KEGG Orthology (KO) - Ovis aries (sheep)

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     KO
 09100 Metabolism
 
   09101 Carbohydrate metabolism
 
   09102 Energy metabolism
 
   09103 Lipid metabolism
     00061 Fatty acid biosynthesis [PATH:oas00061]
     00062 Fatty acid elongation [PATH:oas00062]
     00071 Fatty acid degradation [PATH:oas00071]
     00072 Synthesis and degradation of ketone bodies [PATH:oas00072]
     00073 Cutin, suberine and wax biosynthesis
     00100 Steroid biosynthesis [PATH:oas00100]
     00120 Primary bile acid biosynthesis [PATH:oas00120]
     00121 Secondary bile acid biosynthesis
     00140 Steroid hormone biosynthesis [PATH:oas00140]
       100048994 CYP11A1; cholesterol side-chain cleavage enzyme, mitochondrial precursor
       105601846 CYP17; steroid 17-alpha-hydroxylase/17,20 lyase
       493968 CYP17A1; steroid 17-alpha-hydroxylase/17,20 lyase precursor
       101118590 STS; LOW QUALITY PROTEIN: steryl-sulfatase
       101122543 SULT2B1; sulfotransferase family cytosolic 2B member 1
       105612707 steroid 21-hydroxylase
       114108679 steroid 21-hydroxylase isoform X1
       100190978 HSD3B1; 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1
       100642181 SRD5A1; 3-oxo-5-alpha-steroid 4-dehydrogenase 1
       100820756 SRD5A2; 3-oxo-5-alpha-steroid 4-dehydrogenase 2
       101106772 SRD5A3; polyprenol reductase isoform X3
       101107541 dihydrodiol dehydrogenase 3-like isoform X1
       106990122 dihydrodiol dehydrogenase 3-like
       101109111 dihydrodiol dehydrogenase 3
       101109377 dihydrodiol dehydrogenase 3-like isoform X1
       101109633 dihydrodiol dehydrogenase 3-like
       443108 PGFS; prostaglandin F synthase 1 isoform X1
       101110434 dihydrodiol dehydrogenase 3-like isoform X1
       101107119 dihydrodiol dehydrogenase 3-like isoform X1
       105614315 prostaglandin F synthase 1-like
       101110693 LOW QUALITY PROTEIN: prostaglandin F synthase 1-like
       101106610 dihydrodiol dehydrogenase 3-like
       114108656 prostaglandin F synthase 1-like
       101107809 dihydrodiol dehydrogenase 3-like
       767576 CYP11B1; cytochrome P450 11B1, mitochondrial precursor
       101102377 cytochrome P450 11B1
       101103641 AKR1D1; 3-oxo-5-beta-steroid 4-dehydrogenase
       443409 HSD11B1; corticosteroid 11-beta-dehydrogenase isozyme 1
       101109443 HSD11B1L; hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X3
       443530 HSD11B2; corticosteroid 11-beta-dehydrogenase isozyme 2
       101119648 25-hydroxycholesterol 7-alpha-hydroxylase
       101120331 estrogen sulfotransferase
       101110778 HSD17B1; estradiol 17-beta-dehydrogenase 1
       100913161 HSD17B2; estradiol 17-beta-dehydrogenase 2
       101105400 17-beta-hydroxysteroid dehydrogenase type 6
       101110013 HSD17B7; 3-keto-steroid reductase isoform X1
       101116612 HSD17B8; estradiol 17-beta-dehydrogenase 8 isoform X1
