KEGG   PATHWAY: lcat05169
Entry
lcat05169                   Pathway                                
Name
Epstein-Barr virus infection - Lemur catta (Ring-tailed lemur)
Description
Epstein-Barr virus (EBV) is a gamma-herpes virus that widely infects human populations predominantly at an early age but remains mostly asymptomatic. EBV has been linked to a wide spectrum of human malignancies, including nasopharyngeal carcinoma and other hematologic cancers, like Hodgkin's lymphoma, Burkitt's lymphoma (BL), B-cell immunoblastic lymphoma in HIV patients, and posttransplant-associated lymphoproliferative diseases.  EBV has the unique ability to establish life-long latent infection in primary human B lymphocytes. During latent infection, EBV expresses a small subset of genes, including 6 nuclear antigens (EBNA-1, -2, -3A, -3B, -3C, and -LP), 3 latent membrane proteins (LMP-1, -2A, and -2B), 2 small noncoding RNAs (EBER-1 and 2). On the basis of these latent gene expression, three different latency patterns associated with the types of cancers are recognized.
Class
Human Diseases; Infectious disease: viral
Pathway map
lcat05169  Epstein-Barr virus infection
lcat05169

Organism
Lemur catta (Ring-tailed lemur) [GN:lcat]
Gene
123626891  CR2; complement receptor type 2 [KO:K04012]
123632520  CD19; B-lymphocyte antigen CD19 isoform X1 [KO:K06465]
123631796  mamu class II histocompatibility antigen, DR alpha chain [KO:K06752]
123631797  HLA class II histocompatibility antigen, DRB1 beta chain-like [KO:K06752]
123631798  HLA class II histocompatibility antigen, DQ alpha 2 chain [KO:K06752]
123631799  HLA class II histocompatibility antigen, DQ beta 1 chain-like [KO:K06752]
123631804  HLA class II histocompatibility antigen, DO beta chain isoform X1 [KO:K06752]
123631807  HLA class II histocompatibility antigen, DM beta chain [KO:K06752]
123631808  HLA class II histocompatibility antigen, DM alpha chain isoform X1 [KO:K06752]
123631809  HLA class II histocompatibility antigen, DO alpha chain isoform X1 [KO:K06752]
123631812  HLA class II histocompatibility antigen, DP alpha 1 chain isoform X1 [KO:K06752]
123631813  HLA class II histocompatibility antigen, DP beta 1 chain-like isoform X1 [KO:K06752]
123631814  HLA class II histocompatibility antigen, DP beta 1 chain [KO:K06752]
123638501  TLR2; toll-like receptor 2 [KO:K10159]
123627174  MYD88; myeloid differentiation primary response protein MyD88 [KO:K04729]
123639836  IRAK4; interleukin-1 receptor-associated kinase 4 isoform X1 [KO:K04733] [EC:2.7.11.1]
123628474  IRAK1; interleukin-1 receptor-associated kinase 1 [KO:K04730] [EC:2.7.11.1]
123642600  TRAF6; TNF receptor-associated factor 6 [KO:K03175] [EC:2.3.2.27]
123640344  TAB1; TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 [KO:K04403]
123633357  TAB2; TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 [KO:K04404]
123633076  MAP3K7; mitogen-activated protein kinase kinase kinase 7 isoform X1 [KO:K04427] [EC:2.7.11.25]
123650134  CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1 [KO:K04467] [EC:2.7.11.10]
123626609  IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1 [KO:K07209] [EC:2.7.11.10]
123628501  IKBKG; NF-kappa-B essential modulator isoform X1 [KO:K07210]
123650127  NFKBIA; NF-kappa-B inhibitor alpha [KO:K04734]
123627206  NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1 [KO:K02580]
123641353  RELA; transcription factor p65 isoform X1 [KO:K04735]
