KEGG   PATHWAY: xgl05132
Entry
xgl05132                    Pathway                                
Name
Salmonella infection - Xiphias gladius (swordfish)
Description
Salmonella infection usually presents as a self-limiting gastroenteritis or the more severe typhoid fever and bacteremia. The common disease-causing Salmonella species in human is a single species, Salmonella enterica, which has numerous serovars.
Following intestinal colonization Salmonella inject effector proteins into the host cells using a type III secretion system (T3SS), T3SS1. Then a small group of effector proteins induce rearrangement of the actin cytoskeleton resulting in membrane ruffles and rapid internalization of the bacteria.The T3SS2 is responsible for translocating effector proteins that direct Salmonella-containing vacuole (SCV) maturation. The majority of the bacteria are known to survive and replicate in SCV.
Class
Human Diseases; Infectious disease: bacterial
Pathway map
xgl05132  Salmonella infection
xgl05132

Disease
H00111  Typhoid fever
Organism
Xiphias gladius (swordfish) [GN:xgl]
Gene
120782914  [KO:K07897]
120782944  mapk3; mitogen-activated protein kinase 3 [KO:K04371] [EC:2.7.11.24]
120782946  tubb1; tubulin beta-1 chain isoform X1 [KO:K07375]
120783058  dynlrb1; dynein light chain roadblock-type 1 isoform X1 [KO:K10419]
120783081  myl9b; myosin regulatory light polypeptide 9b [KO:K12755]
120783086  dctn2; dynactin subunit 2 [KO:K10424]
120783110  [KO:K05755]
120783203  brk1; probable protein BRICK1 [KO:K05752]
120783206  mapk14b; mitogen-activated protein kinase 14B isoform X1 [KO:K04441] [EC:2.7.11.24]
120783275  arl8bb; ADP-ribosylation factor-like 8Bb [KO:K07955]
120783284  mych; myelocytomatosis oncogene homolog [KO:K04377]
120783296  arl8ba; ADP-ribosylation factor-like protein 8B-A [KO:K07955]
120783311  kif5ab; kinesin heavy chain [KO:K10396] [EC:5.6.1.3]
120783329  si:dkey-13a21.4; ras-related protein rab7 [KO:K07897]
120783408  cse1l; exportin-2 [KO:K18423]
120783613  cyth2; cytohesin-2 [KO:K18441]
120784018  pycard; apoptosis-associated speck-like protein containing a CARD [KO:K12799]
120784098  tubb5; tubulin beta-5 chain isoform X1 [KO:K07375]
120784104  tnfrsf1a; tumor necrosis factor receptor superfamily member 1A isoform X1 [KO:K03158]
120784111  gapdh; glyceraldehyde-3-phosphate dehydrogenase [KO:K00134] [EC:1.2.1.12]
120784117  m6pr; cation-dependent mannose-6-phosphate receptor [KO:K10089]
120784131  cdc42l; cell division cycle 42, like [KO:K04393]
120784191  dctn3; dynactin subunit 3 [KO:K10425]
120784198  tlr18; toll-like receptor 18 isoform X1 [KO:K10159]
120784256  s100a10b; protein S100-A10b [KO:K17274]
120784263  nod1; nucleotide-binding oligomerization domain-containing protein 1 isoform X1 [KO:K08727]
120784265  tnfb; tumor necrosis factor b (TNF superfamily, member 2) [KO:K03156]
120784336  rab5ab; RAB5A, member RAS oncogene family, b [KO:K07887]
120784547  zgc:86896; actin-related protein 2/3 complex subunit 1A-A [KO:K05757]
120784597  arf2a; ADP-ribosylation factor 2a [KO:K07937]
120784650  ctnnb1; catenin beta-1 isoform X1 [KO:K02105]
120784688  dnm2a; dynamin-3 isoform X1 [KO:K23484]
120784811  pkn1b; serine/threonine-protein kinase N1b isoform X1 [KO:K06071] [EC:2.7.11.13]
120785033  ahnak; neuroblast differentiation-associated protein AHNAK isoform X1 [KO:K23934]
