KEGG   PATHWAY: pon05168
Entry
pon05168                    Pathway                                
Name
Herpes simplex virus 1 infection - Pongo abelii (Sumatran orangutan)
Description
Herpes simplex virus 1(HSV-1) is a common human pathogen, which initially infects orofacial mucosal surfaces. The virus replicates in epithelial cells at these sites, causing clinically overt disease characterized by vesicular lesions. HSV-1 then penetrates to the nervous system and establishes latency in sensory neurons. Throughout the lifetime of the host, HSV-1 may reactivate from its latent state and reinitiate a lytic infection cycle. HSV-1 has developed various mechanisms to escape its host innate immune responses and increased its capacity to replicate and to persist. ICP34.5, ICP0, ICP27, Us11 and Vhs (UL41) are the proteins involved in viral interference.
Class
Human Diseases; Infectious disease: viral
Pathway map
pon05168  Herpes simplex virus 1 infection
pon05168

Organism
Pongo abelii (Sumatran orangutan) [GN:pon]
Gene
100446211  LTA; lymphotoxin-alpha [KO:K05468]
100446427  TNFSF14; tumor necrosis factor ligand superfamily member 14 isoform X1 [KO:K05477]
100437228  TNFRSF14; tumor necrosis factor receptor superfamily member 14 [KO:K05152]
100458089  TRAF2; TNF receptor-associated factor 2 [KO:K03173] [EC:2.3.2.27]
100453867  TRAF5; TNF receptor-associated factor 5 isoform X2 [KO:K09849]
100440586  IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X3 [KO:K07209] [EC:2.7.11.10]
100174735  CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [KO:K04467] [EC:2.7.11.10]
100449496  IKBKG; NF-kappa-B essential modulator isoform X5 [KO:K07210]
100459445  NF-kappa-B inhibitor alpha [KO:K04734]
100461595  NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1 [KO:K02580]
100456049  RELA; transcription factor p65 [KO:K04735]
100457858  BIRC2; baculoviral IAP repeat-containing protein 2 [KO:K16060]
100457249  BIRC3; baculoviral IAP repeat-containing protein 3 isoform X1 [KO:K16060]
100172740  CCL2; C-C motif chemokine 2 precursor [KO:K14624]
100455807  NECTIN1; nectin-1 isoform X1 [KO:K06081]
100447663  NECTIN2; nectin-2 [KO:K06531]
100449978  PILRA; paired immunoglobulin-like type 2 receptor alpha isoform X2 [KO:K15411]
100440983  PTPN11; tyrosine-protein phosphatase non-receptor type 11 isoform X1 [KO:K07293] [EC:3.1.3.48]
100453984  ITGA5; integrin alpha-5 [KO:K06484]
100445345  ITGB3; integrin beta-3 [KO:K06493]
100436498  SRC; proto-oncogene tyrosine-protein kinase Src isoform X1 [KO:K05704] [EC:2.7.10.2]
100438875  SYK; tyrosine-protein kinase SYK isoform X1 [KO:K05855] [EC:2.7.10.2]
100447342  CARD9; caspase recruitment domain-containing protein 9 [KO:K12794]
100441280  IRF3; interferon regulatory factor 3 isoform X1 [KO:K05411]
100441074  IFNB1; interferon beta [KO:K05415]
100435218  TP53; cellular tumor antigen p53 [KO:K04451]
100446798  C3; complement C3 isoform X1 [KO:K03990]
100461390  C5; complement C5 [KO:K03994]
100174400  CFP; properdin precursor [KO:K15412]
100456464  TLR2; toll-like receptor 2 isoform X1 [KO:K10159]
100440654  TLR9; toll-like receptor 9 isoform X1 [KO:K10161]
100460593  MYD88; myeloid differentiation primary response protein MyD88 isoform X1 [KO:K04729]
100460542  IRF7; interferon regulatory factor 7 isoform X2 [KO:K09447]
100442382  TLR3; toll-like receptor 3 [KO:K05401]
100455734  TICAM1; TIR domain-containing adapter molecule 1 [KO:K05842]
100447243  IRAK4; interleukin-1 receptor-associated kinase 4 isoform X1 [KO:K04733] [EC:2.7.11.1]
100437883  IRAK1; interleukin-1 receptor-associated kinase 1 isoform X2 [KO:K04730] [EC:2.7.11.1]
100449432  TRAF6; TNF receptor-associated factor 6 [KO:K03175] [EC:2.3.2.27]
100171454  MAP3K7; mitogen-activated protein kinase kinase kinase 7 [KO:K04427] [EC:2.7.11.25]
103888975  TAB1; TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 isoform X1 [KO:K04403]
100174071  TAB2; TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 [KO:K04404]
100454379  IL1B; interleukin-1 beta [KO:K04519]
100435461  CCL5; C-C motif chemokine 5 [KO:K12499]
100453941  IL6; interleukin-6 isoform X2 [KO:K05405]
100447558  TNF; tumor necrosis factor [KO:K03156]
100444807  IL12A; interleukin-12 subunit alpha [KO:K05406]
100435254  IL12B; interleukin-12 subunit beta [KO:K05425]
100443290  DDX58; probable ATP-dependent RNA helicase DDX58 isoform X1 [KO:K12646] [EC:5.6.2.6]
100438807  IFIH1; interferon-induced helicase C domain-containing protein 1 [KO:K12647] [EC:5.6.2.6]
100432985  MAVS; mitochondrial antiviral-signaling protein isoform X1 [KO:K12648]
100460079  TRAF3; TNF receptor-associated factor 3 isoform X1 [KO:K03174]
100448480  IKBKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [KO:K07211] [EC:2.7.11.10]
100433568  TBK1; serine/threonine-protein kinase TBK1 isoform X1 [KO:K05410] [EC:2.7.11.10]
100459543  interferon alpha-10 [KO:K05414]
100432532  IFNA8; interferon alpha-8 [KO:K05414]
100432906  IFNA2; interferon alpha-2 [KO:K05414]
100434036  IFNA6; interferon alpha-6 [KO:K05414]
100434796  interferon alpha-5 [KO:K05414]
100435169  interferon alpha-14 [KO:K05414]
100438871  interferon alpha-17-like [KO:K05414]
100439978  IFNA21; interferon alpha-21 [KO:K05414]
100432153  interferon alpha-1/13 [KO:K05414]
100445711  interferon alpha-10-like [KO:K05414]
100438149  interferon alpha-4-like [KO:K05414]
100437034  interferon alpha-4-like [KO:K05414]
100433301  interferon alpha-1/13-like [KO:K05414]
112134962  interferon alpha-10-like [KO:K05414]
