KEGG   PATHWAY: xla04820
Entry
xla04820                    Pathway                                
Name
Cytoskeleton in muscle cells - Xenopus laevis (African clawed frog)
Class
Cellular Processes; Cell motility
Pathway map
xla04820  Cytoskeleton in muscle cells
xla04820

Organism
Xenopus laevis (African clawed frog) [GN:xla]
Gene
380419  col1a2.L; collagen type I alpha 2 L homeolog precursor [KO:K06236]
380515  col1a1.S; collagen, type I, alpha 1 S homeolog precursor [KO:K06236]
108700840  col1a1.L; collagen alpha-1(I) chain [KO:K06236]
108719903  col1a2.S; collagen alpha-2(I) chain [KO:K06236]
108701482  col3a1.L; collagen alpha-1(III) chain [KO:K19720]
398983  col3a1.S; collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant) S homeolog precursor [KO:K19720]
108715007  col11a1.S; collagen alpha-1(XI) chain isoform X1 [KO:K19721]
108713331  col5a3.S; collagen alpha-1(XI) chain isoform X1 [KO:K19721]
108711695  col5a3.L; collagen alpha-1(XI) chain isoform X1 [KO:K19721]
108700220  collagen alpha-2(XI) chain isoform X1 [KO:K19721]
398739  col5a1.L; collagen alpha-1(V) chain isoform X1 [KO:K19721]
108699891  collagen alpha-1(I) chain isoform X4 [KO:K19721]
108698165  collagen alpha-1(I) chain isoform X1 [KO:K19721]
108703076  col5a2.S; collagen alpha-2(V) chain [KO:K19721]
108705040  col27a1.L; collagen alpha-1(XXVII) chain B isoform X1 [KO:K19721]
108699914  col5a1.S; collagen alpha-1(V) chain isoform X1 [KO:K19721]
108699974  col27a1.S; collagen alpha-1(XXVII) chain B isoform X1 [KO:K19721]
108701483  col5a2.L; collagen alpha-2(V) chain [KO:K19721]
108714172  col24a1.L; collagen alpha-1(XXIV) chain [KO:K19721]
108714428  col11a1.L; collagen alpha-1(XI) chain isoform X1 [KO:K19721]
446508  col9a3.L; collagen, type IX, alpha 3 L homeolog precursor [KO:K08131]
446631  col9a1.L; collagen, type IX, alpha 1 L homeolog precursor [KO:K08131]
734362  col9a2.L; collagen, type IX, alpha 2 L homeolog precursor [KO:K08131]
108702653  col9a3.S; collagen alpha-3(IX) chain [KO:K08131]
398560  col9a1-b; collagen alpha-1(IX) chain isoform X1 [KO:K08131]
108709589  col9a2.S; collagen alpha-2(IX) chain [KO:K08131]
444234  dcn.S; decorin S homeolog precursor [KO:K04660]
447482  dcn.L; decorin L homeolog precursor [KO:K04660]
100037127  vcan.L; versican L homeolog [KO:K06793]
108707243  versican core protein isoform X1 [KO:K06793]
108708883  elastin-like [KO:K14211]
108707996  eln1.L; elastin isoform X1 [KO:K14211]
380129  col6a1.L; collagen alpha-1(VI) chain [KO:K06238]
734275  col6a2.L; uncharacterized protein LOC734275 precursor [KO:K06238]
108703023  col6a1.S; collagen alpha-1(VI) chain-like [KO:K06238]
108703024  col6a2.S; collagen alpha-2(VI) chain [KO:K06238]
108718494  col6a5.L; collagen alpha-6(VI) chain [KO:K06238]
108702277  collagen alpha-3(VI) chain [KO:K06238]
108702278  collagen alpha-3(VI) chain isoform X1 [KO:K06238]
108719692  col6a6.S; collagen alpha-6(VI) chain [KO:K06238]
108718495  col6a6.L; collagen alpha-6(VI) chain [KO:K06238]
398368  collagen alpha-3(VI) chain isoform X3 [KO:K06238]
379508  thbs1.L; thrombospondin 1 L homeolog precursor [KO:K16857]
779026  thbs1.S; thrombospondin-1 [KO:K16857]
380339  thbs3.L; thrombospondin 3 L homeolog precursor [KO:K04659]
446985  thbs4.S; thrombospondin 4 S homeolog precursor [KO:K04659]
397943  thbs4.L; thrombospondin-4 precursor [KO:K04659]
108700446  thbs3.S; thrombospondin-3 isoform X1 [KO:K04659]
108716699  thbs2.L; thrombospondin-2 [KO:K04659]
108706910  comp.S; cartilage oligomeric matrix protein [KO:K04659]
108695262  comp.L; cartilage oligomeric matrix protein [KO:K04659]
108717845  thbs2.S; thrombospondin-2 [KO:K04659]
