KEGG   PATHWAY: anu05169
Entry
anu05169                    Pathway                                
Name
Epstein-Barr virus infection - Arvicanthis niloticus (African grass rat)
Description
Epstein-Barr virus (EBV) is a gamma-herpes virus that widely infects human populations predominantly at an early age but remains mostly asymptomatic. EBV has been linked to a wide spectrum of human malignancies, including nasopharyngeal carcinoma and other hematologic cancers, like Hodgkin's lymphoma, Burkitt's lymphoma (BL), B-cell immunoblastic lymphoma in HIV patients, and posttransplant-associated lymphoproliferative diseases.  EBV has the unique ability to establish life-long latent infection in primary human B lymphocytes. During latent infection, EBV expresses a small subset of genes, including 6 nuclear antigens (EBNA-1, -2, -3A, -3B, -3C, and -LP), 3 latent membrane proteins (LMP-1, -2A, and -2B), 2 small noncoding RNAs (EBER-1 and 2). On the basis of these latent gene expression, three different latency patterns associated with the types of cancers are recognized.
Class
Human Diseases; Infectious disease: viral
Pathway map
anu05169  Epstein-Barr virus infection
anu05169

Organism
Arvicanthis niloticus (African grass rat) [GN:anu]
Gene
117716040  LOW QUALITY PROTEIN: complement receptor type 2-like [KO:K04012]
117722002  Cd19; B-lymphocyte antigen CD19 isoform X1 [KO:K06465]
117724116  class II histocompatibility antigen, M alpha chain [KO:K06752]
117724153  rano class II histocompatibility antigen, D-1 beta chain-like isoform X1 [KO:K06752]
117724155  H-2 class II histocompatibility antigen, I-E beta chain [KO:K06752]
117724265  HLA class II histocompatibility antigen, DP beta 1 chain-like [KO:K06752]
117724266  rano class II histocompatibility antigen, B-1 beta chain-like [KO:K06752]
117724267  H-2 class II histocompatibility antigen, E-U alpha chain [KO:K06752]
117724439  H-2 class II histocompatibility antigen, E-U alpha chain-like [KO:K06752]
117724491  HLA class II histocompatibility antigen, DO alpha chain [KO:K06752]
117724498  RLA class II histocompatibility antigen, DP alpha-1 chain [KO:K06752]
117724568  H-2 class II histocompatibility antigen, I-E alpha chain-like [KO:K06752]
117724845  class II histocompatibility antigen, M beta 1 chain [KO:K06752]
117724929  HLA class II histocompatibility antigen, DO beta chain [KO:K06752]
117724945  H-2 class II histocompatibility antigen, A beta chain [KO:K06752]
117724946  H-2 class II histocompatibility antigen, A-R alpha chain-like [KO:K06752]
117707783  Tlr2; toll-like receptor 2 [KO:K10159]
117693388  Myd88; myeloid differentiation primary response protein MyD88 [KO:K04729]
117718426  Irak4; interleukin-1 receptor-associated kinase 4 [KO:K04733] [EC:2.7.11.1]
117694459  Irak1; interleukin-1 receptor-associated kinase 1 isoform X1 [KO:K04730] [EC:2.7.11.1]
117703656  Traf6; TNF receptor-associated factor 6 [KO:K03175] [EC:2.3.2.27]
117719404  Tab1; TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 [KO:K04403]
117700141  Tab2; TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 [KO:K04404]
117698575  Map3k7; mitogen-activated protein kinase kinase kinase 7 isoform X1 [KO:K04427] [EC:2.7.11.25]
117701914  inhibitor of nuclear factor kappa-B kinase subunit alpha-like [KO:K04467] [EC:2.7.11.10]
117712831  Chuk; inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1 [KO:K04467] [EC:2.7.11.10]
117721547  Ikbkb; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1 [KO:K07209] [EC:2.7.11.10]
