KEGG   PATHWAY: snh04148
Entry
snh04148                    Pathway                                
Name
Efferocytosis - Salvelinus namaycush (lake trout)
Class
Cellular Processes; Transport and catabolism
Pathway map
snh04148  Efferocytosis
snh04148

Organism
Salvelinus namaycush (lake trout) [GN:snh]
Gene
120040359  caspase-3-like [KO:K02187] [EC:3.4.22.56]
120035095  caspase-3-like [KO:K02187] [EC:3.4.22.56]
120062476  casp3b; caspase-3b [KO:K02187] [EC:3.4.22.56]
120052764  casp3a; caspase-3a [KO:K02187] [EC:3.4.22.56]
120021869  caspase-7-like [KO:K04397] [EC:3.4.22.60]
120026227  caspase-3-like [KO:K04397] [EC:3.4.22.60]
120060921  casp7; caspase-7 [KO:K04397] [EC:3.4.22.60]
120018779  caspase-1-like [KO:K01370] [EC:3.4.22.36]
120042531  uncharacterized protein LOC120042531 [KO:K01370] [EC:3.4.22.36]
120029080  caspase-1-like [KO:K01370] [EC:3.4.22.36]
120036891  uncharacterized protein LOC120036891 [KO:K01370] [EC:3.4.22.36]
120037031  NACHT, LRR and PYD domains-containing protein 1 homolog [KO:K01370] [EC:3.4.22.36]
120051700  uncharacterized protein LOC120051700 [KO:K01370] [EC:3.4.22.36]
120018777  pannexin-1-like [KO:K03443]
120028856  pannexin-1-like [KO:K03443]
120057147  pannexin-1-like [KO:K03443]
120028508  P2Y purinoceptor 2-like [KO:K04269]
120036062  p2ry2.1; P2Y purinoceptor 2 [KO:K04269]
120029041  P2Y purinoceptor 3 [KO:K04272]
120018929  P2Y purinoceptor 12-like [KO:K04298]
120029016  P2Y purinoceptor 12-like [KO:K04298]
120030942  sphingosine kinase 2-like [KO:K04718] [EC:2.7.1.91]
120032730  sphingosine kinase 1-like [KO:K04718] [EC:2.7.1.91]
120044616  sphingosine kinase 2-like [KO:K04718] [EC:2.7.1.91]
120034002  sphingosine kinase 2-like [KO:K04718] [EC:2.7.1.91]
120047263  sphingosine kinase 2-like [KO:K04718] [EC:2.7.1.91]
120065968  sphingosine kinase 1-like [KO:K04718] [EC:2.7.1.91]
120053706  sphingosine 1-phosphate receptor 1-like [KO:K04288]
120054658  sphingosine 1-phosphate receptor 1 [KO:K04288]
120057784  pla2g6; 85/88 kDa calcium-independent phospholipase A2 isoform X1 [KO:K16343] [EC:3.1.1.4]
120030237  phospholipid-transporting ATPase ABCA1-like [KO:K05641]
120048072  phospholipid-transporting ATPase ABCA1-like isoform X1 [KO:K05641]
120048976  phospholipid-transporting ATPase ABCA1-like [KO:K05641]
120034926  phospholipid-transporting ATPase ABCA1-like isoform X1 [KO:K05641]
120061998  phospholipid-transporting ATPase ABCA1-like isoform X1 [KO:K05641]
120052909  phospholipid-transporting ATPase ABCA1-like isoform X1 [KO:K05641]
120054032  abca7; phospholipid-transporting ATPase ABCA1 [KO:K05641]
120019574  probable G-protein coupled receptor 132 [KO:K08426]
120030450  si:dkey-165a24.9; probable G-protein coupled receptor 132 [KO:K08426]
120024361  probable G-protein coupled receptor 132 [KO:K08426]
120023088  adam17a; disintegrin and metalloproteinase domain-containing protein 17a isoform X1 [KO:K06059] [EC:3.4.24.86]
120019620  adam17b; disintegrin and metalloproteinase domain-containing protein 17 [KO:K06059] [EC:3.4.24.86]
120060189  disintegrin and metalloproteinase domain-containing protein 17-like [KO:K06059] [EC:3.4.24.86]
120025369  disintegrin and metalloproteinase domain-containing protein 10-like isoform X1 [KO:K06704] [EC:3.4.24.81]
120036120  disintegrin and metalloproteinase domain-containing protein 10-like [KO:K06704] [EC:3.4.24.81]
120047253  disintegrin and metalloproteinase domain-containing protein 10-like [KO:K06704] [EC:3.4.24.81]
120052330  disintegrin and metalloproteinase domain-containing protein 10-like [KO:K06704] [EC:3.4.24.81]
120053169  si:ch1073-396h14.1; disintegrin and metalloproteinase domain-containing protein 10 [KO:K06704] [EC:3.4.24.81]
120066766  disintegrin and metalloproteinase domain-containing protein 10-like [KO:K06704] [EC:3.4.24.81]
120065469  nuclear factor of activated T-cells, cytoplasmic 2 [KO:K17332]
