KEGG   PATHWAY: btax05170
Entry
btax05170                   Pathway                                
Name
Human immunodeficiency virus 1 infection - Budorcas taxicolor (takin)
Description
Human immunodeficiency virus type 1 (HIV-1) , the causative agent of AIDS (acquired immunodeficiency syndrome), is a lentivirus belonging to the Retroviridae family. The primary cell surface receptor for HIV-1, the CD4 protein, and the co-receptor for HIV-1, either CCR5 or CXCR4, are found on macrophages and T lymphocytes. At the earliest step, sequential binding of virus envelope (Env) glycoprotein gp120 to CD4 and the co-receptor CCR5 or CXCR4 facilitates HIV-1 entry and has the potential to trigger critical signaling that may favor viral replication. At advanced stages of the disease, HIV-1 infection results in dramatic induction of T-cell (CD4+ T and CD8+ T cell) apoptosis both in infected and uninfected bystander T cells, a hallmark of HIV-1 pathogenesis. On the contrary, macrophages are resistant to the cytopathic effect of HIV-1 and produce virus for longer periods of time.
Class
Human Diseases; Infectious disease: viral
Pathway map
btax05170  Human immunodeficiency virus 1 infection
btax05170

Organism
Budorcas taxicolor (takin) [GN:btax]
Gene
128048680  CD4; T-cell surface glycoprotein CD4 [KO:K06454]
128065993  FBXW11; F-box/WD repeat-containing protein 11 isoform X1 [KO:K03362]
128067734  BTRC; F-box/WD repeat-containing protein 1A isoform X1 [KO:K03362]
128050765  SKP1; S-phase kinase-associated protein 1 [KO:K03094]
128058336  S-phase kinase-associated protein 1-like [KO:K03094]
128046705  S-phase kinase-associated protein 1-like [KO:K03094]
128066272  S-phase kinase-associated protein 1-like [KO:K03094]
128046241  CUL1; cullin-1 [KO:K03347]
128046932  cullin-1-like [KO:K03347]
128047495  RBX1; E3 ubiquitin-protein ligase RBX1 isoform X1 [KO:K03868] [EC:2.3.2.32]
128067535  E3 ubiquitin-protein ligase RBX1 [KO:K03868] [EC:2.3.2.32]
128070914  CXCR4; C-X-C chemokine receptor type 4 [KO:K04189]
128049778  C-C chemokine receptor type 5 [KO:K04180]
128044413  GNAI3; guanine nucleotide-binding protein G(i) subunit alpha-3 [KO:K04630]
128057155  GNAI2; guanine nucleotide-binding protein G(i) subunit alpha-2 [KO:K04630]
128046449  GNAI1; guanine nucleotide-binding protein G(i) subunit alpha-1 [KO:K04630]
128062941  GNAO1; guanine nucleotide-binding protein G(o) subunit alpha [KO:K04534]
128045803  PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
128061813  PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
128068699  PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
128050540  PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta [KO:K02649]
128044474  PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma [KO:K02649]
128066235  PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha [KO:K02649]
128059235  PTK2; focal adhesion kinase 1 isoform X1 [KO:K05725] [EC:2.7.10.2]
128052409  PTK2B; protein-tyrosine kinase 2-beta isoform X1 [KO:K05871] [EC:2.7.10.2]
128062630  PXN; paxillin isoform X1 [KO:K05760]
128064843  CRK; adapter molecule crk isoform X1 [KO:K04438]
128062501  CRKL; crk-like protein [KO:K04438]
128063870  AKT2; RAC-beta serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
128067048  AKT1; RAC-alpha serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