100443523  interferon alpha-4-like [KO:K05414]
100456001  CGAS; cyclic GMP-AMP synthase isoform X1 [KO:K17834] [EC:2.7.7.86]
100459760  TMEM173; stimulator of interferon genes protein [KO:K12654]
100173410  PPP1CB; serine/threonine-protein phosphatase PP1-beta catalytic subunit [KO:K06269] [EC:3.1.3.16]
100459799  PPP1CA; serine/threonine-protein phosphatase PP1-alpha catalytic subunit [KO:K06269] [EC:3.1.3.16]
100458223  PPP1CC; serine/threonine-protein phosphatase PP1-gamma catalytic subunit [KO:K06269] [EC:3.1.3.16]
100440695  EIF2AK1; eukaryotic translation initiation factor 2-alpha kinase 1 isoform X1 [KO:K16194] [EC:2.7.11.1]
100173054  EIF2AK2; interferon-induced, double-stranded RNA-activated protein kinase isoform X1 [KO:K16195] [EC:2.7.11.1]
100447385  EIF2AK3; eukaryotic translation initiation factor 2-alpha kinase 3 [KO:K08860] [EC:2.7.11.1]
100457992  EIF2AK4; eIF-2-alpha kinase GCN2 isoform X1 [KO:K16196] [EC:2.7.11.1]
100174029  EIF2S1; eukaryotic translation initiation factor 2 subunit 1 [KO:K03237]
100172592  EIF2B1; translation initiation factor eIF-2B subunit alpha [KO:K03239]
100461180  EIF2B2; translation initiation factor eIF-2B subunit beta isoform X1 [KO:K03754]
100433094  EIF2B3; translation initiation factor eIF-2B subunit gamma [KO:K03241]
100441987  EIF2B4; translation initiation factor eIF-2B subunit delta isoform X1 [KO:K03680]
100446186  EIF2B5; translation initiation factor eIF-2B subunit epsilon [KO:K03240]
100443561  OAS3; 2'-5'-oligoadenylate synthase 3 isoform X2 [KO:K14216] [EC:2.7.7.84]
100444286  OAS2; 2'-5'-oligoadenylate synthase 2 [KO:K14216] [EC:2.7.7.84]
100172992  OAS1; 2'-5'-oligoadenylate synthase 1 [KO:K14216] [EC:2.7.7.84]
100174437  RNASEL; 2-5A-dependent ribonuclease [KO:K01165]
100436774  HCFC1; host cell factor 1 isoform X4 [KO:K14966]
100453490  HCFC2; host cell factor 2 isoform X1 [KO:K27390]
100433059  POU2F3; POU domain, class 2, transcription factor 3 isoform X1 [KO:K09364]
100458839  POU2F1; POU domain, class 2, transcription factor 1 isoform X1 [KO:K09364]
103888612  POU2F2; POU domain, class 2, transcription factor 2 isoform X1 [KO:K09364]
100443118  IFNAR1; interferon alpha/beta receptor 1 [KO:K05130]
100441293  IFNAR2; interferon alpha/beta receptor 2 isoform X1 [KO:K05131]
100446544  SOCS3; suppressor of cytokine signaling 3 [KO:K04696]
100433477  JAK1; tyrosine-protein kinase JAK1 isoform X1 [KO:K11217] [EC:2.7.10.2]
100439493  TYK2; LOW QUALITY PROTEIN: non-receptor tyrosine-protein kinase TYK2 [KO:K11219] [EC:2.7.10.2]
100173683  STAT1; signal transducer and activator of transcription 1-alpha/beta [KO:K11220]
100452011  STAT2; signal transducer and activator of transcription 2 isoform X3 [KO:K11221]
100455089  IRF9; interferon regulatory factor 9 [KO:K04693]
100172242  ZFP1; zinc finger protein 1 homolog [KO:K09228]
100172306  ZNF2; zinc finger protein 2 [KO:K09228]
100172320  ZNF7; zinc finger protein 7 [KO:K09228]
100172351  ZNF443; zinc finger protein 443 [KO:K09228]
100172366  ZNF549; zinc finger protein 549 [KO:K09228]
100172417  ZNF133; zinc finger protein 133 [KO:K09228]
100172509  ZNF620; zinc finger protein 620 [KO:K09228]
100172511  ZNF585B; zinc finger protein 585B [KO:K09228]
100172728  ZNF25; zinc finger protein 25 [KO:K09228]
100172784  ZNF180; zinc finger protein 180 [KO:K09228]
100172805  ZNF182; zinc finger protein 182 [KO:K09228]
100431746  ZNF74; zinc finger protein 74 [KO:K09228]
100432240  ZFP57; zinc finger protein 57 homolog [KO:K09228]
100432361  ZNF283; zinc finger protein 283 isoform X1 [KO:K09228]
100432643  ZNF250; LOW QUALITY PROTEIN: zinc finger protein 250 [KO:K09228]
100432931  ZNF268; zinc finger protein 268 isoform X1 [KO:K09228]
100439202  ZNF300; zinc finger protein 300 isoform X1 [KO:K09228]
100439924  zinc finger protein 429 [KO:K09228]
100440425  ZNF490; zinc finger protein 490 isoform X1 [KO:K09228]
100440482  ZFP14; zinc finger protein 14 homolog isoform X1 [KO:K09228]
100440660  ZNF229; zinc finger protein 229 isoform X1 [KO:K09228]
100440915  ZNF584; zinc finger protein 584 isoform X1 [KO:K09228]
100441283  ZNF667; zinc finger protein 667 [KO:K09228]
100442132  ZNF558; zinc finger protein 558 [KO:K09228]
100442196  ZNF175; zinc finger protein 175 isoform X1 [KO:K09228]
100442553  zinc finger protein 267 isoform X1 [KO:K09228]
100442659  ZNF596; zinc finger protein 596 isoform X1 [KO:K09228]
100442743  ZNF546; zinc finger protein 546 [KO:K09228]
100443599  ZNF257; zinc finger protein 257 [KO:K09228]
100433040  ZNF79; zinc finger protein 79 isoform X1 [KO:K09228]
100433124  ZNF45; zinc finger protein 45 isoform X1 [KO:K09228]
100433402  RB-associated KRAB zinc finger protein isoform X1 [KO:K09228]
100433614  ZNF135; zinc finger protein 135 isoform X3 [KO:K09228]
100433689  ZNF124; zinc finger protein 124 isoform X1 [KO:K09228]
100433721  protein ZNF738 [KO:K09228]
100433726  ZNF221; zinc finger protein 221 [KO:K09228]
100433802  ZNF195; zinc finger protein 195 isoform X1 [KO:K09228]
100434041  ZNF189; zinc finger protein 189 isoform X1 [KO:K09228]
100434122  ZNF674; zinc finger protein 674 isoform X1 [KO:K09228]
100434452  ZNF670; zinc finger protein 670 [KO:K09228]
100434632  ZNF155; zinc finger protein 155 isoform X1 [KO:K09228]
100434739  LOW QUALITY PROTEIN: zinc finger protein 287 [KO:K09228]
100434861  zinc finger protein 570 isoform X1 [KO:K09228]
100435063  ZNF641; zinc finger protein 641 isoform X2 [KO:K09228]
100435741  ZNF284; zinc finger protein 284 [KO:K09228]
100435819  ZNF514; zinc finger protein 514 [KO:K09228]
