KEGG   PATHWAY: dre04810
Entry
dre04810                    Pathway                                
Name
Regulation of actin cytoskeleton - Danio rerio (zebrafish)
Class
Cellular Processes; Cell motility
Pathway map
dre04810  Regulation of actin cytoskeleton
dre04810

Other DBs
GO: 0030036
Organism
Danio rerio (zebrafish) [GN:dre]
Gene
100000160  fgfr4; fibroblast growth factor receptor 4 precursor [KO:K05095] [EC:2.7.10.1]
100000252  pik3r3b; phosphoinositide-3-kinase, regulatory subunit 3b (gamma) [KO:K02649]
100001221  wasf1; actin-binding protein WASF1 isoform X1 [KO:K05753]
100001836  itgb3b; integrin beta-3b precursor [KO:K06493]
100002225  map2k2b; dual specificity mitogen-activated protein kinase kinase 2b [KO:K04369] [EC:2.7.12.2]
100002263  pik3cb; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
100002872  cyfip2; cytoplasmic FMR1-interacting protein 2 [KO:K05749]
100002928  iqgap1; ras GTPase-activating-like protein IQGAP1 isoform X1 [KO:K16848]
100003223  ppp1cb; serine/threonine-protein phosphatase PP1-beta catalytic subunit [KO:K06269] [EC:3.1.3.16]
100003770  mylk5; myosin light chain kinase, smooth muscle isoform X3 [KO:K00907] [EC:2.7.11.18]
100004299  arhgap35a; rho GTPase-activating protein 35 [KO:K05732]
100004742  chrm4b; muscarinic acetylcholine receptor M4 [KO:K04132]
100004938  si:dkey-63b1.1; B2 bradykinin receptor [KO:K03916]
100005033  pip5k1cb; phosphatidylinositol-4-phosphate 5-kinase, type I, gamma B [KO:K00889] [EC:2.7.1.68]
100005049  fgf1b; fibroblast growth factor 1b [KO:K18496]
100005469  fn1a; fibronectin 1a precursor [KO:K05717]
100005852  fgf22; fibroblast growth factor 22 precursor [KO:K04358]
100005903  si:dkey-27i16.2; regulator of cell cycle RGCC-like [KO:K26108]
100006041  rhoab; rho-related GTP-binding protein RhoA-B isoform X1 [KO:K04513]
100006255  itga7; integrin alpha-7 isoform X1 [KO:K06583]
100009637  wasla; WASP like actin nucleation promoting factor A [KO:K23612]
100038776  actr3b; actin-related protein 3B [KO:K18584]
100124597  f2r2.1; coagulation factor II thrombin receptor 2.1 precursor [KO:K03914]
100141346  itga8; integrin alpha-8 [KO:K06584]
100149598  chrm3b; muscarinic acetylcholine receptor M3 [KO:K04131]
100149794  akt3b; RAC-gamma serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
100150701  chrm4a; muscarinic acetylcholine receptor M4 [KO:K04132]
100151255  itgav; integrin alpha-V precursor [KO:K06487]
100317924  mrasb; ras-related protein M-Ras [KO:K07831]
100329779  rock1; rho-associated protein kinase 1 [KO:K04514] [EC:2.7.11.39]
100330358  tiam1b; rho guanine nucleotide exchange factor TIAM1 isoform X1 [KO:K05731]
100330960  bdkrb2; B2 bradykinin receptor [KO:K03916]
100331333  itga4; integrin alpha-4 isoform X1 [KO:K06483]
100331581  gng12b; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 [KO:K04347]
100331874  itga3b; integrin alpha-3b precursor [KO:K06482]
100333179  vav3; guanine nucleotide exchange factor VAV3 isoform X1 [KO:K05730]
