KEGG   PATHWAY: mcc05167
Entry
mcc05167                    Pathway                                
Name
Kaposi sarcoma-associated herpesvirus infection - Macaca mulatta (rhesus monkey)
Description
Kaposi sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus 8 (HHV-8), is the most recently identified human tumor virus, and is associated with the pathogenesis of Kaposi's sarcoma (KS), primary effusion lymphoma (PEL), and Multicentric Castleman's disease (MCD). Like all other herpesviruses, KSHV displays two modes of life cycle, latency and lytic replication, which are characterized by the patterns of viral gene expression. Genes expressed in latency (LANA, v-cyclin, v-FLIP, Kaposins A, B and C and viral miRNAs) are mainly thought to facilitate the establishment of life long latency in its host and survival against the host innate, and adaptive immune surveillance mechanisms. Among the viral proteins shown to be expressed during lytic replication are potent signaling molecules such as vGPCR, vIL6, vIRFs, vCCLs, K1 and K15, which have been implicated experimentally in the angiogenic and inflammatory phenotype observed in KS lesions. Several of these latent viral and lytic proteins are known to transform host cells, linking KSHV with the development of severe human malignancies.
Class
Human Diseases; Infectious disease: viral
Pathway map
mcc05167  Kaposi sarcoma-associated herpesvirus infection
mcc05167

Organism
Macaca mulatta (rhesus monkey) [GN:mcc]
Gene
703613  C3; complement C3 [KO:K03990]
574378  TLR3; toll-like receptor 3 precursor [KO:K05401]
574294  TICAM1; TIR domain-containing adapter molecule 1 [KO:K05842]
693961  TRAF3; TNF receptor-associated factor 3 isoform X1 [KO:K03174]
695607  IKBKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [KO:K07211] [EC:2.7.11.10]
717427  TBK1; serine/threonine-protein kinase TBK1 [KO:K05410] [EC:2.7.11.10]
699578  IRF7; interferon regulatory factor 7 [KO:K09447]
709948  IFNA2; interferon alpha-2 precursor [KO:K05414]
709755  IFNA8; interferon alpha-8 [KO:K05414]
710751  interferon alpha-17-like [KO:K05414]
694631  interferon alpha-1/13-like [KO:K05414]
710487  interferon alpha-14 [KO:K05414]
710528  interferon alpha-1/13 [KO:K05414]
710568  interferon alpha-4-like [KO:K05414]
710654  IFNA10; interferon alpha-4 precursor [KO:K05414]
711252  IFNA21; interferon alpha-21 [KO:K05414]
709559  IFNA13; interferon alpha-1/13 precursor [KO:K05414]
711088  interferon alpha-17-like [KO:K05414]
106992322  interferon alpha-17 [KO:K05414]
710848  interferon alpha-17 [KO:K05414]
106995851  IFNA6; interferon alpha-6 [KO:K05414]
114672663  interferon alpha-17-like [KO:K05414]
114672664  interferon alpha-17-like [KO:K05414]
718970  IRF3; interferon regulatory factor 3 [KO:K05411]
706258  EP300; histone acetyltransferase p300 [KO:K04498] [EC:2.3.1.48]
704331  CREBBP; CREB-binding protein [KO:K04498] [EC:2.3.1.48]
711414  IFNB1; interferon beta precursor [KO:K05415]
699604  IFNAR1; interferon alpha/beta receptor 1 precursor [KO:K05130]
699726  IFNAR2; interferon alpha/beta receptor 2 isoform X1 [KO:K05131]
677689  JAK1; tyrosine-protein kinase JAK1 [KO:K11217] [EC:2.7.10.2]
574130  TYK2; non-receptor tyrosine-protein kinase TYK2 isoform X1 [KO:K11219] [EC:2.7.10.2]
693650  STAT1; signal transducer and activator of transcription 1-alpha/beta [KO:K11220]
