KEGG   PATHWAY: mcc04060
Entry
mcc04060                    Pathway                                
Name
Cytokine-cytokine receptor interaction - Macaca mulatta (rhesus monkey)
Description
Cytokines are soluble extracellular proteins or glycoproteins that are crucial intercellular regulators and mobilizers of cells engaged in innate as well as adaptive inflammatory host defenses, cell growth, differentiation, cell death, angiogenesis, and development and repair processes aimed at the restoration of homeostasis. Cytokines are released by various cells in the body, usually in response to an activating stimulus, and they induce responses through binding to specific receptors on the cell surface of target cells. Cytokines can be grouped by structure into different families and their receptors can likewise be grouped.
Class
Environmental Information Processing; Signaling molecules and interaction
Pathway map
mcc04060  Cytokine-cytokine receptor interaction
mcc04060

Organism
Macaca mulatta (rhesus monkey) [GN:mcc]
Gene
100423131  [KO:K05507]
100423877  IFNGR1; interferon gamma receptor 1 precursor [KO:K05132]
100423954  [KO:K05408]
100424064  [KO:K05505]
100424175  TNFRSF11A; tumor necrosis factor receptor superfamily member 11A [KO:K05147]
100426537  [KO:K05408]
100426588  IL18R1; interleukin-18 receptor 1 isoform X1 [KO:K05173]
100426632  [KO:K12964]
100427030  BMP8B; bone morphogenetic protein 8B [KO:K16622]
100428046  CCL22; C-C motif chemokine 22 [KO:K21095]
100428640  THPO; LOW QUALITY PROTEIN: thrombopoietin [KO:K06854]
100428875  IL1F10; interleukin-1 family member 10 [KO:K05488]
100430035  TNFRSF10C; LOW QUALITY PROTEIN: tumor necrosis factor receptor superfamily member 10C [KO:K22701]
100430368  CCL15; C-C motif chemokine 15 [KO:K05511]
100430627  [KO:K12964]
100551506  TNFSF12; tumor necrosis factor ligand superfamily member 12 [KO:K05474]
100551507  TNFSF13; tumor necrosis factor ligand superfamily member 13 [KO:K05475]
106992315  TGFB1; transforming growth factor beta-1 proprotein isoform X2 [KO:K13375]
106992322  [KO:K05414]
106993736  IFNE; interferon epsilon [KO:K05442]
106995138  IL3RA; interleukin-3 receptor subunit alpha isoform X1 [KO:K04737]
106995742  CRLF2; cytokine receptor-like factor 2 [KO:K05078]
106995851  IFNA6; interferon alpha-6 [KO:K05414]
106999707  [KO:K22702]
114669732  [KO:K05438]
114669819  [KO:K05438]
114669829  TNFRSF6B; tumor necrosis factor receptor superfamily member 6B [KO:K05143]
114672663  [KO:K05414]
114672664  [KO:K05414]
114673087  [KO:K05408]
114673168  [KO:K05438]
114673169  [KO:K05438]
114675335  [KO:K04388] [EC:2.7.11.30]
114675338  [KO:K05165]
114675718  [KO:K04737]
114675730  [KO:K05440]
114678790  [KO:K22672]
574098  CCR2; C-C chemokine receptor type 2 [KO:K04177]
574100  IL16; pro-interleukin-16 [KO:K22628]
574126  LEPR; leptin receptor [KO:K05062]
574127  IL6ST; interleukin-6 receptor subunit beta precursor [KO:K05060]
574138  CCL2; C-C motif chemokine 2 precursor [KO:K14624]
574151  IL18; interleukin-18 [KO:K05482]
574159  FASLG; tumor necrosis factor ligand superfamily member 6 [KO:K04389]
574160  CD40LG; CD40 ligand [KO:K03161]
574168  IL7; interleukin-7 precursor [KO:K05431]
574177  CCL1; C-C motif chemokine 1 precursor [KO:K05514]
574178  CCL5; C-C motif chemokine 5 precursor [KO:K12499]