100334859  vclB; vinculin B [KO:K05700]
100499533  itgb6; integrin beta-6 isoform X1 [KO:K06589]
100534937  [KO:K04526]
100535634  pip4k2cb; phosphatidylinositol 5-phosphate 4-kinase type-2 gamma isoform X1 [KO:K00920] [EC:2.7.1.149]
100535718  pdgfd; platelet-derived growth factor D isoform X2 [KO:K05450]
100536197  pak6; serine/threonine-protein kinase PAK 6 [KO:K05735] [EC:2.7.11.1]
100536317  mrasa; ras-related protein M-Ras isoform X1 [KO:K07831]
100536533  itga2.2; integrin alpha-2 [KO:K06481]
100536705  itgae.2; integrin alpha-E [KO:K06524]
100537012  baiap2b; BAR/IMD domain-containing adapter protein 2 isoform X16 [KO:K05627]
100537244  myl2a; myosin regulatory light chain 2a [KO:K10351]
100537765  [KO:K04392]
100537977  iqgap3; ras GTPase-activating-like protein IQGAP3 [KO:K05767]
101882228  diaph1; protein diaphanous homolog 1 isoform X1 [KO:K05740]
101882585  itgam.1; integrin alpha-M isoform X1 [KO:K06461]
101883214  limk1b; LIM domain kinase 1 [KO:K05743] [EC:2.7.11.1]
101884366  [KO:K04361] [EC:2.7.10.1]
101885659  ssh1a; protein phosphatase Slingshot homolog 1 isoform X1 [KO:K05766] [EC:3.1.3.16 3.1.3.48]
101885761  slc9a1a; sodium/hydrogen exchanger 1 [KO:K05742]
101885790  ppp1r12b; protein phosphatase 1 regulatory subunit 12B isoform X8 [KO:K12329]
101886694  [KO:K05766] [EC:3.1.3.16 3.1.3.48]
101910198  akt1; RAC-alpha serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
114447  cxcr4b; C-X-C chemokine receptor type 4b [KO:K04189]
114456  arpc4; actin-related protein 2/3 complex subunit 4 [KO:K05755]
137494316  [KO:K05730]
140747  cxcr4a; C-X-C chemokine receptor type 4a [KO:K04189]
141376742  [KO:K06461]
141379850  [KO:K03996]
142986  ptk2ab; focal adhesion kinase 1 [KO:K05725] [EC:2.7.10.2]
266749  pak2a; serine/threonine-protein kinase PAK 2a [KO:K04410] [EC:2.7.11.1]
286739  msnA; moesin A [KO:K05763]
30262  ins; insulin preproprotein [KO:K04526]
30380  nraS; GTPase NRas [KO:K07828]
30429  mylpfa; myosin regulatory light chain 2, skeletal muscle isoform A [KO:K12758]
30538  fgf8a; fibroblast growth factor 8 precursor [KO:K04358]
30549  fgf3; fibroblast growth factor 3 precursor [KO:K04358]
30560  fgf6a; fibroblast growth factor 6a precursor [KO:K04358]
30592  myl7; myosin regulatory light chain 2, atrial isoform [KO:K12754]
30705  fgfr1a; fibroblast growth factor receptor 1-A isoform 1 precursor [KO:K04362] [EC:2.7.10.1]
30716  raf1a; Raf-1 proto-oncogene, serine/threonine kinase A [KO:K04366] [EC:2.7.11.1]
317747  rock2a; rho-associated protein kinase 2 [KO:K17388] [EC:2.7.11.39]
321070  rock2b; rho-associated protein kinase 2b [KO:K17388] [EC:2.7.11.39]
321099  gsnA; gelsolin A [KO:K05768]
321383  pfn2a; profilin 2a [KO:K05759]
321496  cfl1; cofilin-1 [KO:K05765]
322221  actn4; alpha-actinin-4 [KO:K05699]
323285  scinla; scinderin like A [KO:K05768]
325034  pak2b; serine/threonine-protein kinase PAK 2b [KO:K04410] [EC:2.7.11.1]
325084  src; proto-oncogene tyrosine-protein kinase Src [KO:K05704] [EC:2.7.10.2]
