KEGG   PATHWAY: bta05164
Entry
bta05164                    Pathway                                
Name
Influenza A - Bos taurus (cow)
Description
Influenza is a contagious respiratory disease caused by influenza virus infection. Influenza A virus is responsible for both annual seasonal epidemics and periodic worldwide pandemics. Novel strains that cause pandemics arise from avian influenza virus by genetic reassortment among influenza viruses and two surface glycoproteins HA and NA form the basis of serologically distinct virus types. The innate immune system recognizes invaded virus through multiple mechanisms. Viral non-structural NS1 protein is a multifunctional virulence factor that interfere IFN-mediated antiviral response. It inhibits IFN production by blocking activation of transcription factors such as NF-kappa B and IRF3. NS1 further inhibits the activation of IFN-induced antiviral genes. PB1-F2 protein is another virulence factor that induce apoptosis of infected cells, which results in life-threatening bronchiolitis.
Class
Human Diseases; Infectious disease: viral
Pathway map
bta05164  Influenza A
bta05164

Organism
Bos taurus (cow) [GN:bta]
Gene
281545  TPSB2; tryptase beta-2 precursor [KO:K01340] [EC:3.4.21.59]
786948  tryptase-2-like precursor [KO:K01340] [EC:3.4.21.59]
280897  PLG; plasminogen precursor [KO:K01315] [EC:3.4.21.7]
282603  PRSS2; anionic trypsin precursor [KO:K01312] [EC:3.4.21.4]
780933  PRSS1; serine protease 1 precursor [KO:K01312] [EC:3.4.21.4]
615026  serine protease 1 [KO:K01312] [EC:3.4.21.4]
511037  TMPRSS2; transmembrane protease serine 2 [KO:K09633] [EC:3.4.21.122]
513343  TMPRSS4; transmembrane protease serine 4 [KO:K09635] [EC:3.4.21.-]
521615  TMPRSS11D; transmembrane protease serine 11D isoform X3 [KO:K09641] [EC:3.4.21.-]
282325  PRKCB; protein kinase C beta type [KO:K19662] [EC:2.7.11.13]
654488  OAS1Y; 2'-5'-oligoadenylate synthase 1 [KO:K14216] [EC:2.7.7.84]
529660  OAS2; 2'-5'-oligoadenylate synthase 2 [KO:K14216] [EC:2.7.7.84]
347699  OAS1X; 2',5'-oligoadenylate synthetase 1, 40/46kDa [KO:K14216] [EC:2.7.7.84]
519922  OAS1Z; 2',5'-oligoadenylate synthetase 1 [KO:K14216] [EC:2.7.7.84]
100048947  RNASEL; 2-5A-dependent ribonuclease [KO:K01165]
538426  DNAJB1; dnaJ homolog subfamily B member 1 [KO:K09507]
286770  DNAJC3; dnaJ homolog subfamily C member 3 precursor [KO:K09523]
347700  EIF2AK2; interferon-induced, double-stranded RNA-activated protein kinase [KO:K16195] [EC:2.7.11.1]
327694  EIF2S1; eukaryotic translation initiation factor 2 subunit 1 [KO:K03237]
510923  TRIM25; E3 ubiquitin/ISG15 ligase TRIM25 [KO:K10652] [EC:2.3.2.27]
504760  RIGI; antiviral innate immune response receptor RIG-I isoform X1 [KO:K12646] [EC:5.6.2.6]
535490  IFIH1; interferon-induced helicase C domain-containing protein 1 [KO:K12647] [EC:5.6.2.6]
539974  NLRX1; NLR family member X1 [KO:K12653]
618508  MAVS; mitochondrial antiviral-signaling protein [KO:K12648]
281073  CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [KO:K04467] [EC:2.7.11.10]
281854  IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [KO:K07209] [EC:2.7.11.10]
281855  IKBKG; NF-kappa-B essential modulator [KO:K07210]
525408  NFKBIB; NF-kappa-B inhibitor beta [KO:K02581]
282291  NFKBIA; NF-kappa-B inhibitor alpha [KO:K04734]
616115  NFKB1; nuclear factor NF-kappa-B p105 subunit [KO:K02580]
508233  RELA; transcription factor p65 [KO:K04735]
281942  CALCOCO2; calcium-binding and coiled-coil domain-containing protein 2 [KO:K21348]
281535  TLR3; toll-like receptor 3 precursor [KO:K05401]
510427  TICAM1; TIR domain-containing adapter molecule 1 [KO:K05842]