117695513  Ikbkg; NF-kappa-B essential modulator isoform X1 [KO:K07210]
117717335  Nfkbia; NF-kappa-B inhibitor alpha [KO:K04734]
117707042  Nfkb1; nuclear factor NF-kappa-B p105 subunit isoform X1 [KO:K02580]
117722582  Rela; transcription factor p65 [KO:K04735]
117724681  Tnf; tumor necrosis factor isoform X1 [KO:K03156]
117720807  Il6; interleukin-6 [KO:K05405]
117709414  Ddx58; antiviral innate immune response receptor RIG-I [KO:K12646] [EC:5.6.2.6]
117704174  Mavs; mitochondrial antiviral-signaling protein isoform X1 [KO:K12648]
117697234  Traf3; TNF receptor-associated factor 3 [KO:K03174]
117696401  Tbk1; serine/threonine-protein kinase TBK1 [KO:K05410] [EC:2.7.11.10]
117716315  Ikbke; inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform X1 [KO:K07211] [EC:2.7.11.10]
117713181  Irf7; interferon regulatory factor 7 isoform X1 [KO:K09447]
117708685  Irf3; interferon regulatory factor 3 isoform X1 [KO:K05411]
117708733  interferon alpha-12-like [KO:K05414]
117709002  interferon alpha-12-like [KO:K05414]
117709023  interferon alpha-9 [KO:K05414]
117709053  interferon alpha-1-like [KO:K05414]
117709056  interferon alpha-1-like isoform X1 [KO:K05414]
117709071  interferon alpha-7-like [KO:K05414]
117709072  interferon alpha-12-like [KO:K05414]
117709075  interferon alpha-12-like [KO:K05414]
117709078  interferon alpha-12-like [KO:K05414]
117709079  interferon alpha-1 [KO:K05414]
117709081  interferon alpha-12-like [KO:K05414]
117709083  interferon alpha-12-like [KO:K05414]
117709084  interferon alpha-7 [KO:K05414]
117709085  interferon alpha-12-like [KO:K05414]
117709086  interferon alpha-7-like [KO:K05414]
117709102  interferon alpha-1-like [KO:K05414]
117709633  Ifnb1; interferon beta [KO:K05415]
117718162  Ifnar1; interferon alpha/beta receptor 1 isoform X1 [KO:K05130]
117718170  Ifnar2; interferon alpha/beta receptor 2 [KO:K05131]
117709127  Jak1; tyrosine-protein kinase JAK1 [KO:K11217] [EC:2.7.10.2]
117713684  Tyk2; non-receptor tyrosine-protein kinase TYK2 [KO:K11219] [EC:2.7.10.2]
117705244  Stat1; signal transducer and activator of transcription 1-alpha/beta [KO:K11220]
117696619  Stat2; signal transducer and activator of transcription 2 isoform X1 [KO:K11221]
117706177  Irf9; interferon regulatory factor 9 [KO:K04693]
117717229  Eif2ak2; interferon-induced, double-stranded RNA-activated protein kinase [KO:K16195] [EC:2.7.11.1]
117701826  LOW QUALITY PROTEIN: interferon-induced, double-stranded RNA-activated protein kinase-like [KO:K16195] [EC:2.7.11.1]
117697668  Oas3; 2'-5'-oligoadenylate synthase 3 isoform X1 [KO:K14216] [EC:2.7.7.84]
117697784  inactive 2'-5'-oligoadenylate synthase 1B-like isoform X1 [KO:K14216] [EC:2.7.7.84]
117697786  2'-5'-oligoadenylate synthase 1A [KO:K14216] [EC:2.7.7.84]
117697788  2'-5'-oligoadenylate synthase 1A-like [KO:K14216] [EC:2.7.7.84]
117697969  2'-5'-oligoadenylate synthase 1A-like [KO:K14216] [EC:2.7.7.84]
117698180  Oas2; LOW QUALITY PROTEIN: 2'-5'-oligoadenylate synthase 2 [KO:K14216] [EC:2.7.7.84]
117699623  Cxcl10; C-X-C motif chemokine 10 [KO:K12671]
117709183  Isg15; ubiquitin-like protein ISG15 [KO:K12159]
117700780  Fas; tumor necrosis factor receptor superfamily member 6 isoform X1 [KO:K04390]
117710030  Fadd; FAS-associated death domain protein [KO:K02373]
117704983  Casp8; caspase-8 [KO:K04398] [EC:3.4.22.61]
117715167  Bid; BH3-interacting domain death agonist [KO:K04726]
117703834  Bcl2l11; bcl-2-like protein 11 isoform X1 [KO:K16341]
