KEGG   PATHWAY: csab05132
Entry
csab05132                   Pathway                                
Name
Salmonella infection - Chlorocebus sabaeus (green monkey)
Description
Salmonella infection usually presents as a self-limiting gastroenteritis or the more severe typhoid fever and bacteremia. The common disease-causing Salmonella species in human is a single species, Salmonella enterica, which has numerous serovars.
Following intestinal colonization Salmonella inject effector proteins into the host cells using a type III secretion system (T3SS), T3SS1. Then a small group of effector proteins induce rearrangement of the actin cytoskeleton resulting in membrane ruffles and rapid internalization of the bacteria.The T3SS2 is responsible for translocating effector proteins that direct Salmonella-containing vacuole (SCV) maturation. The majority of the bacteria are known to survive and replicate in SCV.
Class
Human Diseases; Infectious disease: bacterial
Pathway map
csab05132  Salmonella infection
csab05132

Disease
H00111  Typhoid fever
Organism
Chlorocebus sabaeus (green monkey) [GN:csab]
Gene
103214430  KPNA3; karyopherin subunit alpha 3 [KO:K23583]
103215020  [KO:K05692]
103215469  TNFRSF10B; TNF receptor superfamily member 10b [KO:K04722]
103215472  TNFRSF10A; TNF receptor superfamily member 10a [KO:K04722]
103215570  DCTN6; dynactin subunit 6 [KO:K10428]
103215686  IKBKB; inhibitor of nuclear factor kappa B kinase subunit beta [KO:K07209] [EC:2.7.11.10]
103215844  MAPK8; mitogen-activated protein kinase 8 [KO:K04440] [EC:2.7.11.24]
103216382  CHUK; conserved helix-loop-helix ubiquitous kinase [KO:K04467] [EC:2.7.11.10]
103216438  ACTR1A; ARP1 actin-related protein 1 homolog A, centractin alpha [KO:K16575]
103216486  MYL9; myosin light chain 9 [KO:K12755]
103216537  CASP7; caspase 7 [KO:K04397] [EC:3.4.22.60]
103216817  TCF7L2; transcription factor 7 like 2 [KO:K04491]
103216844  TUBA3E; tubulin alpha 3e [KO:K07374]
103216959  ACTR3; ARP3 actin related protein 3 homolog [KO:K18584]
103217064  KIF5C; kinesin family member 5C [KO:K10396] [EC:5.6.1.3]
103217237  [KO:K05692]
103217307  DYNC1I2; dynein cytoplasmic 1 intermediate chain 2 [KO:K10415]
103217468  NCKAP1; NCK associated protein 1 [KO:K05750]
103217637  CASP8; caspase 8 [KO:K04398] [EC:3.4.22.61]
103217860  ARPC2; actin related protein 2/3 complex subunit 2 [KO:K05758]
103217904  TUBA4A; tubulin alpha 4a [KO:K07374]
103218446  TNFRSF1A; TNF receptor superfamily member 1A [KO:K03158]
103218453  GAPDH; glyceraldehyde-3-phosphate dehydrogenase [KO:K00134] [EC:1.2.1.12]
103218540  M6PR; mannose-6-phosphate receptor, cation dependent [KO:K10089]
103218712  PIK3C2G; phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma [KO:K00923] [EC:2.7.1.154]
103218912  [KO:K05756]
103218937  TLR4; toll like receptor 4 [KO:K10160]
103219027  TXN; thioredoxin [KO:K03671]
103219258  DCTN3; dynactin subunit 3 [KO:K10425]
103219323  [KO:K05692]
103219556  [KO:K08738]
103219950  TCF7L1; transcription factor 7 like 1 [KO:K04490]
103220033  DCTN1; dynactin subunit 1 [KO:K04648]
103220149  ACTR2; ARP2 actin related protein 2 homolog [KO:K17260]
103220383  DYNC2LI1; dynein cytoplasmic 2 light intermediate chain 1 [KO:K10417]
103220528  NLRC4; NLR family CARD domain containing 4 [KO:K12805]
103220717  RHOB; ras homolog family member B [KO:K07856]
103220805  ROCK2; Rho associated coiled-coil containing protein kinase 2 [KO:K17388] [EC:2.7.11.39]
