KEGG ORTHOLOGY: K04979

ORTHOLOGY: K04979

Entry

K04979                      KO

Symbol

TRPM4

Name

transient receptor potential cation channel subfamily M member 4

Pathway

map04911

Insulin secretion

Disease

H00710

Erythrokeratodermia variabilis

H01263

Progressive cardiac conduction defect (PCCD)

Brite

KEGG Orthology (KO) [BR:ko00001]
09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    K04979  TRPM4; transient receptor potential cation channel subfamily M member 4
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K04979  TRPM4; transient receptor potential cation channel subfamily M member 4
Ion channels [BR:ko04040]
Voltage-gated cation channels
  Transient receptor potential channel (TRP)
   K04979  TRPM4; transient receptor potential cation channel subfamily M member 4

Other DBs

GO:	0005262 0005227

TC:

1.A.4.5.4

Genes

HSA:	54795(TRPM4)

PTR:	456197(TRPM4)

PPS:	100968799(TRPM4)

PON:	100460849(TRPM4)

PPYG:

129020253(TRPM4)

NLE:	100583074(TRPM4)

HMH:	116478185(TRPM4)

SSYN:

129461282(TRPM4)

MCC:	114675588 719120(TRPM4)

MCF:	102145147(TRPM4)

MTHB:

126943542

MNI:	105497347(TRPM4)

CSAB:

103235539(TRPM4)

CATY:

105595279(TRPM4)

PANU:

101000720(TRPM4)

TGE:	112613310(TRPM4)

MLEU:

105539156(TRPM4)

RRO:	104667182(TRPM4)

RBB:

108535847

TFN:	117091555(TRPM4)

PTEH:

111519901 111534884 116418573(TRPM4) 116418574

CANG:

105514869

CJC:	100408384(TRPM4)

SBQ:	101053068(TRPM4)

CIMI:

108283920(TRPM4)

ANAN:

105724130(TRPM4)

CSYR:

103266549(TRPM4)

MMUR:

105865680(TRPM4)

LCAT:

123623834(TRPM4)

PCOQ:

105809430(TRPM4)

OGA:	100945539(TRPM4)

MMU:	68667(Trpm4)

MCAL:

110298761(Trpm4)

MPAH:

110320099(Trpm4)

RNO:	171143(Trpm4)

MCOC:

116102190(Trpm4)

ANU:	117720915(Trpm4)

ASYL:

127669359(Trpm4)

MUN:	110560647(Trpm4)

CGE:	100754433(Trpm4)

MAUA:

101823955(Trpm4)

PROB:

127213688(Trpm4)

PLEU:

114684643 114687161

MORG:

121450175(Trpm4)

MFOT:

126488174

AAMP:

119802689(Trpm4)

NGI:	103743652(Trpm4)

HGL:	101707093(Trpm4)

CPOC:

100726173(Trpm4)

CCAN:

109701420(Trpm4)

DORD:

105994348(Trpm4)

DSP:	122125888(Trpm4)

PLOP:

125368251(Trpm4)

NCAR:

124967027

MMMA:

107151258(Trpm4)

ITI:	101955620(Trpm4)

OCU:

127487003

OPI:	101530965(TRPM4)

TUP:	102492362(TRPM4)

GVR:	103587768(TRPM4)

CFA:	484385(TRPM4)

CLUD:

112645161(TRPM4)

VVP:	112931275(TRPM4)

VLG:	121484418(TRPM4)

NPO:	129499928(TRPM4)

AML:	100469579(TRPM4)

UMR:	103657249(TRPM4)

UAH:	113243311(TRPM4)

UAR:	123776294(TRPM4)

ELK:

111160558

LLV:

125088680

MPUF:

101682243(TRPM4)

MNP:	132005647(TRPM4)

MLK:	131818366(TRPM4)

NVS:	122911832(TRPM4)

ORO:	101368019(TRPM4)

EJU:	114199634(TRPM4)

ZCA:	113936088(TRPM4)

MLX:	117998256(TRPM4)

NSU:	110572934(TRPM4)

LWW:	102730110(TRPM4)

FCA:	101083051(TRPM4)

PYU:	121018758(TRPM4)

PBG:	122494834(TRPM4)

PVIV:

125153223(TRPM4)

LRUF:

124510921

LGF:	123578058(TRPM4)

AJU:

106988668

PTG:	102965439(TRPM4)

PPAD:

109253084(TRPM4)

PUC:

125916135

PLEZ:

122208175(TRPM4)

HHV:	120242458(TRPM4)

BTA:	100295930(TRPM4)

BOM:	102275979(TRPM4)

BIU:	109571964(TRPM4)

BBUB:

102415054(TRPM4)

BBIS:

104995726(TRPM4)

CHX:	102182435(TRPM4)

OAS:	101110084(TRPM4)

BTAX:

128063199(TRPM4)

CSUM:

138095927(TRPM4)

ODA:	120872148(TRPM4)

CCAD:

122421019(TRPM4)

MREE:

136161534(TRPM4)

OVR:	110132354(TRPM4)

MBEZ:

129546556(TRPM4)

