KEGG   PATHWAY: btax05166
Entry
btax05166                   Pathway                                
Name
Human T-cell leukemia virus 1 infection - Budorcas taxicolor (takin)
Description
Human T-cell leukemia virus type 1 (HTLV-1) is a pathogenic retrovirus that is associated with adult T-cell leukemia/lymphoma (ATL). It is also strongly implicated in non-neoplastic chronic inflammatory diseases such as HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). Expression of Tax, a viral regulatory protein is critical to the pathogenesis. Tax is a transcriptional co-factor that interfere several signaling pathways related to anti-apoptosis or cell proliferation. The modulation of the signaling by Tax involve its binding to transcription factors like CREB/ATF, NF-kappa B, and SRF.
Class
Human Diseases; Infectious disease: viral
Pathway map
btax05166  Human T-cell leukemia virus 1 infection
btax05166

Organism
Budorcas taxicolor (takin) [GN:btax]
Gene
128044406  SLC2A1; solute carrier family 2, facilitated glucose transporter member 1 isoform X1 [KO:K07299]
128058338  NRP1; neuropilin-1 isoform X1 [KO:K06724]
128059120  MYC; myc proto-oncogene protein [KO:K04377]
128043712  TRRAP; transformation/transcription domain-associated protein isoform X1 [KO:K08874]
128068674  KAT5; histone acetyltransferase KAT5 isoform X1 [KO:K11304] [EC:2.3.1.48]
128048410  CCND2; G1/S-specific cyclin-D2 [KO:K10151]
128070817  ITGAL; integrin alpha-L [KO:K05718]
128047159  ITGB2; integrin beta-2 [KO:K06464]
128050899  intercellular adhesion molecule 1 [KO:K06490]
128051541  LOW QUALITY PROTEIN: intercellular adhesion molecule 1-like [KO:K06490]
128068689  HRAS; GTPase HRas isoform X1 [KO:K02833]
128047937  KRAS; GTPase KRas [KO:K07827]
128044537  NRAS; GTPase NRas [KO:K07828]
128054045  MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 [KO:K04368] [EC:2.7.12.2]
128050664  MAP2K2; dual specificity mitogen-activated protein kinase kinase 2 [KO:K04369] [EC:2.7.12.2]
128043958  MAPK3; mitogen-activated protein kinase 3 [KO:K04371] [EC:2.7.11.24]
128062160  MAPK1; mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
128048680  CD4; T-cell surface glycoprotein CD4 [KO:K06454]
128052212  TLN1; talin-1 [KO:K06271]
128054345  TLN2; talin-2 isoform X1 [KO:K06271]
128051428  RANBP3; ran-binding protein 3 isoform X1 [KO:K15304]
128069900  GTP-binding nuclear protein Ran-like [KO:K07936]
128044472  GTP-binding nuclear protein Ran-like [KO:K07936]
128051213  GTP-binding nuclear protein Ran-like [KO:K07936]
128046602  GTP-binding nuclear protein Ran-like [KO:K07936]
128053213  GTP-binding nuclear protein Ran [KO:K07936]
128054180  GTP-binding nuclear protein Ran-like [KO:K07936]
128062157  RAN; GTP-binding nuclear protein Ran [KO:K07936]
128068590  GTP-binding nuclear protein Ran [KO:K07936]
128055490  XPO1; exportin-1 [KO:K14290]
128050932  CALR; calreticulin [KO:K08057]
128050643  CANX; calnexin [KO:K08054]
128052144  PPP3CC; serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform isoform X1 [KO:K04348] [EC:3.1.3.16]
128047312  PPP3CB; serine/threonine-protein phosphatase 2B catalytic subunit beta isoform [KO:K04348] [EC:3.1.3.16]
128049447  PPP3CA; protein phosphatase 3 catalytic subunit alpha isoform X1 [KO:K04348] [EC:3.1.3.16]
128052606  PPP3R2; calcineurin subunit B type 2 [KO:K06268]
128055318  PPP3R1; calcineurin subunit B type 1 [KO:K06268]
