KEGG   PATHWAY: omy04060
Entry
omy04060                    Pathway                                
Name
Cytokine-cytokine receptor interaction - Oncorhynchus mykiss (rainbow trout)
Description
Cytokines are soluble extracellular proteins or glycoproteins that are crucial intercellular regulators and mobilizers of cells engaged in innate as well as adaptive inflammatory host defenses, cell growth, differentiation, cell death, angiogenesis, and development and repair processes aimed at the restoration of homeostasis. Cytokines are released by various cells in the body, usually in response to an activating stimulus, and they induce responses through binding to specific receptors on the cell surface of target cells. Cytokines can be grouped by structure into different families and their receptors can likewise be grouped.
Class
Environmental Information Processing; Signaling molecules and interaction
Pathway map
omy04060  Cytokine-cytokine receptor interaction
omy04060

Organism
Oncorhynchus mykiss (rainbow trout) [GN:omy]
Gene
100135804  inh; inhibin precursor [KO:K05500]
100135878  ccl20b; C-C motif chemokine 20b precursor [KO:K14625]
100135914  il8r; interleukin 8 receptor [KO:K05050]
100135919  mstnb; myostatin b precursor [KO:K05497]
100135920  [KO:K05497]
100135968  [KO:K05077]
100135977  [KO:K12672]
100135988  [KO:K05080]
100136024  [KO:K04519]
100136032  il-1rii; interleukin-1 receptor type II precursor [KO:K04387]
100136033  [KO:K05070]
100136034  tnf-alpha; putative tumour necrosis factor alpha [KO:K03156]
100136037  il-1r1; interleukin-1 receptor type 1 precursor [KO:K04386]
100136039  il-8; putative cxc chemokine precursor [KO:K10030]
100136064  tnf; tumor necrosis factor [KO:K03156]
100136075  il11; interleukin-11 precursor [KO:K05417]
100136086  si:dkey-88e18.2; interleukin-12 beta chain precursor [KO:K05425]
100136088  [KO:K22628]
100136089  csf1; macrophage colony-stimulating factor precursor [KO:K05453]
100136090  il15; interleukin 15 precursor [KO:K05433]
100136099  il17d; interleukin-17D precursor [KO:K05492]
100136103  csf3r; granulocyte colony-stimulating factor receptor precursor [KO:K05061]
100136106  ebi3; interleukin-27 subunit beta precursor [KO:K24476]
100136114  il17r; interleukin-17 receptor precursor [KO:K05164]
100136117  ifngr1l; interferon gamma receptor 1 precursor [KO:K05132]
100136126  cxcr3.1; C-X-C chemokine receptor type 3.1 [KO:K04188]
100136133  lep; leptin precursor [KO:K05424]
100136140  [KO:K05414]
100136273  ifn1; interferon a3 precursor [KO:K05414]
100136277  ghr1; growth hormone receptor isoform 1 precursor [KO:K05080]
100136282  [KO:K16621]
100136285  cd4-1; CD4-1 molecule precursor [KO:K06454]
100136313  cxcd2; CXC chemokine d2 precursor [KO:K05416]
100136316  tnfsf13b; tumor necrosis factor ligand superfamily member 13B [KO:K05476]
100136317  [KO:K04721]
100136318  balm; BAFF and APRIL-like molecule [KO:K05476]
100136319  light; TNF superfamily member 14 [KO:K05477]