506182  TRAF3; TNF receptor-associated factor 3 [KO:K03174]
533141  TBK1; serine/threonine-protein kinase TBK1 [KO:K05410] [EC:2.7.11.10]
533216  IKBKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [KO:K07211] [EC:2.7.11.10]
516979  IRF3; interferon regulatory factor 3 [KO:K05411]
505453  CREBBP; CREB-binding protein [KO:K04498] [EC:2.3.1.48]
112446776  EP300; histone acetyltransferase p300 [KO:K04498] [EC:2.3.1.48]
281536  TLR4; toll-like receptor 4 precursor [KO:K10160]
493686  TLR7; toll-like receptor 7 [KO:K05404]
444881  MYD88; myeloid differentiation primary response protein MyD88 [KO:K04729]
533692  IRAK4; interleukin-1 receptor-associated kinase 4 [KO:K04733] [EC:2.7.11.1]
100125591  IRF7; interferon regulatory factor 7 [KO:K09447]
281250  IL1A; interleukin-1 alpha precursor [KO:K04383]
281251  IL1B; interleukin-1 beta precursor [KO:K04519]
280826  IL6; interleukin-6 precursor [KO:K05405]
281856  IL12A; interleukin-12 subunit alpha precursor [KO:K05406]
281857  IL12B; interleukin-12 subunit beta precursor [KO:K05425]
280943  TNF; tumor necrosis factor [KO:K03156]
280828  CXCL8; interleukin-8 precursor [KO:K10030]
281043  CCL2; C-C motif chemokine 2 precursor [KO:K14624]
327712  CCL5; C-C motif chemokine 5 precursor [KO:K12499]
615107  CXCL10; C-X-C motif chemokine 10 precursor [KO:K12671]
281839  ICAM1; intercellular adhesion molecule 1 precursor [KO:K06490]
281236  IFNAC; interferon alpha-C precursor [KO:K05414]
510726  IFNA16; interferon alpha-H [KO:K05414]
523244  interferon alpha-B-like [KO:K05414]
517108  interferon alpha-2 [KO:K05414]
618947  interferon alpha-B-like [KO:K05414]
787343  interferon alpha-2 [KO:K05414]
515951  IFNAA; interferon alpha-A precursor [KO:K05414]
100329207  IFNAH; interferon alpha-H precursor [KO:K05414]
100335490  interferon alpha-G-like [KO:K05414]
100329204  IFNAD; interferon alpha-D [KO:K05414]
100329206  IFNAG; interferon alpha-G precursor [KO:K05414]
100329210  INFAF; interferon alpha-F precursor [KO:K05414]
783912  interferon alpha-H [KO:K05414]
617556  LOW QUALITY PROTEIN: interferon alpha-1-like [KO:K05414]
132345931  interferon alpha-H-like [KO:K05414]
281845  IFNB1; interferon beta precursor [KO:K05415]
525550  interferon beta-2 [KO:K05415]
517016  interferon beta-2 precursor [KO:K05415]
784525  interferon beta-2 [KO:K05415]
618946  IFNB3; interferon beta-3 precursor [KO:K05415]
100848709  interferon beta-3 [KO:K05415]
616977  interferon beta-2 [KO:K05415]
112441480  interferon beta-3 [KO:K05415]
112447877  interferon beta-3 [KO:K05415]
112447878  interferon beta-3 [KO:K05415]
112447879  interferon beta-3 [KO:K05415]
112447880  interferon beta-3 [KO:K05415]
112441471  interferon beta [KO:K05415]
282257  IFNAR1; interferon alpha/beta receptor 1 precursor [KO:K05130]
282258  IFNAR2; interferon alpha/beta receptor 2 precursor [KO:K05131]
537201  JAK1; tyrosine-protein kinase JAK1 [KO:K11217] [EC:2.7.10.2]
512484  TYK2; non-receptor tyrosine-protein kinase TYK2 [KO:K11219] [EC:2.7.10.2]
282081  SOCS3; suppressor of cytokine signaling 3 [KO:K04696]
510814  STAT1; signal transducer and activator of transcription 1-alpha/beta [KO:K11220]
511023  STAT2; signal transducer and activator of transcription 2 [KO:K11221]
509855  IRF9; interferon regulatory factor 9 [KO:K04693]
280872  MX1; interferon-induced GTP-binding protein Mx1 [KO:K14754]
280873  MX2; interferon-induced GTP-binding protein Mx2 [KO:K14754]
505134  ADAR; double-stranded RNA-specific adenosine deaminase isoform X2 [KO:K12968] [EC:3.5.4.37]
100138545  PML; protein PML [KO:K10054] [EC:2.3.2.-]