SSC:	102167071(TRPM4)

CFR:	102519427(TRPM4)

CBAI:

105062622(TRPM4)

CDK:	105100221(TRPM4)

VPC:	102527850(TRPM4)

BACU:

102998468(TRPM4)

BMUS:

118885562(TRPM4)

LVE:	103090686(TRPM4)

OOR:	101288314(TRPM4)

LALB:

132509108(TRPM4)

DLE:	111180629(TRPM4)

PCAD:

102979058 114484773

PSIU:

116743574(TRPM4)

NASI:

112415280(TRPM4)

ECB:	102148867(TRPM4)

EPZ:	103553333(TRPM4)

EAI:	106838280(TRPM4)

MYB:	102238623(TRPM4)

MYD:	102774002(TRPM4)

MMYO:

118655379(TRPM4)

MLF:

102439530

MDT:	132216608(TRPM4)

MYUM:

138999777(TRPM4)

PKL:	118712138(TRPM4)

EFUS:

103297772(TRPM4)

MNA:	107531894(TRPM4)

DRO:	112310071(TRPM4)

AJM:	119046019(TRPM4)

PDIC:

114511484(TRPM4)

PHAS:

123830241(TRPM4)

MMF:	118639498(TRPM4)

PPAM:

129082911(TRPM4)

HAI:	109391100(TRPM4)

RFQ:	117035139(TRPM4)

PALE:

102883437(TRPM4)

PGIG:

120606942(TRPM4)

RAY:	107498826(TRPM4)

MJV:	108400305(TRPM4)

TOD:	119248673(TRPM4)

SARA:

101539466(TRPM4)

SFUM:

130043581(TRPM4)

SETR:

126027184(TRPM4)

LAV:	100671543(TRPM4)

TMU:

101354438

DNM:	101422147(TRPM4)

GAS:	123239807(TRPM4)

SHR:	100926654(TRPM4)

AFZ:

127556542

PCW:	110219984(TRPM4)

TVP:	118837400(TRPM4)

OAA:	100077318(TRPM4)

TACU:

119933239(TRPM4)

ASN:	112548052(TRPM4)

AMJ:	102568344(TRPM4)

CPOO:

109320797(TRPM4)

CMY:	114018698(TRPM4)

CCAY:

125628447(TRPM4) 125628864

DCC:	119847178(TRPM4)

CPIC:

101945681 101949979

CABI:

116817986

MRV:	120388385(TRPM4)

ACS:	100565319(trpm4)

ASAO:

132778091(TRPM4)

PVT:

110079168

SUND:

121935448(TRPM4)

PBI:	103051458(TRPM4)

PMUR:

107282405(TRPM4)

CTIG:

120315601(TRPM4)

TSR:	106548178(TRPM4)

PGUT:

117665005(TRPM4)

APRI:

131197573(TRPM4)

PTEX:

113442835(TRPM4)

NSS:	113413403(TRPM4)

VKO:	123030509(TRPM4)

PMUA:

114581974(TRPM4)

PRAF:

128400513(TRPM4)

ZVI:	118094397(TRPM4)

HCG:	128331308(TRPM4)

GJA:

107119267

STOW:

125444854(TRPM4)

EMC:	129340238(TRPM4)

XLA:	108697268 398685(trpm4.L)

XTR:	100491327(trpm4)

NPR:	108793416(TRPM4)

RTEM:

120916539(TRPM4)

BBUF:

121002112(TRPM4)

BGAR:

122926688(TRPM4)

PWL:

138246356

MUO:	115466606(TRPM4)

GSH:	117367711 117368704

DRE:	100004946(trpm4a) 102659286(trpm4b3) 799647(trpm4b.2)

SRX:	107708888 107729419 107730751 107732162

SANH:

107654014 107658421 107664598 107689664

SGH:	107554101 107557378 107583009 107598633

CCAR:

109058655 109091872

CAUA:

113045677 113047145 113111985 113111986

CGIB:

127949840 127953799

PTET:

122333021(trpm4a)

LROH:

127163524(trpm4a)

OMC:	131537690(trpm4a)

PPRM:

120470402 120489764(trpm4a)

RKG:	130088469(trpm4a)

MAMB:

125255190 125255191 125256049 125277326(trpm4a)

CIDE:

127508012

CERY:

137007508 137007675 137017602(trpm4a)

MASI:

127451799 127451800

TROS:

130561895(trpm4a)

TDW:	130426122(trpm4a) 130438901

MANU:

129436047(trpm4a)

PDAB:

135760280(trpm4a) 135768013

IPU:	108274106 108280300(trpm4a)

IFU:

128616880

PHYP:

113525004 113527265

SMEO:

124388985 124397107(trpm4a)

TFD:	113648545(trpm4a) 113653572

TVC:	132841562 132860981(trpm4a)

CGAR:

128541223 128544645(trpm4a)

NGRA:

132868974(trpm4a) 132898038

TRN:	134300096(trpm4a) 134321089

AMEX:

103041664(trpm4a) 103047479

CMAO:

118800495(trpm4a) 118809733

EEE:	113568647 113580261 113590847

CHAR:

105888533 105898513 105898514 105909790

SPIL:

134069666 134076907(trpm4a)

TRU:

101061927

TFS:

130523706

TNG:	GSTEN00028287G001

LCO:	104935558 104938637

NCC:

TBEN:

CGOB:

PGEO:

GACU:

EMAC:

ELY:	117247069 117267749(trpm4a)

EFO:	125878800(trpm4a) 125881059

PLEP:

121956257(trpm4a) 121958632

SLUC:

ECRA:

ESP:

PFLV:

GAT:	120819058 120827991(trpm4a)

PPUG:

119212579 119212580 119220088(trpm4a)

AFB:	129090982 129098547(trpm4a)

CLUM:

117734906(trpm4a) 117748842

PSWI:

130188076 130203840

CANA:

137789441 137799036(trpm4a)

CVE:	137882491(trpm4a)

MSAM:

119915746 119919146(trpm4a)

SCHU:

122868140 122868978(trpm4a)

CUD:	121503372 121503978 121503979(trpm4a) 121513481 121528799

SPUL:

138593420 138602633(trpm4a)

LMIX:

132954672(trpm4a) 132955232

ALAT:

119009592 119015562(trpm4a)

ASTR:

137588742

MZE:	101467266 101467560 101467864 101472910

ONL:	100703227 102075974 109194528 109203256

OAU:	116315015 116315018 116319842 116319905 116319906

OLA:	101156498 101158642

OML:	112146902(trpm4a) 112154157

CSAI:

133418933 133422777(trpm4a)

XMA:	102222653 102230334

XCO:	114148589 114156005

XHE:	116727652 116735002

PRET:

PFOR:

PLAI:

PMEI:

GAF:	122821751(trpm4a) 122823581

PPRL:

129354932(trpm4a) 129377770

CVG:	107097223 107104313

CTUL:

119771978 119777612

GMU:	124864702 124875662

NFU:	107387988 107387989 107391796

KMR:	108237202 108250027(trpm4a)

ALIM:

106517445 106517446 106526389

NWH:	119421957(trpm4a) 119423477 119423970

AOCE:

111569212 111584597

EJA:	138202028 138215483(trpm4a)

BFRE:

138616968 138627700(trpm4a)

MCEP:

124998367(trpm4a) 125022328

CSEM:

103382033 103393520

POV:

109642330

SSEN:

122759332 122785332

SSOE:

131448437 131475402(trpm4a)

HHIP:

HSP:

PPLT:

SMAU:

LCF:	108884446 108898511(trpm4a)

SDU:	111219808 111227956

SLAL:

111655629 111658723

XGL:	120783688(trpm4a) 120794258

HCQ:	109523944 109524744

SSCV:

125983973(trpm4a) 125990901

SBIA:

133495590 133514647(trpm4a)

PEE:	133395241 133414664(trpm4a)

PTAO:

133465597(trpm4a) 133469815

BPEC:

110159599

MALB:

109963622 109964685

BSPL:

114846319 114860390 114860391(trpm4a)

SJO:	128378525(trpm4a) 128381420

SSCO:

134000074(trpm4a) 134003634

GMH:	115531293 115558203

SASA:

106579418 106600670 106600699 106600700

STRU:

115162698 115170764 115170765 115171552

OTW:	112235559 112251528 112251554 112259040

OMY:	110491797 110538664 110539078(trpm4a) 110539079

OGO:	123999576(trpm4a) 124000766 124048535

ONE:	115106748 115109989 115109990

OKI:	109865191 109880757 109893086 109893126

OKE:	118363680 118374088 118384257(trpm4a) 118384258

OMM:	135504738 135555957 135555959(trpm4a)

SALP:

111978603 112071146

SNH:	120032868 120043945 120044050 120045820

CCLU:

121550302 121550784 121568622 121572036 123481198 123486183

ELS:	105006325 105030609 105031629 105031630

SFM:	108925154 108941646

PKI:	111836835 111851298

AANG:

118216731(trpm4a) 118221647

AROT:

135244060(trpm4a) 135247990

CCOG:

133115384(trpm4a) 133121513

LOC:	102698288(trpm4)

PSPA:

121305880(trpm4a)

PSEX:

120541886(trpm4a)

LCM:

102365897

RTP:	109926408(trpm4a)

CPLA:

122542213(trpm4a)

HOC:	132831252(trpm4a)

LERI:

129713963

PMRN:

116945634(TRPM5)

LRJ:

HRF:

HASI:

HCRA:

CANU:

CVN:	111117338 111136379 111137014

OED:

AIRR:

MAEA:

LLON:

Reference

PMID:12799367

Authors

Nilius B, Prenen J, Droogmans G, Voets T, Vennekens R, Freichel M, Wissenbach U, Flockerzi V

Title

Voltage dependence of the Ca2+-activated cation channel TRPM4.

Journal

J Biol Chem 278:30813-20 (2003)
DOI:10.1074/jbc.M305127200

Sequence

[hsa:54795]

LinkDB

DBGET integrated database retrieval system