120059614  nuclear factor of activated T-cells, cytoplasmic 2-like [KO:K17332]
120061102  nuclear factor of activated T-cells, cytoplasmic 2-like [KO:K17332]
120022776  nuclear factor of activated T-cells, cytoplasmic 1-like [KO:K04446]
120031237  nuclear factor of activated T-cells, cytoplasmic 1-like [KO:K04446]
120026743  nuclear factor of activated T-cells, cytoplasmic 1-like [KO:K04446]
120047116  nuclear factor of activated T-cells, cytoplasmic 1-like [KO:K04446]
120048266  nuclear factor of activated T-cells, cytoplasmic 3-like isoform X1 [KO:K17333]
120025379  nuclear factor of activated T-cells, cytoplasmic 3-like [KO:K17333]
120054141  nuclear factor of activated T-cells, cytoplasmic 3-like [KO:K17333]
120066325  nuclear factor of activated T-cells, cytoplasmic 3-like [KO:K17333]
120020635  nuclear factor of activated T-cells, cytoplasmic 4-like [KO:K17334]
120055628  nfatc4; nuclear factor of activated T-cells, cytoplasmic 4 [KO:K17334]
120018310  hypoxia-inducible factor 1-alpha-like isoform X1 [KO:K08268]
120023846  hif1aa; hypoxia inducible factor 1 subunit alpha a [KO:K08268]
120028243  hypoxia-inducible factor 3-alpha-like isoform X1 [KO:K08268]
120060344  hypoxia-inducible factor 1-alpha isoform X1 [KO:K08268]
120039498  aryl hydrocarbon receptor nuclear translocator isoform X1 [KO:K09097]
120039502  aryl hydrocarbon receptor nuclear translocator-like isoform X1 [KO:K09097]
120021333  epob; erythropoietin b isoform X1 [KO:K05437]
120030352  erythropoietin-like isoform X1 [KO:K05437]
120049699  erythropoietin-like [KO:K05437]
120057538  erythropoietin-like [KO:K05437]
120046320  erythropoietin receptor-like [KO:K05079]
120038293  erythropoietin receptor-like [KO:K05079]
120025864  tyrosine-protein kinase JAK2-like isoform X1 [KO:K04447] [EC:2.7.10.2]
120044197  tyrosine-protein kinase JAK2-like [KO:K04447] [EC:2.7.10.2]
120057049  jak2b; tyrosine-protein kinase JAK2 [KO:K04447] [EC:2.7.10.2]
120042809  mitogen-activated protein kinase 1-like [KO:K04371] [EC:2.7.11.24]
120033084  mitogen-activated protein kinase 1-like [KO:K04371] [EC:2.7.11.24]
120037194  mitogen-activated protein kinase 1-like [KO:K04371] [EC:2.7.11.24]
120052722  mitogen-activated protein kinase 1-like [KO:K04371] [EC:2.7.11.24]
120059245  CCAAT/enhancer-binding protein beta-like [KO:K10048]
120061130  CCAAT/enhancer-binding protein beta-like [KO:K10048]
120037108  pparg; peroxisome proliferator-activated receptor gamma isoform X1 [KO:K08530]
120059497  peroxisome proliferator-activated receptor gamma-like isoform X1 [KO:K08530]
120061319  peroxisome proliferator-activated receptor gamma-like [KO:K08530]
120019874  retinoic acid receptor RXR-gamma-A-like [KO:K08524]
120020449  retinoic acid receptor RXR-gamma-A-like isoform X1 [KO:K08524]
120021279  retinoic acid receptor RXR-alpha-A-like isoform X1 [KO:K08524]
120025770  retinoic acid receptor RXR-alpha-A [KO:K08524]
120055828  retinoic acid receptor RXR-gamma-A-like isoform X1 [KO:K08524]
120050470  retinoic acid receptor RXR-alpha-A-like [KO:K08524]
120031524  retinoic acid receptor RXR-beta-A-like isoform X1 [KO:K08524]
120048420  lactadherin-like isoform X1 [KO:K17253]
120048758  lactadherin-like isoform X1 [KO:K17253]
120051645  lactadherin-like [KO:K17253]
120066567  lactadherin-like [KO:K17253]
120040093  growth arrest-specific protein 6-like [KO:K05464]
120051548  gas6; growth arrest-specific protein 6 isoform X1 [KO:K05464]
120029319  mertka; tyrosine-protein kinase Mer [KO:K05117] [EC:2.7.10.1]
120049383  platelet glycoprotein 4-like [KO:K06259]
120032325  platelet glycoprotein 4-like [KO:K06259]
120023096  thrombospondin-1-like [KO:K16857]
120019198  thrombospondin-1-like [KO:K16857]
120024499  thrombospondin-1-like [KO:K16857]
120060229  thrombospondin-1-like [KO:K16857]