123631724  TNF; tumor necrosis factor [KO:K03156]
123646908  IL6; interleukin-6 [KO:K05405]
123646234  DDX58; antiviral innate immune response receptor RIG-I [KO:K12646] [EC:5.6.2.6]
123622556  MAVS; mitochondrial antiviral-signaling protein isoform X1 [KO:K12648]
123644162  TRAF3; TNF receptor-associated factor 3 isoform X1 [KO:K03174]
123639558  TBK1; serine/threonine-protein kinase TBK1 isoform X1 [KO:K05410] [EC:2.7.11.10]
123627128  IKBKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform X1 [KO:K07211] [EC:2.7.11.10]
123642940  IRF7; interferon regulatory factor 7 isoform X1 [KO:K09447]
123623813  IRF3; interferon regulatory factor 3 isoform X1 [KO:K05411]
123645632  interferon alpha-5-like [KO:K05414]
123645638  interferon alpha-10-like [KO:K05414]
123645752  interferon alpha-5-like [KO:K05414]
123645754  interferon alpha-5-like [KO:K05414]
123645755  interferon alpha-5-like [KO:K05414]
123645758  interferon alpha-10-like [KO:K05414]
123646712  interferon alpha-5-like [KO:K05414]
123646249  IFNB1; interferon beta [KO:K05415]
123630696  IFNAR1; interferon alpha/beta receptor 1 [KO:K05130]
123630694  IFNAR2; interferon alpha/beta receptor 2 isoform X1 [KO:K05131]
123635562  JAK1; tyrosine-protein kinase JAK1 [KO:K11217] [EC:2.7.10.2]
123634210  TYK2; non-receptor tyrosine-protein kinase TYK2 isoform X1 [KO:K11219] [EC:2.7.10.2]
123643619  STAT1; signal transducer and activator of transcription 1-alpha/beta [KO:K11220]
123639648  STAT2; signal transducer and activator of transcription 2 [KO:K11221]
123650803  IRF9; interferon regulatory factor 9 [KO:K04693]
123636797  EIF2AK2; interferon-induced, double-stranded RNA-activated protein kinase isoform X1 [KO:K16195] [EC:2.7.11.1]
123625980  OAS3; 2'-5'-oligoadenylate synthase 3 [KO:K14216] [EC:2.7.7.84]
123626026  OAS2; 2'-5'-oligoadenylate synthase 2 [KO:K14216] [EC:2.7.7.84]
123626027  OAS1; 2'-5'-oligoadenylate synthase 1 [KO:K14216] [EC:2.7.7.84]
123624739  CXCL10; C-X-C motif chemokine 10 [KO:K12671]
123636037  ISG15; ubiquitin-like protein ISG15 [KO:K12159]
123649928  FAS; tumor necrosis factor receptor superfamily member 6 isoform X1 [KO:K04390]
123642797  FADD; FAS-associated death domain protein [KO:K02373]
123643895  CASP8; caspase-8 isoform X1 [KO:K04398] [EC:3.4.22.61]
123640175  BID; BH3-interacting domain death agonist [KO:K04726]
123637184  BCL2L11; bcl-2-like protein 11 isoform X1 [KO:K16341]
123621883  BCL2; apoptosis regulator Bcl-2 [KO:K02161]
123623846  BAX; apoptosis regulator BAX isoform X1 [KO:K02159]
123632819  BAK1; bcl-2 homologous antagonist/killer [KO:K14021]
123638028  cytochrome c-like [KO:K08738]
123645426  cytochrome c-like [KO:K08738]
123638197  cytochrome c-like [KO:K08738]
123639916  cytochrome c, somatic-like [KO:K08738]
123647359  cytochrome c, somatic [KO:K08738]
123650585  cytochrome c-like [KO:K08738]
123620171  cytochrome c, somatic-like [KO:K08738]
123643690  cytochrome c 2 [KO:K08738]
123639404  APAF1; apoptotic protease-activating factor 1 isoform X1 [KO:K02084]
123635958  CASP9; caspase-9 isoform X1 [KO:K04399] [EC:3.4.22.62]
123638644  CASP3; caspase-3 isoform X1 [KO:K02187] [EC:3.4.22.56]
123641521  CD3E; T-cell surface glycoprotein CD3 epsilon chain isoform X1 [KO:K06451]
123641519  CD3G; T-cell surface glycoprotein CD3 gamma chain [KO:K06452]
123641520  CD3D; T-cell surface glycoprotein CD3 delta chain isoform X1 [KO:K06450]
123634942  CD247; T-cell surface glycoprotein CD3 zeta chain isoform X1 [KO:K06453]
