|
KO |
09100 Metabolism
|
|
|
09101 Carbohydrate metabolism
|
|
|
09102 Energy metabolism
|
|
|
09103 Lipid metabolism
|
00061 Fatty acid biosynthesis [PATH:oas00061]
|
00062 Fatty acid elongation [PATH:oas00062]
|
00071 Fatty acid degradation [PATH:oas00071]
|
00073 Cutin, suberine and wax biosynthesis
|
00074 Mycolic acid biosynthesis
|
00100 Steroid biosynthesis [PATH:oas00100]
|
00120 Primary bile acid biosynthesis [PATH:oas00120]
|
00121 Secondary bile acid biosynthesis
|
00140 Steroid hormone biosynthesis [PATH:oas00140]
|
100048994 CYP11A1; cholesterol side-chain cleavage enzyme, mitochondrial precursor
105601846 CYP17; steroid 17-alpha-hydroxylase/17,20 lyase
493968 CYP17A1; steroid 17-alpha-hydroxylase/17,20 lyase precursor
101118590 steryl-sulfatase isoform X1
101122543 SULT2B1; sulfotransferase 2B1
105612707 steroid 21-hydroxylase isoform X1
114108679 steroid 21-hydroxylase isoform X1
100190978 HSD3B1; 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1
100642181 SRD5A1; 3-oxo-5-alpha-steroid 4-dehydrogenase 1
100820756 SRD5A2; 3-oxo-5-alpha-steroid 4-dehydrogenase 2 isoform X2
101106772 SRD5A3; polyprenol reductase
101107119 dihydrodiol dehydrogenase 3-like
101107541 dihydrodiol dehydrogenase 3-like isoform X1
101109111 dihydrodiol dehydrogenase 3 isoform X1
101109377 dihydrodiol dehydrogenase 3-like isoform X1
101110434 dihydrodiol dehydrogenase 3-like isoform X1
101110693 LOW QUALITY PROTEIN: prostaglandin F synthase 1-like
105614315 dihydrodiol dehydrogenase 3-like isoform X1
106990122 dihydrodiol dehydrogenase 3-like
114108656 prostaglandin F synthase 1-like isoform X1
101102377 cytochrome P450 11B1, mitochondrial isoform X4
767576 CYP11B1; cytochrome P450 11B1, mitochondrial precursor
101103641 AKR1D1; aldo-keto reductase family 1 member D1
101109443 HSD11B1L; hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X3
443409 HSD11B1; 11-beta-hydroxysteroid dehydrogenase 1
443530 HSD11B2; 11-beta-hydroxysteroid dehydrogenase type 2
101119648 cytochrome P450 7B1
101120331 sulfotransferase 1E1
101110778 HSD17B1; 17-beta-hydroxysteroid dehydrogenase type 1
100913161 HSD17B2; 17-beta-hydroxysteroid dehydrogenase type 2
101105400 17-beta-hydroxysteroid dehydrogenase type 6 isoform X2
101110013 HSD17B7; 3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7 isoform X3
101116612 HSD17B8; (3R)-3-hydroxyacyl-CoA dehydrogenase
101110086 HSD17B12; very-long-chain 3-oxoacyl-CoA reductase
101112590 estradiol 17-beta-dehydrogenase 12-B-like
101109465 DHRS11; dehydrogenase/reductase SDR family member 11
100170113 CYP1A1; cytochrome P450 1A1
101109214 cytochrome P450 1A2
105614373 cytochrome P450 2B11-like isoform X1
114117814 cytochrome P450 2B4-like isoform X1
114117992 cytochrome P450 2B11-like
100534653 CYP2C19; cytochrome P450 2C19
100568290 CYP2C18; cytochrome P450 2C18 isoform X2
101106641 cytochrome P450 2C19-like isoform X2
101107056 cytochrome P450 2C19-like
101107486 cytochrome P450 2C31-like isoform X1
101120535 LOW QUALITY PROTEIN: cytochrome P450 2C23-like
100568286 CYP2D6; cytochrome P450 2D6
101112384 cytochrome P450 2D14-like isoform X1
114114084 cytochrome P450 2D14-like isoform X1
114114086 cytochrome P450 2D14-like isoform X1
100170111 CYP3A24; cytochrome P450 3A24
101110202 cytochrome P450 3A24-like