100436015  ZNF736; zinc finger protein 736 isoform X1 [KO:K09228]
100436044  ZNF248; zinc finger protein 248 [KO:K09228]
100437875  ZNF81; zinc finger protein 81 [KO:K09228]
100437913  ZFP37; zinc finger protein 37 homolog isoform X1 [KO:K09228]
100437956  ZNF200; zinc finger protein 200 [KO:K09228]
100438285  ZNF707; zinc finger protein 707 isoform X2 [KO:K09228]
100438341  zinc finger protein 563 isoform X1 [KO:K09228]
100438581  ZNF233; LOW QUALITY PROTEIN: zinc finger protein 233 [KO:K09228]
100438759  ZNF782; zinc finger protein 782 [KO:K09228]
100438952  ZNF112; zinc finger protein 112 [KO:K09228]
100446182  ZNF619; zinc finger protein 619 isoform X1 [KO:K09228]
100446287  ZNF286A; zinc finger protein 286A isoform X3 [KO:K09228]
100447072  zinc finger protein 479-like [KO:K09228]
100447284  LOW QUALITY PROTEIN: zinc finger protein 726 [KO:K09228]
100447806  ZNF12; zinc finger protein 12 [KO:K09228]
100448749  LOW QUALITY PROTEIN: protein ZNF738-like [KO:K09228]
100448916  ZNF786; zinc finger protein 786 isoform X1 [KO:K09228]
100449010  zinc finger protein 718 [KO:K09228]
100449012  ZNF613; zinc finger protein 613 isoform X1 [KO:K09228]
100449594  zinc finger protein 141 isoform X1 [KO:K09228]
100449714  ZNF177; zinc finger protein 177 isoform X1 [KO:K09228]
100449948  ZNF721; zinc finger protein 721 isoform X1 [KO:K09228]
100450206  ZNF132; zinc finger protein 132 [KO:K09228]
100450439  ZNF557; zinc finger protein 557 isoform X2 [KO:K09228]
100450452  ZIM3; zinc finger imprinted 3 [KO:K09228]
100172169  ZNF614; zinc finger protein 614 [KO:K09228]
100460025  zinc finger protein 273 isoform X2 [KO:K09228]
100460305  ZNF605; zinc finger protein 605 isoform X1 [KO:K09228]
100460403  ZNF251; zinc finger protein 251 isoform X3 [KO:K09228]
100460411  LOW QUALITY PROTEIN: zinc finger protein 93 [KO:K09228]
100460480  ZNF154; zinc finger protein 154 [KO:K09228]
100460572  ZFP90; zinc finger protein 90 homolog isoform X1 [KO:K09228]
100460716  ZNF568; zinc finger protein 568 isoform X1 [KO:K09228]
100461078  ZNF433; zinc finger protein 433 isoform X1 [KO:K09228]
100461456  LOW QUALITY PROTEIN: zinc finger protein 611 [KO:K09228]
100461639  ZNF34; zinc finger protein 34 isoform X1 [KO:K09228]
100462187  ZNF383; zinc finger protein 383 [KO:K09228]
100462377  ZNF227; zinc finger protein 227 isoform X1 [KO:K09228]
100172885  ZNF14; zinc finger protein 14 [KO:K09228]
100173223  HKR1; Krueppel-related zinc finger protein 1 isoform 2 [KO:K09228]
100173308  ZNF19; zinc finger protein 19 [KO:K09228]
100173355  ZNF382; zinc finger protein 382 [KO:K09228]
100173652  ZNF436; zinc finger protein 436 [KO:K09228]
100173710  ZNF571; zinc finger protein 571 [KO:K09228]
100174050  ZNF41; zinc finger protein 41 [KO:K09228]
100174242  ZNF561; zinc finger protein 561 [KO:K09228]
100174255  ZNF791; zinc finger protein 791 [KO:K09228]
100174427  ZNF226; zinc finger protein 226 [KO:K09228]
100174450  ZNF235; zinc finger protein 235 [KO:K09228]
100174608  ZNF84; zinc finger protein 84 [KO:K09228]
100174680  ZNF540; zinc finger protein 540 [KO:K09228]
100189657  ZNF317; zinc finger protein 317 [KO:K09228]
100189844  ZNF615; zinc finger protein 615 [KO:K09228]
100294569  ZNF8; zinc finger protein 8 [KO:K09228]
100437248  zinc finger protein 44 isoform X1 [KO:K09228]
100456548  ZNF624; zinc finger protein 624 isoform X1 [KO:K09228]
100456811  ZNF211; zinc finger protein 211 isoform X2 [KO:K09228]
100456989  ZNF484; zinc finger protein 484 isoform X1 [KO:K09228]
100457052  ZNF528; zinc finger protein 528 isoform X1 [KO:K09228]
100457555  ZNF790; zinc finger protein 790 isoform X1 [KO:K09228]
100457774  ZNF57; zinc finger protein 57 [KO:K09228]
100457843  ZNF169; zinc finger protein 169 [KO:K09228]
100458136  ZNF77; zinc finger protein 77 [KO:K09228]
100458630  ZNF829; zinc finger protein 829 [KO:K09228]
100459233  ZNF627; zinc finger protein 627 isoform X1 [KO:K09228]
100459358  ZNF420; zinc finger protein 420 [KO:K09228]
100459366  ZNF671; zinc finger protein 671 isoform X1 [KO:K09228]
100459608  ZNF823; zinc finger protein 823 [KO:K09228]
100459612  ZNF101; zinc finger protein 101 isoform X1 [KO:K09228]
100450566  LOW QUALITY PROTEIN: zinc finger protein 724-like [KO:K09228]
100450851  ZNF398; zinc finger protein 398 [KO:K09228]
100451054  ZNF473; zinc finger protein 473 [KO:K09228]
100451177  ZNF599; zinc finger protein 599 isoform X2 [KO:K09228]
100451431  ZNF836; zinc finger protein 836 isoform X2 [KO:K09228]
100452112  zinc finger protein 486 isoform X4 [KO:K09228]
100452307  ZNF343; zinc finger protein 343 isoform X1 [KO:K09228]
100452347  ZNF212; zinc finger protein 212 isoform X1 [KO:K09228]
100452682  ZNF337; zinc finger protein 337 [KO:K09228]
100452928  zinc finger protein 883 isoform X1 [KO:K09228]
100453185  ZNF543; zinc finger protein 543 [KO:K09228]
100453550  ZNF304; zinc finger protein 304 isoform X1 [KO:K09228]
100454068  ZNF713; zinc finger protein 713 isoform X3 [KO:K09228]
100454256  ZNF688; zinc finger protein 688 [KO:K09228]
100454506  ZNF560; zinc finger protein 560 [KO:K09228]
100454514  ZNF461; zinc finger protein 461 isoform X1 [KO:K09228]
100454624  ZNF689; zinc finger protein 689 [KO:K09228]
100454655  zinc finger protein 419 isoform X1 [KO:K09228]
100455232  ZNF426; zinc finger protein 426 isoform X1 [KO:K09228]
100455289  ZNF777; zinc finger protein 777 isoform X1 [KO:K09228]
100455658  ZNF746; zinc finger protein 746 isoform X1 [KO:K09228]
100455742  ZNF766; zinc finger protein 766 [KO:K09228]