325085  ssh2a; protein phosphatase Slingshot homolog 2 isoform X2 [KO:K05766] [EC:3.1.3.16 3.1.3.48]
325881  f2; prothrombin precursor [KO:K01313] [EC:3.4.21.5]
326719  myl12.1; myosin, light chain 12, genome duplicate 1 [KO:K12757]
326825  gna13a; guanine nucleotide-binding protein subunit alpha-13a [KO:K04639]
327068  arpc2; actin-related protein 2/3 complex subunit 2 [KO:K05758]
327204  rac1a; ras-related C3 botulinum toxin substrate 1 [KO:K04392]
327301  ppp1cab; protein phosphatase 1, catalytic subunit, alpha isozyme B [KO:K06269] [EC:3.1.3.16]
333938  myh9a; myosin-9a isoform X1 [KO:K10352]
334597  ppp1cbl; protein phosphatase 1, catalytic subunit, beta isoform, like [KO:K06269] [EC:3.1.3.16]
335269  itgb4; integrin beta-4 isoform X1 [KO:K06525]
335474  arpc1b; actin-related protein 2/3 complex subunit 1B [KO:K05757]
336333  gna13b; guanine nucleotide-binding protein subunit alpha-13b [KO:K04639]
336504  arpc5a; actin-related protein 2/3 complex subunit 5a [KO:K05754]
336613  cyfip1; cytoplasmic FMR1-interacting protein 1 homolog [KO:K05749]
336623  gsnB; gelsolin B [KO:K05768]
336839  cdc42; cell division control protein 42 homolog isoform 2 [KO:K04393]
337084  myl12.2; myosin, light chain 12, genome duplicate 2 [KO:K12757]
337690  [KO:K00921] [EC:2.7.1.150]
352938  chrm2a; muscarinic acetylcholine receptor M2a [KO:K04130]
352940  fgfr2; fibroblast growth factor receptor 2 isoform 1 precursor [KO:K05093] [EC:2.7.10.1]
352944  cxcl12a; chemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1) precursor [KO:K10031]
359829  fgf18a; fibroblast growth factor 18a precursor [KO:K04358]
359830  fgf10a; fibroblast growth factor 10a precursor [KO:K04358]
359831  fgf24; fibroblast growth factor 24 precursor [KO:K04358]
360144  mapk1; mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
368199  bdkrb1; B1 bradykinin receptor [KO:K03916]
368245  fgf19; fibroblast growth factor 19 isoform 1 [KO:K22603]
368461  lpar1; lysophosphatidic acid receptor 1 isoform X1 [KO:K04289]
373103  pak1; serine/threonine-protein kinase PAK 1 isoform X1 [KO:K04409] [EC:2.7.11.1]
373124  pip4k2ca; phosphatidylinositol 5-phosphate 4-kinase type-2 gamma [KO:K00920] [EC:2.7.1.149]
378478  egfra; epidermal growth factor receptor precursor [KO:K04361] [EC:2.7.10.1]
378480  pdgfaa; platelet-derived growth factor alpha polypeptide a precursor [KO:K04359]
378872  fam49a; uncharacterized protein LOC378872 isoform 2 [KO:K27976]
378972  akt2; RAC-beta serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
386705  ptk2aa; protein tyrosine kinase 2aa [KO:K05725] [EC:2.7.10.2]
386762  apc; adenomatous polyposis coli protein [KO:K02085]
386787  itga5; integrin alpha-5 precursor [KO:K06484]
386856  pdgfra; platelet-derived growth factor receptor alpha precursor [KO:K04363] [EC:2.7.10.1]
393228  zgc:55558; GTPase KRas isoform X1 [KO:K07827]
393550  arpc5la; actin related protein 2/3 complex, subunit 5-like, A [KO:K05754]
393611  c6.2; complement component C6 precursor [KO:K03995]