281237  IFNG; interferon gamma precursor [KO:K04687]
508619  IFNGR1; interferon gamma receptor 1 precursor [KO:K05132]
514889  IFNGR2; interferon gamma receptor 2 isoform X1 [KO:K05133]
525246  JAK2; tyrosine-protein kinase JAK2 isoform X1 [KO:K04447] [EC:2.7.10.2]
508720  CIITA; MHC class II transactivator isoform X1 [KO:K08060] [EC:2.7.11.1]
282490  BOLA-DMA; HLA class II histocompatibility antigen, DM alpha chain precursor [KO:K06752]
282491  BOLA-DMB; major histocompatibility complex, class II, DM beta precursor [KO:K06752]
282493  BOLA-DOB; HLA class II histocompatibility antigen, DO beta chain precursor [KO:K06752]
282494  BOLA-DQA5; major histocompatibility complex, class II, DQ alpha 5 precursor [KO:K06752]
282495  BOLA-DQB; major histocompatibility complex, class II, DQ beta precursor [KO:K06752]
282498  BOLA-DYB; major histocompatibility complex, class II, DY beta precursor [KO:K06752]
282535  BOLA-DQA2; major histocompatibility complex, class II, DQ alpha 2 [KO:K06752]
282530  BOLA-DRB3; major histocompatibility complex, class II, DRB3 [KO:K06752]
525727  BOLA-DOA; HLA class II histocompatibility antigen, DO alpha chain precursor [KO:K06752]
506214  BOLA-DRA; major histocompatibility complex, class II, DR alpha precursor [KO:K06752]
539241  BLA-DQB; boLa class II histocompatibility antigen, DQB*0101 beta chain precursor [KO:K06752]
100848815  SLA class II histocompatibility antigen, DQ haplotype D alpha chain-like precursor [KO:K06752]
282497  BOLA-DYA; major histocompatibility complex, class II, DY alpha precursor [KO:K06752]
618722  DSB; MHC class II antigen DS beta [KO:K06752]
538700  BOLA-DRB2; HLA class II histocompatibility antigen, DR beta 5 chain isoform X3 [KO:K06752]
538639  NLRP3; NACHT, LRR and PYD domains-containing protein 3 [KO:K12800]
282846  PYCARD; apoptosis-associated speck-like protein containing a CARD [KO:K12799]
514214  CASP1; caspase-1 isoform X1 [KO:K01370] [EC:3.4.22.36]
281249  IL18; interleukin-18 [KO:K05482]
507054  IL33; interleukin-33 [KO:K12967]
282308  PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta [KO:K02649]
286865  PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma [KO:K02649]
282307  PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha [KO:K02649]
282306  PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
517948  PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
504531  PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform [KO:K00922] [EC:2.7.1.153]
534923  AKT2; RAC-beta serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
280991  AKT1; RAC-alpha serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
100137872  AKT3; RAC-gamma serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
540547  CCND3; G1/S-specific cyclin-D3 [KO:K10152]
510618  CDK4; cyclin-dependent kinase 4 [KO:K02089] [EC:2.7.11.22]
511754  CDK6; cyclin-dependent kinase 6 [KO:K02091] [EC:2.7.11.22]
507215  TNFSF10; tumor necrosis factor ligand superfamily member 10 [KO:K04721]
784541  tumor necrosis factor receptor superfamily member 10A isoform X1 [KO:K04722]
104968444  tumor necrosis factor receptor superfamily member 10C [KO:K04722]
407111  FASLG; tumor necrosis factor ligand superfamily member 6 [KO:K04389]
282488  FAS; tumor necrosis factor receptor superfamily member 6 precursor [KO:K04390]
282527  TNFRSF1A; tumor necrosis factor receptor superfamily member 1A precursor [KO:K03158]
504707  TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein [KO:K03171]
493720  FADD; FAS-associated death domain protein [KO:K02373]
507481  CASP8; caspase-8 [KO:K04398] [EC:3.4.22.61]