120042460  dual specificity mitogen-activated protein kinase kinase 1-like [KO:K04368] [EC:2.7.12.2]
120020580  dual specificity mitogen-activated protein kinase kinase 2-like [KO:K04369] [EC:2.7.12.2]
120056021  map2k2b; dual specificity mitogen-activated protein kinase kinase 2b [KO:K04369] [EC:2.7.12.2]
120052438  dual specificity mitogen-activated protein kinase kinase 2-like isoform X1 [KO:K04369] [EC:2.7.12.2]
120054777  dual specificity mitogen-activated protein kinase kinase 2 [KO:K04369] [EC:2.7.12.2]
120020058  ptgs2a; prostaglandin G/H synthase 2a [KO:K11987] [EC:1.14.99.1]
120055825  prostaglandin G/H synthase 2-like [KO:K11987] [EC:1.14.99.1]
120051921  prostaglandin G/H synthase 2-like [KO:K11987] [EC:1.14.99.1]
120055021  prostaglandin G/H synthase 2-like [KO:K11987] [EC:1.14.99.1]
120019155  prostaglandin E2 receptor EP2 subtype-like [KO:K04259]
120023836  ptger2a; prostaglandin E receptor 2a (subtype EP2) [KO:K04259]
120024433  prostaglandin E2 receptor EP2 subtype-like [KO:K04259]
120059962  prostaglandin E2 receptor EP2 subtype-like [KO:K04259]
120019895  prostaglandin E2 receptor EP4 subtype-like [KO:K04261]
120021825  prostaglandin E2 receptor EP4 subtype-like [KO:K04261]
120026402  prostaglandin E2 receptor EP4 subtype-like [KO:K04261]
120063393  prostaglandin E2 receptor EP4 subtype-like [KO:K04261]
120054031  prostaglandin E2 receptor EP4 subtype-like [KO:K04261]
120054690  prostaglandin E2 receptor EP4 subtype-like [KO:K04261]
120055497  prostaglandin E2 receptor EP4 subtype-like [KO:K04261]
120055542  prostaglandin E2 receptor EP4 subtype-like [KO:K04261]
120023105  DNA (cytosine-5)-methyltransferase 3A-like [KO:K17398] [EC:2.1.1.37]
120042173  DNA (cytosine-5)-methyltransferase 3A-like [KO:K17398] [EC:2.1.1.37]
120060494  DNA (cytosine-5)-methyltransferase 3A-like [KO:K17398] [EC:2.1.1.37]
120039121  cyclic AMP-responsive element-binding protein 1-like isoform X1 [KO:K05870]
120064115  cyclic AMP-responsive element-binding protein 1-like [KO:K05870]
120058353  creb1b; cyclic AMP-responsive element-binding protein 1b isoform X1 [KO:K05870]
120021386  transforming growth factor beta-1 proprotein isoform X1 [KO:K13375]
120028313  tgfb1a; transforming growth factor, beta 1a [KO:K13375]
120056617  transforming growth factor beta-1 proprotein-like isoform X1 [KO:K13375]
120021216  sarcoplasmic/endoplasmic reticulum calcium ATPase 2 [KO:K05853] [EC:7.2.2.10]
120025830  sarcoplasmic/endoplasmic reticulum calcium ATPase 2-like [KO:K05853] [EC:7.2.2.10]
120032619  sarcoplasmic/endoplasmic reticulum calcium ATPase 1-like [KO:K05853] [EC:7.2.2.10]
120033350  sarcoplasmic/endoplasmic reticulum calcium ATPase 1-like [KO:K05853] [EC:7.2.2.10]
120034779  sarcoplasmic/endoplasmic reticulum calcium ATPase 2-like [KO:K05853] [EC:7.2.2.10]
120046392  atp2a1l; ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1, like isoform X1 [KO:K05853] [EC:7.2.2.10]
120056831  sarcoplasmic/endoplasmic reticulum calcium ATPase 1-like [KO:K05853] [EC:7.2.2.10]
120063153  sarcoplasmic/endoplasmic reticulum calcium ATPase 2-like [KO:K05853] [EC:7.2.2.10]
120052719  sarcoplasmic/endoplasmic reticulum calcium ATPase 1-like [KO:K05853] [EC:7.2.2.10]
120052887  sarcoplasmic/endoplasmic reticulum calcium ATPase 2-like [KO:K05853] [EC:7.2.2.10]
120061789  sarcoplasmic/endoplasmic reticulum calcium ATPase 2-like isoform X1 [KO:K05853] [EC:7.2.2.10]
120017633  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X1 [KO:K04515] [EC:2.7.11.17]
120020925  calcium/calmodulin-dependent protein kinase type II subunit beta-like [KO:K04515] [EC:2.7.11.17]
120021507  calcium/calmodulin-dependent protein kinase type II subunit alpha-like isoform X1 [KO:K04515] [EC:2.7.11.17]
120030077  calcium/calmodulin-dependent protein kinase type II subunit gamma-like isoform X1 [KO:K04515] [EC:2.7.11.17]
120030240  calcium/calmodulin-dependent protein kinase type II subunit delta isoform X1 [KO:K04515] [EC:2.7.11.17]