128067290  NFATC1; nuclear factor of activated T-cells, cytoplasmic 1 isoform X1 [KO:K04446]
128058335  NFATC2; nuclear factor of activated T-cells, cytoplasmic 2 isoform X1 [KO:K17332]
128064208  NFATC3; nuclear factor of activated T-cells, cytoplasmic 3 isoform X1 [KO:K17333]
128054080  NFATC4; nuclear factor of activated T-cells, cytoplasmic 4 [KO:K17334]
128048204  IL2RB; interleukin-2 receptor subunit beta [KO:K05069]
128070243  IL2RG; cytokine receptor common subunit gamma [KO:K05070]
128044816  JAK1; tyrosine-protein kinase JAK1 [KO:K11217] [EC:2.7.10.2]
128051234  JAK3; tyrosine-protein kinase JAK3 [KO:K11218] [EC:2.7.10.2]
128065012  signal transducer and activator of transcription 5A [KO:K11223]
128064838  STAT5B; signal transducer and activator of transcription 5B isoform X1 [KO:K11224]
128062529  IL2; interleukin-2 [KO:K05429]
128050979  H-2 class I histocompatibility antigen, Q10 alpha chain-like [KO:K06751]
128055236  LOW QUALITY PROTEIN: BOLA class I histocompatibility antigen, alpha chain BL3-7-like [KO:K06751]
128055280  LOW QUALITY PROTEIN: BOLA class I histocompatibility antigen, alpha chain BL3-7-like [KO:K06751]
128055281  LOW QUALITY PROTEIN: BOLA class I histocompatibility antigen, alpha chain BL3-7-like [KO:K06751]
128055305  BOLA class I histocompatibility antigen, alpha chain BL3-7-like [KO:K06751]
128053799  beta-2-microglobulin [KO:K08055]
128053800  beta-2-microglobulin [KO:K08055]
128045313  FDPS; farnesyl pyrophosphate synthase isoform X1 [KO:K00787] [EC:2.5.1.1 2.5.1.10]
128059179  LOW QUALITY PROTEIN: farnesyl pyrophosphate synthase-like [KO:K00787] [EC:2.5.1.1 2.5.1.10]
128050636  VDAC1; voltage-dependent anion-selective channel protein 1 isoform X1 [KO:K05862]
128058634  voltage-dependent anion-selective channel protein 1-like [KO:K05862]
128069760  SLC25A5; ADP/ATP translocase 2 [KO:K05863]
128070620  SLC25A6; ADP/ATP translocase 3 [KO:K05863]
128068228  SLC25A4; ADP/ATP translocase 1 [KO:K05863]
128062431  SLC25A31; ADP/ATP translocase 4 [KO:K05863]
128059118  voltage-dependent anion-selective channel protein 2-like [KO:K15040]
128047278  VDAC2; voltage-dependent anion-selective channel protein 2 [KO:K15040]
128068182  VDAC3; voltage-dependent anion-selective channel protein 3 [KO:K15041]
128048545  TSPO; translocator protein [KO:K05770]
128055619  TSPO2; LOW QUALITY PROTEIN: translocator protein 2 [KO:K05770]
128063001  VAC14; protein VAC14 homolog isoform X1 [KO:K15305]
128062037  RANBP1; ran-specific GTPase-activating protein [KO:K15306]
128063517  MAD1L1; mitotic spindle assembly checkpoint protein MAD1 [KO:K06679]
128049881  MAD2L1; mitotic spindle assembly checkpoint protein MAD2A isoform X1 [KO:K02537]
128054489  BUB1B; mitotic checkpoint serine/threonine-protein kinase BUB1 beta [KO:K06637] [EC:2.7.11.1]
128067813  BUB3; mitotic checkpoint protein BUB3 isoform X1 [KO:K02180]
128055163  ANAPC1; anaphase-promoting complex subunit 1 [KO:K03348]
128055109  ANAPC2; anaphase-promoting complex subunit 2 [KO:K03349]
128064760  CDC27; cell division cycle protein 27 homolog [KO:K03350]
128049612  ANAPC4; anaphase-promoting complex subunit 4 [KO:K03351]
128062231  ANAPC5; anaphase-promoting complex subunit 5 [KO:K03352]
128057556  CDC16; cell division cycle protein 16 homolog isoform X1 [KO:K03353]
128062568  ANAPC7; anaphase-promoting complex subunit 7 isoform X1 [KO:K03354]