574179  CCL8; C-C motif chemokine 8 precursor [KO:K16596]
574180  CCL17; C-C motif chemokine 17 precursor [KO:K21083]
574181  CCL18; C-C motif chemokine 18 precursor [KO:K21094]
574182  CCL20; C-C motif chemokine 20 precursor [KO:K14625]
574183  CCL21; C-C motif chemokine 21 precursor [KO:K16062]
574188  CCR1; C-C chemokine receptor type 1 [KO:K04176]
574199  IL12RB1; interleukin-12 receptor subunit beta-1 [KO:K05063]
574200  TNFRSF13B; tumor necrosis factor receptor superfamily member 13B isoform X1 [KO:K05150]
574217  CCL4L1; C-C motif chemokine 4 precursor [KO:K12964]
574218  CCL11; eotaxin precursor [KO:K16597]
574219  CCL25; C-C motif chemokine 25 precursor [KO:K13072]
574220  CCL27; C-C motif chemokine 27 precursor [KO:K16598]
574221  CCL28; C-C motif chemokine 28 precursor [KO:K05513]
574222  CXCL1; growth-regulated alpha protein precursor [KO:K05505]
574223  CXCL3; C-X-C motif chemokine 3 precursor [KO:K05505]
574224  CXCL13; C-X-C motif chemokine 13 precursor [KO:K10032]
574225  CX3CL1; fractalkine precursor [KO:K05508]
574231  CCR7; C-C chemokine receptor type 7 precursor [KO:K04182]
574243  CXCL10; C-X-C motif chemokine 10 precursor [KO:K12671]
574281  IL4; interleukin-4 precursor [KO:K05430]
574282  IFNG; interferon gamma precursor [KO:K04687]
574300  IL2RA; interleukin-2 receptor subunit alpha precursor [KO:K05068]
574304  NGFR; tumor necrosis factor receptor superfamily member 16 [KO:K02583]
574325  IL13; interleukin-13 precursor [KO:K05435]
574332  FAS; tumor necrosis factor receptor superfamily member 6 precursor [KO:K04390]
574334  CXCL12; stromal cell-derived factor 1 precursor [KO:K10031]
574335  CCR6; C-C chemokine receptor type 6 [KO:K04181]
574336  CXCL9; C-X-C motif chemokine 9 precursor [KO:K05416]
574343  INHBB; inhibin beta B chain [KO:K22687]
574366  CCL23; C-C motif chemokine 23 precursor [KO:K05511]
574367  XCL1; lymphotactin precursor [KO:K05507]
574371  CSF2; granulocyte-macrophage colony-stimulating factor precursor [KO:K05427]
574372  CXCL11; C-X-C motif chemokine 11 precursor [KO:K12672]
574379  INHA; inhibin alpha chain precursor [KO:K05500]
574386  CCL19; C-C motif chemokine 19 precursor [KO:K05512]
574387  IL1RAP; interleukin-1 receptor accessory protein precursor [KO:K04723]
613028  CXCL8; interleukin-8 precursor [KO:K10030]
619514  CCL3; C-C motif chemokine 3 precursor [KO:K05408]
641338  IL2RG; cytokine receptor common subunit gamma precursor [KO:K05070]
678654  TNFSF18; tumor necrosis factor ligand superfamily member 18 [KO:K05479]
692074  CXCR1; C-X-C chemokine receptor type 1 [KO:K04175]
693569  OSMR; oncostatin-M-specific receptor subunit beta isoform X2 [KO:K05057]
693671  IL17RB; interleukin-17 receptor B isoform X1 [KO:K05165]
693806  CCR8; C-C chemokine receptor type 8 [KO:K04183]
693917  TNFSF13B; tumor necrosis factor ligand superfamily member 13B isoform X2 [KO:K05476]
693926  CX3CR1; CX3C chemokine receptor 1 [KO:K04192]
694110  EDA; ectodysplasin-A isoform X1 [KO:K05480]
694139  LIFR; leukemia inhibitory factor receptor isoform X1 [KO:K05058]
694428  ACKR3; atypical chemokine receptor 3 [KO:K04304]
694451  TNFSF10; tumor necrosis factor ligand superfamily member 10 precursor [KO:K04721]
694541  IL24; interleukin-24 [KO:K22668]
694618  BMP4; bone morphogenetic protein 4 isoform X1 [KO:K04662]