510373  BID; BH3-interacting domain death agonist [KO:K04726]
280730  BAX; apoptosis regulator BAX [KO:K02159]
514090  BAK1; bcl-2 homologous antagonist/killer [KO:K14021]
282119  VDAC1; voltage-dependent anion-selective channel protein 1 [KO:K05862]
282478  SLC25A4; ADP/ATP translocase 1 [KO:K05863]
282479  SLC25A5; ADP/ATP translocase 2 [KO:K05863]
282480  SLC25A6; ADP/ATP translocase 3 [KO:K05863]
541168  SLC25A31; ADP/ATP translocase 4 [KO:K05863]
787122  ADP/ATP translocase 1 [KO:K05863]
132344463  ADP/ATP translocase 3 [KO:K05863]
510767  CYCS; cytochrome c [KO:K08738]
781996  CYCT; cytochrome c 2 [KO:K08738]
100847700  cytochrome c [KO:K08738]
100847304  cytochrome c-like [KO:K08738]
112447733  cytochrome c-like [KO:K08738]
537782  APAF1; apoptotic protease-activating factor 1 [KO:K02084]
100140945  CASP9; caspase-9 [KO:K04399] [EC:3.4.22.62]
408016  CASP3; caspase-3 [KO:K02187] [EC:3.4.22.56]
280875  CPSF4; cleavage and polyadenylation specificity factor subunit 4 [KO:K14404]
790056  CPSF4L; LOW QUALITY PROTEIN: putative cleavage and polyadenylation specificity factor subunit 4-like protein [KO:K14404]
282298  PABPN1; polyadenylate-binding protein 2 [KO:K14396]
617429  PABPN1L; LOW QUALITY PROTEIN: embryonic polyadenylate-binding protein 2 [KO:K14396]
616281  polyadenylate-binding protein 2-like [KO:K14396]
112442288  polyadenylate-binding protein 2-like [KO:K14396]
512136  NXF1; nuclear RNA export factor 1 [KO:K14284]
613789  NXF2; nuclear RNA export factor 2 [KO:K14284]
615581  nuclear RNA export factor 3 isoform X1 [KO:K14284]
785244  LOW QUALITY PROTEIN: nuclear RNA export factor 3 [KO:K14284]
523530  NXF3; nuclear RNA export factor 3 isoform X1 [KO:K14284]
132344734  nuclear RNA export factor 3-like [KO:K14284]
520351  NXT1; NTF2-related export protein 1 [KO:K14285]
513043  NXT2; NTF2-related export protein 2 [KO:K14285]
533197  HNRNPUL1; heterogeneous nuclear ribonucleoprotein U-like protein 1 [KO:K15047]
513080  RAE1; mRNA export factor [KO:K14298]
540004  NUP98; nuclear pore complex protein Nup98-Nup96 isoform X2 [KO:K14297]
506415  RSAD2; S-adenosylmethionine-dependent nucleotide dehydratase RSAD2 precursor [KO:K15045]
281156  FDPS; farnesyl pyrophosphate synthase [KO:K00787] [EC:2.5.1.1 2.5.1.10]
282001  PRKCA; protein kinase C alpha type [KO:K02677] [EC:2.7.11.13]
521196  RAF1; RAF proto-oncogene serine/threonine-protein kinase [KO:K04366] [EC:2.7.11.1]
533199  MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 [KO:K04368] [EC:2.7.12.2]
101905399  LOW QUALITY PROTEIN: dual specificity mitogen-activated protein kinase kinase 1-like [KO:K04368] [EC:2.7.12.2]
510434  MAP2K2; dual specificity mitogen-activated protein kinase kinase 2 [KO:K04369] [EC:2.7.12.2]
327672  MAPK1; mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
531391  MAPK3; mitogen-activated protein kinase 3 [KO:K04371] [EC:2.7.11.24]
404122  ACTG1; actin, cytoplasmic 2 [KO:K05692]
280979  ACTB; actin, cytoplasmic 1 [KO:K05692]
534708  RAB11A; ras-related protein Rab-11A [KO:K07904]
532723  RAB11B; ras-related protein Rab-11B [KO:K07905]
510568  XPO1; exportin-1 [KO:K14290]
539679  KPNA1; importin subunit alpha-5 [KO:K23940]
513592  KPNA2; importin subunit alpha-1 [KO:K15043]
789280  KPNA7; importin subunit alpha-8 [KO:K15043]
531602  KPNA6; importin subunit alpha-7 [KO:K15042]
783596  KPNA5; importin subunit alpha-6 [KO:K15042]
Compound
C00027  Hydrogen peroxide
C00080  H+
C05981  Phosphatidylinositol-3,4,5-trisphosphate
Reference
PMID:24225499
  Authors
Edinger TO, Pohl MO, Stertz S
  Title
Entry of influenza A virus: host factors and antiviral targets.
