KEGG   PATHWAY: cpla04820
Entry
cpla04820                   Pathway                                
Name
Cytoskeleton in muscle cells - Chiloscyllium plagiosum (whitespotted bambooshark)
Class
Cellular Processes; Cell motility
Pathway map
cpla04820  Cytoskeleton in muscle cells
cpla04820

Organism
Chiloscyllium plagiosum (whitespotted bambooshark) [GN:cpla]
Gene
122539441  [KO:K12753]
122539546  palld; palladin [KO:K22028]
122539695  [KO:K19879]
122539713  [KO:K10056]
122539880  lama2; laminin subunit alpha-2 [KO:K05637]
122539928  [KO:K06236]
122539929  [KO:K12565]
122539933  [KO:K06482]
122539982  [KO:K06584]
122540005  fmnl1a; formin-like protein 1 isoform X1 [KO:K23957]
122540019  [KO:K06493]
122540034  myl4; myosin light chain 4 [KO:K12750]
122540184  hspg2; basement membrane-specific heparan sulfate proteoglycan core protein [KO:K06255]
122540289  capzb; F-actin-capping protein subunit beta isoform X1 [KO:K10365]
122540408  agrn; agrin isoform X1 [KO:K06254]
122540421  eno1a; enolase 1a, (alpha) isoform X1 [KO:K01689] [EC:4.2.1.11]
122540706  [KO:K06257]
122540838  [KO:K06587]
122540982  tmod2; tropomodulin-2 isoform X1 [KO:K10370]
122541073  [KO:K12641]
122541220  [KO:K19721]
122541727  vcla; vinculin a [KO:K05700]
122541754  pdlim1; PDZ and LIM domain protein 1 isoform X1 [KO:K23353]
122541818  [KO:K28413]
122541932  myom2b; myomesin-2 isoform X1 [KO:K24495]
122541946  [KO:K26050]
122542042  [KO:K05865]
122542177  tnnt1; troponin T, slow skeletal muscle isoform X1 [KO:K10372]
122542197  mybpc2a; myosin binding protein Ca isoform X1 [KO:K12558]
122542322  [KO:K10352]
122542343  sun2; SUN domain-containing protein 2 isoform X1 [KO:K19347]
122542349  nid1a; nidogen-1 [KO:K06826]
122542423  [KO:K06825]
122542439  tln2b; talin-2 [KO:K06271]
122542622  tpm1; tropomyosin alpha-1 chain isoform X1 [KO:K10373]
122542711  [KO:K06115]
122542796  [KO:K27382]
122543001  pdlim2; PDZ and LIM domain protein 2 isoform X1 [KO:K23353]
122543100  myl7; myosin regulatory light chain 2, atrial isoform [KO:K12754]
122543237  col9a1b; collagen, type IX, alpha 1b [KO:K08131]
122543254  [KO:K06583]
122543283  [KO:K23957]
122543410  [KO:K01689] [EC:4.2.1.11]
122543429  trim54; tripartite motif-containing protein 54 [KO:K10653]
122543854  [KO:K23932]
122544282  atp1b2b; sodium/potassium-transporting ATPase subunit beta-2b isoform X1 [KO:K01540]
122544463  [KO:K12314]
122544695  [KO:K10373]
122544732  [KO:K06586]
122544773  thbs3a; thrombospondin-3a [KO:K04659]
122546340  [KO:K19879]
122546673  [KO:K14380]
122546928  [KO:K05692]
122547043  [KO:K07610]
122547095  [KO:K17307]
122547285  [KO:K05692]
122547989  [KO:K01539] [EC:7.2.2.13]
122548186  [KO:K12042]
122548505  daam2; disheveled-associated activator of morphogenesis 2 isoform X1 [KO:K04512]
122548517  [KO:K10373]
122548542  tln1; talin-1 isoform X1 [KO:K06271]
122548562  lbr; delta(14)-sterol reductase LBR [KO:K19532] [EC:1.3.1.70]
122548762  [KO:K07597]
122548763  [KO:K07597]
122548768  lama1; laminin subunit alpha-1 [KO:K05637]
122548799  [KO:K05692]
122548800  [KO:K05692]
122548801  [KO:K05692]
122548802  [KO:K05692]
122548823  [KO:K07601]
122548903  [KO:K08131]
122548929  [KO:K27381]
122548948  [KO:K05692]
122548949  [KO:K05692]
122548960  [KO:K12749]
122548969  sdc2; syndecan-2 [KO:K16336]