100444718  ZNF311; zinc finger protein 311 [KO:K09228]
100444748  ZNF658; zinc finger protein 658 isoform X1 [KO:K09228]
100444860  ZNF519; zinc finger protein 519 [KO:K09228]
100445555  ZNF354A; zinc finger protein 354A isoform X1 [KO:K09228]
100445935  ZFP28; zinc finger protein 28 homolog [KO:K09228]
100171560  ZNF23; zinc finger protein 23 [KO:K09228]
100171641  ZNF334; zinc finger protein 334 [KO:K09228]
100171692  ZNF136; zinc finger protein 136 [KO:K09228]
100171759  ZNF331; zinc finger protein 331 [KO:K09228]
100171832  ZNF214; zinc finger protein 214 [KO:K09228]
100171843  ZNF585A; zinc finger protein 585A [KO:K09228]
100172077  ZNF547; zinc finger protein 547 [KO:K09228]
100172086  ZNF566; zinc finger protein 566 [KO:K09228]
100431978  ZNF846; LOW QUALITY PROTEIN: zinc finger protein 846 [KO:K09228]
100432844  ZNF662; zinc finger protein 662 isoform X2 [KO:K09228]
100451606  ZNF282; zinc finger protein 282 [KO:K09228]
100431257  ZNF275; zinc finger protein 275 [KO:K09228]
100462078  zinc finger protein 813 [KO:K09228]
100171648  ZNF813; zinc finger protein 813 [KO:K09228]
100436539  zinc finger protein 765 isoform X1 [KO:K09228]
100189761  ZNF302; zinc finger protein 302 [KO:K09228]
100446243  LOW QUALITY PROTEIN: zinc finger protein 91 [KO:K09228]
100437909  ZNF623; zinc finger protein 623 [KO:K09228]
100436404  ZNF679; zinc finger protein 679 [KO:K09228]
100452786  zinc finger protein 764 isoform X4 [KO:K09228]
100434603  ZFP69B; zinc finger protein ZFP69B isoform X2 [KO:K09228]
100171725  ZNF181; zinc finger protein 181 [KO:K09228]
100172988  ZNF665; zinc finger protein 665 [KO:K09228]
100459001  ZNF551; zinc finger protein 551 [KO:K09228]
100461410  ZNF140; zinc finger protein 140 isoform X1 [KO:K09228]
100442745  zinc finger protein 766 isoform X1 [KO:K09228]
100434997  ZNF625; zinc finger protein 625 isoform X1 [KO:K09228]
100435150  zinc finger protein 679 [KO:K09228]
100435368  ZNF878; zinc finger protein 878 [KO:K09228]
100441248  ZSCAN32; zinc finger and SCAN domain-containing protein 32 isoform X1 [KO:K09228]
100444697  ZNF550; zinc finger protein 550 [KO:K09228]
100450313  ZNF559; zinc finger protein 559 isoform X1 [KO:K09228]
100450448  ZNF565; zinc finger protein 565 [KO:K09228]
100451461  zinc finger protein 479-like [KO:K09228]
100454652  ZNF577; zinc finger protein 577 isoform X1 [KO:K09228]
100457668  zinc finger protein 562 isoform X1 [KO:K09228]
100458146  LOW QUALITY PROTEIN: zinc finger protein 534 [KO:K09228]
100461459  ZNF552; LOW QUALITY PROTEIN: zinc finger protein 552 [KO:K09228]
100461687  ZNF778; zinc finger protein 778 [KO:K09228]
100436784  ZNF735; putative zinc finger protein 735 [KO:K09228]
100441977  ZNF597; zinc finger protein 597 [KO:K09228]
100444335  zinc finger protein 17 isoform X1 [KO:K09228]
100444690  LOW QUALITY PROTEIN: zinc finger protein 729 [KO:K09228]
100448046  LOW QUALITY PROTEIN: putative uncharacterized zinc finger protein 814 [KO:K09228]
100443962  zinc finger protein 676 isoform X1 [KO:K09228]
100432724  ZNF527; zinc finger protein 527 isoform X1 [KO:K09228]
100436434  ZNF33A; LOW QUALITY PROTEIN: zinc finger protein 33A [KO:K09228]
100439379  ZNF510; zinc finger protein 510 isoform X1 [KO:K09228]
100439950  ZNF630; LOW QUALITY PROTEIN: zinc finger protein 630 [KO:K09228]
100448553  ZNF316; zinc finger protein 316 [KO:K09228]
100449757  ZNF425; zinc finger protein 425 [KO:K09228]
100452724  ZNF783; protein ZNF783 [KO:K09228]
100453656  zinc finger protein 780A isoform X1 [KO:K09228]
100457428  ZNF610; zinc finger protein 610 [KO:K09228]
100937326  ZFP92; zinc finger protein 92 homolog [KO:K09228]
100455738  ZNF850; zinc finger protein 850 [KO:K09228]
100173003  ZNF717; zinc finger protein 717 [KO:K09228]
100438994  ZNF680; zinc finger protein 680 isoform X1 [KO:K09228]
103888703  ZNF583; zinc finger protein 583 isoform X1 [KO:K09228]
103888736  ZNF544; zinc finger protein 544 isoform X1 [KO:K09228]
103888678  ZNF160; zinc finger protein 160 isoform X1 [KO:K09228]
103888598  ZNF607; zinc finger protein 607 isoform X1 [KO:K09228]
103892174  ZNF26; zinc finger protein 26 isoform X1 [KO:K09228]
103891419  LOW QUALITY PROTEIN: zinc finger protein 252-like [KO:K09228]
103888680  ZNF347; zinc finger protein 347 isoform X1 [KO:K09228]
100432484  ZNF418; zinc finger protein 418 isoform X1 [KO:K09228]
103892176  ZNF10; zinc finger protein 10 [KO:K09228]
103893061  zinc finger protein 709 [KO:K09228]
103888597  ZFP30; zinc finger protein 30 homolog isoform X3 [KO:K09228]
103888685  zinc finger protein 845 [KO:K09228]
103888677  ZNF816; zinc finger protein 816 [KO:K09228]
103888699  ZNF582; zinc finger protein 582 isoform X2 [KO:K09228]
103888505  ZNF529; zinc finger protein 529 [KO:K09228]
100452052  zinc finger protein 91-like [KO:K09228]
100451315  ZNF595; zinc finger protein 595 isoform X1 [KO:K09228]
100437553  zinc finger protein 37A isoform X1 [KO:K09228]
103890845  ZNF184; zinc finger protein 184 isoform X1 [KO:K09228]
100455374  ZNF567; zinc finger protein 567 isoform X1 [KO:K09228]
103890785  ZNF879; zinc finger protein 879 [KO:K09228]
103888659  ZNF432; zinc finger protein 432 isoform X1 [KO:K09228]
103888704  ZNF471; zinc finger protein 471 [KO:K09228]
103888708  ZNF470; zinc finger protein 470 [KO:K09228]
103888723  ZNF606; zinc finger protein 606 isoform X1 [KO:K09228]
103888662  ZNF616; zinc finger protein 616 [KO:K09228]
100437891  putative zinc finger protein 727 [KO:K09228]
100940286  ZNF649; zinc finger protein 649 isoform X1 [KO:K09228]