103221064  MYD88; myeloid differentiation primary response 88 [KO:K04729]
103221212  PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha [KO:K00922] [EC:2.7.1.153]
103221232  [KO:K03671]
103221246  TNFSF10; tumor necrosis factor superfamily member 10 [KO:K04721]
103221397  SNX18; sorting nexin 18 [KO:K17923]
103221436  HSP90AB1; heat shock protein 90 alpha family class B member 1 [KO:K04079]
103221478  KLC4; kinesin light chain 4 [KO:K10407]
103221595  MAPK13; mitogen-activated protein kinase 13 [KO:K04441] [EC:2.7.11.24]
103221596  MAPK14; mitogen-activated protein kinase 14 [KO:K04441] [EC:2.7.11.24]
103221651  BAK1; BCL2 antagonist/killer 1 [KO:K14021]
103221819  TUBB; tubulin beta class I [KO:K07375]
103221840  [KO:K05759]
103222274  [KO:K07375]
103222280  [KO:K07375]
103222283  RIPK1; receptor interacting serine/threonine kinase 1 [KO:K02861] [EC:2.7.11.1]
103222314  EXOC2; exocyst complex component 2 [KO:K17637]
103222505  PIK3C3; phosphatidylinositol 3-kinase catalytic subunit type 3 [KO:K00914] [EC:2.7.1.137]
103222701  MYL12B; myosin light chain 12B [KO:K12757]
103222703  MYL12A; myosin light chain 12A [KO:K12757]
103222808  TUBB6; tubulin beta 6 class V [KO:K07375]
103222884  TUBA8; tubulin alpha 8 [KO:K07374]
103222941  MAPK1; mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
103223247  TXN2; thioredoxin 2 [KO:K03671]
103223274  CYTH4; cytohesin 4 [KO:K18441]
103223342  TAB1; TGF-beta activated kinase 1 (MAP3K7) binding protein 1 [KO:K04403]
103223551  MAPK11; mitogen-activated protein kinase 11 [KO:K04441] [EC:2.7.11.24]
103223553  MAPK12; mitogen-activated protein kinase 12 [KO:K04441] [EC:2.7.11.24]
103224015  S100A10; S100 calcium binding protein A10 [KO:K17274]
103224193  KLC2; kinesin light chain 2 [KO:K10407]
103224726  JUN; Jun proto-oncogene, AP-1 transcription factor subunit [KO:K04448]
103224843  [KO:K08738]
103225132  NAIP; NLR family apoptosis inhibitory protein [KO:K12807]
103225423  CDC42; cell division cycle 42 [KO:K04393]
103225546  PLEKHM2; pleckstrin homology and RUN domain containing M2 [KO:K15348]
103225637  PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta [KO:K00922] [EC:2.7.1.153]
103225665  [KO:K08738]
103226143  MYL7; myosin light chain 7 [KO:K12754]
103226186  RALA; RAS like proto-oncogene A [KO:K07834]
103226195  VPS41; VPS41, HOPS complex subunit [KO:K20184]
103226216  ELMO1; engulfment and cell motility 1 [KO:K12366]
103226280  NOD1; nucleotide binding oligomerization domain containing 1 [KO:K08727]
103226390  IL6; interleukin 6 [KO:K05405]
103226521  DYNC1I1; dynein cytoplasmic 1 intermediate chain 1 [KO:K10415]
103226710  PIK3CG; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma [KO:K21289] [EC:2.7.1.153]
103226817  WASL; Wiskott-Aldrich syndrome like [KO:K23612]
103226913  PODXL; podocalyxin like [KO:K06817]
103226921  EXOC4; exocyst complex component 4 [KO:K06111]
103227169  [KO:K10418]
103227272  ACTR3B; ARP3 actin related protein 3 homolog B [KO:K18584]
103227364  RELA; RELA proto-oncogene, NF-kB subunit [KO:K04735]
103227444  CTNNB1; catenin beta 1 [KO:K02105]
103227528  FYCO1; FYVE and coiled-coil domain containing 1 [KO:K21954]
103227629  RHOA; ras homolog family member A [KO:K04513]
103227720  [KO:K10161]
103227948  ARL8B; ADP ribosylation factor like GTPase 8B [KO:K07955]
103227981  ARPC4; actin related protein 2/3 complex subunit 4 [KO:K05755]
103227998  BRK1; BRICK1, SCAR/WAVE actin nucleating complex subunit [KO:K05752]
