KEGG   PATHWAY: spen03040
Entry
spen03040                   Pathway                                
Name
Spliceosome - Solanum pennellii
Description
After transcription, eukaryotic mRNA precursors contain protein-coding exons and noncoding introns. In the following splicing, introns are excised and exons are joined by a macromolecular complex, the spliceosome. The standard spliceosome is made up of five small nuclear ribonucleoproteins (snRNPs), U1, U2, U4, U5, and U6 snRNPs, and several spliceosome-associated proteins (SAPs). Spliceosomes are not a simple stable complex, but a dynamic family of particles that assemble on the mRNA precursor and help fold it into a conformation that allows transesterification to proceed. Various spliceosome forms (e.g. A-, B- and C-complexes) have been identified.
Class
Genetic Information Processing; Transcription
Pathway map
spen03040  Spliceosome
spen03040

Other DBs
GO: 0005681
Organism
Solanum pennellii [GN:spen]
Gene
114077027  U1 spliceosomal RNA [KO:K14276]
114076594  U1 spliceosomal RNA [KO:K14276]
114074969  U1 spliceosomal RNA [KO:K14276]
114074965  U1 spliceosomal RNA [KO:K14276]
114075743  U1 spliceosomal RNA [KO:K14276]
114074556  U1 spliceosomal RNA [KO:K14276]
114077706  U1 spliceosomal RNA [KO:K14276]
114077382  U1 spliceosomal RNA [KO:K14276]
114075742  U1 spliceosomal RNA [KO:K14276]
114075741  U1 spliceosomal RNA [KO:K14276]
114074545  U1 spliceosomal RNA [KO:K14276]
114076204  U2 spliceosomal RNA [KO:K14277]
114077722  U2 spliceosomal RNA [KO:K14277]
114078517  U2 spliceosomal RNA [KO:K14277]
114076201  U2 spliceosomal RNA [KO:K14277]
114076199  U2 spliceosomal RNA [KO:K14277]
114078156  U2 spliceosomal RNA [KO:K14277]
114076206  U2 spliceosomal RNA [KO:K14277]
114076191  U2 spliceosomal RNA [KO:K14277]
114078160  U2 spliceosomal RNA [KO:K14277]
114076597  U2 spliceosomal RNA [KO:K14277]
114076211  U4 spliceosomal RNA [KO:K14278]
114074540  U4 spliceosomal RNA [KO:K14278]
114077728  U4 spliceosomal RNA [KO:K14278]
114076212  U4 spliceosomal RNA [KO:K14278]
114076603  U4 spliceosomal RNA [KO:K14278]
114077019  U5 spliceosomal RNA [KO:K14279]
114075768  U5 spliceosomal RNA [KO:K14279]
114077729  U5 spliceosomal RNA [KO:K14279]
114075766  U5 spliceosomal RNA [KO:K14279]
114074546  U6 spliceosomal RNA [KO:K14280]
114078176  U6 spliceosomal RNA [KO:K14280]
114078491  U6 spliceosomal RNA [KO:K14280]
114078490  U6 spliceosomal RNA [KO:K14280]
114075436  U6 spliceosomal RNA [KO:K14280]
107007206  DEAD-box ATP-dependent RNA helicase 42 [KO:K12811] [EC:5.6.2.7]
107028586  DEAD-box ATP-dependent RNA helicase 56 isoform X1 [KO:K12812] [EC:5.6.2.7]
107023382  DEAD-box ATP-dependent RNA helicase 56-like [KO:K12812] [EC:5.6.2.7]
107006955  pre-mRNA-splicing factor ATP-dependent RNA helicase DEAH1-like [KO:K12813] [EC:5.6.2.6]
107029928  pre-mRNA-splicing factor ATP-dependent RNA helicase DEAH1-like [KO:K12813] [EC:5.6.2.6]
107014630  pre-mRNA-splicing factor ATP-dependent RNA helicase DEAH1-like isoform X1 [KO:K12813] [EC:5.6.2.6]
107002152  pre-mRNA-splicing factor ATP-dependent RNA helicase DEAH7 [KO:K12815] [EC:5.6.2.6]