123647075  PSMC2; 26S proteasome regulatory subunit 7 [KO:K03061]
123645645  PSMC1; 26S proteasome regulatory subunit 4 [KO:K03062]
123624327  PSMC4; 26S proteasome regulatory subunit 6B [KO:K03063]
123649129  PSMC6; 26S proteasome regulatory subunit 10B [KO:K03064]
123642678  PSMC3; LOW QUALITY PROTEIN: 26S proteasome regulatory subunit 6A [KO:K03065]
123620597  PSMC5; 26S proteasome regulatory subunit 8 isoform X1 [KO:K03066]
123630330  PSMD2; 26S proteasome non-ATPase regulatory subunit 2 [KO:K03028]
123643857  PSMD1; 26S proteasome non-ATPase regulatory subunit 1 [KO:K03032]
123620852  PSMD3; 26S proteasome non-ATPase regulatory subunit 3 [KO:K03033]
123650594  PSMD12; 26S proteasome non-ATPase regulatory subunit 12 [KO:K03035]
123620321  PSMD11; 26S proteasome non-ATPase regulatory subunit 11 [KO:K03036]
123623513  PSMD6; 26S proteasome non-ATPase regulatory subunit 6 [KO:K03037]
123625148  PSMD7; 26S proteasome non-ATPase regulatory subunit 7 [KO:K03038]
123642988  PSMD13; 26S proteasome non-ATPase regulatory subunit 13 [KO:K03039]
123633966  PSMD4; 26S proteasome non-ATPase regulatory subunit 4 isoform X1 [KO:K03029]
123643962  PSMD14; 26S proteasome non-ATPase regulatory subunit 14 [KO:K03030]
123624378  PSMD8; 26S proteasome non-ATPase regulatory subunit 8 [KO:K03031]
123622513  ADRM1; proteasomal ubiquitin receptor ADRM1 isoform X1 [KO:K06691]
123646853  SEM1; 26S proteasome complex subunit SEM1 isoform X1 [KO:K10881]
123631801  TAP1; antigen peptide transporter 1 [KO:K05653] [EC:7.4.2.14]
123631802  TAP2; antigen peptide transporter 2 [KO:K05654] [EC:7.4.2.14]
123631829  tapasin isoform X1 [KO:K08058]
123630535  PDIA3; protein disulfide-isomerase A3 [KO:K08056] [EC:5.3.4.1]
123636809  LOW QUALITY PROTEIN: calreticulin-like [KO:K08057]
123637304  CALR; calreticulin [KO:K08057]
123631673  class I histocompatibility antigen, Gogo-B*0102 alpha chain-like isoform X1 [KO:K06751]
123631675  patr class I histocompatibility antigen, B-2 alpha chain-like isoform X1 [KO:K06751]
123631677  patr class I histocompatibility antigen, A-2 alpha chain-like [KO:K06751]
123631716  HLA class I histocompatibility antigen, alpha chain G-like isoform X1 [KO:K06751]
123622080  B2M; beta-2-microglobulin [KO:K08055]
123646032  SNW1; SNW domain-containing protein 1 isoform X1 [KO:K06063]
123624516  SIN3A; paired amphipathic helix protein Sin3a [KO:K11644]
123630240  histone deacetylase 1-like [KO:K06067] [EC:3.5.1.98]
123633182  HDAC2; histone deacetylase 2 [KO:K06067] [EC:3.5.1.98]
123634666  LOW QUALITY PROTEIN: histone deacetylase 1-like [KO:K06067] [EC:3.5.1.98]
123635833  HDAC1; histone deacetylase 1 [KO:K06067] [EC:3.5.1.98]
123626136  NCOR2; nuclear receptor corepressor 2 isoform X1 [KO:K06065]
123638038  SAP30L; histone deacetylase complex subunit SAP30L [KO:K19202]
123638689  SAP30; histone deacetylase complex subunit SAP30 [KO:K19202]
123643416  CIR1; corepressor interacting with RBPJ 1 [KO:K06066]
123637349  RBPJ; recombining binding protein suppressor of hairless isoform X1 [KO:K06053]
123622623  RBPJL; recombining binding protein suppressor of hairless-like protein [KO:K06053]
123630402  HES1; transcription factor HES-1 [KO:K06054]
123635397  FCER2; low affinity immunoglobulin epsilon Fc receptor [KO:K06468]
123634397  RUNX3; runt-related transcription factor 3 [KO:K09279]
123644625  MYC; myc proto-oncogene protein [KO:K04377]
123632364  USP7; ubiquitin carboxyl-terminal hydrolase 7 isoform X1 [KO:K11838] [EC:3.4.19.12]
