KEGG ORTHOLOGY: K13141

ORTHOLOGY: K13141

Entry

K13141                      KO

Symbol

INTS4

Name

integrator complex subunit 4

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03041 Spliceosome
    K13141  INTS4; integrator complex subunit 4
Spliceosome [BR:ko03041]
Other splicing related proteins
  Proteins involved in snRNP biogenesis
   Integrator complex
    K13141  INTS4; integrator complex subunit 4

Genes

HSA:	92105(INTS4)

PTR:	451444(INTS4) 451720

PPS:	100980688(INTS4)

GGO:	101140161 101147285(INTS4) 109027741

PON:	100454725(INTS4)

NLE:	100586089(INTS4)

HMH:	116476731(INTS4)

MCC:	699466(INTS4)

MCF:	102115656(INTS4)

MTHB:

126935683

MNI:	105468804(INTS4)

CSAB:

103248097(INTS4)

CATY:

105578696(INTS4)

PANU:

101021448(INTS4)

TGE:	112606769(INTS4)

MLEU:

105546506(INTS4)

RRO:	104664310(INTS4)

RBB:	108543191(INTS4)

TFN:	117080691(INTS4)

PTEH:

111540801(INTS4)

CANG:

105509643(INTS4)

CJC:	100413473(INTS4)

SBQ:	101049925(INTS4)

CIMI:

108296251(INTS4)

CSYR:

103270090(INTS4)

MMUR:

105860334

LCAT:

123642296(INTS4)

PCOQ:

105815754(INTS4)

OGA:	100943695(INTS4)

MMU:	101861(Ints4)

MCAL:

110298396(Ints4)

MPAH:

110319674(Ints4)

RNO:	308837(Ints4)

MCOC:

116102592(Ints4)

ANU:	117718710(Ints4)

MUN:	110547311(Ints4)

CGE:	100767027(Ints4)

MAUA:

101842795(Ints4)

PROB:

127227919(Ints4)

PLEU:

114698670(Ints4)

MORG:

121446933 121458899

MFOT:

126508946

AAMP:

119802684(Ints4)

NGI:	103743000(Ints4)

HGL:	101713022 101725797(Ints4)

CPOC:

100712822(Ints4)

CCAN:

109683798(Ints4)

DORD:

105984089(Ints4)

DSP:	122115379(Ints4)

PLOP:

125361288(Ints4)

NCAR:

124958879

MMMA:

107135478(Ints4)

OCU:

100350308

OPI:	101525921(INTS4)

TUP:	102487505(INTS4)

GVR:	103585113(INTS4)

CFA:	100684631 100685836 100685895 476795(INTS4)

CLUD:

112642126(INTS4) 112670475 125752060

VVP:	112928725(INTS4)

VLG:	121476409(INTS4) 121484148

NPO:	129506645(INTS4)

AML:	100466397(INTS4)

UMR:	103678075(INTS4)

UAH:	113269360(INTS4)

UAR:	123804172(INTS4)

ELK:

111154473

LLV:

125080072

MPUF:

101670742

MNP:	132024723(INTS4)

MLK:	131840310(INTS4)

NVS:	122912550(INTS4)

ORO:	101367877(INTS4)

EJU:	114218698(INTS4)

ZCA:	113914605(INTS4)

MLX:	118004202(INTS4)

NSU:	110593342(INTS4)

LWW:	102725821(INTS4)

FCA:	101080997(INTS4)

PYU:	121039336(INTS4)

PCOO:

112865317(INTS4)

PBG:	122483295(INTS4)

PVIV:

125177133(INTS4)

LRUF:

124505350

PTG:	102972827(INTS4)

PPAD:

109267260(INTS4)

PUC:

125914465

AJU:

106980804

HHV:	120229606(INTS4)

BTA:	505657(INTS4)

BOM:	102277163(INTS4)

BIU:	109554294(INTS4)

BBUB:

102407016(INTS4)

BBIS:

104998169(INTS4)

CHX:	102178981(INTS4)

OAS:	101110460(INTS4)

BTAX:

128068643(INTS4)

ODA:	120874279(INTS4)

CCAD:

122431354(INTS4)

MBEZ:

129549031(INTS4)

SSC:	100512005(INTS4)

