KEGG   PATHWAY: uar04024
Entry
uar04024                    Pathway                                
Name
cAMP signaling pathway - Ursus americanus (American black bear)
Description
cAMP is one of the most common and universal second messengers, and its formation is promoted by adenylyl cyclase (AC) activation after ligation of G protein-coupled receptors (GPCRs) by ligands including hormones, neurotransmitters, and other signaling molecules. cAMP regulates pivotal physiologic processes including metabolism, secretion, calcium homeostasis, muscle contraction, cell fate, and gene transcription. cAMP acts directly on three main targets: protein kinase A (PKA), the exchange protein activated by cAMP (Epac), and cyclic nucleotide-gated ion channels (CNGCs). PKA modulates, via phosphorylation, a number of cellular substrates, including transcription factors, ion channels, transporters, exchangers, intracellular Ca2+ -handling proteins, and the contractile machinery. Epac proteins function as guanine nucleotide exchange factors (GEFs) for both Rap1 and Rap2. Various effector proteins, including adaptor proteins implicated in modulation of the actin cytoskeleton, regulators of G proteins of the Rho family, and phospholipases, relay signaling downstream from Rap.
Class
Environmental Information Processing; Signal transduction
Pathway map
uar04024  cAMP signaling pathway
uar04024

Other DBs
GO: 0019933
Organism
Ursus americanus (American black bear) [GN:uar]
Gene
123797396  VIP peptides [KO:K05264]
123786694  CRH; corticoliberin [KO:K05256]
123776172  CGA; glycoprotein hormones alpha chain [KO:K08522]
123776350  LHB; lutropin subunit beta [KO:K08521]
123800721  GPHB5; glycoprotein hormone beta-5 [KO:K25484]
123794929  TSHB; thyrotropin subunit beta [KO:K05251]
123799779  POMC; pro-opiomelanocortin [KO:K05228]
123782958  GCG; pro-glucagon [KO:K05259]
123802885  gastric inhibitory polypeptide [KO:K05258]
123799532  follitropin subunit beta [KO:K05250]
123779108  NPPA; natriuretic peptides A [KO:K12334]
123782079  ADCYAP1; pituitary adenylate cyclase-activating polypeptide [KO:K05262]
123795977  ADRB1; beta-1 adrenergic receptor [KO:K04141]
123803645  ADRB2; beta-2 adrenergic receptor isoform X1 [KO:K04142]
123796326  DRD1; D(1A) dopamine receptor [KO:K04144]
123775803  DRD5; D(1B) dopamine receptor [KO:K05840]
123795611  ADORA2A; LOW QUALITY PROTEIN: adenosine receptor A2a [KO:K04266]
123803672  HTR4; 5-hydroxytryptamine receptor 4 [KO:K04160]
123782447  HTR6; 5-hydroxytryptamine receptor 6 [KO:K04162]
123800669  PTGER2; prostaglandin E2 receptor EP2 subtype [KO:K04259]
123789095  ADCYAP1R1; pituitary adenylate cyclase-activating polypeptide type I receptor isoform X1 [KO:K04587]
123788731  VIPR2; vasoactive intestinal polypeptide receptor 2 isoform X1 [KO:K04590]
123802993  CRHR1; corticotropin-releasing factor receptor 1 [KO:K04578]
123789105  CRHR2; corticotropin-releasing factor receptor 2 isoform X1 [KO:K04579]
123785918  LHCGR; lutropin-choriogonadotropic hormone receptor [KO:K04248]
123798926  TSHR; thyrotropin receptor [KO:K04249]
123803577  MC2R; adrenocorticotropic hormone receptor [KO:K04200]
123784842  GLP1R; glucagon-like peptide 1 receptor [KO:K04581]
123778738  GIPR; gastric inhibitory polypeptide receptor isoform X1 [KO:K04580]
123789886  GPR119; glucose-dependent insulinotropic receptor [KO:K08424]
