KEGG   PATHWAY: npo05170
Entry
npo05170                    Pathway                                
Name
Human immunodeficiency virus 1 infection - Nyctereutes procyonoides (raccoon dog)
Description
Human immunodeficiency virus type 1 (HIV-1) , the causative agent of AIDS (acquired immunodeficiency syndrome), is a lentivirus belonging to the Retroviridae family. The primary cell surface receptor for HIV-1, the CD4 protein, and the co-receptor for HIV-1, either CCR5 or CXCR4, are found on macrophages and T lymphocytes. At the earliest step, sequential binding of virus envelope (Env) glycoprotein gp120 to CD4 and the co-receptor CCR5 or CXCR4 facilitates HIV-1 entry and has the potential to trigger critical signaling that may favor viral replication. At advanced stages of the disease, HIV-1 infection results in dramatic induction of T-cell (CD4+ T and CD8+ T cell) apoptosis both in infected and uninfected bystander T cells, a hallmark of HIV-1 pathogenesis. On the contrary, macrophages are resistant to the cytopathic effect of HIV-1 and produce virus for longer periods of time.
Class
Human Diseases; Infectious disease: viral
Pathway map
npo05170  Human immunodeficiency virus 1 infection
npo05170

Organism
Nyctereutes procyonoides (raccoon dog) [GN:npo]
Gene
129503501  CD4; T-cell surface glycoprotein CD4 [KO:K06454]
129493733  BTRC; F-box/WD repeat-containing protein 1A isoform X1 [KO:K03362]
129509575  FBXW11; F-box/WD repeat-containing protein 11 isoform X1 [KO:K03362]
129501328  S-phase kinase-associated protein 1-like [KO:K03094]
129494987  SKP1; S-phase kinase-associated protein 1 [KO:K03094]
129515703  CUL1; cullin-1 [KO:K03347]
129511746  RBX1; E3 ubiquitin-protein ligase RBX1 isoform X1 [KO:K03868] [EC:2.3.2.32]
129495495  C-X-C chemokine receptor type 4 [KO:K04189]
129513052  C-X-C chemokine receptor type 4-like [KO:K04189]
129514745  C-X-C chemokine receptor type 4-like [KO:K04189]
129521913  CCR5; C-C chemokine receptor type 5 isoform X1 [KO:K04180]
129494269  GNAI1; guanine nucleotide-binding protein G(i) subunit alpha-1 [KO:K04630]
129519569  GNAI3; guanine nucleotide-binding protein G(i) subunit alpha-3 [KO:K04630]
129522106  GNAI2; guanine nucleotide-binding protein G(i) subunit alpha-2 [KO:K04630]
129513852  GNAO1; guanine nucleotide-binding protein G(o) subunit alpha isoform X1 [KO:K04534]
129496789  PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
129498637  PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
129507069  PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
129513452  PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
129520803  PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1 [KO:K02649]
129522073  PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta [KO:K02649]
129502645  PTK2; focal adhesion kinase 1 isoform X1 [KO:K05725] [EC:2.7.10.2]
129523357  PTK2B; protein-tyrosine kinase 2-beta isoform X1 [KO:K05871] [EC:2.7.10.2]
129507741  PXN; paxillin isoform X1 [KO:K05760]
129508118  CRKL; crk-like protein [KO:K04438]
129513703  CRK; adapter molecule crk isoform X1 [KO:K04438]
129508823  AKT3; RAC-gamma serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
129495892  AKT1; RAC-alpha serine/threonine-protein kinase [KO:K04456] [EC:2.7.11.1]