123639534  MDM2; E3 ubiquitin-protein ligase Mdm2 isoform X1 [KO:K06643] [EC:2.3.2.27]
123627975  E3 ubiquitin-protein ligase Mdm2-like [KO:K06643] [EC:2.3.2.27]
123650900  TP53; cellular tumor antigen p53 [KO:K04451]
123632883  CDKN1A; cyclin-dependent kinase inhibitor 1 [KO:K06625]
123645865  GADD45G; growth arrest and DNA damage-inducible protein GADD45 gamma [KO:K04402]
123633177  GADD45B; growth arrest and DNA damage-inducible protein GADD45 beta isoform X1 [KO:K04402]
123635537  GADD45A; growth arrest and DNA damage-inducible protein GADD45 alpha [KO:K04402]
123642672  DDB2; DNA damage-binding protein 2 isoform X1 [KO:K10140]
123648554  POLK; DNA polymerase kappa isoform X1 [KO:K03511] [EC:2.7.7.7]
123627059  TRAF5; TNF receptor-associated factor 5 isoform X1 [KO:K09849]
123629856  PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
123630278  PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
123634506  PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform [KO:K00922] [EC:2.7.1.153]
123639706  PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta [KO:K02649]
123648578  PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
123634187  phosphatidylinositol 3-kinase regulatory subunit gamma [KO:K02649]
123624322  AKT2; RAC-beta serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
123627566  AKT3; RAC-gamma serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
123643797  AKT1; RAC-alpha serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
123621038  MAP3K14; mitogen-activated protein kinase kinase kinase 14 isoform X1 [KO:K04466] [EC:2.7.11.25]
123623971  RELB; transcription factor RelB isoform X1 [KO:K09253]
123650084  NFKB2; nuclear factor NF-kappa-B p100 subunit isoform X1 [KO:K04469]
123625188  TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein isoform X1 [KO:K03171]
123624357  NFKBIB; NF-kappa-B inhibitor beta [KO:K02581]
123631937  NFKBIE; NF-kappa-B inhibitor epsilon isoform X1 [KO:K05872]
123621224  MAP2K4; dual specificity mitogen-activated protein kinase kinase 4 isoform X1 [KO:K04430] [EC:2.7.12.2]
123635482  MAP2K7; dual specificity mitogen-activated protein kinase kinase 7 isoform X1 [KO:K04431] [EC:2.7.12.2]
123621799  MAPK9; mitogen-activated protein kinase 9 isoform X1 [KO:K04440] [EC:2.7.11.24]
123650465  MAPK8; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
123627295  MAPK10; mitogen-activated protein kinase 10 isoform X1 [KO:K04440] [EC:2.7.11.24]
123645603  TRAF2; TNF receptor-associated factor 2 isoform X1 [KO:K03173] [EC:2.3.2.27]
123638176  RIPK1; receptor-interacting serine/threonine-protein kinase 1 isoform X1 [KO:K02861] [EC:2.7.11.1]
123650554  MAP2K3; dual specificity mitogen-activated protein kinase kinase 3 isoform X1 [KO:K04432] [EC:2.7.12.2]
123650624  MAP2K6; dual specificity mitogen-activated protein kinase kinase 6 [KO:K04433] [EC:2.7.12.2]
123632869  MAPK14; mitogen-activated protein kinase 14 isoform X1 [KO:K04441] [EC:2.7.11.24]
123632871  MAPK13; mitogen-activated protein kinase 13 [KO:K04441] [EC:2.7.11.24]
123640770  MAPK12; mitogen-activated protein kinase 12 [KO:K04441] [EC:2.7.11.24]
123640771  MAPK11; mitogen-activated protein kinase 11 isoform X1 [KO:K04441] [EC:2.7.11.24]
123635592  JUN; transcription factor AP-1 [KO:K04448]
123646125  ENTPD8; ectonucleoside triphosphate diphosphohydrolase 8 [KO:K01510] [EC:3.6.1.5]