393733  fgf1a; putative fibroblast growth factor 1 [KO:K18496]
393837  c8g; complement component C8 gamma chain precursor [KO:K03999]
394012  itga9; integrin alpha-9 [KO:K06585]
394034  waslb; WASP like actin nucleation promoting factor B [KO:K23612]
394056  wasf2; actin-binding protein WASF2 [KO:K05748]
394125  rhoca; ras homolog family member Ca [KO:K04513]
394174  pik3cd; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform [KO:K00922] [EC:2.7.1.153]
394235  pfn2b; profilin-2 [KO:K05759]
394243  arpc1a; actin-related protein 2/3 complex subunit 1A [KO:K05757]
399480  mapk3; mitogen-activated protein kinase 3 isoform X1 [KO:K04371] [EC:2.7.11.24]
399482  arpc5b; actin-related protein 2/3 complex subunit 5b [KO:K05754]
399546  pxnA; paxillin A [KO:K05760]
402820  tmsB; thymosin beta [KO:K05764]
403001  cfl2; cofilin-2 [KO:K05765]
403009  ezrA; ezrin A [KO:K08007]
403045  egf; pro-epidermal growth factor isoform 1 precursor [KO:K04357]
403063  araF; serine/threonine-protein kinase A-Raf [KO:K08845] [EC:2.7.11.1]
403065  braF; serine/threonine-protein kinase B-raf isoform 1 [KO:K04365] [EC:2.7.11.1]
403146  akt2l; v-akt murine thymoma viral oncogene homolog 2, like isoform X1 [KO:K04456] [EC:2.7.11.1]
404211  pik3r2; phosphatidylinositol 3-kinase regulatory subunit beta isoform X1 [KO:K02649]
404231  fgf2; fibroblast growth factor 2 [KO:K18497]
404610  fam49bb; CYFIP-related Rac1 interactor B [KO:K27976]
405898  pak5; serine/threonine-protein kinase PAK 5 isoform X1 [KO:K05736] [EC:2.7.11.1]
406250  actr3; actin-related protein 3 [KO:K18584]
406363  scinlb; scinderin like B [KO:K05768]
406411  rhoaa; rho-related GTP-binding protein RhoA-A [KO:K04513]
406493  myl9b; myosin regulatory light polypeptide 9b [KO:K12755]
406604  gng12a; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12a isoform X1 [KO:K04347]
406659  rhoac; rho-related GTP-binding protein RhoA-C [KO:K04513]
406728  map2k1; dual specificity mitogen-activated protein kinase kinase 1 [KO:K04368] [EC:2.7.12.2]
406738  cfl1l; non-muscle cofilin 1-like [KO:K05765]
406820  actr2a; actin-related protein 2-A [KO:K17260]
407685  itga3a; integrin alpha-3 isoform X1 [KO:K06482]
407737  fgf17; fibroblast growth factor 17 precursor [KO:K04358]
407980  ppp1caa; protein phosphatase 1, catalytic subunit, alpha isozyme A [KO:K06269] [EC:3.1.3.16]
415151  rac2; ras-related C3 botulinum toxin substrate 2 [KO:K07860]
415187  brk1; probable protein BRICK1 [KO:K05752]
415190  zgc:86896; uncharacterized protein LOC415190 [KO:K05757]
415204  arpc3; actin-related protein 2/3 complex subunit 3 [KO:K05756]
431737  rgcC; regulator of cell cycle RGCC [KO:K26108]
431769  pak4; serine/threonine-protein kinase PAK 4 [KO:K05734] [EC:2.7.11.1]
436718  rhocb; rho-related GTP-binding protein RhoA-D [KO:K04513]
436924  limk2; LIM domain kinase 2 [KO:K05744] [EC:2.7.11.1]
437027  rac3a; ras-related C3 botulinum toxin substrate 3a [KO:K07861]
445102  c8a; complement component C8 alpha chain [KO:K03997]