120785088  rhogd; ras homolog gene family, member Gd [KO:K07863]
120785116  cyfip2; cytoplasmic FMR1-interacting protein 2 [KO:K05749]
120785165  [KO:K02580]
120785250  rab5c; ras-related protein Rab-5C [KO:K07889]
120785392  [KO:K02187] [EC:3.4.22.56]
120785433  mapk9; mitogen-activated protein kinase 9 [KO:K04440] [EC:2.7.11.24]
120785589  dctn4; dynactin subunit 4 [KO:K10426]
120785769  rab9b; ras-related protein Rab-9B [KO:K07900]
120785905  [KO:K10415]
120785943  [KO:K08738]
120785959  mylpfa; myosin light chain, phosphorylatable, fast skeletal muscle a [KO:K12758]
120785969  s100a10a; protein S100-A10a [KO:K17274]
120786074  [KO:K07375]
120786190  dync1li1; cytoplasmic dynein 1 light intermediate chain 1 isoform X1 [KO:K10416]
120786223  anxa14; annexin A2 [KO:K17092]
120786228  elmo1; engulfment and cell motility protein 1 [KO:K12366]
120786240  [KO:K00134] [EC:1.2.1.12]
120786289  [KO:K02105]
120786357  tnfa; tumor necrosis factor a (TNF superfamily, member 2) [KO:K03156]
120786412  [KO:K05405]
120786424  [KO:K04393]
120786746  [KO:K07887]
120786834  map2k4a; dual specificity mitogen-activated protein kinase kinase 4a isoform X1 [KO:K04430] [EC:2.7.12.2]
120787086  [KO:K05759]
120787151  [KO:K07374]
120787454  vps16; vacuolar protein sorting-associated protein 16 homolog isoform X1 [KO:K20180]
120787456  [KO:K17923]
120787843  [KO:K04734]
120788025  [KO:K02159]
120788031  tubb4bl; tubulin beta-4B chain isoform X1 [KO:K07375]
120788228  cyth4a; cytohesin-2 isoform X1 [KO:K18441]
120788265  cyth3b; cytohesin-3 isoform X1 [KO:K18441]
120788362  txn2; thioredoxin, mitochondrial [KO:K03671]
120788415  [KO:K02159]
120788717  traf6; TNF receptor-associated factor 6 [KO:K03175] [EC:2.3.2.27]
120788739  map3k7; mitogen-activated protein kinase kinase kinase 7 isoform X1 [KO:K04427] [EC:2.7.11.25]
120788764  arf6a; ADP-ribosylation factor 6a [KO:K07941]
120788774  myo6a; myosin VIa isoform X1 [KO:K10358]
120788791  [KO:K17388] [EC:2.7.11.39]
120788807  hsp90ab1; heat shock protein HSP 90-beta [KO:K04079]
120788809  snx9b; sorting nexin-9b isoform X1 [KO:K17923]
120788852  [KO:K07856]
120789016  tab2; TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 isoform X1 [KO:K04404]
120789017  actr10; actin-related protein 10 [KO:K16576]
120789116  hsp90aa1.2; heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2 [KO:K04079]
120789117  hsp90aa1.1; heat shock protein HSP 90-alpha 1 [KO:K04079]
120789178  [KO:K04379]
120789218  acbd3; Golgi resident protein GCP60 [KO:K23935]
120789247  vps18; vacuolar protein sorting-associated protein 18 homolog [KO:K20181]
120789262  dynlt1b; dynein light chain Tctex-type 1 [KO:K10420]
120789444  fosab; v-fos FBJ murine osteosarcoma viral oncogene homolog Ab [KO:K04379]
120789537  myca; transcriptional regulator Myc-A isoform X1 [KO:K04377]
120789612  ralaa; ras-related protein Ral-A isoform X1 [KO:K07834]
120789617  abi1a; abl interactor 1a isoform X1 [KO:K23649]
120789626  myl12.1; myosin, light chain 12, genome duplicate 1 [KO:K12757]
120789653  kpna1; importin subunit alpha-5 [KO:K23940]
120789782  [KO:K04729]
120789847  [KO:K10396] [EC:5.6.1.3]
120789889  tubb6; tubulin beta chain isoform X1 [KO:K07375]
120789897  actr3b; actin-related protein 3B isoform X1 [KO:K18584]
120789915  [KO:K02161]
120790035  tnfsf10; tumor necrosis factor ligand superfamily member 10 [KO:K04721]