129499851  AKT2; RAC-beta serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
129517633  RAC-alpha serine/threonine-protein kinase-like [KO:K04456] [EC:2.7.11.1]
129514778  RAC-alpha serine/threonine-protein kinase-like [KO:K04456] [EC:2.7.11.1]
129513263  MTOR; serine/threonine-protein kinase mTOR [KO:K07203] [EC:2.7.11.1]
129501834  RPS6KB2; ribosomal protein S6 kinase beta-2 isoform X1 [KO:K04688] [EC:2.7.11.1]
129510988  RPS6KB1; ribosomal protein S6 kinase beta-1 isoform X1 [KO:K04688] [EC:2.7.11.1]
129521190  NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1 [KO:K02580]
129503049  RELA; transcription factor p65 isoform X1 [KO:K04735]
129496401  FOS; protein c-Fos [KO:K04379]
129497811  JUN; transcription factor Jun [KO:K04448]
129503119  BAD; bcl2-associated agonist of cell death [KO:K02158]
129494224  HRAS; GTPase HRas isoform X1 [KO:K02833]
129505561  KRAS; GTPase KRas isoform X1 [KO:K07827]
129501466  NRAS; GTPase NRas [KO:K07828]
129522592  RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1 [KO:K04366] [EC:2.7.11.1]
129506345  MAP2K1; dual specificity mitogen-activated protein kinase kinase 1 [KO:K04368] [EC:2.7.12.2]
129522322  MAP2K2; dual specificity mitogen-activated protein kinase kinase 2 [KO:K04369] [EC:2.7.12.2]
129502349  mitogen-activated protein kinase 3-like [KO:K04371] [EC:2.7.11.24]
129507918  MAPK1; mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
129519082  MAPK3; mitogen-activated protein kinase 3 [KO:K04371] [EC:2.7.11.24]
129500644  GNAQ; guanine nucleotide-binding protein G(q) subunit alpha [KO:K04634]
129522061  GNA11; guanine nucleotide-binding protein subunit alpha-11 [KO:K04635]
129493567  PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1 [KO:K01116] [EC:3.1.4.11]
129497753  PLCG2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 [KO:K05859] [EC:3.1.4.11]
129521608  ITPR1; inositol 1,4,5-trisphosphate receptor type 1 isoform X1 [KO:K04958]
129505465  ITPR2; inositol 1,4,5-trisphosphate receptor type 2 [KO:K04959]
129512495  ITPR3; inositol 1,4,5-trisphosphate receptor type 3 isoform X1 [KO:K04960]
129495972  CALM1; calmodulin-1 [KO:K02183]
129497741  CALML6; calmodulin-like protein 6 [KO:K02183]
129506414  CALML4; calmodulin-like protein 4 isoform X1 [KO:K02183]
129500769  CALM3; calmodulin-3 [KO:K02183]
129511712  CALM2; calmodulin-2 isoform X1 [KO:K02183]
129513685  calmodulin-like protein 3 [KO:K02183]
129513765  CALML5; calmodulin-like protein 5 [KO:K02183]
129523448  PPP3CC; serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform isoform X1 [KO:K04348] [EC:3.1.3.16]
129509604  PPP3CB; serine/threonine-protein phosphatase 2B catalytic subunit beta isoform isoform X1 [KO:K04348] [EC:3.1.3.16]
129521210  PPP3CA; protein phosphatase 3 catalytic subunit alpha isoform X1 [KO:K04348] [EC:3.1.3.16]
129495049  PPP3R2; calcineurin subunit B type 2 [KO:K06268]
129511439  PPP3R1; calcineurin subunit B type 1 [KO:K06268]
129495445  NFATC1; nuclear factor of activated T-cells, cytoplasmic 1 isoform X1 [KO:K04446]
129514485  nuclear factor of activated T-cells, cytoplasmic 1-like isoform X1 [KO:K04446]
129496345  NFATC2; nuclear factor of activated T-cells, cytoplasmic 2 isoform X1 [KO:K17332]
129497947  NFATC3; nuclear factor of activated T-cells, cytoplasmic 3 isoform X1 [KO:K17333]