100136320  [KO:K05473]
100136340  mstn2a; myostatin 2a precursor [KO:K05497]
100136609  prlra; prolactin receptor precursor [KO:K05081]
100136637  [KO:K05143]
100136639  il20ra; interleukin 20 receptor, alpha precursor [KO:K05136]
100136640  il-18; interleukin 18 [KO:K05482]
100136642  il-17a; interleukin 17A precursor [KO:K05489]
100136643  ifng; interferon, gamma precursor [KO:K04687]
100136646  il21r; interleukin-21 receptor precursor [KO:K05071]
100136649  cxcr3.2; C-X-C chemokine receptor type 3-2 isoform 1 [KO:K04188]
100136689  il6; interleukin-6 precursor [KO:K05405]
100136698  cd40l; TNF superfamily member 5 [KO:K03161]
100136706  tnfsf13; tumor necrosis factor ligand superfamily member 13 [KO:K05475]
100136733  gh1; somatotropin-1 precursor [KO:K05438]
100136734  gh2; somatotropin-2 precursor [KO:K05438]
100136774  [KO:K13375]
100136789  ghr; growth hormone receptor precursor [KO:K05080]
100136792  prl; prolactin precursor [KO:K05439]
100136835  il10; interleukin-10 precursor [KO:K05443]
100136949  [KO:K05090] [EC:2.7.10.1]
100136950  [KO:K05090] [EC:2.7.10.1]
100170204  [KO:K12672]
100170214  gdf9; growth/differentiation factor 9 isoform X1 [KO:K22673]
100286821  ifn5; type I interferon 5 precursor [KO:K05414]
100301634  [KO:K12672]
100301644  ifngr2a; interferon gamma receptor 2a precursor [KO:K05133]
100301655  actriib; activin receptor IIB precursor [KO:K13596] [EC:2.7.11.30]
100301673  ifn3; type I interferon 3 precursor [KO:K05414]
100301675  ifngamma2; interferon gamma 2 [KO:K04687]
100301676  ifn2; type I interferon 2 precursor [KO:K05414]
100301860  ccl13; small inducible cytokine A13 isoform X1 [KO:K21097]
100302641  il-22; interleukin 22 precursor [KO:K05445]
100302642  il2; interleukin 2 precursor [KO:K05433]
100305279  tnr5; tumor necrosis factor receptor superfamily member 5 [KO:K05152]
100462681  il17c1; interleukin 17C1 precursor [KO:K05491]
100462682  il17c2; interleukin 17C2 precursor [KO:K05491]
100499593  m17; IL-6 subfamily cytokine M17 precursor [KO:K24382]
100499621  il19l; interleukin 19 like precursor [KO:K22667]
100653437  il21; interleukin-21 precursor [KO:K05434]
100653445  il4r2; IL-4 receptor-2 precursor [KO:K05071]
100653446  il13ra1a; IL-13 receptor-alpha-1-a precursor [KO:K05076]
100653447  il13ra1b; IL-13 receptor-alpha-1-b precursor [KO:K05076]
100653455  [KO:K05058]
100653479  il10b; IL-10b protein precursor [KO:K05443]
100653488  il13ra2b; IL-13 receptor-alpha-2-b precursor [KO:K05077]
100873160  il34; interleukin-34 precursor [KO:K22633]
101268906  il2rb2; interleukin-2 receptor beta chain-2 precursor [KO:K05069]
101268907  il2rb; interleukin-2 receptor subunit beta precursor [KO:K05069]
101268908  il2rc2; interleukin-2 receptor gamma chain-2 precursor [KO:K05070]
101268915  gp130; interleukin 6 signal transducer GP130 protein precursor [KO:K05060]
101268931  cxcl8c; chemokine CXCL8c precursor [KO:K05416]
101268932  cxcf1a; chemokine CXCF1a precursor [KO:K05416]