120790076  vps41; vacuolar protein sorting-associated protein 41 homolog isoform X1 [KO:K20184]
120790144  wasf3b; wiskott-Aldrich syndrome protein family member 3b [KO:K06083]
120790533  ptprc; receptor-type tyrosine-protein phosphatase C isoform X1 [KO:K06478] [EC:3.1.3.48]
120790721  exoc2; exocyst complex component 2 isoform X1 [KO:K17637]
120790750  fyco1a; FYVE and coiled-coil domain-containing protein 1 [KO:K21954]
120790948  [KO:K05759]
120790967  arpc5b; actin-related protein 2/3 complex subunit 5b [KO:K05754]
120791009  map2k2a; dual specificity mitogen-activated protein kinase kinase 2a [KO:K04369] [EC:2.7.12.2]
120791035  cyfip1; cytoplasmic FMR1-interacting protein 1 homolog [KO:K05749]
120791116  [KO:K17092]
120791244  tab3; TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 [KO:K12793]
120791293  jun; transcription factor AP-1 isoform X1 [KO:K04448]
120791340  [KO:K00922] [EC:2.7.1.153]
120791497  dynll2a; dynein, light chain, LC8-type 2a [KO:K10418]
120791502  [KO:K13744]
120791551  kpna4; importin subunit alpha-3 [KO:K23583]
120791651  [KO:K13883]
120791733  dync1li2; cytoplasmic dynein 1 light intermediate chain 2 isoform X1 [KO:K10416]
120791739  [KO:K01370] [EC:3.4.22.36]
120791823  klc3; kinesin light chain 3 isoform X1 [KO:K10407]
120791831  rps3; 40S ribosomal protein S3 [KO:K02985]
120791894  akt2; RAC-beta serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
120791909  pik3cb; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
120792090  [KO:K05403]
120792359  [KO:K10414]
120792487  pak1; serine/threonine-protein kinase PAK 1 isoform X1 [KO:K04409] [EC:2.7.11.1]
120792559  fhod1; FH1/FH2 domain-containing protein 1 isoform X1 [KO:K23938]
120792675  [KO:K17092]
120792700  pik3c2g; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma isoform X1 [KO:K00923] [EC:2.7.1.154]
120792735  [KO:K02833]
120792776  [KO:K08847] [EC:2.7.11.1]
120792797  mapk12a; mitogen-activated protein kinase 12 [KO:K04441] [EC:2.7.11.24]
120792953  snx33; sorting nexin-33 isoform X1 [KO:K17923]
120792990  irak4; interleukin-1 receptor-associated kinase 4 isoform X1 [KO:K04733] [EC:2.7.11.1]
120793021  pik3c2a; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha [KO:K00923] [EC:2.7.1.154]
120793059  hsp90b1; endoplasmin [KO:K09487]
120793562  map2k1; dual specificity mitogen-activated protein kinase kinase 1 isoform X1 [KO:K04368] [EC:2.7.12.2]
120793696  [KO:K10419]
120793742  [KO:K08849] [EC:2.7.11.1]
120793771  wasla; WASP like actin nucleation promoting factor a [KO:K23612]
120793897  casp7; caspase-7 [KO:K04397] [EC:3.4.22.60]
120793976  map2k4b; dual specificity mitogen-activated protein kinase kinase 4b isoform X1 [KO:K04430] [EC:2.7.12.2]
120794076  tcf7l2; transcription factor 7-like 2 isoform X1 [KO:K04491]
120794111  map2k6; dual specificity mitogen-activated protein kinase kinase 6 isoform X1 [KO:K04433] [EC:2.7.12.2]
120794157  [KO:K18441]
120794226  arf2b; ADP-ribosylation factor 2b [KO:K07937]
120794257  [KO:K04467] [EC:2.7.11.10]
120794275  [KO:K18441]
120794394  mapk8b; mitogen-activated protein kinase 8 [KO:K04440] [EC:2.7.11.24]
120794582  plekhm1; pleckstrin homology domain-containing family M member 1 isoform X1 [KO:K23282]
120794782  [KO:K07889]
120794829  rac1a; ras-related C3 botulinum toxin substrate 1 [KO:K04392]