101110727 cytochrome P450 3A28 isoform X1
114108597 cytochrome P450 3A24-like isoform X1
100568285 CYP2E1; cytochrome P450 2E1
101119706 cytochrome P450 1B1
100144423 CYP19; aromatase
101116841 cytochrome P450 7A1
101122787 HSD17B11; LOW QUALITY PROTEIN: estradiol 17-beta-dehydrogenase 11
100534643 UGT1A6; UDP-glucuronosyltransferase 1-6 precursor
100534644 UGT1A1; UDP-glucuronosyltransferase 1A1 precursor
100534645 UGT1A3; UDP-glucuronosyltransferase 1-3 precursor
100534646 UGT1A4; UDP-glucuronosyltransferase 1-4 precursor
100534650 UGT2B7; UDP-glucuronosyltransferase 2B7 precursor
101116729 UDP-glucuronosyltransferase 2B31-like
101117163 UDP-glucuronosyltransferase 2B4-like isoform X2
101117764 UDP-glucuronosyltransferase 2B4-like
101118189 UDP-glucuronosyltransferase 2B4-like
101118447 UDP-glucuronosyltransferase 2B4-like isoform X1
101119393 UDP-glucuronosyltransferase 2C1-like isoform X1
101119640 UDP-glucuronosyltransferase 2A3 isoform X1
101122788 UDP-glucuronosyltransferase 2C1-like isoform X4
101123042 UDP-glucuronosyltransferase 2C1-like isoform X1
114112219 UDP-glucuronosyltransferase 2B4-like isoform X1
114115345 UDP-glucuronosyltransferase 2B4-like isoform X1
121816013 UDP-glucuronosyltransferase 2B4-like isoform X1
442993 UGT1A9; UDP-glucuronosyltransferase 1-9 precursor
101103091 TOMT; transmembrane O-methyltransferase
114108863 COMT; catechol O-methyltransferase
101111157 HSD17B3; 17-beta-hydroxysteroid dehydrogenase type 3 isoform X1
|
K00498 CYP11A; cholesterol monooxygenase (side-chain-cleaving) [EC:1.14.15.6]
K00512 CYP17A; steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone deacetylase [EC:1.14.14.19 1.14.14.32]
K00512 CYP17A; steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone deacetylase [EC:1.14.14.19 1.14.14.32]
K01131 STS; steryl-sulfatase [EC:3.1.6.2]
K01015 SULT2B; alcohol sulfotransferase [EC:2.8.2.2]
K00513 CYP21A; steroid 21-monooxygenase [EC:1.14.14.16]
K00513 CYP21A; steroid 21-monooxygenase [EC:1.14.14.16]
K00070 HSD3B; 3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:1.1.1.145 5.3.3.1]
K12343 SRD5A1; 3-oxo-5-alpha-steroid 4-dehydrogenase 1 [EC:1.3.1.22]
K12344 SRD5A2; 3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:1.3.1.22]
K12345 SRD5A3; 3-oxo-5-alpha-steroid 4-dehydrogenase 3 / polyprenol reductase [EC:1.3.1.22 1.3.1.94]
K04119 AKR1C3; aldo-keto reductase family 1 member C3 [EC:1.1.1.51 1.1.1.188 1.1.1.213 1.1.1.357]
K04119 AKR1C3; aldo-keto reductase family 1 member C3 [EC:1.1.1.51 1.1.1.188 1.1.1.213 1.1.1.357]
K04119 AKR1C3; aldo-keto reductase family 1 member C3 [EC:1.1.1.51 1.1.1.188 1.1.1.213 1.1.1.357]
K04119 AKR1C3; aldo-keto reductase family 1 member C3 [EC:1.1.1.51 1.1.1.188 1.1.1.213 1.1.1.357]
K04119 AKR1C3; aldo-keto reductase family 1 member C3 [EC:1.1.1.51 1.1.1.188 1.1.1.213 1.1.1.357]
K04119 AKR1C3; aldo-keto reductase family 1 member C3 [EC:1.1.1.51 1.1.1.188 1.1.1.213 1.1.1.357]
K04119 AKR1C3; aldo-keto reductase family 1 member C3 [EC:1.1.1.51 1.1.1.188 1.1.1.213 1.1.1.357]
K04119 AKR1C3; aldo-keto reductase family 1 member C3 [EC:1.1.1.51 1.1.1.188 1.1.1.213 1.1.1.357]
K04119 AKR1C3; aldo-keto reductase family 1 member C3 [EC:1.1.1.51 1.1.1.188 1.1.1.213 1.1.1.357]
K00497 CYP11B1; steroid 11beta-monooxygenase [EC:1.14.15.4]