100938168  ZNF404; zinc finger protein 404 [KO:K09228]
100462443  zinc finger protein 600 [KO:K09228]
100435842  LOW QUALITY PROTEIN: zinc finger protein 431 [KO:K09228]
100433361  zinc finger protein 433-like isoform X1 [KO:K09228]
103893083  zinc finger protein 506 isoform X1 [KO:K09228]
100939702  ZNF350; zinc finger protein 350 isoform X1 [KO:K09228]
103888718  ZIK1; zinc finger protein interacting with ribonucleoprotein K isoform X4 [KO:K09228]
103889655  ZNF682; zinc finger protein 682 [KO:K09228]
100458992  LOW QUALITY PROTEIN: zinc finger protein 568-like [KO:K09228]
100442137  zinc finger protein 43-like [KO:K09228]
103888722  ZNF256; zinc finger protein 256 isoform X1 [KO:K09228]
103893093  LOW QUALITY PROTEIN: zinc finger protein 675 [KO:K09228]
103888632  ZNF224; zinc finger protein 224 [KO:K09228]
103888733  ZNF530; zinc finger protein 530 [KO:K09228]
103888664  ZNF480; zinc finger protein 480 isoform X1 [KO:K09228]
103888679  ZNF415; zinc finger protein 415 isoform X1 [KO:K09228]
100445947  ZNF354B; zinc finger protein 354B [KO:K09228]
103888588  ZFP82; zinc finger protein 82 homolog isoform X3 [KO:K09228]
103888629  ZNF234; zinc finger protein 234 [KO:K09228]
103890786  ZNF354C; zinc finger protein 354C [KO:K09228]
103888721  zinc finger protein 417 isoform X1 [KO:K09228]
100448036  zinc finger protein 99 [KO:K09228]
100443242  ZNF264; zinc finger protein 264 isoform X1 [KO:K09228]
103888630  ZNF225; zinc finger protein 225 isoform X1 [KO:K09228]
103893056  zinc finger protein 20 isoform X1 [KO:K09228]
103888700  zinc finger protein OZF-like isoform X1 [KO:K09228]
103893050  zinc finger protein 700 [KO:K09228]
103888713  ZNF460; zinc finger protein 460 [KO:K09228]
103889425  zinc finger protein 501-like [KO:K09228]
103893060  LOW QUALITY PROTEIN: zinc finger protein 442 [KO:K09228]
103890790  ZNF454; zinc finger protein 454 [KO:K09228]
100433765  ZNF107; zinc finger protein 107 isoform X3 [KO:K09228]
100441524  zinc finger protein 799 isoform X1 [KO:K09228]
103893059  LOW QUALITY PROTEIN: zinc finger protein 788-like [KO:K09228]
103888715  LOW QUALITY PROTEIN: zinc finger protein 773 [KO:K09228]
103892868  ZFP69; zinc finger protein ZFP69 isoform X1 [KO:K09228]
103888731  ZNF324; zinc finger protein 324A isoform X1 [KO:K09228]
103888730  ZNF324B; zinc finger protein 324B [KO:K09228]
103888628  zinc finger protein 222 [KO:K09228]
103892175  ZNF891; zinc finger protein 891 [KO:K09228]
103891416  ZNF517; LOW QUALITY PROTEIN: zinc finger protein 517 [KO:K09228]
100443295  zinc finger protein 564 isoform X1 [KO:K09228]
100436363  ZNF223; zinc finger protein 223 isoform X1 [KO:K09228]
103891101  putative zinc finger protein 735 [KO:K09228]
100458385  LOW QUALITY PROTEIN: putative zinc finger protein 812 [KO:K09228]
100435211  ZNF205; zinc finger protein 205 isoform X1 [KO:K09228]
100457418  ZNF556; zinc finger protein 556 [KO:K09228]
103892656  ZNF764; zinc finger protein 764 isoform X1 [KO:K09228]
103892655  ZNF785; zinc finger protein 785 [KO:K09228]
100434864  ZNF114; zinc finger protein 114 isoform X3 [KO:K09228]
100437620  ZNF793; zinc finger protein 793 [KO:K09228]
100455737  ZNF726; zinc finger protein 726 [KO:K09228]
100172044  ZNF333; zinc finger protein 333 [KO:K09228]
100438155  LOW QUALITY PROTEIN: zinc finger protein 701-like [KO:K09228]
100451044  ZNF266; zinc finger protein 266 [KO:K09228]
100938707  zinc finger protein 28 isoform X1 [KO:K09228]
100434249  ZNF569; zinc finger protein 569 [KO:K09228]
100439248  LOW QUALITY PROTEIN: zinc finger protein 285-like [KO:K09228]
100440486  LOW QUALITY PROTEIN: zinc finger protein 33B-like [KO:K09228]
100453230  ZNF792; zinc finger protein 792 isoform X1 [KO:K09228]
100456331  ZNF555; zinc finger protein 555 isoform X2 [KO:K09228]
100458450  LOW QUALITY PROTEIN: zinc finger protein 717-like [KO:K09228]
100936545  ZNF780B; zinc finger protein 780B isoform X1 [KO:K09228]
100936577  ZNF30; zinc finger protein 30 isoform X1 [KO:K09228]
100936788  LOW QUALITY PROTEIN: zinc finger protein 83-like [KO:K09228]
100937597  ZNF677; zinc finger protein 677 [KO:K09228]
103888661  ZNF841; zinc finger protein 841 [KO:K09228]
103888717  ZNF416; zinc finger protein 416 [KO:K09228]
103890207  ZNF621; zinc finger protein 621 isoform X1 [KO:K09228]
103893032  ZNF699; zinc finger protein 699 isoform X2 [KO:K09228]
103893054  LOW QUALITY PROTEIN: zinc finger protein 763 [KO:K09228]
103893095  zinc finger protein 254 isoform X1 [KO:K09228]
112130082  ZNF749; zinc finger protein 749 isoform X1 [KO:K09228]
112130083  ZNF772; zinc finger protein 772 isoform X1 [KO:K09228]
112130111  ZNF554; zinc finger protein 554 isoform X1 [KO:K09228]
112130923  ZNF157; zinc finger protein 157 [KO:K09228]
112131818  LOW QUALITY PROTEIN: zinc finger protein 430-like [KO:K09228]
112134293  ZNF669; zinc finger protein 669 [KO:K09228]
112134341  ZNF853; zinc finger protein 853 isoform X1 [KO:K09228]
100462229  LOW QUALITY PROTEIN: zinc finger protein 117-like [KO:K09228]
100451404  LOW QUALITY PROTEIN: zinc finger protein 724-like [KO:K09228]
100447016  LOW QUALITY PROTEIN: putative zinc finger protein 727 [KO:K09228]
100432405  LOW QUALITY PROTEIN: zinc finger protein 705A-like [KO:K09228]
103888547  LOW QUALITY PROTEIN: zinc finger protein 737 [KO:K09228]
100294610  ZNF439; zinc finger protein 439 [KO:K09228]
100453616  ZNF678; LOW QUALITY PROTEIN: zinc finger protein 678 [KO:K09228]
100445109  ZNF880; zinc finger protein 880 [KO:K09228]