CFR:	102516740(INTS4)

CBAI:

105083561(INTS4)

CDK:	105097502(INTS4)

VPC:	102544979(INTS4)

BACU:

103013195(INTS4)

BMUS:

118898907(INTS4)

LVE:	103081228(INTS4)

OOR:	101289669(INTS4)

DLE:	111184905(INTS4)

PCAD:

102981845(INTS4)

PSIU:

116757617(INTS4)

NASI:

112402462(INTS4)

ECB:	100051369(INTS4)

EPZ:	103553806(INTS4)

EAI:	106842892(INTS4)

MYB:	102253885(INTS4)

MYD:	102757356(INTS4)

MMYO:

118664596(INTS4)

MLF:	102426607(INTS4)

PKL:	118713675(INTS4)

EFUS:

103293692(INTS4)

MNA:	107524436(INTS4)

DRO:	112315856(INTS4)

AJM:	119044294(INTS4)

PDIC:

114499299(INTS4)

PHAS:

123805652(INTS4)

MMF:	118627826(INTS4)

PPAM:

129072778(INTS4)

HAI:

109376008

RFQ:	117030445(INTS4)

PALE:

102881528(INTS4)

PGIG:

120590391(INTS4)

PVP:	105297607(INTS4)

RAY:	107519161(INTS4)

MJV:	108401309(INTS4)

TOD:	119255661(INTS4)

SARA:

101538316(INTS4)

SETR:

126013236(INTS4)

LAV:	100661189(INTS4)

TMU:

101344802

ETF:	101653169(INTS4)

DNM:

101439619

MDO:	100018147(INTS4)

GAS:	123240523(INTS4)

SHR:	100928540(INTS4)

AFZ:

127555119

PCW:	110210529(INTS4)

OAA:	114805831(INTS4)

GGA:	419028(INTS4)

PCOC:

116233884(INTS4)

MGP:	100541547(INTS4)

CJO:	107308543(INTS4)

TPAI:

128074016(INTS4)

LMUT:

125687949(INTS4)

NMEL:

110391264(INTS4)

APLA:

101800262(INTS4)

ACYG:

106039861(INTS4)

CATA:

118254801(INTS4)

AFUL:

116501862(INTS4)

TGU:	100222075(INTS4)

LSR:	110472345(INTS4)

SCAN:

103827223(INTS4)

PMOA:

120498416(INTS4)

OTC:	121341017(INTS4)

PRUF:

121350529(INTS4)

GFR:	102038130(INTS4)

FAB:	101821572(INTS4)

OMA:	130255617(INTS4)

PHI:	102108175(INTS4)

PMAJ:

107200198(INTS4)

CCAE:

111925503(INTS4)

CCW:	104690341(INTS4)

CBRC:

103616736(INTS4)

ETL:	114065461(INTS4)

ZAB:	102063976(INTS4)

ACHL:

103798199(INTS4)

SVG:	106859839(INTS4)

MMEA:

130580302(INTS4)

HRT:	120748582(INTS4)

FPG:	101923803(INTS4)

FCH:	102054516(INTS4)

CLV:	102098696(INTS4)

EGZ:	104124739(INTS4)

NNI:	104022775(INTS4)

PCRI:

104037509(INTS4)

PLET:

104617768(INTS4)

PCAO:

104042749(INTS4)

ACUN:

113488337(INTS4)

TALA:

104361081(INTS4)

PADL:

103915181(INTS4)

AFOR:

103904658(INTS4)

ACHC:

115353444(INTS4)

HALD:

104317375(INTS4)

HLE:	104837454(INTS4)

AGEN:

126048497

GCL:

127017258

CCRI:

104158720(INTS4)

CSTI:

104561249(INTS4)

MUI:	104542118(INTS4)

BREG:

104634930(INTS4)

FGA:	104075135(INTS4)

GSTE:

104250266(INTS4)

LDI:	104340188(INTS4)

MNB:	103769837(INTS4)

OHA:	104326281(INTS4)

SHAB:

115604521(INTS4)

DPUB:

104299863(INTS4)

PGUU:

104468596(INTS4)

ACAR:

104529701(INTS4)

CPEA:

104391733(INTS4)

AVIT:

104272884(INTS4)

CVF:	104283106(INTS4)

RTD:	128906242(INTS4)

CUCA:

104064140(INTS4)

TEO:	104378992(INTS4)

BRHI:

104492395(INTS4)

AAM:	106485971(INTS4)

AROW:

112972077(INTS4)

NPD:	112943390(INTS4)

TGT:	104572706(INTS4)

DNE:	112981922(INTS4)

SCAM:

104152796(INTS4)

ASN:	102370445(INTS4)

AMJ:	102569954(INTS4)

CPOO:

109306829(INTS4)

GGN:	109302872(INTS4)

PSS:	102455657(INTS4)

CMY:	102938782(INTS4)

CCAY:

125632408(INTS4)

DCC:	119855607(INTS4)

CPIC:

101938266(INTS4)

TST:	117871273(INTS4)

CABI:

116819278(INTS4)

MRV:	120378903(INTS4)

ACS:	100565451(ints4)

ASAO:

132772278(INTS4)

PVT:	110088566(INTS4)

SUND:

121926733(INTS4)

PBI:

103057719

PMUR:

107297918(INTS4) 107300446

CTIG:

120320394(INTS4)

TSR:	106553097(INTS4)

PGUT:

117660223(INTS4)

APRI:

131200133(INTS4)

PTEX:

113440411(INTS4)

NSS:	113426984(INTS4)

VKO:	123033525(INTS4)

PMUA:

114595569(INTS4)

PRAF:

128412258(INTS4)

ZVI:	118085140(INTS4)

HCG:	128351352(INTS4)

GJA:	107118389(INTS4)

STOW:

125432024

EMC:	129326460(INTS4)

XLA:	447293(ints4.L)

XTR:	100498633(ints4)

NPR:	108797995(INTS4)

RTEM:

120928884(INTS4)

BBUF:

120996486(INTS4)

BGAR:

122931881(INTS4)

MUO:	115468405(INTS4)

GSH:	117362070(INTS4)

DRE:	564681(ints4)

SRX:	107735140(ints4)

SANH:

107660682(ints4)

SGH:	107594370 107600803

CCAR:

109047609 109063308

CAUA:

113118108(ints4)

CGIB:

127977299

PTET:

122362930(ints4)

LROH:

127180683(ints4)

OMC:	131524167(ints4)

PPRM:

120473748(ints4)

RKG:	130100432(ints4)

MAMB:

125254067(ints4)

CIDE:

127499913

MASI:

127456028

TROS:

130562387(ints4)

TDW:	130435440(ints4)

MANU:

129419648(ints4)

IPU:

108264463

IFU:	128606913(ints4)

PHYP:

113526725(ints4)

SMEO:

124395494(ints4)

TFD:	113642391(ints4)

TVC:	132851020(ints4)

AMEX:

103037017(ints4)

CMAO:

118818057(ints4)

EEE:	113576966(ints4)

CHAR:

105907826(ints4)

TRU:	101077263(ints4)

TFS:	130535100(ints4)

TNG:	GSTEN00011427G001

NCC:	104956947(ints4)

TBEN:

117484310(ints4)

CGOB:

115018186(ints4)

PGEO:

117457777(ints4)

GACU:

117560678(ints4)

EMAC:

134880080(ints4)

ELY:	117259585(ints4)

EFO:	125889124(ints4)

PLEP:

121942918(ints4)

SLUC:

116053142(ints4)

ECRA:

117941749(ints4)

ESP:	116685753(ints4)

PFLV:

114552416(ints4)

GAT:	120821317(ints4)

PPUG:

119217730(ints4)

AFB:	129092669(ints4)

CLUM:

117728108(ints4)

PSWI:

130210933(ints4)

MSAM:

119883148(ints4)

SCHU:

122878871(ints4)

CUD:	121525541(ints4)

ALAT:

119006763(ints4)

MZE:	101468969(ints4)

ONL:	100696896(ints4)

OAU:	116321817(ints4)

OLA:	101166892(ints4)

OML:	112149711(ints4)

CSAI:

133442025(ints4)

XMA:	102236944(ints4)

XCO:	114161334(ints4)

XHE:	116737640(ints4)

PRET:

103475099(ints4)