128061491  AKT3; RAC-gamma serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
128061687  MTOR; serine/threonine-protein kinase mTOR [KO:K07203] [EC:2.7.11.1]
128064578  RPS6KB1; ribosomal protein S6 kinase beta-1 [KO:K04688] [EC:2.7.11.1]
128068526  RPS6KB2; ribosomal protein S6 kinase beta-2 isoform X1 [KO:K04688] [EC:2.7.11.1]
128049417  NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1 [KO:K02580]
128068546  RELA; transcription factor p65 [KO:K04735]
128053951  FOS; protein c-Fos [KO:K04379]
128044447  JUN; transcription factor Jun [KO:K04448]
128068977  BAD; bcl2-associated agonist of cell death [KO:K02158]
128068689  HRAS; GTPase HRas isoform X1 [KO:K02833]
128047937  KRAS; GTPase KRas [KO:K07827]
128044537  NRAS; GTPase NRas [KO:K07828]
128043403  RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1 [KO:K04366] [EC:2.7.11.1]
128054045  MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 [KO:K04368] [EC:2.7.12.2]
128050664  MAP2K2; dual specificity mitogen-activated protein kinase kinase 2 [KO:K04369] [EC:2.7.12.2]
128043958  MAPK3; mitogen-activated protein kinase 3 [KO:K04371] [EC:2.7.11.24]
128062160  MAPK1; mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
128052307  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha [KO:K04634]
128050674  GNA11; guanine nucleotide-binding protein subunit alpha-11 [KO:K04635]
128058189  PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1 [KO:K01116] [EC:3.1.4.11]
128063111  PLCG2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 [KO:K05859] [EC:3.1.4.11]
128046429  ITPR1; inositol 1,4,5-trisphosphate receptor type 1 [KO:K04958]
128048527  ITPR2; inositol 1,4,5-trisphosphate receptor type 2 [KO:K04959]
128056281  ITPR3; inositol 1,4,5-trisphosphate receptor type 3 [KO:K04960]
128056684  CALM2; calmodulin-2 [KO:K02183]
128063810  CALM3; calmodulin-3 [KO:K02183]
128058230  calmodulin-like [KO:K02183]
128053757  CALML4; calmodulin-like protein 4 isoform X1 [KO:K02183]
128054267  CALM1; calmodulin-1 [KO:K02183]
128061269  CALML6; LOW QUALITY PROTEIN: calmodulin-like protein 6 [KO:K02183]
128052144  PPP3CC; serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform isoform X1 [KO:K04348] [EC:3.1.3.16]
128047312  PPP3CB; serine/threonine-protein phosphatase 2B catalytic subunit beta isoform [KO:K04348] [EC:3.1.3.16]
128049447  PPP3CA; protein phosphatase 3 catalytic subunit alpha isoform X1 [KO:K04348] [EC:3.1.3.16]
128052606  PPP3R2; calcineurin subunit B type 2 [KO:K06268]
128055318  PPP3R1; calcineurin subunit B type 1 [KO:K06268]
128067290  NFATC1; nuclear factor of activated T-cells, cytoplasmic 1 isoform X1 [KO:K04446]
128058335  NFATC2; nuclear factor of activated T-cells, cytoplasmic 2 isoform X1 [KO:K17332]
128064208  NFATC3; nuclear factor of activated T-cells, cytoplasmic 3 isoform X1 [KO:K17333]
128054080  NFATC4; nuclear factor of activated T-cells, cytoplasmic 4 [KO:K17334]
128065393  PRKCA; protein kinase C alpha type isoform X1 [KO:K02677] [EC:2.7.11.13]
128066420  PRKCB; protein kinase C beta type [KO:K19662] [EC:2.7.11.13]
128063096  PRKCG; protein kinase C gamma type [KO:K19663] [EC:2.7.11.13]
128061341  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 [KO:K04536]
128068195  GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 [KO:K04537]
128047979  GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 [KO:K07825]