122549040  myom1b; M-protein, striated muscle isoform X1 [KO:K24495]
122549080  itga1; integrin alpha-1 [KO:K06480]
122549086  [KO:K06481]
122549187  [KO:K10381]
122549232  sntb1; beta-1-syntrophin [KO:K24064]
122549290  itga9; integrin alpha-9 isoform X1 [KO:K06585]
122549439  [KO:K10654]
122549474  dtna; dystrobrevin alpha [KO:K26998]
122549775  itgb8; integrin beta-8 isoform X1 [KO:K06591]
122549831  sgce; epsilon-sarcoglycan isoform X1 [KO:K27061]
122549833  col1a2; collagen alpha-2(I) chain isoform X1 [KO:K06236]
122549979  [KO:K27062]
122549985  itga8; integrin alpha-8 isoform X1 [KO:K06584]
122550009  [KO:K07606]
122550010  [KO:K07606]
122550024  [KO:K25865]
122550082  [KO:K05719]
122550083  [KO:K05719]
122550181  [KO:K24220]
122550328  [KO:K17531] [EC:2.7.11.1]
122550395  sgcb; beta-sarcoglycan isoform X1 [KO:K12566]
122550431  [KO:K05745]
122550471  [KO:K06237]
122550473  [KO:K06237]
122550668  fhl2a; four and a half LIM domains protein 2a isoform X1 [KO:K14380]
122550746  sgcg; gamma-sarcoglycan [KO:K12564]
122551023  [KO:K12755]
122551236  [KO:K19721]
122551335  [KO:K06238]
122551336  [KO:K06238]
122551433  col6a1; collagen alpha-1(VI) chain [KO:K06238]
122551434  col6a2; collagen alpha-2(VI) chain isoform X1 [KO:K06238]
122551435  [KO:K05717]
122551468  [KO:K05738]
122551482  itgav; integrin alpha-V [KO:K06487]
122551499  itga4; integrin alpha-4 isoform X1 [KO:K06483]
122551565  [KO:K06485]
122551601  [KO:K23957]
122551627  itgb6; integrin beta-6 isoform X1 [KO:K06589]
122551664  itgb5; integrin beta-5 isoform X1 [KO:K06588]
122551753  neb; nebulin isoform X1 [KO:K18267]
122551819  [KO:K07610]
122551920  ttn.1; titin [KO:K12567] [EC:2.7.11.1]
122551931  xirp2b; xin actin-binding repeat-containing protein 2 [KO:K27381]
122552376  [KO:K19721]
122552616  [KO:K04659]
122552694  [KO:K21073]
122552802  [KO:K27382]
122552871  sptbn1; spectrin beta chain, non-erythrocytic 1 isoform X1 [KO:K06115]
122553132  [KO:K24066]
122553141  [KO:K26050]
122553271  syne1b; nesprin-1 [KO:K19326]
122553439  ank2b; ankyrin-2b isoform X1 [KO:K09255]
122553563  [KO:K23958]
122553598  nid2a; uncharacterized protein nid2a isoform X1 [KO:K06826]
122553652  daam1a; disheveled-associated activator of morphogenesis 1 isoform X1 [KO:K04512]
122553720  thbs1b; thrombospondin-1 [KO:K16857]
122553748  [KO:K12314]
122553855  capn3a; calpain-3 isoform X1 [KO:K08573] [EC:3.4.22.54]
122554023  [KO:K06115]
122554101  [KO:K19721]
122554684  col11a1a; collagen, type XI, alpha 1a [KO:K19721]
122554866  [KO:K21761]
122555071  dmd; dystrophin isoform X1 [KO:K10366]
122555500  [KO:K01540]
122555674  [KO:K06237]
122556223  atp1b3a; sodium/potassium-transporting ATPase subunit beta-3a [KO:K01540]
122556243  [KO:K06237]
122556419  [KO:K05745]
122556446  [KO:K26050]
122556536  sgcd; delta-sarcoglycan isoform X1 [KO:K12563]
122556562  [KO:K23353]
122556630  myot; myotilin isoform X1 [KO:K19875]
122556683  pdlim7; PDZ and LIM domain protein 7 isoform X1 [KO:K19867]
122556743  [KO:K07606]
122556849  [KO:K19720]
122557143  diaph2; protein diaphanous homolog 2 isoform X1 [KO:K05741]
122557381  col4a6; collagen alpha-6(IV) chain isoform X1 [KO:K06237]
122557382  col4a5; collagen alpha-5(IV) chain isoform X1 [KO:K06237]
122557397  [KO:K01540]
122557620  csrp3; cysteine and glycine-rich protein 3 [KO:K09377]
122557853  [KO:K12043]
