ABC transporter, permease protein [KO:K02054]
VAPA_1c50250  potB; putative spermidine/putrescine transport system, permease protein PotB [KO:K02054]
VAPA_2c12540  potB; putative spermidine/putrescine ABC transporter, permease protein PotB [KO:K02054]
VAPA_1c36460  putative spermidine/putrescine ABC transporter, permease protein [KO:K02054]
VAPA_1c48520  potH; putative spermidine/putrescine ABC transporter, permease protein PotH [KO:K02054]
VAPA_1c13280  putative sulfate/thiosulfate ABC transporter, ATP-binding protein [KO:K02052]
VAPA_1c03730  potA1; putative spermidine/putrescine ABC transporter, ATP-binding protein PotA [KO:K02052]
VAPA_1c51410  putative sulfate ABC transporter, ATP-binding protein [KO:K02052]
VAPA_2c12530  potA; putative spermidine/putrescine ABC transporter, ATP-binding protein PotA [KO:K02052]
VAPA_1c36440  putative spermidine/putrescine ABC transporter, ATP-binding protein [KO:K02052]
VAPA_1c48500  potA2; spermidine/putrescine ABC transporter, ATP-binding protein PotA [KO:K02052]
VAPA_1c06910  ABC transporter, substrate-binding protein [KO:K01999]
VAPA_1c00890  putative high-affinity branched-chain amino acid ABC transporter, branch-chain amino acid-binding protein [KO:K01999]
VAPA_1c02180  putative high-affinity branched-chain amino acid ABC transporter, branched-chain amino acid-binding protein [KO:K01999]
VAPA_1c19280  putative amino acid-binding protein [KO:K01999]
VAPA_1c04280  putative ABC transporter, substrate-binding protein [KO:K01999]
VAPA_1c12960  ABC transporter, branched-chain amino acid-binding protein [KO:K01999]
VAPA_1c22360  putative extracellular ligand-binding receptor [KO:K01999]
VAPA_1c08530  high-affinity branched-chain amino acid ABC transporter, branched-chain amino acid-binding protein [KO:K01999]
VAPA_1c08810  ABC transporter, substrate-binding protein [KO:K01999]
VAPA_1c16760  putative amino acid/amide ABC transporter, amino acid/amide-binding protein [KO:K01999]
VAPA_1c01460  putative branched-chain amino acid ABC transporter, branched-chain amino acid-binding protein [KO:K01999]
VAPA_1c01710  putative high-affinity branched-chain amino acid ABC transporter, branched-chain amino acid-binding protein [KO:K01999]
VAPA_1c04440  putative high-affinity branched-chain amino acid ABC transporter,branched-chain amino acid-binding protein [KO:K01999]
VAPA_1c15920  putative ABC transporter, substrate-binding protein [KO:K01999]
VAPA_1c15930  putative ABC transporter, substrate-binding protein [KO:K01999]
VAPA_1c15960  putative ABC transporter, substrate-binding protein [KO:K01999]
VAPA_1c18340  putative ABC transporter, branched-chain amino acid-binding protein [KO:K01999]
VAPA_2c00630  putative branched-chain amino acid ABC transporter, substrate-binding protein [KO:K01999]
VAPA_2c07030  putative branched-chain amino acid ABC transporter, branched-chain amino acid-binding protein [KO:K01999]
VAPA_1c28260  ABC transporter, substrate-binding protein [KO:K01999]
VAPA_1c35930  putative ABC transporter, branched-chain amino acid-binding protein [KO:K01999]
VAPA_1c51990  putative ABC transporter, substrate-binding protein [KO:K01999]
VAPA_2c12350  putative ABC transporter, branched-chain amino acid-binding protein [KO:K01999]
VAPA_1c26220  putative ABC transporter, branched-chain amino acid-binding protein [KO:K01999]
VAPA_1c26230  putative ABC transporter, branched-chain amino acid-binding protein [KO:K01999]
VAPA_1c36260  putative Leu/Ile/Val-binding protein [KO:K01999]
VAPA_1c30650  extracellular ligand-binding receptor [KO:K01999]
VAPA_2c00230  putative extracellular ligand-binding receptor [KO:K01999]
VAPA_2c10440  putative ABC transporter, branched-chain amino acid-binding protein [KO:K01999]
VAPA_2c03670  putative branched-chain amino acid ABC transporter, branched-chain amino acid-binding protein [KO:K01999]
VAPA_1c49610  putative ABC transporter, branched-chain amino acid-binding protein [KO:K01999]
VAPA_1c51170  putative ABC transporter, branched-chain amino acid-binding protein [KO:K01999]
VAPA_1c54300  putative ABC transporter, substrate-binding protein [KO:K01999]
VAPA_1c06900  ABC transporter, permease protein [KO:K01997]
VAPA_1c00880  putative high-affinity branched-chain amino acid ABC transporter, permease protein [KO:K01997]
VAPA_1c02190  putative high-affinity branched-chain amino acid ABC transporter, permease protein [KO:K01997 K01998]
VAPA_1c19300  putative high-affinity branched-chain amino acid ABC transporter, permease protein [KO:K01997]