101268934  cxcl12a; chemokine CXCL12a precursor [KO:K10031]
101268935  cxcl13; chemokine CXCL13 precursor [KO:K10032]
101268936  cxcl14; C-X-C motif chemokine 14 precursor [KO:K10033]
101268942  tgfb1a; transforming growth factor, beta 1a precursor [KO:K13375]
101268944  tgfr2; TGF receptor-2 precursor [KO:K04388] [EC:2.7.11.30]
101268945  [KO:K05072]
101268946  il10r1; IL-10 receptor-1 precursor [KO:K05134]
101268947  [KO:K05136]
101268948  crfb4; cytokine receptor family member b4 precursor [KO:K05135]
101268949  crfb5; cytokine receptor family member b5 precursor [KO:K05135]
101268950  cd40; tumor necrosis factor receptor superfamily member 5 precursor [KO:K03160]
101268951  [KO:K03160]
101268957  [KO:K05135]
101268960  [KO:K04182]
101268967  il6r; interleukin-6 receptor subunit alpha precursor [KO:K05055]
101268968  cxcl12b; chemokine CXCL12b precursor [KO:K10031]
101268979  il1rl1; interleukin 1 receptor-like 1 (ST2L) [KO:K05171]
110485144  [KO:K05414]
110485148  [KO:K05414]
110485223  [KO:K04193]
110485539  [KO:K10031]
110485858  [KO:K05132]
110485869  [KO:K04179]
110485879  [KO:K04179]
110485888  [KO:K04180]
110485902  [KO:K04182]
110486123  [KO:K04738]
110486324  [KO:K05075]
110486479  epor; erythropoietin receptor [KO:K05079]
110486699  [KO:K02583]
110486729  [KO:K05477]
110486918  [KO:K05060]
110487734  clcf1; uncharacterized protein clcf1 [KO:K05421]
110487867  tnfa; tumor necrosis factor [KO:K03156]
110488319  [KO:K05143]
110488555  [KO:K26541]
110488575  [KO:K10033]
110488745  [KO:K03161]
110489077  tgfb5; transforming growth factor beta-2 proprotein [KO:K13376]
110489166  [KO:K22673]
110489282  [KO:K16622]
110489482  [KO:K05425]
110489589  [KO:K05147]
110489618  [KO:K04721]
110489762  bmp6; bone morphogenetic protein 6 [KO:K16620]
110489797  tgfbr1b; TGF-beta receptor type-1 isoform X2 [KO:K04674] [EC:2.7.11.30]
110489843  [KO:K20012]
110489889  [KO:K04184]
110489965  ackr4b; atypical chemokine receptor 4b [KO:K04186]
110490008  inhbaa; inhibin subunit beta Aa [KO:K04667]
110490048  [KO:K04723]
110490140  [KO:K13376]
110490348  [KO:K05074]
110490587  lepb; leptin b [KO:K05424]
110490693  [KO:K05164]
110491122  [KO:K16621]
110491127  [KO:K05168]
110491436  [KO:K05503]
110491438  [KO:K22674]
110491444  [KO:K21283]
110491449  [KO:K05150]
110491742  ngfrb; nerve growth factor receptor b [KO:K02583]
110491862  [KO:K05143]
110491966  [KO:K13567] [EC:2.7.11.30]
110491967  acvrl1; serine/threonine-protein kinase receptor R3 [KO:K13594] [EC:2.7.11.30]
110492146  [KO:K05146]
110492331  [KO:K05165]
110492428  wu:fl23c11; LOW QUALITY PROTEIN: interleukin-17 receptor C [KO:K05166]
110492884  [KO:K05075]
110492888  ccr10; C-C chemokine receptor type 10 [KO:K04182]
110492907  [KO:K05426]
110493526  [KO:K05496]
110493590  ifngr1; interferon gamma receptor 1 isoform X1 [KO:K05132]
110493709  [KO:K05063]
110493841  [KO:K04664]
110494031  il17rc; uncharacterized protein il17rc isoform X1 [KO:K05166]
110494206  [KO:K22679]
110494313  [KO:K13567] [EC:2.7.11.30]