445184  lpar2a; lysophosphatidic acid receptor 2a [KO:K04291]
445212  fam49al; uncharacterized protein isoform X2 [KO:K27976]
445234  crk; adapter molecule crk [KO:K04438]
445289  kraS; GTPase KRas isoform 2 [KO:K07827]
445305  arpc4l; actin related protein 2/3 complex, subunit 4, like [KO:K05755]
445380  itga2b; integrin alpha-IIb precursor [KO:K06476]
445393  ppp1r12a; protein phosphatase 1 regulatory subunit 12A [KO:K06270]
447840  pip5k1bb; phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X1 [KO:K00889] [EC:2.7.1.68]
447930  mylpfb; myosin regulatory light chain 2, skeletal muscle isoform B [KO:K12758]
449660  rraS; ras-related protein R-Ras [KO:K07830]
449707  mylk4b; myosin light chain kinase family member 4 isoform X4 [KO:K00907] [EC:2.7.11.18]
449808  kng1; kininogen-1 precursor [KO:K03898]
449831  pip5k1ba; phosphatidylinositol-4-phosphate 5-kinase, type I, beta a isoform X2 [KO:K00889] [EC:2.7.1.68]
450006  myl9a; uncharacterized protein isoform X1 [KO:K12755]
492549  pip5k1ab; phosphatidylinositol 4-phosphate 5-kinase type-1 alpha [KO:K00889] [EC:2.7.1.68]
492576  mylkb; myosin light chain kinase, smooth muscle [KO:K00907] [EC:2.7.11.18]
493181  fgf7; fibroblast growth factor 7 isoform X1 [KO:K04358]
493612  zgc:101810; uncharacterized protein LOC493612 [KO:K17260]
494081  arhgef7b; rho guanine nucleotide exchange factor 7b [KO:K13710]
494454  fgf5; fibroblast growth factor 5 precursor [KO:K04358]
494455  fgf6b; fibroblast growth factor 6b precursor [KO:K04358]
494456  fgf23; fibroblast growth factor 23 precursor [KO:K22428]
497639  fgf18b; fibroblast growth factor 18b precursor [KO:K04358]
503589  gna12a; guanine nucleotide-binding protein subunit alpha-12a [KO:K04346]
503893  itga6a; integrin alpha-6 isoform X1 [KO:K06485]
541320  itga6b; integrin alpha-6b precursor [KO:K06485]
541394  enaH; protein enabled homolog isoform 1 [KO:K05746]
541475  itga11a; integrin alpha-11a precursor [KO:K06587]
550286  hrasa; HRas proto-oncogene, GTPase A [KO:K02833]
550513  rras2; ras-related protein R-Ras2 [KO:K07830]
550569  myl10; myosin regulatory light chain 10 [KO:K12756]
552980  vclA; vinculin A [KO:K05700]
553434  msnB; moesin B [KO:K05763]
553493  arhgef7a; rho guanine nucleotide exchange factor 7a [KO:K13710]
553629  pip5k1aa; phosphatidylinositol-4-phosphate 5-kinase, type I, alpha, A [KO:K00889] [EC:2.7.1.68]
553656  hrasb; HRas proto-oncogene, GTPase B [KO:K02833]
553978  chrm5a; muscarinic acetylcholine receptor M5a isoform X1 [KO:K04133]
554141  c9; complement component C9 precursor [KO:K04000]
554168  myh11a; myosin-11a [KO:K10352]
554861  actr2b; actin-related protein 2-B isoform X2 [KO:K17260]
555254  itga6l; integrin alpha-6 isoform X1 [KO:K06485]
555454  myh10; myosin-10 isoform X1 [KO:K10352]
555516  chrm2b; muscarinic acetylcholine receptor M2 [KO:K04130]
555920  pip4k2ab; phosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform X1 [KO:K00920] [EC:2.7.1.149]
556029  diaph2; protein diaphanous homolog 2 isoform X1 [KO:K05741]