K00497 CYP11B1; steroid 11beta-monooxygenase [EC:1.14.15.4]
K00251 AKR1D1; 3-oxo-5-beta-steroid 4-dehydrogenase [EC:1.3.1.3]
K15680 HSD11B1; corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:1.1.1.146]
K15680 HSD11B1; corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:1.1.1.146]
K00071 HSD11B2; corticosteroid 11-beta-dehydrogenase isozyme 2 [EC:1.1.1.-]
K07430 CYP7B; 25/26-hydroxycholesterol 7alpha-hydroxylase [EC:1.14.14.29]
K01016 SULT1E1; estrone sulfotransferase [EC:2.8.2.4]
K00044 HSD17B1; 17beta-estradiol 17-dehydrogenase [EC:1.1.1.62]
K13368 HSD17B2; 17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:1.1.1.62 1.1.1.239]
K13369 HSD17B6; 17beta-estradiol 17-dehydrogenase / all-trans-retinol dehydrogenase (NAD+) / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:1.1.1.62 1.1.1.105 1.1.1.239]
K13373 HSD17B7; 17beta-estradiol 17-dehydrogenase / 3beta-hydroxysteroid 3-dehydrogenase [EC:1.1.1.62 1.1.1.270]
K13370 HSD17B8; 17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) / 3-oxoacyl-[acyl-carrier protein] reductase alpha subunit [EC:1.1.1.62 1.1.1.239]
K10251 HSD17B12; 17beta-estradiol 17-dehydrogenase / very-long-chain 3-oxoacyl-CoA reductase [EC:1.1.1.62 1.1.1.330]
K10251 HSD17B12; 17beta-estradiol 17-dehydrogenase / very-long-chain 3-oxoacyl-CoA reductase [EC:1.1.1.62 1.1.1.330]
K22970 DHRS11; 17beta-estradiol 17-dehydrogenase / 3beta-hydroxysteroid 3-dehydrogenase [EC:1.1.1.62 1.1.1.270]
K07408 CYP1A1; cytochrome P450 family 1 subfamily A1 [EC:1.14.14.1]
K07409 CYP1A2; cytochrome P450 family 1 subfamily A2 [EC:1.14.14.1]
K07412 CYP2B; cytochrome P450 family 2 subfamily B [EC:1.14.14.1]
K07412 CYP2B; cytochrome P450 family 2 subfamily B [EC:1.14.14.1]
K07412 CYP2B; cytochrome P450 family 2 subfamily B [EC:1.14.14.1]
K07413 CYP2C; cytochrome P450 family 2 subfamily C [EC:1.14.14.1]
K07413 CYP2C; cytochrome P450 family 2 subfamily C [EC:1.14.14.1]
K07413 CYP2C; cytochrome P450 family 2 subfamily C [EC:1.14.14.1]
K07413 CYP2C; cytochrome P450 family 2 subfamily C [EC:1.14.14.1]
K07413 CYP2C; cytochrome P450 family 2 subfamily C [EC:1.14.14.1]
K07413 CYP2C; cytochrome P450 family 2 subfamily C [EC:1.14.14.1]
K07414 CYP2D; cytochrome P450 family 2 subfamily D [EC:1.14.14.1]
K07414 CYP2D; cytochrome P450 family 2 subfamily D [EC:1.14.14.1]
K07414 CYP2D; cytochrome P450 family 2 subfamily D [EC:1.14.14.1]
K07414 CYP2D; cytochrome P450 family 2 subfamily D [EC:1.14.14.1]
K07424 CYP3A; cytochrome P450 family 3 subfamily A [EC:1.14.14.1]
K07424 CYP3A; cytochrome P450 family 3 subfamily A [EC:1.14.14.1]
K07424 CYP3A; cytochrome P450 family 3 subfamily A [EC:1.14.14.1]
K07424 CYP3A; cytochrome P450 family 3 subfamily A [EC:1.14.14.1]
K07415 CYP2E1; cytochrome P450 family 2 subfamily E1 [EC:1.14.14.-]
K07410 CYP1B1; cytochrome P450 family 1 subfamily B1 [EC:1.14.14.1]
K07434 CYP19A; aromatase [EC:1.14.14.14]
K00489 CYP7A1; cholesterol 7alpha-monooxygenase [EC:1.14.14.23]
K25779 HSD17B11; hydroxysteroid 17beta dehydrogenase 11 [EC:1.1.1.-]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00699 UGT; glucuronosyltransferase [EC:2.4.1.17]
K00545 COMT; catechol O-methyltransferase [EC:2.1.1.6]
K00545 COMT; catechol O-methyltransferase [EC:2.1.1.6]
K10207 HSD17B3; testosterone 17beta-dehydrogenase (NADP+) [EC:1.1.1.64]