122557855  tnnt3a; troponin T type 3a (skeletal, fast) isoform X1 [KO:K12046]
122557860  pdlim3b; PDZ and LIM domain protein 3b isoform X1 [KO:K23353]
122558014  [KO:K12568]
122558085  [KO:K01490] [EC:3.5.4.6]
122558088  [KO:K23342]
122558171  sntb2; beta-2-syntrophin isoform X1 [KO:K24064]
122558293  [KO:K04659]
122558785  [KO:K27488]
122558978  fbln2; fibulin-2 isoform X1 [KO:K17307]
122559078  lmod3; leiomodin-3 isoform X1 [KO:K22030]
122559152  dag1; dystroglycan [KO:K06265]
122559198  [KO:K05865]
122559263  [KO:K10364]
122559337  mybpc1; myosin-binding protein C, slow-type isoform X1 [KO:K12557]
122559533  [KO:K22030]
122559575  fbln1; fibulin-1 isoform X1 [KO:K17307]
122559686  [KO:K10364]
122559782  [KO:K12642]
122559819  dcn; decorin [KO:K04660]
122559946  [KO:K12042]
122560009  [KO:K12042]
122560196  [KO:K12755]
122560295  sdc4; syndecan-4 [KO:K16338]
122560314  col9a3; collagen alpha-3(IX) chain [KO:K08131]
122560325  snta1; alpha-1-syntrophin [KO:K24063]
122560342  [KO:K24220]
122560464  [KO:K10352]
122560574  [KO:K19347]
122560839  lmnb1; lamin-B1 isoform X1 [KO:K07611]
122560984  [KO:K21434]
122561011  mypn; myopalladin isoform X1 [KO:K22028]
122561032  ank3b; ankyrin-3 isoform X1 [KO:K09259]
122561073  ankrd1b; ankyrin repeat domain-containing protein 1b [KO:K21433]
122561199  [KO:K24421]
122561565  sspn; sarcospan [KO:K22194]
122561624  [KO:K12045]
122561631  [KO:K10371]
122561632  [KO:K10371]
122561772  flncb; filamin-C isoform X1 [KO:K27393]
122561940  [KO:K14365]
122562022  [KO:K24220]
122562026  [KO:K24220]
122562058  [KO:K10352]
122562165  [KO:K05692]
122562333  itgb4; integrin beta-4 [KO:K06525]
122562340  [KO:K24220]
122562341  [KO:K24220]
122562654  [KO:K10351]
122562942  [KO:K12045]
122562943  [KO:K09377]
122562952  [KO:K24494]
122563038  capza1b; F-actin-capping protein subunit alpha-1b [KO:K10364]
122563090  [KO:K01490] [EC:3.5.4.6]
122563123  [KO:K04660]
122563210  [KO:K22030]
122563234  tnni1b; troponin I type 1b (skeletal, slow) isoform X1 [KO:K10371]
122563297  ampd1; AMP deaminase 1 isoform X1 [KO:K01490] [EC:3.5.4.6]
122563395  [KO:K08131]
122563469  myom3; myomesin-3 isoform X1 [KO:K24495]
122563500  [KO:K16337]
122563598  [KO:K10655] [EC:2.3.2.27]
122563709  fhl3a; four and a half LIM domains protein 3 [KO:K24414]
122563842  [KO:K10351]
122564394  tmod1; tropomodulin-1 isoform X1 [KO:K10370]
122564606  [KO:K19721]
122564621  col27a1b; collagen alpha-1(XXVII) chain B [KO:K19721]
122564987  sptan1; spectrin alpha chain, non-erythrocytic 1 isoform X1 [KO:K06114]
122565066  [KO:K04659]
122565150  [KO:K09290]
122565261  lmnb2; lamin-B2 [KO:K07611]
122565550  fbn2b; fibrillin-2b [KO:K23342]
Reference
  Authors
Clark KA, McElhinny AS, Beckerle MC, Gregorio CC
  Title
Striated muscle cytoarchitecture: an intricate web of form and function.
  Journal
Annu Rev Cell Dev Biol 18:637-706 (2002)
DOI:10.1146/annurev.cellbio.18.012502.105840
Reference
  Authors
Mukund K, Subramaniam S
  Title
Skeletal muscle: A review of molecular structure and function, in health and disease.
  Journal
Wiley Interdiscip Rev Syst Biol Med 12:e1462 (2020)
DOI:10.1002/wsbm.1462
Reference
  Authors
Stroud MJ, Banerjee I, Veevers J, Chen J
  Title
Linker of nucleoskeleton and cytoskeleton complex proteins in cardiac structure, function, and disease.