108712909  fbn1.S; fibrillin-1 [KO:K06825]
108711397  fbn1.L; fibrillin-1 [KO:K06825]
108706791  fbn3.S; fibrillin-2 isoform X1 [KO:K23342]
108707192  fbn2.S; fibrillin-2 [KO:K23342]
108717258  fbn2.L; fibrillin-2 [KO:K23342]
734223  fbn3.L; fibrillin-2 isoform X1 [KO:K23342]
108700099  collagen alpha-6(IV) chain isoform X3 [KO:K06237]
373763  col4a2.L; collagen alpha-2(IV) chain [KO:K06237]
108709739  collagen alpha-1(IV) chain-like [KO:K06237]
108698394  col4a6.L; collagen alpha-6(IV) chain isoform X1 [KO:K06237]
108700098  col4a5.S; collagen alpha-5(IV) chain isoform X2 [KO:K06237]
108709738  col4a2.S; collagen alpha-2(IV) chain isoform X1 [KO:K06237]
373764  col4a1.L; collagen alpha-1(IV) chain [KO:K06237]
108698395  col4a5.L; collagen alpha-5(IV) chain isoform X1 [KO:K06237]
734480  fbln1.L; fibulin 1 L homeolog precursor [KO:K17307]
108714618  fbln2.L; fibulin-2 isoform X1 [KO:K17307]
108715035  fibulin-2 [KO:K17307]
108696836  hspg2.L; basement membrane-specific heparan sulfate proteoglycan core protein isoform X1 [KO:K06255]
495003  nid2.L; nidogen 2 L homeolog precursor [KO:K06826]
108699786  nid2.S; nidogen-2 [KO:K06826]
108717903  nid1.S; nidogen-1 [KO:K06826]
108716745  nid1.L; nidogen-1 isoform X1 [KO:K06826]
397744  fn1.S; fibronectin precursor [KO:K05717]
121393057  fibronectin-like isoform X1 [KO:K05717]
108718258  syndecan-3 isoform X1 [KO:K06257]
398348  sdc1.L; syndecan-3 [KO:K06257]
394283  sdc2.S; syndecan-2-B precursor [KO:K16336]
379912  sdc2.L; syndecan-2-A precursor [KO:K16336]
378553  sdc3.L; syndecan 3 L homeolog precursor [KO:K16337]
108709562  sdc3.S; syndecan-3 [KO:K16337]
734219  sdc4.L; syndecan 4-B precursor [KO:K16338]
734218  sdc4.S; syndecan 4-A precursor [KO:K16338]
108697619  agrin isoform X4 [KO:K06254]
108696525  agrin isoform X1 [KO:K06254]
399351  bgn.L; biglycan [KO:K08118]
444695  bgn.S; biglycan S homeolog precursor [KO:K08118]
108719229  dsc3.L; desmocollin-2 [KO:K07601]
108719230  dsg2.L; desmoglein-2 [KO:K07597]
108695275  dsg2.S; desmoglein-2 [KO:K07597]
443776  pkp2.L; plakophilin 2 L homeolog [KO:K12642]
108712244  pkp2.S; plakophilin-2 [KO:K12642]
399278  jup.S; junction plakoglobin [KO:K10056]
398496  jup.L; junction plakoglobin-like [KO:K10056]
398354  dsp.L; desmoplakin isoform X1 [KO:K10381]
386600  vim.S; vimentin-4 [KO:K07606]
386601  vim.L; vimentin-1/2 [KO:K07606]
108697828  vimentin [KO:K07606]
108706522  vimentin [KO:K07606]
379869  des.1.S; desmin [KO:K07610]
446868  des.1.L; desmin, gene 1 L homeolog [KO:K07610]
733312  des.2.S; desmin [KO:K07610]
100126634  des.2.L; desmin [KO:K07610]
108718546  laminin subunit alpha-1 [KO:K05637]
108716137  laminin subunit alpha-2-like [KO:K05637]
108705398  itga1.S; integrin alpha-1 [KO:K06480]
108718392  LOW QUALITY PROTEIN: integrin alpha-1-like [KO:K06480]
373743  itga2.L; integrin alpha-2 [KO:K06481]
495051  itga2b.2.L; integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41), gene 2 L homeolog precursor [KO:K06476]
100191022  itga2b.1.S; integrin subunit alpha 2b S homeolog precursor [KO:K06476]
373657  itga3.L; integrin alpha-3 [KO:K06482]
108702534  itga3.S; integrin alpha-3 isoform X2 [KO:K06482]
397839  itga4.S; integrin alpha-4 precursor [KO:K06483]
108701397  itga4.L; integrin alpha-4-like [KO:K06483]
394366  itga5.L; integrin alpha-5 precursor [KO:K06484]
397842  itga5.S; integrin alpha-5-like isoform X1 [KO:K06484]
108702994  itga6.S; integrin alpha-6 isoform X1 [KO:K06485]
397985  itga6.L; integrin alpha-6 isoform X1 [KO:K06485]
108708991  itga7.S; integrin alpha-7 isoform X1 [KO:K06583]
108708560  itga7.L; integrin alpha-7 isoform X2 [KO:K06583]