100434499  LOW QUALITY PROTEIN: zinc finger protein 28 [KO:K09228]
103888712  ZNF805; zinc finger protein 805 isoform X1 [KO:K09228]
100462196  ZNF776; zinc finger protein 776 [KO:K09228]
103888726  ZNF497; zinc finger protein 497 [KO:K09228]
100436735  ZNF573; zinc finger protein 573 isoform X1 [KO:K09228]
100445047  zinc finger protein 492 isoform X2 [KO:K09228]
100434624  zinc finger protein 709 [KO:K09228]
103891618  zinc finger protein 501-like [KO:K09228]
100434826  ZNF695; zinc finger protein 695 isoform X1 [KO:K09228]
100432935  zinc finger protein 682-like isoform X1 [KO:K09228]
103893053  ZNF441; zinc finger protein 441 [KO:K09228]
100459151  zinc finger protein 92 [KO:K09228]
100445959  zinc finger protein 479 isoform X1 [KO:K09228]
100447721  ZNF485; zinc finger protein 485 isoform X1 [KO:K09228]
112130069  zinc finger protein 587-like isoform X1 [KO:K09228]
112130090  zinc finger protein 160-like [KO:K09228]
112130095  LOW QUALITY PROTEIN: zinc finger protein 709-like [KO:K09228]
100937489  zinc finger protein 430 isoform X1 [KO:K09228]
100449526  LOW QUALITY PROTEIN: zinc finger protein 626-like [KO:K09228]
100461269  zinc finger protein 737 [KO:K09228]
100936299  ZNF208; zinc finger protein 208 isoform X1 [KO:K09228]
100454278  ZNF681; zinc finger protein 681 [KO:K09228]
103893049  LOW QUALITY PROTEIN: zinc finger protein 439-like [KO:K09228]
100455373  zinc finger protein 254-like [KO:K09228]
100459243  LOW QUALITY PROTEIN: zinc finger protein 578 [KO:K09228]
103888668  ZNF808; zinc finger protein 808 isoform X1 [KO:K09228]
100434681  zinc finger protein 160-like [KO:K09228]
100443108  LOW QUALITY PROTEIN: zinc finger protein 813-like [KO:K09228]
100444211  zinc finger protein 761 [KO:K09228]
100433363  zinc finger protein 737 [KO:K09228]
100431789  zinc finger protein 737-like [KO:K09228]
100445798  LOW QUALITY PROTEIN: zinc finger protein 675-like [KO:K09228]
103888572  zinc finger protein 709-like [KO:K09228]
100458501  LOW QUALITY PROTEIN: zinc finger protein 717 [KO:K09228]
112132694  ZNF860; LOW QUALITY PROTEIN: zinc finger protein 860 [KO:K09228]
100453178  LOW QUALITY PROTEIN: zinc finger protein 732 [KO:K09228]
112132776  ZNF502; zinc finger protein 502 [KO:K09228]
100436518  zinc finger protein 33A-like [KO:K09228]
100450477  LOW QUALITY PROTEIN: zinc finger protein 33B-like [KO:K09228]
112135131  LOW QUALITY PROTEIN: zinc finger protein 239-like [KO:K09228]
103888720  zinc finger protein 586 isoform X7 [KO:K09228]
100359386  BST2; bone marrow stromal antigen 2 [KO:K06731]
100444043  IFNG; interferon gamma [KO:K04687]
100171593  IFNGR1; interferon gamma receptor 1 precursor [KO:K05132]
100442383  IFNGR2; interferon gamma receptor 2 [KO:K05133]
100172517  JAK2; tyrosine-protein kinase JAK2 [KO:K04447] [EC:2.7.10.2]
100433571  DAXX; death domain-associated protein 6 isoform X1 [KO:K02308]
100171661  SP100; nuclear autoantigen Sp-100 [KO:K15413]
100445630  PML; LOW QUALITY PROTEIN: protein PML [KO:K10054] [EC:2.3.2.-]
100444044  TAP1; antigen peptide transporter 1 isoform X1 [KO:K05653] [EC:7.4.2.14]
100444404  TAP2; antigen peptide transporter 2 [KO:K05654] [EC:7.4.2.14]
100431428  TAPBP; tapasin isoform X2 [KO:K08058]
100174305  PDIA3; protein disulfide-isomerase A3 precursor [KO:K08056] [EC:5.3.4.1]
100451803  CALR; calreticulin [KO:K08057]
100173719  DKFZP469M1914; major histocompatibility complex, class I, C precursor [KO:K06751]
100189734  DKFZP469I0912 protein isoform X1 [KO:K06751]
100432875  HLA class I histocompatibility antigen, alpha chain F isoform X1 [KO:K06751]
100456603  LOW QUALITY PROTEIN: patr class I histocompatibility antigen, A-126 alpha chain-like [KO:K06751]
100440558  popy class I histocompatibility antigen, alpha chain E isoform X3 [KO:K06751]
100438533  patr class I histocompatibility antigen, B-2 alpha chain isoform X1 [KO:K06751]
100435866  popy Class I histocompatibility antigen, A-1 alpha chain [KO:K06751]
100450716  HLA class I histocompatibility antigen, alpha chain G isoform X1 [KO:K06751]
100452132  class I histocompatibility antigen, Gogo-B*0102 alpha chain isoform X1 [KO:K06751]
100435133  saoe class I histocompatibility antigen, A alpha chain-like [KO:K06751]
100449631  LOW QUALITY PROTEIN: patr class I histocompatibility antigen, A-126 alpha chain-like [KO:K06751]
100174579  B2M; beta-2-microglobulin isoform X1 [KO:K08055]
100458290  HLA class II histocompatibility antigen, DO alpha chain [KO:K06752]
100453254  HLA class II histocompatibility antigen, DRB1-11 beta chain isoform X1 [KO:K06752]
100443317  HLA class II histocompatibility antigen, DQ alpha 2 chain [KO:K06752]
100442956  HLA class II histocompatibility antigen, DQ alpha 2 chain [KO:K06752]
100442586  HLA class II histocompatibility antigen, DQ beta 2 chain isoform X1 [KO:K06752]
100443682  HLA class II histocompatibility antigen, DO beta chain [KO:K06752]
100448477  HLA class II histocompatibility antigen, DM beta chain [KO:K06752]
100448112  HLA class II histocompatibility antigen, DM alpha chain isoform X1 [KO:K06752]
100460187  HLA class II histocompatibility antigen, DR alpha chain [KO:K06752]
100438181  HLA class II histocompatibility antigen, DP alpha 1 chain [KO:K06752]
100444477  HLA class II histocompatibility antigen, DP beta 1 chain isoform X1 [KO:K06752]
100456477  HLA class II histocompatibility antigen, DR beta 5 chain isoform X1 [KO:K06752]
100457574  HLA class II histocompatibility antigen, DQ beta 1 chain isoform X3 [KO:K06752]
100456830  HLA class II histocompatibility antigen, DR beta 4 chain-like [KO:K06752]