VAPA_1c04290  putative high-affinity branched-chain amino acid ABC transporter, permease protein [KO:K01997]
VAPA_1c12950  high-affinity branched-chain amino acid ABC transporter, permease protein [KO:K01997]
VAPA_1c08540  putative high-affinity branched-chain amino acid ABC transporter, permease protein [KO:K01997]
VAPA_1c16770  amino acid/amide ABC transporter, permease protein [KO:K01997]
VAPA_1c01700  putative high-affinity branched-chain amino acid ABC transporter, permease protein [KO:K01997]
VAPA_1c04430  putative high-affinity branched-chain amino acid ABC transporter, permease protein [KO:K01997]
VAPA_1c15970  putative ABC transporter, permease protein [KO:K01997]
VAPA_1c13550  high-affinity branched-chain amino acid ABC transporter, permease protein [KO:K01997]
VAPA_1c18350  ABC transporter, permease protein [KO:K01997]
VAPA_2c00620  putative branched-chain amino acid ABC transporter, permease protein [KO:K01997]
VAPA_2c07020  putative branched-chain amino acid ABC transporter, permease protein [KO:K01997]
VAPA_1c35920  putative high-affinity branched-chain amino acid ABC transporter, permease protein [KO:K01997]
VAPA_1c51970  putative ABC transporter, permease protein [KO:K01997]
VAPA_2c12330  branched-chain amino acid ABC transporter, permease protein [KO:K01997]
VAPA_1c26240  ABC transporter, permease protein [KO:K01997]
VAPA_1c30610  putative ABC transporter, permease protein [KO:K01997]
VAPA_2c10410  putative branched-chain amino acid ABC transporter, permease protein [KO:K01997]
VAPA_1c51220  putative branched-chain amino acid ABC transporter, permease protein [KO:K01997]
VAPA_2c03660  putative branched-chain amino acid ABC transporter, permease protein [KO:K01997]
VAPA_1c12940  high-affinity branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01995 K01998]
VAPA_1c15980  ABC transporter, ATP-binding protein [KO:K01995 K01998]
VAPA_2c07010  putative branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01995 K01998]
VAPA_1c06890  ABC transporter, permease protein [KO:K01998]
VAPA_1c08550  putative high-affinity branched-chain amino acid ABC transporter, permease protein [KO:K01998]
VAPA_1c16780  amino acid/amide ABC transporter, permease protein [KO:K01998]
VAPA_1c00870  putative high-affinity branched-chain amino acid ABC transporter, permease protein [KO:K01998]
VAPA_1c01690  putative high-affinity branched-chain amino acid ABC transporter, permease protein [KO:K01998]
VAPA_1c18360  ABC transporter, permease protein [KO:K01998]
VAPA_1c19290  putative high-affinity branched-chain amino acid ABC transporter, permease protein [KO:K01998]
VAPA_1c04300  putative high-affinity branched-chain amino acid ABC transporter, permease protein [KO:K01998]
VAPA_1c04420  putative high-affinity branched-chain amino acid ABC transporter, permease protein [KO:K01998]
VAPA_1c13560  high-affinity branched-chain amino acid ABC transporter, permease protein [KO:K01998]
VAPA_2c00610  putative branched-chain amino acid ABC transporter, permease protein [KO:K01998]
VAPA_2c10400  putative branched-chain amino acid ABC transporter, permease protein [KO:K01998]
VAPA_1c26250  putative branched-chain amino acid ABC transporter, permease protein [KO:K01998]
VAPA_1c51210  putative branched-chain amino acid ABC transporter, permease protein [KO:K01998]
VAPA_2c03650  putative branched-chain amino acid ABC transporter, permease protein [KO:K01998]
VAPA_2c12320  branched-chain amino acid ABC transporter, permease protein [KO:K01998]
VAPA_1c35910  putative high-affinity branched-chain amino acid ABC transporter, permease protein [KO:K01998]
VAPA_1c51980  putative ABC transporter, permease protein [KO:K01998]
VAPA_1c30600  putative ABC transporter, permease protein [KO:K01998]
VAPA_1c06880  ABC transporter, ATP-binding protein [KO:K01995]
VAPA_1c00860  putative high-affinity branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01995]
VAPA_1c02200  putative high-affinity branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01995]
VAPA_1c19310  putative high-affinity branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01995]
VAPA_1c08560  high-affinity branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01995]
VAPA_1c16790  amino acid/amide ABC transporter, ATP-binding protein [KO:K01995]
VAPA_1c01680  putative high-affinity branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01995]
VAPA_1c04310  high-affinity branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01995]