128050433  GNB4; guanine nucleotide-binding protein subunit beta-4 [KO:K04538]
128054091  GNB5; guanine nucleotide-binding protein subunit beta-5 [KO:K04539]
128068668  GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 [KO:K04540]
128048580  GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 [KO:K04541]
128046927  guanine nucleotide-binding protein G(T) subunit gamma-T1 [KO:K04548]
128043471  RAC1; ras-related C3 botulinum toxin substrate 1 [KO:K04392]
128047644  RAC2; ras-related C3 botulinum toxin substrate 2 [KO:K07860]
128065663  RAC3; ras-related C3 botulinum toxin substrate 3 [KO:K07861]
128068496  PAK1; serine/threonine-protein kinase PAK 1 [KO:K04409] [EC:2.7.11.1]
128057235  PAK2; serine/threonine-protein kinase PAK 2 [KO:K04410] [EC:2.7.11.1]
128069841  PAK3; serine/threonine-protein kinase PAK 3 [KO:K05733] [EC:2.7.11.1]
128062878  PAK4; serine/threonine-protein kinase PAK 4 [KO:K05734] [EC:2.7.11.1]
128058601  PAK5; serine/threonine-protein kinase PAK 5 [KO:K05736] [EC:2.7.11.1]
128054088  PAK6; serine/threonine-protein kinase PAK 6 [KO:K05735] [EC:2.7.11.1]
128066654  LIMK1; LIM domain kinase 1 [KO:K05743] [EC:2.7.11.1]
128062055  LIMK2; LIM domain kinase 2 isoform X1 [KO:K05744] [EC:2.7.11.1]
128066553  CFL2; cofilin-2 [KO:K05765]
128068771  CFL1; cofilin-1 [KO:K05765]
128056772  TNF; tumor necrosis factor [KO:K03156]
128061416  TNFRSF1B; tumor necrosis factor receptor superfamily member 1B [KO:K05141]
128058470  BCL2L1; bcl-2-like protein 1 [KO:K04570]
128059210  LOW QUALITY PROTEIN: bcl-2-like protein 1 [KO:K04570]
128062410  TLR2; toll-like receptor 2 [KO:K10159]
128052396  TLR4; toll-like receptor 4 [KO:K10160]
128049046  MYD88; myeloid differentiation primary response protein MyD88 [KO:K04729]
128048533  IRAK4; interleukin-1 receptor-associated kinase 4 [KO:K04733] [EC:2.7.11.1]
128069805  IRAK1; interleukin-1 receptor-associated kinase 1 [KO:K04730] [EC:2.7.11.1]
128060227  TRAF6; TNF receptor-associated factor 6 [KO:K03175] [EC:2.3.2.27]
128049014  TAB1; TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 [KO:K04403]
128053126  TAB2; TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 [KO:K04404]
128053252  MAP3K7; mitogen-activated protein kinase kinase kinase 7 [KO:K04427] [EC:2.7.11.25]
128067677  CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1 [KO:K04467] [EC:2.7.11.10]
128068238  IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1 [KO:K07209] [EC:2.7.11.10]
128069947  IKBKG; NF-kappa-B essential modulator isoform X1 [KO:K07210]
128066643  NFKBIA; NF-kappa-B inhibitor alpha [KO:K04734]
128052429  interferon alpha-H-like [KO:K05414]
128052430  interferon alpha-H-like [KO:K05414]
128052431  interferon alpha-H [KO:K05414]
128052432  interferon alpha-1-like [KO:K05414]
128052433  interferon alpha-H-like [KO:K05414]
128052459  interferon alpha-H-like [KO:K05414]
128052476  interferon alpha-H-like [KO:K05414]
128052682  LOW QUALITY PROTEIN: interferon alpha-3-like [KO:K05414]
128052694  interferon alpha-H-like [KO:K05414]
128052696  interferon alpha-H-like [KO:K05414]
128052697  interferon alpha-1-like [KO:K05414]
128052706  LOW QUALITY PROTEIN: interferon alpha-2-like [KO:K05414]
128052625  interferon beta-2-like [KO:K05415]
128052626  interferon beta-2-like [KO:K05415]
128052627  interferon beta-2-like [KO:K05415]