694631  [KO:K05414]
694689  IL20; interleukin-20 [KO:K22667]
694747  IL12B; interleukin-12 subunit beta precursor [KO:K05425]
694806  IL19; LOW QUALITY PROTEIN: interleukin-19 [KO:K05444]
694931  IL10; interleukin-10 precursor [KO:K05443]
695042  TNFRSF14; tumor necrosis factor receptor superfamily member 14 precursor [KO:K05152]
695059  EDAR; tumor necrosis factor receptor superfamily member EDAR isoform X2 [KO:K05162]
695091  BMP6; bone morphogenetic protein 6 [KO:K16620]
695432  BMP3; bone morphogenetic protein 3 [KO:K05496]
695457  BMP15; bone morphogenetic protein 15 [KO:K05498]
695997  IFNL3; interferon lambda-3 [KO:K22669]
696071  ACVR2B; activin receptor type-2B isoform X1 [KO:K13596] [EC:2.7.11.30]
696117  [KO:K22669]
696331  IL2RB; interleukin-2 receptor subunit beta precursor [KO:K05069]
696471  ACVRL1; serine/threonine-protein kinase receptor R3 isoform X2 [KO:K13594] [EC:2.7.11.30]
696587  ACVR1B; activin receptor type-1B precursor [KO:K13567] [EC:2.7.11.30]
696898  BMPR1A; bone morphogenetic protein receptor type-1A precursor [KO:K04673] [EC:2.7.11.30]
696948  BMP7; bone morphogenetic protein 7 [KO:K16621]
697000  RELL1; RELT-like protein 1 precursor [KO:K26541]
697161  IFNL1; interferon lambda-1 [KO:K05447]
697508  CSF2RB; cytokine receptor common subunit beta isoform X1 [KO:K04738]
697826  ACVR1C; activin receptor type-1C precursor [KO:K13568] [EC:2.7.11.30]
697935  ACVR1; activin receptor type-1 precursor [KO:K04675] [EC:2.7.11.30]
697986  GHR; growth hormone receptor precursor [KO:K05080]
698728  LEP; leptin precursor [KO:K05424]
698961  CSF3; granulocyte colony-stimulating factor [KO:K05423]
698972  IL17RE; interleukin-17 receptor E isoform X4 [KO:K05168]
699223  IL17RC; interleukin-17 receptor C isoform X1 [KO:K05166]
699369  PRLR; prolactin receptor [KO:K05081]
699438  CXCR3; C-X-C chemokine receptor type 3 [KO:K04188]
699489  IFNGR2; interferon gamma receptor 2 [KO:K05133]
699559  TNFRSF18; tumor necrosis factor receptor superfamily member 18 [KO:K05154]
699604  IFNAR1; interferon alpha/beta receptor 1 precursor [KO:K05130]
699616  IL15; interleukin-15 precursor [KO:K05433]
699674  TNFRSF4; tumor necrosis factor receptor superfamily member 4 [KO:K05142]
699726  IFNAR2; interferon alpha/beta receptor 2 isoform X1 [KO:K05131]
699778  [KO:K16598]
699869  IL7R; interleukin-7 receptor subunit alpha [KO:K05072]
699955  TNFSF11; tumor necrosis factor ligand superfamily member 11 [KO:K05473]
699970  TNFRSF12A; tumor necrosis factor receptor superfamily member 12A isoform X2 [KO:K05149]
700068  BMP10; bone morphogenetic protein 10 [KO:K22670]
700193  IL1A; interleukin-1 alpha precursor [KO:K04383]
700201  IL11RA; interleukin-11 receptor subunit alpha isoform X3 [KO:K05056]
700407  CXCR2; C-X-C chemokine receptor type 2 [KO:K05050]
700440  IL23R; interleukin-23 receptor [KO:K05065]
700579  IL37; LOW QUALITY PROTEIN: interleukin-37 [KO:K05485]
700588  TNFSF9; tumor necrosis factor ligand superfamily member 9 [KO:K05472]
700677  IL12RB2; interleukin-12 receptor subunit beta-2 [KO:K05064]
700822  IL36G; interleukin-36 gamma [KO:K05487]
700885  GHV; growth hormone variant precursor [KO:K05438]
700959  CNTFR; ciliary neurotrophic factor receptor subunit alpha precursor [KO:K05059]
701080  CD70; CD70 antigen [KO:K05470]
