Entry |
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Name |
Regulation of actin cytoskeleton - Ailuropoda melanoleuca (giant panda) |
Class |
Cellular Processes; Cell motility
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Pathway map |
aml04810 | Regulation of actin cytoskeleton |
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Other DBs |
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Organism |
Ailuropoda melanoleuca (giant panda) [GN: aml]
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Gene |
100479986 | FGF2; LOW QUALITY PROTEIN: fibroblast growth factor 2 [KO:K18497] |
100473486 | PDGFA; platelet-derived growth factor subunit A isoform X1 [KO:K04359] |
100475543 | PDGFB; platelet-derived growth factor subunit B isoform X4 [KO:K17386] |
109488507 | CHRM3; muscarinic acetylcholine receptor M3 isoform X1 [KO:K04131] |
100465369 | GNA12; guanine nucleotide-binding protein subunit alpha-12 isoform X1 [KO:K04346] |
100474482 | GNA13; guanine nucleotide-binding protein subunit alpha-13 [KO:K04639] |
100477221 | GNG14; putative guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-14 [KO:K04347] |
100477225 | GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 isoform X1 [KO:K04347] |
100466045 | FGD1; FYVE, RhoGEF and PH domain-containing protein 1 isoform X1 [KO:K05720] |
100474838 | FGD3; FYVE, RhoGEF and PH domain-containing protein 3 isoform X3 [KO:K05722] |
100479448 | BCAR1; breast cancer anti-estrogen resistance protein 1 isoform X2 [KO:K05726] |
100467664 | ARHGEF6; rho guanine nucleotide exchange factor 6 isoform X1 [KO:K05729] |
100463775 | PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1 [KO:K00922] [EC:2.7.1.153] |
100479294 | PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153] |
100479580 | PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform [KO:K00922] [EC:2.7.1.153] |
100475291 | PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta [KO:K02649] |
100483828 | PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649] |
100467916 | PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma [KO:K02649] |
105242089 | TIAM1; T-lymphoma invasion and metastasis-inducing protein 1 isoform X1 [KO:K05731] |
100477081 | ARHGEF1; rho guanine nucleotide exchange factor 1 isoform X1 [KO:K12330] |
100471078 | ARHGEF12; rho guanine nucleotide exchange factor 12 isoform X1 [KO:K07532] |
100468971 | RAC3; ras-related C3 botulinum toxin substrate 3 isoform X1 [KO:K07861] |
100465076 | CDC42; cell division control protein 42 homolog isoform X1 [KO:K04393] |
100479753 | ARHGEF7; rho guanine nucleotide exchange factor 7 isoform X1 [KO:K13710] |
100483995 | PPP1R12A; protein phosphatase 1 regulatory subunit 12A isoform X1 [KO:K06270] |
100470069 | PPP1R12B; protein phosphatase 1 regulatory subunit 12B isoform X8 [KO:K12329] |
100476917 | PPP1R12C; protein phosphatase 1 regulatory subunit 12C [KO:K17457] |
100483724 | MYL2; myosin regulatory light chain 2, ventricular/cardiac muscle isoform [KO:K10351] |
100475493 | MYL7; myosin regulatory light chain 2, atrial isoform [KO:K12754] |
117799888 | myosin regulatory light chain 2, smooth muscle minor isoform-like isoform X1 [KO:K12757] |
100480191 | MYLPF; myosin regulatory light chain 2, skeletal muscle isoform [KO:K12758] |
117799351 | myosin regulatory light chain 2, skeletal muscle isoform-like [KO:K12758] |
100478486 | BAIAP2; brain-specific angiogenesis inhibitor 1-associated protein 2 [KO:K05627] |
100466792 | WASF2; wiskott-Aldrich syndrome protein family member 2 [KO:K05748] |
100475933 | CYFIP2; cytoplasmic FMR1-interacting protein 2 isoform X1 [KO:K05749] |
100467958 | CYFIP1; cytoplasmic FMR1-interacting protein 1 isoform X1 [KO:K05749] |
100478002 | WASF1; wiskott-Aldrich syndrome protein family member 1 isoform X3 [KO:K05753] |
100483279 | ARPC1B; actin-related protein 2/3 complex subunit 1B isoform X1 [KO:K05757] |
100478818 | ARPC5L; actin-related protein 2/3 complex subunit 5-like protein [KO:K05754] |
100471787 | LOW QUALITY PROTEIN: uncharacterized protein LOC100471787 [KO:K05765] |
100467617 | IQGAP3; ras GTPase-activating-like protein IQGAP3 isoform X1 [KO:K05767] |
100482957 | IQGAP2; ras GTPase-activating-like protein IQGAP2 isoform X3 [KO:K05767] |
100465768 | APC2; LOW QUALITY PROTEIN: adenomatous polyposis coli protein 2 [KO:K02085] |
100470646 | ARHGEF4; rho guanine nucleotide exchange factor 4 isoform X1 [KO:K05769] |
100468086 | SPATA13; spermatogenesis-associated protein 13 isoform X7 [KO:K05769] |
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Compound |
C00681 | 1-Acyl-sn-glycerol 3-phosphate |
C04637 | 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate |
C05981 | Phosphatidylinositol-3,4,5-trisphosphate |
C11554 | 1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate |
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Reference |
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Authors |
Burridge K, Wennerberg K. |
Title |
Rho and Rac take center stage. |
Journal |
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Reference |
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Authors |
Schmitz AA, Govek EE, Bottner B, Van Aelst L. |
Title |
Rho GTPases: signaling, migration, and invasion. |
Journal |
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Reference |
|
Authors |
Takai Y, Sasaki T, Matozaki T. |
Title |
Small GTP-binding proteins. |
Journal |
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Reference |
|
Authors |
Pollard TD. |
Title |
The cytoskeleton, cellular motility and the reductionist agenda. |
Journal |
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Reference |
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Authors |
Ridley AJ, Schwartz MA, Burridge K, Firtel RA, Ginsberg MH, Borisy G, Parsons JT, Horwitz AR. |
Title |
Cell migration: integrating signals from front to back. |
Journal |
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Reference |
|
Authors |
Sastry SK, Burridge K. |
Title |
Focal adhesions: a nexus for intracellular signaling and cytoskeletal dynamics. |
Journal |
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Reference |
|
Authors |
Fukata M, Nakagawa M, Kuroda S, Kaibuchi K. |
Title |
Cell adhesion and Rho small GTPases. |
Journal |
J Cell Sci 112 ( Pt 24):4491-500 (1999) |
Related pathway |
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KO pathway |
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LinkDB |
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