KEGG   PATHWAY: hsa00230Help
Entry
hsa00230                    Pathway                                

Name
Purine metabolism - Homo sapiens (human)
Class
Metabolism; Nucleotide metabolism
BRITE hierarchy
Pathway map
hsa00230  Purine metabolism
hsa00230

Ortholog table
Module
hsa_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:hsa00230]
hsa_M00048  Inosine monophosphate biosynthesis, PRPP + glutamine => IMP [PATH:hsa00230]
hsa_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:hsa00230]
hsa_M00050  Guanine ribonucleotide biosynthesis IMP => GDP,GTP [PATH:hsa00230]
Disease
H00184  Hypermethioninemia
H00192  Xanthinuria
H00194  Lesch-Nyhan syndrome
H00195  Adenine phosphoribosyltransferase deficiency
H00196  Phosphoribosylpyrophosphate synthetase I superactivity
H00197  Adenylosuccinate lyase deficiency
H00469  Mitochondrial DNA depletion syndrome (MDS)
H00481  Cone-rod dystrophy and cone dystrophy
H00494  Desbuquois syndrome
H00674  Anemia due to disorders of nucleotide metabolism
H00761  SEMD, Pakistani type
H00824  Calcification of joints and arteries
H00837  Leber congenital amaurosis (LCR)
H00946  Arts syndrome
H00966  AICA-ribosiduria
H01002  Generalized arterial calcification of infancy
H01096  Pyruvate kinase (PK) deficiency
H01118  Progressive external ophthalmoplegia (PEO)
H01128  Reticular dysgenesis
H01394  Cole disease
H01532  Gout
H01570  Autosomal dominant striatal degeneration (ADSD)
Drug
D00155  Pentostatin (JAN/USAN/INN)
D00161  Mercaptopurine (USP)
D00224  Allopurinol (JP17/USP/INN)
D00231  Inamrinone (USP)
D00341  Hydroxyurea (USP)
D00417  Milrinone (JAN/USP/INN)
D00752  Mycophenolate mofetil (JAN/USAN)
D01155  Gemcitabine hydrochloride (JAN/USAN)
D01206  Febuxostat (JAN/USAN/INN)
D01370  Cladribine (JAN/USAN/INN)
D01392  Mizoribine (JP17/INN)
D01896  Cilostazol (JP17/USAN/INN)
D01907  Fludarabine phosphate (JAN/USP)
D02008  Tadalafil (JAN/USAN/INN)
D02042  Olprinone hydrochloride hydrate (JAN)
D02084  Inamrinone ethylenelactate
D02085  Milrinone lactate
D02365  Oxypurinol (USAN)
D02368  Gemcitabine (USAN/INN)
D02933  Anagrelide hydrochloride (USAN)
D02985  Arofylline (USAN/INN)
D03378  Caracemide (USAN)
D03546  Clofarabine (JAN/USAN/INN)
D03657  Dasantafil (USAN/INN)
D04004  Enoximone (USAN/INN)
D04185  Filaminast (USAN/INN)
D04245  Forodesine hydrochloride (JAN/USAN)
D04508  Imazodan hydrochloride (USAN)
D04529  Indolidan (USAN/INN)
D04628  Isomazole hydrochloride (USAN)
D04751  Lixazinone sulfate (USAN)
D04931  Mercaptopurine (INN)
D04936  Merimepodib (USAN/INN)
D05094  Mycophenolate mofetil hydrochloride (USAN)
D05095  Mycophenolate sodium (USP)
D05096  Mycophenolic acid (USAN/INN)
D05400  Pelitrexol (USAN/INN)
D05474  Piclamilast (USAN/INN)
D06109  Thioguanine (USP)
D06130  Tiazofurin (USAN)
D06132  Tibenelast sodium (USAN)
D06575  Catramilast (USAN/INN)
D06596  Forodesine (USAN/INN)
D07455  Anagrelide (INN/BAN)
D07564  Allopurinol sodium
D07966  Fludarabine (INN)
D08294  Olprinone (INN)
D08603  Tioguanine (INN)
D08860  Apremilast (JAN/USAN)
D09020  Tofimilast (INN/USAN)
D09621  Gisadenafil (USAN/INN)
D09622  Gisadenafil besylate (USAN)