129499558  NFATC4; nuclear factor of activated T-cells, cytoplasmic 4 [KO:K17334]
129494612  PRKCA; protein kinase C alpha type [KO:K02677] [EC:2.7.11.13]
129519978  PRKCB; protein kinase C beta type isoform X1 [KO:K19662] [EC:2.7.11.13]
129500385  PRKCG; protein kinase C gamma type [KO:K19663] [EC:2.7.11.13]
129497735  GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 [KO:K04536]
129520313  GNB2; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 [KO:K04537]
129503454  GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 [KO:K07825]
129498348  GNB4; guanine nucleotide-binding protein subunit beta-4 [KO:K04538]
129506463  GNB5; guanine nucleotide-binding protein subunit beta-5 isoform X1 [KO:K04539]
129496421  GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 [KO:K07826]
129501173  GNG3; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 [KO:K04540]
129499161  GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 isoform X1 [KO:K04541]
129520219  GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 [KO:K04542]
129520847  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5-like [KO:K04542]
129522362  GNG7; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 [KO:K04543]
129499702  GNG8; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 [KO:K04544]
129494664  GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 [KO:K04545]
129498223  GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 [KO:K04546]
129519244  GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 [KO:K04347]
129521436  GNG14; putative guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-14 [KO:K04347]
129519415  GNG13; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 [KO:K04547]
129498294  GNGT1; guanine nucleotide-binding protein G(T) subunit gamma-T1 [KO:K04548]
129512848  GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 [KO:K04549]
129519689  RAC1; ras-related C3 botulinum toxin substrate 1 isoform X1 [KO:K04392]
129511656  RAC2; ras-related C3 botulinum toxin substrate 2 isoform X1 [KO:K07860]
129513923  RAC3; ras-related C3 botulinum toxin substrate 3 isoform X1 [KO:K07861]
129506775  PAK1; serine/threonine-protein kinase PAK 1 [KO:K04409] [EC:2.7.11.1]
129503793  PAK2; serine/threonine-protein kinase PAK 2 [KO:K04410] [EC:2.7.11.1]
129517725  PAK3; serine/threonine-protein kinase PAK 3 isoform X1 [KO:K05733] [EC:2.7.11.1]
129499847  PAK4; serine/threonine-protein kinase PAK 4 [KO:K05734] [EC:2.7.11.1]
129496131  PAK5; serine/threonine-protein kinase PAK 5 [KO:K05736] [EC:2.7.11.1]
129504229  PAK6; serine/threonine-protein kinase PAK 6 isoform X1 [KO:K05735] [EC:2.7.11.1]
129520154  LIMK1; LIM domain kinase 1 isoform X1 [KO:K05743] [EC:2.7.11.1]
129507902  LIMK2; LIM domain kinase 2 isoform X1 [KO:K05744] [EC:2.7.11.1]
129502800  CFL1; cofilin-1 [KO:K05765]
129499502  CFL2; cofilin-2 [KO:K05765]
129513313  cofilin-1-like [KO:K05765]
129512779  TNF; tumor necrosis factor [KO:K03156]
129513994  TNFRSF1B; tumor necrosis factor receptor superfamily member 1B isoform X1 [KO:K05141]
129496481  BCL2L1; bcl-2-like protein 1 [KO:K04570]
129516767  TLR2; toll-like receptor 2 [KO:K10159]
129494517  TLR4; toll-like receptor 4 isoform X1 [KO:K10160]