117716348  Bcl2; apoptosis regulator Bcl-2 isoform X1 [KO:K02161]
117722249  Bax; apoptosis regulator BAX isoform X1 [KO:K02159]
117724492  Bak1; bcl-2 homologous antagonist/killer isoform X1 [KO:K14021]
117717119  LOW QUALITY PROTEIN: cytochrome c, somatic-like [KO:K08738]
117700217  cytochrome c-like [KO:K08738]
117701548  LOW QUALITY PROTEIN: cytochrome c, somatic-like [KO:K08738]
117720836  cytochrome c, somatic [KO:K08738]
117704117  cytochrome c, testis-specific [KO:K08738]
117696384  Apaf1; apoptotic protease-activating factor 1 [KO:K02084]
117708916  Casp9; caspase-9 [KO:K04399] [EC:3.4.22.62]
117721984  Casp3; caspase-3 [KO:K02187] [EC:3.4.22.56]
117699427  Cd3e; T-cell surface glycoprotein CD3 epsilon chain [KO:K06451]
117699390  Cd3g; T-cell surface glycoprotein CD3 gamma chain [KO:K06452]
117699353  Cd3d; T-cell surface glycoprotein CD3 delta chain [KO:K06450]
117716585  Cd247; T-cell surface glycoprotein CD3 zeta chain isoform X1 [KO:K06453]
117706839  Psmc2; 26S proteasome regulatory subunit 7 [KO:K03061]
117697399  Psmc1; 26S proteasome regulatory subunit 4 [KO:K03062]
117718037  Psmc4; 26S proteasome regulatory subunit 6B [KO:K03063]
117705763  Psmc6; 26S proteasome regulatory subunit 10B [KO:K03064]
117702928  Psmc3; 26S proteasome regulatory subunit 6A [KO:K03065]
117709903  Psmc5; 26S proteasome regulatory subunit 8 isoform X1 [KO:K03066]
117717524  Psmd2; 26S proteasome non-ATPase regulatory subunit 2 [KO:K03028]
117722368  Psmd1; 26S proteasome non-ATPase regulatory subunit 1 [KO:K03032]
117696122  LOW QUALITY PROTEIN: 26S proteasome non-ATPase regulatory subunit 1-like [KO:K03032]
117711034  Psmd3; 26S proteasome non-ATPase regulatory subunit 3 [KO:K03033]
117711425  Psmd12; 26S proteasome non-ATPase regulatory subunit 12 [KO:K03035]
117711120  Psmd11; 26S proteasome non-ATPase regulatory subunit 11 [KO:K03036]
117705851  Psmd6; 26S proteasome non-ATPase regulatory subunit 6 [KO:K03037]
117723427  Psmd7; 26S proteasome non-ATPase regulatory subunit 7 [KO:K03038]
117709488  Psmd13; 26S proteasome non-ATPase regulatory subunit 13 [KO:K03039]
117706659  Psmd4; 26S proteasome non-ATPase regulatory subunit 4 isoform X1 [KO:K03029]
117704618  Psmd14; 26S proteasome non-ATPase regulatory subunit 14 [KO:K03030]
117724216  Psmd8; 26S proteasome non-ATPase regulatory subunit 8 [KO:K03031]
117702820  Adrm1; proteasomal ubiquitin receptor ADRM1 [KO:K06691]
117720674  Sem1; 26S proteasome complex subunit SEM1 [KO:K10881]
117724686  Tap1; antigen peptide transporter 1 [KO:K05653] [EC:7.4.2.14]
117724741  Tap2; antigen peptide transporter 2 [KO:K05654] [EC:7.4.2.14]
117724483  Tapbp; tapasin [KO:K08058]
117703576  Pdia3; protein disulfide-isomerase A3 [KO:K08056] [EC:5.3.4.1]
117723082  Calr; calreticulin [KO:K08057]
117708852  calreticulin-like [KO:K08057]
117724191  H-2 class I histocompatibility antigen, D-K alpha chain-like isoform X1 [KO:K06751]
117724193  H-2 class I histocompatibility antigen, D-B alpha chain-like isoform X1 [KO:K06751]
117724194  H-2 class I histocompatibility antigen, Q10 alpha chain-like isoform X1 [KO:K06751]
117724195  H-2 class I histocompatibility antigen, D-P alpha chain-like isoform X1 [KO:K06751]
117724198  LOW QUALITY PROTEIN: H-2 class I histocompatibility antigen, L-D alpha chain-like [KO:K06751]
117724199  H-2 class I histocompatibility antigen, D-P alpha chain-like isoform X1 [KO:K06751]
117724200  H-2 class I histocompatibility antigen, D-B alpha chain-like [KO:K06751]