556104  arpc5lb; actin related protein 2/3 complex, subunit 5-like, B [KO:K05754]
556226  cdc42l2; cell division cycle 42 like 2 isoform X1 [KO:K04393]
556286  sos1; son of sevenless homolog 1 [KO:K03099]
556413  vav2; guanine nucleotide exchange factor VAV2 isoform X2 [KO:K05730]
556443  crkL; crk-like protein [KO:K04438]
556734  itgb1a; integrin beta-1a isoform X1 [KO:K05719]
556752  itgb8; integrin beta-8 isoform X1 [KO:K06591]
556873  pfn4; profilin-4 [KO:K05759]
556951  nckap1l; nck-associated protein 1-like [KO:K05750]
557109  raf1b; RAF proto-oncogene serine/threonine-protein kinase isoform X1 [KO:K04366] [EC:2.7.11.1]
557176  pik3r1; phosphatidylinositol 3-kinase regulatory subunit alpha [KO:K02649]
557797  itgb2; integrin beta-2 [KO:K06464]
557912  ssh2b; protein phosphatase Slingshot homolog 2b [KO:K05766] [EC:3.1.3.16 3.1.3.48]
557935  zmp:0000001082; integrin alpha-D isoform 1 precursor [KO:K05718]
557983  arhgef1; rho guanine nucleotide exchange factor 1 [KO:K12330]
558288  arhgef6; rho guanine nucleotide exchange factor 6 isoform X2 [KO:K05729]
558477  f2r; proteinase-activated receptor 1 precursor [KO:K03914]
558685  mylk2; myosin light chain kinase 2, skeletal/cardiac muscle [KO:K00907] [EC:2.7.11.18]
559145  vav3b; guanine nucleotide exchange factor VAV3b [KO:K05730]
559529  pdgfrb; platelet-derived growth factor receptor beta precursor [KO:K05089] [EC:2.7.10.1]
559630  fgf20a; fibroblast growth factor 20a [KO:K04358]
560305  fgd1; FYVE, RhoGEF and PH domain-containing protein 1 isoform X2 [KO:K05720]
560360  pip4k2aa; phosphatidylinositol 5-phosphate 4-kinase type-2 alpha [KO:K00920] [EC:2.7.1.149]
560400  actn1; alpha-actinin-1 [KO:K05699]
560549  akt3a; RAC-gamma serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
560564  pdgfc; platelet-derived growth factor C isoform X2 [KO:K05450]
561431  myh9b; myosin-9 isoform X1 [KO:K10352]
561491  chrm5b; muscarinic acetylcholine receptor M5b [KO:K04133]
561589  ezrB; ezrin b isoform X1 [KO:K08007]
561635  mylk3; myosin light chain kinase 3 [KO:K00907] [EC:2.7.11.18]
561670  sos2; son of sevenless homolog 2 [KO:K03099]
561737  pik3ca; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
561894  nckap1; nck-associated protein 1 [KO:K05750]
562455  arhgef12a; rho guanine nucleotide exchange factor 12 isoform X1 [KO:K07532]
562475  c7a; complement component C7 isoform X2 [KO:K03996]
562838  rac1b; ras-related C3 botulinum toxin substrate 1b [KO:K04392]
563030  iqgap2; ras GTPase-activating-like protein IQGAP2 [KO:K05767]
563181  map2k2a; dual specificity mitogen-activated protein kinase kinase 2a [KO:K04369] [EC:2.7.12.2]
563556  itgb5; integrin beta-5 precursor [KO:K06588]
564266  itgb3a; integrin beta-3a precursor [KO:K06493]
564565  arhgap35b; rho GTPase-activating protein 35 [KO:K05732]
564770  fgf20b; fibroblast growth factor 20b [KO:K04358]
565130  pxnB; paxillin isoform X10 [KO:K05760]
565771  apc2; adenomatous polyposis coli protein 2 [KO:K02085]