712694  STAT2; signal transducer and activator of transcription 2 [KO:K11221]
715335  IRF9; interferon regulatory factor 9 [KO:K04693]
708912  EIF2AK2; interferon-induced, double-stranded RNA-activated protein kinase [KO:K16195] [EC:2.7.11.1]
715745  MAPK12; mitogen-activated protein kinase 12 isoform X1 [KO:K04441] [EC:2.7.11.24]
715794  MAPK11; mitogen-activated protein kinase 11 [KO:K04441] [EC:2.7.11.24]
718976  MAPK14; mitogen-activated protein kinase 14 isoform X1 [KO:K04441] [EC:2.7.11.24]
719085  MAPK13; mitogen-activated protein kinase 13 isoform X1 [KO:K04441] [EC:2.7.11.24]
695044  MAPKAPK2; MAP kinase-activated protein kinase 2 isoform X2 [KO:K04443] [EC:2.7.11.1]
693914  MAP2K6; dual specificity mitogen-activated protein kinase kinase 6 [KO:K04433] [EC:2.7.12.2]
722000  ZFP36; mRNA decay activator protein ZFP36 [KO:K15308]
705819  IL6; interleukin-6 precursor [KO:K05405]
574371  CSF2; granulocyte-macrophage colony-stimulating factor precursor [KO:K05427]
713368  CCR3; C-C chemokine receptor type 3 [KO:K04178]
735311  CCR5; C-C chemokine receptor type 5 [KO:K04180]
574188  CCR1; C-C chemokine receptor type 1 [KO:K04176]
705457  CCR4; C-C chemokine receptor type 4 [KO:K04179]
693806  CCR8; C-C chemokine receptor type 8 [KO:K04183]
574332  FAS; tumor necrosis factor receptor superfamily member 6 precursor [KO:K04390]
708606  FADD; FAS-associated death domain protein [KO:K02373]
702781  CASP8; caspase-8 isoform X1 [KO:K04398] [EC:3.4.22.61]
100426724  BID; BH3-interacting domain death agonist isoform X2 [KO:K04726]
718948  BAX; apoptosis regulator BAX [KO:K02159]
706534  BAK1; bcl-2 homologous antagonist/killer [KO:K14021]
114675515  bcl-2 homologous antagonist/killer-like [KO:K14021]
705449  cytochrome c-like [KO:K08738]
716056  cytochrome c-like [KO:K08738]
711309  cytochrome c-like [KO:K08738]
698225  cytochrome c-like [KO:K08738]
701246  cytochrome c-like [KO:K08738]
699951  cytochrome c-like [KO:K08738]
702488  cytochrome c-like [KO:K08738]
100425223  CYCS; cytochrome c [KO:K08738]
106995399  cytochrome c-like [KO:K08738]
712148  cytochrome c-like [KO:K08738]
694544  CASP9; caspase-9 [KO:K04399] [EC:3.4.22.62]
694473  CASP3; caspase-3 [KO:K02187] [EC:3.4.22.56]
722033  TNFRSF1A; tumor necrosis factor receptor superfamily member 1A [KO:K03158]
698160  TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein isoform X1 [KO:K03171]
708391  TRAF2; TNF receptor-associated factor 2 [KO:K03173] [EC:2.3.2.27]
709511  CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X3 [KO:K04467] [EC:2.7.11.10]
704683  IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta [KO:K07209] [EC:2.7.11.10]
701237  IKBKG; NF-kappa-B essential modulator isoform X1 [KO:K07210]
695335  NFKBIA; NF-kappa-B inhibitor alpha [KO:K04734]
710324  NFKB1; nuclear factor NF-kappa-B p105 subunit [KO:K02580]
715919  RELA; transcription factor p65 isoform X1 [KO:K04735]
716170  TP53; cellular tumor antigen p53 [KO:K04451]
719199  CDKN1A; cyclin-dependent kinase inhibitor 1 [KO:K06625]
715650  CDK4; cyclin-dependent kinase 4 [KO:K02089] [EC:2.7.11.22]
701822  CDK6; cyclin-dependent kinase 6 [KO:K02091] [EC:2.7.11.22]
704871  RB1; retinoblastoma-associated protein [KO:K06618]
714126  E2F1; transcription factor E2F1 [KO:K17454]
710200  E2F2; transcription factor E2F2 [KO:K09389]