110494536  [KO:K16621]
110494628  [KO:K05141]
110494776  [KO:K22687]
110495069  [KO:K05069]
110495071  [KO:K05069]
110495072  [KO:K05069]
110495073  [KO:K05069]
110495196  [KO:K05142]
110495453  [KO:K05050]
110495748  acvr1l; activin receptor type-1 isoform X2 [KO:K04675] [EC:2.7.11.30]
110495886  [KO:K22687]
110495930  [KO:K04670] [EC:2.7.11.30]
110496033  [KO:K04388] [EC:2.7.11.30]
110496059  gdf6b; growth/differentiation factor 6-B [KO:K20012]
110496162  [KO:K16622]
110496258  [KO:K05143]
110496727  [KO:K03156]
110496949  [KO:K05405]
110497002  [KO:K05050]
110497745  il17a/f1; interleukin 17a/f1 [KO:K05494]
110497765  bmp4; bone morphogenetic protein 4 [KO:K04662]
110497772  [KO:K20013]
110497921  tgfb3; transforming growth factor beta-3 proprotein [KO:K13377]
110498070  [KO:K04181]
110498449  [KO:K05433]
110499035  [KO:K22674]
110499036  [KO:K22670]
110499048  [KO:K05150]
110499283  [KO:K05132]
110499371  bmp5; bone morphogenetic protein 5 [KO:K04663]
110499590  [KO:K05153]
110500081  [KO:K05164]
110500519  epoa; erythropoietin isoform X1 [KO:K05437]
110500556  il13ra1; interleukin-13 receptor subunit alpha-1 [KO:K05076]
110500573  [KO:K05474]
110500589  [KO:K05076]
110500745  [KO:K05408]
110500768  rell1; RELT-like protein 1 isoform X1 [KO:K26541]
110501285  [KO:K05050]
110501419  ifngr2b; uncharacterized protein ifngr2b [KO:K05133]
110501422  [KO:K05135]
110501423  [KO:K05135]
110501424  [KO:K05131]
110501518  [KO:K04675] [EC:2.7.11.30]
110501520  [KO:K13568] [EC:2.7.11.30]
110501538  [KO:K06454]
110501543  [KO:K04189]
110501640  [KO:K04304]
110501712  tnfsf11; tumor necrosis factor ligand superfamily member 11 [KO:K05473]
110501718  [KO:K05162]
110501778  [KO:K04388] [EC:2.7.11.30]
110501797  [KO:K22687]
110501883  [KO:K04670] [EC:2.7.11.30]
110501935  [KO:K22672]
110502091  [KO:K04386]
110502234  [KO:K10031]
110502384  [KO:K04673] [EC:2.7.11.30]
110502471  [KO:K04390]
110502694  [KO:K04663]
110502937  [KO:K13072]
110503290  [KO:K04190]
110503302  [KO:K21283]
110503453  [KO:K05406]
110503477  [KO:K05156]
110504009  [KO:K05155]
110504093  [KO:K06854]
110504156  [KO:K05421]
110504334  [KO:K05489]
110504402  rell2; uncharacterized protein DKFZp434B061 [KO:K26541]
110504548  [KO:K05476]
110504616  [KO:K05425]
110504828  [KO:K05090] [EC:2.7.10.1]
110504983  [KO:K04671] [EC:2.7.11.30]
110505089  [KO:K05434]
110505380  [KO:K04181]
110505545  [KO:K13377]
110505609  nradd; tumor necrosis factor receptor superfamily member 16 isoform X1 [KO:K02583]
110505692  [KO:K20013]
110505700  [KO:K04662]
110505720  [KO:K05494]
110507263  [KO:K05406]
110507419  bmp16; bone morphogenetic protein 16 [KO:K21283]
110507445  [KO:K05134]
110507838  [KO:K05155]
110507854  [KO:K05438]
110508013  [KO:K05156]
110508205  ccl20a.3; C-C motif chemokine 20a.3 [KO:K14625]
110508214  [KO:K05504]
110508456  [KO:K14625]
110508669  [KO:K04674] [EC:2.7.11.30]
110508673  [KO:K04179]
110508802  thpo; uncharacterized protein thpo isoform X1 [KO:K06854]