123786108  FSHR; follicle-stimulating hormone receptor isoform X1 [KO:K04247]
123783587  NPR1; atrial natriuretic peptide receptor 1 isoform X1 [KO:K12323] [EC:4.6.1.2]
123803297  neuroendocrine secretory protein 55 [KO:K04632]
123803290  LOW QUALITY PROTEIN: guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas-like [KO:K04632]
123801589  EDN1; endothelin-1 [KO:K16366]
123793656  EDN2; endothelin-2 [KO:K16367]
123803296  EDN3; endothelin-3 isoform X1 [KO:K05227]
123801303  SST; somatostatin [KO:K05237]
123789581  NPY; pro-neuropeptide Y [KO:K05232]
123799232  GHRL; appetite-regulating hormone [KO:K05254]
123800524  OXT; oxytocin-neurophysin 1 [KO:K05243]
123796499  HTR1B; 5-hydroxytryptamine receptor 1B [KO:K04153]
123782337  HTR1D; 5-hydroxytryptamine receptor 1D [KO:K04153]
123790557  HTR1A; 5-hydroxytryptamine receptor 1A [KO:K04153]
123784336  HTR1F; 5-hydroxytryptamine receptor 1F [KO:K04153]
123776170  HTR1E; 5-hydroxytryptamine receptor 1E [KO:K04153]
123789797  CHRM1; muscarinic acetylcholine receptor M1 [KO:K04129]
123788910  CHRM2; muscarinic acetylcholine receptor M2 [KO:K04130]
123792366  DRD2; D(2) dopamine receptor [KO:K04145]
123781213  GABBR2; LOW QUALITY PROTEIN: gamma-aminobutyric acid type B receptor subunit 2 [KO:K04615]
123796436  GABBR1; gamma-aminobutyric acid type B receptor subunit 1 [KO:K04615]
123785722  ADORA1; adenosine receptor A1 [KO:K04265]
123793233  EDNRA; endothelin-1 receptor [KO:K04197]
123793177  NPY1R; neuropeptide Y receptor type 1 [KO:K04204]
123793783  SSTR1; somatostatin receptor type 1 isoform X1 [KO:K04217]
123803199  SSTR2; somatostatin receptor type 2 [KO:K04218]
123783757  SSTR5; somatostatin receptor type 5 [KO:K04221]
123779633  HCAR1; hydroxycarboxylic acid receptor 1 [KO:K08401]
123779626  LOW QUALITY PROTEIN: hydroxycarboxylic acid receptor 2-like [KO:K08402]
123793884  free fatty acid receptor 2-like isoform X1 [KO:K04328]
123791717  free fatty acid receptor 2-like [KO:K04328]
123802093  SUCNR1; succinate receptor 1 [KO:K10042]
123795316  PTGER3; prostaglandin E2 receptor EP3 subtype isoform X1 [KO:K04260]
123799176  OXTR; oxytocin receptor [KO:K04229]
123786462  GHSR; growth hormone secretagogue receptor type 1 [KO:K04284]
123795104  GNAI3; guanine nucleotide-binding protein G(i) subunit alpha-3 [KO:K04630]
123789354  GNAI1; guanine nucleotide-binding protein G(i) subunit alpha-1 [KO:K04630]
123798684  GNAI2; guanine nucleotide-binding protein G(i) subunit alpha-2 [KO:K04630]
123789481  ADCY1; adenylate cyclase type 1 [KO:K08041] [EC:4.6.1.1]
123791264  ADCY2; adenylate cyclase type 2 isoform X1 [KO:K08042] [EC:4.6.1.1]
123799951  ADCY3; adenylate cyclase type 3 [KO:K08043] [EC:4.6.1.1]
123795737  ADCY4; adenylate cyclase type 4 isoform X1 [KO:K08044] [EC:4.6.1.1]
123802178  ADCY5; adenylate cyclase type 5 [KO:K08045] [EC:4.6.1.1]
123794794  ADCY6; adenylate cyclase type 6 [KO:K08046] [EC:4.6.1.1]
123798393  ADCY7; adenylate cyclase type 7 isoform X1 [KO:K08047] [EC:4.6.1.1]
123801897  ADCY8; adenylate cyclase type 8 [KO:K08048] [EC:4.6.1.1]
123783548  ADCY9; adenylate cyclase type 9 [KO:K08049] [EC:4.6.1.1]
123792175  ADCY10; adenylate cyclase type 10 [KO:K11265] [EC:4.6.1.1]
123779184  adenylate cyclase type 10-like [KO:K11265] [EC:4.6.1.1]
123804009  CNGA1; cGMP-gated cation channel alpha-1 [KO:K04948]