108719885  itga8.S; integrin alpha-8 [KO:K06584]
108718824  itga8.L; integrin alpha-8 [KO:K06584]
108719000  itga9.L; integrin alpha-9 [KO:K06585]
108699602  itga10.L; integrin alpha-10 [KO:K06586]
378559  itga11.S; integrin alpha-11 [KO:K06587]
108711510  itga11.L; integrin alpha-11 [KO:K06587]
397997  itgav.L; integrin subunit alpha V L homeolog precursor [KO:K06487]
397755  itgb1.L; integrin beta-1-A precursor [KO:K05719]
399443  itgb1.S; integrin beta-1-B precursor [KO:K05719]
397699  itgb3.L; integrin beta-3 isoform X1 [KO:K06493]
108701118  itgb4.L; integrin beta-4 isoform X1 [KO:K06525]
108702819  itgb4.S; integrin beta-4 isoform X2 [KO:K06525]
446423  itgb5.L; integrin subunit beta 5 L homeolog precursor [KO:K06588]
108702890  itgb5.S; integrin beta-5 isoform X1 [KO:K06588]
378686  itgb6.L; integrin beta-6 isoform X1 [KO:K06589]
108708650  itgb7.L; integrin beta-7 [KO:K06590]
108719918  itgb8.S; integrin beta-8 [KO:K06591]
108718868  itgb8.L; integrin beta-8 [KO:K06591]
108712994  talin-2 isoform X2 [KO:K06271]
100037170  tln2.S; talin 2 S homeolog [KO:K06271]
108711290  talin-2 isoform X2 [KO:K06271]
733283  talin-1 isoform X1 [KO:K06271]
373770  vcl.S; vinculin isoform X2 [KO:K05700]
108715125  alpha-actinin-3 [KO:K21073]
432169  actn2.S; actinin alpha 2 S homeolog [KO:K21073]
446326  actn3.L; actinin alpha 3 (gene/pseudogene) L homeolog [KO:K21073]
446752  actn2.L; alpha-actinin-2 [KO:K21073]
100337595  actg1.S; actin, cytoplasmic type 5 [KO:K05692]
734918  actg1.L; actin, cytoplasmic type 8 [KO:K05692]
108703086  actb.S; actin, cytoplasmic 1 [KO:K05692]
398459  actb.L; actin, cytoplasmic 1 [KO:K05692]
398500  dag1.L; dystroglycan 1 L homeolog precursor [KO:K06265]
380447  dag1.S; dystroglycan 1 S homeolog precursor [KO:K06265]
108700839  sgca.L; epsilon-sarcoglycan isoform X1 [KO:K12565]
108718481  sgce.L; epsilon-sarcoglycan isoform X1 [KO:K27061]
100127262  sgcb.L; sarcoglycan beta L homeolog [KO:K12566]
108706588  sgcb.S; beta-sarcoglycan [KO:K12566]
108712261  sgcd.S; delta-sarcoglycan [KO:K12563]
108710815  sgcd.L; delta-sarcoglycan [KO:K12563]
108708720  sgcg.L; gamma-sarcoglycan isoform X3 [KO:K12564]
108709969  sgcg.S; gamma-sarcoglycan isoform X1 [KO:K12564]
108698593  sgcz.L; zeta-sarcoglycan [KO:K27062]
108706601  sgcz.S; zeta-sarcoglycan [KO:K27062]
495447  sspn.S; sarcospan S homeolog [KO:K22194]
496157  snta1.L; syntrophin, alpha 1 L homeolog [KO:K24063]
108702777  snta1.S; alpha-1-syntrophin [KO:K24063]
108719398  sntb1.L; beta-1-syntrophin [KO:K24064]
108715428  beta-2-syntrophin [KO:K24064]
108695430  sntb1.S; beta-1-syntrophin [KO:K24064]
108714066  sntb2.L; beta-2-syntrophin [KO:K24064]
414490  dtna.S; uncharacterized protein LOC414490 [KO:K26998]
373790  dtna.L; dystrobrevin alpha L homeolog [KO:K26998]
734178  flnc.L; filamin-C isoform X4 [KO:K27393]
733321  filamin-C isoform X1 [KO:K27393]
398583  atp1a1.S; ATPase Na+/K+ transporting subunit alpha 1 S homeolog [KO:K01539] [EC:7.2.2.13]
399285  atp1a1.L; sodium/potassium-transporting ATPase subunit alpha-1 [KO:K01539] [EC:7.2.2.13]
398752  atp1a2.S; ATPase, Na+/K+ transporting, alpha 2 polypeptide S homeolog [KO:K01539] [EC:7.2.2.13]
380132  atp1a3.L; Na+/K+ -ATPase alpha 3 subunit [KO:K01539] [EC:7.2.2.13]
108697760  sodium/potassium-transporting ATPase subunit alpha-3 [KO:K01539] [EC:7.2.2.13]
108699431  atp1a2.L; sodium/potassium-transporting ATPase subunit alpha-2 isoform X1 [KO:K01539] [EC:7.2.2.13]
444626  atp1b2.S; ATPase, Na+/K+ transporting, beta 2 polypeptide S homeolog [KO:K01540]
379920  atp1b1.S; ATPase Na+/K+ transporting subunit beta 1 S homeolog [KO:K01540]