110508867  [KO:K04186]
110508876  [KO:K05406]
110509048  [KO:K05417]
110509110  [KO:K04184]
110509121  inhbab; inhibin subunit beta Ab [KO:K04667]
110509178  [KO:K04193]
110509528  [KO:K03158]
110509537  [KO:K03158]
110509538  [KO:K05060]
110509557  [KO:K04519]
110509570  [KO:K05144]
110509576  [KO:K05144]
110509702  [KO:K04722]
110509752  [KO:K04666]
110509876  [KO:K05512]
110509923  [KO:K05437]
110510485  [KO:K10032]
110510500  [KO:K10032]
110510821  [KO:K05414]
110511235  [KO:K05414]
110511354  [KO:K05174]
110511378  bmpr2b; bone morphogenetic protein receptor type-2 [KO:K04671] [EC:2.7.11.30]
110512703  [KO:K04179]
110512719  [KO:K04180]
110513456  [KO:K05069]
110513917  [KO:K05081]
110514317  [KO:K04188]
110514657  [KO:K16595]
110514811  [KO:K05408]
110515024  [KO:K04666]
110515104  [KO:K21097]
110515522  [KO:K02582]
110515790  [KO:K16595]
110515815  [KO:K04666]
110516585  [KO:K04189]
110516630  [KO:K21097]
110517168  [KO:K05414]
110517304  [KO:K16621]
110517705  [KO:K05414]
110517824  [KO:K05414]
110518225  [KO:K10032]
110518401  tgfbr2b; TGF-beta receptor type-2 [KO:K04388] [EC:2.7.11.30]
110518755  [KO:K20012]
110518831  [KO:K05173]
110518912  [KO:K05491]
110519367  tgfb2; transforming growth factor beta-2 proprotein [KO:K13376]
110520024  [KO:K04189]
110520051  [KO:K13568] [EC:2.7.11.30]
110520052  [KO:K04675] [EC:2.7.11.30]
110520098  [KO:K22633]
110520169  [KO:K05171]
110520170  [KO:K05171]
110520186  acvr2aa; activin receptor type-2A isoform X1 [KO:K04670] [EC:2.7.11.30]
110520286  [KO:K22687]
110520304  tgfbr2l; TGF-beta receptor type-2 [KO:K04388] [EC:2.7.11.30]
110520326  zmp:0000000936; interleukin-1 receptor type 1 [KO:K04386]
110520359  [KO:K05162]
110520367  [KO:K05473]
110520437  [KO:K04304]
110520605  [KO:K05050]
110520635  [KO:K05135]
110520638  [KO:K05131]
110520706  [KO:K05148]
110521615  [KO:K04389]
110521795  [KO:K05062]
110521821  [KO:K05082]
110521934  [KO:K05439]
110522289  [KO:K05157]
110522446  [KO:K21283]
110522508  [KO:K04181]
110522636  [KO:K13377]
110522754  [KO:K05060]
110522811  il1b; interleukin-1 beta [KO:K04519]
110522929  bmpr1bb; bone morphogenetic protein receptor, type IBb isoform X1 [KO:K13578] [EC:2.7.11.30]
110523172  [KO:K22630]
110523275  [KO:K05478]
110523488  tnfrsfa; tumor necrosis factor receptor superfamily member 10B [KO:K04722]
110523543  ndr1; nodal-related 1 [KO:K04666]
110523665  [KO:K05512]
110523771  [KO:K22670]
110523781  il7r; interleukin-7 receptor subunit alpha isoform X1 [KO:K05072]
110524073  [KO:K04193]
110524147  [KO:K05063]
110524217  ccl44; C-C motif chemokine 17 [KO:K21083]
110524219  [KO:K13072]
110524306  [KO:K04665]
110524480  il23r; interleukin-23 receptor [KO:K05064]
110524481  il12rb2; interleukin-12 receptor subunit beta-2 isoform X1 [KO:K05064]
110524498  faslg; tumor necrosis factor ligand superfamily member 6 [KO:K04389]
110524724  [KO:K05062]
110524756  [KO:K05082]
110524910  [KO:K05480]
110524928  [KO:K04671] [EC:2.7.11.30]