123787682  CNGA2; cyclic nucleotide-gated olfactory channel [KO:K04949]
123776054  CNGA3; cyclic nucleotide-gated cation channel alpha-3 isoform X1 [KO:K04950]
123782774  CNGA4; cyclic nucleotide-gated cation channel alpha-4 [KO:K04951]
123798370  CNGB1; cyclic nucleotide-gated cation channel beta-1 [KO:K04952]
123797684  CNGB3; cyclic nucleotide-gated cation channel beta-3 [KO:K04953]
123785908  CALM2; calmodulin-2 [KO:K02183]
123800842  CALML4; calmodulin-like protein 4 isoform X1 [KO:K02183]
123802291  calmodulin-like [KO:K02183]
123802321  CALML3; calmodulin-like protein 3 [KO:K02183]
123796079  CALML6; calmodulin-like protein 6 [KO:K02183]
123798898  CALM1; calmodulin-1 [KO:K02183]
123778741  CALM3; calmodulin-3 [KO:K02183]
123793341  CAMK2D; calcium/calmodulin-dependent protein kinase type II subunit delta isoform X1 [KO:K04515] [EC:2.7.11.17]
123803651  CAMK2A; calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1 [KO:K04515] [EC:2.7.11.17]
123789460  CAMK2B; calcium/calmodulin-dependent protein kinase type II subunit beta isoform X1 [KO:K04515] [EC:2.7.11.17]
123782837  CAMK2G; calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X1 [KO:K04515] [EC:2.7.11.17]
123779312  CAMK4; calcium/calmodulin-dependent protein kinase type IV [KO:K05869] [EC:2.7.11.17]
123798526  BVES; blood vessel epicardial substance isoform X1 [KO:K21108]
123784027  POPDC2; popeye domain-containing protein 2 isoform X1 [KO:K26206]
123798522  POPDC3; popeye domain-containing protein 3 [KO:K26207]
123776187  KCNK2; potassium channel subfamily K member 2 isoform X1 [KO:K04913]
123794065  HCN2; potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 [KO:K04955]
123790735  HCN4; potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 [KO:K04957]
123801027  ABCC4; ATP-binding cassette sub-family C member 4 isoform X1 [KO:K05673]
123794811  RAPGEF3; rap guanine nucleotide exchange factor 3 isoform X1 [KO:K08014]
123780680  RAPGEF4; rap guanine nucleotide exchange factor 4 isoform X1 [KO:K04351]
123776255  RRAS; ras-related protein R-Ras isoform X1 [KO:K07829]
123791661  RRAS2; ras-related protein R-Ras2 isoform X1 [KO:K07830]
123792197  PLD2; phospholipase D2 [KO:K01115] [EC:3.1.4.4]
123786391  PLD1; phospholipase D1 isoform X1 [KO:K01115] [EC:3.1.4.4]
123800384  PLCE1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1 [KO:K05860] [EC:3.1.4.11]
123800287  MAPK8; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
123788054  MAPK10; mitogen-activated protein kinase 10 isoform X1 [KO:K04440] [EC:2.7.11.24]
123790496  MAPK9; mitogen-activated protein kinase 9 isoform X1 [KO:K04440] [EC:2.7.11.24]
123795072  RAP1A; ras-related protein Rap-1A [KO:K04353]
123787151  RAP1B; ras-related protein Rap-1b [KO:K07836]
123784191  TIAM1; rho guanine nucleotide exchange factor TIAM1 isoform X1 [KO:K05731]
123795136  VAV3; guanine nucleotide exchange factor VAV3 [KO:K05730]
123779019  VAV1; proto-oncogene vav [KO:K05730]
123775750  VAV2; guanine nucleotide exchange factor VAV2 isoform X1 [KO:K05730]
123802589  RAC1; ras-related C3 botulinum toxin substrate 1 [KO:K04392]
123780787  RAC2; ras-related C3 botulinum toxin substrate 2 isoform X1 [KO:K07860]
123777961  RAC3; ras-related C3 botulinum toxin substrate 3 isoform X1 [KO:K07861]
123804163  PAK1; serine/threonine-protein kinase PAK 1 [KO:K04409] [EC:2.7.11.1]
