KEGG ORTHOLOGY: K19559

ORTHOLOGY: K19559

Entry

K19559                      KO

Symbol

LTBP1

Name

latent transforming growth factor beta binding protein 1

Pathway

map04350

TGF-beta signaling pathway

Disease

H00557

Cutis laxa

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04350 TGF-beta signaling pathway
    K19559  LTBP1; latent transforming growth factor beta binding protein 1
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04990 Domain-containing proteins not elsewhere classified
    K19559  LTBP1; latent transforming growth factor beta binding protein 1
Domain-containing proteins not elsewhere classified [BR:ko04990]
EGF-like domain-containing proteins
  hEGF / cEGF domain-containing proteins
   K19559  LTBP1; latent transforming growth factor beta binding protein 1

Other DBs

GO:

0050431

Genes

HSA:	4052(LTBP1)

PTR:	459143(LTBP1)

PPS:	100974244(LTBP1)

GGO:	101144521(LTBP1)

PON:	100447512(LTBP1)

PPYG:

129030276(LTBP1)

NLE:	100602834(LTBP1)

HMH:	116480554(LTBP1)

SSYN:

129467808(LTBP1)

MCC:	709607(LTBP1)

MCF:	102136496(LTBP1)

MTHB:

126933889

MNI:	105464817(LTBP1)

CSAB:

103220522(LTBP1)

CATY:

105578393(LTBP1)

PANU:

101001119(LTBP1)

TGE:	112604778(LTBP1)

MLEU:

105542615(LTBP1)

RRO:	104669442(LTBP1)

RBB:	108528681(LTBP1)

TFN:	117062492(LTBP1)

PTEH:

111545407(LTBP1)

CANG:

105507493(LTBP1)

CJC:	100404471(LTBP1)

SBQ:	101043946(LTBP1)

CIMI:

108308848(LTBP1)

ANAN:

105733091(LTBP1)

CSYR:

103253340(LTBP1)

MMUR:

105884479(LTBP1)

LCAT:

123636784(LTBP1)

ERUF:

138400191(LTBP1)

PCOQ:

105816883(LTBP1)

OGA:	100955779(LTBP1)

MMU:	268977(Ltbp1)

MCAL:

110312411(Ltbp1)

MPAH:

110335890(Ltbp1)

RNO:	59107(Ltbp1)

MCOC:

116081184(Ltbp1)

ANU:	117716894(Ltbp1)

ASYL:

127687585(Ltbp1)

MUN:	110562662(Ltbp1)

CGE:	100764759(Ltbp1)

MAUA:

101833414(Ltbp1)

PROB:

127220135(Ltbp1)

PLEU:

114695932(Ltbp1)

PMAV:

102918294(Ltbp1)

MORG:

121432873(Ltbp1)

MFOT:

126514221

AAMP:

119807084(Ltbp1)

CNL:	130877730(Ltbp1)

NGI:	103746758(Ltbp1)

HGL:	101715513(Ltbp1)

CPOC:

100733334(Ltbp1)

CCAN:

109694260(Ltbp1)

DORD:

105983691(Ltbp1)

DSP:	122122436(Ltbp1)

DMER:

138829187(Ltbp1)

PLOP:

125356573(Ltbp1)

NCAR:

124962971

MMMA:

107137364(Ltbp1)

ITI:	101974364(Ltbp1)

OCU:

100342431

OPI:	101527793(LTBP1)

OCZ:	121164798(LTBP1)

TUP:	102500312(LTBP1)

GVR:	103597237(LTBP1)

CFA:	475720(LTBP1)

CLUD:

112664550(LTBP1)

VVP:	112932982(LTBP1)

VLG:	121491258(LTBP1)

NPO:	129510940(LTBP1)

AML:	100484873(LTBP1)

UMR:	103671591(LTBP1)

UAH:	113241141(LTBP1)

UAR:	123799846(LTBP1)

ELK:

111158428

LLV:

125109052

MPUF:

101692389(LTBP1)

MNP:	132021286(LTBP1)

MLK:	131840529(LTBP1)

NVS:	122915156(LTBP1)

ORO:	101372092(LTBP1)

EJU:	114219673(LTBP1)

ZCA:	113937314(LTBP1)

MLX:	118007514(LTBP1)

MANO:

123850969(LTBP1)

NSU:	110587425(LTBP1)

LWW:

102733506

FCA:	101084534(LTBP1)

PYU:	121044328(LTBP1)

PCOO:

112864118(LTBP1)

PBG:	122466912(LTBP1)

PVIV:

125162076(LTBP1)

LRUF:

124503695

LGF:	123581258(LTBP1)

AJU:

106967893

PTG:	102955897(LTBP1)

PPAD:

109266042(LTBP1)

PUC:

125937545

PLEZ:

122216437(LTBP1)

HHV:	120244024(LTBP1)

CCRU:

144238863(LTBP1)

BTA:	510559(LTBP1)

BOM:	102267403(LTBP1)

BIU:

109565966

BJV:	133256871(LTBP1)

BBUB:

102410007(LTBP1)

BKE:	129622904(LTBP1)

BBIS:

104980949(LTBP1)

CHX:	102190794(LTBP1)

OAS:	101102219(LTBP1)

OCAN:

138437054(LTBP1)

BTAX:

128056054(LTBP1)

CSUM:

138092458(LTBP1)

ODA:	120851658(LTBP1)

CCAD:

122441551(LTBP1)

MREE:

136164473(LTBP1)

OVR:	110129460(LTBP1)

MBEZ:

129539880(LTBP1)

SSC:	100627243(LTBP1)

CFR:	102504170(LTBP1)

CBAI:

105078953(LTBP1)

CDK:	105095516(LTBP1)

VPC:	102538375(LTBP1)

BACU:

103009669(LTBP1)

BMUS:

118905915(LTBP1)

LVE:	103071173(LTBP1)

OOR:	101288387(LTBP1)

LALB:

132531973(LTBP1)

GMF:	115854136(LTBP1)

DDP:	132434996(LTBP1)

DLE:	111174895(LTBP1)

PCAD:

102973572

PSIU:

116764399(LTBP1)

PPHC:

136134235(LTBP1)

NASI:

112391064(LTBP1)

ECB:	100070522(LTBP1)

EPZ:	103565382(LTBP1)

EAI:	106839889(LTBP1)

MYB:	102259496(LTBP1)

MYD:	102771353(LTBP1)

MMYO:

118669113(LTBP1)

MLF:

102419310

MDT:	132213483(LTBP1)

MYUM:

139019810(LTBP1)

PKL:	118717123(LTBP1)

EFUS:

103305478(LTBP1)

MNA:	107541772(LTBP1)

DRO:	112297823(LTBP1)

SHON:

119001281(LTBP1)

AJM:	119050337(LTBP1)

PDIC:

114499363(LTBP1)

PHAS:

123811141(LTBP1)

MMF:	118630517(LTBP1)

PPAM:

129066404(LTBP1)

HAI:	109388785(LTBP1)

RFQ:	117032961(LTBP1)

PALE:

102888075(LTBP1)

PGIG:

120621791(LTBP1)

PVP:	105300066(LTBP1)

RAY:	107505737(LTBP1)

MJV:	108409270(LTBP1)

TOD:	119259414(LTBP1)

SARA:

101553015(LTBP1)

SFUM:

130033465(LTBP1)

SETR:

126023800(LTBP1)

LAV:	100675217(LTBP1)

TMU:

101345588

ETF:	101663849(LTBP1)

DNM:

101432493

MDO:	100031586(LTBP1)

GAS:	123237051(LTBP1)

SHR:	100915554(LTBP1)

AFZ:

127548643

PCW:	110198163(LTBP1)

TVP:	118841731(LTBP1)

PBRV:

138149184(LTBP1)

MLAO:

141504589(LTBP1)

OAA:	100080090(LTBP1)

TACU:

119940137(LTBP1)

GGA:	421461(LTBP1)

PCOC:

116229123(LTBP1)

MGP:

100542113

CJO:	107311288(LTBP1)

TPAI:

128081093(LTBP1)

LMUT:

125689861(LTBP1)

NMEL:

110395668(LTBP1)

APLA:

101791663(LTBP1)

AACU:

137853744(LTBP1)

OJA:	118163622(LTBP1)

ACYG:

106029586(LTBP1)

CATA:

118253146(LTBP1)

AFUL:

116487802(LTBP1)

TGU:	100232161(LTBP1)

LSR:	110477905(LTBP1)

VMC:	128805260(LTBP1)

VCHA:

128785856(LTBP1)

AIB:	137471181(LTBP1)