129506934  MYD88; myeloid differentiation primary response protein MyD88 [KO:K04729]
129505651  IRAK4; interleukin-1 receptor-associated kinase 4 isoform X1 [KO:K04733] [EC:2.7.11.1]
129518585  IRAK1; interleukin-1 receptor-associated kinase 1 isoform X1 [KO:K04730] [EC:2.7.11.1]
129494142  TRAF6; TNF receptor-associated factor 6 isoform X1 [KO:K03175] [EC:2.3.2.27]
129511324  TAB1; TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 isoform X1 [KO:K04403]
129499952  TAB2; TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 [KO:K04404]
129512811  MAP3K7; mitogen-activated protein kinase kinase kinase 7 isoform X1 [KO:K04427] [EC:2.7.11.25]
129493669  CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1 [KO:K04467] [EC:2.7.11.10]
129515857  IKBKB; inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1 [KO:K07209] [EC:2.7.11.10]
129517602  IKBKG; NF-kappa-B essential modulator isoform X1 [KO:K07210]
129499457  NFKBIA; NF-kappa-B inhibitor alpha [KO:K04734]
129494481  interferon alpha-1/2-like [KO:K05414]
129494482  interferon alpha-1/2-like [KO:K05414]
129494483  interferon alpha-1/2-like [KO:K05414]
129494485  interferon alpha-1/2-like [KO:K05414]
129494486  interferon alpha-1/2-like [KO:K05414]
129494487  interferon alpha-1/2 [KO:K05414]
129494488  interferon alpha-1/2 [KO:K05414]
129494489  interferon alpha-1/2 [KO:K05414]
129494490  interferon alpha-1/2 [KO:K05414]
129494491  interferon alpha-1/2 [KO:K05414]
129494492  interferon alpha-1/2 [KO:K05414]
129494493  interferon alpha-1/2 [KO:K05414]
129494495  interferon alpha-1/2 [KO:K05414]
129494496  interferon alpha-1/2 [KO:K05414]
129494497  interferon alpha-1/2 [KO:K05414]
129494498  interferon alpha-1/2 [KO:K05414]
129494499  interferon alpha-1/2 [KO:K05414]
129494500  interferon alpha-1/2 [KO:K05414]
129494696  interferon alpha-1/2-like [KO:K05414]
129494819  LOW QUALITY PROTEIN: interferon alpha-2-like [KO:K05414]
129495209  interferon alpha-3-like [KO:K05414]
129495280  LOW QUALITY PROTEIN: interferon alpha-1/2-like [KO:K05414]
129495282  interferon alpha-1/2 [KO:K05414]
129494739  IFNB1; interferon beta [KO:K05415]
129511619  MAPK11; mitogen-activated protein kinase 11 isoform X1 [KO:K04441] [EC:2.7.11.24]
129511620  MAPK12; mitogen-activated protein kinase 12 isoform X1 [KO:K04441] [EC:2.7.11.24]
129512956  MAPK13; mitogen-activated protein kinase 13 isoform X1 [KO:K04441] [EC:2.7.11.24]
129512957  MAPK14; mitogen-activated protein kinase 14 isoform X1 [KO:K04441] [EC:2.7.11.24]
129494670  MAPK9; mitogen-activated protein kinase 9 isoform X1 [KO:K04440] [EC:2.7.11.24]
129501796  MAPK10; mitogen-activated protein kinase 10 isoform X1 [KO:K04440] [EC:2.7.11.24]
129522825  MAPK8; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
129512979  CGAS; cyclic GMP-AMP synthase [KO:K17834] [EC:2.7.7.86]
129513336  STING1; stimulator of interferon genes protein [KO:K12654]
129511757  TBK1; serine/threonine-protein kinase TBK1 isoform X1 [KO:K05410] [EC:2.7.11.10]
129499930  IRF3; interferon regulatory factor 3 isoform X1 [KO:K05411]
129511780  DNA dC->dU-editing enzyme APOBEC-3A-like [KO:K18750] [EC:3.5.4.-]
129512091  DNA dC->dU-editing enzyme APOBEC-3G-like isoform X1 [KO:K18750] [EC:3.5.4.-]
129512092  DNA dC->dU-editing enzyme APOBEC-3A-like [KO:K18750] [EC:3.5.4.-]