123623415  ENTPD3; ectonucleoside triphosphate diphosphohydrolase 3 isoform X1 [KO:K01510] [EC:3.6.1.5]
123649686  ENTPD1; ectonucleoside triphosphate diphosphohydrolase 1 isoform X1 [KO:K01510] [EC:3.6.1.5]
123622328  CD40; tumor necrosis factor receptor superfamily member 5 isoform X1 [KO:K03160]
123642590  CD44; CD44 antigen isoform X1 [KO:K06256]
123632733  ITGAL; integrin alpha-L isoform X1 [KO:K05718]
123635100  CD58; lymphocyte function-associated antigen 3 isoform X1 [KO:K06492]
123634153  ICAM1; intercellular adhesion molecule 1 [KO:K06490]
123625662  VIM; vimentin [KO:K07606]
123633309  TNFAIP3; tumor necrosis factor alpha-induced protein 3 [KO:K11859] [EC:3.4.19.12]
123639564  JAK3; tyrosine-protein kinase JAK3 isoform X1 [KO:K11218] [EC:2.7.10.2]
123620960  STAT3; signal transducer and activator of transcription 3 isoform X1 [KO:K04692]
123644610  LYN; tyrosine-protein kinase Lyn isoform X1 [KO:K05854] [EC:2.7.10.2]
123646461  SYK; tyrosine-protein kinase SYK isoform X1 [KO:K05855] [EC:2.7.10.2]
123623075  NEDD4; E3 ubiquitin-protein ligase NEDD4 isoform X1 [KO:K10591] [EC:2.3.2.26]
123631548  RAC1; ras-related C3 botulinum toxin substrate 1 [KO:K04392]
123643379  LOW QUALITY PROTEIN: uncharacterized protein LOC123643379 [KO:K06856]
123643441  immunoglobulin gamma-1 heavy chain-like [KO:K06856]
123643449  immunoglobulin delta heavy chain-like [KO:K06856]
123643456  immunoglobulin epsilon heavy chain-like [KO:K06856]
123643464  uncharacterized protein LOC123643464 [KO:K06856]
123649775  BLNK; B-cell linker protein isoform X1 [KO:K07371]
123625473  PLCG2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 [KO:K05859] [EC:3.1.4.11]
123648646  SKP2; S-phase kinase-associated protein 2 [KO:K03875]
123639989  CDKN1B; cyclin-dependent kinase inhibitor 1B [KO:K06624]
123642799  CCND1; G1/S-specific cyclin-D1 isoform X1 [KO:K04503]
123640152  CCND2; G1/S-specific cyclin-D2 [KO:K10151]
123631868  CCND3; G1/S-specific cyclin-D3 isoform X1 [KO:K10152]
123639589  CDK4; cyclin-dependent kinase 4 [KO:K02089] [EC:2.7.11.22]
123647595  CDK6; cyclin-dependent kinase 6 isoform X1 [KO:K02091] [EC:2.7.11.22]
123638601  CCNA2; cyclin-A2 [KO:K06627]
123649215  CCNA1; cyclin-A1 isoform X1 [KO:K06627]
123644579  CCNE2; G1/S-specific cyclin-E2 isoform X1 [KO:K06626]
123624519  CCNE1; G1/S-specific cyclin-E1 isoform X1 [KO:K06626]
123639673  CDK2; cyclin-dependent kinase 2 isoform X1 [KO:K02206] [EC:2.7.11.22]
123649357  RB1; retinoblastoma-associated protein isoform X1 [KO:K06618]
123622430  E2F1; transcription factor E2F1 isoform X1 [KO:K17454]
123634427  E2F2; transcription factor E2F2 isoform X1 [KO:K09389]
123638325  E2F3; transcription factor E2F3 isoform X1 [KO:K06620]
Compound
C00076  Calcium cation
C01245  D-myo-Inositol 1,4,5-trisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
Reference
PMID:15510157
  Authors
Young LS, Rickinson AB.
  Title
Epstein-Barr virus: 40 years on.
  Journal
Nat Rev Cancer 4:757-68 (2004)
DOI:10.1038/nrc1452
Reference
PMID:21372216
  Authors
Saha A, Robertson ES
  Title
Epstein-Barr virus-associated B-cell lymphomas: pathogenesis and clinical outcomes.
  Journal
Clin Cancer Res 17:3056-63 (2011)
DOI:10.1158/1078-0432.CCR-10-2578
Reference
PMID:21429244
  Authors
Ning S
  Title
Innate immune modulation in EBV infection.
  Journal
Herpesviridae 2:1 (2011)
DOI:10.1186/2042-4280-2-1
Reference
PMID:28408983
  Authors
Stanfield BA, Luftig MA
  Title
Recent advances in understanding Epstein-Barr virus.