103228018  [KO:K08738]
103228031  RAF1; Raf-1 proto-oncogene, serine/threonine kinase [KO:K04366] [EC:2.7.11.1]
103228088  RAB7A; RAB7A, member RAS oncogene family [KO:K07897]
103228184  KPNA1; karyopherin subunit alpha 1 [KO:K23940]
103228724  RIPK3; receptor interacting serine/threonine kinase 3 [KO:K08847] [EC:2.7.11.1]
103228823  NFKBIA; NFKB inhibitor alpha [KO:K04734]
103228947  ARF6; ADP ribosylation factor 6 [KO:K07941]
103229067  EXOC5; exocyst complex component 5 [KO:K19984]
103229088  ACTR10; actin-related protein 10 homolog [KO:K16576]
103229147  RHOJ; ras homolog family member J [KO:K07864]
103229352  FOS; Fos proto-oncogene, AP-1 transcription factor subunit [KO:K04379]
103229725  DYNC1H1; dynein cytoplasmic 1 heavy chain 1 [KO:K10413]
103229726  HSP90AA1; heat shock protein 90 alpha family class A member 1 [KO:K04079]
103229784  AKT1; AKT serine/threonine kinase 1 [KO:K04456] [EC:2.7.11.1]
103229790  AHNAK2; AHNAK nucleoprotein 2 [KO:K23934]
103229803  [KO:K10427]
103229927  [KO:K10407]
103229966  ARF1; ADP ribosylation factor 1 [KO:K07937]
103229996  ACBD3; acyl-CoA binding domain containing 3 [KO:K23935]
103230033  TLR5; toll like receptor 5 [KO:K10168]
103230208  RAB7B; RAB7B, member RAS oncogene family [KO:K07898]
103230248  PIK3C2B; phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta [KO:K00923] [EC:2.7.1.154]
103230312  ARL8A; ADP ribosylation factor like GTPase 8A [KO:K07955]
103230364  PTPRC; protein tyrosine phosphatase, receptor type C [KO:K06478] [EC:3.1.3.48]
103230451  ARPC5; actin related protein 2/3 complex subunit 5 [KO:K05754]
103230532  MAPK3; mitogen-activated protein kinase 3 [KO:K04371] [EC:2.7.11.24]
103230823  [KO:K05692]
103230869  AKT3; AKT serine/threonine kinase 3 [KO:K04456] [EC:2.7.11.1]
103230879  MYLPF; myosin light chain, phosphorylatable, fast skeletal muscle [KO:K12758]
103230928  NLRP3; NLR family pyrin domain containing 3 [KO:K12800]
103231357  [KO:K12799]
103231620  RAB9A; RAB9A, member RAS oncogene family [KO:K07899]
103231769  TAB3; TGF-beta activated kinase 1/MAP3K7 binding protein 3 [KO:K12793]
103232420  RAB9B; RAB9B, member RAS oncogene family [KO:K07900]
103232488  PAK3; p21 (RAC1) activated kinase 3 [KO:K05733] [EC:2.7.11.1]
103232815  IRAK1; interleukin 1 receptor associated kinase 1 [KO:K04730] [EC:2.7.11.1]
103232822  FLNA; filamin A [KO:K04437]
103232832  IKBKG; inhibitor of nuclear factor kappa B kinase subunit gamma [KO:K07210]
103233128  DYNC1LI2; dynein cytoplasmic 1 light intermediate chain 2 [KO:K10416]
103233145  MLKL; mixed lineage kinase domain like pseudokinase [KO:K08849] [EC:2.7.11.1]
103233281  FHOD1; formin homology 2 domain containing 1 [KO:K23938]
103233291  TRADD; TNFRSF1A associated via death domain [KO:K03171]
103233354  DYNLRB2; dynein light chain roadblock-type 2 [KO:K10419]
103233496  [KO:K07375]
103233717  MAP2K2; mitogen-activated protein kinase kinase 2 [KO:K04369] [EC:2.7.12.2]
103233776  [KO:K07375]
103233777  [KO:K07375]
103233823  MAP2K7; mitogen-activated protein kinase kinase 7 [KO:K04431] [EC:2.7.12.2]
103233911  DNM2; dynamin 2 [KO:K23484]
103234014  STX10; syntaxin 10 [KO:K23937]
103234039  PKN1; protein kinase N1 [KO:K06071] [EC:2.7.11.13]
103234702  AKT2; AKT serine/threonine kinase 2 [KO:K04456] [EC:2.7.11.1]
103234862  KLC3; kinesin light chain 3 [KO:K10407]
103234977  CYTH2; cytohesin 2 [KO:K18441]
103235004  BAX; BCL2 associated X, apoptosis regulator [KO:K02159]