PFOR:

103138245(ints4)

PLAI:

106963170(ints4)

PMEI:

106917692(ints4)

GAF:	122833144(ints4)

PPRL:

129359137(ints4)

CVG:	107091633(ints4)

CTUL:

119785727(ints4)

GMU:	124883898(ints4)

NFU:	107379838(ints4)

KMR:	108244689(ints4)

ALIM:

106535533(ints4)

NWH:	119410800(ints4)

AOCE:

111568843(ints4)

MCEP:

125013856(ints4)

CSEM:

103378299(ints4)

POV:	109644218(ints4)

SSEN:

122773318(ints4)

HHIP:

117772945(ints4)

HSP:	118105845(ints4)

SMAU:

118299083(ints4)

LCF:

108882377

SDU:	111216902(ints4)

SLAL:

111647543(ints4)

XGL:	120791895(ints4)

HCQ:	109514416(ints4)

SSCV:

125972343

SBIA:

133504567(ints4)

PEE:	133405196(ints4)

PTAO:

133482156(ints4)

BPEC:

110161093(ints4)

BSPL:

114867816(ints4)

SJO:	128360914(ints4)

SASA:

100380424(ints4)

STRU:

115206223(ints4)

OTW:	112265427 112266984(ints4)

OMY:	110503802(ints4) 110507104

OGO:	124004838(ints4)

ONE:	115118317(ints4) 115136853

OKI:	109909081(ints4)

OKE:	118373012(ints4)

SALP:

111959627(ints4)

SNH:	120028298(ints4)

CCLU:

121567864(ints4)

ELS:	105010852(ints4)

SFM:	108924641(ints4)

PKI:	111833851(ints4)

AANG:

118210262(ints4)

LOC:	102691788(ints4)

PSPA:

121302714(ints4)

ARUT:

117405976 117962958 117972775

PSEX:

120523185(ints4)

LCM:

102362465

CMK:	103191576(ints4) 121851696

RTP:	109917069(ints4)

CPLA:

122550956(ints4)

HOC:	132816567(ints4)

LERI:

129715969(ints4)

PMRN:

116952564(INTS4)

LRJ:	133353795(INTS4)

BFO:

BBEL:

CIN:

SCLV:

SPU:	115922628 582137

LPIC:

129278783 129279342

APLC:

110983236

AJC:

117118912

DME:	Dmel_CG12113(IntS4)

DER:

6549687

DSE:

6619826

DSI:	Dsimw501_GD19026(Dsim_GD19026)

DYA:	Dyak_GE17446

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI14774

DAZ:

DNV:

DHE:

DVI:

CCAT:

BOD:

BDR:

RZE:

AOQ:

TDA:

MDE:

SCAC:

LCQ:

LSQ:

GFS:	119643986 119643988 119644056

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AMOU:

AALI:

AAG:

AALB:

CQU:	CpipJ_CPIJ015422

CPII:

CNS:

BCOO:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

TCA:

DPA:

SOY:

AGRG:

ATD:

CSET:

AGB:	108907725 108913122

LDC:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

PGW:

CFEL:

CCRN:

API:

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

DCI:

CLEC:

HHAL:

NLU:	111046853 111056068 120355968

HVI:

124354994

MQU:	128996741 128997106

PHU:	Phum_PHUM489300

FOC:

TPAL:

ZNE:

CSEC:

SGRE:

BROR:

IEL:

FCD:

DPX:	DAPPUDRAFT_328539

DMK:

DPZ:

PVM:

PJA:

PCHN:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

MNZ:

HAZT:

EAF:

LSM:

TCF:

PPOI:

ISC:

DSV:

RMP:

VDE:

VJA:

TUT:

DPTE:

DFR:

CSCU:

PTEP:

ABRU:

UDV:	129233995 129234126

SDM:

118201656

PMEO:

129602790

CEL:	CELE_W04A4.5(ints-4)

CBR:

CBG_19769

CRQ:	GCK72_003598

NAI:	NECAME_13902

LOA:	LOAG_16804

TSP:	Tsp_04102 Tsp_13296

HRO:	HELRODRAFT_101627

LGI:	LOTGIDRAFT_220695

PVUL:

PCAN:

BGT:

GAE:

HRF:

HRJ:

CRG:

CVN:

CANU:

OED:

MYI:

PMAX:

MCAF:

MMER:

RPHI:

DPOL:

OBI:

OSN:

LAK:

SMM:	Smp_123130

SHX:	MS3_00008792(INTS4)

OVI:	T265_02621

EGL:

NVE:

EPA:

ATEN:

ADF:

AMIL:

PDAM:

SPIS:

DGT:

XEN:

HMG:

HSY:

TAD:	TRIADDRAFT_19885

AQU:	100633912 100634162 100639368

ATH:	AT3G08800(SIEL)

ALY:

9318651

CRB:

17893237

CSAT:

104745035 104745793 104764571 109129055

EUS:	EUTSA_v10022535mg

BRP:

103870585

BNA:	106401659 106452831

BOE:

RSZ:

THJ:

CPAP:

CIT:

CIC:	CICLE_v10024812mg

PVY:	116143421 116143423

MINC:

123218766

TCC:

18597449

GRA:

105780359

GHI:	107899593 107948957

GAB:

HSYR:

DZI:

EGR:

GMX:

GSJ:

PVU:	PHAVU_008G092100g

VRA:	106754919 106777659

VAR:	108318877 108334776

VUN:

114183366

VUM:	124822488 124829924

CCAJ:

APRC:

MTR:

TPRA:

CAM:

PSAT:

VVO:

LJA:	Lj1g3v2379130.1(Lj1g3v2379130.1) Lj1g3v2379130.2(Lj1g3v2379130.2) Lj1g3v2379130.3(Lj1g3v2379130.3)

ADU:

107485062

AIP:

107636898

AHF:	112743737 112797108

LANG:

109325192

PCIN:

129315498

QSA:	O6P43_026294

FVE:

RCN:

PPER:

PMUM:

PAVI:

PDUL:

MDM:

MSYL:

PXB:

ZJU:

MNT:

CSAV:

CSV:

CMO:

BHJ:

MCHA:

CMAX:

CMOS:

CPEP:

RCU:

JCU:

HBR:

MESC:

POP:

PEU:	105118762 105131369 105131371

PALZ:

JRE:

CILL:

CAVE:

QSU:

QLO:

TWL:

VVI:

VRI:

SLY:

SPEN:

SOT:

SSTN:

SDUL:

CANN:

LBB:

NTA:	107769626 107805433

NSY:

NTO:

NAU:

INI:

ITR:

SIND:

OEU:

EGT:

SSPL:

SMIL:

APAN:

HAN:

ECAD:

LSV:

CCAV:

DCR:

CSIN:

RVL:

AEW:

BVG:

SOE:

CQI:	110733871 110735428

ATRI:

MOF:

NNU:

MING:

TSS:

PSOM:

113283858 113290953 113329217

OSA:

OBR:

OGL:

BDI:

ATS:

TDC:	119285324 119290765 119317378

TAES:

123085499 123092532 123097848

TUA:	125513930 125514036 125552089

LPER:

127295916

LRD:	124702133 124702292

SBI:

ZMA:

SITA:

SVS:

PVIR:

PHAI:

PDA:

EGU:

MUS:

DCT:

PEQ:

AOF:

MSIN:

NCOL:

ATR:

SMO:	SELMODRAFT_412179 SELMODRAFT_439432

PPP:

112283779

EIN:	Eint_090860

EHE:	EHEL_090870

ERO:	EROM_091300

MBR:	MONBRDRAFT_36177

SRE:	PTSG_01198

DDI:	DDB_G0286633(ints4)

DPP:	DICPUDRAFT_151099

DFA:	DFA_05412(ints4)

ACAN:

ACA1_180820

TET:	TTHERM_00467840

PTM:	GSPATT00007136001

GTT:	GUITHDRAFT_119665

NGR:	NAEGRDRAFT_79682

» show all

Reference

PMID:22250197

Authors

Takata H, Nishijima H, Maeshima K, Shibahara K

Title

The integrator complex is required for integrity of Cajal bodies.

Journal

J Cell Sci 125:166-75 (2012)
DOI:10.1242/jcs.090837

Sequence

[hsa:92105]

LinkDB

DBGET integrated database retrieval system