110524930  [KO:K05056]
110525015  [KO:K04389]
110525193  ccl19a.1; C-C motif chemokine 19a.1 [KO:K05512]
110525228  lifra; LIF receptor subunit alpha a [KO:K05058]
110525233  bmpr1ba; bone morphogenetic protein receptor type-1B [KO:K13578] [EC:2.7.11.30]
110525444  prlrb; prolactin receptor b isoform X1 [KO:K05081]
110525714  [KO:K04666]
110525870  [KO:K22670]
110525895  hdr; hematopoietic death receptor isoform X1 [KO:K04722]
110525961  ccl27a; C-C motif chemokine 27a [KO:K05513]
110525975  ghra; growth hormone receptor a [KO:K05080]
110526144  osmr; leukemia inhibitory factor receptor isoform X1 [KO:K05058]
110526988  [KO:K22628]
110527107  gdf5; growth/differentiation factor 5 [KO:K04664]
110527108  ngfb; nerve growth factor [KO:K02582]
110527377  [KO:K05473]
110527500  [KO:K22687]
110527542  [KO:K04670] [EC:2.7.11.30]
110527592  [KO:K05130]
110527696  [KO:K22687]
110527713  [KO:K04673] [EC:2.7.11.30]
110527793  si:ch73-361p23.3; tumor necrosis factor receptor superfamily member 9 [KO:K05142]
110527838  tnfrsf1b; tumor necrosis factor receptor superfamily member 1B [KO:K05141]
110528117  [KO:K13567] [EC:2.7.11.30]
110528233  [KO:K22679]
110528367  csf1a; uncharacterized protein csf1a [KO:K05453]
110528435  [KO:K05166]
110528842  [KO:K05500]
110528876  [KO:K04675] [EC:2.7.11.30]
110529004  [KO:K04390]
110529145  [KO:K21283]
110529294  [KO:K13377]
110529296  il17a/f3; interleukin 17a/f3 [KO:K05494]
110529670  tnfrsf21; tumor necrosis factor receptor superfamily member 21 [KO:K05157]
110529872  [KO:K21283]
110529952  crfb16; cytokine receptor family member B16 isoform X1 [KO:K05137]
110529980  ccr9; chemokine receptor [KO:K04184]
110529989  [KO:K04667]
110530126  [KO:K05504]
110530161  [KO:K04186]
110530382  [KO:K04179]
110530388  [KO:K04674] [EC:2.7.11.30]
110530627  [KO:K04189]
110530632  [KO:K05066]
110530649  [KO:K14625]
110530729  [KO:K14625]
110530731  [KO:K14625]
110530865  [KO:K04193]
110531007  [KO:K14625]
110531045  [KO:K13596] [EC:2.7.11.30]
110531086  [KO:K04181]
110531412  bmp15; bone morphogenetic protein 15 [KO:K05498]
110531655  [KO:K05437]
110531703  [KO:K05474]
110531978  [KO:K05168]
110532217  [KO:K05160]
110532464  [KO:K05146]
110532509  gdf10a; growth/differentiation factor 10 [KO:K22674]
110532699  [KO:K13567] [EC:2.7.11.30]
110532700  [KO:K13594] [EC:2.7.11.30]
110532760  [KO:K05152]
110532762  [KO:K05152]
110532763  [KO:K05152]
110532768  [KO:K05152]
110532769  [KO:K05152]
110532774  [KO:K05152]
110533299  ngfa; neurotrophin-7 [KO:K02582]
110533322  [KO:K05425]
110533775  [KO:K22629]
110533836  [KO:K05163]
110533846  [KO:K05480]
110533936  [KO:K05437]
110534057  [KO:K13375]
110534179  [KO:K05090] [EC:2.7.10.1]
110534210  si:dkey-92i15.4; uncharacterized protein si:dkey-92i15.4 [KO:K22628]
110534909  smtlb; somatolactin beta [KO:K05438]
110535204  [KO:K04674] [EC:2.7.11.30]
110535239  [KO:K16620]
110535274  [KO:K13596] [EC:2.7.11.30]
110535418  tnfrsf11a; tumor necrosis factor receptor superfamily member 11A isoform X1 [KO:K05147]