735041  atp1b4.L; protein ATP1B4 [KO:K01540]
397733  atp1b3.S; sodium/potassium-transporting ATPase subunit beta-3 [KO:K01540]
379345  atp1b3.L; ATPase Na+/K+ transporting subunit beta 3 L homeolog [KO:K01540]
380054  atp1b2.L; Na+/K+ -ATPase beta 2 subunit [KO:K01540]
108700091  LOW QUALITY PROTEIN: protein ATP1B4-like [KO:K01540]
108708208  atp1b1.L; sodium/potassium-transporting ATPase subunit beta-1 [KO:K01540]
108696078  ankyrin-3 isoform X38 [KO:K09259]
108697176  ankyrin-3 [KO:K09259]
373724  sptan1.S; spectrin alpha chain, non-erythrocytic 1 isoform X1 [KO:K06114]
373718  sptan1.L; spectrin alpha chain, non-erythrocytic 1 isoform X1 [KO:K06114]
108716412  sptbn1.L; spectrin beta chain, non-erythrocytic 1 isoform X1 [KO:K06115]
108700575  spectrin beta chain, non-erythrocytic 4-like [KO:K06115]
108698979  sptbn5.L; spectrin beta chain, non-erythrocytic 5 [KO:K06115]
108717395  sptbn1.S; spectrin beta chain, non-erythrocytic 1 isoform X1 [KO:K06115]
108698614  spectrin beta chain, non-erythrocytic 4 isoform X2 [KO:K06115]
398511  sptbn2.L; spectrin beta chain, non-erythrocytic 1 isoform X1 [KO:K23932]
108715130  spectrin beta chain, non-erythrocytic 1 isoform X1 [KO:K23932]
373825  csrp3.L; cysteine and glycine rich protein 3 L homeolog [KO:K09377]
447622  csrp1.L; cysteine and glycine rich protein 1 L homeolog [KO:K09377]
447266  csrp2.L; cysteine and glycine rich protein 2 L homeolog [KO:K09377]
447493  csrp2.S; cysteine and glycine rich protein 2 S homeolog [KO:K09377]
108698244  myosin-4 [KO:K24220]
108698887  myosin-4 [KO:K24220]
108698976  myosin-4 [KO:K24220]
108698977  myosin-1B [KO:K24220]
108700301  myh13.S; myosin-4 [KO:K24220]
108700302  myosin-4 [KO:K24220]
108701194  myosin-3 [KO:K24220]
108701196  myosin-1B [KO:K24220]
108701197  myosin-4 [KO:K24220]
108701817  myosin-4 [KO:K24220]
108702858  myosin-1B [KO:K24220]
108702859  myosin-4 [KO:K24220]
378671  myh3.S; myosin-1B [KO:K24220]
399414  myh8.L; myosin-4 [KO:K24220]
108701818  myosin-4 [KO:K24220]
108702765  myh7b.S; myosin-7B [KO:K24220]
108698090  myosin-4 [KO:K24220]
108701067  myosin-7B [KO:K24220]
432231  myh15.L; myosin, heavy polypeptide 15 [KO:K24220]
100381200  myh4.L; myosin-4 [KO:K24220]
432141  myh6.S; myosin, heavy chain 6, cardiac muscle, alpha S homeolog [KO:K17751]
108714867  myh6.L; myosin-6 isoform X1 [KO:K17751]
108714868  LOW QUALITY PROTEIN: myosin-7-like [KO:K17751]
108707020  myosin-7 [KO:K17751]
398083  myh9.L; myosin-9 [KO:K10352]
399266  myh10.S; myosin, heavy chain 10, non-muscle S homeolog [KO:K10352]
398719  myh9.S; myosin-9 [KO:K10352]
108701185  myosin-10-like [KO:K10352]
495286  myh11.L; myosin-11 isoform X2 [KO:K10352]
443585  myosin-10 isoform X6 [KO:K10352]
100216329  myh11.S; myosin-11 isoform X2 [KO:K10352]
108696665  myosin-10 isoform X6 [KO:K10352]
379145  myl1.S; uncharacterized protein LOC379145 [KO:K05738]
379944  myl1.L; myosin light chain 1 L homeolog [KO:K05738]
447397  myl6.L; myosin light chain 6 L homeolog [KO:K05738]
398607  myl3.S; myosin light chain 3 S homeolog [KO:K12749]
373844  myl4.L; myosin light chain 4 L homeolog [KO:K12750]
100037107  myl4.S; uncharacterized protein LOC100037107 [KO:K12750]
447131  myl2.S; myosin light chain 2 S homeolog [KO:K10351]
108697104  myl2.L; myosin regulatory light chain 2, ventricular/cardiac muscle isoform [KO:K10351]
380007  mylc2a; myosin light chain, regulatory A [KO:K12754]
108712731  myl7.S; myosin regulatory light chain 2, atrial isoform [KO:K12754]
446851  myl9.L; myosin light chain 9 L homeolog [KO:K12755]
447704  myl9.S; myosin light chain 9 S homeolog [KO:K12755]
399251  mylpf.L; myosin light chain, phosphorylatable, fast skeletal muscle L homeolog [KO:K12758]