117724203  H-2 class I histocompatibility antigen, D-B alpha chain-like isoform X1 [KO:K06751]
117724204  H-2 class I histocompatibility antigen, D-P alpha chain-like isoform X1 [KO:K06751]
117724206  H-2 class I histocompatibility antigen, D-P alpha chain-like isoform X1 [KO:K06751]
117724208  saoe class I histocompatibility antigen, A alpha chain-like [KO:K06751]
117724209  H-2 class I histocompatibility antigen, L-D alpha chain-like isoform X1 [KO:K06751]
117724217  H-2 class I histocompatibility antigen, Q7 alpha chain-like isoform X1 [KO:K06751]
117724218  saoe class I histocompatibility antigen, A alpha chain-like [KO:K06751]
117724232  H-2 class I histocompatibility antigen, alpha chain-like [KO:K06751]
117724273  H-2 class I histocompatibility antigen, Q7 alpha chain-like [KO:K06751]
117724288  class I histocompatibility antigen, Gogo-B*0102 alpha chain-like [KO:K06751]
117724289  class I histocompatibility antigen, Gogo-B*0102 alpha chain-like [KO:K06751]
117724290  popy Class I histocompatibility antigen, A-1 alpha chain-like [KO:K06751]
117724484  H-2 class I histocompatibility antigen, L-D alpha chain-like isoform X1 [KO:K06751]
117724820  H-2 class I histocompatibility antigen, D-K alpha chain-like isoform X1 [KO:K06751]
117724821  H-2 class I histocompatibility antigen, Q10 alpha chain-like isoform X1 [KO:K06751]
117724824  H-2 class I histocompatibility antigen, alpha chain-like [KO:K06751]
117724825  H-2 class I histocompatibility antigen, Q10 alpha chain-like isoform X1 [KO:K06751]
117724936  saoe class I histocompatibility antigen, A alpha chain-like [KO:K06751]
117701609  H-2 class I histocompatibility antigen, D-P alpha chain-like isoform X1 [KO:K06751]
117701710  H-2 class I histocompatibility antigen, L-D alpha chain-like isoform X1 [KO:K06751]
117702316  H-2 class I histocompatibility antigen, Q10 alpha chain-like [KO:K06751]
117702317  H-2 class I histocompatibility antigen, D-37 alpha chain-like isoform X1 [KO:K06751]
117702602  B2m; beta-2-microglobulin [KO:K08055]
117697075  Snw1; SNW domain-containing protein 1 [KO:K06063]
117697076  SNW domain-containing protein 1-like [KO:K06063]
117697191  SNW domain-containing protein 1-like [KO:K06063]
117716511  LOW QUALITY PROTEIN: SNW domain-containing protein 1-like [KO:K06063]
117720144  SNW domain-containing protein 1-like [KO:K06063]
117720162  SNW domain-containing protein 1-like [KO:K06063]
117720164  SNW domain-containing protein 1-like [KO:K06063]
117720169  SNW domain-containing protein 1-like [KO:K06063]
117695481  SNW domain-containing protein 1-like [KO:K06063]
117699213  Sin3a; paired amphipathic helix protein Sin3a [KO:K11644]
117724593  Hdac2; histone deacetylase 2 [KO:K06067] [EC:3.5.1.98]
117709000  Hdac1; histone deacetylase 1 [KO:K06067] [EC:3.5.1.98]
117697680  Ncor2; nuclear receptor corepressor 2 isoform X1 [KO:K06065]
117712033  Sap30l; histone deacetylase complex subunit SAP30L [KO:K19202]
117721255  Sap30; histone deacetylase complex subunit SAP30 [KO:K19202]
117702954  Cir1; corepressor interacting with RBPJ 1 [KO:K06066]
117704473  Rbpjl; recombining binding protein suppressor of hairless-like protein [KO:K06053]
117712581  Rbpj; recombining binding protein suppressor of hairless isoform X1 [KO:K06053]
117718230  Hes1; transcription factor HES-1 [KO:K06054]
117698141  Fcer2; low affinity immunoglobulin epsilon Fc receptor isoform X1 [KO:K06468]
117708904  Runx3; runt-related transcription factor 3 isoform X1 [KO:K09279]
117719150  Myc; myc proto-oncogene protein [KO:K04377]