120794855  exoc7; LOW QUALITY PROTEIN: exocyst complex component 7 [KO:K07195]
120794959  dync1h1; cytoplasmic dynein 1 heavy chain 1 [KO:K10413]
120795051  [KO:K04427] [EC:2.7.11.25]
120795086  klc1a; kinesin light chain 1 isoform X1 [KO:K10407]
120795111  zgc:153993; apoptosis regulator BAX [KO:K02159]
120795120  rock2a; rho-associated protein kinase 2 isoform X1 [KO:K17388] [EC:2.7.11.39]
120795160  exoc5; exocyst complex component 5 [KO:K19984]
120795178  [KO:K07375]
120795231  fbxo22; F-box only protein 22 [KO:K10302]
120795309  [KO:K23934]
120795320  akt1; RAC-alpha serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
120795438  [KO:K04721]
120795515  vps39; vam6/Vps39-like protein isoform X1 [KO:K20183]
120795587  fosaa; proto-oncogene c-Fos [KO:K04379]
120795680  arf6b; ADP-ribosylation factor 6b [KO:K07941]
120795821  nfkbiab; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b [KO:K04734]
120795846  dctn1b; dynactin subunit 1 isoform X1 [KO:K04648]
120796054  [KO:K04467] [EC:2.7.11.10]
120796205  mapk8a; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
120796255  nckap1; nck-associated protein 1 [KO:K05750]
120796259  klc1b; kinesin light chain 1b isoform X1 [KO:K10407]
120796664  [KO:K17260]
120796795  [KO:K08738]
120796841  dync2li1; cytoplasmic dynein 2 light intermediate chain 1 [KO:K10417]
120796885  akt3a; RAC-gamma serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
120797016  [KO:K00922] [EC:2.7.1.153]
120797023  ripk3; receptor-interacting serine/threonine-protein kinase 3 [KO:K08847] [EC:2.7.11.1]
120797026  rela; transcription factor p65 isoform X1 [KO:K04735]
120797169  zgc:101810; actin-related protein 2 isoform X1 [KO:K17260]
120797205  si:ch211-63p21.2; FH1/FH2 domain-containing protein 1 isoform X1 [KO:K23938]
120797238  tlr2; toll-like receptor 2 isoform X1 [KO:K10159]
120797311  pfn1; profilin-1 [KO:K05759]
120797365  txn; thioredoxin [KO:K03671]
120797408  [KO:K04648]
120797474  zgc:109889; LOW QUALITY PROTEIN: wiskott-Aldrich syndrome protein family member 3 [KO:K06083]
120797476  dctn6; dynactin subunit 6 [KO:K10428]
120797480  [KO:K10030]
120797507  klc2; kinesin light chain 2 [KO:K10407]
120797524  cxcl19; C-X-C motif chemokine 19 [KO:K10030]
120797631  pik3c3; phosphatidylinositol 3-kinase catalytic subunit type 3 [KO:K00914] [EC:2.7.1.137]
120797934  [KO:K07374]
120797994  [KO:K07374]
120798000  [KO:K07374]
120798072  [KO:K07899]
120798107  [KO:K10396] [EC:5.6.1.3]
120798151  arpc2; actin-related protein 2/3 complex subunit 2 [KO:K05758]
120798161  [KO:K10420]
120798288  [KO:K07374]
120798336  [KO:K18584]
120798519  arf1; ADP-ribosylation factor 1 [KO:K07937]
120798531  [KO:K10415]
120798605  mapk11; mitogen-activated protein kinase 11 [KO:K04441] [EC:2.7.11.24]
120798627  map2k2b; dual specificity mitogen-activated protein kinase kinase 2b [KO:K04369] [EC:2.7.12.2]
120798667  myl12.2; myosin, light chain 12, genome duplicate 2 [KO:K12757]
120798705  [KO:K05754]
120798723  [KO:K10396] [EC:5.6.1.3]
120798756  [KO:K23649]
120798781  pik3cg; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform isoform X1 [KO:K21289] [EC:2.7.1.153]
120799017  [KO:K05759]
120799023  [KO:K00922] [EC:2.7.1.153]
120799066  [KO:K21954]
120799083  casp8; caspase-8 isoform X1 [KO:K04398] [EC:3.4.22.61]
120799085  [KO:K04398] [EC:3.4.22.61]
120799207  [KO:K08846] [EC:2.7.11.1]