       101112590 estradiol 17-beta-dehydrogenase 12-B-like
       101110086 HSD17B12; very-long-chain 3-oxoacyl-CoA reductase
       114109406 very-long-chain 3-oxoacyl-CoA reductase
       101109465 DHRS11; dehydrogenase/reductase SDR family member 11 isoform X1
       100170113 CYP1A1; cytochrome P450 1A1
       101109214 cytochrome P450 1A2
       105608805 cytochrome P450 2B4-like
       105614373 cytochrome P450 2B4-like isoform X1
       101107486 cytochrome P450 2C31-like
       101120535 LOW QUALITY PROTEIN: cytochrome P450 2C23-like
       101106641 cytochrome P450 2C19-like isoform X1
       100534653 CYP2C19; cytochrome P450 2C19
       101107056 cytochrome P450 2C19-like
       114108598 cytochrome P450 2C31-like
       100568290 CYP2C18; cytochrome P450 2C18
       114110259 cytochrome P450 2C18-like isoform X1
       100568286 CYP2D6; cytochrome P450 2D6
       101105651 cytochrome P450 2D14 isoform X1
       114114084 cytochrome P450 2D14-like isoform X1
       100170111 CYP3A24; cytochrome P450 3A24
       101110727 cytochrome P450 3A28
       101110202 cytochrome P450 3A24-like
       114108597 cytochrome P450 3A24-like
       100568285 CYP2E1; cytochrome P450 2E1
       101119706 cytochrome P450 1B1
       100144423 CYP19; aromatase
       101116841 cholesterol 7-alpha-monooxygenase
       442993 UGT1A9; UDP-glucuronosyltransferase 1-9 precursor
       100534643 UGT1A6; UDP-glucuronosyltransferase 1-6 precursor
       100534644 UGT1A1; UDP-glucuronosyltransferase 1-1 precursor
       100534645 UGT1A3; UDP-glucuronosyltransferase 1-3 precursor
       100534646 UGT1A4; UDP-glucuronosyltransferase 1-4 precursor
       100534650 UGT2B7; UDP-glucuronosyltransferase 2B7 precursor
       101116729 UDP-glucuronosyltransferase 2B31-like isoform X1
       101117163 UDP-glucuronosyltransferase 2B4-like isoform X1
       101117764 UDP-glucuronosyltransferase 2B4-like
       101122788 UDP-glucuronosyltransferase 2C1-like
       101119393 UDP-glucuronosyltransferase 2C1-like isoform X1
       101119640 UDP-glucuronosyltransferase 2A3 isoform X1
       114108654 UDP-glucuronosyltransferase 2A1-like isoform X1
       114115327 UDP-glucuronosyltransferase 2B4-like
       101118447 UDP-glucuronosyltransferase 2B4-like isoform X1
       101107004 UDP-glucuronosyltransferase 2C1-like
       101123042 UDP-glucuronosyltransferase 2C1-like isoform X1
       114115343 UDP-glucuronosyltransferase 2B4-like isoform X1
       114115345 UDP-glucuronosyltransferase 2B17-like isoform X1
       101118189 UDP-glucuronosyltransferase 2B4-like isoform X1
       101103091 TOMT; transmembrane O-methyltransferase
       114108863 COMT; catechol O-methyltransferase
       101111157 HSD17B3; testosterone 17-beta-dehydrogenase 3
K00498 CYP11A; cholesterol monooxygenase (side-chain-cleaving) [EC:1.14.15.6]