120043972  camk2b1; calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 1 [KO:K04515] [EC:2.7.11.17]
120026217  calcium/calmodulin-dependent protein kinase type II subunit beta-like [KO:K04515] [EC:2.7.11.17]
120046117  calcium/calmodulin-dependent protein kinase type II delta chain-like isoform X1 [KO:K04515] [EC:2.7.11.17]
120046553  calcium/calmodulin-dependent protein kinase type II subunit gamma-like [KO:K04515] [EC:2.7.11.17]
120049576  calcium/calmodulin-dependent protein kinase type II delta chain-like isoform X1 [KO:K04515] [EC:2.7.11.17]
120056652  calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1 [KO:K04515] [EC:2.7.11.17]
120062966  calcium/calmodulin-dependent protein kinase type II subunit beta-like [KO:K04515] [EC:2.7.11.17]
120031745  mitogen-activated protein kinase 12-like isoform X1 [KO:K04441] [EC:2.7.11.24]
120031746  mitogen-activated protein kinase 11-like [KO:K04441] [EC:2.7.11.24]
120049930  mitogen-activated protein kinase 12-like [KO:K04441] [EC:2.7.11.24]
120049931  mitogen-activated protein kinase 11-like [KO:K04441] [EC:2.7.11.24]
120057678  mitogen-activated protein kinase 14A-like isoform X1 [KO:K04441] [EC:2.7.11.24]
120058796  mitogen-activated protein kinase 14A-like [KO:K04441] [EC:2.7.11.24]
120065006  mitogen-activated protein kinase 14A-like isoform X1 [KO:K04441] [EC:2.7.11.24]
120059107  mitogen-activated protein kinase 14A-like isoform X1 [KO:K04441] [EC:2.7.11.24]
120059400  mapk13; mitogen-activated protein kinase 13 [KO:K04441] [EC:2.7.11.24]
120054081  mapk12a; mitogen-activated protein kinase 12 isoform X1 [KO:K04441] [EC:2.7.11.24]
120066420  mitogen-activated protein kinase 12-like isoform X1 [KO:K04441] [EC:2.7.11.24]
120060612  mitogen-activated protein kinase 12-like [KO:K04441] [EC:2.7.11.24]
120060986  mitogen-activated protein kinase 14A isoform X1 [KO:K04441] [EC:2.7.11.24]
120059520  MAP kinase-activated protein kinase 2-like [KO:K04443] [EC:2.7.11.1]
120061372  MAP kinase-activated protein kinase 2-like isoform X1 [KO:K04443] [EC:2.7.11.1]
120017762  polyunsaturated fatty acid 5-lipoxygenase-like [KO:K00461] [EC:1.13.11.34]
120045686  polyunsaturated fatty acid 5-lipoxygenase-like isoform X1 [KO:K00461] [EC:1.13.11.34]
120040140  dual specificity protein phosphatase 7-like [KO:K04459] [EC:3.1.3.16 3.1.3.48]
120031889  dusp16; dual specificity protein phosphatase 16 [KO:K04459] [EC:3.1.3.16 3.1.3.48]
120025863  dual specificity protein phosphatase 4-like [KO:K04459] [EC:3.1.3.16 3.1.3.48]
120032901  dusp5; dual specificity protein phosphatase 5 [KO:K04459] [EC:3.1.3.16 3.1.3.48]
120044985  dual specificity protein phosphatase 4-like [KO:K04459] [EC:3.1.3.16 3.1.3.48]
120062754  dusp2; dual specificity protein phosphatase 2 [KO:K04459] [EC:3.1.3.16 3.1.3.48]
120058246  dual specificity protein phosphatase 7-like [KO:K04459] [EC:3.1.3.16 3.1.3.48]
120052369  dual specificity protein phosphatase 8-like isoform X1 [KO:K04459] [EC:3.1.3.16 3.1.3.48]
120052735  si:ch211-195b15.8; tyrosine-protein phosphatase vhp-1 [KO:K04459] [EC:3.1.3.16 3.1.3.48]
120059494  dual specificity protein phosphatase 7-like [KO:K04459] [EC:3.1.3.16 3.1.3.48]
120066125  dusp8a; dual specificity protein phosphatase 8a isoform X1 [KO:K04459] [EC:3.1.3.16 3.1.3.48]
120061316  dual specificity protein phosphatase 7-like [KO:K04459] [EC:3.1.3.16 3.1.3.48]
120032056  anoctamin-6-like [KO:K19500]
120050003  anoctamin-6-like [KO:K19500]
120051663  ano3; LOW QUALITY PROTEIN: anoctamin-3 [KO:K19498]
120065987  anoctamin-3-like [KO:K19498]
120049391  anoctamin-4-like [KO:K19499]
120032168  anoctamin-4-like [KO:K19499]
120047841  anoctamin-5-like [KO:K19480]
120024904  anoctamin-5-like [KO:K19480]
120052321  ano5a; anoctamin-5 [KO:K19480]
120018694  ano7; anoctamin-7 [KO:K19501]
120058665  anoctamin-7-like [KO:K19501]