128050894  CDC23; cell division cycle protein 23 homolog [KO:K03355]
128070329  anaphase-promoting complex subunit 10-like [KO:K03357]
128062340  ANAPC10; anaphase-promoting complex subunit 10 [KO:K03357]
128069039  anaphase-promoting complex subunit 10-like [KO:K03357]
128064532  ANAPC11; anaphase-promoting complex subunit 11 [KO:K03358]
128052686  CDC26; anaphase-promoting complex subunit CDC26 [KO:K03359]
128050778  ANAPC13; anaphase-promoting complex subunit 13 [KO:K12456]
128060036  ANAPC15; anaphase-promoting complex subunit 15 [KO:K25228]
128048135  anaphase-promoting complex subunit 15-like [KO:K25228]
128047354  ANAPC16; anaphase-promoting complex subunit 16 [KO:K25229]
128045153  CDC20; cell division cycle protein 20 homolog [KO:K03363]
128051529  PTTG1; securin [KO:K06635]
128048511  ESPL1; separin [KO:K02365] [EC:3.4.22.49]
128054390  CCNB2; G2/mitotic-specific cyclin-B2 [KO:K21770]
128052514  CDKN2B; cyclin-dependent kinase 4 inhibitor B [KO:K04685]
128052529  cyclin-dependent kinase inhibitor 2A-like [KO:K06621]
128047322  CDK4; cyclin-dependent kinase 4 [KO:K02089] [EC:2.7.11.22]
128069030  CCND1; G1/S-specific cyclin-D1 [KO:K04503]
128055411  CCND3; G1/S-specific cyclin-D3 [KO:K10152]
128056953  CDKN1A; cyclin-dependent kinase inhibitor 1 [KO:K06625]
128049924  CCNA2; cyclin-A2 [KO:K06627]
128057751  CCNA1; cyclin-A1 [KO:K06627]
128063478  CCNE1; G1/S-specific cyclin-E1 [KO:K06626]
128059332  CCNE2; G1/S-specific cyclin-E2 [KO:K06626]
128047622  CDK2; cyclin-dependent kinase 2 isoform X1 [KO:K02206] [EC:2.7.11.22]
128057539  RB1; retinoblastoma-associated protein isoform X1 [KO:K06618]
128058399  E2F1; transcription factor E2F1 [KO:K17454]
128043619  E2F2; transcription factor E2F2 [KO:K09389]
128056580  E2F3; transcription factor E2F3 [KO:K06620]
128060504  ATM; serine-protein kinase ATM [KO:K04728] [EC:2.7.11.1]
128053092  ATR; serine/threonine-protein kinase ATR [KO:K06640] [EC:2.7.11.1]
128068939  CHEK1; LOW QUALITY PROTEIN: serine/threonine-protein kinase Chk1 [KO:K02216] [EC:2.7.11.1]
128071171  serine/threonine-protein kinase Chk2 [KO:K06641] [EC:2.7.11.1]
128062388  CHEK2; serine/threonine-protein kinase Chk2 [KO:K06641] [EC:2.7.11.1]
128049822  LOW QUALITY PROTEIN: cellular tumor antigen p53-like [KO:K04451]
128064672  TP53; cellular tumor antigen p53 [KO:K04451]
128050540  PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta [KO:K02649]
128044474  PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma [KO:K02649]
128066235  PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha [KO:K02649]
128045803  PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
128061813  PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
128068699  PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
128063870  AKT2; RAC-beta serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
128067048  AKT1; RAC-alpha serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
128061491  AKT3; RAC-gamma serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
128053795  DLG1; disks large homolog 1 [KO:K12076]
128068055  PTEN; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
128056772  TNF; tumor necrosis factor [KO:K03156]
128047668  TNFRSF1A; tumor necrosis factor receptor superfamily member 1A isoform X1 [KO:K03158]
128065982  MAP3K1; mitogen-activated protein kinase kinase kinase 1 [KO:K04416] [EC:2.7.11.25]