|
00561 Glycerolipid metabolism [PATH:oas00561]
|
00564 Glycerophospholipid metabolism [PATH:oas00564]
|
00565 Ether lipid metabolism [PATH:oas00565]
|
00600 Sphingolipid metabolism [PATH:oas00600]
|
00590 Arachidonic acid metabolism [PATH:oas00590]
|
00591 Linoleic acid metabolism [PATH:oas00591]
|
00592 alpha-Linolenic acid metabolism [PATH:oas00592]
|
01040 Biosynthesis of unsaturated fatty acids [PATH:oas01040]
|
|
|
09104 Nucleotide metabolism
|
|
|
09105 Amino acid metabolism
|
|
|
09106 Metabolism of other amino acids
|
|
|
09107 Glycan biosynthesis and metabolism
|
|
|
09108 Metabolism of cofactors and vitamins
|
|
|
09109 Metabolism of terpenoids and polyketides
|
|
|
09110 Biosynthesis of other secondary metabolites
|
|
|
09111 Xenobiotics biodegradation and metabolism
|
|
|
09112 Not included in regular maps
|
|
|
09120 Genetic Information Processing
|
|
|
09130 Environmental Information Processing
|
|
|
09140 Cellular Processes
|
|
|
09150 Organismal Systems
|
|
|
09160 Human Diseases
|
|
|
09161 Cancer: overview
|
|
|
09162 Cancer: specific types
|
05210 Colorectal cancer [PATH:oas05210]
|
05212 Pancreatic cancer [PATH:oas05212]
|
05225 Hepatocellular carcinoma [PATH:oas05225]
|
05226 Gastric cancer [PATH:oas05226]
|
05214 Glioma [PATH:oas05214]
|
05216 Thyroid cancer [PATH:oas05216]
|
05221 Acute myeloid leukemia [PATH:oas05221]
|
05220 Chronic myeloid leukemia [PATH:oas05220]
|
05217 Basal cell carcinoma [PATH:oas05217]
|
05218 Melanoma [PATH:oas05218]
|
05211 Renal cell carcinoma [PATH:oas05211]
|
05219 Bladder cancer [PATH:oas05219]
|
05215 Prostate cancer [PATH:oas05215]
|
101120874 glutathione S-transferase P
105607169 glutathione S-transferase P
100127219 CDKN1B; cyclin-dependent kinase inhibitor 1B
100216433 CDK2; cyclin-dependent kinase 2
101107124 CCNE1; G1/S-specific cyclin-E1 isoform X2
101109811 CCNE2; G1/S-specific cyclin-E2 isoform X1
100144755 RB1; retinoblastoma-associated protein isoform X1
101117526 E2F1; transcription factor E2F1
105606975 E2F2; transcription factor E2F2
101121809 E2F3; transcription factor E2F3 isoform X1
101120216 TMPRSS2; transmembrane protease serine 2 isoform X2
101110646 ERG; transcriptional regulator ERG isoform X1
100302501 PLAU; urokinase-type plasminogen activator precursor
101118332 PLAT; tissue-type plasminogen activator
101118895 stromelysin-1
100192422 MMP9; matrix metalloproteinase-9
101115891 ZEB1; zinc finger E-box-binding homeobox 1 isoform X1
101103308 IL1R2; interleukin-1 receptor type 2 isoform X3
101111287 SPINT1; kunitz-type protease inhibitor 1 isoform X2
101115418 ETV5; ETS translocation variant 5 isoform X4
114110121 INS; insulin
114110564 PDGFA; platelet-derived growth factor subunit A isoform X2
443545 PDGFB; platelet-derived growth factor subunit B precursor
101112600 PDGFC; platelet-derived growth factor C isoform X4
101117784 PDGFD; platelet-derived growth factor D isoform X3
101106508 TGFA; protransforming growth factor alpha isoform X2
443318 IGF1; insulin-like growth factor I precursor
101108266 INSRR; insulin receptor-related protein isoform X2
101106012 PDGFRA; platelet-derived growth factor receptor alpha
101122783 PDGFRB; platelet-derived growth factor receptor beta isoform X1
780507 FGFR1; fibroblast growth factor receptor 1 isoform X2