SCAN:

103817502(LTBP1)

PMOA:

120506900(LTBP1)

OTC:	121335822(LTBP1)

PRUF:

121358778(LTBP1)

ATRC:

139591351(LTBP1)

MATE:

118685495(LTBP1)

MAEN:

136554587(LTBP1)

GFR:	102040757(LTBP1)

FAB:	101809660(LTBP1)

OMA:	130251469(LTBP1)

PHI:

102113133

PMAJ:

107201849(LTBP1)

CCAE:

111926965(LTBP1)

CCW:	104684364(LTBP1)

CBRC:

103624134(LTBP1)

ACOE:

138108016(LTBP1)

ETL:	114065391(LTBP1)

ZAB:	102063724(LTBP1)

ZLE:	135445747(LTBP1)

ACHL:

103803217(LTBP1)

SVG:	106853187(LTBP1)

MMEA:

130575806(LTBP1)

HRT:	120750145(LTBP1)

SATI:

136359339(LTBP1)

CFAI:

136286720(LTBP1)

CCIC:

134042620(LTBP1)

FPG:	101911700(LTBP1)

FCH:	102049121(LTBP1)

FRS:	119156131(LTBP1)

NNT:	104401990(LTBP1)

SHAB:

115613684(LTBP1)

POCC:

134169215(LTBP1)

ACUN:

113478366(LTBP1)

ANOC:

141956380(LTBP1)

SURA:

141941142(LTBP1)

TALA:

104360032(LTBP1)

ACHC:

115350179(LTBP1)

HLE:	104840335(LTBP1)

AGEN:

126051544

HHAR:

128150140(LTBP1)

BBUT:

142038090(LTBP1)

GCL:

127015309

CSTI:

104561276(LTBP1)

LDI:	104353768(LTBP1)

MNB:	103781199(LTBP1)

DPUB:

104302231

PPUS:

135183583(LTBP1)

IIN:	128979862(LTBP1)

AVIT:

104279216(LTBP1)

BRHI:

104502145(LTBP1)

EGZ:	104124128(LTBP1)

NNI:	104018675(LTBP1)

PARX:

142055369(LTBP1)

PADL:

103922847(LTBP1)

AFOR:

103902688(LTBP1)

FGA:	104083326(LTBP1)

CBOR:

142080749(LTBP1)

GSTE:

104262836

CBOY:

140649425(LTBP1)

MAME:

142407070(LTBP1)

CLV:	102090468(LTBP1)

CNIC:

135986505(LTBP1)

MUI:	104548323(LTBP1)

PGUU:

104461656(LTBP1)

PLET:

104617393(LTBP1)

CUCA:

104058192(LTBP1)

PCUR:

138718169(LTBP1)

TEO:	104383929(LTBP1)

BREG:

104639963(LTBP1)

GAME:

129204247(LTBP1)

OHA:	104329277(LTBP1)

ACAR:

104517801(LTBP1)

CPEA:

104397298(LTBP1)

CVF:	104282313(LTBP1)

RTD:	128907627(LTBP1)

CRID:

134512914(LTBP1)

LMIC:

141740714(LTBP1)

NARQ:

141477146(LTBP1)

AAM:	106485480(LTBP1)

AROW:

112973415(LTBP1)

NPD:	112957518(LTBP1)

DNE:	112997156(LTBP1)

SCAM:

104151684(LTBP1)

ASN:	102377777(LTBP1)

AMJ:	102577012(LTBP1)

CPOO:

109319879(LTBP1)

GGN:	109304396(LTBP1)

PSS:	102452254(LTBP1)

CIZ:	142010987(LTBP1)

CMY:	102940047(LTBP1)

CCAY:

125633802(LTBP1)

LKP:	140909348(LTBP1)

NDS:	141985166(LTBP1)

DCC:	119853685(LTBP1)

CPIC:

101944302(LTBP1)

TST:	117874608(LTBP1)

EOB:	135876432(LTBP1)

CABI:

116819065

MRV:	120400914(LTBP1)

EMQ:	137162730(LTBP1)

ACS:	100560501(ltbp1)

ASAO:

132761274(LTBP1)

PVT:	110083923 110089038

SUND:

121927513(LTBP1)

PBI:	103056207(LTBP1)

PMUR:

107292894(LTBP1)

CTIG:

120312088(LTBP1)