107007690  pre-mRNA-splicing factor ATP-dependent RNA helicase DEAH7-like isoform X1 [KO:K12815] [EC:5.6.2.6]
107011665  pre-mRNA-processing factor 17 isoform X1 [KO:K12816]
107031563  pre-mRNA-splicing factor 18 [KO:K12817]
107017803  ATP-dependent RNA helicase DEAH12, chloroplastic-like [KO:K12818] [EC:5.6.2.6]
107029326  pre-mRNA-splicing factor ATP-dependent RNA helicase DEAH10 [KO:K12818] [EC:5.6.2.6]
107026163  probable pre-mRNA-splicing factor ATP-dependent RNA helicase DEAH5 [KO:K12818] [EC:5.6.2.6]
107005125  probable pre-mRNA-splicing factor ATP-dependent RNA helicase DEAH5 [KO:K12818] [EC:5.6.2.6]
107020942  probable pre-mRNA-splicing factor ATP-dependent RNA helicase DEAH4 [KO:K12818] [EC:5.6.2.6]
107004738  ATP-dependent RNA helicase DEAH11, chloroplastic-like [KO:K12818] [EC:5.6.2.6]
107021184  pre-mRNA-splicing factor SLU7-like [KO:K12819]
107031352  pre-mRNA-splicing factor SLU7-like [KO:K12819]
107005106  probable pre-mRNA-splicing factor ATP-dependent RNA helicase DEAH2 [KO:K12820] [EC:5.6.2.6]
107008587  small nuclear ribonucleoprotein-associated protein B'-like [KO:K11086]
107023438  small nuclear ribonucleoprotein SmD1b [KO:K11087]
107029464  small nuclear ribonucleoprotein SmD1b [KO:K11087]
107029209  small nuclear ribonucleoprotein Sm D2 [KO:K11096]
107009065  small nuclear ribonucleoprotein SmD3b-like [KO:K11088]
107012446  small nuclear ribonucleoprotein SmD3b-like [KO:K11088]
107009220  small nuclear ribonucleoprotein SmD3b-like [KO:K11088]
107021497  small nuclear ribonucleoprotein E-like [KO:K11097]
107012380  small nuclear ribonucleoprotein E-like [KO:K11097]
107032133  probable small nuclear ribonucleoprotein F [KO:K11098]
107020294  probable small nuclear ribonucleoprotein G [KO:K11099]
107002917  probable small nuclear ribonucleoprotein G [KO:K11099]
107011027  U1 small nuclear ribonucleoprotein 70 kDa isoform X1 [KO:K11093]
107029220  U1 small nuclear ribonucleoprotein A [KO:K11091]
107010136  U1 small nuclear ribonucleoprotein C-like [KO:K11095]
107022059  U1 small nuclear ribonucleoprotein C-like [KO:K11095]
107005049  pre-mRNA-processing protein 40A-like isoform X1 [KO:K12821]
107025892  pre-mRNA-processing protein 40A isoform X1 [KO:K12821]
107020281  RNA-binding protein 25 isoform X1 [KO:K12822]
107007398  DEAD-box ATP-dependent RNA helicase 20 [KO:K12823] [EC:5.6.2.7]
107014623  DEAD-box ATP-dependent RNA helicase 20 [KO:K12823] [EC:5.6.2.7]
107007111  ATP-dependent RNA helicase-like protein DB10 [KO:K12823] [EC:5.6.2.7]
107011069  ATP-dependent RNA helicase-like protein DB10 [KO:K12823] [EC:5.6.2.7]
107004850  DEAD-box ATP-dependent RNA helicase 46-like [KO:K12823] [EC:5.6.2.7]
107031392  DEAD-box ATP-dependent RNA helicase 20-like [KO:K12823] [EC:5.6.2.7]
107017715  pre-mRNA-processing protein 40C isoform X1 [KO:K12824]
107023266  transcription initiation factor TFIID subunit 15b [KO:K13098]
107014342  U2 small nuclear ribonucleoprotein A' [KO:K11092]
107021034  U2 small nuclear ribonucleoprotein B'' [KO:K11094]
107011251  probable splicing factor 3A subunit 1 [KO:K12825]
107017700  probable splicing factor 3A subunit 1 [KO:K12825]
107031064  splicing factor 3A subunit 2 [KO:K12826]
107014391  splicing factor SF3a60 homolog [KO:K12827]