120799277  bcl2b; apoptosis regulator Bcl-2 [KO:K02161]
120799298  [KO:K07375]
120799349  ripk1l; receptor-interacting serine/threonine-protein kinase 1 isoform X1 [KO:K02861] [EC:2.7.11.1]
120799405  [KO:K04448]
120799601  cyth4b; cytohesin 4b isoform X1 [KO:K18441]
120799710  [KO:K10030]
120799714  actb1; actin, cytoplasmic 1 isoform X1 [KO:K05692]
120799728  rhoh; rho-related GTP-binding protein RhoH [KO:K07873]
120799817  tradd; tumor necrosis factor receptor type 1-associated DEATH domain protein [KO:K03171]
120799883  arpc1b; actin-related protein 2/3 complex subunit 1B [KO:K05757]
120799885  arpc1a; actin-related protein 2/3 complex subunit 1A [KO:K05757]
120799943  akt3b; RAC-gamma serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
120799949  pkn1a; serine/threonine-protein kinase N1 isoform X1 [KO:K06071] [EC:2.7.11.13]
120800045  [KO:K07375]
120800101  [KO:K10030]
120800118  [KO:K04377]
120800202  map2k7; dual specificity mitogen-activated protein kinase kinase 7 isoform X1 [KO:K04431] [EC:2.7.12.2]
120800214  [KO:K04441] [EC:2.7.11.24]
120800237  lef1; lymphoid enhancer-binding factor 1 isoform X1 [KO:K04492]
120800249  [KO:K06083]
120800283  exoc4; exocyst complex component 4 isoform X1 [KO:K06111]
120800309  [KO:K23934]
120800321  [KO:K23937]
120800498  fadd; protein FADD [KO:K02373]
120800521  [KO:K23484]
120800586  casp3a; caspase-3a [KO:K02187] [EC:3.4.22.56]
120800722  waslb; WASP like actin nucleation promoting factor b isoform X1 [KO:K23612]
120800783  tab1; TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 isoform X1 [KO:K04403]
120800830  actr2a; actin-related protein 2-A isoform X1 [KO:K17260]
120801236  [KO:K10420]
120801272  rab9a; ras-related protein Rab-9A [KO:K07899]
120801380  [KO:K20282]
120801450  [KO:K10396] [EC:5.6.1.3]
120801507  [KO:K08738]
120801582  [KO:K18584]
120801759  kpna3; importin subunit alpha-4 [KO:K23583]
120801854  dync1i2a; dynein, cytoplasmic 1, intermediate chain 2a [KO:K10415]
120801861  casp10; caspase-8 isoform X1 [KO:K04398] [EC:3.4.22.61]
120801909  rab5b; ras-related protein Rab-5B [KO:K07888]
120802014  [KO:K07374]
120802015  [KO:K07374]
120802016  [KO:K07374]
120802267  [KO:K05733] [EC:2.7.11.1]
120802393  podxl; podocalyxin [KO:K06817]
120802425  dynll2b; dynein, light chain, LC8-type 2b [KO:K10418]
120802518  rhogb; ras homolog family member Gb [KO:K07863]
120802566  [KO:K12756]
120802797  wasf3a; wiskott-Aldrich syndrome protein family member 3 [KO:K06083]
120802835  [KO:K07374]
120802926  [KO:K04456] [EC:2.7.11.1]
120802962  birc2; baculoviral IAP repeat-containing protein 2 [KO:K16060]
120803038  tcf7; transcription factor 7 isoform X1 [KO:K02620]
120803106  vps11; vacuolar protein sorting-associated protein 11 homolog [KO:K20179]
120803115  [KO:K07374]
120803142  skp1; S-phase kinase-associated protein 1 [KO:K03094]
120803349  tuba5; tubulin alpha 5 [KO:K07374]
120803375  raf1a; raf-1 proto-oncogene, serine/threonine kinase a isoform X1 [KO:K04366] [EC:2.7.11.1]
120803427  ikbkg; NF-kappa-B essential modulator isoform X1 [KO:K07210]
120803515  [KO:K04513]
120803517  [KO:K04513]
120803534  [KO:K07374]
120803582  rhoab; rho-related GTP-binding protein RhoA-B [KO:K04513]
120803623  plekhm2; pleckstrin homology domain-containing family M member 2 isoform X1 [KO:K15348]
120803711  [KO:K04393]
120803741  [KO:K07955]