D09786  Topiroxostat (JAN/INN)
D09822  Theosalicin (JAN)
D09948  Plecanatide (USAN/INN)
D10222  Gemcitabine elaidate (USAN/INN)
D10255  Anagrelide hydrochloride hydrate (JAN)
D10431  Ulodesine (USAN)
D10432  Ulodesine succinate (USAN)
D10963  Oleclumab (USAN)
D10976  Recanaclotide (USAN/INN)
Other DBs
BSID: 82944
GO: 0042278
Organism
Homo sapiens (human) [GN:hsa]
Gene
53343  NUDT9; nudix hydrolase 9 [KO:K13988] [EC:3.6.1.13]
56985  ADPRM; ADP-ribose/CDP-alcohol diphosphatase, manganese dependent [KO:K01517] [EC:3.6.1.53 3.6.1.16 3.6.1.13]
11164  NUDT5; nudix hydrolase 5 [KO:K13987] [EC:2.7.7.96 3.6.1.- 3.6.1.58 3.6.1.13]
5236  PGM1; phosphoglucomutase 1 [KO:K01835] [EC:5.4.2.2]
55276  PGM2; phosphoglucomutase 2 [KO:K15779] [EC:5.4.2.7 5.4.2.2]
221823  PRPS1L1; phosphoribosyl pyrophosphate synthetase 1-like 1 [KO:K00948] [EC:2.7.6.1]
5634  PRPS2; phosphoribosyl pyrophosphate synthetase 2 [KO:K00948] [EC:2.7.6.1]
5631  PRPS1; phosphoribosyl pyrophosphate synthetase 1 [KO:K00948] [EC:2.7.6.1]
5471  PPAT; phosphoribosyl pyrophosphate amidotransferase [KO:K00764] [EC:2.4.2.14]
2618  GART; phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase [KO:K11787] [EC:6.3.3.1 2.1.2.2 6.3.4.13]
5198  PFAS; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
10606  PAICS; phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01587] [EC:6.3.2.6 4.1.1.21]
158  ADSL; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
471  ATIC; 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:3.5.4.10 2.1.2.3]
353  APRT; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
22978  NT5C2; 5'-nucleotidase, cytosolic II [KO:K01081] [EC:3.1.3.5]
84618  NT5C1A; 5'-nucleotidase, cytosolic IA [KO:K01081] [EC:3.1.3.5]
93034  NT5C1B; 5'-nucleotidase, cytosolic IB [KO:K01081] [EC:3.1.3.5]
30833  NT5C; 5', 3'-nucleotidase, cytosolic [KO:K01081] [EC:3.1.3.5]
56953  NT5M; 5',3'-nucleotidase, mitochondrial [KO:K01081] [EC:3.1.3.5]
51251  NT5C3A; 5'-nucleotidase, cytosolic IIIA [KO:K01081] [EC:3.1.3.5]
115024  NT5C3B; 5'-nucleotidase, cytosolic IIIB [KO:K01081] [EC:3.1.3.5]
100526794  NT5C1B-RDH14; NT5C1B-RDH14 readthrough [KO:K01081] [EC:3.1.3.5]
4907  NT5E; 5'-nucleotidase ecto [KO:K19970] [EC:3.1.3.5]
4860  PNP; purine nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
3251  HPRT1; hypoxanthine phosphoribosyltransferase 1 [KO:K00760] [EC:2.4.2.8]
3614  IMPDH1; inosine monophosphate dehydrogenase 1 [KO:K00088] [EC:1.1.1.205]
3615  IMPDH2; inosine monophosphate dehydrogenase 2 [KO:K00088] [EC:1.1.1.205]
10201  NME6; NME/NM23 nucleoside diphosphate kinase 6 [KO:K00940] [EC:2.7.4.6]
29922  NME7; NME/NM23 family member 7 [KO:K00940] [EC:2.7.4.6]
4831  NME2; NME/NM23 nucleoside diphosphate kinase 2 [KO:K00940] [EC:2.7.4.6]
4833  NME4; NME/NM23 nucleoside diphosphate kinase 4 [KO:K00940] [EC:2.7.4.6]
4830  NME1; NME/NM23 nucleoside diphosphate kinase 1 [KO:K00940] [EC:2.7.4.6]
4832  NME3; NME/NM23 nucleoside diphosphate kinase 3 [KO:K00940] [EC:2.7.4.6]
654364  NME1-NME2; NME1-NME2 readthrough [KO:K00940] [EC:2.7.4.6]
221264  AK9; adenylate kinase 9 [KO:K18533] [EC:2.7.4.6 2.7.4.3]