128064467  MAP2K4; dual specificity mitogen-activated protein kinase kinase 4 isoform X1 [KO:K04430] [EC:2.7.12.2]
128051495  MAPK9; mitogen-activated protein kinase 9 isoform X1 [KO:K04440] [EC:2.7.11.24]
128047244  MAPK8; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
128049619  MAPK10; mitogen-activated protein kinase 10 [KO:K04440] [EC:2.7.11.24]
128044447  JUN; transcription factor Jun [KO:K04448]
128060945  MMP7; matrilysin [KO:K01397] [EC:3.4.24.23]
128056062  IL1R1; interleukin-1 receptor type 1 isoform X1 [KO:K04386]
128056702  IL1R2; interleukin-1 receptor type 2 [KO:K04387]
128060506  T-cell surface glycoprotein CD3 delta chain [KO:K06450]
128060834  T-cell surface glycoprotein CD3 epsilon chain [KO:K06451]
128060507  T-cell surface glycoprotein CD3 gamma chain [KO:K06452]
128064421  MAP3K3; mitogen-activated protein kinase kinase kinase 3 isoform X1 [KO:K04421] [EC:2.7.11.25]
128067677  CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1 [KO:K04467] [EC:2.7.11.10]
128068238  IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1 [KO:K07209] [EC:2.7.11.10]
128069947  IKBKG; NF-kappa-B essential modulator isoform X1 [KO:K07210]
128066643  NFKBIA; NF-kappa-B inhibitor alpha [KO:K04734]
128049417  NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1 [KO:K02580]
128068546  RELA; transcription factor p65 [KO:K04735]
128064583  GPS2; G protein pathway suppressor 2 isoform X1 [KO:K15307]
128047522  LTBR; tumor necrosis factor receptor superfamily member 3 [KO:K03159]
128058688  CD40; tumor necrosis factor receptor superfamily member 5 [KO:K03160]
128048934  TNFRSF13C; tumor necrosis factor receptor superfamily member 13C [KO:K05151]
128065013  MAP3K14; mitogen-activated protein kinase kinase kinase 14 [KO:K04466] [EC:2.7.11.25]
128063412  RELB; LOW QUALITY PROTEIN: transcription factor RelB [KO:K09253]
128067674  NFKB2; nuclear factor NF-kappa-B p100 subunit isoform X1 [KO:K04469]
128063128  ZFP36; mRNA decay activator protein ZFP36 [KO:K15308]
128058762  IL2RA; interleukin-2 receptor subunit alpha [KO:K05068]
128062532  IL15; interleukin-15 [KO:K05433]
128058419  IL15RA; interleukin-15 receptor subunit alpha isoform X1 [KO:K05074]
128046952  IL6; interleukin-6 [KO:K05405]
128051607  CSF2; granulocyte-macrophage colony-stimulating factor [KO:K05427]
128056921  LTA; lymphotoxin-alpha [KO:K05468]
128058470  BCL2L1; bcl-2-like protein 1 [KO:K04570]
128059210  LOW QUALITY PROTEIN: bcl-2-like protein 1 [KO:K04570]
128070186  XIAP; E3 ubiquitin-protein ligase XIAP [KO:K04725] [EC:2.3.2.27]
128063320  TGFB1; transforming growth factor beta-1 proprotein [KO:K13375]
128061503  TGFB2; transforming growth factor beta-2 proprotein [KO:K13376]
128053888  TGFB3; transforming growth factor beta-3 proprotein [KO:K13377]
128051987  TGFBR1; TGF-beta receptor type-1 [KO:K04674] [EC:2.7.11.30]
128048354  TGFBR2; TGF-beta receptor type-2 [KO:K04388] [EC:2.7.11.30]
128067292  SMAD2; mothers against decapentaplegic homolog 2 [KO:K04500]
128054493  SMAD3; mothers against decapentaplegic homolog 3 [KO:K23605]
128067298  SMAD4; mothers against decapentaplegic homolog 4 [KO:K04501]
128046764  ADCY1; adenylate cyclase type 1 [KO:K08041] [EC:4.6.1.1]
128066123  ADCY2; adenylate cyclase type 2 [KO:K08042] [EC:4.6.1.1]
128056879  ADCY3; adenylate cyclase type 3 [KO:K08043] [EC:4.6.1.1]