K00512 CYP17A; steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone deacetylase [EC:1.14.14.19 1.14.14.32]
K00512 CYP17A; steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone deacetylase [EC:1.14.14.19 1.14.14.32]
K01131 STS; steryl-sulfatase [EC:3.1.6.2]
K01015 SULT2B; alcohol sulfotransferase [EC:2.8.2.2]
K00513 CYP21A; steroid 21-monooxygenase [EC:1.14.14.16]
K00513 CYP21A; steroid 21-monooxygenase [EC:1.14.14.16]
K00070 HSD3B; 3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:1.1.1.145 5.3.3.1]
K12343 SRD5A1; 3-oxo-5-alpha-steroid 4-dehydrogenase 1 [EC:1.3.1.22]
K12344 SRD5A2; 3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:1.3.1.22]
K12345 SRD5A3; 3-oxo-5-alpha-steroid 4-dehydrogenase 3 / polyprenol reductase [EC:1.3.1.22 1.3.1.94]
K04119 AKR1C3; aldo-keto reductase family 1 member C3 [EC:1.1.1.51 1.1.1.188 1.1.1.213 1.1.1.357]
K04119 AKR1C3; aldo-keto reductase family 1 member C3 [EC:1.1.1.51 1.1.1.188 1.1.1.213 1.1.1.357]
K04119 AKR1C3; aldo-keto reductase family 1 member C3 [EC:1.1.1.51 1.1.1.188 1.1.1.213 1.1.1.357]
K04119 AKR1C3; aldo-keto reductase family 1 member C3 [EC:1.1.1.51 1.1.1.188 1.1.1.213 1.1.1.357]
K04119 AKR1C3; aldo-keto reductase family 1 member C3 [EC:1.1.1.51 1.1.1.188 1.1.1.213 1.1.1.357]
K04119 AKR1C3; aldo-keto reductase family 1 member C3 [EC:1.1.1.51 1.1.1.188 1.1.1.213 1.1.1.357]
K04119 AKR1C3; aldo-keto reductase family 1 member C3 [EC:1.1.1.51 1.1.1.188 1.1.1.213 1.1.1.357]
K04119 AKR1C3; aldo-keto reductase family 1 member C3 [EC:1.1.1.51 1.1.1.188 1.1.1.213 1.1.1.357]
K04119 AKR1C3; aldo-keto reductase family 1 member C3 [EC:1.1.1.51 1.1.1.188 1.1.1.213 1.1.1.357]
K04119 AKR1C3; aldo-keto reductase family 1 member C3 [EC:1.1.1.51 1.1.1.188 1.1.1.213 1.1.1.357]
K04119 AKR1C3; aldo-keto reductase family 1 member C3 [EC:1.1.1.51 1.1.1.188 1.1.1.213 1.1.1.357]
K04119 AKR1C3; aldo-keto reductase family 1 member C3 [EC:1.1.1.51 1.1.1.188 1.1.1.213 1.1.1.357]
K04119 AKR1C3; aldo-keto reductase family 1 member C3 [EC:1.1.1.51 1.1.1.188 1.1.1.213 1.1.1.357]
K00497 CYP11B1; steroid 11beta-monooxygenase [EC:1.14.15.4]
K00497 CYP11B1; steroid 11beta-monooxygenase [EC:1.14.15.4]
K00251 AKR1D1; 3-oxo-5-beta-steroid 4-dehydrogenase [EC:1.3.1.3]
K15680 HSD11B1; corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:1.1.1.146]
K15680 HSD11B1; corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:1.1.1.146]
K00071 HSD11B2; corticosteroid 11-beta-dehydrogenase isozyme 2 [EC:1.1.1.-]
K07430 CYP7B; 25/26-hydroxycholesterol 7alpha-hydroxylase [EC:1.14.14.29]
K01016 SULT1E1; estrone sulfotransferase [EC:2.8.2.4]
K00044 HSD17B1; 17beta-estradiol 17-dehydrogenase [EC:1.1.1.62]
K13368 HSD17B2; 17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:1.1.1.62 1.1.1.239]
K13369 HSD17B6; 17beta-estradiol 17-dehydrogenase / all-trans-retinol dehydrogenase (NAD+) / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:1.1.1.62 1.1.1.105 1.1.1.239]