956  ENTPD3; ectonucleoside triphosphate diphosphohydrolase 3 [KO:K01510] [EC:3.6.1.5]
377841  ENTPD8; ectonucleoside triphosphate diphosphohydrolase 8 [KO:K01510] [EC:3.6.1.5]
953  ENTPD1; ectonucleoside triphosphate diphosphohydrolase 1 [KO:K01510] [EC:3.6.1.5]
124583  CANT1; calcium activated nucleotidase 1 [KO:K12304] [EC:3.6.1.6]
9583  ENTPD4; ectonucleoside triphosphate diphosphohydrolase 4 [KO:K12305] [EC:3.6.1.6]
957  ENTPD5; ectonucleoside triphosphate diphosphohydrolase 5 [KO:K01511] [EC:3.6.1.6]
955  ENTPD6; ectonucleoside triphosphate diphosphohydrolase 6 (putative) [KO:K01511] [EC:3.6.1.6]
131870  NUDT16; nudix hydrolase 16 [KO:K16855] [EC:3.6.1.64 3.6.1.62]
3704  ITPA; inosine triphosphatase [KO:K01519] [EC:3.6.1.-]
7498  XDH; xanthine dehydrogenase [KO:K00106] [EC:1.17.3.2 1.17.1.4]
318  NUDT2; nudix hydrolase 2 [KO:K01518] [EC:3.6.1.17]
8833  GMPS; guanine monophosphate synthase [KO:K01951] [EC:6.3.5.2]
2766  GMPR; guanosine monophosphate reductase [KO:K00364] [EC:1.7.1.7]
51292  GMPR2; guanosine monophosphate reductase 2 [KO:K00364] [EC:1.7.1.7]
9615  GDA; guanine deaminase [KO:K01487] [EC:3.5.4.3]
2987  GUK1; guanylate kinase 1 [KO:K00942] [EC:2.7.4.8]
5315  PKM; pyruvate kinase M1/2 [KO:K00873] [EC:2.7.1.40]
5313  PKLR; pyruvate kinase L/R [KO:K12406] [EC:2.7.1.40]
6240  RRM1; ribonucleotide reductase catalytic subunit M1 [KO:K10807] [EC:1.17.4.1]
50484  RRM2B; ribonucleotide reductase regulatory TP53 inducible subunit M2B [KO:K10808] [EC:1.17.4.1]
6241  RRM2; ribonucleotide reductase regulatory subunit M2 [KO:K10808] [EC:1.17.4.1]
1716  DGUOK; deoxyguanosine kinase [KO:K00904] [EC:2.7.1.113]
25885  POLR1A; RNA polymerase I subunit A [KO:K02999] [EC:2.7.7.6]
84172  POLR1B; RNA polymerase I subunit B [KO:K03002] [EC:2.7.7.6]
30834  ZNRD1; zinc ribbon domain containing 1 [KO:K03000]
221830  TWISTNB; TWIST neighbor [KO:K03004]
64425  POLR1E; RNA polymerase I subunit E [KO:K03005]
5430  POLR2A; RNA polymerase II subunit A [KO:K03006] [EC:2.7.7.6]
5431  POLR2B; RNA polymerase II subunit B [KO:K03010] [EC:2.7.7.6]
5432  POLR2C; RNA polymerase II subunit C [KO:K03011]
5433  POLR2D; RNA polymerase II subunit D [KO:K03012]
5434  POLR2E; RNA polymerase II subunit E [KO:K03013]
5435  POLR2F; RNA polymerase II subunit F [KO:K03014]
5436  POLR2G; RNA polymerase II subunit G [KO:K03015]
5437  POLR2H; RNA polymerase II subunit H [KO:K03016]
5438  POLR2I; RNA polymerase II subunit I [KO:K03017]
5441  POLR2L; RNA polymerase II subunit L [KO:K03007]
5439  POLR2J; RNA polymerase II subunit J [KO:K03008]
548644  POLR2J3; RNA polymerase II subunit J3 [KO:K03008]
246721  POLR2J2; RNA polymerase II subunit J2 [KO:K03008]
5440  POLR2K; RNA polymerase II subunit K [KO:K03009]
11128  POLR3A; RNA polymerase III subunit A [KO:K03018] [EC:2.7.7.6]
55703  POLR3B; RNA polymerase III subunit B [KO:K03021] [EC:2.7.7.6]
10623  POLR3C; RNA polymerase III subunit C [KO:K03023]
661  POLR3D; RNA polymerase III subunit D [KO:K03026]
55718  POLR3E; RNA polymerase III subunit E [KO:K14721]
9533  POLR1C; RNA polymerase I and III subunit C [KO:K03027]