129497348  SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 isoform X1 [KO:K22544] [EC:3.1.5.-]
129521363  BST2; bone marrow stromal antigen 2 isoform X1 [KO:K06731]
129503428  TNFRSF1A; tumor necrosis factor receptor superfamily member 1A isoform X1 [KO:K03158]
129507824  RIPK1; receptor-interacting serine/threonine-protein kinase 1 [KO:K02861] [EC:2.7.11.1]
129497106  TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein isoform X1 [KO:K03171]
129505849  TRAF5; TNF receptor-associated factor 5 [KO:K09849]
129515072  TRAF2; TNF receptor-associated factor 2 [KO:K03173] [EC:2.3.2.27]
129497110  MAP2K3; dual specificity mitogen-activated protein kinase kinase 3 [KO:K04432] [EC:2.7.12.2]
129508745  MAP2K6; dual specificity mitogen-activated protein kinase kinase 6 isoform X1 [KO:K04433] [EC:2.7.12.2]
129521885  MAP2K7; dual specificity mitogen-activated protein kinase kinase 7 isoform X1 [KO:K04431] [EC:2.7.12.2]
129506047  FASLG; tumor necrosis factor ligand superfamily member 6 [KO:K04389]
129508172  FAS; tumor necrosis factor receptor superfamily member 6 [KO:K04390]
129503100  FADD; FAS-associated death domain protein [KO:K02373]
129523021  CASP8; caspase-8 [KO:K04398] [EC:3.4.22.61]
129503380  BID; BH3-interacting domain death agonist [KO:K04726]
129501028  BAX; apoptosis regulator BAX isoform X1 [KO:K02159]
129513046  BAK1; bcl-2 homologous antagonist/killer isoform X1 [KO:K14021]
129495480  apoptosis regulator Bcl-2 isoform X1 [KO:K02161]
129514527  apoptosis regulator Bcl-2 isoform X1 [KO:K02161]
129502969  cytochrome c [KO:K08738]
129506647  LOW QUALITY PROTEIN: cytochrome c-like [KO:K08738]
129515281  cytochrome c-like [KO:K08738]
129518214  cytochrome c-like [KO:K08738]
129513406  CASP9; caspase-9 [KO:K04399] [EC:3.4.22.62]
129503548  CASP3; caspase-3 isoform X1 [KO:K02187] [EC:3.4.22.56]
129514977  uncharacterized protein LOC129514977 [KO:K10784]
129497000  T-cell surface glycoprotein CD3 epsilon chain isoform X1 [KO:K06451]
129497001  T-cell surface glycoprotein CD3 gamma chain [KO:K06452]
129497002  T-cell surface glycoprotein CD3 delta chain [KO:K06450]
129508837  CD247; T-cell surface glycoprotein CD3 zeta chain isoform X1 [KO:K06453]
129513013  TAP1; antigen peptide transporter 1 [KO:K05653] [EC:7.4.2.14]
129512879  TAP2; antigen peptide transporter 2 [KO:K05654] [EC:7.4.2.14]
129512984  TAPBP; tapasin isoform X1 [KO:K08058]
129504167  PDIA3; protein disulfide-isomerase A3 [KO:K08056] [EC:5.3.4.1]
129522085  CALR; calreticulin [KO:K08057]
129499223  class I histocompatibility antigen, Gogo-OKO alpha chain-like isoform X1 [KO:K06751]
129512639  DLA class I histocompatibility antigen, A9/A9 alpha chain [KO:K06751]
129512971  DLA class I histocompatibility antigen, A9/A9 alpha chain-like isoform X1 [KO:K06751]
129513138  DLA class I histocompatibility antigen, A9/A9 alpha chain-like [KO:K06751]
129513147  DLA class I histocompatibility antigen, A9/A9 alpha chain-like [KO:K06751]
129507797  AP1B1; AP-1 complex subunit beta-1 isoform X1 [KO:K12392]
129497037  AP1G1; AP-1 complex subunit gamma-1 [KO:K12391]
129499479  AP1G2; AP-1 complex subunit gamma-like 2 isoform X1 [KO:K12391]
129522476  AP1M2; AP-1 complex subunit mu-2 isoform X1 [KO:K12393]