713904  E2F3; transcription factor E2F3 isoform X1 [KO:K06620]
694372  class I histocompatibility antigen, Gogo-B*0103 alpha chain-like isoform X1 [KO:K06751]
709076  MAMU-F; mamu class I histocompatibility antigen, alpha chain F precursor [KO:K06751]
711832  MAMU-A; major histocompatibility complex, class I, A isoform X1 [KO:K06751]
723473  patr class I histocompatibility antigen, B-1 alpha chain-like precursor [KO:K06751]
711532  MAMU-E; major histocompatibility complex, class I, E precursor [KO:K06751]
699243  MAMU-A3; major histocompatibility complex, class I, A isoform X1 [KO:K06751]
714964  LOW QUALITY PROTEIN: HLA class I histocompatibility antigen, B-67 alpha chain-like [KO:K06751]
719702  HLA class I histocompatibility antigen, B-46 alpha chain-like precursor [KO:K06751]
100187576  MAMU-AG; major histocompatibility complex, class I, AG precursor [KO:K06751]
719250  HLA class I histocompatibility antigen, B-14 alpha chain isoform X7 [KO:K06751]
106995452  saoe class I histocompatibility antigen, A alpha chain-like isoform X1 [KO:K06751]
100426197  class I histocompatibility antigen, Gogo-B*0101 alpha chain-like isoform X1 [KO:K06751]
100424348  HLA class I histocompatibility antigen, B-14 alpha chain isoform X1 [KO:K06751]
106996676  LOW QUALITY PROTEIN: HLA class I histocompatibility antigen, B-46 alpha chain-like [KO:K06751]
106996627  HLA class I histocompatibility antigen, B-15 alpha chain-like isoform X1 [KO:K06751]
114676051  LOW QUALITY PROTEIN: HLA class I histocompatibility antigen, B-14 alpha chain-like [KO:K06751]
106997893  HLA class I histocompatibility antigen, B-15 alpha chain-like isoform X1 [KO:K06751]
114677644  LOW QUALITY PROTEIN: class I histocompatibility antigen, Gogo-B*0103 alpha chain-like [KO:K06751]
720132  HLA class I histocompatibility antigen, B-38 alpha chain-like [KO:K06751]
100423877  IFNGR1; interferon gamma receptor 1 precursor [KO:K05132]
712280  ICAM1; intercellular adhesion molecule 1 precursor [KO:K06490]
714390  CD86; T-lymphocyte activation antigen CD86 precursor [KO:K05413]
715141  MICB; MHC class I polypeptide-related sequence B precursor [KO:K07985]
100141395  CD9; CD9 antigen [KO:K07985]
717347  CLEC2B; C-type lectin domain family 2 member B [KO:K10071]
720243  UBA52; ubiquitin-60S ribosomal protein L40 [KO:K02927]
708161  ubiquitin-like isoform X2 [KO:K02927]
704498  ubiquitin [KO:K02927]
718909  RPS27A; 40S ribosomal protein S27a [KO:K02977]
106992282  RPS27A; ubiquitin-40S ribosomal protein S27a [KO:K02977]
696110  UBB; polyubiquitin-B [KO:K04551]
712934  UBC; LOW QUALITY PROTEIN: polyubiquitin-C [KO:K08770]
711649  BECN1; Beclin-1 [KO:K08334]
715431  BECN2; beclin-2 [KO:K08334]
697252  ATG14; beclin 1-associated autophagy-related key regulator [KO:K17889]
693918  PIK3C3; phosphatidylinositol 3-kinase catalytic subunit type 3 [KO:K00914] [EC:2.7.1.137]
708305  ATG3; ubiquitin-like-conjugating enzyme ATG3 [KO:K08343]
706487  MAP1LC3C; microtubule-associated proteins 1A/1B light chain 3C [KO:K10435]
695419  MAP1LC3B; microtubule-associated proteins 1A/1B light chain 3B [KO:K10435]
707439  MAP1LC3A; microtubule-associated proteins 1A/1B light chain 3A [KO:K10435]
697790  microtubule-associated proteins 1A/1B light chain 3B [KO:K10435]
703399  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 [KO:K04536]