128052628  interferon beta-2 [KO:K05415]
128052635  interferon beta-2-like [KO:K05415]
128052636  interferon beta-2-like [KO:K05415]
128052637  interferon beta-2-like [KO:K05415]
128052638  interferon beta-2-like [KO:K05415]
128052639  interferon beta-2-like [KO:K05415]
128052640  interferon beta-2-like [KO:K05415]
128052652  interferon beta-2-like [KO:K05415]
128047426  MAPK11; mitogen-activated protein kinase 11 [KO:K04441] [EC:2.7.11.24]
128048391  MAPK12; mitogen-activated protein kinase 12 [KO:K04441] [EC:2.7.11.24]
128055294  MAPK14; mitogen-activated protein kinase 14 [KO:K04441] [EC:2.7.11.24]
128055801  MAPK13; mitogen-activated protein kinase 13 [KO:K04441] [EC:2.7.11.24]
128051495  MAPK9; mitogen-activated protein kinase 9 isoform X1 [KO:K04440] [EC:2.7.11.24]
128047244  MAPK8; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
128049619  MAPK10; mitogen-activated protein kinase 10 [KO:K04440] [EC:2.7.11.24]
128053541  CGAS; cyclic GMP-AMP synthase [KO:K17834] [EC:2.7.7.86]
128050274  STING1; stimulator of interferon genes protein [KO:K12654]
128047841  TBK1; serine/threonine-protein kinase TBK1 [KO:K05410] [EC:2.7.11.10]
128062922  IRF3; interferon regulatory factor 3 isoform X1 [KO:K05411]
128047831  DNA dC->dU-editing enzyme APOBEC-3C-like isoform X1 [KO:K18750] [EC:3.5.4.-]
128058346  SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 isoform X1 [KO:K22544] [EC:3.1.5.-]
128060077  tripartite motif-containing protein 5-like [KO:K10648] [EC:2.3.2.27]
128060113  LOW QUALITY PROTEIN: tripartite motif-containing protein 5-like [KO:K10648] [EC:2.3.2.27]
128060084  LOW QUALITY PROTEIN: tripartite motif-containing protein 5-like [KO:K10648] [EC:2.3.2.27]
128050402  uncharacterized protein LOC128050402 [KO:K06731]
128050403  uncharacterized protein LOC128050403 [KO:K06731]
128051673  bone marrow stromal antigen 2-like [KO:K06731]
128047668  TNFRSF1A; tumor necrosis factor receptor superfamily member 1A isoform X1 [KO:K03158]
128055992  RIPK1; receptor-interacting serine/threonine-protein kinase 1 isoform X1 [KO:K02861] [EC:2.7.11.1]
128063092  TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein [KO:K03171]
128061711  TRAF5; TNF receptor-associated factor 5 [KO:K09849]
128055475  TRAF2; TNF receptor-associated factor 2 [KO:K03173] [EC:2.3.2.27]
128064641  MAP2K3; dual specificity mitogen-activated protein kinase kinase 3 isoform X1 [KO:K04432] [EC:2.7.12.2]
128065178  MAP2K6; dual specificity mitogen-activated protein kinase kinase 6 isoform X1 [KO:K04433] [EC:2.7.12.2]
128050697  MAP2K7; dual specificity mitogen-activated protein kinase kinase 7 isoform X1 [KO:K04431] [EC:2.7.12.2]
128061812  FASLG; tumor necrosis factor ligand superfamily member 6 [KO:K04389]
128067871  FAS; tumor necrosis factor receptor superfamily member 6 [KO:K04390]
128068641  FADD; FAS-associated death domain protein [KO:K02373]
128064775  CASP8; caspase-8 [KO:K04398] [EC:3.4.22.61]
128047923  BID; BH3-interacting domain death agonist [KO:K04726]
128064207  BAX; apoptosis regulator BAX [KO:K02159]
128056082  BAK1; bcl-2 homologous antagonist/killer isoform X1 [KO:K14021]
128067358  BCL2; apoptosis regulator Bcl-2 isoform X1 [KO:K02161]
128069489  cytochrome c 2 [KO:K08738]
128046227  cytochrome c [KO:K08738]
128053843  cytochrome c-like [KO:K08738]
128053924  cytochrome c [KO:K08738]