VAPA_1c04410  putative high-affinity branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01995]
VAPA_1c13570  high-affinity branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01995]
VAPA_1c18370  putative branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01995]
VAPA_2c00600  putative branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01995]
VAPA_1c35950  high-affinity branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01995]
VAPA_1c51960  ABC transporter, ATP-binding protein [KO:K01995]
VAPA_2c12310  branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01995]
VAPA_1c26260  putative branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01995]
VAPA_1c30630  putative ABC transporter, ATP-binding protein [KO:K01995]
VAPA_2c10430  putative branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01995]
VAPA_1c51200  putative branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01995]
VAPA_2c03640  putative branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01995]
VAPA_1c06870  ABC transporter, ATP-binding protein [KO:K01996]
VAPA_1c15990  ABC transporter, ATP-binding protein [KO:K01996]
VAPA_1c08570  high-affinity branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01996]
VAPA_1c16800  amino acid/amide ABC transporter, ATP-binding protein [KO:K01996]
VAPA_1c00850  putative high-affinity branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01996]
VAPA_1c01670  putative high-affinity branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01996]
VAPA_1c02210  putative high-affinity branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01996]
VAPA_1c18380  putative branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01996]
VAPA_1c19270  livF; putative high-affinity branched-chain amino acid ABC transporter, ATP-binding protein LivF [KO:K01996]
VAPA_1c04320  high-affinity branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01996]
VAPA_1c04400  putative high-affinity branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01996]
VAPA_1c12930  high-affinity branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01996]
VAPA_1c13580  high-affinity branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01996]
VAPA_2c00590  putative branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01996]
VAPA_2c10420  putative branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01996]
VAPA_1c26280  putative branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01996]
VAPA_1c51190  putative branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01996]
VAPA_2c03630  putative branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01996]
VAPA_2c12300  branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01996]
VAPA_1c35940  high-affinity branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01996]
VAPA_1c52000  putative ABC transporter, ATP-binding protein [KO:K01996]
VAPA_2c07000  ABC transporter, ATP-binding protein [KO:K01996]
VAPA_1c30620  putative ABC transporter, ATP-binding protein [KO:K01996]
VAPA_1c23220  putative transcriptional activator SRCAP-like protein [KO:K20276]
VAPA_1c47100  putative outer membrane adhesin-like protein [KO:K20276]
VAPA_1c19260  putative long-chain-fatty-acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
VAPA_1c04710  fadD; long-chain-fatty-acid--CoA ligase FadD [KO:K01897] [EC:6.2.1.3]
VAPA_1c51950  putative acyl-CoA ligase [KO:K01897] [EC:6.2.1.3]
VAPA_1c49590  putative ligase [KO:K01897] [EC:6.2.1.3]
VAPA_1c51180  putative acyl-CoA ligase [KO:K01897] [EC:6.2.1.3]
VAPA_2c03700  putative long-chain-fatty-acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
VAPA_1c13890  putative acyl-CoA ligase [KO:K01897] [EC:6.2.1.3]
VAPA_1c49250  acyl-CoA ligase [KO:K01897] [EC:6.2.1.3]
VAPA_1c50670  putative acyl-CoA ligase [KO:K01897] [EC:6.2.1.3]
VAPA_2c03570  putative acyl-CoA ligase [KO:K01897] [EC:6.2.1.3]
VAPA_2c05040  transcriptional regulator, Crp/Fnr family [KO:K10914]
VAPA_1c43600  transcriptional regulator, Crp/Fnr family [KO:K10914]
VAPA_1c32020  transcriptional regulator, Crp/Fnr family [KO:K10914]
VAPA_1c48090  putative transcriptional regulator, Crp/Fnr family [KO:K10914]
VAPA_1c13510  transcriptional regulator, Crp/Fnr family [KO:K10914]
VAPA_1c29220  putative transcriptional regulator, Crp/Fnr family [KO:K10914]
VAPA_1c00820  putative transcriptional regulator, Crp/Fnr family [KO:K10914]
VAPA_1c22160  transcriptional regulator, Crp family [KO:K10914]
VAPA_1c55080  cyclic nucleotide-binding domain-containing protein [KO:K10914]