565774  c5; complement C5 [KO:K03994]
566329  tmsb2; thymosin beta [KO:K05764]
566735  insB; preproinsulin b precursor [KO:K04526]
566764  sciN; scinderin [KO:K05768]
566845  mylk4a; uncharacterized protein mylk4a isoform X2 [KO:K00907] [EC:2.7.11.18]
567175  itga11b; integrin alpha-11 isoform X2 [KO:K06587]
567479  ssh1b; protein phosphatase Slingshot homolog 1 isoform X1 [KO:K05766] [EC:3.1.3.16 3.1.3.48]
567621  tiam1a; rho guanine nucleotide exchange factor TIAM1 isoform X1 [KO:K05731]
567874  pak6b; serine/threonine-protein kinase PAK 6b [KO:K05735] [EC:2.7.11.1]
567905  fgfr1b; fibroblast growth factor receptor 1b precursor [KO:K04362] [EC:2.7.10.1]
567956  lpar2b; lysophosphatidic acid receptor 2b isoform X2 [KO:K04291]
568309  bcar1; breast cancer anti-estrogen resistance protein 1 [KO:K05726]
568426  spata13; spermatogenesis-associated protein 13 isoform X1 [KO:K05769]
568935  git1; ARF GTPase-activating protein GIT1 isoform X2 [KO:K05737]
569510  mylka; myosin light chain kinase, smooth muscle isoform X1 [KO:K00907] [EC:2.7.11.18]
569566  fgfr1bl; fibroblast growth factor receptor 1 [KO:K04362] [EC:2.7.10.1]
570216  itgb1b; integrin beta-1b precursor [KO:K05719]
570218  ppp1r12c; protein phosphatase 1 regulatory subunit 12C [KO:K17457]
570435  fgf4; fibroblast growth factor 4 precursor [KO:K04358]
570832  c7b; complement component 7b precursor [KO:K03996]
570868  itga1; integrin alpha-1 isoform X1 [KO:K06480]
571031  arhgef12b; rho guanine nucleotide exchange factor 12 isoform X1 [KO:K07532]
571431  [KO:K04361] [EC:2.7.10.1]
571679  chrm3a; muscarinic acetylcholine receptor M3 [KO:K04131]
571753  ppp1cc; serine/threonine-protein phosphatase PP1-gamma catalytic subunit A [KO:K06269] [EC:3.1.3.16]
571837  zmp:0000001167; protein phosphatase 1 regulatory subunit 12A isoform X1 [KO:K06270]
572187  dock1; dedicator of cytokinesis protein 1 [KO:K13708]
572348  itga10; integrin alpha-10 [KO:K06586]
57934  actb1; actin, cytoplasmic 1 [KO:K05692]
57935  actb2; actin, cytoplasmic 2 [KO:K05692]
58075  fgd; faciogenital dysplasia isoform X1 [KO:K05722]
58129  fgfr3; fibroblast growth factor receptor 3 precursor [KO:K05094] [EC:2.7.10.1]
65089  fgf8b; fibroblast growth factor 8b precursor [KO:K04358]
677750  myl2b; myosin, light chain 2b, regulatory, cardiac, slow [KO:K10351]
678518  baiap2a; brain-specific angiogenesis inhibitor 1-associated protein 2A [KO:K05627]
692065  fgf16; fibroblast growth factor 16 [KO:K04358]
692331  abi2b; abl interactor 2b [KO:K05751]
724048  fgf21; fibroblast growth factor 21 [KO:K22429]
735292  limk1a; LIM domain kinase 1a [KO:K05743] [EC:2.7.11.1]
751630  zgc:153713; RhoA_like domain-containing protein [KO:K04513]
751792  fgf10b; fibroblast growth factor 10b precursor [KO:K04358]
767646  abi2a; abl interactor 2a [KO:K05751]
767790  pdgfab; platelet-derived growth factor alpha polypeptide b precursor [KO:K04359]
791141  zgc:158659; uncharacterized protein isoform X1 [KO:K00922] [EC:2.7.1.153]