719248  GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 [KO:K04537]
713913  GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 [KO:K07825]
709489  GNB4; guanine nucleotide-binding protein subunit beta-4 [KO:K04538]
695441  GNB5; guanine nucleotide-binding protein subunit beta-5 isoform X1 [KO:K04539]
710000  GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 [KO:K07826]
100169972  GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 [KO:K04540]
718223  GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 [KO:K04541]
703336  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 [KO:K04542]
710548  GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 [KO:K04542]
711335  GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 [KO:K04543]
114673987  GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 isoform X1 [KO:K04544]
708193  GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 [KO:K04545]
700606  GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 [KO:K04546]
100424606  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 [KO:K04347]
114673968  GNG14; putative guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-14 [KO:K04347]
722398  GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 [KO:K04547]
700724  GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1 [KO:K04548]
698840  GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 [KO:K04549]
698830  HRAS; GTPase HRas [KO:K02833]
707977  KRAS; GTPase KRas [KO:K07827]
709089  NRAS; GTPase NRas [KO:K07828]
694725  RAF1; RAF proto-oncogene serine/threonine-protein kinase [KO:K04366] [EC:2.7.11.1]
710415  MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 [KO:K04368] [EC:2.7.12.2]
721821  MAP2K2; dual specificity mitogen-activated protein kinase kinase 2 isoform X1 [KO:K04369] [EC:2.7.12.2]
708938  MAPK3; mitogen-activated protein kinase 3 isoform X1 [KO:K04371] [EC:2.7.11.24]
698569  MAPK1; mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
704678  HIF1A; hypoxia-inducible factor 1-alpha isoform X4 [KO:K08268]
716452  JUN; transcription factor AP-1 [KO:K04448]
702077  FOS; proto-oncogene c-Fos [KO:K04379]
698857  PIK3CG; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform [KO:K21289] [EC:2.7.1.153]
722027  PIK3R5; phosphoinositide 3-kinase regulatory subunit 5 isoform X1 [KO:K21290]
722023  PIK3R6; phosphoinositide 3-kinase regulatory subunit 6 [KO:K21290]
716098  PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
709959  PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
710552  PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
707310  PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma [KO:K02649]
719367  PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta [KO:K02649]
698996  PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha [KO:K02649]
714717  AKT3; RAC-gamma serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
697747  AKT1; RAC-alpha serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
700591  AKT2; RAC-beta serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
106992736  MTOR; serine/threonine-protein kinase mTOR [KO:K07203] [EC:2.7.11.1]
714351  PREX1; phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein [KO:K12365]
717755  RAC1; ras-related C3 botulinum toxin substrate 1 isoform X1 [KO:K04392]