128053854  ADCY4; adenylate cyclase type 4 isoform X1 [KO:K08044] [EC:4.6.1.1]
128067499  ADCY5; adenylate cyclase type 5 [KO:K08045] [EC:4.6.1.1]
128047362  ADCY6; adenylate cyclase type 6 isoform X1 [KO:K08046] [EC:4.6.1.1]
128063240  ADCY7; adenylate cyclase type 7 [KO:K08047] [EC:4.6.1.1]
128059256  ADCY8; adenylate cyclase type 8 [KO:K08048] [EC:4.6.1.1]
128043555  ADCY9; adenylate cyclase type 9 [KO:K08049] [EC:4.6.1.1]
128050339  PRKACA; cAMP-dependent protein kinase catalytic subunit alpha [KO:K04345] [EC:2.7.11.11]
128044465  PRKACB; cAMP-dependent protein kinase catalytic subunit beta [KO:K04345] [EC:2.7.11.11]
128047821  NFYB; nuclear transcription factor Y subunit beta [KO:K08065]
128056359  LOW QUALITY PROTEIN: HLA class II histocompatibility antigen, DQ alpha 2 chain-like [KO:K06752]
128056564  HLA class II histocompatibility antigen, DM beta chain [KO:K06752]
128056652  HLA class II histocompatibility antigen, DM alpha chain [KO:K06752]
128056806  LOW QUALITY PROTEIN: rano class II histocompatibility antigen, A beta chain-like [KO:K06752]
128056812  HLA class II histocompatibility antigen, DO beta chain [KO:K06752]
128055329  boLa class II histocompatibility antigen, DQB*0101 beta chain [KO:K06752]
128055330  boLa class II histocompatibility antigen, DQB*0101 beta chain-like [KO:K06752]
128055331  SLA class II histocompatibility antigen, DQ haplotype D alpha chain-like [KO:K06752]
128055332  SLA class II histocompatibility antigen, DQ haplotype D alpha chain-like [KO:K06752]
128055370  DLA class II histocompatibility antigen, DR-1 beta chain-like [KO:K06752]
128055541  HLA class II histocompatibility antigen, DO alpha chain-like [KO:K06752]
128055605  DLA class II histocompatibility antigen, DR-1 beta chain-like [KO:K06752]
128055814  DLA class II histocompatibility antigen, DR-1 beta chain-like [KO:K06752]
128056011  mamu class II histocompatibility antigen, DR alpha chain [KO:K06752]
128055386  SRF; serum response factor [KO:K04378]
128061610  ELK4; ETS domain-containing protein Elk-4 [KO:K04376]
128070470  ELK1; ETS domain-containing protein Elk-1 [KO:K04375]
128060403  SPI1; transcription factor PU.1 isoform X1 [KO:K09438]
128068539  ETS1; protein C-ets-1 isoform X1 [KO:K02678]
128055078  ETS2; protein C-ets-2 isoform X1 [KO:K21932]
128056585  TATA-box-binding protein-like [KO:K03120]
128053226  TBP; TATA-box-binding protein [KO:K03120]
128053400  TBPL1; TATA box-binding protein-like 1 [KO:K03120]
128054498  TBPL2; TATA box-binding protein-like 2 [KO:K03120]
128053951  FOS; protein c-Fos [KO:K04379]
128050654  EGR1; early growth response protein 1 [KO:K09203]
128068636  FOSL1; fos-related antigen 1 [KO:K04502]
128048574  EGR2; E3 SUMO-protein ligase EGR2 [KO:K12496]
128071103  cyclic AMP-responsive element-binding protein 1 isoform X1 [KO:K05870]
128061475  CREB1; cyclic AMP-responsive element-binding protein 1 isoform X1 [KO:K05870]
128044759  CREB3L4; cyclic AMP-responsive element-binding protein 3-like protein 4 [KO:K09048]
128051508  CREB3L3; cyclic AMP-responsive element-binding protein 3-like protein 3 [KO:K09048]
128052214  CREB3; cyclic AMP-responsive element-binding protein 3 isoform X1 [KO:K09048]
128046532  CREB3L2; cyclic AMP-responsive element-binding protein 3-like protein 2 [KO:K09048]
128060385  CREB3L1; cyclic AMP-responsive element-binding protein 3-like protein 1 [KO:K09048]