  Journal
J Gen Virol 95:263-77 (2014)
DOI:10.1099/vir.0.059477-0
Reference
PMID:19565019
  Authors
Kido H, Okumura Y, Takahashi E, Pan HY, Wang S, Chida J, Le TQ, Yano M
  Title
Host envelope glycoprotein processing proteases are indispensable for entry into human cells by seasonal and highly pathogenic avian influenza viruses.
  Journal
J Mol Genet Med 3:167-75 (2008)
Reference
PMID:27751627
  Authors
Ramakrishnan B, Viswanathan K, Tharakaraman K, Dancik V, Raman R, Babcock GJ, Shriver Z, Sasisekharan R
  Title
A Structural and Mathematical Modeling Analysis of the Likelihood of Antibody-Dependent Enhancement in Influenza.
  Journal
Trends Microbiol 24:933-943 (2016)
DOI:10.1016/j.tim.2016.09.003
Reference
PMID:18588994
  Authors
Thanh TT, van Doorn HR, de Jong MD
  Title
Human H5N1 influenza: current insight into pathogenesis.
  Journal
Int J Biochem Cell Biol 40:2671-4 (2008)
DOI:10.1016/j.biocel.2008.05.019
Reference
PMID:23977434
  Authors
Michael P, Brabant D, Bleiblo F, Ramana CV, Rutherford M, Khurana S, Tai TC, Kumar A, Kumar A
  Title
Influenza A induced cellular signal transduction pathways.
  Journal
J Thorac Dis 5 Suppl 2:S132-41 (2013)
DOI:10.3978/j.issn.2072-1439.2013.07.42
Reference
PMID:20020828
  Authors
Hale BG, Albrecht RA, Garcia-Sastre A
  Title
Innate immune evasion strategies of influenza viruses.
  Journal
Future Microbiol 5:23-41 (2010)
DOI:10.2217/fmb.09.108
Reference
PMID:21698289
  Authors
Sharma K, Tripathi S, Ranjan P, Kumar P, Garten R, Deyde V, Katz JM, Cox NJ, Lal RB, Sambhara S, Lal SK
  Title
Influenza A virus nucleoprotein exploits Hsp40 to inhibit PKR activation.
  Journal
PLoS One 6:e20215 (2011)
DOI:10.1371/journal.pone.0020215
Reference
PMID:19782761
  Authors
Ehrhardt C, Seyer R, Hrincius ER, Eierhoff T, Wolff T, Ludwig S
  Title
Interplay between influenza A virus and the innate immune signaling.
  Journal
Microbes Infect 12:81-7 (2010)
DOI:10.1016/j.micinf.2009.09.007
Reference
PMID:23170167
  Authors
van de Sandt CE, Kreijtz JH, Rimmelzwaan GF
  Title
Evasion of influenza A viruses from innate and adaptive immune responses.
  Journal
Viruses 4:1438-76 (2012)
DOI:10.3390/v4091438
Reference
PMID:30487536
  Authors
Long JS, Mistry B, Haslam SM, Barclay WS
  Title
Host and viral determinants of influenza A virus species specificity.