128054019  cytochrome c-like [KO:K08738]
128061241  CASP9; caspase-9 [KO:K04399] [EC:3.4.22.62]
128068336  CASP3; caspase-3 [KO:K02187] [EC:3.4.22.56]
128060834  T-cell surface glycoprotein CD3 epsilon chain [KO:K06451]
128060507  T-cell surface glycoprotein CD3 gamma chain [KO:K06452]
128060506  T-cell surface glycoprotein CD3 delta chain [KO:K06450]
128045120  CD247; T-cell surface glycoprotein CD3 zeta chain [KO:K06453]
128056161  TAP1; antigen peptide transporter 1 [KO:K05653] [EC:7.4.2.14]
128056049  TAP2; antigen peptide transporter 2 [KO:K05654] [EC:7.4.2.14]
128055536  TAPBP; tapasin [KO:K08058]
128066552  PDIA3; protein disulfide-isomerase A3 [KO:K08056] [EC:5.3.4.1]
128050932  CALR; calreticulin [KO:K08057]
128050979  H-2 class I histocompatibility antigen, Q10 alpha chain-like [KO:K06751]
128055236  LOW QUALITY PROTEIN: BOLA class I histocompatibility antigen, alpha chain BL3-7-like [KO:K06751]
128055280  LOW QUALITY PROTEIN: BOLA class I histocompatibility antigen, alpha chain BL3-7-like [KO:K06751]
128055281  LOW QUALITY PROTEIN: BOLA class I histocompatibility antigen, alpha chain BL3-7-like [KO:K06751]
128055305  BOLA class I histocompatibility antigen, alpha chain BL3-7-like [KO:K06751]
128062062  AP1B1; AP-1 complex subunit beta-1 isoform X1 [KO:K12392]
128053872  AP1G2; AP-1 complex subunit gamma-like 2 [KO:K12391]
128062961  AP1G1; AP-1 complex subunit gamma-1 [KO:K12391]
128050668  AP1M1; AP-1 complex subunit mu-1 [KO:K12393]
128051364  AP1M2; AP-1 complex subunit mu-2 [KO:K12393]
128043295  AP1S1; AP-1 complex subunit sigma-1A [KO:K12394]
128069986  AP1S2; AP-1 complex subunit sigma-2 [KO:K12394]
128043446  AP1S3; AP-1 complex subunit sigma-3 [KO:K12395]
128053799  beta-2-microglobulin [KO:K08055]
128053800  beta-2-microglobulin [KO:K08055]
128054804  elongin-B-like [KO:K03873]
128067690  ELOB; elongin-B [KO:K03873]
128059104  ELOC; elongin-C [KO:K03872]
128060400  CUL5; LOW QUALITY PROTEIN: cullin-5 [KO:K10612]
128048644  RNF7; RING-box protein 2 [KO:K10611]
128051204  DCAF1; DDB1- and CUL4-associated factor 1 isoform X1 [KO:K11789] [EC:2.7.11.1]
128069247  DDB1; DNA damage-binding protein 1 [KO:K10610]
128069855  CUL4B; cullin-4B [KO:K10609]
128057766  CUL4A; cullin-4A isoform X1 [KO:K10609]
128060504  ATM; serine-protein kinase ATM [KO:K04728] [EC:2.7.11.1]
128053092  ATR; serine/threonine-protein kinase ATR [KO:K06640] [EC:2.7.11.1]
128068939  CHEK1; LOW QUALITY PROTEIN: serine/threonine-protein kinase Chk1 [KO:K02216] [EC:2.7.11.1]
128051380  CDC25C; M-phase inducer phosphatase 3 [KO:K05867] [EC:3.1.3.48]
128046943  WEE2; wee1-like protein kinase 2 [KO:K06632] [EC:2.7.11.1]
128060398  WEE1; wee1-like protein kinase [KO:K06632] [EC:2.7.11.1]
128066149  CCNB1; G2/mitotic-specific cyclin-B1 [KO:K05868]
128066902  G2/mitotic-specific cyclin-B1-like [KO:K05868]
128054390  CCNB2; G2/mitotic-specific cyclin-B2 [KO:K21770]
128070382  CCNB3; G2/mitotic-specific cyclin-B3 [KO:K21771]
128048047  CDK1; cyclin-dependent kinase 1 [KO:K02087] [EC:2.7.11.22 2.7.11.23]
Compound
C00076  Calcium cation
C00165  Diacylglycerol
C01245  D-myo-Inositol 1,4,5-trisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C20640  Cyclic GMP-AMP
Reference
PMID:22749173
  Authors
Evans VA, Khoury G, Saleh S, Cameron PU, Lewin SR
  Title
HIV persistence: chemokines and their signalling pathways.