108701718  myosin regulatory light chain 2, skeletal muscle isoform type 2 [KO:K12758]
108712385  mybpc1.S; myosin-binding protein C, slow-type isoform X1 [KO:K12557]
108710244  mybpc1.L; myosin-binding protein C, slow-type isoform X1 [KO:K12557]
108697262  myosin-binding protein C, fast-type isoform X1 [KO:K12558]
108695905  myosin-binding protein C, fast-type isoform X1 [KO:K12558]
398261  mybpc3.S; myosin binding protein C3 S homeolog [KO:K12568]
108713456  mybpc3.L; myosin-binding protein C, cardiac-type isoform X1 [KO:K12568]
398625  mybph.S; myosin binding protein H S homeolog [KO:K24494]
398426  acta4.S; actin, striated muscle 3 S homeolog [KO:K10354]
432314  acta1.S; actin, alpha skeletal muscle S homeolog [KO:K12314]
108716753  acta1.L; actin, alpha cardiac muscle 2 [KO:K12314]
779129  MGC75582.S; actin, alpha skeletal muscle 2 [KO:K12314]
379752  actc1.L; actin, alpha cardiac muscle 1 [KO:K12314]
108699710  actc1.S; actin, alpha cardiac muscle 1 [KO:K12314]
779096  acta4.L; actin alpha 4 L homeolog [KO:K12314]
379351  MGC75582.L; MGC75582, possible similarity to act2 L homeolog [KO:K12314]
379410  tnnc1.S; troponin C1, slow skeletal and cardiac typeS homeolog [KO:K05865]
399104  tnnc1.L; troponin C1, slow skeletal and cardiac type L homeolog [KO:K05865]
100037198  tnni1.S; troponin I1, slow skeletal type S homeolog [KO:K10371]
379471  tnni1.2.L; troponin I type 1 (skeletal, slow), gene 2 L homeolog [KO:K10371]
444293  MGC80947 protein [KO:K10371]
444636  tnnt1.S; troponin T1, slow skeletal type S homeolog [KO:K10372]
108696669  tnnt1.L; troponin T, slow skeletal muscle isoform X1 [KO:K10372]
379085  tnnc2.L; troponin C2, fast skeletal type L homeolog [KO:K12042]
379095  tnnc2.S; troponin C2, fast skeletal type S homeolog [KO:K12042]
379243  tnni2.S; troponin I2, fast skeletal type S homeolog [KO:K12043]
108713830  tnni2.L; troponin I, fast skeletal muscle [KO:K12043]
380095  tnnt3.S; troponin T3, fast skeletal type S homeolog [KO:K12046]
100158366  tnnt3.L; troponin T3, fast skeletal type L homeolog [KO:K12046]
397803  tnni3.S; troponin I, cardiac muscle [KO:K12044]
494826  tnni3.L; troponin I3, cardiac type L homeolog [KO:K12044]
398518  tnnt2.L; troponin T2, cardiac type L homeolog [KO:K12045]
446916  troponin T, cardiac muscle isoforms isoform X1 [KO:K12045]
100189579  tpm1.L; tropomyosin 1 L homeolog [KO:K10373]
379445  tpm2.S; tropomyosin 2 b isoform 1 [KO:K10374]
100335131  tpm2.L; tropomyosin 2 a isoform 2 [KO:K10374]
398952  tpm3.S; uncharacterized protein LOC398952 [KO:K09290]
399420  tpm3.L; tropomyosin alpha-3 chain isoform X1 [KO:K09290]
397944  tropomyosin alpha-1 chain-like isoform X1 [KO:K09290]
379628  tpm4.S; tropomyosin 4 S homeolog [KO:K10375]
379469  tpm4.L; tropomyosin 4 L homeolog [KO:K10375]
108701391  titin isoform X1 [KO:K12567] [EC:2.7.11.1]
108701392  muscle M-line assembly protein unc-89-like [KO:K12567] [EC:2.7.11.1]
108702272  titin isoform X1 [KO:K12567] [EC:2.7.11.1]
108713287  myot.S; myotilin [KO:K19875]
108710903  myot.L; myotilin [KO:K19875]
100381005  tcap.S; telethonin [KO:K19879]
108700776  tcap.L; telethonin [KO:K19879]
108701841  neb.L; nebulin isoform X1 [KO:K18267]
108702957  neb.S; nebulin isoform X1 [KO:K18267]
100127275  nebl.S; nebulette isoform X1 [KO:K25865]
495167  nebl.L; nebulette [KO:K25865]
379144  myoz1.S; myozenin 1 S homeolog [KO:K26050]
494787  myoz2.L; myozenin 2 L homeolog [KO:K26050]
108712636  myoz3.S; myozenin-3 [KO:K26050]
380065  myoz2.S; myozenin 2 S homeolog [KO:K26050]
380194  myoz1.L; myozenin 1 L homeolog [KO:K26050]
108710824  myoz3.L; myozenin-3 [KO:K26050]