103235048  RRAS; related RAS viral (r-ras) oncogene homolog [KO:K07829]
103235786  CXCL8; C-X-C motif chemokine ligand 8 [KO:K10030]
103235918  MAPK10; mitogen-activated protein kinase 10 [KO:K04440] [EC:2.7.11.24]
103236047  NFKB1; nuclear factor kappa B subunit 1 [KO:K02580]
103236088  LEF1; lymphoid enhancer binding factor 1 [KO:K04492]
103236415  [KO:K10159]
103236614  CASP3; caspase 3 [KO:K02187] [EC:3.4.22.56]
103236665  [KO:K04079]
103236981  LY96; lymphocyte antigen 96 [KO:K05400]
103237096  RIPK2; receptor interacting serine/threonine kinase 2 [KO:K08846] [EC:2.7.11.1]
103237427  [KO:K10426]
103237430  MYC; v-myc avian myelocytomatosis viral oncogene homolog [KO:K04377]
103237554  TRAF6; TNF receptor associated factor 6 [KO:K03175] [EC:2.3.2.27]
103237567  GSDMD; gasdermin D [KO:K20917]
103237818  TUBAL3; tubulin alpha like 3 [KO:K07374]
103238031  ABI1; abl interactor 1 [KO:K23649]
103238089  KIF5B; kinesin family member 5B [KO:K10396] [EC:5.6.1.3]
103238180  IRAK4; interleukin 1 receptor associated kinase 4 [KO:K04733] [EC:2.7.11.1]
103238260  TUBA1B; tubulin alpha 1b [KO:K07374]
103238261  TUBA1A; tubulin alpha 1a [KO:K07374]
103238262  [KO:K07374]
103238442  NCKAP1L; NCK associated protein 1 like [KO:K05750]
103238494  RAB5B; RAB5B, member RAS oncogene family [KO:K07888]
103238574  DCTN2; dynactin subunit 2 [KO:K10424]
103238976  HSP90B1; heat shock protein 90 beta family member 1 [KO:K09487]
103239122  MYL2; myosin light chain 2 [KO:K10351]
103239255  DYNLL1; dynein light chain LC8-type 1 [KO:K10418]
103239305  VPS33A; VPS33A, CORVET/HOPS core subunit [KO:K20182]
103239501  KIF5A; kinesin family member 5A [KO:K10396] [EC:5.6.1.3]
103239525  ARPC3; actin related protein 2/3 complex subunit 3 [KO:K05756]
103239540  [KO:K07375]
103239564  TUBB4B; tubulin beta 4B class IVb [KO:K07375]
103239600  TRAF2; TNF receptor associated factor 2 [KO:K03173] [EC:2.3.2.27]
103239827  [KO:K08738]
103239883  ARPC5L; actin related protein 2/3 complex subunit 5 like [KO:K05754]
103239945  MYO6; myosin VI [KO:K10358]
103240115  MAP3K7; mitogen-activated protein kinase kinase kinase 7 [KO:K04427] [EC:2.7.11.25]
103240159  TAB2; TGF-beta activated kinase 1/MAP3K7 binding protein 2 [KO:K04404]
103240792  SNX9; sorting nexin 9 [KO:K17923]
103240805  DYNLT1; dynein light chain Tctex-type 1 [KO:K10420]
103240948  [KO:K05692]
103240990  [KO:K08738]
103241091  ACTR1B; ARP1 actin-related protein 1 homolog B, centractin beta [KO:K16575]
103241213  GCC2; GRIP and coiled-coil domain containing 2 [KO:K20282]
103241278  IL1B; interleukin 1 beta [KO:K04519]
103241393  KPNA4; karyopherin subunit alpha 4 [KO:K23583]
103241448  ARHGEF26; Rho guanine nucleotide exchange factor 26 [KO:K13744]
103241599  PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta [KO:K00922] [EC:2.7.1.153]
103241745  RAB5A; RAB5A, member RAS oncogene family [KO:K07887]
103241939  AHNAK; AHNAK nucleoprotein [KO:K23934]
103242059  DYNC1LI1; dynein cytoplasmic 1 light intermediate chain 1 [KO:K10416]
103242107  RILP; Rab interacting lysosomal protein [KO:K13883]
103242212  PIK3C2A; phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha [KO:K00923] [EC:2.7.1.154]
103242213  PFN1; profilin 1 [KO:K05759]
103242403  MAP2K4; mitogen-activated protein kinase kinase 4 [KO:K04430] [EC:2.7.12.2]
103242535  MAP2K3; mitogen-activated protein kinase kinase 3 [KO:K04432] [EC:2.7.12.2]
103242859  DYNLL2; dynein light chain LC8-type 2 [KO:K10418]