VAPA_1c51940  transcriptional regulator, Crp/Fnr family [KO:K10914]
VAPA_1c45890  putative transcriptional regulator, Crp/Fnr family [KO:K10914]
VAPA_1c22930  transcriptional regulator, IclR family [KO:K20329]
VAPA_1c33130  transcriptional regulator, IclR family [KO:K20329]
VAPA_1c31760  ribD; riboflavin biosynthesis protein RibD [KO:K11752] [EC:3.5.4.26 1.1.1.193]
VAPA_1c50030  oprM; outer membrane protein OprM [KO:K18139]
VAPA_2c03950  oprM; putative outer membrane protein OprM [KO:K18139]
VAPA_1c14210  putative peptide ABC transporter, peptide-binding protein [KO:K02035]
VAPA_1c16510  putative peptide ABC transporter, peptide-binding protein [KO:K02035]
VAPA_1c12740  putative ABC transporter, substrate-binding protein [KO:K02035]
VAPA_1c11450  putative ABC transporter, oligopeptide/dipeptide-binding protein, family 5 [KO:K02035]
VAPA_1c37160  putative peptide ABC transporter, peptide-binding protein [KO:K02035]
VAPA_1c45240  putative peptide ABC transporter, peptide-binding protein [KO:K02035]
VAPA_1c45250  putative peptide ABC transporter, peptide-binding protein [KO:K02035]
VAPA_2c06180  putative oligopeptide/dipeptide ABC transporter, oligopeptide/dipeptide-binding protein [KO:K02035]
VAPA_1c54450  putative ABC transporter, glutathione-binding protein [KO:K02035]
VAPA_2c02610  gsiB; glutathione transport system, substrate binding protein GsiB [KO:K02035]
VAPA_1c39630  putative peptide ABC transporter, periplasmic ligand binding protein [KO:K02035]
VAPA_1c09160  ABC transporter, oligopeptid/dipeptide-binding protein [KO:K02035]
VAPA_1c09150  oligopeptide/dipeptide ABC transporter, permease protein [KO:K02033]
VAPA_1c14220  putative peptide ABC transporter, permease protein [KO:K02033]
VAPA_1c16500  putative peptide ABC transporter, permease protein [KO:K02033]
VAPA_1c12750  putative peptide ABC transporter, permease protein [KO:K02033]
VAPA_1c11430  putative oligiopeptide/dipeptide ABC transporter, permease protein [KO:K02033]
VAPA_1c37150  putative peptide ABC transporter, permease protein [KO:K02033]
VAPA_1c45200  putative peptide ABC transporter, permease protein [KO:K02033]
VAPA_2c06160  oligopeptide/dipeptide ABC transporter, permease protein [KO:K02033]
VAPA_1c54440  putative glutathione ABC transporter, permease protein [KO:K02033]
VAPA_2c02600  gsiC; glutathione transport system, permease protein GsiC [KO:K02033]
VAPA_1c39640  putative peptide ABC transporter, permease protein [KO:K02033]
VAPA_1c09140  oligopeptide/dipeptide ABC transporter, permease protein [KO:K02034]
VAPA_1c14230  putative peptide ABC transporter, permease protein [KO:K02034]
VAPA_1c16490  putative peptide ABC transporter, permease protein [KO:K02034]
VAPA_1c12760  putative peptide ABC transporter, permease protein [KO:K02034]
VAPA_1c11460  putative oligopeptide/dipeptide ABC transporter, permease protein [KO:K02034]
VAPA_1c37140  putative peptide ABC transporter, permease protein [KO:K02034]
VAPA_2c06150  putative oligopeptide/dipeptide ABC transporter, permease protein [KO:K02034]
VAPA_1c45210  ABC transporter, permease protein [KO:K02034]
VAPA_1c54430  putative glutathione ABC transporter, permease protein [KO:K02034]
VAPA_1c39650  putative peptide ABC transporter, permease protein [KO:K02034]
VAPA_2c02590  gsiD; glutathione transport system, permease protein GsiD [KO:K02034]
VAPA_1c09120  oligopeptide/dipeptide ABC transporter, ATP-binding protein [KO:K02031]
VAPA_1c16480  putative oligopeptide/dipeptide ABC transporter, ATP-binding protein [KO:K02031]
VAPA_1c12770  peptide ABC transporter, ATP-binding protein [KO:K02031]
VAPA_1c11470  oligopeptide/dipeptide ABC transporter, ATP-binding protein [KO:K02031]
VAPA_1c37130  gsiA1; putative glutathione ABC transporter, ATP-binding protein GsiA [KO:K02031 K02032]
VAPA_1c54420  gsiA2; glutathione ABC transporter, ATP-binding protein GsiA [KO:K02031 K02032]
VAPA_2c02580  gsiA; glutathione transport system, ATP-binding protein GsiA [KO:K02031 K02032]
VAPA_1c14240  putative peptide ABC transporter, ATP-binding protein [KO:K02031 K02032]
VAPA_2c06140  oligopeptide/dipeptide ABC transporter, ATP-binding protein [KO:K02031]
VAPA_1c39660  putative peptide ABC transporter, ATP-binding protein [KO:K02031]
VAPA_1c45220  putative oligopeptide/dipeptide ABC transporter, ATP-binding protein [KO:K02031]
VAPA_1c11480  oligopeptide/dipeptide ABC transporter, ATP-binding protein [KO:K02032]
VAPA_1c16470  putative oligopeptide/dipeptide ABC transporter, ATP-binding protein [KO:K02032]