123790219  ARAP3; arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform X1 [KO:K12490]
123780073  RHOA; transforming protein RhoA [KO:K04513]
123775438  AFDN; afadin isoform X1 [KO:K05702]
123786407  PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
123788422  PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
123779078  PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
123800228  PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
123793748  PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1 [KO:K02649]
123779926  PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta [KO:K02649]
123793473  AKT1; RAC-alpha serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
123784096  AKT2; RAC-beta serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
123791373  AKT3; RAC-gamma serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
123788872  BRAF; serine/threonine-protein kinase B-raf isoform X1 [KO:K04365] [EC:2.7.11.1]
123802053  RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1 [KO:K04366] [EC:2.7.11.1]
123800861  MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 isoform X1 [KO:K04368] [EC:2.7.12.2]
123796818  MAP2K2; dual specificity mitogen-activated protein kinase kinase 2 [KO:K04369] [EC:2.7.12.2]
123795639  MAPK1; mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
123784602  MAPK3; mitogen-activated protein kinase 3 [KO:K04371] [EC:2.7.11.24]
123801768  PRKACA; cAMP-dependent protein kinase catalytic subunit alpha [KO:K04345] [EC:2.7.11.11]
123795272  PRKACB; cAMP-dependent protein kinase catalytic subunit beta isoform X1 [KO:K04345] [EC:2.7.11.11]
123779548  PPP1R1B; protein phosphatase 1 regulatory subunit 1B isoform X1 [KO:K15494]
123799882  PPP1CB; serine/threonine-protein phosphatase PP1-beta catalytic subunit [KO:K06269] [EC:3.1.3.16]
123795174  serine/threonine-protein phosphatase PP1-gamma catalytic subunit [KO:K06269] [EC:3.1.3.16]
123778467  PPP1CA; serine/threonine-protein phosphatase PP1-alpha catalytic subunit [KO:K06269] [EC:3.1.3.16]
123779126  PPP1CC; serine/threonine-protein phosphatase PP1-gamma catalytic subunit [KO:K06269] [EC:3.1.3.16]
123798247  CREB1; cyclic AMP-responsive element-binding protein 1 isoform X1 [KO:K05870]
123799579  CREB3L1; cyclic AMP-responsive element-binding protein 3-like protein 1 [KO:K09048]
123781164  CREB3; cyclic AMP-responsive element-binding protein 3 [KO:K09048]
123788905  CREB3L2; cyclic AMP-responsive element-binding protein 3-like protein 2 [KO:K09048]
123796787  CREB3L3; cyclic AMP-responsive element-binding protein 3-like protein 3 isoform X1 [KO:K09048]
123783374  CREB3L4; cyclic AMP-responsive element-binding protein 3-like protein 4 [KO:K09048]
123789128  CREB5; cyclic AMP-responsive element-binding protein 5 isoform X1 [KO:K09047]
123780918  EP300; histone acetyltransferase p300 isoform X1 [KO:K04498] [EC:2.3.1.48]
123783593  CREB-binding protein isoform X1 [KO:K04498] [EC:2.3.1.48]
123799466  BDNF; brain-derived neurotrophic factor [KO:K04355]
123798968  FOS; proto-oncogene c-Fos [KO:K04379]
123795376  JUN; transcription factor AP-1 [KO:K04448]
123789442  GLI3; LOW QUALITY PROTEIN: transcriptional activator GLI3 [KO:K06230]
123787218  GLI1; LOW QUALITY PROTEIN: zinc finger protein GLI1 [KO:K16797]
123781394  PTCH1; protein patched homolog 1 isoform X1 [KO:K06225]