110535572  [KO:K04667]
110535609  [KO:K04186]
110535665  [KO:K04184]
110536068  [KO:K22628]
110536087  [KO:K04666]
110536280  [KO:K04722]
110536401  [KO:K04519]
110536449  [KO:K16062]
110536453  [KO:K12672]
110536502  [KO:K05496]
110536815  [KO:K13578] [EC:2.7.11.30]
110536847  [KO:K05155]
110536851  il11ra; interleukin-11 receptor subunit alpha isoform X1 [KO:K05056]
110537151  [KO:K22670]
110537176  [KO:K24382]
110537277  [KO:K05480]
110537287  eda2r; uncharacterized protein eda2r isoform X1 [KO:K05163]
110537349  [KO:K22629]
110537622  [KO:K04188]
110537629  [KO:K04188]
110537792  il12bb; interleukin-12 subunit beta [KO:K05425]
110537852  [KO:K05060]
110538012  [KO:K04738]
110538043  [KO:K05414]
110538045  [KO:K05414]
110538046  [KO:K05414]
110538047  [KO:K05414]
110538048  [KO:K05414]
110538049  [KO:K05414]
110538051  ifnphi1; interferon a3 [KO:K05414]
110538053  [KO:K05414]
110538058  [KO:K05414]
110538059  [KO:K05414]
110538077  [KO:K05423]
110538260  [KO:K05071]
110538267  [KO:K05075]
110538308  [KO:K05079]
110538491  [KO:K10030]
110538653  [KO:K02583]
110538937  [KO:K05414]
110538938  [KO:K05414]
110538940  [KO:K05414]
110538941  [KO:K05414]
110538942  [KO:K05414]
110539157  [KO:K05414]
110539158  [KO:K05414]
110539160  [KO:K05414]
110539161  [KO:K05414]
118936246  [KO:K05055]
118936254  tgfb1a; transforming growth factor, beta 1a [KO:K13375]
118936262  [KO:K05414]
118936363  [KO:K05414]
118936372  [KO:K05071]
118936417  [KO:K05414]
118936566  [KO:K05050]
118936649  [KO:K04662]
118937412  [KO:K12672]
118937413  [KO:K12672]
118937616  cntfr; ciliary neurotrophic factor receptor subunit alpha [KO:K05059]
118937708  [KO:K05414]
118937709  [KO:K05414]
118937711  [KO:K05414]
118937713  [KO:K05414]
118937891  [KO:K05414]
118937892  [KO:K05414]
118937893  [KO:K05414]
118938066  [KO:K05414]
118938067  [KO:K05414]
118938165  [KO:K05477]
118938265  [KO:K05414]
118938266  [KO:K05414]
118938267  [KO:K05414]
118938268  [KO:K05414]
118938269  [KO:K05414]
118938270  [KO:K05414]
118938271  [KO:K05414]
118938272  [KO:K05414]
118938273  [KO:K05414]
118938274  [KO:K05414]
118938457  [KO:K05151]
118938789  [KO:K14625]
118938790  [KO:K14625]
118938931  [KO:K05439]
118938933  [KO:K04687]
118940077  [KO:K05477]
118940497  [KO:K02582]
118941082  [KO:K05173]
118941094  [KO:K04304]
118941101  [KO:K05050]
118942949  ccl36.1; C-C motif chemokine 36.1 [KO:K05408]
118943005  [KO:K05439]
118943614  [KO:K22672]
118944138  [KO:K04181]
118944444  [KO:K21097]
118944470  [KO:K21097]
118946468  [KO:K05417]
118951907  [KO:K05414]
118951912  [KO:K05414]
118951913  [KO:K05414]
118951914  [KO:K05414]
118951915  [KO:K05414]
118951916  [KO:K05414]
118951917  [KO:K05414]
118964552  [KO:K05059]
118964815  [KO:K10032]
118965241  [KO:K04304]
118965334  [KO:K05174]
118965336  [KO:K05081]
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Cytokines and chemokines: At the crossroads of cell signalling and inflammatory disease.