791177  zgc:158689; uncharacterized protein LOC791177 [KO:K05627]
792699  rac1l; ras-related C3 botulinum toxin substrate 1 [KO:K04392]
792708  chrm1a; muscarinic acetylcholine receptor M1 [KO:K04129]
793127  c8b; complement component C8 beta chain precursor [KO:K03998]
793158  cdc42l; cell division cycle 42, like [KO:K04393]
793949  tmsb4x; thymosin beta-4 [KO:K05764]
794278  [KO:K03914]
794365  f2r2.2; proteinase-activated receptor 1-like [KO:K03914]
794658  chrm1b; muscarinic acetylcholine receptor M3 [KO:K04129]
794698  lpar4; lysophosphatidic acid receptor 4 [KO:K04275]
795135  slc9a1b; sodium/hydrogen exchanger 1b precursor [KO:K05742]
795167  rac3b; ras-related C3 botulinum toxin substrate 3b [KO:K07861]
795517  mos; proto-oncogene serine/threonine-protein kinase mos [KO:K04367] [EC:2.7.11.1]
796490  pdgfbb; uncharacterized protein pdgfbb isoform X1 [KO:K04359]
797491  itgb7; integrin beta-7 isoform X1 [KO:K06590]
798657  pdgfba; platelet-derived growth factor beta polypeptide a precursor [KO:K17386]
798694  c6.1; complement component C6 isoform X1 [KO:K03995]
798876  pip5k1ca; phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform X2 [KO:K00889] [EC:2.7.1.68]
799082  [KO:K03914]
799354  cxcl12b; chemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1) precursor [KO:K10031]
799355  pfn1; profilin-1 [KO:K05759]
Compound
C00681  1-Acyl-sn-glycerol 3-phosphate
C01996  Acetylcholine
C04637  1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
Reference
PMID:14744429
  Authors
Burridge K, Wennerberg K.
  Title
Rho and Rac take center stage.
  Journal
Cell 116:167-79 (2004)
DOI:10.1016/S0092-8674(04)00003-0
Reference
PMID:11082269
  Authors
Schmitz AA, Govek EE, Bottner B, Van Aelst L.
  Title
Rho GTPases: signaling, migration, and invasion.
  Journal
Exp Cell Res 261:1-12 (2000)
DOI:10.1006/excr.2000.5049
Reference
PMID:11152757
  Authors
Takai Y, Sasaki T, Matozaki T.
  Title
Small GTP-binding proteins.
  Journal
Physiol Rev 81:153-208 (2001)
DOI:10.1152/physrev.2001.81.1.153
Reference
PMID:12700767
  Authors
Pollard TD.
  Title
The cytoskeleton, cellular motility and the reductionist agenda.
  Journal
Nature 422:741-5 (2003)
DOI:10.1038/nature01598
Reference
PMID:14657486
  Authors
Ridley AJ, Schwartz MA, Burridge K, Firtel RA, Ginsberg MH, Borisy G, Parsons JT, Horwitz AR.
  Title
Cell migration: integrating signals from front to back.
  Journal
Science 302:1704-9 (2003)
DOI:10.1126/science.1092053
Reference
PMID:11082272
  Authors
Sastry SK, Burridge K.
  Title
Focal adhesions: a nexus for intracellular signaling and cytoskeletal dynamics.
  Journal
Exp Cell Res 261:25-36 (2000)
DOI:10.1006/excr.2000.5043
Reference
PMID:10574699
  Authors
Fukata M, Nakagawa M, Kuroda S, Kaibuchi K.
  Title
Cell adhesion and Rho small GTPases.
  Journal
J Cell Sci 112 ( Pt 24):4491-500 (1999)
Related
pathway
dre04010  MAPK signaling pathway
dre04510  Focal adhesion
dre04520  Adherens junction
KO pathway
ko04810   

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