51728  POLR3K; RNA polymerase III subunit K [KO:K03019]
51082  POLR1D; RNA polymerase I and III subunit D [KO:K03020]
171568  POLR3H; RNA polymerase III subunit H [KO:K03022]
84265  POLR3GL; RNA polymerase III subunit G like [KO:K03024]
10622  POLR3G; RNA polymerase III subunit G [KO:K03024]
10621  POLR3F; RNA polymerase III subunit F [KO:K03025]
5422  POLA1; DNA polymerase alpha 1, catalytic subunit [KO:K02320] [EC:2.7.7.7]
23649  POLA2; DNA polymerase alpha 2, accessory subunit [KO:K02321]
5557  PRIM1; DNA primase subunit 1 [KO:K02684] [EC:2.7.7.-]
5558  PRIM2; DNA primase subunit 2 [KO:K02685] [EC:2.7.7.-]
5424  POLD1; DNA polymerase delta 1, catalytic subunit [KO:K02327] [EC:2.7.7.7]
5425  POLD2; DNA polymerase delta 2, accessory subunit [KO:K02328]
10714  POLD3; DNA polymerase delta 3, accessory subunit [KO:K03504]
57804  POLD4; DNA polymerase delta 4, accessory subunit [KO:K03505]
5426  POLE; DNA polymerase epsilon, catalytic subunit [KO:K02324] [EC:2.7.7.7]
5427  POLE2; DNA polymerase epsilon 2, accessory subunit [KO:K02325] [EC:2.7.7.7]
54107  POLE3; DNA polymerase epsilon 3, accessory subunit [KO:K02326] [EC:2.7.7.7]
56655  POLE4; DNA polymerase epsilon 4, accessory subunit [KO:K03506] [EC:2.7.7.7]
374659  HDDC3; HD domain containing 3 [KO:K21138] [EC:3.1.7.2]
58497  PRUNE1; prune exopolyphosphatase 1 [KO:K01514] [EC:3.6.1.11]
107  ADCY1; adenylate cyclase 1 [KO:K08041] [EC:4.6.1.1]
108  ADCY2; adenylate cyclase 2 [KO:K08042] [EC:4.6.1.1]
109  ADCY3; adenylate cyclase 3 [KO:K08043] [EC:4.6.1.1]
196883  ADCY4; adenylate cyclase 4 [KO:K08044] [EC:4.6.1.1]
111  ADCY5; adenylate cyclase 5 [KO:K08045] [EC:4.6.1.1]
112  ADCY6; adenylate cyclase 6 [KO:K08046] [EC:4.6.1.1]
113  ADCY7; adenylate cyclase 7 [KO:K08047] [EC:4.6.1.1]
114  ADCY8; adenylate cyclase 8 [KO:K08048] [EC:4.6.1.1]
115  ADCY9; adenylate cyclase 9 [KO:K08049] [EC:4.6.1.1]
55811  ADCY10; adenylate cyclase 10 [KO:K11265] [EC:4.6.1.1]
2977  GUCY1A2; guanylate cyclase 1 soluble subunit alpha 2 [KO:K12318] [EC:4.6.1.2]
2982  GUCY1A1; guanylate cyclase 1 soluble subunit alpha 1 [KO:K12318] [EC:4.6.1.2]
2983  GUCY1B1; guanylate cyclase 1 soluble subunit beta 1 [KO:K12319] [EC:4.6.1.2]
2984  GUCY2C; guanylate cyclase 2C [KO:K12320] [EC:4.6.1.2]
3000  GUCY2D; guanylate cyclase 2D, retinal [KO:K12321] [EC:4.6.1.2]
2986  GUCY2F; guanylate cyclase 2F, retinal [KO:K12322] [EC:4.6.1.2]
4881  NPR1; natriuretic peptide receptor 1 [KO:K12323] [EC:4.6.1.2]
4882  NPR2; natriuretic peptide receptor 2 [KO:K12324] [EC:4.6.1.2]
5136  PDE1A; phosphodiesterase 1A [KO:K13755] [EC:3.1.4.17]
5153  PDE1B; phosphodiesterase 1B [KO:K13755] [EC:3.1.4.17]
5137  PDE1C; phosphodiesterase 1C [KO:K13755] [EC:3.1.4.17]
5138  PDE2A; phosphodiesterase 2A [KO:K18283] [EC:3.1.4.17]
5139  PDE3A; phosphodiesterase 3A [KO:K19021] [EC:3.1.4.17]
5140  PDE3B; phosphodiesterase 3B [KO:K13296] [EC:3.1.4.17]
8654  PDE5A; phosphodiesterase 5A [KO:K13762] [EC:3.1.4.35]
5145  PDE6A; phosphodiesterase 6A [KO:K08718] [EC:3.1.4.35]
5158  PDE6B; phosphodiesterase 6B [KO:K13756] [EC:3.1.4.35]
5146  PDE6C; phosphodiesterase 6C [KO:K13757] [EC:3.1.4.35]