  Journal
Circ Res 114:538-48 (2014)
DOI:10.1161/CIRCRESAHA.114.301236
Reference
  Authors
Henderson CA, Gomez CG, Novak SM, Mi-Mi L, Gregorio CC
  Title
Overview of the Muscle Cytoskeleton.
  Journal
Compr Physiol 7:891-944 (2017)
DOI:10.1002/cphy.c160033
Reference
  Authors
Csapo R, Gumpenberger M, Wessner B
  Title
Skeletal Muscle Extracellular Matrix - What Do We Know About Its Composition, Regulation, and Physiological Roles? A Narrative Review.
  Journal
Front Physiol 11:253 (2020)
DOI:10.3389/fphys.2020.00253
Reference
  Authors
Pinch M, Guth R, Samanta MP, Chaidez A, Unguez GA
  Title
The myogenic electric organ of Sternopygus macrurus: a non-contractile tissue with a skeletal muscle transcriptome.
  Journal
PeerJ 4:e1828 (2016)
DOI:10.7717/peerj.1828
Reference
  Authors
Sequeira V, Nijenkamp LL, Regan JA, van der Velden J
  Title
The physiological role of cardiac cytoskeleton and its alterations in heart failure.
  Journal
Biochim Biophys Acta 1838:700-22 (2014)
DOI:10.1016/j.bbamem.2013.07.011
Reference
  Authors
Zhang B, Powers JD, McCulloch AD, Chi NC
  Title
Nuclear mechanosignaling in striated muscle diseases.
  Journal
Front Physiol 14:1126111 (2023)
DOI:10.3389/fphys.2023.1126111
Reference
  Authors
Al-Amoudi A, Castano-Diez D, Devos DP, Russell RB, Johnson GT, Frangakis AS
  Title
The three-dimensional molecular structure of the desmosomal plaque.
  Journal
Proc Natl Acad Sci U S A 108:6480-5 (2011)
DOI:10.1073/pnas.1019469108
Reference
  Authors
Sikora M, Ermel UH, Seybold A, Kunz M, Calloni G, Reitz J, Vabulas RM, Hummer G, Frangakis AS
  Title
Desmosome architecture derived from molecular dynamics simulations and cryo-electron tomography.
  Journal
Proc Natl Acad Sci U S A 117:27132-27140 (2020)
DOI:10.1073/pnas.2004563117
Reference
  Authors
Xu XP, Kim E, Swift M, Smith JW, Volkmann N, Hanein D
  Title
Three-Dimensional Structures of Full-Length, Membrane-Embedded Human alpha(IIb)beta(3) Integrin Complexes.
  Journal
Biophys J 110:798-809 (2016)
DOI:10.1016/j.bpj.2016.01.016
Reference
  Authors
Wang W, Shi Z, Jiao S, Chen C, Wang H, Liu G, Wang Q, Zhao Y, Greene MI, Zhou Z
  Title
Structural insights into SUN-KASH complexes across the nuclear envelope.
  Journal
Cell Res 22:1440-52 (2012)
DOI:10.1038/cr.2012.126
Reference
  Authors
Sosa BA, Kutay U, Schwartz TU
  Title
Structural insights into LINC complexes.
  Journal
Curr Opin Struct Biol 23:285-91 (2013)
DOI:10.1016/j.sbi.2013.03.005
Reference
  Authors
Cruz VE, Esra Demircioglu F, Schwartz TU
  Title
Structural Analysis of Different LINC Complexes Reveals Distinct Binding Modes.
  Journal
J Mol Biol 432:6028-6041 (2020)
DOI:10.1016/j.jmb.2020.09.019
Reference
  Authors
Schuler SC, Liu Y, Dumontier S, Grandbois M, Le Moal E, Cornelison D, Bentzinger CF
  Title
Extracellular matrix: Brick and mortar in the skeletal muscle stem cell niche.
  Journal
Front Cell Dev Biol 10:1056523 (2022)
DOI:10.3389/fcell.2022.1056523
Reference
  Authors
Brull A, Morales Rodriguez B, Bonne G, Muchir A, Bertrand AT
  Title
The Pathogenesis and Therapies of Striated Muscle Laminopathies.
  Journal
Front Physiol 9:1533 (2018)
DOI:10.3389/fphys.2018.01533
Reference
  Authors
Storey EC, Fuller HR
  Title
Genotype-Phenotype Correlations in Human Diseases Caused by Mutations of LINC Complex-Associated Genes: A Systematic Review and Meta-Summary.
  Journal
Cells 11:cells11244065 (2022)
DOI:10.3390/cells11244065
Related
pathway
cpla04512  ECM-receptor interaction
cpla04814  Motor proteins
KO pathway
ko04820   

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