120061589  ano11; LOW QUALITY PROTEIN: anoctamin-7 [KO:K19501]
120024801  anoctamin-9-like [KO:K19503]
120056468  ano9b; anoctamin-9 [KO:K19503]
120051660  anoctamin-9-like [KO:K19503]
120053803  basigin-like [KO:K06535]
120054762  basigin-like [KO:K06535]
120022539  XK-related protein 8-like [KO:K26813]
120027255  XK-related protein 8-like [KO:K26813]
120022757  xkr8.3; XK-related protein 8.3 [KO:K26813]
120027927  xkr9; XK-related protein 9 [KO:K26814]
120039708  XK-related protein 9-like [KO:K26814]
120059237  XK-related protein 7-like [KO:K26811]
120060684  XK-related protein 7-like [KO:K26811]
120038938  XK-related protein 6-like [KO:K26811]
120020345  xkr4; XK-related protein 4 [KO:K26811]
120038219  XK-related protein 6 [KO:K26811]
120060017  XK-related protein 6-like [KO:K26811]
120055539  XK-related protein 4-like [KO:K26811]
120047984  probable phospholipid-transporting ATPase IA [KO:K14802] [EC:7.6.2.1]
120028162  atp8a2; phospholipid-transporting ATPase IB [KO:K14802] [EC:7.6.2.1]
120050605  phospholipid-transporting ATPase IB-like [KO:K14802] [EC:7.6.2.1]
120060147  probable phospholipid-transporting ATPase IA isoform X1 [KO:K14802] [EC:7.6.2.1]
120062324  phospholipid-transporting ATPase IG-like isoform X1 [KO:K26934] [EC:7.6.2.1]
120054878  probable phospholipid-transporting ATPase IF [KO:K26934] [EC:7.6.2.1]
120064302  probable phospholipid-transporting ATPase IH isoform X1 [KO:K26934] [EC:7.6.2.1]
120048141  phospholipid-transporting ATPase 11C-like isoform X1 [KO:K26934] [EC:7.6.2.1]
120052536  probable phospholipid-transporting ATPase IF [KO:K26934] [EC:7.6.2.1]
120050518  probable phospholipid-transporting ATPase IH [KO:K26934] [EC:7.6.2.1]
120033274  probable phospholipid-transporting ATPase IH [KO:K26934] [EC:7.6.2.1]
120058356  probable phospholipid-transporting ATPase IH [KO:K26934] [EC:7.6.2.1]
120060210  cell cycle control protein 50A-like isoform X1 [KO:K26935]
120024119  cell cycle control protein 50A-like [KO:K26935]
120023441  cell cycle control protein 50A-like isoform X1 [KO:K26935]
120038685  pros1; vitamin K-dependent protein S [KO:K03908]
120064520  integrin alpha-V-like [KO:K06487]
120034336  integrin beta-3-like [KO:K06493]
120035613  integrin beta-3-like [KO:K06493]
120046295  integrin beta-3-like [KO:K06493]
120064251  integrin beta-5-like [KO:K06588]
120058335  integrin beta-5-like [KO:K06588]
120039769  tyrosine-protein kinase receptor UFO-like [KO:K05115] [EC:2.7.10.1]
120057570  tyrosine-protein kinase receptor UFO [KO:K05115] [EC:2.7.10.1]
120023181  tyrosine-protein kinase receptor TYRO3-like isoform X1 [KO:K05116] [EC:2.7.10.1]
120060467  tyro3; tyrosine-protein kinase receptor TYRO3 [KO:K05116] [EC:2.7.10.1]
120030901  adhesion G protein-coupled receptor B1-like [KO:K04596]
120047204  adhesion G protein-coupled receptor B1-like [KO:K04596]
120037549  stab1; stabilin-1 [KO:K19020]
120050041  stab2; stabilin-2 [KO:K19013]
120022156  focal adhesion kinase 1-like [KO:K05725] [EC:2.7.10.2]
120048831  focal adhesion kinase 1-like isoform X1 [KO:K05725] [EC:2.7.10.2]
120048834  focal adhesion kinase 1-like [KO:K05725] [EC:2.7.10.2]
120027258  ptk2aa; protein tyrosine kinase 2aa isoform X1 [KO:K05725] [EC:2.7.10.2]
120053907  breast cancer anti-estrogen resistance protein 1-like isoform X1 [KO:K05726]
120066244  breast cancer anti-estrogen resistance protein 1-like isoform X1 [KO:K05726]
120018356  adapter molecule crk-like [KO:K04438]
120021245  crk-like protein [KO:K04438]
120025840  crk-like protein isoform X1 [KO:K04438]
120044371  adapter molecule crk-like [KO:K04438]
120028347  adapter molecule crk-like [KO:K04438]
120056896  adapter molecule crk-like [KO:K04438]
120022534  engulfment and cell motility protein 1-like [KO:K12366]
120027408  elmo1; engulfment and cell motility protein 1 [KO:K12366]