117695826  myc proto-oncogene protein-like [KO:K04377]
117695848  myc proto-oncogene protein-like [KO:K04377]
117696009  myc proto-oncogene protein-like [KO:K04377]
117710204  Usp7; ubiquitin carboxyl-terminal hydrolase 7 isoform X1 [KO:K11838] [EC:3.4.19.12]
117696339  Mdm2; E3 ubiquitin-protein ligase Mdm2 isoform X1 [KO:K06643] [EC:2.3.2.27]
117710574  Tp53; cellular tumor antigen p53 [KO:K04451]
117724897  Cdkn1a; cyclin-dependent kinase inhibitor 1 [KO:K06625]
117715599  Gadd45a; growth arrest and DNA damage-inducible protein GADD45 alpha [KO:K04402]
117713452  Gadd45g; growth arrest and DNA damage-inducible protein GADD45 gamma [KO:K04402]
117696104  Gadd45b; growth arrest and DNA damage-inducible protein GADD45 beta [KO:K04402]
117703801  Ddb2; DNA damage-binding protein 2 [KO:K10140]
117700417  Polk; DNA polymerase kappa [KO:K03511] [EC:2.7.7.7]
117716371  Traf5; TNF receptor-associated factor 5 [KO:K09849]
117706649  Pik3ca; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
117693421  Pik3cb; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
117708986  Pik3cd; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform [KO:K00922] [EC:2.7.1.153]
117721973  Pik3r2; phosphatidylinositol 3-kinase regulatory subunit beta isoform X1 [KO:K02649]
117723761  Pik3r1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
117708961  phosphatidylinositol 3-kinase regulatory subunit gamma [KO:K02649]
117697536  Akt1; RAC-alpha serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
117706636  Akt2; RAC-beta serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
117721481  Akt3; RAC-gamma serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
117711275  Map3k14; mitogen-activated protein kinase kinase kinase 14 [KO:K04466] [EC:2.7.11.25]
117709369  Relb; transcription factor RelB [KO:K09253]
117706853  Nfkb2; nuclear factor NF-kappa-B p100 subunit isoform X1 [KO:K04469]
117723297  Tradd; tumor necrosis factor receptor type 1-associated DEATH domain protein isoform X1 [KO:K03171]
117694422  Nfkbib; NF-kappa-B inhibitor beta isoform X1 [KO:K02581]
117722156  Nfkbie; NF-kappa-B inhibitor epsilon isoform X1 [KO:K05872]
117710639  Map2k4; dual specificity mitogen-activated protein kinase kinase 4 isoform X1 [KO:K04430] [EC:2.7.12.2]
117697775  Map2k7; dual specificity mitogen-activated protein kinase kinase 7 isoform X1 [KO:K04431] [EC:2.7.12.2]
117705037  Mapk8; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
117709966  Mapk9; mitogen-activated protein kinase 9 isoform X1 [KO:K04440] [EC:2.7.11.24]
117710914  Traf2; TNF receptor-associated factor 2 [KO:K03173] [EC:2.3.2.27]
117713706  Ripk1; receptor-interacting serine/threonine-protein kinase 1 isoform X1 [KO:K02861] [EC:2.7.11.1]
117710465  Map2k3; dual specificity mitogen-activated protein kinase kinase 3 isoform X1 [KO:K04432] [EC:2.7.12.2]
117710811  Map2k6; dual specificity mitogen-activated protein kinase kinase 6 isoform X1 [KO:K04433] [EC:2.7.12.2]
117724304  Mapk14; mitogen-activated protein kinase 14 isoform X1 [KO:K04441] [EC:2.7.11.24]
117724423  Mapk13; mitogen-activated protein kinase 13 [KO:K04441] [EC:2.7.11.24]
117718601  Mapk12; mitogen-activated protein kinase 12 isoform X1 [KO:K04441] [EC:2.7.11.24]
117718602  Mapk11; mitogen-activated protein kinase 11 [KO:K04441] [EC:2.7.11.24]
117709069  Jun; transcription factor AP-1 [KO:K04448]
117711345  Entpd8; ectonucleoside triphosphate diphosphohydrolase 8 isoform X1 [KO:K01510] [EC:3.6.1.5]