120803801  mapk13; mitogen-activated protein kinase 13 [KO:K04441] [EC:2.7.11.24]
120803823  irak1; interleukin-1 receptor-associated kinase 1 [KO:K04730] [EC:2.7.11.1]
120803829  zgc:171775; STKc_p38 domain-containing protein [KO:K04441] [EC:2.7.11.24]
120803885  mapk14a; mitogen-activated protein kinase 14A isoform X1 [KO:K04441] [EC:2.7.11.24]
120803897  rhoaa; rho-related GTP-binding protein RhoA-A [KO:K04513]
120804015  pik3cd; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
120804053  si:rp71-17i16.5; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform [KO:K21289] [EC:2.7.1.153]
120804117  tuba1c; tubulin alpha-1C chain [KO:K07374]
120804118  [KO:K07374]
120804130  flna; filamin-A isoform X1 [KO:K04437]
120804258  kif5aa; kinesin family member 5Aa isoform X1 [KO:K10396] [EC:5.6.1.3]
120804310  si:ch211-112c15.8; tumor necrosis factor receptor superfamily member 1A [KO:K03158]
120804648  [KO:K05692]
120804661  myl7; myosin regulatory light chain 2, atrial isoform isoform X1 [KO:K12754]
120804798  dctn5; dynactin subunit 5 [KO:K10427]
120805077  [KO:K04433] [EC:2.7.12.2]
120805086  ikbkb; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1 [KO:K07209] [EC:2.7.11.10]
120805092  dynll1; dynein light chain 1, cytoplasmic [KO:K10418]
120805095  hdr; hematopoietic death receptor isoform X1 [KO:K04722]
120805149  tubb2b; tubulin beta-2b chain [KO:K07375]
120805154  snx18a; sorting nexin-18a [KO:K17923]
120805165  mapk1; mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
120805168  traf2a; TNF receptor-associated factor 2 [KO:K03173] [EC:2.3.2.27]
120805274  myl2b; myosin, light chain 2b, regulatory, cardiac, slow [KO:K10351]
120805320  [KO:K04519]
120805321  [KO:K04519]
120805718  tcf7l1b; transcription factor 7-like 1-B isoform X1 [KO:K04490]
120805788  vps33a; vacuolar protein sorting-associated protein 33A [KO:K20182]
120806021  il1b; interleukin-1 beta [KO:K04519]
120806023  actr1b; actin related protein 1B [KO:K16575]
120806038  [KO:K12753]
120806087  arpc3; actin-related protein 2/3 complex subunit 3 [KO:K05756]
120806199  traf2b; TNF receptor-associated factor 2 [KO:K03173] [EC:2.3.2.27]
120806258  [KO:K04490]
120806558  [KO:K17923]
120806563  [KO:K03173] [EC:2.3.2.27]
120806581  tnfrsfa; tumor necrosis factor receptor superfamily, member a [KO:K04722]
120806707  cyth1a; cytohesin-1a isoform X1 [KO:K18441]
120806753  mapk10; mitogen-activated protein kinase 10 [KO:K04440] [EC:2.7.11.24]
120807080  cdc42; cell division control protein 42 homolog isoform X1 [KO:K04393]
120807086  arpc4; actin-related protein 2/3 complex subunit 4 [KO:K05755]
120807186  elmo2; engulfment and cell motility protein 2 isoform X1 [KO:K18985]
120807260  actb2; actin, cytoplasmic 2 [KO:K05692]
120807274  nckap1l; nck-associated protein 1-like [KO:K05750]
120807293  [KO:K04513]
120807312  rac1b; ras-related C3 botulinum toxin substrate 1b [KO:K04392]
120807452  pik3c2b; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta [KO:K00923] [EC:2.7.1.154]
120807528  myl2a; myosin regulatory light chain 2a [KO:K10351]
120807567  [KO:K07897]
Compound
C00338  Lipopolysaccharide
C01194  1-Phosphatidyl-D-myo-inositol
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
Reference
PMID:28875943
  Authors
Bernal-Bayard J, Ramos-Morales F
  Title
Molecular Mechanisms Used by Salmonella to Evade the Immune System.