120030096  ras-related C3 botulinum toxin substrate 1 [KO:K04392]
120040646  ras-related C3 botulinum toxin substrate 1-like isoform X1 [KO:K04392]
120040650  ras-related C3 botulinum toxin substrate 1-like isoform X1 [KO:K04392]
120046821  ras-related C3 botulinum toxin substrate 1 [KO:K04392]
120044976  adam9; disintegrin and metalloproteinase domain-containing protein 9 isoform X1 [KO:K06834] [EC:3.4.24.-]
120038503  zgc:174164; disintegrin and metalloproteinase domain-containing protein 9 isoform X1 [KO:K06834] [EC:3.4.24.-]
120020436  calreticulin-like [KO:K08057]
120056138  calreticulin-like [KO:K08057]
120052517  calreticulin-like [KO:K08057]
120053761  calreticulin-like [KO:K08057]
120054719  calreticulin-like [KO:K08057]
120055519  calreticulin-like [KO:K08057]
120042226  c1qa; complement C1q subcomponent subunit A [KO:K03986]
120042227  c1qb; complement C1q subcomponent subunit B [KO:K03987]
120042225  c1qc; complement C1q subcomponent subunit C [KO:K03988]
120021297  low-density lipoprotein receptor-related protein 1-like [KO:K04550]
120059599  low-density lipoprotein receptor-related protein 1-like [KO:K04550]
120061032  low-density lipoprotein receptor-related protein 1-like [KO:K04550]
120025499  megf10; multiple epidermal growth factor-like domains protein 10 [KO:K24068]
120018233  scavenger receptor class F member 1-like isoform X1 [KO:K24318]
120028244  scavenger receptor class F member 1-like [KO:K24318]
120033697  gulp1b; PTB domain-containing engulfment adapter protein 1 [KO:K23285]
120063809  PTB domain-containing engulfment adapter protein 1-like [KO:K23285]
120058001  PTB domain-containing engulfment adapter protein 1-like [KO:K23285]
120060948  PTB domain-containing engulfment adapter protein 1-like isoform X1 [KO:K23285]
120064044  ras-related protein Rab-17-like [KO:K07909]
120022103  ras-related protein Rab-5A [KO:K07887]
120048378  ras-related protein Rab-5A-like [KO:K07887]
120031248  rab5ab; RAB5A, member RAS oncogene family, b [KO:K07887]
120026865  ras-related protein Rab-5A-like [KO:K07887]
120064233  ras-related protein Rab-5B-like [KO:K07888]
120058347  ras-related protein Rab-5B-like [KO:K07888]
120065254  ras-related protein Rab-5B-like [KO:K07888]
120034134  ras-related protein Rab-5C-like [KO:K07889]
120035891  ras-related protein Rab-5C-like [KO:K07889]
120046303  ras-related protein Rab-5C [KO:K07889]
120039476  transforming growth factor-beta receptor-associated protein 1 homolog [KO:K20177]
120041293  transforming growth factor-beta receptor-associated protein 1 homolog [KO:K20177]
120031398  vps11; vacuolar protein sorting-associated protein 11 homolog [KO:K20179]
120033384  vacuolar protein sorting-associated protein 16 homolog isoform X1 [KO:K20180]
120051465  vacuolar protein sorting-associated protein 16 homolog isoform X1 [KO:K20180]
120019194  vacuolar protein sorting-associated protein 18 homolog [KO:K20181]
120039370  vacuolar protein sorting-associated protein 18 homolog isoform X1 [KO:K20181]
120062979  vacuolar protein sorting-associated protein 33A [KO:K20182]
120054754  vacuolar protein sorting-associated protein 33A-like [KO:K20182]
120021212  ras-related protein Rab-14-like [KO:K07881]
120025693  ras-related protein Rab-14 [KO:K07881]
120044780  rab14; ras-related protein Rab-14 [KO:K07881]
120022970  vam6/Vps39-like protein [KO:K20183]
120036663  vps39; vam6/Vps39-like protein [KO:K20183]
120027818  vacuolar protein sorting-associated protein 41 homolog [KO:K20184]
120051142  vps41; vacuolar protein sorting-associated protein 41 homolog [KO:K20184]
120021230  ras-related protein Rab-7a-like [KO:K07897]
120025782  ras-related protein rab7-like [KO:K07897]
120063224  ras-related protein Rab-7a-like isoform X1 [KO:K07897]
120065088  ras-related protein rab7-like [KO:K07897]
120065205  ras-related protein rab7-like isoform X1 [KO:K07897]