100443747  HLA class II histocompatibility antigen, DRB1-9 beta chain isoform X1 [KO:K06752]
100442225  HLA class II histocompatibility antigen, DRB1-4 beta chain isoform X1 [KO:K06752]
100449199  LOW QUALITY PROTEIN: RLA class II histocompatibility antigen, DP alpha-1 chain-like [KO:K06752]
100171468  CD74; CD74 molecule [KO:K06505]
100432846  PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
100453779  PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
103889133  PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
100174298  PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma [KO:K02649]
100173589  PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha [KO:K02649]
100437617  PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta [KO:K02649]
100454279  AKT2; RAC-beta serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
100448114  AKT3; RAC-gamma serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
100442100  AKT1; RAC-alpha serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
100147742  TSC1; hamartin [KO:K07206]
100441126  TSC2; tuberin isoform X1 [KO:K07207]
100447214  RHEB; GTP-binding protein Rheb [KO:K07208]
100456786  MTOR; serine/threonine-protein kinase mTOR [KO:K07203] [EC:2.7.11.1]
100455169  EIF4EBP1; eukaryotic translation initiation factor 4E-binding protein 1 [KO:K07205]
100172042  SRPK1; SRSF protein kinase 1 [KO:K15409] [EC:2.7.11.1]
100173318  SRSF1; serine/arginine-rich splicing factor 1 [KO:K12890]
100443911  SRSF8; splicing factor, arginine/serine-rich 2B [KO:K12891]
100448817  serine/arginine-rich splicing factor 8-like isoform X1 [KO:K12891]
100439801  SRSF2; serine/arginine-rich splicing factor 2 [KO:K12891]
100453074  SRSF3; serine/arginine-rich splicing factor 3 [KO:K12892]
100458472  SRSF5; serine/arginine-rich splicing factor 5 [KO:K12893]
100455023  SRSF6; serine/arginine-rich splicing factor 6 [KO:K12893]
100454854  SRSF4; serine/arginine-rich splicing factor 4 isoform X1 [KO:K12893]
100460575  SRSF7; serine/arginine-rich splicing factor 7 [KO:K12896]
100454840  SRSF9; serine/arginine-rich splicing factor 9 [KO:K21123]
100452633  serine/arginine-rich splicing factor 9-like [KO:K21123]
100454300  nuclear RNA export factor 2 [KO:K14284]
100460986  NXF3; nuclear RNA export factor 3 [KO:K14284]
100449073  NXF1; nuclear RNA export factor 1 isoform X1 [KO:K14284]
100451207  NXF5; LOW QUALITY PROTEIN: nuclear RNA export factor 5 [KO:K14284]
100437514  LOW QUALITY PROTEIN: nuclear RNA export factor 2-like [KO:K14284]
100450309  ALYREF; THO complex subunit 4 [KO:K12881]
100461418  FASLG; tumor necrosis factor ligand superfamily member 6 isoform X1 [KO:K04389]
100438667  TNFRSF1A; tumor necrosis factor receptor superfamily member 1A [KO:K03158]
100442719  TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein isoform X1 [KO:K03171]
100439256  FADD; FAS-associated death domain protein [KO:K02373]
100172115  CASP8; caspase-8 [KO:K04398] [EC:3.4.22.61]
100173269  BID; BH3-interacting domain death agonist [KO:K04726]
100450682  BAX; apoptosis regulator BAX isoform X1 [KO:K02159]
100460189  bcl-2 homologous antagonist/killer [KO:K14021]
100432001  BAK1; bcl-2 homologous antagonist/killer isoform X1 [KO:K14021]
100454097  BAD; bcl2-associated agonist of cell death [KO:K02158]
100938429  BCL2; apoptosis regulator Bcl-2 isoform X1 [KO:K02161]
100453051  BCL2L1; bcl-2-like protein 1 [KO:K04570]
100171479  CYCS; cytochrome c [KO:K08738]
100462404  cytochrome c-like [KO:K08738]
112128551  cytochrome c-like [KO:K08738]
100445149  cytochrome c-like [KO:K08738]
112128607  cytochrome c-like [KO:K08738]
112130824  cytochrome c-like [KO:K08738]
112132396  LOW QUALITY PROTEIN: cytochrome c 2-like [KO:K08738]
112133797  cytochrome c-like [KO:K08738]
112134675  cytochrome c-like [KO:K08738]
112134685  cytochrome c-like [KO:K08738]
112134371  cytochrome c-like [KO:K08738]
112134960  cytochrome c-like [KO:K08738]
112135506  cytochrome c-like [KO:K08738]
100459074  APAF1; apoptotic protease-activating factor 1 [KO:K02084]
100460459  CASP9; caspase-9 isoform X1 [KO:K04399] [EC:3.4.22.62]
100435491  CASP3; caspase-3 [KO:K02187] [EC:3.4.22.56]
Compound
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C20640  Cyclic GMP-AMP
C20935  2-5A
Reference
PMID:12787566
  Authors
Granger SW, Rickert S
  Title
LIGHT-HVEM signaling and the regulation of T cell-mediated immunity.
  Journal
Cytokine Growth Factor Rev 14:289-96 (2003)
DOI:10.1016/S1359-6101(03)00031-5
Reference
PMID:19495760
  Authors
Steinberg MW, Shui JW, Ware CF, Kronenberg M
  Title
Regulating the mucosal immune system: the contrasting roles of LIGHT, HVEM, and their various partners.
  Journal
Semin Immunopathol 31:207-21 (2009)
DOI:10.1007/s00281-009-0157-4
Reference
PMID:20221426
  Authors
MacLeod IJ, Minson T
  Title
Binding of herpes simplex virus type-1 virions leads to the induction of intracellular signalling in the absence of virus entry.
  Journal
PLoS One 5:e9560 (2010)
DOI:10.1371/journal.pone.0009560
Reference
PMID:23150579
  Authors
Gianni T, Leoni V, Chesnokova LS, Hutt-Fletcher LM, Campadelli-Fiume G
  Title
alphavbeta3-integrin is a major sensor and activator of innate immunity to herpes simplex virus-1.
  Journal
Proc Natl Acad Sci U S A 109:19792-7 (2012)
DOI:10.1073/pnas.1212597109
Reference
PMID:25375272
  Authors
Gianni T, Campadelli-Fiume G
  Title
The epithelial alphavbeta3-integrin boosts the MYD88-dependent TLR2 signaling in response to viral and bacterial components.