VAPA_1c09130  oligopeptide/dipeptide ABC transporter, ATP-binding protein [KO:K02032]
VAPA_1c12780  peptide ABC transporter, ATP-binding protein [KO:K02032]
VAPA_1c45230  putative oligopeptide/dipeptide ABC transporter, ATP-binding protein [KO:K02032]
VAPA_1c55100  yidC; membrane protein insertase YidC [KO:K03217]
VAPA_2c01000  putative secreted peptidase [KO:K14645] [EC:3.4.21.-]
VAPA_1c07360  preprotein translocase, SecE subunit [KO:K03073]
VAPA_1c36200  secG; preprotein translocase, subunit SecG [KO:K03075]
VAPA_1c52420  secY; preprotein translocase subunit SecY [KO:K03076]
VAPA_1c53110  preprotein translocase subunit YajC [KO:K03210]
VAPA_1c43900  secA; protein translocase, subunit SecA [KO:K03070] [EC:7.4.2.8]
VAPA_1c45470  ftsY; cell division protein FtsY [KO:K03110]
VAPA_1c42550  secB; protein-export protein SecB [KO:K03071]
VAPA_1c10140  ffh; signal recognition particle protein Ffh [KO:K03106] [EC:3.6.5.4]
VAPA_1c11210  phospholipase C, phosphocholine-specific [KO:K01114] [EC:3.1.4.3]
VAPA_1c11220  phospholipase C, phosphocholine-specific [KO:K01114] [EC:3.1.4.3]
VAPA_1c09440  non-hemolytic phospholipase C [KO:K01114] [EC:3.1.4.3]
VAPA_1c32160  non-hemolytic phospholipase C [KO:K01114] [EC:3.1.4.3]
Compound
C00007  Oxygen
C00009  Orthophosphate
C00059  Sulfate
C00232  Succinate semialdehyde
C00334  4-Aminobutanoate
C00547  L-Noradrenaline
C00788  L-Adrenaline
C01019  L-Fucose
C11837  N-Butyryl-L-homoserine lactone
C11841  N-(3-Oxooctanoyl)homoserine lactone
C11844  N-Heptanoylhomoserine lactone
C11845  N-(3-Hydroxy-7-cis-tetradecenoyl)homoserine lactone
C11848  2-Heptyl-3-hydroxy-quinolone
C16421  AI-2
C16463  3',5'-Cyclic diGMP
C16640  CAI-1
C18049  N-Acyl-L-homoserine lactone
C18206  cis-11-Methyl-2-dodecenoic acid
C20643  2-Heptyl-4(1H)-quinolone
C20677  N-(4-Coumaroyl)-L-homoserine lactone
C20959  (4S)-4-Hydroxy-5-phosphooxypentane-2,3-dione
C21195  N-(3-Hydroxybutanoyl)-L-homoserine lactone
C21197  N-Hexanoyl-L-homoserine lactone
C21198  N-(3-Oxohexanoyl)-L-homoserine lactone
C21199  N-Octanoyl-L-homoserine lactone
C21200  N-3-Hydroxyoctanoyl-L-homoserine lactone
C21201  N-3-Oxo-dodecanoyl-L-homoserine lactone
C21202  cis-2-Dodecenoic acid
C21220  AIP-1
C21221  CSP
C21222  CSP
C21223  Blp
C21224  SHP2
C21225  SHP3
C21226  cCF10
C21227  iCF10
C21228  cAD1
C21229  iAD1
C21230  ComX pheromone
C21231  PhrA pentapeptide
C21232  PhrC pentapeptide
C21233  PhrE pentapeptide
C21234  PhrF pentapeptide
C21235  PhrG pentapeptide
C21236  PhrH pentapeptide
C21237  PhrK pentapeptide
C21238  NprX peptide
C21239  PapR peptide
C21241  AIP-2
C21242  AIP-3
C21243  AIP-4
C21244  AgrD peptide
C21245  AgrD1 peptide
C21246  GBAP
C21382  R-THMF
Reference
  Authors
Pereira CS, Thompson JA, Xavier KB
  Title
AI-2-mediated signalling in bacteria.
  Journal
FEMS Microbiol Rev 37:156-81 (2013)
DOI:10.1111/j.1574-6976.2012.00345.x
Reference
  Authors
Verma SC, Miyashiro T
  Title
Quorum sensing in the squid-Vibrio symbiosis.
  Journal
Int J Mol Sci 14:16386-401 (2013)
DOI:10.3390/ijms140816386
Reference
  Authors
Norsworthy AN, Visick KL
  Title
Gimme shelter: how Vibrio fischeri successfully navigates an animal's multiple environments.
  Journal
Front Microbiol 4:356 (2013)
DOI:10.3389/fmicb.2013.00356
Reference
  Authors
Papaioannou E, Utari PD, Quax WJ
  Title
Choosing an appropriate infection model to study quorum sensing inhibition in Pseudomonas infections.
  Journal
Int J Mol Sci 14:19309-40 (2013)
DOI:10.3390/ijms140919309
Reference
  Authors
Heeb S, Fletcher MP, Chhabra SR, Diggle SP, Williams P, Camara M
  Title
Quinolones: from antibiotics to autoinducers.
  Journal
FEMS Microbiol Rev 35:247-74 (2011)
DOI:10.1111/j.1574-6976.2010.00247.x
Reference
  Authors
Rasamiravaka T, Labtani Q, Duez P, El Jaziri M
  Title
The formation of biofilms by Pseudomonas aeruginosa: a review of the natural and synthetic compounds interfering with control mechanisms.
  Journal
Biomed Res Int 2015:759348 (2015)
DOI:10.1155/2015/759348
Reference
  Authors
Whiteley M, Greenberg EP
  Title
Promoter specificity elements in Pseudomonas aeruginosa quorum-sensing-controlled genes.
  Journal
J Bacteriol 183:5529-34 (2001)
DOI:10.1128/JB.183.19.5529-5534.2001
Reference
  Authors
Chin-A-Woeng TF, van den Broek D, de Voer G, van der Drift KM, Tuinman S, Thomas-Oates JE, Lugtenberg BJ, Bloemberg GV
  Title
Phenazine-1-carboxamide production in the biocontrol strain Pseudomonas chlororaphis PCL1391 is regulated by multiple factors secreted into the growth medium.