K13373 HSD17B7; 17beta-estradiol 17-dehydrogenase / 3beta-hydroxysteroid 3-dehydrogenase [EC:1.1.1.62 1.1.1.270]
K13370 HSD17B8; 17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) / 3-oxoacyl-[acyl-carrier protein] reductase alpha subunit [EC:1.1.1.62 1.1.1.239]
K10251 HSD17B12; 17beta-estradiol 17-dehydrogenase / very-long-chain 3-oxoacyl-CoA reductase [EC:1.1.1.62 1.1.1.330]
K10251 HSD17B12; 17beta-estradiol 17-dehydrogenase / very-long-chain 3-oxoacyl-CoA reductase [EC:1.1.1.62 1.1.1.330]
K10251 HSD17B12; 17beta-estradiol 17-dehydrogenase / very-long-chain 3-oxoacyl-CoA reductase [EC:1.1.1.62 1.1.1.330]
K22970 DHRS11; 17beta-estradiol 17-dehydrogenase / 3beta-hydroxysteroid 3-dehydrogenase [EC:1.1.1.62 1.1.1.270]
K07408 CYP1A1; cytochrome P450 family 1 subfamily A1 [EC:1.14.14.1]
K07409 CYP1A2; cytochrome P450 family 1 subfamily A2 [EC:1.14.14.1]
K07412 CYP2B; cytochrome P450 family 2 subfamily B [EC:1.14.14.1]
K07412 CYP2B; cytochrome P450 family 2 subfamily B [EC:1.14.14.1]
K07413 CYP2C; cytochrome P450 family 2 subfamily C [EC:1.14.14.1]
K07413 CYP2C; cytochrome P450 family 2 subfamily C [EC:1.14.14.1]
K07413 CYP2C; cytochrome P450 family 2 subfamily C [EC:1.14.14.1]
K07413 CYP2C; cytochrome P450 family 2 subfamily C [EC:1.14.14.1]
K07413 CYP2C; cytochrome P450 family 2 subfamily C [EC:1.14.14.1]
K07413 CYP2C; cytochrome P450 family 2 subfamily C [EC:1.14.14.1]
K07413 CYP2C; cytochrome P450 family 2 subfamily C [EC:1.14.14.1]
K07413 CYP2C; cytochrome P450 family 2 subfamily C [EC:1.14.14.1]
K07414 CYP2D; cytochrome P450 family 2 subfamily D [EC:1.14.14.1]
K07414 CYP2D; cytochrome P450 family 2 subfamily D [EC:1.14.14.1]
K07414 CYP2D; cytochrome P450 family 2 subfamily D [EC:1.14.14.1]
K07424 CYP3A; cytochrome P450 family 3 subfamily A [EC:1.14.14.1]
K07424 CYP3A; cytochrome P450 family 3 subfamily A [EC:1.14.14.1]
K07424 CYP3A; cytochrome P450 family 3 subfamily A [EC:1.14.14.1]
K07424 CYP3A; cytochrome P450 family 3 subfamily A [EC:1.14.14.1]
K07415 CYP2E1; cytochrome P450 family 2 subfamily E1 [EC:1.14.14.-]
K07410 CYP1B1; cytochrome P450 family 1 subfamily B1 [EC:1.14.14.1]
K07434 CYP19A; aromatase [EC:1.14.14.14]
K00489 CYP7A1; cholesterol 7alpha-monooxygenase [EC:1.14.14.23]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00545 COMT; catechol O-methyltransferase [EC:2.1.1.6]
K00545 COMT; catechol O-methyltransferase [EC:2.1.1.6]
K10207 HSD17B3; testosterone 17beta-dehydrogenase (NADP+) [EC:1.1.1.64]
     00561 Glycerolipid metabolism [PATH:oas00561]
     00564 Glycerophospholipid metabolism [PATH:oas00564]
     00565 Ether lipid metabolism [PATH:oas00565]
     00600 Sphingolipid metabolism [PATH:oas00600]
     00590 Arachidonic acid metabolism [PATH:oas00590]
     00591 Linoleic acid metabolism [PATH:oas00591]
     00592 alpha-Linolenic acid metabolism [PATH:oas00592]
     01040 Biosynthesis of unsaturated fatty acids [PATH:oas01040]
 