120060502  ras-related protein rab7 [KO:K07897]
120061378  ras-related protein rab7-like [KO:K07897]
120018009  lysosomal amino acid transporter 1 homolog [KO:K23678]
120035938  lysosomal amino acid transporter 1 homolog [KO:K23678]
120059297  lysosomal amino acid transporter 1 homolog [KO:K23678]
120061238  lysosomal amino acid transporter 1 homolog [KO:K23678]
120023489  arginase-2, mitochondrial-like [KO:K01476] [EC:3.5.3.1]
120030041  arginase-1-like [KO:K01476] [EC:3.5.3.1]
120042450  arginase-2, mitochondrial-like [KO:K01476] [EC:3.5.3.1]
120046165  arginase-1-like [KO:K01476] [EC:3.5.3.1]
120023692  ornithine decarboxylase 1-like [KO:K01581] [EC:4.1.1.17]
120060379  ornithine decarboxylase 1-like [KO:K01581] [EC:4.1.1.17]
120017986  cholesterol 25-hydroxylase-like protein [KO:K10223] [EC:1.14.99.38]
120021879  cholesterol 25-hydroxylase-like protein 2 [KO:K10223] [EC:1.14.99.38]
120045437  ch25h; cholesterol 25-hydroxylase-like protein [KO:K10223] [EC:1.14.99.38]
120029730  cholesterol 25-hydroxylase-like protein [KO:K10223] [EC:1.14.99.38]
120029734  cholesterol 25-hydroxylase-like protein [KO:K10223] [EC:1.14.99.38]
120029768  cholesterol 25-hydroxylase-like protein [KO:K10223] [EC:1.14.99.38]
120029796  cholesterol 25-hydroxylase-like protein [KO:K10223] [EC:1.14.99.38]
120062780  cholesterol 25-hydroxylase-like protein [KO:K10223] [EC:1.14.99.38]
120053228  cholesterol 25-hydroxylase-like protein 1, member 1 [KO:K10223] [EC:1.14.99.38]
120065844  ch25hl1.2; LOW QUALITY PROTEIN: cholesterol 25-hydroxylase-like protein 1, member 2 [KO:K10223] [EC:1.14.99.38]
120066274  cholesterol 25-hydroxylase-like protein 1, member 1 [KO:K10223] [EC:1.14.99.38]
120024726  oxysterols receptor LXR-alpha-like isoform X1 [KO:K08536]
120045480  oxysterols receptor LXR-alpha-like isoform X1 [KO:K08536]
120039149  carnitine O-palmitoyltransferase 1, liver isoform-like isoform X1 [KO:K08765] [EC:2.3.1.21]
120024893  carnitine O-palmitoyltransferase 1, liver isoform-like isoform X1 [KO:K08765] [EC:2.3.1.21]
120033916  cpt1a2b; carnitine O-palmitoyltransferase 1, liver isoform isoform X1 [KO:K08765] [EC:2.3.1.21]
120046279  carnitine O-palmitoyltransferase 1, liver isoform-like [KO:K08765] [EC:2.3.1.21]
120066019  cpt1ab; carnitine O-palmitoyltransferase 1, liver isoform isoform X1 [KO:K08765] [EC:2.3.1.21]
120053968  carnitine O-palmitoyltransferase 1, liver isoform-like isoform X1 [KO:K08765] [EC:2.3.1.21]
120060659  carnitine O-palmitoyltransferase 1, liver isoform-like [KO:K08765] [EC:2.3.1.21]
120024906  cytochrome b-c1 complex subunit Rieske, mitochondrial [KO:K00411] [EC:7.1.1.8]
120046115  cytochrome b-c1 complex subunit Rieske, mitochondrial-like [KO:K00411] [EC:7.1.1.8]
120066423  cytochrome b-c1 complex subunit Rieske, mitochondrial-like [KO:K00411] [EC:7.1.1.8]
120017513  NAD-dependent protein deacetylase sirtuin-1-like [KO:K11411] [EC:2.3.1.286]
120046452  NAD-dependent protein deacetylase sirtuin-1-like isoform X1 [KO:K11411] [EC:2.3.1.286]
120020404  pre-B-cell leukemia transcription factor 1-like isoform X1 [KO:K09355]
120055906  pre-B-cell leukemia transcription factor 1-like [KO:K09355]
120052622  pbx1b; pre-B-cell leukemia transcription factor 1b [KO:K09355]
120054545  pre-B-cell leukemia transcription factor 1 isoform X1 [KO:K09355]
120037215  interleukin-10-like [KO:K05443]
120064680  il10; interleukin-10 [KO:K05443]
120046141  lipf; gastric triacylglycerol lipase [KO:K01052] [EC:3.1.1.13]
120029625  lysosomal acid lipase/cholesteryl ester hydrolase-like [KO:K01052] [EC:3.1.1.13]
120066182  phospholipase A2 group XV-like [KO:K06129] [EC:3.1.1.5]
120053829  phospholipase A2 group XV-like [KO:K06129] [EC:3.1.1.5]
120063287  peroxisome proliferator-activated receptor delta-like isoform X1 [KO:K04504]
120065343  peroxisome proliferator-activated receptor delta-like isoform X1 [KO:K04504]