699736  MAPK10; mitogen-activated protein kinase 10 isoform 1 [KO:K04440] [EC:2.7.11.24]
711115  MAPK8; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
715782  MAPK9; mitogen-activated protein kinase 9 isoform X2 [KO:K04440] [EC:2.7.11.24]
708622  cell surface glycoprotein CD200 receptor 2-like isoform X1 [KO:K21668]
708734  CD200R1; cell surface glycoprotein CD200 receptor 1 precursor [KO:K21668]
704102  SYK; tyrosine-protein kinase SYK [KO:K05855] [EC:2.7.10.2]
701057  SRC; proto-oncogene tyrosine-protein kinase Src [KO:K05704] [EC:2.7.10.2]
715723  HCK; tyrosine-protein kinase HCK [KO:K08893] [EC:2.7.10.2]
698553  LYN; tyrosine-protein kinase Lyn isoform X1 [KO:K05854] [EC:2.7.10.2]
718155  MAP2K4; dual specificity mitogen-activated protein kinase kinase 4 isoform X1 [KO:K04430] [EC:2.7.12.2]
710077  MAP2K7; dual specificity mitogen-activated protein kinase kinase 7 isoform X1 [KO:K04431] [EC:2.7.12.2]
714173  PLCG2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform X1 [KO:K05859] [EC:3.1.4.11]
697069  PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1 [KO:K01116] [EC:3.1.4.11]
703669  ITPR1; inositol 1,4,5-trisphosphate receptor type 1 isoform X1 [KO:K04958]
708714  ITPR2; inositol 1,4,5-trisphosphate receptor type 2 isoform X1 [KO:K04959]
718040  ITPR3; inositol 1,4,5-trisphosphate receptor type 3 isoform X1 [KO:K04960]
717686  calmodulin [KO:K02183]
698552  CALM1; calmodulin-1 isoform X1 [KO:K02183]
715270  CALM2; calmodulin-2 [KO:K02183]
703514  CALML6; calmodulin-like protein 6 isoform X1 [KO:K02183]
712159  CALML5; calmodulin-like protein 5 [KO:K02183]
722513  CALML3; calmodulin-like protein 3 [KO:K02183]
716584  CALM3; calmodulin-3 isoform X1 [KO:K02183]
693753  CALML4; LOW QUALITY PROTEIN: calmodulin-like protein 4 [KO:K02183]
706351  calmodulin-like [KO:K02183]
706955  PPP3CB; serine/threonine-protein phosphatase 2B catalytic subunit beta isoform isoform X7 [KO:K04348] [EC:3.1.3.16]
708233  PPP3CC; serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform isoform X2 [KO:K04348] [EC:3.1.3.16]
709773  PPP3CA; serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform [KO:K04348] [EC:3.1.3.16]
574258  PPP3R2; calcineurin subunit B type 2 [KO:K06268]
100428682  PPP3R1; calcineurin subunit B type 1 isoform X3 [KO:K06268]
698089  NFATC1; nuclear factor of activated T-cells, cytoplasmic 1 isoform X2 [KO:K04446]
710601  NFATC2; nuclear factor of activated T-cells, cytoplasmic 2 isoform X1 [KO:K17332]
702390  NFATC3; nuclear factor of activated T-cells, cytoplasmic 3 isoform X2 [KO:K17333]
714785  NFATC4; nuclear factor of activated T-cells, cytoplasmic 4 isoform X2 [KO:K17334]
613028  CXCL8; interleukin-8 precursor [KO:K10030]
716671  PTGS2; prostaglandin G/H synthase 2 [KO:K11987] [EC:1.14.99.1]
574222  CXCL1; growth-regulated alpha protein precursor [KO:K05505]
703390  growth-regulated alpha protein-like [KO:K05505]
702067  uncharacterized protein LOC702067 [KO:K05505]
100424064  growth-regulated alpha protein-like [KO:K05505]
574223  CXCL3; C-X-C motif chemokine 3 precursor [KO:K05505]
697108  RCAN1; calcipressin-1 isoform X2 [KO:K17901]
574136  FGF2; fibroblast growth factor 2 [KO:K18497]
574209  VEGFA; vascular endothelial growth factor A isoform 1 precursor [KO:K05448]
703173  PDGFB; platelet-derived growth factor subunit B [KO:K17386]