  Journal
Nat Rev Microbiol 17:67-81 (2019)
DOI:10.1038/s41579-018-0115-z
Reference
PMID:29556226
  Authors
Chen X, Liu S, Goraya MU, Maarouf M, Huang S, Chen JL
  Title
Host Immune Response to Influenza A Virus Infection.
  Journal
Front Immunol 9:320 (2018)
DOI:10.3389/fimmu.2018.00320
Reference
PMID:20130137
  Authors
Lu X, Masic A, Li Y, Shin Y, Liu Q, Zhou Y
  Title
The PI3K/Akt pathway inhibits influenza A virus-induced Bax-mediated apoptosis by negatively regulating the JNK pathway via ASK1.
  Journal
J Gen Virol 91:1439-49 (2010)
DOI:10.1099/vir.0.018465-0
Reference
PMID:18980544
  Authors
Ichinohe T, Iwasaki A, Hasegawa H
  Title
Innate sensors of influenza virus: clues to developing better intranasal vaccines.
  Journal
Expert Rev Vaccines 7:1435-45 (2008)
DOI:10.1586/14760584.7.9.1435
Reference
PMID:27231932
  Authors
Le Sage V, Cinti A, Amorim R, Mouland AJ
  Title
Adapting the Stress Response: Viral Subversion of the mTOR Signaling Pathway.
  Journal
Viruses 8:E152 (2016)
DOI:10.3390/v8060152
Reference
PMID:30510918
  Authors
Fan Y, Sanyal S, Bruzzone R
  Title
Breaking Bad: How Viruses Subvert the Cell Cycle.
  Journal
Front Cell Infect Microbiol 8:396 (2018)
DOI:10.3389/fcimb.2018.00396
Reference
PMID:21971186
  Authors
Varga ZT, Palese P
  Title
The influenza A virus protein PB1-F2: killing two birds with one stone?
  Journal
Virulence 2:542-6 (2011)
DOI:10.4161/viru.2.6.17812
Reference
PMID:30254192
  Authors
Atkin-Smith GK, Duan M, Chen W, Poon IKH
  Title
The induction and consequences of Influenza A virus-induced cell death.
  Journal
Cell Death Dis 9:1002 (2018)
DOI:10.1038/s41419-018-1035-6
Reference
PMID:30545063
  Authors
Nogales A, Martinez-Sobrido L, Topham DJ, DeDiego ML
  Title
Modulation of Innate Immune Responses by the Influenza A NS1 and PA-X Proteins.
  Journal
Viruses 10:E708 (2018)
DOI:10.3390/v10120708
Reference
PMID:21253874
  Authors
Dai X, Zhang L, Hong T
  Title
Host cellular signaling induced by influenza virus.
  Journal
Sci China Life Sci 54:68-74 (2011)
DOI:10.1007/s11427-010-4116-z
Reference
PMID:26008706
  Authors
Li J, Yu M, Zheng W, Liu W
  Title
Nucleocytoplasmic shuttling of influenza A virus proteins.
  Journal
Viruses 7:2668-82 (2015)
DOI:10.3390/v7052668
Reference
PMID:30079062
  Authors
Dou D, Revol R, Ostbye H, Wang H, Daniels R
  Title
Influenza A Virus Cell Entry, Replication, Virion Assembly and Movement.
  Journal
Front Immunol 9:1581 (2018)
DOI:10.3389/fimmu.2018.01581
Reference
PMID:23236273
  Authors
Paterson D, Fodor E
  Title
Emerging roles for the influenza A virus nuclear export protein (NEP).
  Journal
PLoS Pathog 8:e1003019 (2012)
DOI:10.1371/journal.ppat.1003019
Related
pathway
bta00900  Terpenoid backbone biosynthesis
bta03013  Nucleocytoplasmic transport
bta03015  mRNA surveillance pathway
bta04010  MAPK signaling pathway
bta04110  Cell cycle
bta04144  Endocytosis
bta04210  Apoptosis
bta04620  Toll-like receptor signaling pathway
bta04621  NOD-like receptor signaling pathway
bta04622  RIG-I-like receptor signaling pathway
bta04630  JAK-STAT signaling pathway
bta05416  Viral myocarditis
KO pathway
ko05164   
LinkDB

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