TSR:	106543053(LTBP1)

PGUT:

117671875(LTBP1)

PCAE:

139308718(LTBP1)

APRI:

131188714(LTBP1)

PTEX:

113433141(LTBP1)

NSS:	113420732(LTBP1)

VKO:	123033925(LTBP1)

PMUA:

114594503(LTBP1)

PRAF:

128410949(LTBP1)

ZVI:	118081797(LTBP1)

HCG:	128348160(LTBP1)

GJA:

107113457

STOW:

125426039(LTBP1)

EMC:	129328111(LTBP1)

XLA:	108716682(ltbp1.L) 398322(ltbp1.S)

XTR:	100488719(ltbp1)

NPR:	108784174(LTBP1)

RTEM:

120937524(LTBP1)

ACAT:

141140487(LTBP1)

PADS:

140329137(LTBP1)

BBUF:

120998744(LTBP1)

BGAR:

122936312(LTBP1)

DTC:	141063520(LTBP1)

PWL:	138295996(LTBP1)

MUO:	115465782(LTBP1)

GSH:	117356998(LTBP1)

DRE:	562072(ltbp1)

SRX:	107744442 107755966

SANH:

107670806 107689790

SGH:	107553384 107583538

CCAR:

109059580(ltbp1) 109070464

CAUA:

113113694(ltbp1) 113117135

CGIB:

127933426 127976137

PTET:

122361933(ltbp1)

LROH:

127179812(ltbp1)

GRF:	141295253(ltbp1)

OMC:	131522965(ltbp1)

PPRM:

120477716(ltbp1)

RKG:	130097427(ltbp1)

MAMB:

125268730(ltbp1)

CIDE:

127498182

CERY:

137006109(ltbp1)

MASI:

127411150 127455548

TROS:

130560114(ltbp1)

TDW:	130436775(ltbp1)

MANU:

129417229(ltbp1)

PDAB:

135727209(ltbp1)

IPU:

108269599

PHYP:

113547718

SMEO:

124389766(ltbp1)

TFD:	113662038(ltbp1)

TVC:	132851967(ltbp1)

CGAR:

128535495(ltbp1)

NGRA:

132894022(ltbp1)

TRN:	134325401(ltbp1)

AMEX:

103040914(ltbp1)

CMAO:

118823246(ltbp1)

EEE:	113591717(ltbp1)

CHAR:

105911544(ltbp1)

SPIL:

134063650(ltbp1)

ASAD:

121685921(ltbp1)

LCO:	104922209(ltbp1)

TBEN:

117476002(ltbp1)

CGOB:

115019866(ltbp1)

PGEO:

117459942(ltbp1)

GACU:

117550644(ltbp1)

EMAC:

134858751(ltbp1)

ELY:	117248146(ltbp1)

EFO:	125903945(ltbp1)

PLEP:

121954359(ltbp1)

SLUC:

116064552

ECRA:

117960581(ltbp1)

ESP:

116705501

PFLV:

114571722(ltbp1)

GAT:	120820574(ltbp1)

PPUG:

119213796(ltbp1)

AFB:	129091971(ltbp1)

CLUM:

117744403(ltbp1)

CANA:

137779566(ltbp1)

CVE:	137885914(ltbp1)

MSAM:

119917373(ltbp1)

SCHU:

122884778(ltbp1)

EARM:

139294660(ltbp1)

CUD:

121511318

SPUL:

138588263(ltbp1)

LMIX:

132975944(ltbp1)

HTC:	141794928(ltbp1)

ASTR:

137603416(ltbp1)

PKLU:

139210527(ltbp1)

MZE:	101477739(ltbp1)

ONL:	100709483(ltbp1)

OAU:	116327394(ltbp1)

OLA:	101172562(ltbp1)

OML:	112140989(ltbp1)

CSAI:

133463658(ltbp1)

XMA:	102219599(ltbp1)

XCO:	114137718(ltbp1)

XHE:	116712875(ltbp1)

PRET:

103476545(ltbp1)

PFOR:

103153118(ltbp1)

PLAI:

106964688(ltbp1)

PMEI:

106903388(ltbp1)

GAF:	122842423(ltbp1)

PPRL:

129359764(ltbp1)

CVG:

107099467

CTUL:

119796169(ltbp1)

GMU:	124858940(ltbp1)

NFU:	107375474(ltbp1)