  Journal
Mol Plant Microbe Interact 14:969-79 (2001)
DOI:10.1094/MPMI.2001.14.8.969
Reference
  Authors
Hughes DT, Clarke MB, Yamamoto K, Rasko DA, Sperandio V
  Title
The QseC adrenergic signaling cascade in Enterohemorrhagic E. coli (EHEC).
  Journal
PLoS Pathog 5:e1000553 (2009)
DOI:10.1371/journal.ppat.1000553
Reference
  Authors
Njoroge J, Sperandio V
  Title
Enterohemorrhagic Escherichia coli virulence regulation by two bacterial adrenergic kinases, QseC and QseE.
  Journal
Infect Immun 80:688-703 (2012)
DOI:10.1128/IAI.05921-11
Reference
  Authors
Pacheco AR, Curtis MM, Ritchie JM, Munera D, Waldor MK, Moreira CG, Sperandio V
  Title
Fucose sensing regulates bacterial intestinal colonization.
  Journal
Nature 492:113-7 (2012)
DOI:10.1038/nature11623
Reference
  Authors
Hirakawa H, Harwood CS, Pechter KB, Schaefer AL, Greenberg EP
  Title
Antisense RNA that affects Rhodopseudomonas palustris quorum-sensing signal receptor expression.
  Journal
Proc Natl Acad Sci U S A 109:12141-6 (2012)
DOI:10.1073/pnas.1200243109
Reference
  Authors
Danino VE, Wilkinson A, Edwards A, Downie JA
  Title
Recipient-induced transfer of the symbiotic plasmid pRL1JI in Rhizobium leguminosarum bv. viciae is regulated by a quorum-sensing relay.
  Journal
Mol Microbiol 50:511-25 (2003)
DOI:10.1046/j.1365-2958.2003.03699.x
Reference
  Authors
Wisniewski-Dye F, Downie JA
  Title
Quorum-sensing in Rhizobium.
  Journal
Antonie Van Leeuwenhoek 81:397-407 (2002)
DOI:10.1023/A:1020501104051
Reference
  Authors
Rodelas B, Lithgow JK, Wisniewski-Dye F, Hardman A, Wilkinson A, Economou A, Williams P, Downie JA
  Title
Analysis of quorum-sensing-dependent control of rhizosphere-expressed (rhi) genes in Rhizobium leguminosarum bv. viciae.
  Journal
J Bacteriol 181:3816-23 (1999)
DOI:10.1128/JB.181.12.3816-3823.1999
Reference
  Authors
Lang J, Faure D
  Title
Functions and regulation of quorum-sensing in Agrobacterium tumefaciens.
  Journal
Front Plant Sci 5:14 (2014)
DOI:10.3389/fpls.2014.00014
Reference
  Authors
Planamente S, Morera S, Faure D
  Title
In planta fitness-cost of the Atu4232-regulon encoding for a selective GABA-binding sensor in Agrobacterium.
  Journal
Commun Integr Biol 6:e23692 (2013)
DOI:10.4161/cib.23692
Reference
  Authors
Barnard AM, Salmond GP
  Title
Quorum sensing in Erwinia species.
  Journal
Anal Bioanal Chem 387:415-23 (2007)
DOI:10.1007/s00216-006-0701-1
Reference
  Authors
Barnard AM, Bowden SD, Burr T, Coulthurst SJ, Monson RE, Salmond GP
  Title
Quorum sensing, virulence and secondary metabolite production in plant soft-rotting bacteria.
  Journal
Philos Trans R Soc Lond B Biol Sci 362:1165-83 (2007)
DOI:10.1098/rstb.2007.2042
Reference
  Authors
Carlier A, Burbank L, von Bodman SB
  Title
Identification and characterization of three novel EsaI/EsaR quorum-sensing controlled stewartan exopolysaccharide biosynthetic genes in Pantoea stewartii ssp. stewartii.
  Journal
Mol Microbiol 74:903-13 (2009)
DOI:10.1111/j.1365-2958.2009.06906.x
Reference
PMID:7665477
  Authors
Beck von Bodman S, Farrand SK
  Title
Capsular polysaccharide biosynthesis and pathogenicity in Erwinia stewartii require induction by an N-acylhomoserine lactone autoinducer.
  Journal
J Bacteriol 177:5000-8 (1995)
DOI:10.1128/JB.177.17.5000-5008.1995
Reference
  Authors
O'Grady EP, Viteri DF, Malott RJ, Sokol PA
  Title
Reciprocal regulation by the CepIR and CciIR quorum sensing systems in Burkholderia cenocepacia.
  Journal
BMC Genomics 10:441 (2009)
DOI:10.1186/1471-2164-10-441
Reference
  Authors
Malott RJ, Baldwin A, Mahenthiralingam E, Sokol PA
  Title
Characterization of the cciIR quorum-sensing system in Burkholderia cenocepacia.
  Journal
Infect Immun 73:4982-92 (2005)
DOI:10.1128/IAI.73.8.4982-4992.2005
Reference
  Authors
Deng Y, Schmid N, Wang C, Wang J, Pessi G, Wu D, Lee J, Aguilar C, Ahrens CH, Chang C, Song H, Eberl L, Zhang LH
  Title
Cis-2-dodecenoic acid receptor RpfR links quorum-sensing signal perception with regulation of virulence through cyclic dimeric guanosine monophosphate turnover.