108706616  pdlim3.S; PDZ and LIM domain protein 3-like isoform X1 [KO:K23353]
108713278  pdlim4.S; PDZ and LIM domain protein 4 [KO:K23353]
398461  pdlim1.S; PDZ and LIM domain 1 S homeolog [KO:K23353]
398648  pdlim1.L; PDZ and LIM domain 1 L homeolog [KO:K23353]
444755  pdlim3.L; PDZ and LIM domain protein 3 [KO:K23353]
446969  pdlim4.L; PDZ and LIM domain 4 L homeolog [KO:K23353]
398962  capza1.L; F-actin-capping protein subunit alpha-1 [KO:K10364]
443925  capza2.L; capping actin protein of muscle Z-line subunit alpha 2 L homeolog [KO:K10364]
108713108  capza2.S; F-actin-capping protein subunit alpha-2 [KO:K10364]
379808  capzb.S; capping actin protein of muscle Z-line subunit beta S homeolog [KO:K10365]
108696857  capzb.L; F-actin-capping protein subunit beta isoforms 1 and 2 isoform X1 [KO:K10365]
108719658  xirp1.S; xin actin-binding repeat-containing protein 1 [KO:K27381]
108702980  xirp2.S; xin actin-binding repeat-containing protein 2 isoform X3 [KO:K27381]
108701358  xirp2.L; xin actin-binding repeat-containing protein 2 isoform X1 [KO:K27381]
108718715  xirp1.L; xin actin-binding repeat-containing protein 1 isoform X3 [KO:K27381]
108696000  nrap.L; nebulin-related-anchoring protein isoform X1 [KO:K24421]
108697449  mypn.S; myopalladin isoform X2 [KO:K22028]
108696202  mypn.L; myopalladin isoform X1 [KO:K22028]
108696280  LIM domain-binding protein 3 isoform X6 [KO:K19867]
379929  ldb3.S; LIM domain binding 3 S homeolog [KO:K19867]
100101292  pdlim5.L; PDZ and LIM domain 5 L homeolog [KO:K19867]
108710972  PDZ and LIM domain protein 7-like [KO:K19867]
379934  tmod3.S; tropomodulin 3 S homeolog [KO:K10370]
100125668  tmod3.L; tropomodulin 3 L homeolog [KO:K10370]
447190  tmod4.L; tropomodulin 4 L homeolog [KO:K10370]
108700376  tmod4.S; tropomodulin-4 [KO:K10370]
108711389  tmod2.L; tropomodulin-2 isoform X1 [KO:K10370]
108713374  tmod1.L; tropomodulin-1 isoform X1 [KO:K10370]
108706915  tropomodulin-1 isoform X2 [KO:K10370]
100049724  zyx.S; zyxin [KO:K06273]
108695689  zyxin-like [KO:K06273]
446852  fhl1.L; four and a half LIM domains protein 1 isoform X1 [KO:K14365]
447182  fhl1.S; four and a half LIM domains 1 S homeolog [KO:K14365]
108709713  fhl2.S; four and a half LIM domains protein 2 [KO:K14380]
108708415  fhl2.L; four and a half LIM domains protein 2 [KO:K14380]
108708232  fhl3.L; four and a half LIM domains protein 3 [KO:K24414]
444152  fhl3.S; four and a half LIM domains protein 3 [KO:K24414]
108711149  leiomodin-2 [KO:K22030]
108709498  lmod1.S; leiomodin-1 [KO:K22030]
108714721  leiomodin-3 [KO:K22030]
108715918  leiomodin-3 [KO:K22030]
108707488  lmod1.L; leiomodin-1 isoform X2 [KO:K22030]
108713095  leiomodin-2 [KO:K22030]
734696  ankrd1.L; ankyrin repeat domain-containing protein 1 [KO:K21433]
108697930  ankrd1.S; ankyrin repeat domain-containing protein 1 [KO:K21433]
447042  ankrd2.S; ankyrin repeat domain 2 (stretch responsive muscle) S homeolog [KO:K21434]
380293  ankrd2.L; ankyrin repeat domain 2 (stretch responsive muscle) L homeolog [KO:K21434]
108701328  formin-like protein 2 isoform X1 [KO:K23957]
108702182  fmnl1.S; formin-like protein 1 [KO:K23957]
108702264  formin-like protein 2 isoform X1 [KO:K23957]
108707545  LOW QUALITY PROTEIN: formin-like protein 3 [KO:K23957]
108709808  formin-like protein 3 isoform X1 [KO:K23957]
444576  fmnl1.L; formin like 1 L homeolog [KO:K23957]
495032  inf2.L; inverted formin-2-like isoform X1 [KO:K23958]
414513  inf2.S; inverted formin-2 [KO:K23958]
108717662  daam2.S; disheveled-associated activator of morphogenesis 2 [KO:K04512]
443650  daam1.S; disheveled-associated activator of morphogenesis 1-A-like isoform X2 [KO:K04512]