   09104 Nucleotide metabolism
 
   09105 Amino acid metabolism
 
   09106 Metabolism of other amino acids
 
   09107 Glycan biosynthesis and metabolism
 
   09108 Metabolism of cofactors and vitamins
 
   09109 Metabolism of terpenoids and polyketides
 
   09110 Biosynthesis of other secondary metabolites
 
   09111 Xenobiotics biodegradation and metabolism
 
   09112 Not included in regular maps
 
 09120 Genetic Information Processing
 
 09130 Environmental Information Processing
 
 09140 Cellular Processes
 
 09150 Organismal Systems
 
 09160 Human Diseases
 
   09161 Cancer: overview
 
   09162 Cancer: specific types
     05210 Colorectal cancer [PATH:oas05210]
     05212 Pancreatic cancer [PATH:oas05212]
     05225 Hepatocellular carcinoma [PATH:oas05225]
     05226 Gastric cancer [PATH:oas05226]
     05214 Glioma [PATH:oas05214]
     05216 Thyroid cancer [PATH:oas05216]
     05221 Acute myeloid leukemia [PATH:oas05221]
     05220 Chronic myeloid leukemia [PATH:oas05220]
     05217 Basal cell carcinoma [PATH:oas05217]
     05218 Melanoma [PATH:oas05218]
     05211 Renal cell carcinoma [PATH:oas05211]
     05219 Bladder cancer [PATH:oas05219]
     05215 Prostate cancer [PATH:oas05215]
       105607169 glutathione S-transferase P
       114116112 glutathione S-transferase P-like
       101120874 GSTP1; glutathione S-transferase P
       100127219 CDKN1B; cyclin-dependent kinase inhibitor 1B
       100216433 CDK2; cyclin-dependent kinase 2
       101109811 CCNE2; G1/S-specific cyclin-E2
       101107124 CCNE1; G1/S-specific cyclin-E1
       100144755 RB1; retinoblastoma-associated protein
       101117526 E2F1; transcription factor E2F1
       105606975 E2F2; transcription factor E2F2
       101121809 E2F3; transcription factor E2F3
       101120216 TMPRSS2; transmembrane protease serine 2
       101110646 ERG; transcriptional regulator ERG isoform X1
       100302501 PLAU; urokinase-type plasminogen activator precursor
       101118332 PLAT; tissue-type plasminogen activator
       101118895 stromelysin-1
       100192422 MMP9; matrix metalloproteinase-9
       101115891 ZEB1; zinc finger E-box-binding homeobox 1 isoform X1
       101103308 IL1R2; interleukin-1 receptor type 2
       101111287 SPINT1; kunitz-type protease inhibitor 1 isoform X2
       101115418 ETV5; ETS translocation variant 5 isoform X1
       114110121 INS; insulin
       114110564 PDGFA; platelet-derived growth factor subunit A isoform X1
       443545 PDGFB; platelet-derived growth factor subunit B precursor
       101117784 PDGFD; platelet-derived growth factor D isoform X1
       101112600 PDGFC; platelet-derived growth factor C isoform X1
       101106508 TGFA; protransforming growth factor alpha
       443318 IGF1; insulin-like growth factor I precursor
       101108266 INSRR; insulin receptor-related protein
       101106012 PDGFRA; platelet-derived growth factor receptor alpha
       101122783 PDGFRB; LOW QUALITY PROTEIN: platelet-derived growth factor receptor beta
       780507 FGFR1; fibroblast growth factor receptor 1 isoform X1
       443548 FGFR2; fibroblast growth factor receptor 2 isoform X3
       780479 EGFR; epidermal growth factor receptor
       780519 ERBB2; receptor tyrosine-protein kinase erbB-2
       443515 IGF1R; insulin-like growth factor 1 receptor
       101109759 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
       101110015 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
       101117348 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1
       101123247 PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma
       101111546 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta isoform X1
       101121455 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X2
       101119351 PTEN; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X2
       101117211 PDPK1; 3-phosphoinositide-dependent protein kinase 1
       101113199 NKX3-1; homeobox protein Nkx-3.1
       101118462 AKT3; RAC-gamma serine/threonine-protein kinase
       101119242 AKT2; RAC-beta serine/threonine-protein kinase
       100294652 AKT1; RAC-alpha serine/threonine-protein kinase
       101110953 CASP9; caspase-9
       780444 BAD; bcl2-associated agonist of cell death
       101107877 FOXO1; forkhead box protein O1
       100302083 CDKN1A; cyclin-dependent kinase inhibitor 1
       101104979 MDM2; E3 ubiquitin-protein ligase Mdm2
       101103187 E3 ubiquitin-protein ligase Mdm2-like
       443421 TP53; cellular tumor antigen p53
       100169938 GSK3B; glycogen synthase kinase-3 beta
       443118 CREB1; cyclic AMP-responsive element-binding protein 1 isoform X2
       100216465 ATF4; cyclic AMP-dependent transcription factor ATF-4
       101107485 CREB3L4; cyclic AMP-responsive element-binding protein 3-like protein 4 isoform X2
       101114243 CREB3; cyclic AMP-responsive element-binding protein 3 isoform X2
       101108743 CREB3L2; cyclic AMP-responsive element-binding protein 3-like protein 2
       101113586 CREB3L3; cyclic AMP-responsive element-binding protein 3-like protein 3 isoform X1