701126  GDF6; growth/differentiation factor 6 [KO:K20012]
701300  IL36B; interleukin-36 beta [KO:K05486]
701451  TNFSF14; tumor necrosis factor ligand superfamily member 14 [KO:K05477]
701655  IL31; interleukin-31 [KO:K22631]
701658  IL1RN; interleukin-1 receptor antagonist protein isoform X1 [KO:K05481]
701792  CXCR5; C-X-C chemokine receptor type 5 isoform X1 [KO:K04190]
701850  TNFRSF11B; tumor necrosis factor receptor superfamily member 11B [KO:K05148]
701907  CNTF; ciliary neurotrophic factor [KO:K05420]
701946  [KO:K05506]
702067  [KO:K05505]
702462  GDF7; growth/differentiation factor 7 [KO:K20013]
702532  CSF1; macrophage colony-stimulating factor 1 isoform X1 [KO:K05453]
702734  INHBA; inhibin beta A chain [KO:K04667]
702822  AMHR2; anti-Muellerian hormone type-2 receptor isoform X2 [KO:K04672] [EC:2.7.11.30]
702944  TNFSF8; tumor necrosis factor ligand superfamily member 8 [KO:K05471]
703088  TGFBR2; TGF-beta receptor type-2 precursor [KO:K04388] [EC:2.7.11.30]
703189  TNFSF15; tumor necrosis factor ligand superfamily member 15 [KO:K05478]
703205  IL12A; interleukin-12 subunit alpha [KO:K05406]
703222  [KO:K05506]
703239  TGFB3; transforming growth factor beta-3 precursor [KO:K13377]
703334  PPBP; platelet basic protein [KO:K10029]
703390  [KO:K05505]
703451  [KO:K05407]
703744  TNFRSF25; tumor necrosis factor receptor superfamily member 25 [KO:K05160]
703895  PF4V1; platelet factor 4 variant isoform X2 [KO:K05407]
704088  BMPR2; bone morphogenetic protein receptor type-2 precursor [KO:K04671] [EC:2.7.11.30]
704133  CXCL6; C-X-C motif chemokine 6 [KO:K05506]
704266  IL9R; interleukin-9 receptor [KO:K05073]
704383  IL10RA; interleukin-10 receptor subunit alpha [KO:K05134]
704649  IL5RA; interleukin-5 receptor subunit alpha [KO:K05067]
704673  RELL2; RELT-like protein 2 [KO:K26541]
704701  IL1B; interleukin-1 beta precursor [KO:K04519]
704890  IL20RA; interleukin-20 receptor subunit alpha isoform X3 [KO:K05136]
705101  TNFRSF21; tumor necrosis factor receptor superfamily member 21 [KO:K05157]
705136  IL36A; interleukin-36 alpha [KO:K05484]
705268  IL36RN; interleukin-36 receptor antagonist protein [KO:K05483]
705404  IL4R; interleukin-4 receptor subunit alpha isoform X2 [KO:K05071]
705432  GDF5; growth/differentiation factor 5 [KO:K04664]
705457  CCR4; C-C chemokine receptor type 4 [KO:K04179]
705474  BMPR1B; bone morphogenetic protein receptor type-1B [KO:K13578] [EC:2.7.11.30]
705759  IL21R; interleukin-21 receptor [KO:K05075]
705819  IL6; interleukin-6 precursor [KO:K05405]
706012  IL10RB; interleukin-10 receptor subunit beta isoform X2 [KO:K05135]
706194  TSLP; thymic stromal lymphopoietin [KO:K05436]
706255  TNFSF4; tumor necrosis factor ligand superfamily member 4 [KO:K05469]
706946  IL3; interleukin-3 precursor [KO:K04736]
707017  ACVR2A; activin receptor type-2A isoform X1 [KO:K04670] [EC:2.7.11.30]
707034  TNFRSF19; tumor necrosis factor receptor superfamily member 19 isoform X1 [KO:K05155]
707052  PRL; prolactin precursor [KO:K05439]
707234  IFNK; interferon kappa [KO:K05441]
707329  CXCR4; C-X-C chemokine receptor type 4 [KO:K04189]
707540  TGFB2; transforming growth factor beta-2 precursor [KO:K13376]
707708  GDF11; growth/differentiation factor 11 [KO:K22679]
707749  CD40; tumor necrosis factor receptor superfamily member 5 precursor [KO:K03160]