KMR:	108244575(ltbp1)

ALIM:

106512920

NWH:	119413942(ltbp1)

LTU:	140313465(ltbp1)

AOCE:

111586464(ltbp1)

EJA:	138193682(ltbp1)

BFRE:

138633385(ltbp1)

MCEP:

125018670(ltbp1)

CSEM:

103387703(ltbp1)

POV:	109630437(ltbp1)

SSEN:

122782114 122782121

SSOE:

131473776(ltbp1)

HHIP:

117775288(ltbp1)

HSP:	118118714(ltbp1)

PPLT:

128453702(ltbp1)

SMAU:

118283660(ltbp1)

LCF:

108895767

SDU:	111236410(ltbp1)

SLAL:

111647046(ltbp1)

XGL:	120796302(ltbp1)

HCQ:	109523166(ltbp1)

SSCV:

125978482(ltbp1)

SBIA:

133509385(ltbp1)

PEE:	133410194(ltbp1)

PTAO:

133485381(ltbp1)

BPEC:

110158153(ltbp1)

ENY:

140348240

MALB:

109960055(ltbp1)

BSPL:

114870414(ltbp1)

SJO:	128373337(ltbp1)

SSCO:

133991449(ltbp1)

TTY:	137196609(ltbp1)

GMH:	115559867(ltbp1)

SASA:

100380761(ltbp1) 106576950

STRU:

115153174(ltbp1) 115193820

OTW:	112252967(ltbp1) 112260775

OMY:	110502431 110528297(ltbp1)

OGO:	124038230 124041290

ONE:	115113249(ltbp1) 115135153

OKI:	109888965(ltbp1) 109898846

OKE:	118361335 118369667(ltbp1)

OMM:	135510979 135512355

OCLA:

139381140 139411247

SALP:

111951705 111977916

SNH:	120046547(ltbp1)

SFON:

129836298(ltbp1) 129851269

CCLU:

121553785 121570217

ELS:	105023261(ltbp1)

OEP:	134022191(ltbp1)

SFM:	108918085(ltbp1)

PKI:	111839299(ltbp1)

AANG:

118218321(ltbp1)

AROT:

135244700(ltbp1)

CCOG:

133117956(ltbp1)

LOC:	102698776(ltbp1)

PSPA:

121315676(ltbp1) 121316754

ARUT:

117402566 117411023(ltbp1)

PSEX:

120516446(ltbp1)

LCM:	102355559(LTBP1)

CMK:	103181768(ltbp1)

RTP:	109919065(ltbp1)

CPLA:

122552669(ltbp1)

CPUN:

140454655 140482832(ltbp1)

HOC:	132819679(ltbp1) 132836795

SCAU:

119957724 119975217(ltbp1)

LERI:

129699491(ltbp1)

HAKA:

140730299(ltbp1)

PMRN:

116939416(LTBP1) 116943138 116947099 116948380

LRJ:	133342441 133347038(LTBP1) 133352795 133361722

BFO:

118413602

BBEL:

109476983

SKO:	100329091(LTBP1)

PFLL:

139148902

» show all

Reference

PMID:19431147

Authors

Tritschler I, Gramatzki D, Capper D, Mittelbronn M, Meyermann R, Saharinen J, Wick W, Keski-Oja J, Weller M

Title

Modulation of TGF-beta activity by latent TGF-beta-binding protein 1 in human malignant glioma cells.

Journal

Int J Cancer 125:530-40 (2009)
DOI:10.1002/ijc.24443

Sequence

[hsa:4052]

Reference

PMID:25960420

Authors

Hinz B

Title

The extracellular matrix and transforming growth factor-beta1: Tale of a strained relationship.

Journal

Matrix Biol 47:54-65 (2015)
DOI:10.1016/j.matbio.2015.05.006

Reference

PMID:24204629

Authors

Vittal R, Mickler EA, Fisher AJ, Zhang C, Rothhaar K, Gu H, Brown KM, Emtiazdjoo A, Lott JM, Frye SB, Smith GN, Sandusky GE, Cummings OW, Wilkes DS

Title

Type V collagen induced tolerance suppresses collagen deposition, TGF-beta and associated transcripts in pulmonary fibrosis.

Journal

PLoS One 8:e76451 (2013)
DOI:10.1371/journal.pone.0076451

LinkDB

DBGET integrated database retrieval system