  Journal
F1000Res 6:386 (2017)
DOI:10.12688/f1000research.10591.1
Reference
PMID:24586164
  Authors
van Gent M, Braem SG, de Jong A, Delagic N, Peeters JG, Boer IG, Moynagh PN, Kremmer E, Wiertz EJ, Ovaa H, Griffin BD, Ressing ME
  Title
Epstein-Barr virus large tegument protein BPLF1 contributes to innate immune evasion through interference with toll-like receptor signaling.
  Journal
PLoS Pathog 10:e1003960 (2014)
DOI:10.1371/journal.ppat.1003960
Reference
PMID:23850008
  Authors
Rajsbaum R, Garcia-Sastre A
  Title
Viral evasion mechanisms of early antiviral responses involving regulation of ubiquitin pathways.
  Journal
Trends Microbiol 21:421-9 (2013)
DOI:10.1016/j.tim.2013.06.006
Reference
PMID:25704559
  Authors
Hoffmann HH, Schneider WM, Rice CM
  Title
Interferons and viruses: an evolutionary arms race of molecular interactions.
  Journal
Trends Immunol 36:124-38 (2015)
DOI:10.1016/j.it.2015.01.004
Reference
PMID:22110506
  Authors
Spender LC, Inman GJ
  Title
Inhibition of germinal centre apoptotic programmes by epstein-barr virus.
  Journal
Adv Hematol 2011:829525 (2011)
DOI:10.1155/2011/829525
Reference
PMID:23303627
  Authors
Fu Q, He C, Mao ZR
  Title
Epstein-Barr virus interactions with the Bcl-2 protein family and apoptosis in human tumor cells.
  Journal
J Zhejiang Univ Sci B 14:8-24 (2013)
DOI:10.1631/jzus.B1200189
Reference
PMID:29116588
  Authors
Wang Y, Banerjee S, Ding L, Cai C, Wei F, Cai Q
  Title
The regulatory role of protein phosphorylation in human gammaherpesvirus associated cancers.
  Journal
Virol Sin 32:357-368 (2017)
DOI:10.1007/s12250-017-4081-9
Reference
PMID:23435233
  Authors
Melchjorsen J
  Title
Learning from the messengers: innate sensing of viruses and cytokine regulation of immunity - clues for treatments and vaccines.
  Journal
Viruses 5:470-527 (2013)
DOI:10.3390/v5020470
Reference
PMID:19498380
  Authors
Hansen TH, Bouvier M
  Title
MHC class I antigen presentation: learning from viral evasion strategies.
  Journal
Nat Rev Immunol 9:503-13 (2009)
DOI:10.1038/nri2575
Reference
PMID:18977445
  Authors
Ressing ME, Horst D, Griffin BD, Tellam J, Zuo J, Khanna R, Rowe M, Wiertz EJ
  Title
Epstein-Barr virus evasion of CD8(+) and CD4(+) T cell immunity via concerted actions of multiple gene products.
  Journal
Semin Cancer Biol 18:397-408 (2008)
DOI:10.1016/j.semcancer.2008.10.008
Reference
PMID:21146386
  Authors
Horst D, Verweij MC, Davison AJ, Ressing ME, Wiertz EJ
  Title
Viral evasion of T cell immunity: ancient mechanisms offering new applications.
  Journal
Curr Opin Immunol 23:96-103 (2011)
DOI:10.1016/j.coi.2010.11.005
Reference
PMID:27886133
  Authors
Ghosh Roy S, Robertson ES, Saha A
  Title
Epigenetic Impact on EBV Associated B-Cell Lymphomagenesis.
  Journal
Biomolecules 6:E46 (2016)
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Related
pathway
lcat03050  Proteasome
lcat04010  MAPK signaling pathway
lcat04020  Calcium signaling pathway
lcat04064  NF-kappa B signaling pathway
lcat04110  Cell cycle
lcat04115  p53 signaling pathway
lcat04210  Apoptosis
lcat04612  Antigen processing and presentation
lcat04620  Toll-like receptor signaling pathway
lcat04622  RIG-I-like receptor signaling pathway
lcat04630  JAK-STAT signaling pathway
lcat04662  B cell receptor signaling pathway
KO pathway
ko05169   
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