5147  PDE6D; phosphodiesterase 6D [KO:K13758]
5148  PDE6G; phosphodiesterase 6G [KO:K13759]
5149  PDE6H; phosphodiesterase 6H [KO:K13760]
5152  PDE9A; phosphodiesterase 9A [KO:K13761] [EC:3.1.4.35]
10846  PDE10A; phosphodiesterase 10A [KO:K18438] [EC:3.1.4.35 3.1.4.17]
50940  PDE11A; phosphodiesterase 11A [KO:K13298] [EC:3.1.4.35 3.1.4.17]
122622  ADSSL1; adenylosuccinate synthase like 1 [KO:K01939] [EC:6.3.4.4]
159  ADSS; adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
271  AMPD2; adenosine monophosphate deaminase 2 [KO:K01490] [EC:3.5.4.6]
272  AMPD3; adenosine monophosphate deaminase 3 [KO:K01490] [EC:3.5.4.6]
270  AMPD1; adenosine monophosphate deaminase 1 [KO:K01490] [EC:3.5.4.6]
132  ADK; adenosine kinase [KO:K00856] [EC:2.7.1.20]
1633  DCK; deoxycytidine kinase [KO:K00893] [EC:2.7.1.74]
100  ADA; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
51816  ADA2; adenosine deaminase 2 [KO:K19572] [EC:3.5.4.4]
122481  AK7; adenylate kinase 7 [KO:K00939] [EC:2.7.4.3]
205  AK4; adenylate kinase 4 [KO:K00939] [EC:2.7.4.3]
26289  AK5; adenylate kinase 5 [KO:K00939] [EC:2.7.4.3]
204  AK2; adenylate kinase 2 [KO:K00939] [EC:2.7.4.3]
203  AK1; adenylate kinase 1 [KO:K00939] [EC:2.7.4.3]
390877  adenylate kinase isoenzyme 1-like [KO:K00939] [EC:2.7.4.3]
158067  AK8; adenylate kinase 8 [KO:K00939] [EC:2.7.4.3]
102157402  AK6; adenylate kinase 6 [KO:K18532] [EC:2.7.4.3]
50808  AK3; adenylate kinase 3 [KO:K00944] [EC:2.7.4.10]
954  ENTPD2; ectonucleoside triphosphate diphosphohydrolase 2 [KO:K01509] [EC:3.6.1.3]
84284  NTPCR; nucleoside-triphosphatase, cancer-related [KO:K06928] [EC:3.6.1.15]
87178  PNPT1; polyribonucleotide nucleotidyltransferase 1 [KO:K00962] [EC:2.7.7.8]
5141  PDE4A; phosphodiesterase 4A [KO:K13293] [EC:3.1.4.53]
5142  PDE4B; phosphodiesterase 4B [KO:K13293] [EC:3.1.4.53]
5143  PDE4C; phosphodiesterase 4C [KO:K13293] [EC:3.1.4.53]
5144  PDE4D; phosphodiesterase 4D [KO:K13293] [EC:3.1.4.53]
5150  PDE7A; phosphodiesterase 7A [KO:K18436] [EC:3.1.4.53]
27115  PDE7B; phosphodiesterase 7B [KO:K18436] [EC:3.1.4.53]
8622  PDE8B; phosphodiesterase 8B [KO:K18437] [EC:3.1.4.53]
5151  PDE8A; phosphodiesterase 8A [KO:K18437] [EC:3.1.4.53]
2272  FHIT; fragile histidine triad [KO:K01522] [EC:3.6.1.29]
22875  ENPP4; ectonucleotide pyrophosphatase/phosphodiesterase 4 [KO:K18424] [EC:3.6.1.29]
9060  PAPSS2; 3'-phosphoadenosine 5'-phosphosulfate synthase 2 [KO:K13811] [EC:2.7.1.25 2.7.7.4]
9061  PAPSS1; 3'-phosphoadenosine 5'-phosphosulfate synthase 1 [KO:K13811] [EC:2.7.1.25 2.7.7.4]
5167  ENPP1; ectonucleotide pyrophosphatase/phosphodiesterase 1 [KO:K01513] [EC:3.6.1.9 3.1.4.1]
5169  ENPP3; ectonucleotide pyrophosphatase/phosphodiesterase 3 [KO:K01513] [EC:3.6.1.9 3.1.4.1]
646625  URAD; ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase [KO:K13485] [EC:4.1.1.97]
55821  ALLC; allantoicase [KO:K01477] [EC:3.5.3.4]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
Reference
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
Reference
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
KO pathway
ko00230   
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