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Biochim Biophys Acta 1843:2563-2582 (2014)
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PMID:21106488
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Evolutionary divergence and functions of the human interleukin (IL) gene family.
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Hum Genomics 5:30-55 (2010)
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Akdis M, Aab A, Altunbulakli C, Azkur K, Costa RA, Crameri R, Duan S, Eiwegger T, Eljaszewicz A, Ferstl R, Frei R, Garbani M, Globinska A, Hess L, Huitema C, Kubo T, Komlosi Z, Konieczna P, Kovacs N, Kucuksezer UC, Meyer N, Morita H, Olzhausen J, O'Mahony L, Pezer M, Prati M, Rebane A, Rhyner C, Rinaldi A, Sokolowska M, Stanic B, Sugita K, Treis A, van de Veen W, Wanke K, Wawrzyniak M, Wawrzyniak P, Wirz OF, Zakzuk JS, Akdis CA
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Interleukins (from IL-1 to IL-38), interferons, transforming growth factor beta, and TNF-alpha: Receptors, functions, and roles in diseases.
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J Allergy Clin Immunol 138:984-1010 (2016)
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PMID:15500860
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Boulanger MJ, Garcia KC
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Shared cytokine signaling receptors: structural insights from the gp130 system.
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Adv Protein Chem 68:107-46 (2004)
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PMID:16034365
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Interleukin-1 and neuronal injury.
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Nat Rev Immunol 5:629-40 (2005)
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PMID:23847622
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Opposing Functions of Classic and Novel IL-1 Family Members in Gut Health and Disease.
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Front Immunol 4:181 (2013)
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PMID:21349428
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Iwakura Y, Ishigame H, Saijo S, Nakae S
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Functional specialization of interleukin-17 family members.
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Immunity 34:149-62 (2011)
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PMID:17530315
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Fischer P, Hilfiker-Kleiner D
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Survival pathways in hypertrophy and heart failure: the gp130-STAT3 axis.
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Basic Res Cardiol 102:279-97 (2007)
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The enigmatic cytokine oncostatin m and roles in disease.
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ISRN Inflamm 2013:512103 (2013)
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PMID:18926762
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Structures and biological functions of IL-31 and IL-31 receptors.
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Cytokine Growth Factor Rev 19:347-56 (2008)
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PMID:21155715
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The deubiquitinating enzyme DUB2A enhances CSF3 signalling by attenuating lysosomal routing of the CSF3 receptor.
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Biochem J 434:343-51 (2011)
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The interferons and their receptors--distribution and regulation.
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Immunol Cell Biol 90:483-91 (2012)
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Aggarwal BB
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Signalling pathways of the TNF superfamily: a double-edged sword.
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Nat Rev Immunol 3:745-56 (2003)
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Targeting death and decoy receptors of the tumour-necrosis factor superfamily.
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Nat Rev Cancer 2:420-30 (2002)
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The TGF-beta superfamily in dendritic cell biology.
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Cytokine Growth Factor Rev 26:647-57 (2015)
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Beyond TGFbeta: roles of other TGFbeta superfamily members in cancer.
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Nat Rev Cancer 13:328-41 (2013)
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Promiscuity and specificity in BMP receptor activation.
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FEBS Lett 586:1846-59 (2012)
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KO pathway
ko04060   

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