443548 FGFR2; fibroblast growth factor receptor 2 isoform X3
780479 EGFR; epidermal growth factor receptor isoform X1
780519 ERBB2; receptor tyrosine-protein kinase erbB-2 isoform X2
443515 IGF1R; insulin-like growth factor 1 receptor
101109759 PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
101110015 PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
101117348 PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X3
101111546 PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta isoform X2
101121455 PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X3
101123247 PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1
101119351 PTEN; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X2
101117211 PDPK1; 3-phosphoinositide-dependent protein kinase 1 isoform X1
101113199 NKX3-1; homeobox protein Nkx-3.1
100294652 AKT1; RAC-alpha serine/threonine-protein kinase
101118462 AKT3; RAC-gamma serine/threonine-protein kinase isoform X2
101119242 AKT2; RAC-beta serine/threonine-protein kinase
101110953 CASP9; caspase-9 isoform X2
780444 BAD; bcl2-associated agonist of cell death
101107877 FOXO1; forkhead box protein O1
100302083 CDKN1A; cyclin-dependent kinase inhibitor 1
101103187 E3 ubiquitin-protein ligase Mdm2-like
101104979 MDM2; E3 ubiquitin-protein ligase Mdm2 isoform X1
443421 TP53; cellular tumor antigen p53
100169938 GSK3B; glycogen synthase kinase-3 beta
443118 CREB1; cyclic AMP-responsive element-binding protein 1 isoform X1
100216465 ATF4; cyclic AMP-dependent transcription factor ATF-4
101107485 CREB3L4; cyclic AMP-responsive element-binding protein 3-like protein 4 isoform X2
101108743 CREB3L2; cyclic AMP-responsive element-binding protein 3-like protein 2
101113586 CREB3L3; cyclic AMP-responsive element-binding protein 3-like protein 3 isoform X1
101113882 CREB3L1; cyclic AMP-responsive element-binding protein 3-like protein 1
101114243 CREB3; cyclic AMP-responsive element-binding protein 3
101112976 CREB5; cyclic AMP-responsive element-binding protein 5 isoform X2
100294600 CTNNB1; catenin beta-1
101110136 EP300; histone acetyltransferase p300 isoform X1
101123600 CREBBP; CREB-binding protein
101101980 TCF7; transcription factor 7 isoform X6
100913162 TCF7L1; transcription factor 7-like 1 isoform X1
101118068 TCF7L2; transcription factor 7-like 2 isoform X19
780521 LEF1; lymphoid enhancer-binding factor 1 isoform X8
100144763 CCND1; G1/S-specific cyclin-D1
101111143 CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1
780484 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X2
101107332 IKBKG; NF-kappa-B essential modulator isoform X3
780520 NFKBIA; NF-kappa-B inhibitor alpha
101108228 NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X2
101102191 RELA; transcription factor p65
101119602 BCL2; apoptosis regulator Bcl-2 isoform X1
100271659 MTOR; serine/threonine-protein kinase mTOR
101109893 GRB2; growth factor receptor-bound protein 2 isoform X5
114110058 growth factor receptor-bound protein 2
101102732 SOS2; son of sevenless homolog 2 isoform X1
101118865 SOS1; son of sevenless homolog 1 isoform X2
101104357 HRAS; GTPase HRas isoform X1
114114919 GTPase HRas-like
101114005 KRAS; GTPase KRas isoform X1
101102438 NRAS; GTPase NRas
100305131 ARAF; serine/threonine-protein kinase A-Raf