108698833  daam1.L; disheveled-associated activator of morphogenesis 1-A isoform X1 [KO:K04512]
108716513  disheveled-associated activator of morphogenesis 2 [KO:K04512]
108713303  diaph1.S; protein diaphanous homolog 1 [KO:K05740]
108710882  diaph1.L; protein diaphanous homolog 1 isoform X3 [KO:K05740]
108698412  diaph2.L; protein diaphanous homolog 2 isoform X1 [KO:K05741]
108708510  diaph3.L; protein diaphanous homolog 3 isoform X1 [KO:K05745]
108716740  fmn2.L; formin-2 [KO:K02184]
108695595  myom1.S; myomesin-1 isoform X2 [KO:K24495]
108719208  myom1.L; myomesin-1 isoform X1 [KO:K24495]
108716934  myom2.L; myomesin-2 isoform X1 [KO:K24495]
108705440  myom3.L; myomesin-3 [KO:K24495]
108717439  M-protein, striated muscle [KO:K24495]
379079  eno1.L; enolase 1 a [KO:K01689] [EC:4.2.1.11]
380038  eno3.L; enolase 3 [KO:K01689] [EC:4.2.1.11]
380298  eno1.S; alpha-enolase [KO:K01689] [EC:4.2.1.11]
108706710  ankyrin-2 isoform X35 [KO:K09255]
108710308  ankyrin-2 isoform X1 [KO:K09255]
108700198  ckm.S; creatine kinase M-type [KO:K27382] [EC:2.7.3.2]
379765  ckm.L; muscle creatine kinase [KO:K27382] [EC:2.7.3.2]
432166  trim54.S; tripartite motif containing 54 S homeolog [KO:K10653]
108716295  trim54.L; tripartite motif-containing protein 54 [KO:K10653]
100036929  trim55.L; uncharacterized protein LOC100036929 [KO:K10654]
108695323  trim55.S; tripartite motif-containing protein 55 [KO:K10654]
100036938  trim63.L; uncharacterized protein LOC100036938 [KO:K10655] [EC:2.3.2.27]
446518  trim63.S; tripartite motif containing 63 S homeolog [KO:K10655] [EC:2.3.2.27]
108713730  ampd3.L; AMP deaminase 3 isoform X1 [KO:K01490] [EC:3.5.4.6]
108709466  ampd2.S; AMP deaminase 2 isoform X4 [KO:K01490] [EC:3.5.4.6]
108715290  ampd3.S; AMP deaminase 3 isoform X1 [KO:K01490] [EC:3.5.4.6]
108709397  ampd1.S; AMP deaminase 1 isoform X1 [KO:K01490] [EC:3.5.4.6]
108708064  ampd1.L; AMP deaminase 1 [KO:K01490] [EC:3.5.4.6]
108719653  obscurin isoform X1 [KO:K17531] [EC:2.7.11.1]
108718692  obscurin [KO:K17531] [EC:2.7.11.1]
100125665  capn3.L; calpain 3 L homeolog [KO:K08573] [EC:3.4.22.54]
108700461  calpain-3 isoform X1 [KO:K08573] [EC:3.4.22.54]
108695482  plec.S; plectin isoform X3 [KO:K10388]
108695484  plectin-like isoform X1 [KO:K10388]
108698736  syne3.L; nesprin-3 isoform X1 [KO:K21761]
108699810  syne3.S; nesprin-3 isoform X1 [KO:K21761]
399433  syne1.L; nesprin-1 isoform X3 [KO:K19326]
108699756  syne2.2.S; nesprin-2 isoform X1 [KO:K19346]
108698815  nesprin-2-like isoform X1 [KO:K19346]
108715771  sun2.S; SUN domain-containing protein 2 isoform X1 [KO:K19347]
108703140  sun1.S; SUN domain-containing protein 1 isoform X3 [KO:K19347]
100380982  sun2.L; SUN domain-containing protein 2 isoform X1 [KO:K19347]
733164  sun1.L; SUN domain-containing protein 1 isoform X1 [KO:K19347]
108714654  transmembrane protein 43 isoform X1 [KO:K27488]
733232  emd.S; emerin S homeolog [KO:K12569]
733233  emd.L; emerin L homeolog [KO:K12569]
108716485  lbr.L; delta(14)-sterol reductase LBR [KO:K19532] [EC:1.3.1.70]
378609  lbr.S; lamin B receptor S homeolog [KO:K19532] [EC:1.3.1.70]
373673  lmna.L; lamin-A [KO:K12641]
108700617  LOW QUALITY PROTEIN: lamin-A-like [KO:K12641]
379745  lmnb1.L; lamin B1 L homeolog [KO:K07611]
394291  lmnb2.S; lamin B2 S homeolog [KO:K07611]
397910  lmnb3.L; lamin-L(III) [KO:K07611]
397911  lmnb1.S; lamin-L(I) [KO:K07611]
397912  lmnb2.L; lamin-L(II) [KO:K07611]
734958  lmnb3.S; lamin-L(III) [KO:K07611]
Reference
  Authors
Clark KA, McElhinny AS, Beckerle MC, Gregorio CC
  Title
Striated muscle cytoarchitecture: an intricate web of form and function.