708017  IL2; interleukin-2 precursor [KO:K05429]
708108  CXCL17; C-X-C motif chemokine 17 [KO:K22627]
708123  IL17A; interleukin-17A [KO:K05489]
708125  IL21; interleukin-21 precursor [KO:K05434]
708220  IL17F; interleukin-17F precursor [KO:K05494]
708281  TNFRSF9; tumor necrosis factor receptor superfamily member 9 precursor [KO:K05146]
708339  IL13RA2; interleukin-13 receptor subunit alpha-2 [KO:K05077]
708678  IL27; interleukin-27 subunit alpha [KO:K22629]
709005  IL17RA; interleukin-17 receptor A [KO:K05164]
709034  IL34; interleukin-34 precursor [KO:K22633]
709559  IFNA13; interferon alpha-1/13 precursor [KO:K05414]
709719  IL31RA; interleukin-31 receptor subunit alpha [KO:K22630]
709755  IFNA8; interferon alpha-8 [KO:K05414]
709948  IFNA2; interferon alpha-2 precursor [KO:K05414]
710114  MSTN; growth/differentiation factor 8 precursor [KO:K05497]
710244  EDA2R; tumor necrosis factor receptor superfamily member 27 [KO:K05163]
710424  NODAL; nodal homolog [KO:K04666]
710487  [KO:K05414]
710528  [KO:K05414]
710568  [KO:K05414]
710618  IL17C; interleukin-17C [KO:K05491]
710622  IL5; interleukin-5 precursor [KO:K05428]
710654  IFNA10; interferon alpha-4 precursor [KO:K05414]
710679  IL17B; interleukin-17B [KO:K05490]
710751  [KO:K05414]
710848  [KO:K05414]
710986  IL13RA1; interleukin-13 receptor subunit alpha-1 [KO:K05076]
711088  [KO:K05414]
711252  IFNA21; interferon alpha-21 [KO:K05414]
711255  CCR10; C-C chemokine receptor type 10 [KO:K04185]
711329  [KO:K05440]
711414  IFNB1; interferon beta precursor [KO:K05415]
711441  GDF10; growth/differentiation factor 10 [KO:K22674]
711512  CSF1R; macrophage colony-stimulating factor 1 receptor [KO:K05090] [EC:2.7.10.1]
711516  GDF2; growth/differentiation factor 2 [KO:K05503]
711625  IFNLR1; interferon lambda receptor 1 isoform X1 [KO:K05140]
711638  IL1R2; interleukin-1 receptor type 2 precursor [KO:K04387]
711681  NGF; beta-nerve growth factor [KO:K02582]
711726  IL1R1; interleukin-1 receptor type 1 [KO:K04386]
711812  IL1RL2; interleukin-1 receptor-like 2 [KO:K05172]
711893  IL1RL1; interleukin-1 receptor-like 1 isoform X2 [KO:K05171]
711989  BMP5; bone morphogenetic protein 5 [KO:K04663]
712046  IL18RAP; interleukin-18 receptor accessory protein [KO:K05174]
712076  CXCL14; C-X-C motif chemokine 14 precursor [KO:K10033]
712212  TNFRSF17; tumor necrosis factor receptor superfamily member 17 [KO:K05153]
712292  IL9; interleukin-9 [KO:K05432]
712550  LTBR; tumor necrosis factor receptor superfamily member 3 precursor [KO:K03159]
712554  CLCF1; cardiotrophin-like cytokine factor 1 isoform X1 [KO:K05421]
712577  TNFRSF13C; tumor necrosis factor receptor superfamily member 13C [KO:K05151]
712627  IL23A; interleukin-23 subunit alpha precursor [KO:K05426]
712788  IL15RA; interleukin-15 receptor subunit alpha isoform 2 precursor [KO:K05074]
712792  GDF9; growth/differentiation factor 9 [KO:K22673]
713368  CCR3; C-C chemokine receptor type 3 [KO:K04178]
713485  CSF3R; granulocyte colony-stimulating factor receptor isoform X1 [KO:K05061]
713622  XCR1; chemokine XC receptor 1 [KO:K04193]
713807  CD4; T-cell surface glycoprotein CD4 precursor [KO:K06454]
713829  CXCR6; C-X-C chemokine receptor type 6 [KO:K04191]
713850  CTF1; cardiotrophin-1 isoform X3 [KO:K05422]
713903  [KO:K24382]