716811  ANGPT2; angiopoietin-2 isoform X1 [KO:K05466]
574127  IL6ST; interleukin-6 receptor subunit beta precursor [KO:K05060]
694184  JAK2; tyrosine-protein kinase JAK2 [KO:K04447] [EC:2.7.10.2]
574128  STAT3; signal transducer and activator of transcription 3 isoform X1 [KO:K04692]
713114  GSK3B; glycogen synthase kinase-3 beta isoform X1 [KO:K03083] [EC:2.7.11.26]
574265  CTNNB1; catenin beta-1 [KO:K02105]
710234  TCF7; transcription factor 7 isoform X3 [KO:K02620]
694560  TCF7L1; transcription factor 7-like 1 isoform X2 [KO:K04490]
701759  TCF7L2; transcription factor 7-like 2 isoform X9 [KO:K04491]
695776  LEF1; lymphoid enhancer-binding factor 1 isoform X3 [KO:K04492]
708717  CREB1; cyclic AMP-responsive element-binding protein 1 [KO:K05870]
574320  CCND1; G1/S-specific cyclin-D1 [KO:K04503]
694626  MYC; myc proto-oncogene protein [KO:K04377]
Compound
C00076  Calcium cation
C00165  Diacylglycerol
C00350  Phosphatidylethanolamine
C01245  D-myo-Inositol 1,4,5-trisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
Reference
PMID:22403573
  Authors
Lee HR, Brulois K, Wong L, Jung JU
  Title
Modulation of Immune System by Kaposi's Sarcoma-Associated Herpesvirus: Lessons from Viral Evasion Strategies.
  Journal
Front Microbiol 3:44 (2012)
DOI:10.3389/fmicb.2012.00044
Reference
PMID:18948197
  Authors
Liang C, Lee JS, Jung JU
  Title
Immune evasion in Kaposi's sarcoma-associated herpes virus associated oncogenesis.
  Journal
Semin Cancer Biol 18:423-36 (2008)
DOI:10.1016/j.semcancer.2008.09.003
Reference
PMID:21040832
  Authors
Cai Q, Verma SC, Lu J, Robertson ES
  Title
Molecular biology of Kaposi's sarcoma-associated herpesvirus and related oncogenesis.
  Journal
Adv Virus Res 78:87-142 (2010)
DOI:10.1016/B978-0-12-385032-4.00003-3
Reference
PMID:16760382
  Authors
Rezaee SA, Cunningham C, Davison AJ, Blackbourn DJ
  Title
Kaposi's sarcoma-associated herpesvirus immune modulation: an overview.
  Journal
J Gen Virol 87:1781-804 (2006)
DOI:10.1099/vir.0.81919-0
Reference
PMID:19230674
  Authors
Areste C, Blackbourn DJ
  Title
Modulation of the immune system by Kaposi's sarcoma-associated herpesvirus.
  Journal
Trends Microbiol 17:119-29 (2009)
DOI:10.1016/j.tim.2008.12.001
Reference
PMID:16905191
  Authors
Mark L, Spiller OB, Villoutreix BO, Blom AM
  Title
Kaposi's sarcoma-associated herpes virus complement control protein: KCP--complement inhibition and more.
  Journal
Mol Immunol 44:11-22 (2007)
DOI:10.1016/j.molimm.2006.06.018
Reference
PMID:11500830
  Authors
Weber KS, Grone HJ, Rocken M, Klier C, Gu S, Wank R, Proudfoot AE, Nelson PJ, Weber C
  Title
Selective recruitment of Th2-type cells and evasion from a cytotoxic immune response mediated by viral macrophage inhibitory protein-II.
  Journal
Eur J Immunol 31:2458-66 (2001)
DOI:10.1002/1521-4141(200108)31:8<2458::AID-IMMU2458>3.0.CO;2-L
Reference
PMID:10666184
  Authors
Stine JT, Wood C, Hill M, Epp A, Raport CJ, Schweickart VL, Endo Y, Sasaki T, Simmons G, Boshoff C, Clapham P, Chang Y, Moore P, Gray PW, Chantry D
  Title
KSHV-encoded CC chemokine vMIP-III is a CCR4 agonist, stimulates angiogenesis, and selectively chemoattracts TH2 cells.
  Journal
Blood 95:1151-7 (2000)
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KO pathway
ko05167   
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