128065610  ATF2; cyclic AMP-dependent transcription factor ATF-2 isoform X1 [KO:K04450]
128047885  ATF4; cyclic AMP-dependent transcription factor ATF-4 [KO:K04374]
128048350  LOW QUALITY PROTEIN: cyclic AMP-dependent transcription factor ATF-4-like [KO:K04374]
128046584  CREB5; cyclic AMP-responsive element-binding protein 5 isoform X1 [KO:K09047]
128056429  ATF6B; cyclic AMP-dependent transcription factor ATF-6 beta isoform X1 [KO:K09049]
128050750  CRTC1; CREB-regulated transcription coactivator 1 isoform X1 [KO:K15309]
128044579  CRTC2; CREB-regulated transcription coactivator 2 isoform X1 [KO:K16333]
128066613  CRTC3; CREB-regulated transcription coactivator 3 isoform X1 [KO:K16334]
128043638  CREBBP; CREB-binding protein isoform X1 [KO:K04498] [EC:2.3.1.48]
128047516  EP300; histone acetyltransferase p300 [KO:K04498] [EC:2.3.1.48]
128044096  KAT2B; histone acetyltransferase KAT2B [KO:K06062] [EC:2.3.1.48]
128064663  KAT2A; histone acetyltransferase KAT2A isoform X1 [KO:K06062] [EC:2.3.1.48]
128050287  TCF3; transcription factor E2-alpha isoform X1 [KO:K09063]
128068217  POLB; DNA polymerase beta isoform X1 [KO:K02330] [EC:2.7.7.7 4.2.99.-]
128062412  LCK; tyrosine-protein kinase Lck [KO:K05856] [EC:2.7.10.2]
128064207  BAX; apoptosis regulator BAX [KO:K02159]
128044912  CDKN2C; cyclin-dependent kinase 4 inhibitor C [KO:K06622]
128066195  TERT; telomerase reverse transcriptase [KO:K11126] [EC:2.7.7.49]
128066197  MSX2; homeobox protein MSX-2 [KO:K09341]
128049766  MSX1; homeobox protein MSX-1 [KO:K09341]
Compound
C00027  Hydrogen peroxide
C00076  Calcium cation
C00238  Potassium cation
C00575  3',5'-Cyclic AMP
C05981  Phosphatidylinositol-3,4,5-trisphosphate
Reference
PMID:17384582
  Authors
Matsuoka M, Jeang KT
  Title
Human T-cell leukaemia virus type 1 (HTLV-1) infectivity and cellular transformation.
  Journal
Nat Rev Cancer 7:270-80 (2007)
DOI:10.1038/nrc2111
Reference
PMID:16155604
  Authors
Grassmann R, Aboud M, Jeang KT
  Title
Molecular mechanisms of cellular transformation by HTLV-1 Tax.
  Journal
Oncogene 24:5976-85 (2005)
DOI:10.1038/sj.onc.1208978
Reference
PMID:18702816
  Authors
Boxus M, Twizere JC, Legros S, Dewulf JF, Kettmann R, Willems L
  Title
The HTLV-1 Tax interactome.
  Journal
Retrovirology 5:76 (2008)
DOI:10.1186/1742-4690-5-76
Reference
PMID:21994754
  Authors
Jones KS, Lambert S, Bouttier M, Benit L, Ruscetti FW, Hermine O, Pique C
  Title
Molecular aspects of HTLV-1 entry: functional domains of the HTLV-1 surface subunit (SU) and their relationships to the entry receptors.
  Journal
Viruses 3:794-810 (2011)
DOI:10.3390/v3060794
Reference
PMID:21114861
  Authors
Ghez D, Lepelletier Y, Jones KS, Pique C, Hermine O
  Title
Current concepts regarding the HTLV-1 receptor complex.
  Journal
Retrovirology 7:99 (2010)
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Related
pathway
btax03013  Nucleocytoplasmic transport
btax04010  MAPK signaling pathway
btax04064  NF-kappa B signaling pathway
btax04110  Cell cycle
btax04115  p53 signaling pathway
btax04151  PI3K-Akt signaling pathway
btax04210  Apoptosis
btax04350  TGF-beta signaling pathway
btax04612  Antigen processing and presentation
btax04660  T cell receptor signaling pathway
btax04668  TNF signaling pathway
KO pathway
ko05166   
LinkDB

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