  Journal
Curr Issues Mol Biol 25:133-168 (2018)
DOI:10.21775/cimb.025.133
Reference
PMID:28848711
  Authors
Hume PJ, Singh V, Davidson AC, Koronakis V
  Title
Swiss Army Pathogen: The Salmonella Entry Toolkit.
  Journal
Front Cell Infect Microbiol 7:348 (2017)
DOI:10.3389/fcimb.2017.00348
Reference
PMID:31402916
  Authors
Wemyss MA, Pearson JS
  Title
Host Cell Death Responses to Non-typhoidal Salmonella Infection.
  Journal
Front Immunol 10:1758 (2019)
DOI:10.3389/fimmu.2019.01758
Reference
PMID:27974148
  Authors
Bierschenk D, Boucher D, Schroder K
  Title
Salmonella-induced inflammasome activation in humans.
  Journal
Mol Immunol 86:38-43 (2017)
DOI:10.1016/j.molimm.2016.11.009
Reference
PMID:29477730
  Authors
Pinaud L, Sansonetti PJ, Phalipon A
  Title
Host Cell Targeting by Enteropathogenic Bacteria T3SS Effectors.
  Journal
Trends Microbiol 26:266-283 (2018)
DOI:10.1016/j.tim.2018.01.010
Reference
PMID:25749450
  Authors
LaRock DL, Chaudhary A, Miller SI
  Title
Salmonellae interactions with host processes.
  Journal
Nat Rev Microbiol 13:191-205 (2015)
DOI:10.1038/nrmicro3420
Reference
PMID:17983751
  Authors
Ramsden AE, Holden DW, Mota LJ
  Title
Membrane dynamics and spatial distribution of Salmonella-containing vacuoles.
  Journal
Trends Microbiol 15:516-24 (2007)
DOI:10.1016/j.tim.2007.10.002
Reference
PMID:22702524
  Authors
van der Heijden J, Finlay BB
  Title
Type III effector-mediated processes in Salmonella infection.
  Journal
Future Microbiol 7:685-703 (2012)
DOI:10.2217/fmb.12.49
Reference
PMID:27222578
  Authors
Galan JE
  Title
Typhoid toxin provides a window into typhoid fever and the biology of Salmonella Typhi.
  Journal
Proc Natl Acad Sci U S A 113:6338-44 (2016)
DOI:10.1073/pnas.1606335113
Reference
PMID:19157959
  Authors
McGhie EJ, Brawn LC, Hume PJ, Humphreys D, Koronakis V
  Title
Salmonella takes control: effector-driven manipulation of the host.
  Journal
Curr Opin Microbiol 12:117-24 (2009)
DOI:10.1016/j.mib.2008.12.001
Reference
PMID:12675800
  Authors
Miao EA, Brittnacher M, Haraga A, Jeng RL, Welch MD, Miller SI
  Title
Salmonella effectors translocated across the vacuolar membrane interact with the actin cytoskeleton.
  Journal
Mol Microbiol 48:401-15 (2003)
DOI:10.1046/j.1365-2958.2003.t01-1-03456.x
Reference
PMID:17074883
  Authors
Patel JC, Galan JE
  Title
Differential activation and function of Rho GTPases during Salmonella-host cell interactions.
  Journal
J Cell Biol 175:453-63 (2006)
DOI:10.1083/jcb.200605144
Reference
PMID:18411289
  Authors
Wasylnka JA, Bakowski MA, Szeto J, Ohlson MB, Trimble WS, Miller SI, Brumell JH
  Title
Role for myosin II in regulating positioning of Salmonella-containing vacuoles and intracellular replication.
  Journal
Infect Immun 76:2722-35 (2008)
DOI:10.1128/IAI.00152-08
Reference
PMID:10499590
  Authors
Fu Y, Galan JE
  Title
A salmonella protein antagonizes Rac-1 and Cdc42 to mediate host-cell recovery after bacterial invasion.
  Journal
Nature 401:293-7 (1999)
DOI:10.1038/45829
Related
pathway
xgl04010  MAPK signaling pathway
xgl04210  Apoptosis
xgl04217  Necroptosis
xgl04621  NOD-like receptor signaling pathway
KO pathway
ko05132   

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