713934  CCR9; C-C chemokine receptor type 9 [KO:K04184]
713943  IL25; interleukin-25 isoform X2 [KO:K05493]
714546  EPOR; erythropoietin receptor [KO:K05079]
714640  INHBC; inhibin beta C chain [KO:K22688]
714695  INHBE; inhibin beta E chain [KO:K22689]
714751  CCL7; C-C motif chemokine 7 [KO:K05509]
714907  CCL13; C-C motif chemokine 13 [KO:K16595]
714952  TGFBR1; TGF-beta receptor type-1 isoform X2 [KO:K04674] [EC:2.7.11.30]
715425  LTA; lymphotoxin-alpha precursor [KO:K05468]
715454  TNFRSF1B; tumor necrosis factor receptor superfamily member 1B precursor [KO:K05141]
715456  LIF; leukemia inhibitory factor isoform X1 [KO:K05419]
715467  TNF; tumor necrosis factor [KO:K03156]
715518  LTB; lymphotoxin-beta [KO:K03157]
715605  GDF3; growth/differentiation factor 3 [KO:K22672]
716050  CCL24; C-C motif chemokine 24 precursor [KO:K21097]
716099  CCL26; C-C motif chemokine 26 [KO:K21096]
716650  TNFRSF10B; tumor necrosis factor receptor superfamily member 10B isoform X1 [KO:K04722]
716690  IL6R; interleukin-6 receptor subunit alpha isoform X2 [KO:K05055]
716765  CCL14; C-C motif chemokine 14 [KO:K21092]
716769  IL20RB; interleukin-20 receptor subunit beta [KO:K05137]
716826  TNFRSF10A; tumor necrosis factor receptor superfamily member 10A [KO:K04722]
716901  TNFRSF10D; tumor necrosis factor receptor superfamily member 10D [KO:K22702]
717301  IL33; interleukin-33 isoform X1 [KO:K12967]
717539  AMH; muellerian-inhibiting factor [KO:K04665]
717549  IL27RA; interleukin-27 receptor subunit alpha [KO:K19598]
717562  CSH2; chorionic somatomammotropin hormone 2 precursor [KO:K05438]
717701  ACKR4; atypical chemokine receptor 4 [KO:K04186]
717994  OSM; oncostatin-M precursor [KO:K05418]
718027  IL26; interleukin-26 [KO:K05446]
718047  IL22; interleukin-22 precursor [KO:K05445]
718116  CSH4; somatotropin precursor [KO:K05438]
718135  CSH3; chorionic somatommamotropin hormone 3 precursor [KO:K05438]
718143  RELT; tumor necrosis factor receptor superfamily member 19L isoform X1 [KO:K05156]
718156  GH1; somatotropin precursor [KO:K05438]
718330  BMP2; bone morphogenetic protein 2 [KO:K21283]
718474  [KO:K05438]
718677  [KO:K16622]
719008  CCL16; C-C motif chemokine 16 [KO:K21093]
719264  IL22RA1; interleukin-22 receptor subunit alpha-1 isoform X1 [KO:K05138]
719294  EPO; erythropoietin precursor [KO:K05437]
719466  GDF15; growth/differentiation factor 15 [KO:K05504]
720298  GDF1; embryonic growth/differentiation factor 1 [KO:K05495]
721163  IL17D; interleukin-17D isoform X1 [KO:K05492]
721566  CXCL16; C-X-C motif chemokine 16 [KO:K10035]
721832  EBI3; interleukin-27 subunit beta [KO:K24476]
722033  TNFRSF1A; tumor necrosis factor receptor superfamily member 1A [KO:K03158]
722773  TNFRSF8; tumor necrosis factor receptor superfamily member 8 isoform X2 [KO:K05145]
722817  IL11; interleukin-11 [KO:K05417]
735307  [KO:K05438]
735311  CCR5; C-C chemokine receptor type 5 [KO:K04180]
Reference
  Authors
Turner MD, Nedjai B, Hurst T, Pennington DJ
  Title
Cytokines and chemokines: At the crossroads of cell signalling and inflammatory disease.
  Journal
Biochim Biophys Acta 1843:2563-2582 (2014)
DOI:10.1016/j.bbamcr.2014.05.014
Reference
  Authors
Brocker C, Thompson D, Matsumoto A, Nebert DW, Vasiliou V
  Title
Evolutionary divergence and functions of the human interleukin (IL) gene family.