  Journal
Annu Rev Cell Dev Biol 18:637-706 (2002)
DOI:10.1146/annurev.cellbio.18.012502.105840
Reference
  Authors
Mukund K, Subramaniam S
  Title
Skeletal muscle: A review of molecular structure and function, in health and disease.
  Journal
Wiley Interdiscip Rev Syst Biol Med 12:e1462 (2020)
DOI:10.1002/wsbm.1462
Reference
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Stroud MJ, Banerjee I, Veevers J, Chen J
  Title
Linker of nucleoskeleton and cytoskeleton complex proteins in cardiac structure, function, and disease.
  Journal
Circ Res 114:538-48 (2014)
DOI:10.1161/CIRCRESAHA.114.301236
Reference
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Henderson CA, Gomez CG, Novak SM, Mi-Mi L, Gregorio CC
  Title
Overview of the Muscle Cytoskeleton.
  Journal
Compr Physiol 7:891-944 (2017)
DOI:10.1002/cphy.c160033
Reference
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Csapo R, Gumpenberger M, Wessner B
  Title
Skeletal Muscle Extracellular Matrix - What Do We Know About Its Composition, Regulation, and Physiological Roles? A Narrative Review.
  Journal
Front Physiol 11:253 (2020)
DOI:10.3389/fphys.2020.00253
Reference
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Pinch M, Guth R, Samanta MP, Chaidez A, Unguez GA
  Title
The myogenic electric organ of Sternopygus macrurus: a non-contractile tissue with a skeletal muscle transcriptome.
  Journal
PeerJ 4:e1828 (2016)
DOI:10.7717/peerj.1828
Reference
  Authors
Sequeira V, Nijenkamp LL, Regan JA, van der Velden J
  Title
The physiological role of cardiac cytoskeleton and its alterations in heart failure.
  Journal
Biochim Biophys Acta 1838:700-22 (2014)
DOI:10.1016/j.bbamem.2013.07.011
Reference
  Authors
Zhang B, Powers JD, McCulloch AD, Chi NC
  Title
Nuclear mechanosignaling in striated muscle diseases.
  Journal
Front Physiol 14:1126111 (2023)
DOI:10.3389/fphys.2023.1126111
Reference
  Authors
Al-Amoudi A, Castano-Diez D, Devos DP, Russell RB, Johnson GT, Frangakis AS
  Title
The three-dimensional molecular structure of the desmosomal plaque.
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Proc Natl Acad Sci U S A 108:6480-5 (2011)
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Reference
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Sikora M, Ermel UH, Seybold A, Kunz M, Calloni G, Reitz J, Vabulas RM, Hummer G, Frangakis AS
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Desmosome architecture derived from molecular dynamics simulations and cryo-electron tomography.
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Proc Natl Acad Sci U S A 117:27132-27140 (2020)
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Reference
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Xu XP, Kim E, Swift M, Smith JW, Volkmann N, Hanein D
  Title
Three-Dimensional Structures of Full-Length, Membrane-Embedded Human alpha(IIb)beta(3) Integrin Complexes.
  Journal
Biophys J 110:798-809 (2016)
DOI:10.1016/j.bpj.2016.01.016
Reference
  Authors
Wang W, Shi Z, Jiao S, Chen C, Wang H, Liu G, Wang Q, Zhao Y, Greene MI, Zhou Z
  Title
Structural insights into SUN-KASH complexes across the nuclear envelope.
  Journal
Cell Res 22:1440-52 (2012)
DOI:10.1038/cr.2012.126
Reference
  Authors
Sosa BA, Kutay U, Schwartz TU
  Title
Structural insights into LINC complexes.
  Journal
Curr Opin Struct Biol 23:285-91 (2013)
DOI:10.1016/j.sbi.2013.03.005
Reference
  Authors
Cruz VE, Esra Demircioglu F, Schwartz TU
  Title
Structural Analysis of Different LINC Complexes Reveals Distinct Binding Modes.
  Journal
J Mol Biol 432:6028-6041 (2020)
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Reference
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Schuler SC, Liu Y, Dumontier S, Grandbois M, Le Moal E, Cornelison D, Bentzinger CF
  Title
Extracellular matrix: Brick and mortar in the skeletal muscle stem cell niche.
  Journal
Front Cell Dev Biol 10:1056523 (2022)
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Reference
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Brull A, Morales Rodriguez B, Bonne G, Muchir A, Bertrand AT
  Title
The Pathogenesis and Therapies of Striated Muscle Laminopathies.
  Journal
Front Physiol 9:1533 (2018)
DOI:10.3389/fphys.2018.01533
Reference
  Authors
Storey EC, Fuller HR
  Title
Genotype-Phenotype Correlations in Human Diseases Caused by Mutations of LINC Complex-Associated Genes: A Systematic Review and Meta-Summary.
  Journal
Cells 11:cells11244065 (2022)
DOI:10.3390/cells11244065
Related
pathway
xla04512  ECM-receptor interaction
xla04814  Motor proteins
KO pathway
ko04820   
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