  Journal
Proc Natl Acad Sci U S A 109:15479-84 (2012)
DOI:10.1073/pnas.1205037109
Reference
  Authors
Suppiger A, Schmid N, Aguilar C, Pessi G, Eberl L
  Title
Two quorum sensing systems control biofilm formation and virulence in members of the Burkholderia cepacia complex.
  Journal
Virulence 4:400-9 (2013)
DOI:10.4161/viru.25338
Reference
  Authors
Deng Y, Wu J, Tao F, Zhang LH
  Title
Listening to a new language: DSF-based quorum sensing in Gram-negative bacteria.
  Journal
Chem Rev 111:160-73 (2011)
DOI:10.1021/cr100354f
Reference
  Authors
Ryan RP, Dow JM
  Title
Communication with a growing family: diffusible signal factor (DSF) signaling in bacteria.
  Journal
Trends Microbiol 19:145-52 (2011)
DOI:10.1016/j.tim.2010.12.003
Reference
  Authors
Kim J, Kim JG, Kang Y, Jang JY, Jog GJ, Lim JY, Kim S, Suga H, Nagamatsu T, Hwang I
  Title
Quorum sensing and the LysR-type transcriptional activator ToxR regulate toxoflavin biosynthesis and transport in Burkholderia glumae.
  Journal
Mol Microbiol 54:921-34 (2004)
DOI:10.1111/j.1365-2958.2004.04338.x
Reference
  Authors
Kim J, Kang Y, Choi O, Jeong Y, Jeong JE, Lim JY, Kim M, Moon JS, Suga H, Hwang I
  Title
Regulation of polar flagellum genes is mediated by quorum sensing and FlhDC in Burkholderia glumae.
  Journal
Mol Microbiol 64:165-79 (2007)
DOI:10.1111/j.1365-2958.2007.05646.x
Reference
  Authors
Stauff DL, Bassler BL
  Title
Quorum sensing in Chromobacterium violaceum: DNA recognition and gene regulation by the CviR receptor.
  Journal
J Bacteriol 193:3871-8 (2011)
DOI:10.1128/JB.05125-11
Reference
  Authors
Chen G, Swem LR, Swem DL, Stauff DL, O'Loughlin CT, Jeffrey PD, Bassler BL, Hughson FM
  Title
A strategy for antagonizing quorum sensing.
  Journal
Mol Cell 42:199-209 (2011)
DOI:10.1016/j.molcel.2011.04.003
Reference
  Authors
Hao G, Burr TJ
  Title
Regulation of long-chain N-acyl-homoserine lactones in Agrobacterium vitis.
  Journal
J Bacteriol 188:2173-83 (2006)
DOI:10.1128/JB.188.6.2173-2183.2006
Reference
  Authors
Savka MA, Le PT, Burr TJ
  Title
LasR receptor for detection of long-chain quorum-sensing signals: identification of N-acyl-homoserine lactones encoded by the avsI locus of Agrobacterium vitis.
  Journal
Curr Microbiol 62:101-10 (2011)
DOI:10.1007/s00284-010-9679-1
Reference
  Authors
Le KY, Otto M
  Title
Quorum-sensing regulation in staphylococci-an overview.
  Journal
Front Microbiol 6:1174 (2015)
DOI:10.3389/fmicb.2015.01174
Reference
  Authors
Queck SY, Jameson-Lee M, Villaruz AE, Bach TH, Khan BA, Sturdevant DE, Ricklefs SM, Li M, Otto M
  Title
RNAIII-independent target gene control by the agr quorum-sensing system: insight into the evolution of virulence regulation in Staphylococcus aureus.
  Journal
Mol Cell 32:150-8 (2008)
DOI:10.1016/j.molcel.2008.08.005
Reference
  Authors
Darkoh C, DuPont HL, Norris SJ, Kaplan HB
  Title
Toxin synthesis by Clostridium difficile is regulated through quorum signaling.
  Journal
MBio 6:e02569 (2015)
DOI:10.1128/mBio.02569-14
Reference
  Authors
Vidal JE, Shak JR, Canizalez-Roman A
  Title
The CpAL quorum sensing system regulates production of hemolysins CPA and PFO to build Clostridium perfringens biofilms.
  Journal
Infect Immun 83:2430-42 (2015)
DOI:10.1128/IAI.00240-15
Reference
  Authors
Ohtani K, Yuan Y, Hassan S, Wang R, Wang Y, Shimizu T
  Title
Virulence gene regulation by the agr system in Clostridium perfringens.
  Journal
J Bacteriol 191:3919-27 (2009)
DOI:10.1128/JB.01455-08
Reference
  Authors
Li YH, Tian X
  Title
Quorum sensing and bacterial social interactions in biofilms.
  Journal
Sensors (Basel) 12:2519-38 (2012)
DOI:10.3390/s120302519
Reference
  Authors
Berg KH, Biornstad TJ, Johnsborg O, Havarstein LS
  Title
Properties and biological role of streptococcal fratricins.