101107438 BRAF; serine/threonine-protein kinase B-raf isoform X3
101103190 RAF1; RAF proto-oncogene serine/threonine-protein kinase
101123635 MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 isoform X2
101113846 MAP2K2; dual specificity mitogen-activated protein kinase kinase 2 isoform X1
101115485 MAPK1; mitogen-activated protein kinase 1 isoform X2
101123008 MAPK3; mitogen-activated protein kinase 3
101121723 FOLH1; glutamate carboxypeptidase 2 isoform X2
443101 GRM1; metabotropic glutamate receptor 1 isoform X1
443069 GRM5; metabotropic glutamate receptor 5 isoform X1
101120775 FOLR3; folate receptor alpha
101121452 FOLR2; folate receptor beta
101119738 SLC46A1; proton-coupled folate transporter
101110110 SLC19A1; reduced folate transporter isoform X2
100820756 SRD5A2; 3-oxo-5-alpha-steroid 4-dehydrogenase 2 isoform X2
443042 AR; androgen receptor
100127209 HSP90AA1; heat shock protein HSP 90-alpha isoform X2
101117797 HSP90AB1; heat shock protein HSP 90-beta
101111703 HSP90B1; endoplasmin isoform X2
|
K23790 GSTP; glutathione S-transferase P [EC:2.5.1.18]
K23790 GSTP; glutathione S-transferase P [EC:2.5.1.18]
K06624 CDKN1B; cyclin-dependent kinase inhibitor 1B
K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
K06626 CCNE; G1/S-specific cyclin-E1
K06626 CCNE; G1/S-specific cyclin-E1
K06618 RB1; retinoblastoma-associated protein
K17454 E2F1; transcription factor E2F1
K09389 E2F2; transcription factor E2F2
K06620 E2F3; transcription factor E2F3
K09633 TMPRSS2; transmembrane protease serine 2 [EC:3.4.21.122]
K09435 ERG; transcriptional regulator ERG
K01348 PLAU; urokinase plasminogen activator [EC:3.4.21.73]
K01343 PLAT; tissue plasminogen activator [EC:3.4.21.68]
K01394 MMP3; matrix metalloproteinase-3 (stromelysin 1, progelatinase) [EC:3.4.24.17]
K01403 MMP9; matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35]
K09299 ZEB1; zinc finger homeobox protein 1
K04387 IL1R2; interleukin 1 receptor type II
K15619 SPINT1; Kunitz-type protease inhibitor 1
K15593 ETV5; ets translocation variant 5
K04526 INS; insulin
K04359 PDGFA; platelet-derived growth factor subunit A
K17386 PDGFB; platelet-derived growth factor subunit B
K05450 PDGFC_D; platelet derived growth factor C/D
K05450 PDGFC_D; platelet derived growth factor C/D
K08774 TGFA; transforming growth factor, alpha
K05459 IGF1; insulin-like growth factor 1
K05086 INSRR; insulin receptor-related receptor [EC:2.7.10.1]
K04363 PDGFRA; platelet-derived growth factor receptor alpha [EC:2.7.10.1]
K05089 PDGFRB; platelet-derived growth factor receptor beta [EC:2.7.10.1]
K04362 FGFR1; fibroblast growth factor receptor 1 [EC:2.7.10.1]
K05093 FGFR2; fibroblast growth factor receptor 2 [EC:2.7.10.1]
K04361 EGFR; epidermal growth factor receptor [EC:2.7.10.1]
K05083 ERBB2; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
K05087 IGF1R; insulin-like growth factor 1 receptor [EC:2.7.10.1]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K00922 PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K02649 PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
K01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
K09348 NKX3-1; homeobox protein Nkx-3.1
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04456 AKT; RAC serine/threonine-protein kinase [EC:2.7.11.1]