107002044  splicing factor 3B subunit 1 [KO:K12828]
107010968  splicing factor 3B subunit 2 [KO:K12829]
107015513  splicing factor 3B subunit 2-like [KO:K12829]
107017738  spliceosome-associated protein 130 A [KO:K12830]
107002397  pre-mRNA-splicing factor prp12 [KO:K12830]
107014939  splicing factor 3B subunit 4 [KO:K12831]
107005018  RNA-binding protein SGN1 isoform X1 [KO:K12831]
107015591  uncharacterized protein At4g14342 isoform X1 [KO:K12832]
107027205  uncharacterized protein At4g14342-like [KO:K12832]
107008653  splicing factor 3B subunit 6-like protein [KO:K12833]
107005527  PHD finger-like domain-containing protein 5B [KO:K12834]
107007783  DEAD-box ATP-dependent RNA helicase 24 [KO:K12835] [EC:5.6.2.7]
107004803  splicing factor U2af small subunit B [KO:K12836]
107002305  splicing factor U2af small subunit B-like [KO:K12836]
107011096  splicing factor U2af large subunit B isoform X1 [KO:K12837]
107031347  uncharacterized protein LOC107031347 [KO:K12837]
107007245  splicing factor U2af large subunit A-like isoform X1 [KO:K12837]
107011503  splicing factor U2af large subunit A isoform X1 [KO:K12837]
107008362  survival of motor neuron-related-splicing factor 30 isoform X1 [KO:K12839]
107010911  DNA-damage-repair/toleration protein DRT111, chloroplastic [KO:K12840]
107014556  LOW QUALITY PROTEIN: protein RRC1-like [KO:K12842]
107021391  sm-like protein LSM2 [KO:K12621]
107031362  sm-like protein LSM2 [KO:K12621]
107004446  sm-like protein LSM3A [KO:K12622]
107008101  probable U6 snRNA-associated Sm-like protein LSm4 [KO:K12623]
107029578  probable U6 snRNA-associated Sm-like protein LSm4 [KO:K12623]
107029605  sm-like protein LSM5 [KO:K12624]
107032205  sm-like protein LSM36B [KO:K12625]
107029358  sm-like protein LSM7 [KO:K12626]
107021163  sm-like protein LSM8 [KO:K12627]
107018979  protein RDM16-like isoform X1 [KO:K12843]
107023328  protein RDM16-like isoform X1 [KO:K12843]
107017856  U4/U6 small nuclear ribonucleoprotein PRP4-like protein [KO:K12662]
107007870  peptidyl-prolyl cis-trans isomerase CYP22 [KO:K09567] [EC:5.2.1.8]
107028933  U4/U6 small nuclear ribonucleoprotein Prp31 homolog [KO:K12844]
107025661  U4/U6 small nuclear ribonucleoprotein Prp31 homolog isoform X2 [KO:K12844]
107029401  NHP2-like protein 1 [KO:K12845]
107029539  NHP2-like protein 1 [KO:K12845]
107026465  U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein [KO:K12846]
107011965  U4/U6.U5 tri-snRNP-associated protein 2-like isoform X1 [KO:K12847]
107004369  SART-1 family protein DOT2 [KO:K11984]
107001373  zinc finger matrin-type protein 2 [KO:K12848]
107008253  pre-mRNA-splicing factor 38 isoform X1 [KO:K12849]
107017867  pre-mRNA splicing factor SR-like 1 isoform X1 [KO:K12850]
107025924  110 kDa U5 small nuclear ribonucleoprotein component CLO [KO:K12852]
107022999  DExH-box ATP-dependent RNA helicase DExH12-like [KO:K12854] [EC:5.6.2.6]
107026062  protein STABILIZED1 [KO:K12855]
107025352  pre-mRNA-processing-splicing factor 8A [KO:K12856]
107015323  U5 small nuclear ribonucleoprotein 40 kDa protein isoform X1 [KO:K12857]
107009542  DEAD-box ATP-dependent RNA helicase 21-like [KO:K12858] [EC:5.6.2.7]