117697720  Entpd1; ectonucleoside triphosphate diphosphohydrolase 1 [KO:K01510] [EC:3.6.1.5]
117725069  Entpd3; ectonucleoside triphosphate diphosphohydrolase 3 [KO:K01510] [EC:3.6.1.5]
117703570  Cd40; tumor necrosis factor receptor superfamily member 5 isoform X1 [KO:K03160]
117702830  Cd44; CD44 antigen isoform X1 [KO:K06256]
117710925  Itgal; integrin alpha-L isoform X1 [KO:K05718]
117714210  Icam1; intercellular adhesion molecule 1 [KO:K06490]
117713571  Vim; vimentin [KO:K07606]
117701024  Tnfaip3; tumor necrosis factor alpha-induced protein 3 isoform X1 [KO:K11859] [EC:3.4.19.12]
117721499  Jak3; tyrosine-protein kinase JAK3 isoform X1 [KO:K11218] [EC:2.7.10.2]
117710477  Stat3; signal transducer and activator of transcription 3 isoform X1 [KO:K04692]
117698663  Lyn; tyrosine-protein kinase Lyn isoform X1 [KO:K05854] [EC:2.7.10.2]
117714378  Syk; tyrosine-protein kinase SYK [KO:K05855] [EC:2.7.10.2]
117699624  Nedd4; E3 ubiquitin-protein ligase NEDD4 isoform X1 [KO:K10591] [EC:2.3.2.26]
117697870  Rac1; ras-related C3 botulinum toxin substrate 1 isoform X1 [KO:K04392]
117694372  Btk; tyrosine-protein kinase BTK [KO:K07370] [EC:2.7.10.2]
117702766  Blnk; B-cell linker protein [KO:K07371]
117723064  Plcg2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 [KO:K05859] [EC:3.1.4.11]
117724054  Skp2; S-phase kinase-associated protein 2 [KO:K03875]
117715314  Cdkn1b; cyclin-dependent kinase inhibitor 1B [KO:K06624]
117711496  Ccnd1; G1/S-specific cyclin-D1 isoform X1 [KO:K04503]
117714829  Ccnd2; G1/S-specific cyclin-D2 [KO:K10151]
117722295  Ccnd3; G1/S-specific cyclin-D3 [KO:K10152]
117696408  Cdk4; cyclin-dependent kinase 4 isoform X1 [KO:K02089] [EC:2.7.11.22]
117720333  Cdk6; cyclin-dependent kinase 6 [KO:K02091] [EC:2.7.11.22]
117706717  Ccna2; cyclin-A2 [KO:K06627]
117707276  Ccna1; cyclin-A1 [KO:K06627]
117698572  Ccne2; G1/S-specific cyclin-E2 isoform X1 [KO:K06626]
117717876  LOW QUALITY PROTEIN: G1/S-specific cyclin-E2-like [KO:K06626]
117712916  Ccne1; G1/S-specific cyclin-E1 [KO:K06626]
117696564  Cdk2; cyclin-dependent kinase 2 isoform X1 [KO:K02206] [EC:2.7.11.22]
117705264  Rb1; retinoblastoma-associated protein [KO:K06618]
117702649  E2f1; transcription factor E2F1 [KO:K17454]
117709432  E2f2; transcription factor E2F2 isoform X1 [KO:K09389]
117713327  E2f3; transcription factor E2F3 [KO:K06620]
Compound
C00076  Calcium cation
C01245  D-myo-Inositol 1,4,5-trisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
Reference
PMID:15510157
  Authors
Young LS, Rickinson AB.
  Title
Epstein-Barr virus: 40 years on.
  Journal
Nat Rev Cancer 4:757-68 (2004)
DOI:10.1038/nrc1452
Reference
PMID:21372216
  Authors
Saha A, Robertson ES
  Title
Epstein-Barr virus-associated B-cell lymphomas: pathogenesis and clinical outcomes.
  Journal
Clin Cancer Res 17:3056-63 (2011)
DOI:10.1158/1078-0432.CCR-10-2578
Reference
PMID:21429244
  Authors
Ning S
  Title
Innate immune modulation in EBV infection.
  Journal
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Related
pathway
anu03050  Proteasome
anu04010  MAPK signaling pathway
anu04020  Calcium signaling pathway
anu04064  NF-kappa B signaling pathway
anu04110  Cell cycle
anu04115  p53 signaling pathway
anu04210  Apoptosis
anu04612  Antigen processing and presentation
anu04620  Toll-like receptor signaling pathway
anu04622  RIG-I-like receptor signaling pathway
anu04630  JAK-STAT signaling pathway
anu04662  B cell receptor signaling pathway
KO pathway
ko05169   
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