123793247  hedgehog-interacting protein [KO:K06231]
123793902  NFKBIA; NF-kappa-B inhibitor alpha [KO:K04734]
123788912  NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1 [KO:K02580]
123778302  RELA; transcription factor p65 [KO:K04735]
123803143  SOX9; transcription factor SOX-9 [KO:K18435]
123793952  AMH; muellerian-inhibiting factor [KO:K04665]
123780901  PPARA; peroxisome proliferator-activated receptor alpha isoform X1 [KO:K07294]
123802961  ACOX1; peroxisomal acyl-coenzyme A oxidase 1 isoform X1 [KO:K00232] [EC:1.3.3.6]
123779190  ACOX3; peroxisomal acyl-coenzyme A oxidase 3 isoform X1 [KO:K00232] [EC:1.3.3.6]
123787495  NFATC1; nuclear factor of activated T-cells, cytoplasmic 1 isoform X1 [KO:K04446]
123791553  F2R; proteinase-activated receptor 1 [KO:K03914]
123778440  BAD; bcl2-associated agonist of cell death [KO:K02158]
123780404  LIPE; hormone-sensitive lipase isoform X1 [KO:K07188] [EC:3.1.1.79]
123782085  ROCK1; rho-associated protein kinase 1 isoform X1 [KO:K04514] [EC:2.7.11.1]
123778572  ROCK2; rho-associated protein kinase 2 isoform X1 [KO:K17388] [EC:2.7.11.1]
123780848  PPP1R12A; protein phosphatase 1 regulatory subunit 12A isoform X1 [KO:K06270]
123796948  MYL9; myosin regulatory light polypeptide 9 [KO:K12755]
123792997  PLN; cardiac phospholamban [KO:K05852]
123784585  ATP2A1; sarcoplasmic/endoplasmic reticulum calcium ATPase 1 isoform X1 [KO:K05853] [EC:7.2.2.10]
123779203  ATP2A2; sarcoplasmic/endoplasmic reticulum calcium ATPase 2 [KO:K05853] [EC:7.2.2.10]
123776916  ATP2A3; sarcoplasmic/endoplasmic reticulum calcium ATPase 3 isoform X1 [KO:K05853] [EC:7.2.2.10]
123795526  RYR2; ryanodine receptor 2 [KO:K04962]
123796318  GRIN1; glutamate receptor ionotropic, NMDA 1 isoform X1 [KO:K05208]
123783633  GRIN2A; glutamate receptor ionotropic, NMDA 2A [KO:K05209]
123781746  GRIN2B; glutamate receptor ionotropic, NMDA 2B [KO:K05210]
123803192  GRIN2C; glutamate receptor ionotropic, NMDA 2C [KO:K05211]
123776356  GRIN2D; glutamate receptor ionotropic, NMDA 2D [KO:K05212]
123781021  GRIN3A; glutamate receptor ionotropic, NMDA 3A isoform X1 [KO:K05213]
123793962  GRIN3B; glutamate receptor ionotropic, NMDA 3B [KO:K05214]
123788517  GRIA1; glutamate receptor 1 isoform X1 [KO:K05197]
123793191  GRIA2; glutamate receptor 2 [KO:K05198]
123797198  GRIA3; LOW QUALITY PROTEIN: glutamate receptor 3 [KO:K05199]
123792514  GRIA4; glutamate receptor 4 isoform X1 [KO:K05200]
123789030  CFTR; cystic fibrosis transmembrane conductance regulator [KO:K05031] [EC:5.6.1.6]
123795027  ATP1A1; sodium/potassium-transporting ATPase subunit alpha-1 [KO:K01539] [EC:7.2.2.13]
123783365  ATP1A2; sodium/potassium-transporting ATPase subunit alpha-2 [KO:K01539] [EC:7.2.2.13]
123798066  ATP1A3; sodium/potassium-transporting ATPase subunit alpha-3 [KO:K01539] [EC:7.2.2.13]
123783612  sodium/potassium-transporting ATPase subunit alpha-4 [KO:K01539] [EC:7.2.2.13]
123792133  ATP1B2; sodium/potassium-transporting ATPase subunit beta-2 isoform X1 [KO:K01540]
123792376  ATP1B1; sodium/potassium-transporting ATPase subunit beta-1 [KO:K01540]
123788438  ATP1B3; sodium/potassium-transporting ATPase subunit beta-3 [KO:K01540]
123803404  ATP1B4; LOW QUALITY PROTEIN: protein ATP1B4 [KO:K01540]
123792608  sodium/potassium-transporting ATPase subunit gamma-like isoform X1 [KO:K01538]