107010997  DEAD-box ATP-dependent RNA helicase 21 [KO:K12858] [EC:5.6.2.7]
107018165  thioredoxin-like protein YLS8 isoform X2 [KO:K12859]
107011595  thioredoxin-like protein YLS8 isoform X2 [KO:K12859]
107031322  pre-mRNA-processing factor 19 [KO:K10599] [EC:2.3.2.27]
107017708  cell division cycle 5-like protein [KO:K12860]
107008122  protein pleiotropic regulatory locus 1-like [KO:K12862]
107024195  protein CWC15 homolog isoform X2 [KO:K12863]
107031880  protein CWC15 homolog [KO:K12863]
107011719  beta-catenin-like protein 1 [KO:K12864]
107001250  stromal 70 kDa heat shock-related protein, chloroplastic [KO:K03283]
107002027  heat shock cognate 70 kDa protein 2 [KO:K03283]
107024641  heat shock 70 kDa protein-like [KO:K03283]
107021810  probable mediator of RNA polymerase II transcription subunit 37c [KO:K03283]
107023850  heat shock cognate 70 kDa protein 1 [KO:K03283]
107005034  heat shock 70 kDa protein 7, chloroplastic-like [KO:K03283]
107004415  heat shock cognate 70 kDa protein 2-like [KO:K03283]
107004938  heat shock cognate 70 kDa protein [KO:K03283]
107015820  heat shock cognate 70 kDa protein 2-like [KO:K03283]
107014574  heat shock 70 kDa protein 5 [KO:K03283]
107030866  heat shock cognate 70 kDa protein 2-like [KO:K03283]
107002929  uncharacterized protein LOC107002929 [KO:K12865]
107007102  SNW/SKI-interacting protein A [KO:K06063]
107007786  pre-mRNA-splicing factor SYF1 [KO:K12867]
107002731  pre-mRNA-splicing factor syf2 [KO:K12868]
107025646  pre-mRNA-splicing factor syf2-like [KO:K12868]
107027792  pre-mRNA-splicing factor syf2-like [KO:K12868]
107013046  crooked neck-like protein 1 [KO:K12869]
107013047  crooked neck-like protein 1 [KO:K12869]
107007401  crooked neck-like protein 1 [KO:K12869]
107012936  crooked neck-like protein 1 [KO:K12869]
107031823  crooked neck-like protein 1 [KO:K12869]
107018613  pre-mRNA-splicing factor ISY1 homolog isoform X2 [KO:K12870]
107029475  peptidyl-prolyl cis-trans isomerase CYP18-2 isoform X1 [KO:K12733] [EC:5.2.1.8]
107021545  coiled-coil domain-containing protein 12 [KO:K12871]
107018066  zinc finger CCCH domain-containing protein 49-like [KO:K12872]
107002218  zinc finger CCCH domain-containing protein 49-like [KO:K12872]
107031612  protein BUD31 homolog 2 [KO:K12873]
107003262  protein BUD31 homolog 1-like [KO:K12873]
107028542  RNA helicase aquarius [KO:K12874]
107017631  apoptotic chromatin condensation inducer in the nucleus [KO:K12875]
107004776  eukaryotic initiation factor 4A-3 [KO:K13025] [EC:5.6.2.7]
107023796  RNA-binding protein Y14A [KO:K12876]
107012135  protein mago nashi homolog [KO:K12877]
107007975  THO complex subunit 1 isoform X2 [KO:K12878]
107020310  THO complex subunit 2 isoform X1 [KO:K12879]
107026158  THO complex subunit 3 [KO:K12880]
107017760  THO complex subunit 4D [KO:K12881]
107002742  THO complex subunit 4A-like [KO:K12881]
107004646  THO complex subunit 4D [KO:K12881]
107005022  THO complex subunit 4A [KO:K12881]
107002467  nuclear cap-binding protein subunit 1 [KO:K12882]
107011754  nuclear cap-binding protein subunit 2 [KO:K12883]
107011524  heterogeneous nuclear ribonucleoprotein 1 [KO:K12741]