  Journal
PLoS Pathog 10:e1004477 (2014)
DOI:10.1371/journal.ppat.1004477
Reference
PMID:15056211
  Authors
Spear PG
  Title
Herpes simplex virus: receptors and ligands for cell entry.
  Journal
Cell Microbiol 6:401-10 (2004)
DOI:10.1111/j.1462-5822.2004.00389.x
Reference
PMID:12855695
  Authors
Boutell C, Everett RD
  Title
The herpes simplex virus type 1 (HSV-1) regulatory protein ICP0 interacts with and Ubiquitinates p53.
  Journal
J Biol Chem 278:36596-602 (2003)
DOI:10.1074/jbc.M300776200
Reference
PMID:24262390
  Authors
Ma Y, He B
  Title
Recognition of herpes simplex viruses: toll-like receptors and beyond.
  Journal
J Mol Biol 426:1133-47 (2014)
DOI:10.1016/j.jmb.2013.11.012
Reference
PMID:26952111
  Authors
Su C, Zhan G, Zheng C
  Title
Evasion of host antiviral innate immunity by HSV-1, an update.
  Journal
Virol J 13:38 (2016)
DOI:10.1186/s12985-016-0495-5
Reference
PMID:21994567
  Authors
Melchjorsen J, Matikainen S, Paludan SR
  Title
Activation and evasion of innate antiviral immunity by herpes simplex virus.
  Journal
Viruses 1:737-59 (2009)
DOI:10.3390/v1030737
Reference
PMID:15276609
  Authors
Morrison LA
  Title
The Toll of herpes simplex virus infection.
  Journal
Trends Microbiol 12:353-6 (2004)
DOI:10.1016/j.tim.2004.06.001
Reference
PMID:29298887
  Authors
Zheng C
  Title
Evasion of Cytosolic DNA-Stimulated Innate Immune Responses by Herpes Simplex Virus 1.
  Journal
J Virol 92:e00099-17 (2018)
DOI:10.1128/JVI.00099-17
Reference
PMID:19344302
  Authors
Grandi P, Peruzzi P, Reinhart B, Cohen JB, Chiocca EA, Glorioso JC
  Title
Design and application of oncolytic HSV vectors for glioblastoma therapy.
  Journal
Expert Rev Neurother 9:505-17 (2009)
DOI:10.1586/ern.09.9
Reference
PMID:23115300
  Authors
Lussignol M, Queval C, Bernet-Camard MF, Cotte-Laffitte J, Beau I, Codogno P, Esclatine A
  Title
The herpes simplex virus 1 Us11 protein inhibits autophagy through its interaction with the protein kinase PKR.
  Journal
J Virol 87:859-71 (2013)
DOI:10.1128/JVI.01158-12
Reference
PMID:17229694
  Authors
Sanchez R, Mohr I
  Title
Inhibition of cellular 2'-5' oligoadenylate synthetase by the herpes simplex virus type 1 Us11 protein.
  Journal
J Virol 81:3455-64 (2007)
DOI:10.1128/JVI.02520-06
Reference
PMID:12826401
  Authors
Wysocka J, Herr W
  Title
The herpes simplex virus VP16-induced complex: the makings of a regulatory switch.
  Journal
Trends Biochem Sci 28:294-304 (2003)
DOI:10.1016/S0968-0004(03)00088-4
Reference
PMID:27367734
  Authors
Fleming SB
  Title
Viral Inhibition of the IFN-Induced JAK/STAT Signalling Pathway: Development of Live Attenuated Vaccines by Mutation of Viral-Encoded IFN-Antagonists.
  Journal
Vaccines (Basel) 4:E23 (2016)
DOI:10.3390/vaccines4030023
Reference
PMID:15163721
  Authors
Yokota S, Yokosawa N, Okabayashi T, Suzutani T, Miura S, Jimbow K, Fujii N
  Title
Induction of suppressor of cytokine signaling-3 by herpes simplex virus type 1 contributes to inhibition of the interferon signaling pathway.
  Journal
J Virol 78:6282-6 (2004)
DOI:10.1128/JVI.78.12.6282-6286.2004
Reference
PMID:23864622
  Authors
Gu H, Zheng Y, Roizman B
  Title
Interaction of herpes simplex virus ICP0 with ND10 bodies: a sequential process of adhesion, fusion, and retention.
  Journal
J Virol 87:10244-54 (2013)
DOI:10.1128/JVI.01487-13
Reference
PMID:21994592
  Authors
Tavalai N, Stamminger T
  Title
Interplay between Herpesvirus Infection and Host Defense by PML Nuclear Bodies.
  Journal
Viruses 1:1240-64 (2009)
DOI:10.3390/v1031240
Reference
PMID:21146386
  Authors
Horst D, Verweij MC, Davison AJ, Ressing ME, Wiertz EJ
  Title
Viral evasion of T cell immunity: ancient mechanisms offering new applications.
  Journal
Curr Opin Immunol 23:96-103 (2011)
DOI:10.1016/j.coi.2010.11.005
Reference
PMID:12960333
  Authors
Neumann J, Eis-Hubinger AM, Koch N
  Title
Herpes simplex virus type 1 targets the MHC class II processing pathway for immune evasion.
  Journal
J Immunol 171:3075-83 (2003)
DOI:10.4049/jimmunol.171.6.3075
Reference
PMID:25798530
  Authors
Liu X, Cohen JI
  Title
The role of PI3K/Akt in human herpesvirus infection: From the bench to the bedside.
  Journal
Virology 479-480:568-77 (2015)
DOI:10.1016/j.virol.2015.02.040
Reference
PMID:28468873
  Authors
Vink EI, Smiley JR, Mohr I
  Title
Subversion of Host Responses to Energy Insufficiency by Us3 Supports Herpes Simplex Virus 1 Replication during Stress.
  Journal
J Virol 91:e00295-17 (2017)
DOI:10.1128/JVI.00295-17
Reference
PMID:18508584
  Authors
Sandri-Goldin RM
  Title
The many roles of the regulatory protein ICP27 during herpes simplex virus infection.
  Journal
Front Biosci 13:5241-56 (2008)
DOI:10.2741/3078
Reference
PMID:15078920
  Authors
Sandri-Goldin RM
  Title
Viral regulation of mRNA export.
  Journal
J Virol 78:4389-96 (2004)
DOI:10.1128/JVI.78.9.4389-4396.2004
Reference
PMID:27154074
  Authors
Yu X, He S
  Title
The interplay between human herpes simplex virus infection and the apoptosis and necroptosis cell death pathways.
  Journal
Virol J 13:77 (2016)
DOI:10.1186/s12985-016-0528-0
Related
pathway
pon03040  Spliceosome
pon03050  Proteasome
pon04115  p53 signaling pathway
pon04151  PI3K-Akt signaling pathway
pon04210  Apoptosis
pon04610  Complement and coagulation cascades
pon04612  Antigen processing and presentation
pon04620  Toll-like receptor signaling pathway
pon04622  RIG-I-like receptor signaling pathway
pon04630  JAK-STAT signaling pathway
KO pathway
ko05168   
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