  Journal
Hum Genomics 5:30-55 (2010)
DOI:10.1186/1479-7364-5-1-30
Reference
  Authors
Akdis M, Aab A, Altunbulakli C, Azkur K, Costa RA, Crameri R, Duan S, Eiwegger T, Eljaszewicz A, Ferstl R, Frei R, Garbani M, Globinska A, Hess L, Huitema C, Kubo T, Komlosi Z, Konieczna P, Kovacs N, Kucuksezer UC, Meyer N, Morita H, Olzhausen J, O'Mahony L, Pezer M, Prati M, Rebane A, Rhyner C, Rinaldi A, Sokolowska M, Stanic B, Sugita K, Treis A, van de Veen W, Wanke K, Wawrzyniak M, Wawrzyniak P, Wirz OF, Zakzuk JS, Akdis CA
  Title
Interleukins (from IL-1 to IL-38), interferons, transforming growth factor beta, and TNF-alpha: Receptors, functions, and roles in diseases.
  Journal
J Allergy Clin Immunol 138:984-1010 (2016)
DOI:10.1016/j.jaci.2016.06.033
Reference
  Authors
Boulanger MJ, Garcia KC
  Title
Shared cytokine signaling receptors: structural insights from the gp130 system.
  Journal
Adv Protein Chem 68:107-46 (2004)
DOI:10.1016/S0065-3233(04)68004-1
Reference
  Authors
Allan SM, Tyrrell PJ, Rothwell NJ
  Title
Interleukin-1 and neuronal injury.
  Journal
Nat Rev Immunol 5:629-40 (2005)
DOI:10.1038/nri1664
Reference
  Authors
Lopetuso LR, Chowdhry S, Pizarro TT
  Title
Opposing Functions of Classic and Novel IL-1 Family Members in Gut Health and Disease.
  Journal
Front Immunol 4:181 (2013)
DOI:10.3389/fimmu.2013.00181
Reference
  Authors
Iwakura Y, Ishigame H, Saijo S, Nakae S
  Title
Functional specialization of interleukin-17 family members.
  Journal
Immunity 34:149-62 (2011)
DOI:10.1016/j.immuni.2011.02.012
Reference
  Authors
Fischer P, Hilfiker-Kleiner D
  Title
Survival pathways in hypertrophy and heart failure: the gp130-STAT3 axis.
  Journal
Basic Res Cardiol 102:279-97 (2007)
DOI:10.1007/s00395-007-0658-z
Reference
  Authors
Richards CD
  Title
The enigmatic cytokine oncostatin m and roles in disease.
  Journal
ISRN Inflamm 2013:512103 (2013)
DOI:10.1155/2013/512103
Reference
  Authors
Zhang Q, Putheti P, Zhou Q, Liu Q, Gao W
  Title
Structures and biological functions of IL-31 and IL-31 receptors.
  Journal
Cytokine Growth Factor Rev 19:347-56 (2008)
DOI:10.1016/j.cytogfr.2008.08.003
Reference
  Authors
Meenhuis A, Verwijmeren C, Roovers O, Touw IP
  Title
The deubiquitinating enzyme DUB2A enhances CSF3 signalling by attenuating lysosomal routing of the CSF3 receptor.
  Journal
Biochem J 434:343-51 (2011)
DOI:10.1042/BJ20101628
Reference
  Authors
de Weerd NA, Nguyen T
  Title
The interferons and their receptors--distribution and regulation.
  Journal
Immunol Cell Biol 90:483-91 (2012)
DOI:10.1038/icb.2012.9
Reference
  Authors
Aggarwal BB
  Title
Signalling pathways of the TNF superfamily: a double-edged sword.
  Journal
Nat Rev Immunol 3:745-56 (2003)
DOI:10.1038/nri1184
Reference
  Authors
Ashkenazi A
  Title
Targeting death and decoy receptors of the tumour-necrosis factor superfamily.
  Journal
Nat Rev Cancer 2:420-30 (2002)
DOI:10.1038/nrc821
Reference
  Authors
Seeger P, Musso T, Sozzani S
  Title
The TGF-beta superfamily in dendritic cell biology.
  Journal
Cytokine Growth Factor Rev 26:647-57 (2015)
DOI:10.1016/j.cytogfr.2015.06.002
Reference
  Authors
Wakefield LM, Hill CS
  Title
Beyond TGFbeta: roles of other TGFbeta superfamily members in cancer.
  Journal
Nat Rev Cancer 13:328-41 (2013)
DOI:10.1038/nrc3500
Reference
  Authors
Mueller TD, Nickel J
  Title
Promiscuity and specificity in BMP receptor activation.
  Journal
FEBS Lett 586:1846-59 (2012)
DOI:10.1016/j.febslet.2012.02.043
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