129521614  AP1M1; AP-1 complex subunit mu-1 [KO:K12393]
129517783  AP1S2; AP-1 complex subunit sigma-2 isoform X1 [KO:K12394]
129520217  AP1S1; AP-1 complex subunit sigma-1A [KO:K12394]
129522710  AP1S3; AP-1 complex subunit sigma-3 [KO:K12395]
129504074  B2M; beta-2-microglobulin [KO:K08055]
129519177  ELOB; elongin-B [KO:K03873]
129505368  ELOC; elongin-C [KO:K03872]
129500523  elongin-C-like [KO:K03872]
129497146  CUL5; LOW QUALITY PROTEIN: cullin-5 [KO:K10612]
129507307  RNF7; RING-box protein 2 isoform X1 [KO:K10611]
129521477  DCAF1; DDB1- and CUL4-associated factor 1 [KO:K11789] [EC:2.7.11.1]
129501514  DDB1; DNA damage-binding protein 1 [KO:K10610]
129516416  CUL4A; cullin-4A [KO:K10609]
129518270  CUL4B; cullin-4B isoform X1 [KO:K10609]
129496600  ATM; serine-protein kinase ATM isoform X1 [KO:K04728] [EC:2.7.11.1]
129507041  ATR; serine/threonine-protein kinase ATR isoform X1 [KO:K06640] [EC:2.7.11.1]
129497889  CHEK1; serine/threonine-protein kinase Chk1 isoform X1 [KO:K02216] [EC:2.7.11.1]
129495050  CDC25C; M-phase inducer phosphatase 3 isoform X1 [KO:K05867] [EC:3.1.3.48]
129504965  WEE1; wee1-like protein kinase isoform X1 [KO:K06632] [EC:2.7.11.1]
129515736  WEE2; wee1-like protein kinase 2 [KO:K06632] [EC:2.7.11.1]
129495258  LOW QUALITY PROTEIN: G2/mitotic-specific cyclin-B1-like [KO:K05868]
129497456  G2/mitotic-specific cyclin-B1-like [KO:K05868]
129509383  LOW QUALITY PROTEIN: G2/mitotic-specific cyclin-B1-like [KO:K05868]
129510308  LOW QUALITY PROTEIN: G2/mitotic-specific cyclin-B1-like [KO:K05868]
129514214  CCNB1; G2/mitotic-specific cyclin-B1 [KO:K05868]
129506320  CCNB2; G2/mitotic-specific cyclin-B2 isoform X1 [KO:K21770]
129518634  CCNB3; G2/mitotic-specific cyclin-B3 isoform X1 [KO:K21771]
129499207  CDK1; cyclin-dependent kinase 1 [KO:K02087] [EC:2.7.11.22 2.7.11.23]
Compound
C00076  Calcium cation
C00165  Diacylglycerol
C01245  D-myo-Inositol 1,4,5-trisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C20640  Cyclic GMP-AMP
Reference
PMID:22749173
  Authors
Evans VA, Khoury G, Saleh S, Cameron PU, Lewin SR
  Title
HIV persistence: chemokines and their signalling pathways.
  Journal
Cytokine Growth Factor Rev 23:151-7 (2012)
DOI:10.1016/j.cytogfr.2012.05.002
Reference
PMID:23806647
  Authors
Abbas W, Herbein G
  Title
Plasma membrane signaling in HIV-1 infection.
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Front Microbiol 4:34 (2013)
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Philos Trans R Soc Lond B Biol Sci 364:675-87 (2009)
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J Virol 85:11220-34 (2011)
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Related
pathway
npo03050  Proteasome
npo04010  MAPK signaling pathway
npo04020  Calcium signaling pathway
npo04064  NF-kappa B signaling pathway
npo04110  Cell cycle
npo04141  Protein processing in endoplasmic reticulum
npo04142  Lysosome
npo04150  mTOR signaling pathway
npo04151  PI3K-Akt signaling pathway
npo04210  Apoptosis
npo04612  Antigen processing and presentation
npo04620  Toll-like receptor signaling pathway
npo04623  Cytosolic DNA-sensing pathway
npo04668  TNF signaling pathway
npo04810  Regulation of actin cytoskeleton
KO pathway
ko05170   
LinkDB

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