103243012  EXOC7; exocyst complex component 7 [KO:K07195]
103243132  MAP2K6; mitogen-activated protein kinase kinase 6 [KO:K04433] [EC:2.7.12.2]
103243258  ARL17A; ADP ribosylation factor like GTPase 17A [KO:K07937]
103243285  PLEKHM1; pleckstrin homology and RUN domain containing M1 [KO:K23282]
103243420  RAB5C; RAB5C, member RAS oncogene family [KO:K07889]
103243432  TUBB1; tubulin beta 1 class VI [KO:K07375]
103243663  CYTH1; cytohesin 1 [KO:K18441]
103243719  ACTG1; actin gamma 1 [KO:K05692]
103244166  BCL2; BCL2, apoptosis regulator [KO:K02161]
103244190  [KO:K08738]
103244543  TCF7; transcription factor 7 (T-cell specific, HMG-box) [KO:K02620]
103244544  SKP1; S-phase kinase associated protein 1 [KO:K03094]
103244616  CSE1L; chromosome segregation 1 like [KO:K18423]
103244663  CD14; CD14 molecule [KO:K04391]
103244802  DCTN4; dynactin subunit 4 [KO:K10426]
103244865  CYFIP2; cytoplasmic FMR1 interacting protein 2 [KO:K05749]
103244982  ELMO2; engulfment and cell motility 2 [KO:K18985]
103245051  PFN3; profilin 3 [KO:K05759]
103245120  MAPK9; mitogen-activated protein kinase 9 [KO:K04440] [EC:2.7.11.24]
103245285  FBXO22; F-box protein 22 [KO:K10302]
103245305  SNX33; sorting nexin 33 [KO:K17923]
103245451  MAP2K1; mitogen-activated protein kinase kinase 1 [KO:K04368] [EC:2.7.12.2]
103245532  ANXA2; annexin A2 [KO:K17092]
103245758  FADD; Fas associated via death domain [KO:K02373]
103245809  VPS18; VPS18, CORVET/HOPS core subunit [KO:K20181]
103245986  CYFIP1; cytoplasmic FMR1 interacting protein 1 [KO:K05749]
103246099  VPS39; VPS39, HOPS complex subunit [KO:K20183]
103246189  RHOH; ras homolog family member H [KO:K07873]
103246211  TLR6; toll like receptor 6 [KO:K10169]
103246363  HRAS; HRas proto-oncogene, GTPase [KO:K02833]
103246516  MYL5; myosin light chain 5 [KO:K12753]
103246683  MYL10; myosin light chain 10 [KO:K12756]
103246791  [KO:K05757]
103246809  CYTH3; cytohesin 3 [KO:K18441]
103246815  RAC1; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) [KO:K04392]
103246949  [KO:K05757]
103246953  ACTB; actin beta [KO:K05692]
103247047  VPS16; VPS16, CORVET/HOPS core subunit [KO:K20180]
103247464  DYNLT3; dynein light chain Tctex-type 3 [KO:K10420]
103247857  [KO:K07374]
103247977  RHOG; ras homolog family member G [KO:K07863]
103248057  RPS3; ribosomal protein S3 [KO:K02985]
103248093  PAK1; p21 (RAC1) activated kinase 1 [KO:K04409] [EC:2.7.11.1]
103248332  BIRC3; baculoviral IAP repeat containing 3 [KO:K16060]
103248333  BIRC2; baculoviral IAP repeat containing 2 [KO:K16060]
103248352  DYNC2H1; dynein cytoplasmic 2 heavy chain 1 [KO:K10414]
103248363  [KO:K01370] [EC:3.4.22.36]
103248365  CASP1; caspase 1 [KO:K01370] [EC:3.4.22.36]
103248366  [KO:K04395] [EC:3.4.22.58]
103248367  CASP4; caspase 4 [KO:K04394] [EC:3.4.22.57 3.4.22.64]
103248464  IL18; interleukin 18 [KO:K05482]
103248617  VPS11; VPS11, CORVET/HOPS core subunit [KO:K20179]
103248770  DYNLRB1; dynein light chain roadblock-type 1 [KO:K10419]
103248791  TIRAP; TIR domain containing adaptor protein [KO:K05403]
103248933  [KO:K01370] [EC:3.4.22.36]
103249043  WASF3; WAS protein family member 3 [KO:K06083]
Compound
C00338  Lipopolysaccharide
C01194  1-Phosphatidyl-D-myo-inositol
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
Reference
PMID:28875943
  Authors
Bernal-Bayard J, Ramos-Morales F
  Title
Molecular Mechanisms Used by Salmonella to Evade the Immune System.