  Journal
Appl Environ Microbiol 78:3515-22 (2012)
DOI:10.1128/AEM.00098-12
Reference
  Authors
Conrads G, de Soet JJ, Song L, Henne K, Sztajer H, Wagner-Dobler I, Zeng AP
  Title
Comparing the cariogenic species Streptococcus sobrinus and S. mutans on whole genome level.
  Journal
J Oral Microbiol 6:26189 (2014)
DOI:10.3402/jom.v6.26189
Reference
  Authors
Jimenez JC, Federle MJ
  Title
Quorum sensing in group A Streptococcus.
  Journal
Front Cell Infect Microbiol 4:127 (2014)
DOI:10.3389/fcimb.2014.00127
Reference
  Authors
Cook LC, Federle MJ
  Title
Peptide pheromone signaling in Streptococcus and Enterococcus.
  Journal
FEMS Microbiol Rev 38:473-92 (2014)
DOI:10.1111/1574-6976.12046
Reference
PMID:9680220
  Authors
Podbielski A, Leonard BA
  Title
The group A streptococcal dipeptide permease (Dpp) is involved in the uptake of essential amino acids and affects the expression of cysteine protease.
  Journal
Mol Microbiol 28:1323-34 (1998)
DOI:10.1046/j.1365-2958.1998.00898.x
Reference
PMID:8885277
  Authors
Podbielski A, Pohl B, Woischnik M, Korner C, Schmidt KH, Rozdzinski E, Leonard BA
  Title
Molecular characterization of group A streptococcal (GAS) oligopeptide permease (opp) and its effect on cysteine protease production.
  Journal
Mol Microbiol 21:1087-99 (1996)
DOI:10.1046/j.1365-2958.1996.661421.x
Reference
  Authors
Anbalagan S, Dmitriev A, McShan WM, Dunman PM, Chaussee MS
  Title
Growth phase-dependent modulation of Rgg binding specificity in Streptococcus pyogenes.
  Journal
J Bacteriol 194:3961-71 (2012)
DOI:10.1128/JB.06709-11
Reference
  Authors
Clewell DB
  Title
Tales of conjugation and sex pheromones: A plasmid and enterococcal odyssey.
  Journal
Mob Genet Elements 1:38-54 (2011)
DOI:10.4161/mge.1.1.15409
Reference
  Authors
Wardal E, Sadowy E, Hryniewicz W
  Title
Complex nature of enterococcal pheromone-responsive plasmids.
  Journal
Pol J Microbiol 59:79-87 (2010)
Reference
  Authors
Roux A, Payne SM, Gilmore MS
  Title
Microbial telesensing: probing the environment for friends, foes, and food.
  Journal
Cell Host Microbe 6:115-24 (2009)
DOI:10.1016/j.chom.2009.07.004
Reference
  Authors
Slamti L, Perchat S, Huillet E, Lereclus D
  Title
Quorum sensing in Bacillus thuringiensis is required for completion of a full infectious cycle in the insect.
  Journal
Toxins (Basel) 6:2239-55 (2014)
DOI:10.3390/toxins6082239
Reference
  Authors
Lopez D, Kolter R
  Title
Extracellular signals that define distinct and coexisting cell fates in Bacillus subtilis.
  Journal
FEMS Microbiol Rev 34:134-49 (2010)
DOI:10.1111/j.1574-6976.2009.00199.x
Reference
  Authors
Stephenson S, Mueller C, Jiang M, Perego M
  Title
Molecular analysis of Phr peptide processing in Bacillus subtilis.
  Journal
J Bacteriol 185:4861-71 (2003)
DOI:10.1128/JB.185.16.4861-4871.2003
Reference
  Authors
Lanigan-Gerdes S, Dooley AN, Faull KF, Lazazzera BA
  Title
Identification of subtilisin, Epr and Vpr as enzymes that produce CSF, an extracellular signalling peptide of Bacillus subtilis.
  Journal
Mol Microbiol 65:1321-33 (2007)
DOI:10.1111/j.1365-2958.2007.05869.x
Reference
  Authors
Kleerebezem M
  Title
Quorum sensing control of lantibiotic production; nisin and subtilin autoregulate their own biosynthesis.
  Journal
Peptides 25:1405-14 (2004)
DOI:10.1016/j.peptides.2003.10.021
Reference
  Authors
Rutherford ST, Bassler BL
  Title
Bacterial quorum sensing: its role in virulence and possibilities for its control.
  Journal
Cold Spring Harb Perspect Med 2:a012427 (2012)
DOI:10.1101/cshperspect.a012427
Reference
  Authors
LaSarre B, Federle MJ
  Title
Exploiting quorum sensing to confuse bacterial pathogens.
  Journal
Microbiol Mol Biol Rev 77:73-111 (2013)
DOI:10.1128/MMBR.00046-12
Reference
  Authors
Sifri CD
  Title
Healthcare epidemiology: quorum sensing: bacteria talk sense.
  Journal
Clin Infect Dis 47:1070-6 (2008)
DOI:10.1086/592072
Related
pathway
vpd00405  Phenazine biosynthesis
vpd02040  Flagellar assembly
KO pathway
ko02024   
LinkDB

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