  Journal
Cytokine Growth Factor Rev 23:151-7 (2012)
DOI:10.1016/j.cytogfr.2012.05.002
Reference
PMID:23806647
  Authors
Abbas W, Herbein G
  Title
Plasma membrane signaling in HIV-1 infection.
  Journal
Biochim Biophys Acta 1838:1132-42 (2014)
DOI:10.1016/j.bbamem.2013.06.020
Reference
PMID:20041213
  Authors
Wu Y, Yoder A
  Title
Chemokine coreceptor signaling in HIV-1 infection and pathogenesis.
  Journal
PLoS Pathog 5:e1000520 (2009)
DOI:10.1371/journal.ppat.1000520
Reference
PMID:22085380
  Authors
Choi WT, Duggineni S, Xu Y, Huang Z, An J
  Title
Drug discovery research targeting the CXC chemokine receptor 4 (CXCR4).
  Journal
J Med Chem 55:977-94 (2012)
DOI:10.1021/jm200568c
Reference
PMID:21321123
  Authors
Vorster PJ, Guo J, Yoder A, Wang W, Zheng Y, Xu X, Yu D, Spear M, Wu Y
  Title
LIM kinase 1 modulates cortical actin and CXCR4 cycling and is activated by HIV-1 to initiate viral infection.
  Journal
J Biol Chem 286:12554-64 (2011)
DOI:10.1074/jbc.M110.182238
Reference
PMID:15817946
  Authors
Das SR, Jameel S
  Title
Biology of the HIV Nef protein.
  Journal
Indian J Med Res 121:315-32 (2005)
Reference
PMID:24822052
  Authors
Roy N, Pacini G, Berlioz-Torrent C, Janvier K
  Title
Mechanisms underlying HIV-1 Vpu-mediated viral egress.
  Journal
Front Microbiol 5:177 (2014)
DOI:10.3389/fmicb.2014.00177
Reference
PMID:22090097
  Authors
Magadan JG, Bonifacino JS
  Title
Transmembrane domain determinants of CD4 Downregulation by HIV-1 Vpu.
  Journal
J Virol 86:757-72 (2012)
DOI:10.1128/JVI.05933-11
Reference
PMID:26056579
  Authors
Kumar A, Herbein G
  Title
The macrophage: a therapeutic target in HIV-1 infection.
  Journal
Mol Cell Ther 2:10 (2014)
DOI:10.1186/2052-8426-2-10
Reference
PMID:20672047
  Authors
Yokota S, Okabayashi T, Fujii N
  Title
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Related
pathway
btax03050  Proteasome
btax04010  MAPK signaling pathway
btax04020  Calcium signaling pathway
btax04064  NF-kappa B signaling pathway
btax04110  Cell cycle
btax04141  Protein processing in endoplasmic reticulum
btax04142  Lysosome
btax04150  mTOR signaling pathway
btax04151  PI3K-Akt signaling pathway
btax04210  Apoptosis
btax04612  Antigen processing and presentation
btax04620  Toll-like receptor signaling pathway
btax04623  Cytosolic DNA-sensing pathway
btax04668  TNF signaling pathway
btax04810  Regulation of actin cytoskeleton
KO pathway
ko05170   
LinkDB

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