123791726  FXYD1; phospholemman isoform X1 [KO:K13360]
123782222  SLC9A1; sodium/hydrogen exchanger 1 [KO:K05742]
123779365  ORAI1; calcium release-activated calcium channel protein 1 [KO:K16056]
123785713  ATP2B4; plasma membrane calcium-transporting ATPase 4 isoform X1 [KO:K05850] [EC:7.2.2.10]
123780781  ATP2B1; plasma membrane calcium-transporting ATPase 1 isoform X1 [KO:K05850] [EC:7.2.2.10]
123795574  ATP2B3; LOW QUALITY PROTEIN: plasma membrane calcium-transporting ATPase 3 [KO:K05850] [EC:7.2.2.10]
123799209  ATP2B2; plasma membrane calcium-transporting ATPase 2 isoform X1 [KO:K05850] [EC:7.2.2.10]
123777895  CACNA1C; voltage-dependent L-type calcium channel subunit alpha-1C [KO:K04850]
123798762  CACNA1D; voltage-dependent L-type calcium channel subunit alpha-1D isoform X1 [KO:K04851]
123797184  CACNA1F; voltage-dependent L-type calcium channel subunit alpha-1F isoform X1 [KO:K04853]
123785763  CACNA1S; LOW QUALITY PROTEIN: voltage-dependent L-type calcium channel subunit alpha-1S [KO:K04857]
123781714  PDE3A; cGMP-inhibited 3',5'-cyclic phosphodiesterase A isoform X1 [KO:K19021] [EC:3.1.4.17]
123791665  PDE3B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B isoform X1 [KO:K13296] [EC:3.1.4.17]
123779985  PDE4C; cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform X1 [KO:K13293] [EC:3.1.4.53]
123795342  PDE4B; cAMP-specific 3',5'-cyclic phosphodiesterase 4B [KO:K13293] [EC:3.1.4.53]
123790545  PDE4D; cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [KO:K13293] [EC:3.1.4.53]
123777565  PDE4A; cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform X1 [KO:K13293] [EC:3.1.4.53]
123797530  PDE10A; cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A [KO:K18438] [EC:3.1.4.17 3.1.4.35]
Compound
C00020  AMP
C00042  Succinate
C00076  Calcium cation
C00080  H+
C00165  Diacylglycerol
C00186  (S)-Lactate
C00212  Adenosine
C00238  Potassium cation
C00288  HCO3-
C00334  4-Aminobutanoate
C00416  Phosphatidate
C00547  L-Noradrenaline
C00575  3',5'-Cyclic AMP
C00584  Prostaglandin E2
C00698  Cl-
C00780  Serotonin
C00788  L-Adrenaline
C01089  (R)-3-Hydroxybutanoate
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01312  Prostaglandin I2
C01330  Sodium cation
C01996  Acetylcholine
C03758  Dopamine
C20792  Oleoylethanolamide
C20793  3-Hydroxyoctanoate
Reference
PMID:11493633
  Authors
Fimia GM, Sassone-Corsi P
  Title
Cyclic AMP signalling.
  Journal
J Cell Sci 114:1971-2 (2001)
Reference
PMID:18323530
  Authors
Serezani CH, Ballinger MN, Aronoff DM, Peters-Golden M
  Title
Cyclic AMP: master regulator of innate immune cell function.
  Journal
Am J Respir Cell Mol Biol 39:127-32 (2008)
DOI:10.1165/rcmb.2008-0091TR
Reference
PMID:24281338
  Authors
Oldenburger A, Maarsingh H, Schmidt M
  Title
Multiple facets of cAMP signalling and physiological impact: cAMP compartmentalization in the lung.
  Journal
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Related
pathway
uar00071  Fatty acid degradation
uar04015  Rap1 signaling pathway
uar04020  Calcium signaling pathway
uar04151  PI3K-Akt signaling pathway
uar04210  Apoptosis
uar04260  Cardiac muscle contraction
uar04340  Hedgehog signaling pathway
uar04720  Long-term potentiation
uar04740  Olfactory transduction
uar04972  Pancreatic secretion
uar04976  Bile secretion
KO pathway
ko04024   
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