107010823  glycine-rich RNA-binding protein 4, mitochondrial-like [KO:K12741]
107002291  UBP1-associated protein 2A-like [KO:K12741]
107002527  glycine-rich RNA-binding protein 4, mitochondrial-like [KO:K12741]
107025728  heterogeneous nuclear ribonucleoprotein 1 [KO:K12741]
107015359  heterogeneous nuclear ribonucleoprotein 1-like isoform X1 [KO:K12741]
107017979  UBP1-associated protein 2B-like [KO:K12741]
107009702  glycine-rich RNA-binding protein 3, mitochondrial-like [KO:K12741]
107011047  UBP1-associated protein 2C-like [KO:K12741]
107022929  heterogeneous nuclear ribonucleoprotein 1-like [KO:K12741]
107002630  UBP1-associated protein 2B-like [KO:K12741]
107007283  UBP1-associated protein 2C-like [KO:K12741]
107015372  serine/arginine-rich splicing factor SR30 isoform X1 [KO:K12890]
107014841  serine/arginine-rich splicing factor SR34A isoform X1 [KO:K12890]
107031508  serine/arginine-rich-splicing factor SR34-like [KO:K12890]
107023233  serine/arginine-rich splicing factor SR34B-like [KO:K12890]
107017986  serine/arginine-rich splicing factor SC35-like isoform X1 [KO:K12891]
107007819  serine/arginine-rich splicing factor SC35 isoform X2 [KO:K12891]
107019640  serine/arginine-rich splicing factor RS41-like isoform X1 [KO:K12893]
107014836  serine/arginine-rich splicing factor RS31-like isoform X1 [KO:K12893]
107008395  serine/arginine-rich splicing factor RS31-like isoform X1 [KO:K12893]
107004592  serine/arginine-rich splicing factor RS31-like isoform X1 [KO:K12893]
107002607  serine/arginine-rich splicing factor RS31-like isoform X1 [KO:K12893]
107020617  serine/arginine-rich splicing factor RS2Z32-like isoform X1 [KO:K12896]
107031617  serine/arginine-rich splicing factor RS2Z33-like isoform X1 [KO:K12896]
107028665  serine/arginine-rich splicing factor RSZ22-like isoform X2 [KO:K12896]
107026647  serine/arginine-rich splicing factor RSZ22A-like isoform X1 [KO:K12896]
107009955  serine/arginine-rich splicing factor SR45a [KO:K12897]
107011868  serine/arginine-rich splicing factor SR45a [KO:K12897]
107007028  serine/arginine-rich SC35-like splicing factor SCL28 [KO:K12900]
107006520  serine/arginine-rich SC35-like splicing factor SCL33 [KO:K12900]
Reference
PMID:19239890
  Authors
Wahl MC, Will CL, Luhrmann R
  Title
The spliceosome: design principles of a dynamic RNP machine.
  Journal
Cell 136:701-18 (2009)
DOI:10.1016/j.cell.2009.02.009
Reference
PMID:10978320
  Authors
Morris DP, Greenleaf AL
  Title
The splicing factor, Prp40, binds the phosphorylated carboxyl-terminal domain of RNA polymerase II.
  Journal
J Biol Chem 275:39935-43 (2000)
DOI:10.1074/jbc.M004118200
Reference
PMID:17537823
  Authors
Chen YI, Moore RE, Ge HY, Young MK, Lee TD, Stevens SW
  Title
Proteomic analysis of in vivo-assembled pre-mRNA splicing complexes expands the catalog of participating factors.
  Journal
Nucleic Acids Res 35:3928-44 (2007)
DOI:10.1093/nar/gkm347
Reference
PMID:19733268
  Authors
Ritchie DB, Schellenberg MJ, MacMillan AM
  Title
Spliceosome structure: piece by piece.
  Journal
Biochim Biophys Acta 1789:624-33 (2009)
DOI:10.1016/j.bbagrm.2009.08.010
KO pathway
ko03040   
LinkDB

DBGET integrated database retrieval system