120060987  ppardb; peroxisome proliferator-activated receptor delta b [KO:K04504]
120042446  solute carrier family 2, facilitated glucose transporter member 1 [KO:K07299]
120058962  solute carrier family 2, facilitated glucose transporter member 1-like [KO:K07299]
120065116  solute carrier family 2, facilitated glucose transporter member 1-like [KO:K07299]
120059686  solute carrier family 2, facilitated glucose transporter member 1-like [KO:K07299]
120060729  solute carrier family 2, facilitated glucose transporter member 1-like [KO:K07299]
120058590  monocarboxylate transporter 1-like [KO:K08179]
120065028  monocarboxylate transporter 1-like [KO:K08179]
120061536  monocarboxylate transporter 1-like [KO:K08179]
120022563  serine/threonine-protein kinase Sgk1-like [KO:K13302] [EC:2.7.11.1]
120030978  serine/threonine-protein kinase Sgk1-like [KO:K13302] [EC:2.7.11.1]
120048857  serine/threonine-protein kinase Sgk1-like [KO:K13302] [EC:2.7.11.1]
120027205  serine/threonine-protein kinase Sgk1-like [KO:K13302] [EC:2.7.11.1]
120039472  platelet endothelial cell adhesion molecule-like isoform X1 [KO:K06471]
120032891  si:dkey-237i9.8; platelet endothelial cell adhesion molecule isoform X1 [KO:K06471]
120034412  platelet endothelial cell adhesion molecule-like isoform X1 [KO:K06471]
120048592  tyrosine-protein phosphatase non-receptor type 6-like isoform X1 [KO:K05697] [EC:3.1.3.48]
120048714  tyrosine-protein phosphatase non-receptor type 6-like isoform X1 [KO:K05697] [EC:3.1.3.48]
120025952  tyrosine-protein phosphatase non-receptor type 11-like [KO:K07293] [EC:3.1.3.48]
120044964  ptpn11a; tyrosine-protein phosphatase non-receptor type 11 isoform X1 [KO:K07293] [EC:3.1.3.48]
120059394  tyrosine-protein phosphatase non-receptor type 11-like isoform X1 [KO:K07293] [EC:3.1.3.48]
120060938  tyrosine-protein phosphatase non-receptor type 11-like isoform X1 [KO:K07293] [EC:3.1.3.48]
Compound
C00002  ATP
C00003  NAD+
C00019  S-Adenosyl-L-methionine
C00031  D-Glucose
C00062  L-Arginine
C00073  L-Methionine
C00075  UTP
C00077  L-Ornithine
C00134  Putrescine
C00162  Fatty acid
C00186  (S)-Lactate
C00187  Cholesterol
C00584  Prostaglandin E2
C02530  Cholesterol ester
C02737  Phosphatidylserine
C04230  1-Acyl-sn-glycero-3-phosphocholine
C06124  Sphingosine 1-phosphate
C06314  Lipoxin A4
C15519  25-Hydroxycholesterol
C15610  Cholest-5-ene-3beta,26-diol
C18178  Resolvin D1
Reference
PMID:31822793
  Authors
Doran AC, Yurdagul A Jr, Tabas I
  Title
Efferocytosis in health and disease.
  Journal
Nat Rev Immunol 20:254-267 (2020)
DOI:10.1038/s41577-019-0240-6
Reference
PMID:36028471
  Authors
Zhang J, Ding W, Zhao M, Liu J, Xu Y, Wan J, Wang M
  Title
Mechanisms of efferocytosis in determining inflammation resolution: Therapeutic potential and the association with cardiovascular disease.
  Journal
Br J Pharmacol 179:5151-5171 (2022)
DOI:10.1111/bph.15939
Reference
PMID:30165442
  Authors
Kawano M, Nagata S
  Title
Efferocytosis and autoimmune disease.
  Journal
Int Immunol 30:551-558 (2018)
DOI:10.1093/intimm/dxy055
Reference
PMID:35650427
  Authors
Mehrotra P, Ravichandran KS
  Title
Drugging the efferocytosis process: concepts and opportunities.
  Journal
Nat Rev Drug Discov 21:601-620 (2022)
DOI:10.1038/s41573-022-00470-y
Reference
PMID:28496201
  Authors
Park SY, Kim IS
  Title
Engulfment signals and the phagocytic machinery for apoptotic cell clearance.
  Journal
Exp Mol Med 49:e331 (2017)
DOI:10.1038/emm.2017.52
Reference
PMID:28137963
  Authors
Kojima Y, Weissman IL, Leeper NJ
  Title
The Role of Efferocytosis in Atherosclerosis.
  Journal
Circulation 135:476-489 (2017)
DOI:10.1161/CIRCULATIONAHA.116.025684
Related
pathway
snh00010  Glycolysis / Gluconeogenesis
snh04140  Autophagy - animal
snh04145  Phagosome
KO pathway
ko04148   
LinkDB

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