K04399 CASP9; caspase 9 [EC:3.4.22.62]
K02158 BAD; Bcl-2-antagonist of cell death
K07201 FOXO1; forkhead box protein O1
K06625 CDKN1A; cyclin-dependent kinase inhibitor 1A
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]
K04451 TP53; tumor protein p53
K03083 GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]
K05870 CREB1; cyclic AMP-responsive element-binding protein 1
K04374 ATF4; cyclic AMP-dependent transcription factor ATF-4
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09048 CREB3; cyclic AMP-responsive element-binding protein 3
K09047 CREB5; cyclic AMP-responsive element-binding protein 5
K02105 CTNNB1; catenin beta 1
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
K02620 TCF7; transcription factor 7
K04490 TCF7L1; transcription factor 7-like 1
K04491 TCF7L2; transcription factor 7-like 2
K04492 LEF1; lymphoid enhancer-binding factor 1
K04503 CCND1; G1/S-specific cyclin-D1
K04467 IKBKA; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
K07209 IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
K07210 IKBKG; inhibitor of nuclear factor kappa-B kinase subunit gamma
K04734 NFKBIA; NF-kappa-B inhibitor alpha
K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04735 RELA; transcription factor p65
K02161 BCL2; apoptosis regulator Bcl-2
K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
K04364 GRB2; growth factor receptor-bound protein 2
K04364 GRB2; growth factor receptor-bound protein 2
K03099 SOS; son of sevenless
K03099 SOS; son of sevenless
K02833 HRAS; GTPase HRas
K02833 HRAS; GTPase HRas
K07827 KRAS; GTPase KRas
K07828 NRAS; GTPase NRas
K08845 ARAF; A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04365 BRAF; B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04366 RAF1; RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
K04368 MAP2K1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
K04369 MAP2K2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K04371 ERK; mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
K14592 FOLH1; glutamate carboxypeptidase II (folate hydrolase 1) [EC:3.4.17.21]
K04603 GRM1; metabotropic glutamate receptor 1
K04604 GRM5; metabotropic glutamate receptor 5
K13649 FOLR; folate receptor
K13649 FOLR; folate receptor
K14613 SLC46A1; MFS transporter, PCFT/HCP family, solute carrier family 46 (folate transporter), member 1
K14609 SLC19A1; solute carrier family 19 (folate transporter), member 1
K12344 SRD5A2; 3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:1.3.1.22]
K08557 AR; androgen receptor
K04079 HSP90A; molecular chaperone HtpG
K04079 HSP90A; molecular chaperone HtpG
K09487 HSP90B; heat shock protein 90kDa beta
|
05213 Endometrial cancer [PATH:oas05213]
|
05224 Breast cancer [PATH:oas05224]
|
05222 Small cell lung cancer [PATH:oas05222]
|
05223 Non-small cell lung cancer [PATH:oas05223]
|
|
|
09172 Infectious disease: viral
|
|
|
09171 Infectious disease: bacterial
|
|
|
09174 Infectious disease: parasitic
|
|
|
09163 Immune disease
|
|
|
09164 Neurodegenerative disease
|
|
|
09165 Substance dependence
|
|
|
09166 Cardiovascular disease
|
|
|
09167 Endocrine and metabolic disease
|
|
|
09175 Drug resistance: antimicrobial
|
|
|
09176 Drug resistance: antineoplastic
|
|
|
09180 Brite Hierarchies
|
|
|
09190 Not Included in Pathway or Brite
|