  Journal
Curr Issues Mol Biol 25:133-168 (2018)
DOI:10.21775/cimb.025.133
Reference
PMID:28848711
  Authors
Hume PJ, Singh V, Davidson AC, Koronakis V
  Title
Swiss Army Pathogen: The Salmonella Entry Toolkit.
  Journal
Front Cell Infect Microbiol 7:348 (2017)
DOI:10.3389/fcimb.2017.00348
Reference
PMID:31402916
  Authors
Wemyss MA, Pearson JS
  Title
Host Cell Death Responses to Non-typhoidal Salmonella Infection.
  Journal
Front Immunol 10:1758 (2019)
DOI:10.3389/fimmu.2019.01758
Reference
PMID:27974148
  Authors
Bierschenk D, Boucher D, Schroder K
  Title
Salmonella-induced inflammasome activation in humans.
  Journal
Mol Immunol 86:38-43 (2017)
DOI:10.1016/j.molimm.2016.11.009
Reference
PMID:29477730
  Authors
Pinaud L, Sansonetti PJ, Phalipon A
  Title
Host Cell Targeting by Enteropathogenic Bacteria T3SS Effectors.
  Journal
Trends Microbiol 26:266-283 (2018)
DOI:10.1016/j.tim.2018.01.010
Reference
PMID:25749450
  Authors
LaRock DL, Chaudhary A, Miller SI
  Title
Salmonellae interactions with host processes.
  Journal
Nat Rev Microbiol 13:191-205 (2015)
DOI:10.1038/nrmicro3420
Reference
PMID:17983751
  Authors
Ramsden AE, Holden DW, Mota LJ
  Title
Membrane dynamics and spatial distribution of Salmonella-containing vacuoles.
  Journal
Trends Microbiol 15:516-24 (2007)
DOI:10.1016/j.tim.2007.10.002
Reference
PMID:22702524
  Authors
van der Heijden J, Finlay BB
  Title
Type III effector-mediated processes in Salmonella infection.
  Journal
Future Microbiol 7:685-703 (2012)
DOI:10.2217/fmb.12.49
Reference
PMID:27222578
  Authors
Galan JE
  Title
Typhoid toxin provides a window into typhoid fever and the biology of Salmonella Typhi.
  Journal
Proc Natl Acad Sci U S A 113:6338-44 (2016)
DOI:10.1073/pnas.1606335113
Reference
PMID:19157959
  Authors
McGhie EJ, Brawn LC, Hume PJ, Humphreys D, Koronakis V
  Title
Salmonella takes control: effector-driven manipulation of the host.
  Journal
Curr Opin Microbiol 12:117-24 (2009)
DOI:10.1016/j.mib.2008.12.001
Reference
PMID:12675800
  Authors
Miao EA, Brittnacher M, Haraga A, Jeng RL, Welch MD, Miller SI
  Title
Salmonella effectors translocated across the vacuolar membrane interact with the actin cytoskeleton.
  Journal
Mol Microbiol 48:401-15 (2003)
DOI:10.1046/j.1365-2958.2003.t01-1-03456.x
Reference
PMID:17074883
  Authors
Patel JC, Galan JE
  Title
Differential activation and function of Rho GTPases during Salmonella-host cell interactions.
  Journal
J Cell Biol 175:453-63 (2006)
DOI:10.1083/jcb.200605144
Reference
PMID:18411289
  Authors
Wasylnka JA, Bakowski MA, Szeto J, Ohlson MB, Trimble WS, Miller SI, Brumell JH
  Title
Role for myosin II in regulating positioning of Salmonella-containing vacuoles and intracellular replication.
  Journal
Infect Immun 76:2722-35 (2008)
DOI:10.1128/IAI.00152-08
Reference
PMID:10499590
  Authors
Fu Y, Galan JE
  Title
A salmonella protein antagonizes Rac-1 and Cdc42 to mediate host-cell recovery after bacterial invasion.
  Journal
Nature 401:293-7 (1999)
DOI:10.1038/45829
Related
pathway
csab04010  MAPK signaling pathway
csab04064  NF-kappa B signaling pathway
csab04210  Apoptosis
csab04217  Necroptosis
csab04621  NOD-like receptor signaling pathway
KO pathway
ko05132   

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