       101113882 CREB3L1; cyclic AMP-responsive element-binding protein 3-like protein 1 isoform X1
       101112976 CREB5; cyclic AMP-responsive element-binding protein 5 isoform X2
       100294600 CTNNB1; catenin beta-1
       101110136 EP300; LOW QUALITY PROTEIN: histone acetyltransferase p300
       101123600 CREBBP; CREB-binding protein
       101101980 TCF7; transcription factor 7 isoform X1
       100913162 TCF7L1; transcription factor 7-like 1
       101118068 TCF7L2; LOW QUALITY PROTEIN: transcription factor 7-like 2
       780521 LEF1; lymphoid enhancer-binding factor 1 isoform X2
       100144763 CCND1; G1/S-specific cyclin-D1
       101111143 CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1
       780484 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1
       101107332 IKBKG; NF-kappa-B essential modulator isoform X1
       780520 NFKBIA; NF-kappa-B inhibitor alpha
       101108228 NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1
       101102191 RELA; transcription factor p65
       101119602 BCL2; apoptosis regulator Bcl-2
       100271659 MTOR; serine/threonine-protein kinase mTOR
       101109893 GRB2; growth factor receptor-bound protein 2
       114110058 growth factor receptor-bound protein 2
       101118865 SOS1; son of sevenless homolog 1 isoform X1
       101102732 SOS2; son of sevenless homolog 2
       101104357 HRAS; GTPase HRas isoform X1
       114114919 GTPase HRas-like
       101114005 KRAS; GTPase KRas isoform X1
       101102438 NRAS; GTPase NRas
       100305131 ARAF; serine/threonine-protein kinase A-Raf
       101107438 BRAF; serine/threonine-protein kinase B-raf isoform X2
       101103190 RAF1; RAF proto-oncogene serine/threonine-protein kinase
       101123635 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 isoform X2
       101113846 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2 isoform X1
       101115485 MAPK1; mitogen-activated protein kinase 1
       101123008 MAPK3; mitogen-activated protein kinase 3
       100820756 SRD5A2; 3-oxo-5-alpha-steroid 4-dehydrogenase 2
       443042 AR; androgen receptor
       100127209 HSP90AA1; heat shock protein HSP 90-alpha
       101117797 HSP90AB1; heat shock protein HSP 90-beta
       101111703 HSP90B1; endoplasmin
K23790 GSTP; glutathione S-transferase P [EC:2.5.1.18]
K23790 GSTP; glutathione S-transferase P [EC:2.5.1.18]
K23790 GSTP; glutathione S-transferase P [EC:2.5.1.18]
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K09633 TMPRSS2; transmembrane protease serine 2 [EC:3.4.21.-]
K09435 ERG; transcriptional regulator ERG
K01348 PLAU; urokinase plasminogen activator [EC:3.4.21.73]
K01343 PLAT; tissue plasminogen activator [EC:3.4.21.68]
K01394 MMP3; matrix metalloproteinase-3 (stromelysin 1, progelatinase) [EC:3.4.24.17]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K09299 ZEB1; zinc finger homeobox protein 1
K04387 IL1R2; interleukin 1 receptor type II
K15619 SPINT1; Kunitz-type protease inhibitor 1
K15593 ETV5; ets translocation variant 5
K04526 INS; insulin
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K05450 PDGFC_D; platelet derived growth factor C/D
K05450 PDGFC_D; platelet derived growth factor C/D
K08774 TGFA; transforming growth factor, alpha
K05459 IGF1; insulin-like growth factor 1
K05086 INSRR; insulin receptor-related receptor [EC:2.7.10.1]
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K09348 NKX3-1; homeobox protein Nkx-3.1
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02158 BAD; Bcl-2-antagonist of cell death
K07201 FOXO1; forkhead box protein O1
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53; tumor protein p53
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04374 ATF4; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5; cyclic AMP-responsive element-binding protein 5
K02105 CTNNB1; catenin beta 1
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K04503 CCND1; G1/S-specific cyclin-D1
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K02161 BCL2; apoptosis regulator Bcl-2
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04364 GRB2; growth factor receptor-bound protein 2
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K12344 SRD5A2; 3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:1.3.1.22]
K08557 AR; androgen receptor
K04079 HSP90A; molecular chaperone HtpG
K04079 HSP90A; molecular chaperone HtpG
K09487 HSP90B; heat shock protein 90kDa beta
     05213 Endometrial cancer [PATH:oas05213]
     05224 Breast cancer [PATH:oas05224]
     05222 Small cell lung cancer [PATH:oas05222]
     05223 Non-small cell lung cancer [PATH:oas05223]
 
   09172 Infectious disease: viral
 
   09171 Infectious disease: bacterial
 
   09174 Infectious disease: parasitic
 
   09163 Immune disease
 
   09164 Neurodegenerative disease
 
   09165 Substance dependence
 
   09166 Cardiovascular disease
 
   09167 Endocrine and metabolic disease
 
   09175 Drug resistance: antimicrobial
 
   09176 Drug resistance: antineoplastic
 
 09180 Brite Hierarchies
 
 09190 Not Included in Pathway or Brite

[ KO | BRITE | KEGG2 | KEGG ]
Last updated: March 2, 2021